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1 tection; whereas 100% of the control animals succumbed.
2 with 7 x 10(5) TCID(50) of A/Vietnam/1203/04 succumbed.
6 scence occurred within 4 to 9 days, and mice succumbed approximately 10 to 20 days after treatment te
9 hy until both developed cancer to which they succumbed at the ages of 10 and 12 years, respectively.
15 c(+) dendritic cells and LysM(+) macrophages succumbed completely to DENV infection, while mice defic
16 Importantly autophagy-restored mice still succumb earlier due to an increase in spontaneous tumour
21 ow that these Clec9a(Kras-G12D) mice rapidly succumb from disease and display massive accumulation of
22 vely well, whereas mice producing GM-CSF can succumb from left ventricular rupture, a complication mi
27 infection and observed MIF-deficient mice to succumb more quickly with higher organism burden, increa
28 e suffer more severe damage in the colon and succumb more rapidly from acute radiotoxicity than the c
29 die mutant flies have shortened lifespan and succumb more rapidly than controls when infected with Si
31 IL-36beta, but not IL-36alpha or IL-36gamma, succumbed more frequently to HSV-1 infection than wild t
32 e is unexpectedly preserved into later life, succumbing only in extreme old age due to the acquisitio
36 ion, as mice lacking the type I IFN receptor succumb rapidly following infection and have high levels
37 ific, actin-bundling protein L-plastin (LPL) succumb rapidly to intratracheal pneumococcal infection.
38 Nevertheless, whereas IFN-gamma(-/-) mice succumb rapidly to STm infections, T-bet(-/-) mice do no
42 ose concentration by 40%, and the mosquitoes succumb sooner after exposure to desiccation or heat.
44 D485N]) develop autoimmunity as they age and succumb to a disease resembling lupus nephritis in human
45 enomegaly, anemia, and thrombocytopenia, and succumb to a rapidly progressing and fully penetrant neo
48 ted toxicity, causing all treated animals to succumb to acute pancreatitis and hyperglycemic coma.
49 ithelial ovarian cancer (EOC) patients often succumb to aggressive metastatic disease, yet little is
50 s of correct proximo-distal patterning, they succumb to apoptosis from embryonic day 9.75 onwards.
53 how that mice chronically infected with CL13 succumb to challenge with ectromelia virus (ECTV; the ag
54 coccal polysaccharide-specific responses and succumb to challenge with live type 3 serotype pneumococ
58 asitological features of human infection but succumb to chronic paralyzing myositis and skeletal musc
60 s lacking subdued gene activity more readily succumb to death caused by ingesting the pathogenic bact
65 ic deletion of BCAP fail to recover from and succumb to dextran sulfate sodium-induced colitis due to
66 myeloma (MM), nearly all patients ultimately succumb to disease relapse and progression despite new t
69 ts and when challenged by certain stressors, succumb to enhanced tumour development and aneuploidy.
