ライフサイエンスコーパス: subcomplex

1 ing modulators that target SF3B1 in the SF3b subcomplex.

2 complex with the human VPS29-VPS35 retromer subcomplex.

3 e-embedded VO region via rotation of a rotor subcomplex.

4 ith a 315-kDa subassembly, forms the 550-kDa subcomplex.

5 ents efficient formation of this midassembly subcomplex.

6 orting Pex10 and Pex12, but with the docking subcomplex.

7 nd the cargo-binding alphabeta'epsilon-COP B-subcomplex.

8 on of CENP-HIKM and of CENP-TW, another CCAN subcomplex.

9 hich along with APC1 form the APC/C platform subcomplex.

10 ic F1 region via rotation of a central rotor subcomplex.

11 d the trimeric Atg17-Atg31-Atg29 scaffolding subcomplex.

12 s a bridge between VPS34 and the ATG14:BECN1 subcomplex.

13 e Xeroderma pigmentosum B (XPB) and a kinase subcomplex.

14 for connecting the stalk to the catalytic F1 subcomplex.

15 king site for the formation of eIF3(a:b:i:g) subcomplex.

16 helices H68-70 during anchoring of the Rpf2 subcomplex.

17 nged with serovar F (N.I.1) from a different subcomplex.

18 in consecutive loss of CDK7 in the TFIIH-CAK subcomplex.

19 by a DNA-binding groove in the Cenp-L-Cenp-N subcomplex.

20 hat TIN2/TPP1/POT1 is a functional shelterin subcomplex.

21 itionally requires the CdK activating kinase subcomplex.

22 he cytosolic V1 and the integral membrane V0 subcomplex.

23 res that the SNAREs assemble into functional subcomplexes.

24 alyses of isolated FlaH and archaellum motor subcomplexes.

25 ture to favor assembly of Skp1/F-box protein subcomplexes.

26 s are released as individual molecules or as subcomplexes.

27 ghts into the structure and function of FoF1 subcomplexes.

28 he Rpc82/34/31 and Rpc53/37 Pol III-specific subcomplexes.

29 g the mutually exclusive composition of PRC2 subcomplexes.

30 ts than deletion of single MICOS subunits or subcomplexes.

31 fferent nucleoporins, typically organized in subcomplexes.

32 hilus with those of its membrane and soluble subcomplexes.

33 between IFT88/70/52/46 and IFT81/74/27/25/22 subcomplexes.

34 lex and the Nup93 complex, two conserved NPC subcomplexes.

35 einhardtii IFT70/52 and Tetrahymena IFT52/46 subcomplexes.

36 but finite exchange of even its most stable subcomplexes.

37 arity and structural independence of the IFT subcomplexes.

38 origins of the IFT-A, IFT-B, and the BBSome subcomplexes.

39 ic protein, C3orf1, were associated with the subcomplexes.

40 nto separate cavin1-cavin2 and cavin1-cavin3 subcomplexes.

41 Complex I is put together from preassembled subcomplexes.

42 l V(1) subcomplexes from membrane-bound V(o) subcomplexes.

43 by cryo-electron microscopy analysis of two subcomplexes.

44 e and the interactions between its different subcomplexes.

45 ybromo-associated BAF (PBAF) mSWI/SNF family subcomplexes.

46 higher-order oligomerization of nucleoporin subcomplexes.

47 nds on two evolutionarily conserved modules, subcomplexes A (IFT-A) and B (IFT-B), to drive ciliary a

48 nhibited V(1)-ATPase and V(o) proton channel subcomplexes, a process that is poorly understood on the

49 etry, crystal structure of the CPSF160-WDR33 subcomplex and biochemical assays, we define the molecul

50 1 and MICU2, among which MCU and EMRE form a subcomplex and function as the conductive channel while

51 comet)-dependent disassembly of a Cdc20-Mad2 subcomplex and identify it as Thyroid Receptor Interacti

52 he P- and L-ring genes, suggesting that this subcomplex and its persistence is an ancient and conserv

53 complex, comprising the Mis18alpha:Mis18beta subcomplex and M18BP1, is crucial for CENP-A homeostasis

54 ssociate with mtHsp70 as a hetero-oligomeric subcomplex and regulate mtHsp70 function.

