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1 ts part of the tasks of their parental gene (subfunctionalization).
2 g silenced in other organs, suggesting rapid subfunctionalization.
3 ular localization are similar to cis-element subfunctionalization.
4 ed zebrafish genes that do not show temporal subfunctionalization.
5  of Sox2-like properties fostered Sox family subfunctionalization.
6 ed from ancient duplications associated with subfunctionalization.
7  more instances of neofunctionalization than subfunctionalization.
8 of expression for gar genes, consistent with subfunctionalization.
9 tain the structural signature of splice form subfunctionalization.
10  forms among the duplicate genes - a form of subfunctionalization.
11 , higher transcript dosage, and evidence for subfunctionalization.
12 PE LIKE1 (GRL1), creating the possibility of subfunctionalization.
13 s of certain roles in a process described as subfunctionalization.
14 nce of their promoter activities and protein subfunctionalization.
15  in function through neofunctionalization or subfunctionalization.
16 nce of both overlapping redundancy and early subfunctionalization.
17  in a complementary fashion, perhaps driving subfunctionalization.
18 whole-genome duplication and, paradoxically, subfunctionalization after duplication can lead to relat
19  paralogue expression that were generated by subfunctionalization after genome duplication.
20     We describe the scope of transcriptional subfunctionalization and 15 cases of probable neofunctio
21 ed gene pairs and interpreted as evidence of subfunctionalization and a loss of redundancy.
22 resulted in independent instances of paralog subfunctionalization and maintained functional redundanc
23               However, the relative roles of subfunctionalization and neofunctionalization in the ret
24  are modified by gene gain and loss, by gene subfunctionalization and neofunctionalization, and by ch
25 ion in Leishmania donovani, emphasizing both subfunctionalization and neofunctionalization.
26 nctional specialization, with roles for both subfunctionalization and neofunctionalization.
27  CDY genes in simians spurred the process of subfunctionalization and possibly neofunctionalization.
28 tation, transposability of individual genes, subfunctionalization and/or fractionation of syntenic ge
29 tion compared to BZR1, hallmarks of neo- and subfunctionalization, and dynamic HSP90 client status ac
30  after duplication because they are prone to subfunctionalization, and gene complexity is regained vi
31 roles of conservation, neofunctionalization, subfunctionalization, and specialization in the preserva
32 Ps have retained ancestral functions through subfunctionalization, and subsequently, they acquired pa
33                                              Subfunctionalization appears to be a common phenomenon i
34                    Retargeting or regulatory subfunctionalization are common in the studied nucleus-e
35 , missing CNSs and a large insertion support subfunctionalization as a reflection of fractionation of
36  eudicot euAP1 and euFUL genes, we postulate subfunctionalization as the functional outcome after the
37 ng sequences of AUX/LAX genes have undergone subfunctionalization based on their distinct patterns of
38 nary novelties not based on gene duplication/subfunctionalization but by interactions in complex netw
39  preservation, increasing the probability of subfunctionalization but decreasing the probability of n
40 his paper, which could be termed subcellular subfunctionalization, complementary null mutations can o
41                               In cis-element subfunctionalization, complementary null mutations occur
42 ose that differential regulation and isoform subfunctionalization define starch-adaptive plasticity,
43             We found that in zebrafish, gene subfunctionalization due to ancestral duplication result
44 lication-Retention-Non/Neofunctionalization, subfunctionalization/duplication-degeneration-complement
45 k, likely reflecting the pathways of paralog subfunctionalization during evolution.
46                                 We present a subfunctionalization epistasis model to estimate the deg
47                                 The multiple subfunctionalization events that have occurred in this s
48 bers have undergone neofunctionalization and subfunctionalization events.
49 that expression reduction, a special type of subfunctionalization, facilitates the retention of dupli
50 and MYB42 syntelogs appear to have undergone subfunctionalization following gene duplication and dive
51             Together, these data reveal that subfunctionalization following gene duplication may be i
52 onserved target genes, suggesting that their subfunctionalization has evolved primarily via diverse p
53 rts and that lineage specific expansions and subfunctionalization have fashioned regulatory proteins
54 allel duplications and subsequent convergent subfunctionalization have resulted in the segregation to
55 ome-wide patterns indicative of homeoallelic subfunctionalization in a breeding population.
56  epigenetic modifications can drive neo- and subfunctionalization in evolution by gene duplication.
57 ted genes evolved separate functions through subfunctionalization in growth/development and stress re
58 3 lineage has undergone gene duplication and subfunctionalization in poppy, with one gene copy requir
59  and differential expression pattern suggest subfunctionalization in providing GGPP to specific tissu
60  a clear pattern of relaxed selection due to subfunctionalization in rhabdoviral glycoprotein paralog
61 ion may be related is through the process of subfunctionalization, in which an alternatively spliced
62             One consequence of polyploidy is subfunctionalization, in which the ancestral expression
63 tic pathways, partition ancestral functions (subfunctionalization) into divergent developmental modul
64                          The tissue-specific subfunctionalization is common to species of the Physali
65                                           If subfunctionalization is common, one expects duplicate ge
66                                              Subfunctionalization is evidenced by the observation tha
67                                              Subfunctionalization is the process by which a pair of d
68 ted but distinct biochemical processes; this subfunctionalization is tightly associated with epigenet
69 at functional divergence between duplicates (subfunctionalization) is caused by the loss of regulator
70 n gene duplication followed by co-option and subfunctionalization led to the emergence of globin fami
71 the complete function of the ancestral gene (subfunctionalization) may result in a requirement for bo
72 pulations, (ii) is quite consistent with the subfunctionalization model when degenerative but complem
73 and have provided evidence in support of the subfunctionalization model.
