ライフサイエンスコーパス: sulfoxide reductase

1 -sulfoxide reductase) and MsrB (methionine-R-sulfoxide reductase).

2 ide reductase, peroxiredoxin, and methionine sulfoxide reductase.

3 rsed by coexpression with peptide methionine sulfoxide reductase.

4 d by a ubiquitous enzyme, peptide methionine sulfoxide reductase.

5 cular alkenal reductase PTGR1 and methionine sulfoxide reductase.

6 ter solute-binding protein, and a methionine sulfoxide reductase.

7 ersed by treating the enzyme with methionine sulfoxide reductase.

8 idized protein was incubated with methionine sulfoxide reductase.

9 f stereospecific enzymes known as methionine sulfoxide reductases.

10 that are catalyzed by endogenous methionine sulfoxide reductases.

11 of glutathione peroxidase 1 and methionine-R-sulfoxide reductase 1 in the liver, suggesting partial s

12 xidase, ascorbate peroxidase, and methionine sulfoxide reductase 2) are slightly up-regulated.

13 KII inhibition, overexpression of methionine sulfoxide reductase A (an enzyme that reduces oxidized C

14 Methionine sulfoxide reductase A (MsrA) catalyzes the reduction of

15 The enzyme peptide methionine sulfoxide reductase A (MSRA) catalyzes the repair of oxi

16 ing rate, egg mass, expression of methionine sulfoxide reductase A (MSRA) gene, and antioxidant capac

17 Methionine sulfoxide reductase A (MsrA) is an antioxidant repair en

18 Methionine sulfoxide reductase A (MsrA) is an enzyme involved in re

19 Methionine sulfoxide reductase A (MsrA) maintains the function of m

20 xpressed methionine repair enzyme methionine sulfoxide reductase A (MsrA) on the metabolic benefits o

21 Methionine sulfoxide reductase A (MsrA) repairs oxidized methionine

22 ant form of M. genitalium lacking methionine sulfoxide reductase A (MsrA), an antioxidant enzyme whic

23 CaMKII oxidation is reversed by methionine sulfoxide reductase A (MsrA), and MsrA-/- mice show exag

24 Here, we report that methionine sulfoxide reductase A (MSRA), which can reduce oxidized

25 be reversed through the action of methionine sulfoxide reductase A (MsrA), which is implicated in oxi

26 in (NT domain) is fused to tandem methionine sulfoxide reductase A and B domains (MsrA/B).

27 strate almost absent catalase and methionine sulfoxide reductase A and B protein expression via immun

28 ) method for the determination of methionine sulfoxide reductase A and methionine sulfoxide reductase

29 Methionine sulfoxide reductase A is an essential enzyme in the anti

30 Methionine sulfoxide reductase A is an essential enzyme in the anti

31 Lipidation of methionine sulfoxide reductase A occurs in the mouse, in transfecte

32 led the redox relay mechanisms of methionine sulfoxide reductase A of the pathogen Corynebacterium di

33 uctase, glutathione reductase and methionine sulfoxide reductase A proteins were significantly up-reg

34 of only glutathione reductase and methionine sulfoxide reductase A proteins were significantly up-reg

35 ling by targeting the antioxidant methionine sulfoxide reductase A to modulate liposarcoma cell survi

36 in vivo binding partner of MSRA (methionine sulfoxide reductase A), an enzyme that reduces methionin

37 cted transgenic overexpression of methionine sulfoxide reductase A, an enzyme that reduces oxidized C

38 oxide dismutase (SOD2), catalase, methionine sulfoxide reductase A, and the 20S proteasome subunits P

39 ues of diverse targets, including methionine sulfoxide reductase A, myosin light chain kinase, and Ru

40 er-expression of a repair enzyme, methionine sulfoxide reductase A, rendered them resistant, suggesti

41 ylated and nonmyristoylated mouse methionine sulfoxide reductase A.

42 idues in proteins is catalyzed by methionine sulfoxide reductases A (MSRA) and B (MSRB), which act in

43 In normal healthy human skin, methionine sulfoxide reductases A and B specifically reduce methion

44 epaired in the human epidermis by methionine sulfoxide reductases A and B, respectively.

45 MSRAs (methionine sulfoxide reductases A) are enzymes that reverse the eff

46 activation of HypT depends on the methionine sulfoxide reductases A/B.