55 nally, we discovered the presence of a CcoNQ subcomplex and showed that CcoN is the required anchor f

56 Importantly, the presence of the Nup84 pore subcomplex and Slx5/8 suppresses CAG repeat fragility an

57 teria, beginning with formation of the AcrAB subcomplex and suggest domains to target with efflux pum

58 s through a mechanism involving the shoulder subcomplex and the cytoskeletal-associated protein glyci

59 sponsible for the formation of eIF3(a:b:i:g) subcomplex and, because of mutually exclusive nature of

60 aled the presence of active CcoNQO and CcoNO subcomplexes and also showed that the CcoP subunit is no

61 RAVE) complex, which binds to cytosolic V(1) subcomplexes and assists reassembly with integral membra

62 ugh Dsc5, showing that the Dsc proteins form subcomplexes and display defined connectivity.

63 vealing both novel and previously identified subcomplexes and hub proteins, including Nop4.

64 m mitochondria lacking gRNA-bound RNP (gRNP) subcomplexes and identified REH2-associated cofactors 1

65 cose-dependent manner, positioning V1 and V0 subcomplexes and orienting the V1 C subunit to promote a

66 CI subunits demonstrated rapid generation of subcomplexes and revealed that their specific abundance

67 n of complexes, including the delineation of subcomplexes and subunit stoichiometry.

68 unfolded GLFG repeats as Velcro to link NPC subcomplexes and thus add a new layer of connections to

69 between the RNP catalytic core, p75-p19-p45 subcomplex, and the DNA-binding Teb1.

70 mass spectrometry measurements of complexes, subcomplexes, and subunits are necessary to build comple

71 sembly and spatial positioning of each MICOS subcomplex are poorly understood.

72 ow that inactive EGFR, LAPTM4B, and the Sec5 subcomplex are required for basal and starvation-induced

73 We further demonstrate that both subcomplexes are associated with intron RNA, which is a

74 into CI and CI+CIII(2), indicating that the subcomplexes are productive intermediates of assembly.

75 phic data obtained from the E1p-E2p didomain subcomplex as well as with other biochemical and NMR dat

76 or interaction with the membrane-embedded Fo subcomplex, as its transmembrane helix can be removed.

77 brane-spanning (subM) and the luminal (subL) subcomplexes, as well as subA, subB, and subE.

78 atalysis requires interaction of the protein subcomplex (BchX)2 with the catalytic (BchY/BchZ)2 prote

79 e experiments revealed a [4Fe-4S] cluster of subcomplex (BchX)2.

80 in a gamma-CA mutant is consistent with this subcomplex being a key initiator of CI assembly in plant

81 We here report the crystal structure of a subcomplex between E1p and an E2p didomain containing a

82 re designed, which suppress influenza PA-PB1 subcomplex binding to RanBP5 in a binary protein complem

83 ng, whereas the opposite face of the NELF-AC subcomplex binds NELF-B.

84 The NELF-AC subcomplex binds single-stranded nucleic acids in vitro,

85 ility was discovered in the E1p-E2p didomain subcomplex, both of which probably have consequences in

86 the crystal structure of a four-subunit T4CP subcomplex bound to the effector protein VpdB reveals an

87 S proteasome from 20 S proteasome and PA700 subcomplexes but has no effect on in vitro activity of t

88 ized roles and normally function in distinct subcomplexes but retain the ability to substitute for on

89 atory complex associates with the G9/A16 EFC subcomplex, but functional support for the importance of

90 tinating histone H2B, which is mediated by a subcomplex called the deubiquitinating module (DUBm).

91 ubcomplex, the BADC-facilitated BCCP-BADC-BC subcomplex can more readily interact with the CT-alphabe

92 The purified HoxEFU subcomplex catalyzed electron transfer reactions among N

93 also found evidence suggesting that the WRAD subcomplex catalyzes weak H3K4 monomethylation within th

94 the assembly and activation of BCCP-BADC-BC subcomplexes catalyzing the bicarbonate-dependent hydrol

95 teracted directly with the four-subunit CCAN subcomplex CENP-HIKM.

