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2 ared from progenitor cells obtained from the subventricular and the subgranular zones of adult mice b
5 adial glia (RG; neural stem cells) and their subventricular dispersion from the periventricular niche
7 rs, such as the ventricular radial glia, the subventricular intermediate progenitors, and the subvent
11 that outer radial glia directly support the subventricular niche through local production of growth
13 entricular intermediate progenitors, and the subventricular (outer) radial glia, have been identified
15 n 2-immunolabeled neurons in the ventricular/subventricular region, periventricular white matter, cen
18 red macrophages, adhered to the newly formed subventricular vascular plexus, and then divided into da
19 outer and inner subcompartments of the outer subventricular zone (OSVZ) in area 17 displayed unique m
21 ransit-amplifying cells that forms the outer subventricular zone (OSVZ), a proliferative region outsi
22 largely linked to the emergence of the outer subventricular zone (OSVZ), a uniquely structured germin
24 that WIP1 is expressed in NPCs of the mouse subventricular zone (SVZ) and aged animals with genetica
25 ng and recently divided cells in the rostral subventricular zone (SVZ) and hippocampus of DCX-TK tran
26 rinting for murine adult neurogenesis in the subventricular zone (SVZ) and in the subgranular zone (S
27 ration of bromodeoxyuridine (+) cells in the subventricular zone (SVZ) and lesioned cortex in the str
28 fying cells and neuroblasts in the postnatal subventricular zone (SVZ) and modulated the proliferatio
29 e correlation between protein changes in the subventricular zone (SVZ) and neurodegenerative diseases
30 olactin-stimulated adult neurogenesis in the subventricular zone (SVZ) and olfactory bulb (OB) mediat
31 interleukin 6 (IL-6) in the amplification of subventricular zone (SVZ) and subgranular zone (SGZ) neu
32 und in various parts of the brain, e.g., the subventricular zone (SVZ) and substantia nigra (SN), hav
33 as been attributed to the elaboration of the subventricular zone (SVZ) and the associated increase in
34 enhanced the endogenous neurogenesis in the subventricular zone (SVZ) and the dentate gyrus (DG) of
35 TBI) increases neurogenesis in the forebrain subventricular zone (SVZ) and the hippocampal dentate gy
36 brain plasticity in mammals occurring in the subventricular zone (SVZ) and the subgranular zone (SGZ)
37 directly to neural stem cells (NSCs) in the subventricular zone (SVZ) and to astrocytes in the adult
38 velopmental processes in the early postnatal subventricular zone (SVZ) are critical for proper brain
39 method, neural stem and progenitor cells of subventricular zone (SVZ) are isolated and expanded usin
40 neural precursor cells (NPCs) from the adult subventricular zone (SVZ) can also generate new oligoden
41 on of LIN28 in progenitor cells of the mouse subventricular zone (SVZ) caused several distinct effect
45 rogenitor cells (NSPCs) originating from the subventricular zone (SVZ) contribute to brain repair dur
46 ding that NK cells are retained in the brain subventricular zone (SVZ) during the chronic phase of mu
47 uman ganglionic eminences and found that the subventricular zone (SVZ) expanded massively during the
48 liferation and neuroblast chain formation in subventricular zone (SVZ) explants are compromised when
49 neural stem cells (NSCs) in the adult mouse subventricular zone (SVZ) express the histone methyltran
52 neural progenitor cells (NPCs) found in the subventricular zone (SVZ) have prompted strategies targe
55 gement of subdomains within the adult neural subventricular zone (SVZ) in vivo, we show distinct resp
