ライフサイエンスコーパス: subcompartment

1 dendrites, where it was restricted to the ER subcompartment.

2 en the Vg1 3' untranslated region and the ER subcompartment.

3 e of SP might be heightened in this striatal subcompartment.

4 tuning protein exit or retention within each subcompartment.

5 heterochromatic B(2)(NeuN+) megabase-scaling subcompartment.

6 others also expressed it locally within each subcompartment.

7 , maintaining singular tuning curves in each subcompartment.

8 , indicating that BKPyV accumulated in an ER subcompartment.

9 us associations with potentially any nuclear subcompartment.

10 ast subsequently being detected in an acidic subcompartment.

11 s of membrane trafficking between organellar subcompartments.

12 hogen-induced alterations of specific tissue subcompartments.

13 s, we defined proteins enriched within these subcompartments.

14 anism for the specification of other somitic subcompartments.

15 he assembly and maintenance of the different subcompartments.

16 evealed interdigitating axonal and dendritic subcompartments.

17 membranes of both the sorting and recycling subcompartments.

18 ys that target proteins to other chloroplast subcompartments.

19 combinations of interstripe and thin stripe subcompartments.

20 ion, non-invasively, in live cells and their subcompartments.

21 hts into cell-to-cell variability of nuclear subcompartments.

22 tments on the inactive X harbouring multiple subcompartments.

23 en sorted by different systems to organellar subcompartments.

24 d global environment symmetry, even in local subcompartments.

25 to perform separation of early to late Golgi subcompartments.

26 o structural classes called compartments and subcompartments.

27 hromosomes in the human genome into distinct subcompartments.

28 ne second messengers to spatially restricted subcompartments.

29 one, to mix with FUS phase to form mRNA-rich subcompartments.

30 sting functional implications of single-cell subcompartments.

31 (PSII) assembly forms in different thylakoid subcompartments.

32 proteins residing in different mitochondrial subcompartments.

33 s, which are distributed into four different subcompartments.

34 of protein distributions in within cellular subcompartments.

35 ntain structurally and functionally distinct subcompartments.

36 imented streaming forms distinct cytoplasmic subcompartments.

37 zation of different ion channels in specific subcompartments.

38 elevated gene activity with respect to other subcompartments.

39 unclear how signaling is coordinated at both subcompartments.

40 erns of histone marks and segregate into six subcompartments.

41 the localization of Met in specific synaptic subcompartments.

42 proportions of protein partners in cellular subcompartments.

43 the discrete input pathways for different FB subcompartments.

44 utputs to be quantified in specific cellular subcompartments.

45 granules and might represent novel metabolic subcompartments.

46 ambiguously to one of the four mitochondrial subcompartments.

47 nal regulators in the specification of these subcompartments.

48 ate heretofore uncharacterized proepicardial subcompartments.

49 instead organize into functionally distinct subcompartments.

50 ulus is dependent on segregation of synaptic subcompartments.

51 ore, enhancing tumor, and FLAIR-hyperintense subcompartments), 1008 radiomic descriptors (eg, Haralic

52 dorsal compartment (71%) and in the lateral subcompartment (24%) of the ventral XII.

53 VISs were enriched in the nuclear subcompartment A1 and integrated into super-enhancers cl

54 We suggest that EV budding from cilia subcompartments acts as a safeguard mechanism to remove

55 endocytic system into biochemically distinct subcompartments allows for spatial and temporal control

56 The differentiation of physically distinct subcompartments also contributes to peroxisome diversifi

57 ecting the Igh locus to a repressive nuclear subcompartment and inducing the Igh locus to decontract.

58 otein)) are localized to their own endosomal subcompartment and interact with a wide range of protein

59 rticipate in the formation of this matrisome subcompartment and its striatofugal projections.

60 enables accurate classification of cellular subcompartments and achieves performance equivalent to a

61 cyte subproteomes vary between physiological subcompartments and how both astrocyte and neuronal SAPA

62 ntinual fusion and fission of stable, "like" subcompartments and provides a mechanism to grow the Gol

63 ent shuttling of CaMKIIa between the two PSD subcompartments and PSD condensate formation.

