戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1  that catalyzes the formation of the heparan sulfate chain.
2 eavy chains (HC1 and HC2) on its chondroitin sulfate chain.
3 n one or more heparan sulfate or chondroitin sulfate chains.
4 can present in other tissues without keratan sulfate chains.
5 n bearing chondroitin sulfate and/or heparan sulfate chains.
6 ble of carrying both heparan and chondroitin sulfate chains.
7 f the poorly sulfated domains in its heparin sulfate chains.
8 e the different populations of short heparan sulfate chains.
9 se activity related to elongation of heparan sulfate chains.
10 vitro, an activity that requires chondroitin sulfate chains.
11 an core protein after the removal of keratan sulfate chains.
12  in many non-corneal tissues without keratan sulfate chains.
13 MR106 cells was substituted with chondroitin sulfate chains.
14 o in the length and sulfation of its keratan sulfate chains.
15  substitution of these proteins with keratan sulfate chains.
16 can found to contain large, sulfated keratan sulfate chains.
17 to the initiation and termination of heparan sulfate chains.
18 ain and the extended conformation of heparan sulfate chains.
19 ane, where TG2 also colocalized with heparan sulfate chains.
20 itin in addition to low-sulfated chondroitin sulfate chains.
21 nctional differences in the attached heparan sulfate chains.
22 ies on both its core protein and its heparan sulfate chains.
23 y influencing total sulfation of the heparan sulfate chains.
24 iable number of attachment sites for heparan sulfate chains.
25 odified with chondroitin sulfate and heparan sulfate chains.
26  chains (CS) and normal sulfation of heparan sulfate chains.
27  removal or reduction in the size of heparan sulfate chains.
28  is affected by 6-O-sulfation of the heparan sulfate chains.
29 d for the addition of sulfate to the heparin sulfate chains.
30  Th2 cells in the lung through their heparan sulfate chains.
31 glycosyltransferases that synthesize heparan sulfate chains.
32 has been attributed largely to their heparan sulfate chains.
33 o proteoglycans is mediated by their heparan sulfate chains.
34 due to structural differences of the heparan sulfate chains.
35 uctures or after enzyme digestion of heparan sulfate chains, a distinct network with a diffuse electr
36 n of N-syndecan that was modified by heparan sulfate chain addition.
37 how the pattern of sulfation along a heparan sulfate chain affects its turnover, we examined heparan
38 ccharides alone or with a single chondroitin sulfate chain alone; however, there is severely impaired
39 glycan substituted with a single chondroitin sulfate chain and N-linked oligosaccharides and a core p
40             Binding involves the chondroitin sulfate chains and a specific site on the first immunogl
41               Because syndecan-1 has heparan sulfate chains and because exogenous heparan sulfate has
42 ractions between LPL and SDC1-linked heparan sulfate chains and between LPL and the Golgi membrane.
43 athepsin L is independent of its chondroitin sulfate chains and is effective at both pH 5.5 and 7.2.
44 genesis only requires the syndecan-1 heparan sulfate chains and not the intact ectodomain, suggesting
45 e known KSPG proteins, modified with keratan sulfate chains and sulfated on both N-acetylglucosamine
46 ecan-1 to uropods is mediated by its heparan sulfate chains and that targeting is regulated by cell s
47 ase involved in the synthesis of chondroitin sulfate chains and the receptor for PDGFbeta, a growth f
48 long with its glycosaminoglycan (chondroitin sulfate) chains and particularly 6-O-sulfated species.
49 microg/ml), enzymatic removal of the heparan sulfate chains, and by chlorate inhibition of glypican s
50  LON-2/glypican protein, lacking its heparan sulfate chains, and secreted forms of LON-2/glypican are
51 re considerably smaller than the chondroitin sulfate chains, and the heparan sulfate disaccharide con
52 and intracellular trafficking of the heparan sulfate chains appeared normal, and the chains degraded
53 ng is dramatically enhanced when the heparan sulfate chains are enzymatically degraded or absent from
54                                 The dermatan sulfate chains are known to stimulate thrombin inhibitio
55              However, when all three heparan sulfate chains are present, significantly greater biolog
56 m chlorate, indicating that sulfated heparan sulfate chains are required for nuclear translocation.
57   These results suggest that soluble heparan sulfate chains, as products of the degradation of hepara
58 encode the copolymerase required for heparan sulfate chain assembly.
59 ith heparanase action by binding the heparan sulfate chain at a sequence next to the cleavage site or
60 CR4 is efficiently modified by a chondroitin sulfate chain at serine 18, but neither HIV-1 entry nor
61 ntaining the central domain have chondroitin sulfate chains attached to the protein core.