71 Women suffering from breast cancer often succumb to incurable recurrent disease resulting from th
72 expression in T cells (GR(lck-Cre)) rapidly succumb to infection despite displaying parasite burdens
74 the hcl1 mutant took significantly longer to succumb to infection than mice infected with the wild-ty
75 the total number of amphibians predicted to succumb to infection was driven by a few high mortality
84 xpressing breast carcinoma cells that do not succumb to lapatinib, this Her1/2 inhibitor disrupts the
85 onstrated that mice maintained on a VLP diet succumb to lethal challenge at greater rates than mice m
87 ns of genital herpes disease; and 4) did not succumb to lethal infection (p < 0.005) after intravagin
88 ent in both pathways fail to control IAV and succumb to lethal respiratory infection, RIPK3-mediated
94 d neutrophils (polymorponuclear cells, PMNs) succumb to M. tuberculosis within 30 days, an extremely
95 n vivo tumorigenesis, Apc(min/+) mice, which succumb to massive intestinal polyposis, were bred to Ct
97 atic ductal adenocarcinoma (PDAC) invariably succumb to metastatic disease, but the underlying mechan
98 ndary malignant tumor in patients who do not succumb to metastatic melanoma within the first few post
99 most B6 mice chronically infected with CL13 succumb to mousepox but that most of those that recovere
100 mporal lobe (MTL) is the first brain area to succumb to neurofibrillary tau pathology in Alzheimer's
102 sea cucumber fisheries throughout the world succumb to overexploitation driven by rising demand, the
103 m ovarian cancer usually occur when patients succumb to overwhelmingly numerous and widespread microm
104 1 and demonstrated that Chil1-deficient mice succumb to P. aeruginosa infection more rapidly than the
105 ar cells accumulate ZGs, but the mice do not succumb to pancreatic damage or worse pancreatitis outco
108 e lacking both IFN-I and IFN-gamma receptors succumb to R. parkeri, revealing critical and overlappin
112 imals homozygous for asparagine at codon 146 succumb to scrapie under natural conditions.IMPORTANCE I
114 (Sf) mice, which are deficient in Tregs and succumb to severe multiorgan inflammation by 4 weeks of
115 isingly, unlike p53 null mice, which rapidly succumb to spontaneous thymic lymphomas, early-onset tum
120 only chance of long-term survival, 80% still succumb to the disease and approximately 30% die within
121 survive initial ASF infection but eventually succumb to the disease are key for the long-term persist
124 Despite aggressive therapy, many patients succumb to the disease, and survivors experience severe
135 ility of photoreceptors that otherwise could succumb to the high metabolic flux and photo-oxidative s
136 CB17 SCID mice infected with R. typhi(GFPuv) succumb to the infection with kinetics similar to those
139 he intricacies of the human mind, waiting to succumb to the powerful, objective, and reliable percept
141 , yet 40% to 50% of patients will eventually succumb to their disease, demonstrating a pressing need
153 ymphocytopenia of A-T patients and routinely succumb to thymic lymphomas with t(12;14) translocation,
154 isplay enhanced sensitivity to endotoxin and succumb to upregulated proinflammatory cytokine producti
156 ent mouse models of CCHFV infection reliably succumb to virus challenge but vary in their ability to
157 ntact adaptive immunity in the periphery but succumb to WNV infection caused by loss of virologic con
158 A ligase IV (Lig4), another key NHEJ factor, succumbed to aggressive lymphoma in the absence of tumor
161 row in the absence of wildtype support cells succumbed to bone marrow failure (median survival, 328 d
166 ently died as a result of lymphoma, but nine succumbed to complications associated with extensive pri
167 mortem lung specimens from four patients who succumbed to COVID-19 and four patients who died from a
170 shock syndrome toxin (TSST-1), Mif(-/-) mice succumbed to death more quickly with increased pulmonary
171 pressing hCD26/DPP4 viral receptor uniformly succumbed to death within 6 days, making it difficult to
172 nfection, only 30% (3/10) of Tbx21(-/-) mice succumbed to disease during the cerebral phase of infect
173 ompromised mice bearing established lymphoma succumbed to disease significantly earlier than tumor be
175 ll suffered severe neurological disease: 60% succumbed to disease, and the survivors experienced long
179 Most homozygous Hbb-b2(Plt12/Plt12) mice succumbed to early lethality associated with emphysema,
180 were collected from 12 rhesus macaques that succumbed to Ebola virus (EBOV) disease from 5 to 8 days
182 axinine E (2) and taxabaccatin III (3), have succumbed to enantioselective total synthesis for the fi
185 ing or lacking PD-1 signaling in CD8 T cells succumbed to fatal CD8 T cell-mediated immunopathology e
190 r rodentium infection, while Nfkb2(-/-) mice succumbed to gut infections owing to stromal defects.