96 Deletion of genes encoding alignment subcomplex components, PilM or PilP, but not other T4P c

97 rane subcomplexes, connected by an alignment subcomplex composed of PilMNOP.

98 We identify a RQC-trigger (RQT) subcomplex composed of the RNA helicase-family protein S

99 One subcomplex, composed of Mic27/Mic26/Mic10/Mic12, require

100 SC activity and that UBAP2L is part of a PcG subcomplex comprising BMI1, we propose a model in which

101 are carried out by a lagging strand-specific subcomplex comprising DnaG, DnaEBs and DnaC, which stimu

102 netically and biochemically define a minimal subcomplex comprising just three proteins (FANCB, FANCL,

103 ochemical characterization of influenza RdRP subcomplex comprising PA, PB1, and N terminus of PB2, wh

104 re of NuRD by determining the structure of a subcomplex comprising RbAp48 and MTA1.

105 everal Gammaproteobacterial species, a relic subcomplex comprising the decorated P and L rings persis

106 nce, is composed of inner and outer membrane subcomplexes, connected by an alignment subcomplex compo

107 A subcomplex consisting of eIF3a, eIF3b, eIF3g, and eIF3i

108 r's tail module is highly dynamic and that a subcomplex consisting of Med2, Med3, and Med15 can be in

109 Cells lacking NDUFA9 contained a complex I subcomplex consisting of membrane arm subunits but not m

110 found that components of the inner membrane subcomplex consisting of PilMNOP were not essential for

111 Here we describe a heterotrimeric TFIID subcomplex consisting of the TAF2, TAF8 and TAF10 protei

112 of proteins called the divisome, of which a subcomplex consisting of three bitopic inner membrane pr

113 , to analyze the structure of a BBSome 2-7-9 subcomplex consisting of three homologous BBS proteins,

114 Each of these subcomplexes contain 9 +/- 2 cavin molecules and appear

115 This includes stable anchoring of the Rpf2 subcomplex containing 5S rRNA, rpL5, rpL11, Rpf2 and Rrs

116 the daughter cell requires members of an NPC subcomplex containing Nsp1p and its interacting partners

117 h other at endosomes and recruit the exocyst subcomplex containing Sec5.

118 MLL1 associates with a subcomplex containing WDR5, RbBP5, ASH2L, and DPY-30 (WR

119 ETd1A/B, which all interact with a conserved subcomplex containing WDR5, RbBP5, Ash2L, and DPY-30 (WR

120 on, suggesting the presence of low abundance subcomplexes containing CHT7 and MAT3/RB.

121 The 200-kDa subcomplex, containing the ancestral gamma-carbonic anhy

122 The individual RdRP subcomplex contains all the characterized motifs and app

123 ic components, and a peripherally associated subcomplex contributes to the membrane curvature.

124 size, thus enabling the removal of distorted subcomplex data in downstream models.

125 The resulting cells assemble only a subcomplex derived from the peripheral stalk and membran

126 assemblies that structurally mimic GCP2/GCP3 subcomplexes distal to the gamma-TuRC "seam." We also id

127 ected via Mic19, which functions to regulate subcomplex distribution, and thus, potentially also cris

128 The VPS34 catalytic domain and BECN1:ATG14 subcomplex do not touch, and it is unclear how allosteri

129 s, prefabrication of a native-like r-protein subcomplex drives efficient and accurate construction of

130 t (ESCRT), a molecular machinery of multiple subcomplexes (ESCRT-I/II/III) that promotes membrane rem

131 and CFIm68, we observed three CFIm distinct subcomplexes exist and CFIm59 protein level is dependent

132 ing sites, which are on different proteasome subcomplexes, explains the specificity of Ecm29 for prot

133 Electron microscopy confirmed that ESCRT-I subcomplexes form helical filaments in solution.

134 f and eIF3h, are stabilized by eIF3m through subcomplex formation.

