ライフサイエンスコーパス: subclass

1 G1-4 subclasses, and anti-HLA-IgG (total and subclasses).

2 ss the future directions of this therapeutic subclass.

3 of chemical kingdom, super class, class, and subclass.

4 ently induced isotype switching to the IgG2c subclass.

5 pro-oncogenic pathways unique to this tumor subclass.

6 hylation was associated only with the former subclass.

7 brosides (HexCer), constitute a sphingolipid subclass.

8 -Nkx2.1(+) neurons are a distinct GPe neuron subclass.

9 s belonging to the large and extra-large HDL subclasses.

10 nvolved predominantly IgG2 and IgG3 antibody subclasses.

11 itions in the VLDL, IDL, and LDL lipoprotein subclasses.

12 ing questions at the level of RNA structural subclasses.

13 ssion of distinct immunoglobulin heavy chain subclasses.

14 definition qualifiers, were analyzed across subclasses.

15 estigate whether it segregates into distinct subclasses.

16 pared with the IgG1, IgG3, and IgG4 antibody subclasses.

17 complexity that further defines interneuron subclasses.

18 ae antibody responses in IgG(2a) and IgG(2b) subclasses.

19 d between the two groups, and even among the subclasses.

20 he specification of the two main interneuron subclasses.

21 , belong to different transcription response subclasses.

22 dissecting the differences among human tumor subclasses.

23 n of the connectivity patterns of inhibitory subclasses.

24 peline to classify HRGPs into 23 descriptive subclasses.

25 promoter and enhancer transcription response subclasses.

26 rmacokinetic properties of the corresponding subclasses.

27 were no correlations with LGI1/CASPR2-IgG1-4 subclasses.

28 on FcgammaR activation by the different IgG subclasses.

29 ich was reflected by less DSA in certain IgG subclasses.

30 nions from more abundant glycerophospholipid subclasses.

31 dy production predominantly of IgG1 and IgG3 subclasses.

32 nRK2.7, and SnRK2.8, and the ABA-independent subclass 1 protein kinases SnRK2.1, SnRK2.4, SnRK2.5, Sn

33 st interesting patterns of redundancy within subclass 1 SnRK2 protein kinases, with SnRK2.1, SnRK2.5,

34 We propose that subclass 1 SnRK2s function in root development under sal

35 We showed that subclass 1 SnRK2s, VCS, and 5' EXORIBONUCLEASE 4 (XRN4)

36 5 fimbrial family are subdivided into three subclasses (5a, 5b, and 5c) that share similar structura

37 These domains are found in all Subclass A ZIC proteins, but not in the Subclass B prote

38 genome into three main classes, and further subclasses: AAic (has a coding syntenic homolog), NTic (

39 Angiosperms carry two RPW8-NLR subclasses: ADR1 and NRG1.

40 cium-dependent protein kinase C conventional subclass alpha/beta leading to reduced phosphorylation o

41 Similar comparisons for flavonoids subclasses also did not show significant associations.

42 type 2 diabetes in youths by antidepressant subclass and according to duration of use, cumulative do

43 cule; IgG4 was the most predominant antibody subclass and antibodies to rLinB-13 did not cross react

44 murine backbones as either an IgG1 or IgG2a subclass and evaluated for binding to multiple F protein

45 The antibody subclass and functions that contribute to parasite clear

46 strate that IgA effector functions depend on subclass and glycosylation, and that disturbances in sub

47 e for all classification options (e.g. lipid subclass and individual fatty acid chains).

48 in humans emphasizes the importance of this subclass and points to the value of maintaining conforma

49 as demonstrated by the profiling of the IgG subclass and the expression of cytokines.

50 djacent long noncoding RNAs that define each subclass and validate the function of Myt1l in balancing

51 dentified 265 unique lipids across 20 lipids subclasses and 19 metabolites (284 in total) in mouse lu

52 roduce GAD65 antibodies of the IgG1 and IgG4 subclasses and are as abundant as B cells reactive for c

53 Levels of immunoglobulin G (IgG) subclasses and C1q fixation in response to Plasmodium fa

54 hingolipids were quantified and, considering subclasses and chemical structures of individual species

55 d extra-large high-density lipoprotein (HDL) subclasses and decreased levels of very low-density lipo

56 rphine, and bisbenzylisoquinoline structural subclasses and displaying a predominant R-enantiomeric c

57 re based on humanized or human IgG1, 2, or 4 subclasses and engineered variants.