62                  Silencing lymphatic heparan sulfate chain biosynthesis inhibited VEGF-C-mediated Erk
63 nvasion is dependent on the syndecan heparan sulfate chains, but a role for the syndecan-1 ectodomain
64 protein requires the presence of the heparan sulfate chains, but the interaction appears to be relati
65 d at the reducing termini of the chondroitin sulfate chains by digestion with chondroitin ABC lyase,
66                CD44 isoforms bearing heparin sulfate chains can bind to HGF/SF and facilitate its pre
67 eta)(S3L), is composed of sialylated keratan sulfate chains carried on a minor isoform/glycoform of R
68  regulation of expression of two key heparan sulfate chain-carrying core proteins, syndecan-1 and syn
69 h VI and to correlate activity with dermatan sulfate chain composition and structure.
70             Conversely, chondroitin/dermatan sulfate chain concentrations were increased by 60-70% in
71                                      Keratan sulfate chain concentrations were reduced by approximate
72                               Intact keratan sulfate chains derived from bovine tracheal cartilage ha
73                The results show that heparan sulfate chains differ between various members of the pro
74 which remove 6-O sulfate groups from heparan sulfate chains, diminishes myeloma tumor growth in vivo.
75 f DMBT1 carrying O-linked sialylated keratan sulfate chains (DMBT1(S8)).
76 arinase III, an enzyme that degrades heparan sulfate chains, dramatically inhibited the growth of pri
77 er investigated the role of EXTL2 in heparan sulfate chain elongation by gene silencing and overexpre
78  in more detail the role of EXTL2 in heparan sulfate chain elongation, we tested the ability of the o
79 rmore, our data suggest that the chondroitin sulfate chain engenders APP with novel biological functi
80  estrogen, both perlecan protein and heparan sulfate chain expression markedly increase.
81 ce, and a mutated syndecan-1 lacking heparan sulfate chains fails to concentrate within uropods.
82         The sulfation pattern of the heparan sulfate chains formed during biosynthesis in the Golgi c
83                     Chondroitin and dermatan sulfate chains from arthritic cartilages were of essenti
84 owever, enzymatic removal of the chondroitin sulfate chains from biglycan proteoglycan does not induc
85 y purified activities from releasing heparan sulfate chains from core proteins and degrading them to
86  sulfate structure, we have analyzed heparan sulfate chains from the different surface proteoglycans
87                         Instead, the heparan sulfate chains from the mutant were relatively resistant
88            The newly synthesized chondroitin sulfate chains had a similar composition to the endogeno
89                                  The heparan sulfate chains (HS) mediate stable high affinity binding
90  with the cell surface through their heparan sulfate chains (HS), but it is not known if they are oth
91  Interestingly, cargo bound to sSDC1 heparan sulfate chains (i.e. hepatocyte growth factor) was trans
92  modification of keratocan with long keratan sulfate chains in cornea, suggests that this molecule ma
93 ance between chondroitin sulfate and heparan sulfate chains in dictating ligand responses with implic
94      In conclusion, the lack of Sdc4 heparan sulfate chains in the kidneys of Sdc4-null mice abrogate
95  from mutant cells cleaved wild-type heparan sulfate chains in vitro.
96 lent cations in concert with the chondroitin sulfate chain influence the structure and stability of i
97               The negatively charged heparan sulfate chains interact with a multitude of different pr
98                              The chondroitin sulfate chain interacted with all protein components and
99 ction or amount of syndecan-1 or its heparan sulfate chains is a valid therapeutic approach for this
100 d show that overall sulfation of the heparan sulfate chains is more important than sulfation at parti
101 (heparanase), an enzyme that cleaves heparan sulfate chains, is expressed at high levels in some pati
102 es elongation resulting in increased heparan sulfate chain length.
103 cell line had little or no effect on heparan sulfate chain length.
104 mechanism requiring sulfation of chondroitin sulfate chains linked to CD44.
105                         Cell surface heparan sulfate chains linked to glypican-1 (GPC1) capture FGF2
106 lycopeptide containing two different heparan sulfate chains, namely the extracellular domain of synde
107          This labeled KSPG contained keratan sulfate chains of 4700 Da compared to 21,000 Da for bovi
108 sulfate groups to be enriched in the heparan sulfate chains of GPC1 to which FGF2 binds with high aff
109 nal antibody primarily targeting the heparin sulfate chains of GPC3 inhibited Wnt/beta-catenin signal
110  which preferentially recognized the heparan sulfate chains of GPC3, both the sulfated and nonsulfate
111 nfers atheroprotection by binding to heparan sulfate chains of heparan-sulfate proteoglycan 2 (HSPG2)
112 g modification of the proteins with dermatan sulfate chains of increased sulfation.