56 s edematous T2 abnormality, mass effect, and subventricular zone (SVZ) involvement-were independently
59 ordinated regulation of the adult neurogenic subventricular zone (SVZ) is accomplished by a myriad of
64 es are continuously generated from nestin(+) subventricular zone (SVZ) neural progenitor cells (NPCs)
65 negatively regulates neurogenesis from adult subventricular zone (SVZ) neural stem cells (NSCs) in cu
66 Here, we report that loss of Tsc1 in mouse subventricular zone (SVZ) neural stem/progenitor cells (
67 to guide and contain newly generated rodent subventricular zone (SVZ) neuroblasts as they transit al
72 ular zone (SGZ) of the dentate gyrus and the subventricular zone (SVZ) next to the lateral ventricles
73 neural progenitor cells (NPCs) of the adult subventricular zone (SVZ) niche are fairly well understo
74 the neural stem cell (NSC) pool in the adult subventricular zone (SVZ) niche by preventing premature
75 ads to the expansion of these cells in their subventricular zone (SVZ) niches but fails to maintain s
76 low cytometry, adult mouse lateral ventricle subventricular zone (SVZ) NICs as Glast(mid)EGFR(high)Pl
77 d ischemic neural progenitor cells or in the subventricular zone (SVZ) of ischemic animals significan
78 as Srrt) is expressed by adult NSCs from the subventricular zone (SVZ) of mice, and that selective kn
79 ingle cell electroporation in the neurogenic subventricular zone (SVZ) of neonatal mice, we deleted T
80 isease (PD), neurogenesis is impaired in the subventricular zone (SVZ) of postmortem human PD brains,
84 ing neuronal recruitment from the neurogenic subventricular zone (SVZ) of the adult mouse striatum.
86 neuronal numbers in the cortex, striatum and subventricular zone (SVZ) of the ischemic rat brain, whi
87 ein (sAPP) as a vascular niche signal in the subventricular zone (SVZ) of the lateral ventricle of th
89 uced nestin lineage neural stem cells in the subventricular zone (SVZ) of the lateral ventricles and
90 in), and (d) neuronal maturity (NeuN) in the subventricular zone (SVZ) of the lateral ventricles and
91 egions where neurogenesis takes place is the subventricular zone (SVZ) of the lateral ventricles.
92 ortex via either modulation drives increased subventricular zone (SVZ) progenitor proliferation, migr
93 Dopaminergic signalling is necessary for subventricular zone (SVZ) proliferation and olfactory bu
96 l precursor cells (eNPCs) located within the subventricular zone (SVZ) since this latter area is cons
99 eural precursor cells (eNPCs) located in the subventricular zone (SVZ) to generate new OPCs in the le
100 iption factors increase in stem cells of the subventricular zone (SVZ) upon oncogenic stress, whereas
101 odel in which neural stem cells (NSC) of the subventricular zone (SVZ) were temporarily expanded by c
102 urogenesis persists postnatally in the human subventricular zone (SVZ) where slow-growing tumors cont
104 progenitor cell (NSPC) proliferation in the subventricular zone (SVZ), and migration of newly formed
105 e cell types in the preplate, marginal zone, subventricular zone (SVZ), and ventricular zone (VZ).
107 es and normal Pten/chr19 are observed in the subventricular zone (SVZ), but are distantly segregated
110 dant in the neurogenic regions including the subventricular zone (SVZ), rostral migratory stream (RMS
112 calization of beta-galactosidase outside the subventricular zone (SVZ), subarachnoid hemorrhage, and
113 ate neural stem cell quiescence in the adult subventricular zone (SVZ), the function of ECM in the de
114 re, we addressed microglial functions in the subventricular zone (SVZ), the major postnatal neurogeni
115 urogenic regions of the adult brain like the subventricular zone (SVZ), the rostral migratory stream