135 We identify a NELF core subcomplex formed by conserved regions in subunits NELF-

136 t the reconstitution and characterization of subcomplexes formed by the cytoplasm-exposed synaptotagm

137 , we inferred that MET1 associates with PSII subcomplexes formed during the PSII repair cycle.

138 Among the subcomplexes formed were a-bI-alpha, bII-beta, alpha-bI-

139 ble nanoscale organization of these separate subcomplexes, forming individual striations on the surfa

140 The Mcm2-7 subcomplex forms a cracked-ring, right-handed spiral whe

141 Electrophysiology studies show that the Ton subcomplex forms pH-sensitive cation-selective channels

142 tal structure of a nucleotide-free Smc1-Scc1 subcomplex from Saccharomyces cerevisiae and Chaetomium

143 cose conditions by releasing peripheral V(1) subcomplexes from membrane-bound V(o) subcomplexes.

144 tic and biochemical evidence that a PTIP-PA1 subcomplex functions independently from the MLL3/MLL4 co

145 While kinetochore subcomplexes have been studied extensively in vitro, lit

146 in mammalian cells, the individual retromer subcomplexes have functionally diverged to organize mult

147 MICOS is organized into two independent subcomplexes; however, the mechanisms that dictate the a

148 structures of individual MAC components and subcomplexes; however, the molecular details of its asse

149 s a prerequisite for the correct assembly of subcomplex I.

150 This supercomplex contains two subcomplexes (I and II) that are responsible for trans-s

151 The IFT system consists of three subcomplexes [i.e., intraflagellar transport (IFT)-A, IF

152 comparing the structures and composition of subcomplex Ibeta and complex I, supported by comparisons

153 esolution X-ray crystallography structure of subcomplex Ibeta, a large portion of the membrane domain

154 mass spectrometry revealed that the largest subcomplex (IIa) represents the succinate dehydrogenase

155 Another subcomplex (IIb) is composed of the SDH3, SDH4, SDH6, an

156 corporation of new subunits into the 200-kDa subcomplex in a gamma-CA mutant is consistent with this

157 meric cohesin requires the Ctf19 kinetochore subcomplex in budding yeast [16-18].

158 ed that A56/K2 interacts with the G9/A16 EFC subcomplex in detergent-treated cell extracts.

159 nit of PRC2 to drive it into a PRC2.1 or 2.2 subcomplex in human induced pluripotent stem cells (iPSC

160 is dispensable for forming an active CcoNOP subcomplex in membranes.

161 We investigated the role of the Eaf3/5/7 subcomplex in NuA4 binding to nucleosomes.

162 approach to explore the role of Sec71-Sec72 subcomplex in post-translational protein translocation.

163 teins, are not associated with the hexameric subcomplex in the cytoplasm.

164 rowth in vivo by targeting the immature V(o) subcomplex in the endoplasmic reticulum (ER), thus provi

165 CcoP associates to CcoNQO subcomplex in the late maturation step, and once the Cco

166 for the assembly of DRC8, and DRC8/11 form a subcomplex in the proximal lobe of the linker domain tha

167 atin-remodeler form an abundant and distinct subcomplex in vivo and stimulate INO80-mediated activity

168 d our understanding of this highly conserved subcomplex, in part by demonstrating a direct interactio

169 reduced by phosphomimetic mutations on both subcomplexes, in an additive manner, indicating that bot

170 onstruction of an in vivo assembled effector subcomplex including the crRNA.

171 interactions with components of the BRCA1-A subcomplex, including ABRA1 and RAP80.

172 Our data suggest that MICOS subcomplexes independently localize to cristae junctions

173 which in turn determines how the MICU1-MICU2 subcomplex interacts with the MCU-EMRE channel and, cons

174 import showed the further assembly of these subcomplexes into CI and CI+CIII(2), indicating that the

175 s the first structure of an E1p-E2p didomain subcomplex involving a homodimeric E1p, and the results

176 The p75-p45-p19 subcomplex is identified as another RPA-related complex,

177 our results reveal a BRD9-containing SWI/SNF subcomplex is required for the survival of SMARCB1-mutan

178 IB proteins, indicating that the ankyrin-CIB subcomplex is required for TMC mechanosensitivity.

179 report that PHF5A, another component of this subcomplex, is also targeted by these compounds.

