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1 n three independent loci (a further 783 were suggestive).
4 We also identified >60 candidate loci with suggestive association (p < 5 x 10(-5)) and devised a ge
6 designed to score gene haplotypes, we find a suggestive association between carrying multiple missens
9 (p = 8.3 x 10(-9), rs139528938) and showed a suggestive association with Drug Experimentation (p = 3.
10 e on chromosome 16 (P = 3.8 x 10-8) and many suggestive associations (P < 1.0 x 10-5) for each of the
11 9 genes that met criteria for significant or suggestive associations after multiple-testing correctio
13 c, and Brazilian ancestry, with follow-up of suggestive associations in an additional 131,012 individ
15 AN20 and ARGLU1-FAM155A respectively) showed suggestive associations with serum FGF21 level (P = 6.66
16 a), off-label claim + pro forma disclaimers (suggestive but not conclusive evidence for use as an add
18 ffect of ozone on the DNA methylome but some suggestive changes in PLSCR1, HCAR1, and LINC00336 DNA m
19 pect to downstream disease outcomes revealed suggestive differential associations across DM trial arm
20 ting regional variant intolerance identified suggestive dominant signals in CPT2 and several other ca
22 o establish strong evidence (P < 0.0042) and suggestive evidence (0.0042 < P < 0.05) for associations
23 hat BMI causally influences cotinine levels, suggestive evidence for a negative causal influence on N
25 in the overall population, although we found suggestive evidence linking later weekend sleep with ove
26 PRPF3), 2p25.2 (NRIR), 3q22.1 (COL6A6), with suggestive evidence of association (P < 8.5 x 10(-8)) wi
27 HR: 0.79; 95% CI: 0.49, 1.27), but there was suggestive evidence of beneficial treatment effects for
33 ased association testing provided additional suggestive evidence that both WWTR1 and a second gene, L
36 1.10, 95% CI 1.06-1.15; P = 6.94 x 10-7) and suggestive evidence that lifetime smoking exposure was a
37 cted liver cancer TCGA cohort, and uncovered suggestive evidence that tumor neoepitopes actually domi
39 e (Class I), yet 3 outcomes presented highly suggestive evidence, 5 outcomes presented suggestive evi
40 ly suggestive evidence, 5 outcomes presented suggestive evidence, and 37 outcomes presented weak evid
41 mong people living with HIV [PLWHIV]) showed suggestive evidence, with P values < 10-3; only 3 (5.5%;
45 to geography and not host species, which is suggestive for rare transmission events between differen
46 o account all of these metrics, we provide a suggestive guideline for method choice based on availabl
48 ate two loci at 3q13.33 and 3p24.1 that were suggestive in the original GWAS with additional genotypi
50 xponential model, we found three loci with a suggestive linkage to bloodstream infection, all on chro
53 anity (n = 135, 32.7%), sexually explicit or suggestive material (n = 37, 9.0%), name-calling (n = 14
54 oposes that teeth may be an understudied yet suggestive new tool to identify individuals at risk for
56 of whom had two identical intact sequences, suggestive of a cell clone harboring a replication-compe
57 er therapy treatment showed a gene signature suggestive of a change resulting from exposure to a mito
62 e paired-pulse ratio at excitatory synapses, suggestive of a decrease in presynaptic glutamate releas
64 osed EEG signatures of consciousness, and is suggestive of a direct causal effect of tDCS on consciou
66 et neurodegenerative condition with features suggestive of a disordered response to inflammation.
70 XCR3 ligands by airway macrophages, which is suggestive of a feedforward loop of T(H)1 cell recruitme
72 ides and nucleic acids in current biology is suggestive of a functional co-evolution between the two
73 sociated with H3K9me3-marked heterochromatin suggestive of a functional interplay between these two g
78 sitive selection in the African ape lineage, suggestive of a gene undergoing strong adaptive evolutio
79 morphology in patients and their siblings is suggestive of a genetic imaging phenotype, independent o
81 cells also display a transcriptional pattern suggestive of a high basal activation of the Nrf2 transc
82 le genetic structure within the archipelago, suggestive of a high degree of isolation and long-lastin
85 independent of cell swelling, and instead is suggestive of a mechanism by which cells sense changes i
86 mbled that of MALT B cell lymphoma Ig genes, suggestive of a mechanism in which a progressive molecul
87 mpaired microglia physiology and cell death, suggestive of a mechanistic convergence between aging an
88 ts expressed multiple (categorical) factors, suggestive of a mosaic of subtypes within individuals.
