ライフサイエンスコーパス: sulfhydryl oxidase

1 recently discovered enigmatic flavin-linked sulfhydryl oxidase.

2 h protein disulfide bonds in thioredoxin and sulfhydryl oxidase.

3 ases and is related to the ERV/ALR family of sulfhydryl oxidases.

4 on to the earlier reports of metal-dependent sulfhydryl oxidases.

5 , PRDX4, and the candidate oxidants quiescin-sulfhydryl oxidase 1 (QSOX1) and vitamin K epoxide reduc

6 sion (SAGE) databases was enzyme quiescin Q6 sulfhydryl oxidase 1 (QSOX1).

7 on in the 5' untranslated region of quiescin sulfhydryl oxidase 1 isoform a (QSOX1-a), not present in

8 ing that the C-X-X-C motif was essential for sulfhydryl oxidase activity and responsible for the alte

9 lly, the assay is used to show that there is sulfhydryl oxidase activity in a number of secretory flu

10 ted from chicken egg white and found to have sulfhydryl oxidase activity with a range of small molecu

11 92 C(155)XXC(158) amino acids, important for sulfhydryl oxidase activity, were mutated to A(155)XXA(1

12 ns no detectable FAD, and shows undetectable sulfhydryl oxidase activity.

13 n excellent substrate of the enzyme quiescin-sulfhydryl oxidase and may find utility in the character

14 These data show that sulfhydryl oxidase and protein disulfide isomerase can c

15 ells, the assay could detect 15fmol of avian sulfhydryl oxidase and the rates were linearly dependent

16 family of flavin adenine dinucleotide-linked sulfhydryl oxidases and is related to the ERV/ALR family

17 luble 62 kDa FAD-linked and EDTA-insensitive sulfhydryl oxidase apparently constitutes the dominant d

18 revealed GFER, a mitochondrial FAD-dependent sulfhydryl oxidase, as an essential regulator of tumor g

19 The sulfhydryl oxidase augmenter of liver regeneration (ALR)

20 ysteine and selenomethionine residues in the sulfhydryl oxidase augmenter of liver regeneration (ALR)

21 and depend on the oxidoreductase Mia40, the sulfhydryl oxidase augmenter of liver regeneration (ALR)

22 he cysteine residues are rapidly oxidized by sulfhydryl oxidase, but activity is efficiently restored

23 Sulfhydryl oxidase can also oxidize reduced protein disu

24 sitive, continuous fluorescence assay of the sulfhydryl oxidases can be devised with careful selectio

25 Metal- and flavin-dependent sulfhydryl oxidases catalyze the generation of disulfide

26 Both metal and flavin-dependent sulfhydryl oxidases catalyze the net generation of disul

27 Both metalloprotein and flavin-linked sulfhydryl oxidases catalyze the oxidation of thiols to

28 lfide bond formation in partnership with the sulfhydryl oxidase Ero1 in vitro with higher turnover ra

29 ial flavin adenine dinucleotide (FAD)-linked sulfhydryl oxidase Erv1 (essential for respiration and v

30 Reoxidation of Mia40 is facilitated by the sulfhydryl oxidase Erv1 and the respiratory chain.

31 additional proteins that interacted with the sulfhydryl oxidase Erv1 of the MIA pathway.

32 The sulfhydryl oxidase Erv1 partners with the oxidoreductase

33 ctions involving disulfide transfer from the sulfhydryl oxidase Erv1 to Mia40 and from Mia40 to subst

34 us pathway with the oxidoreductase Mia40 and sulfhydryl oxidase Erv1, termed the mitochondrial interm

35 t that Tim17 can be directly oxidized by the sulfhydryl oxidase Erv1.

36 hen in excess or at a lower rate by only the sulfhydryl oxidase Erv1.

37 In contrast, the flavin-linked sulfhydryl oxidase from Aspergillus niger is related to

38 The flavin-dependent sulfhydryl oxidase from chicken egg white catalyzes the

39 The flavin-dependent sulfhydryl oxidase from chicken egg white catalyzes the

40 These metazoan sulfhydryl oxidases have four recognizable domains: a re

41 t biochemical evidence that a plant quiescin sulfhydryl oxidase homolog (QSOX1) is a redox sensor tha

42 A physiological role for sulfhydryl oxidase in the formation of disulfide bonds i

43 Erv1 is a flavin-dependent sulfhydryl oxidase in the mitochondrial intermembrane sp

44 AD prosthetic group of the ERV/ALR family of sulfhydryl oxidases is housed at the mouth of a 4-helix

45 reinvestigation of the metal content of skin sulfhydryl oxidases is warranted.

46 oth the egg white enzyme and a flavin-linked sulfhydryl oxidase isolated from bovine semen.

47 Two of these (quiescin-sulfhydryl oxidase-like and adenosine 5'-phosphosulfate

48 Glucose oxidase, hexose oxidase, peroxidase, sulfhydryl oxidase, lipase, and lipoxygenase form disulf

49 s enzymes (tyrosinase, peroxidase, catalase, sulfhydryl oxidase, lipoxygenase, lipase, protein disulf

50 with the augmenter of liver regeneration, a sulfhydryl oxidase of the mitochondrial intermembrane sp

51 ies between members of the ERV/ALR family of sulfhydryl oxidases provides insights into their likely

52 Flavoproteins of the quiescin/sulfhydryl oxidase (QSOX) family catalyze oxidation of p

53 es the substrate specificity of the quiescin sulfhydryl oxidase (QSOX) family of disulfide-generating

54 The quiescin sulfhydryl oxidase (QSOX) family of enzymes generates di

55 ge) showed it to be a member of the Quiescin-sulfhydryl oxidase (QSOX) family.

56 Quiescin sulfhydryl oxidase (QSOX) flavoenzymes catalyze the dire

57 in sequence shows it belongs to the Quiescin/sulfhydryl oxidase (QSOX) flavoprotein family.

58 The flavin-dependent quiescin-sulfhydryl oxidase (QSOX) inserts disulfide bridges into

59 The flavoprotein quiescin-sulfhydryl oxidase (QSOX) rapidly inserts disulfide bond

60 tein containing the ERV/ALR domain, quiescin-sulfhydryl oxidase (QSOX).

61 ously linked to cancer, most strongly on the sulfhydryl oxidase Qsox1 which we show is required for m

62 Flavin-dependent sulfhydryl oxidases represent a newly discovered family

63 neration (ALR) is both a growth factor and a sulfhydryl oxidase that binds FAD in an unusual helix-ri

64 Erv2p is a small, dimeric FAD-dependent sulfhydryl oxidase that generates disulfide bonds in the

65 1-like (Gfer) is an evolutionarily conserved sulfhydryl oxidase that is enriched in embryonic and adu

66 ngs to the ERV1/ALR family of FAD-containing sulfhydryl oxidases that use oxygen as the electron acce

67 wn to be a substrate of the flavin-dependent sulfhydryl oxidases, there is little quantitative inform

68 The first mammalian sulfhydryl oxidase to be described was an iron-dependent

69 Chicken egg white sulfhydryl oxidase utilizes an internal redox-active cys

70 understood flavoenzyme may not function as a sulfhydryl oxidase within the mitochondrial intermembran