180 c80 outer kinetochore complex, but not other subcomplexes, is shed upon meiotic entry.

181 The essential nature of this subcomplex, its low abundance, and its multiple interact

182 ) coactivator, which contains a four-protein subcomplex known as the deubiquitinating (DUB) module.

183 SAGA contains a separable subcomplex known as the histone acetyltransferase (HAT)

184 cs and reveal the existence of an EZH1-SUZ12 subcomplex lacking EED.

185 3/5/7 within NuA4 came from mutations in the subcomplex leading to approximately 40% reductions in H4

186 in an additive manner, indicating that both subcomplexes make independent contributions to attachmen

187 ents captured for both intact assemblies and subcomplexes match expected values from available X-ray

188 of MICOS and identify two independent MICOS subcomplexes: Mic27/Mic10/Mic12, whose assembly is depen

189 es the major microtubule-binding kinetochore subcomplexes, Ndc80 and (in yeast) Dam1, to promote rele

190 n particular, the S-shaped Atg17-Atg31-Atg29 subcomplex of Atg1 is critical for phagophore nucleation

191 Previous results have implicated a conserved subcomplex of division proteins composed of FtsQ, FtsL,

192 hemoglobin (HbF) control is a non-redundant subcomplex of NuRD protein family paralogs, whose compos

193 rtant for the maintenance of the MRPP1-HSD10 subcomplex of RNase P and that loss of HSD10 causes impa

194 not affect Wapl-Pds5 binding to the cohesin subcomplex of sister chromatid cohesion protein 1 (Scc1)

195 onsists of a 10-subunit catalytic core and a subcomplex of subunits Rpb4 and Rpb7 (Rpb4/7).

196 nt of the cyclin-dependent activating kinase subcomplex of TFIIH).

197 h along with APC4 and APC5 form the platform subcomplex of the APC/C, is an additional target of the

198 EM structure of a human heterohexameric core subcomplex of the BBSome.

199 we present the first structure of the FdsBG subcomplex of the cytosolic FdsABG formate dehydrogenase

200 ough a mechanism dependent on the Nup107-160 subcomplex of the nuclear pore complex and is modulated

201 tion of this protein family, we focused on a subcomplex of the Saccharomyces cerevisiae RSC comprisin

202 cryo-EM structure of VopQ bound to the V(o) subcomplex of the V-ATPase.

203 ted, CMG unloading is inhibited, and a large subcomplex of the vertebrate replisome that includes DNA

204 lains the interdependency of the constituent subcomplexes of CCAN and shows how the Y-shaped opening

205 cking, suggesting that vesicles derived from subcomplexes of COPII coat proteins have a role in the s

206 dings of eIF3a and eIF3j to eIF3b, different subcomplexes of eIF3 likely exist and may perform noncan

207 It is also not clear whether or not some subcomplexes of MCC inhibit the APC/C and whether Mad2 i

208 CT chaperonin further binds and disassembles subcomplexes of MCC that lack Mad2.

209 Water-soluble subcomplexes of membrane-bound [NiFe]-hydrogenases (MBH)

210 Subcomplexes of mitochondrial respiratory complex I (CI;

211 We used purified subcomplexes of mitotic checkpoint proteins to examine t

212 isrupted, leading to accumulation of soluble subcomplexes of nuclear-encoded subunits.

213 ed differences in the subunit composition of subcomplexes of ovine complex I as compared with bovine,

214 and XPD ATPases, and how the core and kinase subcomplexes of TFIIH are connected.