90 ple regions within low-complexity sequences, suggestive of a multipartite interface that extends beyo
92 patients induce cytotoxicity in macrophages, suggestive of a pathogenic or inflammatory role in the C
94 y nonlinear current-voltage characteristics, suggestive of a pinned Wigner solid, when [Formula: see
96 atio, similar to previous findings there and suggestive of a previously unknown He isotopic fractiona
97 arly stage was found to be Arf1 independent, suggestive of a previously unreported function of COPI u
98 all core are known to occur, and are further suggestive of a role for MmpL3 in the coordination of ne
99 are reminiscent of sleep slow waves (SW) and suggestive of a role for sleep in brain plasticity that
100 showed no specific trend or pattern that was suggestive of a safety issue in patients receiving osime
101 e SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due
103 art of clusters of TCRs of similar sequence, suggestive of a spatially constrained antigen-driven pro
104 icity and higher enrichment of loop factors, suggestive of a stable primary contact with the promoter
106 nslocation of p65 as mediated through SETD1, suggestive of a synergistic effect between SETD1 and p65
108 ction of the full memory phenotype, which is suggestive of a unique program triggered by recognition
109 en the tested Turkish and Caucasian families suggestive of a variant hotspot region rather than a fou
114 These rAID-1 gene clusters have a structure suggestive of active gene acquisition and include predic
115 ed most among all major immune cell subsets, suggestive of active homing of MAIT cells to the site of
117 de multiple tsaI homologs at the tspA locus, suggestive of additional roles in intraspecies competiti
118 phorylation hotspots for 162 protein domains suggestive of an ancient role for the control of diverse
124 2 is a homodimer that is unable to bind DNA, suggestive of an autoinhibitory mechanism that prevents
127 ctivation, and proliferation were increased, suggestive of an imbalance between the PLCgamma1 and PI3
128 vels of a shorter transcript missing exon 3, suggestive of an incompletely penetrant splice defect.
129 ith Pneumocystis beta-glucan alone, which is suggestive of an inhibitory role for these 2 CLRs in Msg
130 this is linked to differential KZFP binding, suggestive of an ongoing evolutionary arms race between
131 The phenotypic variation observed in PCOS is suggestive of an underlying genetic heterogeneity, but a
132 R patients self-reporting bronchial symptoms suggestive of asthma and 8 healthy controls (HC) were su
133 LAR) patients self-report bronchial symptoms suggestive of asthma, but the relationship between the a
134 gulations resulted in a behavioral phenotype suggestive of autism spectrum disorder in the xCT(-/-) m
137 otein turnover were predominant in the data, suggestive of broad restructuring of the chickpea proteo
138 cardiac magnetic resonance imaging findings suggestive of cardiac amyloidosis, cardiac scintigraphy
142 itive to SRC family kinase (SFK) inhibition, suggestive of channel regulation by tyrosine phosphoryla
146 ction, specifically observed in AD, could be suggestive of compensatory mechanisms to overcome the lo
148 ons between sporadic cases and outbreaks are suggestive of contemporaneous community transmission.
149 ts in the emergency department with symptoms suggestive of COVID-19 infection were studied by using l
154 ity, and males exhibited physiologic changes suggestive of defective AT expandability, including incr
155 Nerve conduction study (NCS) abnormalities suggestive of demyelination are mandatory to fulfil the
159 stering revealed a group of samples that was suggestive of dysbiosis, and LV-Co increased the risk of
161 analysis revealed changes in gene expression suggestive of endoplasmic reticulum (ER) stress in fluor
162 barrier function and a synthetic repertoire suggestive of endothelial-to-mesenchymal transition.