193 Animals became viremic within 4 days and succumbed to infection between 8 and 9 days, and a petec
194 hours and then rapidly decreased as animals succumbed to infection between days 5 and 8 after exposu
195 devoid of T cells failed to control VACV and succumbed to infection despite a marked increase in NK c
196 ntaining Ifnar-deficient hematopoietic cells succumbed to infection early, whereas Ifnar-deficient mi
198 protein of CDV vaccine strain Onderstepoort succumbed to infection with a more recent wild-type stra
199 mally (i.d.) or intranasally (i.n.) with LVS succumbed to infection with doses 2 log units less than
201 iking features were observed in animals that succumbed to infection, including high viral titers in a
202 t terminal stages of disease in animals that succumbed to infection, indicating substantial consumpti
203 ith K3995 exhibited intestinal pathology and succumbed to infection, while none of those infected wit
211 (Ifit2(-/-)) suffered severe weight loss and succumbed to intranasal infection with SeV strain 52 at
214 layed, a small number of suckling mice still succumbed to lethal intracerebral infection with the miR
215 icantly, however, mice lacking TNFR1 in MDCs succumbed to listeria infection, although they displayed
216 s required because most SCID mice eventually succumbed to local tumor recurrence even with combined c
217 Trif(-/-)Cardif(-/-) (MyTrCa(-/-)) mice that succumbed to low-dose i.v. VSV infection with similar ki
221 er, P. berghei ANKA-infected Card9(-/-) mice succumbed to neurological signs and presented with disru
223 d females supplemented with 17beta-estradiol succumbed to P. aeruginosa challenge earlier than proges
225 compared with untreated control animals that succumbed to pneumonia (1.6 x 10 colony forming units/g
236 is of autopsy specimens from 24 patients who succumbed to SARS-CoV-2 infection using a combination of
237 directly damaged by the initial insult, but succumbed to secondary degeneration, remain unclear.
240 pathological samples from 22 individuals who succumbed to SFTS, and identified antibody-producing B c
241 Just several weeks later, when it likely succumbed to starvation in a drought-stressed ecosystem,
242 iously infected with an H3N2 influenza virus succumbed to systemic disease and encephalitis after H5N
245 The data demonstrate that individuals who succumbed to the disease show stronger upregulation of i
250 in response to S. typhimurium infection, and succumbed to the infection 2 days before control mice.
251 and T cells developed clinical symptoms and succumbed to the infection earlier than the wild-type gr
252 ood and tissues and the infected mice either succumbed to the infection within 24 hours or completely
253 st, mice lacking the IFN-alpha/beta receptor succumbed to the infection, with VSV spreading throughou
257 led to mount cross-reactive CD8+ T cells and succumbed to the second challenge with heterologous H3N2
259 ted primary resistance to VEGFRi and quickly succumbed to their diseases within 6 months after the di
263 , but Toll-like receptor 4-deficient animals succumbed to these infections within roughly 1 week.
265 oxB; however, CGNs from STAT1 knock-out mice succumbed to ToxB-induced apoptosis as readily as wild-t
266 e resistance; however, these mice eventually succumbed to toxoplasmic encephalitis, despite the prese
267 ays of composting, only one in five hamsters succumbed to TSE disease, suggesting at least a 4.8 log1
271 ar1(-/-)) developed neurological disease and succumbed to ZIKV infection, whereas single Irf3(-/-), I
272 ce different outcomes, with some individuals succumbing to acute infection while others control the p
274 hyperbilirubinemia, with 8-10% of hUGT1 mice succumbing to CNS damage, a phenotype that is presented
275 of three intracerebrally challenged animals succumbing to disease at 766 d and displaying all of the
276 mplex navigation and decision making without succumbing to distractions and unforeseen obstacles.
279 ays 5 and 6, maintaining a high fever before succumbing to EVD between 6 and 8 days after challenge.
280 Despite the vast majority of individuals succumbing to infection with severe acute respiratory sy
286 e cytosol but also for preventing TRC35 from succumbing to RNF126-mediated ubiquitylation and degrada
287 at several time points prior to the animals succumbing to salmonellosis were like those seen with th
288 largely unexplored despite asplenic patients succumbing to the infection in the first 24 h, suggestin
294 RTD representing a 'penumbra', which slowly succumbs to molecularly governed spatial cellular stoich
296 fected intranasally with pneumococci rapidly succumbed, with 80% mortality after 48 h, whereas the ma
299 w as 10 PFU of SFTSV, with animals generally succumbing within 5 to 6 days after subcutaneous challen