215 Multiple protein subcomplexes of the kinetochore cooperate as a cohesive

216 We have previously proposed a model where subcomplexes of vRNA are exported from the nucleus and a

217 , Fap7 ATPase activity unloads the uS11:eS26 subcomplex onto its rRNA binding site, and therefore ens

218 Teb1, and the p75 subunit of the holoenzyme subcomplex p75/p19/p45.

219 electron tomography, here, we show that this subcomplex persists after flagellum disassembly in other

220 r pilin PilE depends on the putative priming subcomplex PilVWX and the non-pilin protein PilY1 for in

221 at mutant ESCs assemble atypical hybrid PRC2 subcomplexes, potentially accounting for enhancement of

222 Two mutually exclusive subcomplexes, PRC2.1 and PRC2.2, are defined by the set

223 a major component of an adaptor nucleoporin subcomplex proposed to link the NPC coat with the centra

224 Although the docking subcomplex proteins (Pex13, Pex14, and Pex17) also requi

225 othesis that HoxEFU is a distinct functional subcomplex rather than an artifact of Hox complex isolat

226 Phosphomimetics on either subcomplex reduced attachment lifetimes under constant f

227 ntified an RNA editing helicase 2-associated subcomplex (REH2C) and showed that REH2 binds RNA.

228 lation and in formation of the eIF3(a:b:i:g) subcomplex remain to be solved.

229 Removal of the WDR60-WDR34-light chain subcomplex renders dynein-2 monomeric and relieves autoi

230 The PP2A subcomplex required for stable G0 contains the B56gamma

231 For these exceptions, we find that distorted subcomplexes result from extreme disruption conditions,

232 ndant functions as the absence of both MICOS subcomplexes results in more severe morphological and re

233 rmined the crystal structure of a Zip2:Spo16 subcomplex, revealing a heterodimer structurally related

234 ponents of the Legionella core transmembrane subcomplex, revealing a well-ordered central channel tha

235 liberated upon dissection of complex II into subcomplexes, SDH6 and SDH7 also add some hydrophilic ma

236 ated by association with different accessory subcomplexes: SecYEG (forming SecYEG dimers) or SecDF-Ya

237 Cryo-EM and biochemical analyses of this subcomplex shows that ARP binding induces a helical conf

238 he crystal structure of the GON7/LAGE3/OSGEP subcomplex shows that the intrinsically disordered GON7

239 FA1 (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1) of complex I, thereby altering the

240 fied NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 (NDUFA9) and inosine-5'-monophospha

241 Here, we determine that MICOS subcomplexes target independently of one another to site

242 A recently identified SWI/SNF subcomplex termed GLTSCR1/1L-BAF (GBAF; or "noncanonical

243 d find additional functions of the Top3-Rmi1 subcomplex that are critical for the completion of meios

244 complex I and probably stabilizes a 400-kDa subcomplex that forms the initial nucleus of the periphe

245 We have discovered a PSII subcomplex that lacks 5 key PSII core reaction center po

246 eatments, the holo complex is dissected into subcomplexes that are analyzed by a three-dimensional ge

247 romatin-modifying complexes are organized by subcomplexes that harbor unique and distinct activities.

248 ase-resistant EMRE mutants produce uniporter subcomplexes that induce constitutive Ca(2+) leakage int

249 1 interactomes can be clustered into several subcomplexes that suggest novel DISC1 cell-specific func

250 irectly impact formation of the CT-alphabeta subcomplex, the BADC-facilitated BCCP-BADC-BC subcomplex

251 sis culminates with the joining of two large subcomplexes, the lid and base.

252 s regulatory particle (RP) consisting of two subcomplexes, the lid and the base.

253 plex (NDH-C) is assembled from five distinct subcomplexes, the membrane-spanning (subM) and the lumin

254 folding nups are organized in two multimeric subcomplexes, the Nup84 or Y complex and the Nic96 or in

255 ozens of kinetochore proteins organized into subcomplexes, the path of force transmission through the

256 The APC/C assembly contains two subcomplexes: the "Platform" centers around a cullin-RIN

257 The 26S proteasome can be divided into two subcomplexes: the 19S regulatory particle and the 20S co

258 Coatomer consists of two subcomplexes: the membrane-targeting, ADP ribosylation f

259 The APC/C assembly comprises two scaffolding subcomplexes: the platform and the TPR lobe that togethe

260 hat F(O)F1 is assembled in a modular way via subcomplexes, thereby preventing the formation of a func

261 aging, and budding of peroxisomal importomer subcomplexes, thereby preventing their premature assembl

262 solating mitochondria, we have identified CI subcomplexes through differences in (15)N incorporation

263 rmational switch in both FtsA and the FtsBLQ subcomplex to de-repress septal peptidoglycan synthesis

264 more readily interact with the CT-alphabeta subcomplex to facilitate the generation of malonyl-CoA.