163 e phosphate pathway and (13)C incorporations suggestive of enhanced capacity for the de novo synthesi
164 y induced in soybean at 2 d postinoculation, suggestive of enhanced pathogen virulence on soybean.
165 ed better clinical and radiographic outcomes suggestive of enhanced periodontal regeneration when com
166 ent changes in structure and gene expression suggestive of epithelial-to-mesenchymal transition and t
167 n, with new combinations of protein domains, suggestive of evolutionarily novel aphid-specific functi
169 phalosporin resistance in Enterobacteriaceae suggestive of extended-spectrum beta-lactamase (ESBL) pr
170 olding ultrastructures in individual nuclei, suggestive of extensive dynamic fluidity in 3D chromatin
171 mp repeats containing several internal LTRs, suggestive of extensive recombination during retrotransp
176 ands SLIT3 and NETRIN1 (NTN1) by a mechanism suggestive of H4K20ac removal on promoters and enhancers
178 625) of participants had an OLBI score >=35, suggestive of high levels of burnout, and 16.1% (N=336)
179 sociated with lower RT-PCR cycle thresholds, suggestive of higher upper respiratory tract viral loads
180 first group (G1, n = 50) had a biopsy highly suggestive of humoral rejection, and the second (G2, n =
181 mplicons with specific structural signatures suggestive of hybrid, human-viral extrachromosomal DNA.
182 aneuploidy gene-expression signature that is suggestive of hypo-osmotic stress, using a strategy that
183 , and the frequency of mutational signatures suggestive of immunotherapy resistance is low, pointing
187 s binucleated cells had a functional profile suggestive of increased basal adrenergic activation.
188 Synaptotagmin-2 (Syt2) signals on PV+ cells suggestive of increased inhibitory input between PV+ neu
194 skin biopsy revealed intranuclear inclusions suggestive of intranuclear inclusion body disease (NIID)
195 up of 65 patients with neurological symptoms suggestive of ischaemia in the area of the MCA within 12
196 xpected interaction of cholesterol with CB1, suggestive of its endogenous allosteric modulating role.
197 ant (OR = 1.68 (95%CI 1.07-2.65) p = 0.023), suggestive of its role in iron accumulation in humans.
198 Phylogenetic analysis revealed 3 clusters suggestive of linked transmission; each contained >=1 in
201 demonstrate any immunohistochemical features suggestive of Lynch Syndrome, though the rapid progressi
204 e, and then transferred onto soft hydrogels, suggestive of mechanomemory upstream of paraspeckle regu
205 ith EV-A71 neurological disease had findings suggestive of meningitis, 31 (72%) children showed evide
209 derwent brain MRI, often with an ovoid shape suggestive of microvascular pathology and with a predile
210 lower crystallinity for Co-rich mackinawite, suggestive of mineral-specific bacterial interaction.
212 ng to the emergency department with symptoms suggestive of myocardial infarction may be useful in det
213 ng to the emergency department with symptoms suggestive of myocardial infarction, we determined the c
215 flexia, and electrophysiologic abnormalities suggestive of neuropathy were frequently observed but we
218 patients (controls) with no imaging findings suggestive of pancreatic disease and normal amylase and
220 nologic tests along with radiologic features suggestive of past evidence of tuberculosis infection.
224 eful, noninvasive adjunct to detect features suggestive of PCV, which may prompt definitive investiga
226 high prevalence of mixed L2/L4 profiles was suggestive of polyclonal infection in the region, althou
227 s were categorized as having findings highly suggestive of PPS maculopathy; 25 patients showed some f
228 classified patient images as follows: highly suggestive of PPS maculopathy; some features resembling
229 ed as having normal biomarkers or biomarkers suggestive of primary Alzheimer's disease pathology.
230 ive lesions and then differentiating lesions suggestive of prostate cancer from those that were benig
231 infection can occur but is a rare phenomenon suggestive of protective immunity against reinfection th
232 unequivocally evoking a destructive process suggestive of pulmonary gangrene, a variant of the fract
233 lood vessel density and increased DNA damage suggestive of reactive oxygen species (ROS) activity.