64 interface between proximal and distal Golgi subcompartments and that Golgi complex reformation after

65 to the fates of the three distinct nucleolar subcompartments and their associated protein machineries

66 ion became preferentially associated with A2 subcompartments and were constrained to the relative pro

67 detect differential regions at compartment, subcompartment, and boundary levels that are associated

68 ndrial membrane, specifically in the cristae subcompartment, and demonstrates that the mitochondrial

69 , independent of transcription, form nuclear subcompartments, and also indicates the potential of alt

70 re dynamically organized into shared nuclear subcompartments, and movement into or out of these facto

71 wever, many such RNP bodies contain internal subcompartments, and the mechanism of their formation re

72 00, A1, and A2 in different lipoproteins and subcompartments; and (c) MS-measured total serum phospha

73 Here we present scGHOST, a single-cell subcompartment annotation method using graph embedding w

74 However, subcompartment annotation, which requires Hi-C data with

75 TECSAS achieves high accuracy in predicting subcompartment annotations and reveals the influence of

76 architecture, designed to predict chromatin subcompartment annotations directly from epigenomic data

77 egions with conserved and cell-type specific subcompartment annotations have different patterns of fu

78 These hematopoietic subcompartments are composed of erythroblasts surroundin

79 n channel localization in distinct dendritic subcompartments are largely unknown.

80 Second, A1 and A2 subcompartments are segregated in 3D space through diffe

81 Prx1 distribution to distinct mitochondrial subcompartments are unknown.

82 y, our analysis identified different ciliary subcompartments as being specifically associated with di

83 on of altered distributions within metabolic subcompartments as well as conventional metabonomics con

84 We show that PfTPx-1 localizes to a nuclear subcompartment associated with active transcription on t

85 ess, superficial, and deep layers of defined subcompartments at baseline and follow-up in ACL-injured

86 The mean CVs for the subcompartments before and after exclusion of artifacts

87 revealed the presence of distinct chromatin subcompartments beyond the traditional A/B compartments

88 ruited in FUS assemblies to form TDP-43-rich subcompartments but without reciprocity.

89 cking OCAM show a redistribution of synaptic subcompartments, but the total area occupied by axonal i

90 ologically complex, partitioned into several subcompartments by a topologically elaborate two-membran

91 cific mRNAs in microscopically selected lung subcompartments by complementary DNA or RNA hybridizatio

92 x maintains Golgi enzymes in different Golgi subcompartments by retrograde protein trafficking.

93 ia in many cell types contain a periaxonemal subcompartment called the inversin compartment.

94 he endoplasmic reticulum (ER) at specialized subcompartments called exit sites (ERES).

95 he favoring nuclear differentiation and that subcompartments can be self-organized as a consequence o

96 The protocell subcompartments can sense extracellular signals, take ac

97 We conclude that Golgi subcompartments can separate one from the other.

98 ENCODE, shedding light on the links between subcompartments, cell identity, and epigenomic signals.

99 gate calcium signaling in multiple astrocyte subcompartments, concurrent with changes in cerebral art

100 synapses appear to be spatially isolated in subcompartments delineated by astrocyte processes.

101 nto acinar cells, whereas cells in the trunk subcompartment differentiate into endocrine and duct cel

102 retention signal, represent a privileged ER subcompartment distinct from that containing ER-retained

103 Scattering kinetics of Golgi subcompartments during microtubule disassembly and reass

104 omote Rab2-mediated vesicle budding at a VTC subcompartment enriched in recycling cargo.

105 atches (or striosomes) are limbic-associated subcompartments enriched in mu opioid receptors.

106 Twelve patients had detailed lymphocyte subcompartments evaluated.

107 nm-thick zone that potentially constitutes a subcompartment for achieving locally elevated [Ca(2+) ]

108 ith the inner scaffold, a crucial centriolar subcompartment for centriole size control and integrity.

109 e represented as occurring in two myoplasmic subcompartments for Ca(2+) distribution, one (T-space) a

110 We employed PYMB to predict subcompartments for over a hundred human cell types avai

111 ry infection period, to examine the anatomic subcompartment from which these cells are depleted, and

112 viorally relevant information onto dendritic subcompartments; global synaptic upscaling by deprivatio

113 e in these regions, which contain a membrane subcompartment harboring the early assembly factor PratA

114 Our results indicate that each Golgi subcompartment has a distinct phospholipid composition d

115 DA-approved drugs that can eradicate the CSC subcompartment in primary tumors may prevent metastatic

116 op radiomic features were obtained from each subcompartment in the training set on the basis of their

117 method for annotating single-cell 3D genome subcompartments in a broad range of biological contexts.

118 olarization, but the developmental origin of subcompartments in axons and dendrites is less well unde

119 ical response and the recovery of lymphocyte subcompartments in patients with metastatic melanoma.