58 existence of the human IgG1, IgG2, and IgG4 subclasses and explain the receptor-binding functions of

59 ques to classify subicular cells in distinct subclasses and have investigated their morphofunctional

60 mass spectrometry, we determined the glycan subclasses and heterogeneities at each head glycosylatio

61 al fragmentations of lipids across 117 lipid subclasses and included ion mobility tandem mass spectro

62 ations between habitual intakes of flavonoid subclasses and MRI-determined visceral (VAT) and subcuta

63 ople, driven primarily by differences in IgG subclasses and N-linked glycosylation of the CH2 domain.

64 ificant decrease of all immunoglobulins, IgG subclasses and pneumococcal polysaccharide antibodies.

65 ic unfolding signatures to differentiate IgG subclasses and provide more confident subclass categoriz

66 ive, namely nanobodies against all mouse IgG subclasses and rabbit IgG.

67 ways that associated to specific lipoprotein subclasses and revealed functional links between the gut

68 dly capture CIU data for a range of antibody subclasses and subtypes across all charge states simulta

69 ated with polyunsaturated long complex lipid subclasses and the C16-C20 FFAs but directly associated

70 uated by altering Anti-HLA Ab concentration, subclass, and detection reagents.

71 ctors, placental Fc receptor expression, IgG subclass, and glycan signatures and their association wi

72 (+) Th cell-dependent, dominated by the IgG1 subclass, and Id specific.

73 ne precursors, are often from the minor IgG3 subclass, and some are polyreactive, such as 4E10.

74 TCZ treatment for cAMR on total IgG, IgG1-4 subclasses, and anti-HLA-IgG (total and subclasses).

75 associated with altered translation of gene subclasses, and profound general secondary effects of RP

76 conclusion, AHAs specifically recognize IgG subclass- and protease-restricted hinge neoepitopes.

77 rticle concentration measures of lipoprotein subclasses; and 81 lipid and fatty acids ratios.

78 HDM-specific IgG subclass antibodies were determined by ELISA.

79 Antigen-specific IgG3 subclass antibodies were quantified in the same samples

80 Overall, proliferation subclasses are associated with a more aggressive phenoty

81 On the structural side, these subclasses are characterized by specific interchain disu

82 sceinated secondary Ab (2nd-Ab), whereas IgG subclasses are monitored with Fc-specific monoclonal who

83 new insights into this striatal interneuron subclass as important gatekeepers of goal-directed learn

84 d on disease endotypes, which are phenotypic subclasses associated with specific mechanisms underlyin

85 significant limitations to differentiate mAb subclasses at the intact level.

86 sed approach for the characterization of mAb subclasses at the middle level.

87 Additionally, the Subclass B proteins fail to elicit functional binding at

88 all Subclass A ZIC proteins, but not in the Subclass B proteins.

89 ly relevant BLs: class A CTX-M-15 and KPC-2, subclass B1 NDM-1 and VIM-2 MBLs, and the class C P. aer

90 Subclasses B1-3 comprised 19.1%, 52.2%, and 28.8% of B-P

91 and glycosylation, and that disturbances in subclass balance are associated with autoimmune disease.

92 s unequivocal distinction of these two lipid subclasses based on their chromatographic properties.

93 IgG2 is the second most abundant IgG subclass, being able to bind human FcgammaRII/FcgammaRII

94 n laryngeal gene mutations are found in both subclasses, better prognosis is strongly associated with

95 dual increase of all immunoglobulins and IgG subclasses, but values were always significantly lower t

96 of middle-level CIU of F(ab')(2) domains for subclass categorization of canonical and more complex ne

97 te IgG subclasses and provide more confident subclass categorization than CIU on intact mAbs.

98 We hypothesized DSA IgG subclass characteristics, compared to total DSA IgG, mig

99 We identified 2 subclasses, characterized by adaptive or exhausted immun

100 ity, and functional richness of springtails (Subclass Collembola), a major group of fungivores and de

101 onfidence interval [CI] 4.38-98.69) and IgG4 subclass composition >5% exhibited an OR of 8.99 (95% CI

102 fluorescence intensity (MFI) and normalized subclass composition (>5%).

103 immunoglobulin G (IgG) antibodies, but their subclass composition changed over time, with IgG1 persis

104 id cells and its differential binding of IgG subclasses controls the contributions of mast cells, bas

105 Patients with IgG subclass deficiency with IgA deficiency and those with C

106 gA deficiency (IgAdef), 10 patients with IgG subclass deficiency with IgA deficiency, and 223 age-mat

107 ation within the V region and is isotype and subclass dependent.