235 n the misregulation of DNA repair machinery, suggestive of reduced DNA repair capacity following UV i
236 the Little Ice Age (700 to 200 years BP) are suggestive of reduced ISM rainfall, whereas lower delta(
237 ased integration of independent data sources suggestive of regulatory interactions produces meaningfu
238 h no evidence of late gadolinium enhancement suggestive of replacement fibrosis or focal necrosis.
239 equal to or above systemic arterial values, suggestive of retrograde capillary blood aspiration, wer
240 describing a different symptom presentation (suggestive of schizophrenia, bipolar, or major depressio
241 eaflets merged into a single peak over time, suggestive of scrambling, and the effect of the channel
242 ficiency of mass transfer to pups increases, suggestive of selective disappearance of poor-quality mo
244 the setting of pandemic COVID-19 was highly suggestive of severe acute respiratory syndrome coronavi
245 mediated by similar physiological responses, suggestive of shared molecular and behavioral pathways i
247 enetic background and risk of early-onset is suggestive of skin barrier dysfunction etiology of AD wi
248 er size-distribution in the lower size range suggestive of some impurities of non-vesicular aggregate
249 with parvalbumin neuropil immunostaining, is suggestive of specialized auditory processing in the tre
250 I demonstrates broad-scale intron retention, suggestive of spliceosome interference, as well as speci
257 RV were obtained, based on ocular phenotypes suggestive of TBU and corroborative evidence of tubercul
258 hildren with food-allergic sensitization are suggestive of TGF-beta-mediated compensation for chronic
259 rtain cardiac imaging findings may be highly suggestive of the diagnosis of Fabry disease in previous
260 ch with no empirical parameters-are strongly suggestive of the existence of an LLT, bolstering the hy
261 d not be linked with known, annotated genes, suggestive of the existence of numerous unidentified gen
264 tensity of the F-coronal intensity, which is suggestive of the long-sought dust free zone(9-11).
265 be altered, especially in eyes with findings suggestive of the pachychoroid spectrum of disorders.
266 ntermediate to an irreversible conformation, suggestive of the postfusion 6-helix bundle; NPC1 bindin
267 eyes with higher corneal SPs and lower CCT, suggestive of thin and stiff corneas, are at greater ris
268 onectin, collagen 1A, vimentin, and laminin, suggestive of transition to a mesenchyme-like phenotype.
271 ent of DNA methyltransferases in gametes and suggestive of unexplored regulatory activities of gamete
273 valuated between 2011 and 2017 with findings suggestive of vascular loops in the cerebellopontine ang
274 relations between guild abundances per plot, suggestive of weak signals of both inter-guild competiti
275 e pattern to anti-PD1 therapy in cHL that is suggestive of withdrawal of prosurvival factors, rather
276 No individual CNV achieved thresholds for suggestive or significant association after genome-wide
281 cases with APOL1 risk genotypes identified a suggestive signal in AHDC1, implicated in Xia-Gibbs synd
283 itability of this phenotype, have identified suggestive signals, and evaluated the association betwee
284 0(-8)), while five of the 21 lead SNPs reach suggestive significance (P < 1 x 10(-5)) for at least on
285 Seven additional loci were identified at suggestive significance (P < 10(-6)): 1q31, 5q23, 6q15,
287 0.15 to 0.81)) and greater responsiveness to suggestive symptom induction (SMD, 1.39 (95% CI 0.92 to
288 ity using standardised behavioural scales or suggestive symptom induction protocols in patients with
289 s in which children hold others accountable, suggestive that children's evaluations of moral and epis
290 ive pressure at this region of the molecule, suggestive that functional constraints prevent immune-dr
293 o be a general feature of cells in diapause, suggestive that this may be a mechanism to halt the grow
294 (LPS) within Chlamydia inclusions, which is suggestive that TLR3 deficiency leads to enhanced chlamy
299 gion-based association tests identified four suggestive windows that harbored candidate rare variants