120 serve differences between stalk and swelling subcompartments in the mature calyx.

121 ult in the relocation of different nucleolus subcompartments in transcription-stalled conditions.

122 ulates the levels of the protein in specific subcompartments, in particular the one containing the ac

123 and are correlated with molecular markers of subcompartments, including the lumen and walls of the ax

124 we develop a computational approach, SNIPER (Subcompartment iNference using Imputed Probabilistic Exp

125 ive oxygen species (ROS), the major cellular subcompartments involved and the overall cellular respon

126 obal scale but also within specific neuronal subcompartments, involving a wide range of molecules and

127 ondria; (iii) the mitochondria-associated ER subcompartment is enriched in enzymatic activities invol

128 tes because RNA contributed by relevant lung subcompartments is enriched.

129 ect positioning of CLL cells within lymphoid subcompartments is essential for the transmission of the

130 anelles are naturally segregated in cellular subcompartments is unclear.

131 ganization of eukaryotic cells into distinct subcompartments is vital for all functional processes, a

132 fy large-scale changes at the compartment or subcompartment levels, as well as local changes at bound

133 tifies cell-type-specific or allele-specific subcompartments linked to gene transcription across vari

134 tial segment (AIS) is a specialized neuronal subcompartment located at the beginning of the axon that

135 form a novel nuclear sub-compartment, called subcompartment M (subM), where MD-MD interactions occur

136 Similarly, the ventromedial subcompartment mainly rostrally, and the dorsal compartm

137 ate, suggesting that migration to functional subcompartments may influence gene expression.

138 Nuclear subcompartments may play a role by offering rich microen

139 de gliomas, pH(i) was increased in all tumor subcompartments (necrosis, 7.075 +/- 0.033; gadolinium e

140 per, a technique for isolating RNA from lung subcompartments obtained by microdissection is described

141 Dissociation of proteins from the other subcompartments occurred with faster kinetics but commen

142 yanobacterial LDs are a metabolically active subcompartment of cyanobacteria with dynamic morphology

143 also result from the existence of a specific subcompartment of endoplasmic reticulum regulating Icrac

144 CD1 family (CD1a-e) localizes to a distinct subcompartment of endosomes.

145 rcinoma cells with a growth factor-dependent subcompartment of malignant cells designated HCT116b tha

146 ondition, CaMKIIa is recruited to the Shank3 subcompartment of postsynaptic density (PSD) via phase s

147 renewing tissues of the body contain a small subcompartment of self-maintaining stem cells, upon whic

148 Our results define a distinct subcompartment of the C. elegans germ granule and sugges

149 Here, we identify an uncharted subcompartment of the C. elegans germ granule, which we

150 ion of C/EBPalpha in the non-heterochromatic subcompartment of the cell nucleus.

151 ndent gata2b expression within the hemogenic subcompartment of the dorsal aorta that is in turn requi

152 se activity itself, are highly enriched in a subcompartment of the endoplasmic reticulum (ER) that is

153 This may indicate that a specialized subcompartment of the endoplasmic reticulum functions as

154 ow that presenilins are highly enriched in a subcompartment of the endoplasmic reticulum that is asso

155 r cytoplasmic structure or possibly a unique subcompartment of the endoplasmic reticulum, and a cell-

156 t nuclear membranes lose their identity as a subcompartment of the ER during mitosis.

157 I to yield GlcN-PI, is largely confined to a subcompartment of the ER that appears to be associated w

158 and endogenous Vg1 mRNA is associated with a subcompartment of the ER.

159 (+) T cell loss predominated in the effector subcompartment of the GI mucosa, in distinction to the i

160 also provide evidence that the cristae are a subcompartment of the inner membrane.

161 The core subcompartment of the nucleus accumbens (NAcore) contrib

162 otoneuron pool, comprising the ventrolateral subcompartment of the nXII, was consistently and heavily

163 of caveolae microdomains, which represent a subcompartment of the plasma membrane.

164 ae are vesicular organelles that represent a subcompartment of the plasma membrane.

165 the dorsal compartment and the ventromedial subcompartment of the ventral compartment, where BDA lab

166 via the indirect pathway to the dorsolateral subcompartment of the ventral pallidum (dlVP) and throug

167 sor that allows H2O2 monitoring in all major subcompartments of a Chlamydomonas cell.