47 ional selenoproteins, including methionine-S-sulfoxide reductase, a selenoprotein specific to Chlamyd

48 iform selenium deficiency because methionine sulfoxide reductase activities were similar in mice and

49 cleus and exhibited the highest methionine-R-sulfoxide reductase activity because of the presence of

50 y, the soluble 83-kDa enzyme retained biotin sulfoxide reductase activity using reduced methyl violog

51 ) were essential for MoCo-dependent dimethyl sulfoxide reductase activity, suggesting that these prot

52 reduced pyridine nucleotide-dependent biotin sulfoxide reductase activity.

53 ia coli and the electron acceptor methionine sulfoxide reductase, also from E. coli, strongly hinted

54 Besides, higher expression of methionine sulfoxide reductase and cysteine peroxiredoxin genes, co

55 nsible for this function: MsrA (methionine-S-sulfoxide reductase) and MsrB (methionine-R-sulfoxide re

56 e reductase, Rhodobacter capsulatus dimethyl sulfoxide reductase, and Shewanella massilia trimethylam

57 Methionine sulfoxide reductases are conserved enzymes that reduce o

58 Peptide methionine sulfoxide reductases are conserved enzymes that reduce o

59 Methionine sulfoxide reductases are key enzymes that repair oxidati

60 Methionine-sulfoxide reductases are unique, in that their ability t

61 hionine sulfoxide reductase A and methionine sulfoxide reductase B activities in mouse liver is descr

62 SRA, STARD3 binds all three MSRB (methionine sulfoxide reductase B), enzymes that reduce methionine-R

63 f inactivated GroEL by the enzyme methionine sulfoxide reductase B/A (MsrB/A).

64 onjunction with Mical proteins, methionine-R-sulfoxide reductase B1 (MsrB1) regulates mammalian actin

65 We further expressed mouse methionine sulfoxide reductase B1 (MsrB1), a selenoenzyme that cata

66 nd that a cytosolic pool of human methionine sulfoxide reductase B2 (MsrB2) is strongly recruited at

67 lamine-N-oxide reductase (TMAOR), and biotin sulfoxide reductase (BSOR) are members of a class of bac

68 cter sphaeroides f. sp. denitrificans biotin sulfoxide reductase (BSOR) catalyzes the reduction of d-

69 Rhodobacter sphaeroides biotin sulfoxide reductase (BSOR) contains the bis(molybdopteri

70 pecies resembled not only a related dimethyl sulfoxide reductase but also a structurally unrelated ni

71 d that expression of yeast free methionine-R-sulfoxide reductase can fully compensate for this defici

72 to methionine sulfoxide, and the methionine sulfoxide reductases catalyze their reduction back to me

73 cter sphaeroides f. sp. denitrificans biotin sulfoxide reductase catalyzes the reduction of d-biotin

74 The enzymatic activity of the methionine sulfoxide reductase DmsABC helps Salmonella maintain an

75 Enzymes of the dimethyl sulfoxide reductase (DMSOR) family catalyse two-electron

76 Mononuclear molybdoenzymes of the dimethyl sulfoxide reductase (DMSOR) family catalyze a number of

77 Enzymes belonging to the bacterial dimethyl sulfoxide reductase (DMSOR) family contain a metal-bis-p

78 of bis-molybdopterin enzymes of the dimethyl sulfoxide reductase (DMSOR) family.

79 ed with those of previously studied dimethyl sulfoxide reductase (DMSOr) models.

80 tic intermediate in the reaction of dimethyl sulfoxide reductase (DMSOR) with (CH(3))(3)NO has been p

81 Dimethyl sulfoxide reductase (DMSOR), trimethylamine-N-oxide redu

82 cofactor in Rhodobacter sphaeroides dimethyl sulfoxide reductase (DMSOR).

83 plastidial thiol peroxidases and methionine sulfoxide reductases employing a single cysteine residue

84 Methionine sulfoxide reductase enzymes MsrA and MsrB have complemen

85 droplets in a manner reversed by methionine sulfoxide reductase enzymes.

86 f recombinant Rhodobacter sphaeroides biotin sulfoxide reductase expressed in Escherichia coli.

87 gnificant homology to the peptide methionine sulfoxide reductase family of enzymes, specifically MsrA

88 s protein is the only member of the dimethyl sulfoxide reductase family of molybdopterin enzymes that

89 ydrogenase is a novel member of the dimethyl sulfoxide reductase family of molybdopterin-containing e

90 olybdenum containing enzymes of the dimethyl sulfoxide reductase family.