108 sophils, neutrophils, and macrophages to IgG subclass-dependent anaphylaxis.

109 3, followed by IgG1, was the predominant IgG subclass detected (seroprevalence range, 5%-35% for IgG1

110 Tumor subclasses differ according to the genotypes and phenoty

111 toire, there were significant differences in subclass distribution and, notably, the frequency of VH

112 not ancestral but was gained after the first subclasses diverged and that RNR subclasses with inhibit

113 ional gene regulatory principle for neuronal subclass diversification may be conserved from nematodes

114 The establishment of spinal motor neuron subclass diversity is achieved through developmental pro

115 rid nature of eculizumab as well as specific subclass domain assignments to the F(ab')(2) and Fc regi

116 ships were also explored for individual PFAS subclasses (e.g. PFSA, PFCA, etc.).

117 ) and CD8(+) T cells showed activation-based subclasses, each with a gradual decline from a cytotoxic

118 larly dense subclass-specific regulation and subclass-enriched transcription factor binding motifs.

119 ons and uncertainties, listing as a class or subclass(es) was ruled out, and an analog approach was u

120 e considered: evaluating HAAs as a class, as subclass(es), or as individual HAAs (analog approach).

121 case of endogenous retroviruses (ERVs), a TE subclass, experimental interrogation is constrained as m

122 The exhausted immune response subclass expressed many genes regulated by transforming

123 amine the effects of AIT on the IgE- and IgG subclass-expressing memory B cells.

124 s between total flavonoids and six flavonoid subclasses (flavonoid polymers, anthocyanins, flavan-3-o

125 nd 0.95, respectively) compared to other IgG subclasses for each antigen.

126 ultaneously, we single out putative neuronal subclasses for which future research can fill in existin

127 ion belong to a clade separated from the two subclasses forming R1-R2 octamers.

128 strikingly different affinities, these 3 IgG subclasses have been shown to enable induction of system

129 analyzed within the two major cartilaginous subclasses, Holocephali (chimaeras) and Elasmobranchii (

130 g the efficiency of our method for rapid mAb subclass identification at both intact and middle levels

131 Here, we show that the two IgA subclasses (IgA1 and IgA2) differ in their effect on imm

132 Immune complexes with subclasses IgG1 and IgG4 can in vitro be generated by pl

133 omplexes (ICs), but the role of the specific subclasses IgG1 or IgG4 in this phenotypic and functiona

134 inant anti-RhD IgG Abs of the four different subclasses (IgG1-4) with and without core fucose (i.e.,

135 hod by applying precisely defined ICs of the subclasses IgG4 or IgG1 constructed by two independent m

136 CIU to distinguish monoclonal antibody (mAb) subclasses, illustrating the efficiency of our method fo

137 ned scattering curves for two human antibody subclasses, immunoglobulin G (IgG) 1 and IgG4, on five d

138 s was used to detect hapten-specific IgG 1-4 subclasses in patient plasma.

139 We describe the roles of RGC subclasses in shaping unique developmental responses wit

140 n of Myt1l in balancing the ratio of the two subclasses in vitro.

141 Cellular subclasses include 2 distinct groups of resident macroph

142 are a class of specialized metabolites with subclasses including flavonols and anthocyanins, which h

143 In mice, the IgG subclass induced after Ag encounter can reflect the natu

144 Nevertheless, several phospholipid (PL) subclasses involved in stabilizing brain membranes were

145 ontaining gangliosides and other polar lipid subclasses is further purified by C18 solid-phase extrac

146 fference in transcriptional response between subclasses is the local chromatin environment.

147 ancing the biosynthesis of specific phenolic subclasses, is attracting interest among consumers.