168 We investigated whether subcompartments of AT within the thigh are determinants

169 ments in solitary cells, multiple cells, and subcompartments of cells.

170 Thus, different subcompartments of colon tumors and adjacent normal tiss

171 It is well-established that subcompartments of endoplasmic reticulum (ER) are in phy

172 BM CD34(+) cells belonging to four subcompartments of increasing RNA content within the G0

173 phospholipid quaternary nitrogen methyls in subcompartments of lipoprotein particles) can give impor

174 going differential regulation within various subcompartments of live cells.

175 sed to identify proteins targeted to various subcompartments of mammalian cells, including the NE.

176 ed for the whole-tumor volumes (WTVs); tumor subcompartments of necrosis, gadolinium enhancement, and

177 e immunoreactivity (LIR) labels all cellular subcompartments of neurons and microglia, including thei

178 re differentially regulated across different subcompartments of neurons.

179 ry excitatory postsynaptic sites that act as subcompartments of signaling.

180 ce of circRNAs varies systematically between subcompartments of solid tumors and adjacent tissues, im

181 jority of D1-MSN in either the shell or core subcompartments of the accumbens collateralized to both

182 n size and differentiate into the definitive subcompartments of the AOTU, BU, and EB.

183 allows CD1 to sample lipid Ags from various subcompartments of the endocytic system.

184 Translocation of Ca2+ between distinct subcompartments of the endoplasmic reticulum is mediated

185 tively, human CD34(+) cells were isolated in subcompartments of the G0 /G1 phase of the cell cycle by

186 IIIbeta and PI4KIIalpha localize to discrete subcompartments of the Golgi complex in Madin-Darby cani

187 f several viruses that assemble in different subcompartments of the Golgi, as well as subcellular fra

188 -G was prominent in both proximal and distal subcompartments of the IS, where it colocalized with eit

189 ands the tight junction proteome and defines subcompartments of the junction.

190 Further, we show that subcompartments of the mitochondrial inner membrane exhi

191 aptic density proteins in the core and shell subcompartments of the nucleus accumbens were compared w

192 several hundreds of proteins in the various subcompartments of the organelle.

193 ng ventricular zone (VZ) and outer and inner subcompartments of the outer subventricular zone (OSVZ)

194 These subcompartments of the plasma membrane are characterized

195 that caveolae function as signal transducing subcompartments of the plasma membrane.

196 of ZO-1 are embedded in different functional subcompartments of the tight junction.

197 ction as both lipid biosynthesis and storage subcompartments of thylakoid membranes.

198 trate reliable identification of single-cell subcompartments, offering insights into cell-to-cell var

199 n, is accompanied by the separation of Golgi subcompartments one from another.

200 e manner or is targeted to specific neuronal subcompartments or synaptic sites to affect circuit func

201 the assignment of 818 proteins into the four subcompartments: outer membrane, inner membrane, interme

202 cell line, making it impractical to compare subcompartment patterns across cell types.

203 tomated delineation of medulloblastoma tumor subcompartments, potentially leading to more effective r

204 portance of various epigenomic marks in each subcompartment prediction.

205 ganize, we analyzed distributions of nuclear subcompartment proteins and assayed for caspase-induced

206 or caspase-induced cleavage of major nuclear subcompartment proteins during late erythropoiesis, in c

207 havior; similar regions within a dorsomedial subcompartment provide a domain-independent reconfigurat

208 sive elements in the loci, forming a genomic subcompartment, rather than by cohesion/CTCF-mediated ex

209 with correlated changes in chromatin states, subcompartments, replication timing and lamin associatio

210 king of NMDARs in this endoplasmic reticulum subcompartment requires both CASK and SAP97.

211 To demonstrate tumor subcompartment resolution, we validated the predicted tu

212 the glomerulus into the axonal and dendritic subcompartments, respectively.

213 ion of the germ cell cytoplasm into cellular subcompartments seems to be critical not only for the fl

214 -alpha activity, yet the isoparental HCT116b subcompartment showed similar levels of TGF-alpha expres

215 rised of stacked cisternal membranes forming subcompartments specialized for posttranslational proces

216 ing conformational and kinetic variations to subcompartment-specific actions of C/EBPalpha or any pro

217 provide a systematic protocol for cell- and subcompartment-specific labeling and identification of p

218 Here we used cell-specific and subcompartment-specific proximity-dependent biotinylatio

219 In particular, we develop a method to enrich subcompartment-specific RNA binding proteins (RBPs) by c

220 gomeric cargo is central to the mechanism of subcompartment specification.