91 tudies of the molybdenum-containing dimethyl sulfoxide reductase from Rhodobacter sphaeroides have yi

92 Here, a methionine sulfoxide reductase gene (AdMsrB1) was identified by tra

93 eversion of knockout mutations in the biotin sulfoxide reductase gene, bisC, has 64% base sequence id

94 cter sphaeroides f. sp. denitrificans biotin sulfoxide reductase has been heterologously expressed in

95 sely related MGD-containing enzyme, dimethyl sulfoxide reductase, has indicated a number of conserved

96 principle, fluorogenic probes for methionine sulfoxide reductases have been developed.

97 are fused to form a bifunctional methionine sulfoxide reductase (i.e., MsrBA) enzyme.

98 and oxidized apoA-I treated with methionine sulfoxide reductase implicate oxidation of specific tyro

99 expression of Rhodobacter sphaeroides biotin sulfoxide reductase in Escherichia coli were modified, r

100 haracteristic supports a role for methionine sulfoxide reductase in redox signaling.

101 repair of oxidized calmodulin by methionine sulfoxide reductase induces comparable changes in alpha-

102 However, the identity of all methionine sulfoxide reductases involved, their cellular locations

103 the active site cysteine of mouse methionine sulfoxide reductase is 7.2 even in the absence of substr

104 methionine residues performed by methionine sulfoxide reductase is important for the gastric pathoge

105 Biotin sulfoxide reductase is not reduced by biotin or the nonp

106 The results indicate that biotin sulfoxide reductase is thermodynamically tuned to cataly

107 Deletion or mutation in conserved methionine sulfoxide reductases leads to aging and several human ne

108 cepted, primarily from studies on methionine sulfoxide reductase (Msr) A, that the biological reducin

109 The methionine sulfoxide reductase (MSR) enzyme converts MetSO back to

110 Methionine sulfoxide reductase (MSR) enzyme converts MetSO back to

111 ioxidant enzymes, among which are methionine sulfoxide reductase (Msr) enzymes, which are critical fo

112 The role of methionine sulfoxide reductase (Msr), a methionine repair enzyme, i

113 phaS are excellent substrates for methionine sulfoxide reductase (Msr), thereby providing an efficien

114 de can be repaired back to Met by methionine sulfoxide reductase (Msr).

115 the reducing requirement for the methionine sulfoxide reductases (Msr), we have shown that thioredox

116 e sulfoxide (MetO) is mediated by methionine sulfoxide reductases (Msr).

117 nal changes through the action of methionine sulfoxide reductases (Msr).

118 Here we used yeast methionine sulfoxide reductases MsrA and MsrB to address this hypot

119 pair oxidized residues, including methionine sulfoxide reductases MsrA and MsrB, which reduce methion

120 RecA activity were suppressed by methionine sulfoxide reductases MsrA and MsrB.

121 ulting methionine sulfoxides by methionine-S-sulfoxide reductase (MsrA) and methionine-R-sulfoxide re

122 reduced back to methionines by methionine-S-sulfoxide reductase (MsrA) and methionine-R-sulfoxide re

123 in proteins can be repaired by methionine-S-sulfoxide reductase (MsrA) and methionine-R-sulfoxide re

124 Peptide methionine sulfoxide reductase (MsrA) repairs oxidative damage to m

125 Peptide methionine sulfoxide reductase (MsrA) reverses oxidative damage to

126 have investigated the ability of methionine sulfoxide reductase (MsrA) to maintain optimal calmoduli

127 A gene homologous to methionine sulfoxide reductase (msrA) was identified as the predict

128 The yeast peptide-methionine sulfoxide reductase (MsrA) was overexpressed in a Saccha

129 We report that peptide methionine sulfoxide reductase (MsrA), a repair enzyme, contributes

130 carboxyl terminus of the peptide-methionine sulfoxide reductase (MsrA), a repair enzyme, from Helico

131 nrelated protein known as peptide methionine sulfoxide reductase (MsrA), an antioxidant repair enzyme

132 in cytochrome c peroxidase (ccp), methionine sulfoxide reductase (msrA), or the metal-binding protein

133 lpha/beta-type SASP with peptidyl methionine sulfoxide reductase (MsrA), which can reduce methionine

134 med this compound by import and methionine-S-sulfoxide reductase (MsrA)-dependent reduction, but meth

135 that of only one protein, peptide methionine sulfoxide reductase (MsrA).