148 ere profiled to capture variation in overall subclass/isotype abundance, neutralizing activity, and i

149 ar, evidence is accumulating that for RiPPs, subclasses known thus far may only represent the tip of

150 In two neuronal subclasses (L1 and L2), block with RIIIJ led to an incre

151 antagonist, Dendrotoxin-K, in several L-DRG subclasses (L1, L2, L3, and L5), suggesting the presence

152 We show that alloantibody concentration, subclass, laboratory-specific detection devices, subclas

153 Our RTT plot result for the subclass Lecanoromycetidae also reveals accelerated dive

154 ceae, and Peltigeraceae - which are from the subclass Lecanoromycetidae and mostly composed of macrol

155 the K-Pg mass extinction event on two major subclasses - Lecanoromycetidae and Ostropomycetidae - of

156 three levels of structural annotations: (i) "subclass level", e.g., PG(34:1); (ii) "fatty acyl level"

157 IgG subclass levels to allergens and peptides were determine

158 e homodimers that fall into two distinct GST subclasses: LigE homologues, which cleave the beta(R) st

159 clear AURKA can be recruited by Forkhead box subclass M1 (FOXM1) as a co-factor to transactivate FOXM

160 bservational associations of the lipoprotein subclass measures with risk of incident CHD in 3 populat

161 Skewing responses toward IgG(2) and IgG(4) subclasses might be a mechanism to suppress IgE-mediated

162 A large number of lipoprotein subclasses, myristoylcarnitine and palmitoylcarnitine, a

163 shows hybrid features of different supernova subclasses, namely a light curve that is typical of norm

164 t pharmacological inhibition of Forkhead box subclass O (FoxO) transcription factors using the small-

165 keto carbene species under study belong to a subclass of acyclic aminoarylcarbenes.

166 grase (IN) inhibitors (MINIs) are a distinct subclass of allosteric IN inhibitors.

167 propose that lugdunomycin represents a novel subclass of aromatic polyketides.

168 ses, suggesting this enzyme belongs to a new subclass of B(12)-dependent RS methylases.

169 A subclass of bacterial phytochromes (BphPs) utilizes heme

170 l NP superstructures are a rapidly expanding subclass of chiral nanomaterials in which NPs are arrang

171 om Clostridium botulinum, which belongs to a subclass of class I RNRs not studied before.

172 LDEW 8 (RPW8)-CC domain containing NLR (RNL) subclass of CNLs is encoded by 2 gene families, ACTIVATE

173 aining NrfA from G. lovleyi represents a new subclass of cytochrome c nitrite reductase.

174 The IL-36 subclass of cytokines may be important in regulating muc

175 nal hydrolases (UCHs) belong to an enzymatic subclass of DUBs, and are represented by three members i

176 Here, we focused on a subclass of EDCs that impacts the estrogen receptor (ER)

177 known to selectively assist the export of a subclass of effectors.

178 However, when that enzyme is a protease, a subclass of enzymes that hydrolyze other proteins, and t

179 m resolution revealed that it belongs to the subclass of FHA domains, which recognizes double-pSer/pT

180 tivity in somatostatin interneurons, a major subclass of GABAergic cells, is important to modulate lo

181 y a functionally and genetically homogeneous subclass of glutamatergic neurons defined by the express

182 nt lipid is shielded by the core domain of a subclass of glypicans defined by the Dally-like protein

183 Interestingly, a subclass of h-ChCs exhibits calretinin (CR) expression,

184 ity of cells with features of the progenitor subclass of HCC.

185 stability, leading to the formation of a new subclass of human ribosomal ultrafine anaphase bridges.

186 nd support the rationale for an IL-18-driven subclass of hyperinflammation.

187 These data reveal that the somatostatin subclass of inhibitory interneurons are driven by viscer

188 that D3 receptor expression defines a novel subclass of layer 5 glutamatergic pyramidal cell in mous

189 beneficial for diagnosing spitzoid tumors-a subclass of melanomas that present inherently ambiguous

190 zeolitic imidazolate frameworks (ZIFs) are a subclass of metal-organic frameworks (MOFs) amenable to

191 Of special interest is the subclass of metal-organic frameworks (MOFs) with pore ap

192 A subclass of molecular dioxygenases is the histone demeth

193 A subclass of neural stem and precursor cells (NPCs) expre

194 humans, and reveal a previously unrecognized subclass of neurodegenerative disease.

195 ular RNAs (circRNAs) are a covalently closed subclass of non-coding RNA molecules formed by back spli

196 idine analogues, thereby distinguishing this subclass of noncanonical agonists from previously define

197 ect-motion-sensitive RGCs, and a specialized subclass of nonimage-forming RGCs each had marked topogr

198 opose that PdaC is the first member of a new subclass of peptidoglycan MurNAc deacetylases.