116 migration, we deleted RhoA and Cdc42 in the subventricular zone (SVZ), where more fate-restricted pr
118 We show that CNTF controls the migration of subventricular zone (SVZ)-derived neural progenitors tow
131 t neural stem cells (NSCs) within the rodent subventricular zone (SVZ; also called subependymal zone)
132 c niches in the adult brain, the ventricular-subventricular zone (V-SVZ) and the subgranular zone (SG
133 stem cells (NSCs) persist in the ventricular-subventricular zone (V-SVZ) and the subgranular zone (SG
134 Adult neural stem cells in the ventricular-subventricular zone (V-SVZ) contact the cerebrospinal fl
137 diate progenitors persist in the ventricular-subventricular zone (V-SVZ) of the adult mammalian brain
138 SCs) in different domains of the ventricular-subventricular zone (V-SVZ) of the adult rodent brain ge
140 neural stem cells (NSCs) in the ventricular-subventricular zone (V-SVZ) produce diverse olfactory bu
142 he adult neurogenic niche of the ventricular-subventricular zone (V-SVZ), beyond serving as a potenti
143 entiation in the young postnatal ventricular-subventricular zone (V-SVZ), in which neural stem cells
146 nal region of the forebrain, the ventricular-subventricular zone (V-SVZ), replenish olfactory neurons
149 gential migration along the ventricular zone/subventricular zone (VZ/SVZ) and intermediate zone (IZ)
150 l (RG) cells, in the neocortical ventricular/subventricular zone (VZ/SVZ), generate cortical projecti
151 yrus of the hippocampal formation and in the subventricular zone adjacent to the wall of the lateral
152 DeltaTK-GFP) transgene that labels quiescent subventricular zone adult neural stem cells also labels
153 d can similarly improve gene transfer to the subventricular zone after intraventricular injection.
155 arkably, along the germinal ventricular zone-subventricular zone and corpus callosum there is reduced
157 e quiescent neural stem cells from the adult subventricular zone and demonstrate their stem cell char
163 -diffraction-limit resolution-in the cortex, subventricular zone and olfactory bulb of mouse brain, u
164 nal progenitor cells located in the neonatal subventricular zone and persist in the adult murine cent
167 feration and an increase in apoptosis in the subventricular zone and rostral migratory stream of ERK5
168 inactivated in migrating neuroblasts in the subventricular zone and rostral migratory stream, and ac
170 ted Rad-NSCs were observed to persist in the subventricular zone and secondary Rad-NSCs were isolated
171 ls labeled from E12.5 contribute to both the subventricular zone and the dentate gyrus of the hippoca
172 ed in the adult brain, the lateral ventricle subventricular zone and the dentate gyrus subgranular zo
173 in the adult mammalian brain, including the subventricular zone and the dentate gyrus, which act to
174 striatal neuroglia, with gliogenesis in the subventricular zone and the somatosensory cortex in vivo
175 urogenesis, not all new neurons in the human subventricular zone are destined for the olfactory bulb-
176 adult neural stem cells resident within the subventricular zone are known sources of remyelinating c
179 mined stem cells residing in the ventricular-subventricular zone continuously generate progenitors th
180 accumulation of neuronal progenitors in the subventricular zone during corticogenesis, and impaired
184 roughout life, stem cells in the ventricular-subventricular zone generate neuroblasts that migrate vi
187 rter NKCC1 (shNKCC1) in NPCs of the neonatal subventricular zone in mice to reduce GABA(A)-induced de
188 d by ventricular radial glial (RG) cells and subventricular zone intermediate progenitor (IP) cells.