221 In addition to being signalling subcompartments, spines also have unique morphological f

222 y, thereby losing proteins from key relevant subcompartments such as processes, end feet, dendrites a

223 nylation activities within the mitochondrial subcompartments, suggesting localized regulatory functio

224 localized to the endoplasmic reticulum (ER) subcompartment termed mitochondria-associated ER membran

225 a wider range of processes and environmental subcompartments than most previous models and considers

226 a transcription-initiation-dependent nuclear subcompartment that brings multiple nonloop domains in c

227 lum into a specialized endoplasmic reticulum subcompartment that bypasses somatic Golgi, merging inst

228 een chromosomes, and form a specific nuclear subcompartment that has elevated gene activity with resp

229 The endoplasmic reticulum (ER) consists of subcompartments that have distinct protein constituents,

230 regulated by the cellular organization into subcompartments that impose barriers to diffusion, can l

231 r the thymus and migrate through specialized subcompartments that support their maturation and select

232 and equally importantly, upon what cellular subcompartments the projections target.

233 When Rab2 binds to a VTC subcompartment, the subsequent recruitment of PKCiota/la

234 thetic thylakoid membrane generates two main subcompartments: the stacked grana core and unstacked st

235 to promote transport within the dendritic ER subcompartment, thereby restricting alpha7 trafficking t

236 terestingly, unlike previously characterized subcompartments, these interactions are present only in

237 enetic polymers encapsulated within targeted subcompartments to produce chemically organized multi-ti

238 domain surfaces, most strongly in chromatin subcompartments typically considered inactive.

239 ain; and (iv) the mitochondria-associated ER subcompartment, unlike bulk ER, is capable of the de nov

240 SNIPER accurately reveals subcompartments using moderate coverage Hi-C datasets an

241 nd multilayer perceptron classifier to infer subcompartments using typical Hi-C datasets with moderat

242 as detected in peroxisomes, but not in an ER subcompartment, using immunofluorescence microscopy.

243 Within the tumor subcompartments, VISTA is most highly expressed on CD11b

244 This endoplasmic reticulum subcompartment was composed of highly mobile vesicles co

245 tions, drug penetration into the various CNS subcompartments was not statistically different between

246 n ablating Notch signaling in different skin subcompartments, we find that this pathway exerts dual c

247 ants with glioma, the tumor volume and tumor subcompartments were compared with normal-appearing gray

248 Dendritic subcompartments were composed predominately of dendritic

249 The axonal subcompartments were composed primarily of ORC processes

250 ema, and cystic core plus nonenhancing tumor subcompartments, were performed by two experienced neuro

251 This work defines the nuclear periphery as a subcompartment where dangerous DNA elements can be handl

252 ts that these islands are highly specialized subcompartments where cell adhesion events, in concert w

253 s and was enriched within specific astrocyte subcompartments where it regulated actin cytoskeleton or

254 ATP is produced at the cristae, specialized subcompartments where oxidative phosphorylation (OXPHOS)

255 h a variety of different embedded functional subcompartments, which act as engineered synthetic organ

256 interchromatin space is composed of nuclear subcompartments, which are defined by several distinctiv

257 organize different substrates in concentric subcompartments, which can be then selectively addressed

258 no method exists for annotating single-cell subcompartments, which is important for understanding ch

259 l progenitors were present in G0 or early G1 subcompartments, while lineage-restricted granulomonocyt

260 m granule is compartmentalized into multiple subcompartments whose biological functions are largely u

261 ructure and protein arrangements in cellular subcompartments with so far unmatched resolution.

262 LAD clustering with Hi-C resulted in subcompartments, with lamin B1 and B2 partitioning to fa

263 ineate a potential transiently proliferating subcompartment within the basal cell compartment of the

264 se data show that SERCA2b is associated in a subcompartment within the sarcoplasmic reticulum of card

265 und between different tissue compartments or subcompartments within a given tissue.

266 ng for OMP and MAP2 revealed two distinctive subcompartments within glomeruli: an axonal compartment

267 unique proteins that associate with specific subcompartments within organelles.

268 ed the liposome localization in intratumoral subcompartments within spheroids.

269 er with computational modeling, to show that subcompartments within the nucleolus represent distinct,

270 ormation of membraneless organelles-cellular subcompartments without a lipid bilayer that perform spe

271 SNIPER enables the identification of subcompartments without high-coverage Hi-C data and prov