199 In conclusion, we identified a subclass of peroxisomes, named "anaerobic" peroxisomes t

200 holesterol-dependent cytolysins (CDCs) are a subclass of PFTs widely implicated in food poisoning and

201 CMPs have become established as an important subclass of porous materials.

202 in substrate 2 (RAC2) is a member of the RHO subclass of RAS superfamily GTPases required for proper

203 n array of hybrid compounds from which a new subclass of receptor-selective antagonists was identifie

204 l(in)e-containing peptides (LAPs) comprise a subclass of RiPPs that display outstanding diversity of

205 t have enabled the fabrication of a specific subclass of scaffolded DNA origami objects called wirefr

206 signature had been clearly associated with a subclass of ssDNA-specific apolipoprotein B mRNA editing

207 The major subclass of the chlorogenic acids was identified as 5-ca

208 opionic acid receptors (AMPARs) constitute a subclass of the ionotropic glutamate receptor superfamil

209 mutant affecting p24 genes from the delta-1 subclass of the p24 delta subfamily (p24delta3delta4delt

210 pected roles of type I DNA topoisomerases, a subclass of these enzymes, in regulating gene expression

211 sferase (ChAT)-expressing interneurons are a subclass of vasoactive intestinal peptide (ChAT-VIP) neu

212 (MOFs) represent a particularly interesting subclass of zirconium MOFs due to the occurrence of seve

213 The correlation of classes/subclasses of antibodies against these antigens with cli

214 tochemistry, to comprehensively characterize subclasses of brain endothelial cells (ECs) under both n

215 focus on the current knowledge for the main subclasses of flavonoids, including anthocyanins, flavon

216 ebral organoids excessively produce specific subclasses of GABAergic interneurons and cause impaired

217 RSC neurons reliably distinguished different subclasses of hippocampal SPW-Rs according to ensemble a

218 Fc domains corresponding to each of the four subclasses of human and rhesus IgG and with Fc variants

219 ced TL1A was attributed to CD4(+) and CD8(+) subclasses of hVAT T cells.

220 IgG1 and IgG3 subclasses of IgG are potent effectors of complement- an

221 ippocampus, and differentiated into distinct subclasses of inhibitory interneurons expressing various

222 al modelling to comprehensively characterize subclasses of microglia in multiple regions of the centr

223 sence of spatially and temporally restricted subclasses of microglia in the central nervous system du

224 ains (VK3-20, VK1-5, and VK1-33) found among subclasses of naive human VRC01-class B cells and HIV br

225 als were highly selective even for different subclasses of narrow spiking cells and of broad spiking

226 motor-goal activity, complementarily in two subclasses of neurons.

227 ss averages of these complexes into discrete subclasses of particles helped reduce human bias.

228 MBCs capable of neutralizing distinct subclasses of pathogens, such as influenza and HIV, have

229 xpression and chromatin accessibility of two subclasses of projection neurons with divergent morpholo

230 tify successfully the transcription response subclasses of promoters and enhancers from two different

231 in FcgammaR-mediated responses to different subclasses of rhesus IgG.

232 ne biosynthesis (HMP-PP), and we outline new subclasses of SAM and tetrahydrofolate-binding RNA regul

233 , with the most striking changes seen within subclasses of sphingolipids.

234 on and bladder are innervated by specialized subclasses of spinal afferents, how these afferents beco

235 s nephropathy (MN), and define two molecular subclasses of this disease.

236 Specifically, three different subclasses of type 2 PG cells receive robust and target-

237 Thus, activation of specific subclasses of voltage- and/or calcium-gated potassium ch

238 In multiple datasets with known ground-truth subclasses, particularly on UK Biobank brain imaging dat

239 ic interneurons can be subdivided into three subclasses: parvalbumin positive (PV), somatostatin posi

240 ly neutralizing antibody from the major IgG1 subclass, PGZL1, which shares germline V/D-region genes

241 One subclass, phased siRNAs (phasiRNAs) require a trigger mi

242 PPD-specific isotype/subclass, PPD-specific antibody-dependent phagocytosis,

243 at adjuvants can dramatically impact the IgG subclass profile in macaques.

244 The IgG subclass profile showed a prevalence of cytophilic antib

245 IgG subclass profile was characterized by mean fluorescence

246 their effects on metabolite and lipoprotein subclass profiles.

247 ltaneously provides fine-grained lipoprotein subclass profiling and quantification of circulating fat

248 uropean ancestries with detailed lipoprotein subclass profiling from nuclear magnetic resonance spect

249 Combined, these data identify that IgG subclasses provide pathogen- and cell type-specific immu

250 Cross-linking of FcgammaRIIb by the IgG4 subclass redirects pro-allergic M2a macrophages to an M2

251 es-specific differences in FcgammaRs and IgG subclasses relative to humans.