189 The length of time that cells stay in the subventricular zone is essential for controlling further
190 ontinuous supply of new neuroblasts from the subventricular zone is necessary for both the restoratio
191 rogenesis in the subgranular zone and/or the subventricular zone is responsible for the social abnorm
192 liferation of neural progenitor cells in the subventricular zone leads to the continuous generation o
193 om microarrays, and FACS purification of the subventricular zone lineage, we stringently identify lnc
194 and adult CNS, Plexin-B2 is expressed in the subventricular zone lining the telencephalic ventricles
199 nterior forebrain.SIGNIFICANCE STATEMENT The subventricular zone neurogenic stem cell niche generates
200 acts NPCs proliferation and migration at the subventricular zone niche and results, for the first tim
202 as-homolog enriched in brain (Rheb(CA)) into subventricular zone NPCs increased mTOR activity in newb
203 shRNA mediated knockdown of Rab27a in dorsal subventricular zone NSCs and astrocytes increased the nu
206 increased infiltration of microglia into the subventricular zone of both FIP200hGFAP conditional knoc
209 proteins) 1, 5, and 8, were elevated in the subventricular zone of human infants with HIE compared t
213 t mouse brain contain neural stem cells: the subventricular zone of the anterior forebrain and the su
214 ural stem and progenitor cells reside in the subventricular zone of the brain, intraventricular injec
217 entate gyrus of the hippocampus and from the subventricular zone of the lateral ventricle, the rostra
218 mmalian brains, neurogenesis persists in the subventricular zone of the lateral ventricles (SVZ) and
219 re part of the neurogenic niche in the adult subventricular zone of the lateral ventricles, where the
221 decrease in neurogenesis is observed in the subventricular zone of the LGE at mid-stages of embryoge
222 aled that the migration and proliferation of subventricular zone OPCs is decreased in the Cav1.2(KO)
223 hin the brain, endothelial cells (EC) of the subventricular zone play a critical role in neural stem
224 tively regulated both OPC specification from subventricular zone progenitors as well as the balance b
228 ime-lapse imaging of multipolar cells in the subventricular zone revealed that downregulating levels
230 h glioblastoma that contacts the ventricular-subventricular zone stem cell niche (VSVZ + GBM) have a
231 hey became transcriptionally very similar to subventricular zone stem cells, progressing through a ne
232 d GCs by sparse retroviral delivery in mouse subventricular zone that allows functional analysis of s
234 show that these cells are recruited from the subventricular zone to populate demyelinated lesions in
237 me apparently long-range (extending from the subventricular zone to the ventricular zone), and some s
238 glial cells and seed formation of the outer subventricular zone via horizontal divisions, which occu
242 sis by outer radial glial cells in the outer subventricular zone, a region present in humans but not
243 In mice, Chi3l3 is highly expressed in the subventricular zone, a stem cell niche of the adult brai
244 on molecule Contactin2, defasciculate in the subventricular zone, and fail to grow toward the midline
245 of the hippocampal formation, but not in the subventricular zone, and, as a novel finding, affected m
246 al stem cells (NSC) harvested from Mut3 mice subventricular zone, and, in vivo, there was increased p
247 born pyramidal neurons migrating through the subventricular zone, but not in those migrating through
248 he number of newly formed neuroblasts in the subventricular zone, corpus callosum and the peri-infarc
250 dly by progenitors in the embryonic day 15.5 subventricular zone, during the peak of superficial laye
253 precursors, generated throughout life in the subventricular zone, migrate through the rostral migrato
254 Prominin-1(+) precursor cells from the adult subventricular zone, no information about the expression
255 losum and reduced cell division in the mouse subventricular zone, the hippocampal dentate gyrus, and
256 postnatal day 4 NSCs and adult NSCs from the subventricular zone, transplanted Rad-NSCs differentiate
257 Moreover, AKNA regulates the exit from the subventricular zone, which reveals the pivotal role of c
258 the ventricular zone and progenitors in the subventricular zone, with the contribution from each reg
259 t hours of neuronal differentiation of adult subventricular zone-derived stem/progenitor cells, we de
260 vRG) that express ANXA1 and CRYAB, and outer subventricular zone-localized RG (oRG) that express HOPX
286 ave defects in postnatal neurogenesis in the subventricular zone: a developmental continuum that resu
287 ursors in the embryonic ventricular (VZ) and subventricular zones (SVZ), which give rise to excitator
288 al stem cells located in the ventricular and subventricular zones along the lateral forebrain ventric
290 imal differences between the inner and outer subventricular zones even though the outer zone is expan
291 s in the transient embryonic ventricular and subventricular zones generate neurons that migrate acros
293 zed that neurogenesis in the ventricular and subventricular zones of the cerebral cortex would contin
294 idal neurons are born in the ventricular and subventricular zones of the pallium and migrate along ra
295 and 8 months of age, whilst others, like the subventricular zones, these differences were more eviden
296 to cellular retention in the ventricular and subventricular zones, whereas overexpression of Botch dr