136 readily repaired by the action of methionine sulfoxide reductase (MsrA).

137 Peptide methionine sulfoxide reductase (MsrA; EC ) catalyzes the reduction

138 Peptide methionine sulfoxide reductase (MsrA; EC ) reverses the inactivatio

139 Peptide methionine sulfoxide reductase (MsrA; EC 1.8.4.6) is a ubiquitous p

140 Peptide methionine sulfoxide reductases (MsrA) from many different organism

141 S) elements, one of which was a methionine-R-sulfoxide reductase (MsrB) homolog from Metridium senile

142 -sulfoxide reductase (MsrA) and methionine-R-sulfoxide reductase (MsrB).

143 -sulfoxide reductase (MsrA) and methionine-R-sulfoxide reductase (MsrB).

144 -sulfoxide reductase (MsrA) and methionine-R-sulfoxide reductase (MsrB).

145 oreover, we show that periplasmic methionine sulfoxide reductase (MsrP) is part of the Cpx regulon.

146 periplasmic molybdenum-dependent methionine sulfoxide reductase (MsrP).

147 Methionine sulfoxide reductases (MSRs) are key enzymes in the cellu

148 Methionine sulfoxide reductases (Msrs) are oxidoreductases that cat

149 reversible through the action of methionine sulfoxide reductases (MSRs), which play key roles in lif

150 thionine residues is catalyzed by methionine sulfoxide reductases (Msrs).

151 ized, and subsequently reduced by methionine sulfoxide reductases (Msrs).

152 zed by a family of enzymes called methionine sulfoxide reductases (MSRs).

153 d is regulated by the cytoplasmic methionine sulfoxide reductase Mxr1 (MsrA) and a previously unident

154 a model, we show that of the two methionine sulfoxide reductases (MXR1, MXR2), deletion of mitochond

155 In contrast, CshA- and methionine sulfoxide reductase-negative (MsrA-) strains neither adh

156 he ycbX- and yiiM-dependent pathways, biotin sulfoxide reductase plays also a role in the detoxificat

157 The enzyme peptide Met sulfoxide reductase (PMSR) catalyzes the reduction of Me

158 Peptide methionine sulfoxide reductase (PMSR) is a ubiquitous enzyme that r

159 ants and a mutant lacking peptide methionine sulfoxide reductase (pmsr2-1) showed increased protein o

160 1 cells expressing a yeast free methionine-R-sulfoxide reductase proliferated in the presence of eith

161 The highly conserved methionine sulfoxide reductases protect proteins from oxidative dam

162 y evolved Sec-containing forms of methionine sulfoxide reductases reflect catalytic advantages provid

163 icroM for reduced methyl viologen and biotin sulfoxide reductase, respectively.

164 Reversing oxidation with methionine sulfoxide reductase restored HDL's ability to activate L

165 g the structures for R. sphaeroides dimethyl sulfoxide reductase, Rhodobacter capsulatus dimethyl sul

166 e intracellular and extracellular methionine sulfoxide reductases (SpMsrAB1 and SpMsrAB2, respectivel

167 MsrPQ is a newly identified methionine sulfoxide reductase system found in bacteria, which appe

168 n-Benson-Bassham, dinitrogenase and dimethyl sulfoxide reductase systems, were probed in strains grow

169 MtsZ is a molybdenum-containing methionine sulfoxide reductase that supports virulence in the human

170 (2-Ad = 2-adamantyl, DMSOR = dimethyl sulfoxide reductase, TMAOR = trimethylamine N-oxide redu

171 UGA) of Mycoplasma pneumoniae and methionine sulfoxide reductase (two UGAs) of Mycoplasma genitalium.

172 eins involving the enzyme peptide methionine sulfoxide reductase type A (MSRA) is postulated to serve

173 man spectra previously reported for dimethyl sulfoxide reductase, vibrational modes associated with a

174 Biotin sulfoxide reductase was also capable of reducing nicotin

175 (MsrA)-dependent reduction, but methionine-R-sulfoxide reductases were not involved in this process,

176 Methionine sulfoxide reductase, which reduces methionine sulfoxide

177 Most cells contain methionine sulfoxide reductases, which catalyze a thioredoxin-depen

178 Reduction back to methionine by methionine sulfoxide reductases would allow the antioxidant system