252 The new periportal-type subclass represented 29% of all HCCs; expressed a hepato

253 loss of the coinnervating input, with the Ib subclass responding robustly compared with Is motoneuron

254 explored the diversity of protease- and IgG subclass-restricted AHAs and their potential as immunolo

255 ession of a single member of the p24 delta-1 subclass, RFP-p24delta5, which was dependent on the coil

256 Using this approach on other neuronal subclasses should ultimately accelerate the comprehensiv

257 days postinfection, and isotyping of the Ig subclass showed that the total IgG response switched fro

258 In addition, we identified that subclass-specific cytokine production is orchestrated at

259 lass, laboratory-specific detection devices, subclass-specific detection reagents all contribute to a

260 s in the form of Hox proteins to co-activate subclass-specific effector genes in post-mitotic motor n

261 atient data reveal that individuals carrying subclass-specific mutations differ clinically in their c

262 ranscription factors with particularly dense subclass-specific regulation and subclass-enriched trans

263 of a neuron class, but is also required for subclass-specific traits expressed along the A-P axis.

264 from the tetrahydroprotoberberine NMT (TNMT) subclass, specifically for GfTNMT from the yellow horned

265 (Nab) potential, and differences in antibody subclass, specificity, and Fc receptor ligation using ps

266 B cell clonal expansions and immunoglobulin subclass switch events were observed in diverse human ca

267 The IgG3-1 subclass switch interacts with B cell-receptor affinity

268 In subclass switching studies, murine IgG2a and humanized I

269 This cluster contains at least another subclass that is specified cooperatively by both dsx and

270 Kinesin and myosin motor families have a subclass that moves towards the opposite end of the micr

271 appearance of bradykinin-responsive neuronal subclasses that are relevant to chronic pain.

272 s the diversification of neuron classes into subclasses that share large sets of features but differ

273 y the existence of different Ig isotypes and subclasses, their varying serum concentrations, and the

274 ay predispose to SPOP mutant prostate cancer subclass through a hormone dependent DNA damage response

275 the binding patterns of both polyclonal IgA subclasses to commensals and glycan arrays and determine

276 ch to flow modules, distributing them in two subclasses: transformers and generators, which can be de

277 followed by definitive refinement, creating subclasses upon settling within the cortex, and lastly,

278 iously defined transcriptomic cell types and subclasses using the same transgenic mouse lines.

279 RSL proteins constitute a subclass (VIIIc) of the basic helix-loop-helix (bHLH) cl

280 a higher triglyceride composition within HDL subclasses was associated with higher risk of CHD, indep

281 each method accessed different exRNA carrier subclasses was determined by estimating the proportions

282 Notably, distribution of the B-POPF subclasses was influenced by institution and type of res

283 SNRIs-the most commonly used antidepressant subclass-was associated with an increased risk of type 2

284 Cs), or both expressing distinct IgA and IgG subclasses were identified in all patients with PADs.

285 lay a shift toward the pro-inflammatory IgA2 subclass, which is associated with higher disease activi

286 th the exception of high-density lipoprotein subclasses, which displayed a more heterogeneous respons

287 ification of 145 ganglioside species from 19 subclasses, which represents the highest number of repor

288 described a nitroimidazopyrazinone bicyclic subclass with promising antitubercular and antiparasitic

289 he possibility of exploiting IgG(3), the IgG subclass with superior activation of complement and abil

290 The GMM defined subclasses with downregulated (40%), unchanged (39%), up

291 Using monoclonal IgG subclasses with identical Ag specificity, our data demon

292 is a heterogeneous entity, where 3 distinct subclasses with increasing clinical and economic burden

293 r the first subclasses diverged and that RNR subclasses with inhibition mechanisms involving R1 oligo

294 and extensive class switching to IgG and IgA subclasses with limited somatic hypermutation in the ini

295 wever, it remains unclear whether fibroblast subclasses with non-overlapping functions also exist and

296 ues have been reported to assess intact IgGs subclasses, with recently special interest in native ion

297 tatin globally lowered levels of lipoprotein subclasses, with the exception of high-density lipoprote

298 ship execution mechanism includes a specific subclass within a neuronal cluster that co-express dsx a

299 ization of individual somatosensory neuronal subclasses within a mixed population.

300 ackbone that allows for switching of the IgG subclasses without altering target binding specificity t