ライフサイエンスコーパス: sulfonation

1 nd C(537) are involved in OONO(-)-mediated S-sulfonation.

2 ration during subsequent sample handling and sulfonation.

3 for the potential agents responsible for the sulfonation.

4 n may also be catalytically important in the sulfonation.

5 tal and oxidant-free tosylhydrazine-mediated sulfonation.

6 ctivation, culminating in successful methane sulfonation.

7 tropisomeric axis that is introduced through sulfonation.

8 aries are greatly dependent on the degree of sulfonation.

9 rol: The title reaction is effective for the sulfonation and alkylation of arenes bearing directing g

10 expressionof C53A DJ-1 enhanced both Cys-106 sulfonation and cell death.

11 ferase (EST), the enzyme responsible for the sulfonation and inactivation of estrogens, plays an impo

12 S-Sulfonation and S-cysteinylation are prevalent TTR modif

13 ted by the PAH-TPs, including carboxylation, sulfonation and up to three hydroxylation reactions.

14 teinylation, glycosylation, fragmentation, S-sulfonation, and 3-chlorotyrosine formation.

15 tion, formylation, carboxylation, nitration, sulfonation, and others are discussed in detail, particu

16 O2 also induce cell death, with DJ-1 Cys-106 sulfonation appearing causal in these events, as express

17 y important PTMs such as phosphorylation and sulfonation, are difficult to multiply charge in positiv

18 To our knowledge, sulfonation as a therapeutic means of regulating transmi

19 ined with another derivatization, N-terminal sulfonation, as evidenced by tandem mass spectrometry (M

20 ignatures of PTMs such as phosphorylation or sulfonation can be derived.

21 Upon sulfonation, carcinogenic hydroxyarylamines such as N-hy

22 Sulfonation conditions were developed for several BODIPY

23 subjected to regioselective deprotection and sulfonation conditions, which were optimized with the ai

24 Co-derivatization with N-terminal sulfonation confirmed the identity of low-abundance prot

25 Sulfonation controls the affinities of ligands for their

26 a 3D-interconnected nanoporosity and varying sulfonation degrees.

27 (410-427) and to evaluate the requirement of sulfonation for effective thrombin interaction.

28 vation, doping of heteroatoms, halogenation, sulfonation, grafting, polymer coating, noncovalent func

29 dditional information obtained by N-terminal sulfonation in combination with IRMPD provided significa

30 o be possible to accurately predict Phase II sulfonation in silico.

31 method is complementary to classical aniline sulfonation in terms of the variously substituted regioi

32 DJ-1 Cys-106 hyperoxidation (sulfination or sulfonation) in myocytes, perfused heart, or HEK cells.

33 method for localizing peptide and protein O-sulfonation involves derivatization of nonsulfonated tyr

34 While sulfonation is a ubiquitous biochemical modification, th

35 Sulfonation is an important pathway in the biotransforma

36 Sulfonation is prized for its ability to impart water-so

37 lowing steps: chemical N-deacetylation and N-sulfonation leading to N-sulfoheparosan (-GlcA(1,4)GlcNS

38 S(1,4)GlcNS6S-); and selective enzymatic 3-O-sulfonation leading to the anticoagulant heparin, contai

39 heparin (-IdoA2S(1,4)GlcNS-); enzymatic 6-O-sulfonation leading to the heparin backbone (-IdoA2S(1,4

40 nditions where 5mC is resistant to analogous sulfonation leading to thymine (T).

41 ); enzyme-catalyzed C5-epimerization and 2-O-sulfonation leading to undersulfated heparin (-IdoA2S(1,

42 gions that are modified by epimerization and sulfonation (NS domains) are interspersed by unmodified

43 ansferase (PST) preferentially catalyzes the sulfonation of "simple" planar phenols, and levels of ac

44 Sulfonation of 5 and 6 with concentrated sulfuric acid a

45 ere prepared as the tetrasodium salts by the sulfonation of 5,10,15, 20-tetraphenyl-21,23-dithiaporph

46 selective ion-exchange membranes prepared by sulfonation of a spirobifluorene-based microporous polym

47 We report on the synthesis and postsynthetic sulfonation of an aromatic framework (SPAF-2) with a 3D-

48 of reference standards, obtained through the sulfonation of an industrial mixture of PCBs.

49 ndrosterone sulfotransferase (Std) catalyzes sulfonation of androgenic steroids and certain aromatic

50 The human SULTs catalyzed the sulfonation of benzo[a]pyrene-7,8-catechol and generated

51 Sulfotransferase sulfonation of beta-hydroxy-acyl-ACP is followed by TE h

52 o quantitatively convert C to uracil (U) via sulfonation of denatured, single-stranded gDNA under con

53 otein ubiquitination based on the N-terminal sulfonation of diglycine branched peptides.

54 The 3-O-sulfonation of glucosamine residues in heparan sulfate (

55 Sulfonation of graphitic carbon nitride (g-CN) affords a

56 mily that contains enzymes that catalyze the sulfonation of hydrophobic drugs and hormones.

57 transferase is primarily responsible for the sulfonation of N-OH-2AAF in rat liver.

58 o-1H-indol-3-yl)methanone (3), followed by N-sulfonation of one indole moiety to furnish 6-bromo-3-(6

59 We investigated whether sulfonation of PAH catechols by human sulfotransferases

60 Different degrees of sulfonation of polyphenylenesulfone (PPSU) were adopted

61 Moreover, a selective ST-mediated sulfonation of the (R)-beta-hydroxyl group was found to

62 TAM adducts are primarily formed via sulfonation of the alpha-hydroxylated TAM metabolites.

63 Androgen inactivation via sulfonation of the hormone by dehydroepiandrosterone sul

64 ty due to mutation or prior oxidation (e.g., sulfonation) of the critical cysteine thiol, could thus

65 onal group modifications to generate varying sulfonation patterns.

66 It has been established that the degree of sulfonation plays a role in both creating a macrovoid-fr

67 -5 '-phosphosulfate, the cosubstrate for the sulfonation reaction.

68 y phases are selectively crosslinked through sulfonation reactions and subsequently converted to carb

69 The sulfonation reagent Alexa Fluor 350 (AF350) provided the

70 s controlled by the sulfonation time and the sulfonation solution composition and can be as high as 3

71 We present a simple, remote sulfonation solution to BODIPY photocages that imparts w

72 We determined that S-sulfonation stabilized TTR tetramer stability by a facto

73 Upon sulfonation, SULT2A1 substrates become polar and water-s

74 Following sulfonation, the capillaries were coated with 65-nm-diam

75 n of the water dip varies with the degree of sulfonation; the elution order is normal (water dip appe

76 ation exchange capacity is controlled by the sulfonation time and the sulfonation solution compositio

77 , we find that applying the conventional 2,6-sulfonation to meso-methyl BODIPY photocages is incompat

78 orene unit allows control over the degree of sulfonation to optimize the transport of cations, whilst

79 on to lower the p K(a) by 2 units to 5.2 and sulfonation to prevent cyclization to the nonabsorbing f

80 polymerization of native tannins followed by sulfonation via reaction with sulfur dioxide.

81 Chemical derivatization by N-terminal sulfonation was carried out on several model peptides fo

82 De(acetylation), glucosylation and sulfonation were the main metabolic pathways activated.

83 mmodate sites of phosphorylation in place of sulfonation without sacrificing binding affinity.

84 Increasing alkylation reduced the sulfonation yield, instead causing oligomerization side

85 mbranes through carboxylation and subsequent sulfonation, yielding AEA-COOH-AMS membranes with both w