265 h accessory proteins YidC and the SecDF-YajC subcomplex to form the bacterial holo-translocon (HTL).

266 that with FimU, PilE may couple the priming subcomplex to the major pilin PilA, allowing for efficie

267 PilXNm and PilVNm, likely connects a priming subcomplex to the major pilin, promoting efficient assem

268 Here we used heterologously expressed BBSome subcomplexes to analyze the complex architecture and to

269 quiring 66 subunits distributed over several subcomplexes to associate in a coordinated fashion.

270 ing of the MIS12 and NDC80 outer kinetochore subcomplexes to CENP-C and CENP-T.

271 ators include components of the spliceosomal subcomplex U1 small nuclear ribonucleoprotein (U1 snRNP)

272 ulatory particle, consisting of lid and base subcomplexes, undergoes major conformational changes who

273 subunit c of the V-ATPase membrane-embedded subcomplex V(o).

274 The formation of this subcomplex was critical for conferring stability to the

275 Proper fractionation of PSII super- and subcomplexes was achieved by critical selection of eluti

276 teracts with the Rags and is composed of two subcomplexes we call GATOR1 and -2.

277 d throughout the extremely stable Nup107-160 subcomplex, we refined our understanding of this highly

278 to study the assembly of these two essential subcomplexes, we here develop a set of twelve nanobodies

279 Using purified MGM and subcomplexes, we investigate the role of Mzt1 in MT nucl

280 try of the FtsQpBpLp complex and the FtsQpBp subcomplex were determined in complementary surface plas

281 mutations in the conserved PilMNOP alignment subcomplex were previously shown to have distinct effect

282 ften more compact and reflect native protein subcomplexes when compared with unmodified complexes act

283 o-EM structure of a six-protein core COMPASS subcomplex, which can methylate H3K4 and be stimulated b

284 Mediator contains the Cdk8 regulatory subcomplex, which directs periodic transcription and inf

285 ith the highly conserved YidC and SecDF-YajC subcomplex, which facilitates translocation into and acr

286 DNA repair, while the CDK-activating kinase subcomplex, which includes the kinase activity of CDK7 a

287 Far3, Far7, and Far8 form a subcomplex, which is recruited to the ER by Far9/10.

288 (Arf1):GTP-binding betagammadeltazeta-COP F-subcomplex, which is related to the adaptor protein (AP)

289 r membrane and forms a approximately 300 kDa subcomplex with complex IV subunits.

290 an mRNA-associated ribonucleoprotein (mRNP) subcomplex with editing substrates, intermediates, and p

291 somal central protuberance, assembles into a subcomplex with MrpL7 (uL5), Mrp7 (bL27), and MrpL36 (bL

292 on display reduced affinity to form a stable subcomplex with NFS1, and thereby fails to prevent NFS1

293 of RNA polymerase II (RNAP II) that forms a subcomplex with Rpb7, play important roles in transcript

294 the overall coat complex, and form distinct subcomplexes with cavin 1.

295 Both DnaJC15 and DnaJC19 formed two distinct subcomplexes with Magmas at the import channel.

296 I disrupted the assembly of the complex, and subcomplexes with masses of 550 and 815 kDa accumulated.

297 Eaf3, Eaf5, and Eaf7 form a subcomplex within NuA4 that may also function independen

298 n distinct conformations of the Rpn1-p28-AAA subcomplex within the p28-bound RP at subnanometer resol

299 e determined the structure of a four-protein subcomplex within the SWI/SNF remodeler that comprises t

300 tylation in regulating the formation of DUBm subcomplexes within the larger SAGA complex.