113 glycan form substituted with two chondroitin sulfate chains of molecular mass approximately 34 kDa (H
114  proteins actually interact with the heparan sulfate chains of one or more membrane or extracellular
115 nding, suggesting the involvement of heparan sulfate chains of proteoglycan in the interaction.
116 idase that specifically degrades the heparan sulfate chains of proteoglycan, a component of blood ves
117 Heparanase is an enzyme that cleaves heparan sulfate chains of proteoglycans, and its expression has
118 paranase, an enzyme that cleaves the heparan sulfate chains of proteoglycans, is upregulated in a var
119               We discovered that the heparan sulfate chains of syndecan-1 captured VEGF and also atta
120 iated by the binding of gp120 to the heparan sulfate chains of syndecan.
121 od cells and binds to specific chondroitin-4-sulfate chains of the placental proteoglycan receptor.
122 aminoglycans (GAGs), such as the chondroitin sulfate chains of the proteoglycan versican, have been s
123 bronectin, which are ligands for the heparan sulfate chains of the proteoglycan.
124 r the cell surface CSF-1 and the chondroitin sulfate chain on secreted proteoglycan CSF-1 during rena
125 f viral glycoproteins gB and gC with heparan sulfate chains on cell surface proteoglycans.
126                                  The heparan sulfate chains on growth plate perlecan were considerabl
127                              The chondroitin sulfate chains on neurocan and phosphacan account for at
128 d bikunin covalently joined by a chondroitin sulfate chain originating at Ser-10 of bikunin.
129 uronic acid, keratan sulfate, or chondroitin sulfate chains over the concentration range studied.
130 ndicate that O-sulfate groups on the heparan sulfate chains play a critical role in heparin interacti
131 or the GDF-8 prodomain is likely the heparan sulfate chain present on perlecan domain V.
132          We have discovered that the heparan sulfate chains present on syndecan core proteins suppres
133  for this process by analyzing short heparan sulfate chains produced in vivo by Chinese hamster ovary
134  Wnt interactions with the TbetaRIII heparan sulfate chains result in inhibition of Wnt signaling, li
135  nonreducing termini of aggrecan chondroitin sulfate chains revealed important changes in chain termi
136 cetate increases the size of the chondroitin sulfate chain(s) attached to CD44 but not the proportion
137           Structural analysis of the heparan sulfate chains showed that 3-OST-1 generates sequences c
138 l brain endothelial cell HSPGs carry heparan sulfate chains similarly capable of forming a ternary co
139                                      Keratan sulfate chain size was reduced to 3-4 disaccharides; cha
140                         Chondroitin/dermatan sulfate chain sizes were also decreased in all diseased
141 ity for endothelial-derived perlecan heparan sulfate chains than serglycin GAG chains.
142                   In addition to its heparan sulfate chains, the core protein of syndecan-1 was also
143 ese findings assign new functions to heparan sulfate chains, thereby broadening our understanding of
144              The contribution of chondroitin sulfate chains to the binding of neurocan and phosphacan
145 V-1 entry depends on (1) presence of heparan sulfate chains to which virus can bind and (2) 3-O-sulfa
146 ; the presence of fully digested chondroitin sulfate chains was established.
147 ture, the amount of perlecan bearing heparan sulfate chains was unaffected by TGF-beta1 and decreased
148   The levels of perlecan bearing chondroitin sulfate chains were elevated with TGF-beta1 treatment an
149 ted syndecans having two, one, or no heparan sulfate chains were expressed in ARH-77 cells.
150 omponent of this network whereas its heparan sulfate chains were integrated into the collagen IV-cont
151         Alkaline borohydride-reduced keratan sulfate chains were isolated from human articular cartil
152                                Short heparan sulfate chains were purified from CHO cells and labeled
153 -1080 cells was substituted with chondroitin sulfate chains, whereas about 50% of the biglycan expres
154 amily, are coupled to the N-terminal heparan sulfate chains, which augment high affinity binding and
155 glycan form substituted with two chondroitin sulfate chains with a median molecular mass approximatel
156                 These proteins bear dermatan sulfate chains with increased sulfation compared with no
157 ans was examined by treating the [3H]heparan sulfate chains with nitrous acid or bacterial heparin ly
158 id bilayer, proteoglycan dimers, and heparan sulfate chains with realistic sequences.
159 ional changes induced by heparin and heparan sulfate chains within the extracellular matrix.

 
Page Top