74 n-functionalization of one duplicate copy or subfunctionalization, neither of which yields novel func
75 including lineage-specific gene duplication, subfunctionalization, neofunctionalization and pseudogen
76                                  Relative to subfunctionalization, neofunctionalization is expected t
77 nd floral determinacy, unlike the pronounced subfunctionalization observed in Arabidopsis thaliana an
78 ization of 5AQ, pseudogenization of 5Bq, and subfunctionalization of 5Dq, all contributing to the dom
79                  These results might reflect subfunctionalization of a PcG protein during evolution.
80 ty, providing a framework to interrogate the subfunctionalization of ADs.
81 ingle-stripe elements arose by splitting and subfunctionalization of ancestral dual-stripe elements.
82  can include neofunctionalization as well as subfunctionalization of ancestral functions.
83 zebrafish and use it to provide evidence for subfunctionalization of Aqp0a and b, as well as to show
84 me duplication, suggesting the potential for subfunctionalization of chromatin regulation of paralogs
85 ion in Populus is driven by a combination of subfunctionalization of duplicate pairs and purifying se
86 ts provide new insights into tissue-specific subfunctionalization of duplicated exons in vertebrate e
87 tive for exploring the functionalization and subfunctionalization of duplicated genes in response to
88  mechanisms that may underlie germ-line/soma subfunctionalization of duplicated genes, taking into ac
89  46 human and 26 mouse tissues indicate that subfunctionalization of expression evolves slowly and is
90 nd evolutionary patterns contributing to the subfunctionalization of GAST domains, and explore functi
91  present two hepcidin types show a degree of subfunctionalization of its functions, with hamp1 more i
92  system for studying neofunctionalization or subfunctionalization of talin following the vertebrate t
93                              We also noticed subfunctionalization of the four Arabidopsis A1-type HSF
94  Schizosaccharomyces lineage may have led to subfunctionalization of the Mid1 orthologs.
95                               Therefore, the subfunctionalization of the O. tauri enzyme was differen
96                 From this analysis, we found subfunctionalization of the receptors in the control of
97 starch-related gene families and resulted in subfunctionalization of the respective gene products.
98                      This study affirms that subfunctionalization of the transcriptional regulatory e
99 eologs in tadpoles and adult frogs suggest a subfunctionalization of these homoeologs.
100 d the recently proposed alternatives such as subfunctionalization or duplication-degeneration-complem
101 ns, altered tissue expression, and potential subfunctionalization or neofunctionalization of HYDIN2 e
102 ntion with functional modifications (such as subfunctionalization or neofunctionalization) or loss.
103          The two copies can split functions (subfunctionalization) or can diverge to generate a new f
104 ifferential division of ancestral functions (subfunctionalization) or emergence of novel functions (n
105 olve their redundancy: neofunctionalization, subfunctionalization, or pseudogenization.
106  evolve by gene duplication, divergence, and subfunctionalization" parallel to models for the evoluti
107 en together, our results are consistent with subfunctionalization partitioning alternatively spliced
108 cal description of a system with alternative subfunctionalization paths.
109 evolutionary outcomes by independent neo- or subfunctionalization processes during the evolution of t
110 mong the possible fates of duplicated genes, subfunctionalization refers to duplicates taking on diff
111                             In contrast, the subfunctionalization (SF) hypothesis argues that duplica
112 popular models include neofunctionalization, subfunctionalization (SUBF) by degenerative mutations, a
113  non-coding sequences, false positive noise, subfunctionalization, synteny, annotation errors, invers
114 ication, which can be accomplished by either subfunctionalization (the partitioning of ancestral func
115  moellendorffii GAST, which further acquired subfunctionalization through successive conjugation of o
116                                              Subfunctionalization thus emerges as a fundamental featu
117 e become temporally restricted under partial subfunctionalization to particular stages of floret deve
118 volved through gene duplication, followed by subfunctionalization to specialize in repairing the nucl
119  hypothesis that the evolutionary process of subfunctionalization was responsible for the preservatio
120 and point mutations coupled to gene neo- and subfunctionalizations were involved in the evolution of
121  gene duplicates are frequently preserved by subfunctionalization, whereby both members of a pair exp
122 splayed a pattern indicative of homeoallelic subfunctionalization, while other traits showed a less c
123 eviously, it has been shown that splice form subfunctionalization will result in duplicate pairs with
124              PSY gene duplication has led to subfunctionalization, with each paralog exhibiting diffe
125 n an instance of an epigenetically modulated subfunctionalization within a BGC and sheds light on the
126 lines revealed functional overlap as well as subfunctionalization within members of the gene family.

 
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