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2 Mutator (Mu) transposon lines identified the supernumerary aleurone layers 1-1 (sal1-1) mutant line c
5 of some or all of these Hox genes results in supernumerary and/or ectopic PGCs, either individually o
6 tholog in Caenorhabditis elegans, results in supernumerary apoptotic corpses, whereas its overexpress
8 al nervous systems, including the removal of supernumerary axonal inputs from neuromuscular junctions
9 Knockdown of Hap1 promotes specification of supernumerary axons in primary hippocampal neurons and p
12 esult from reciprocal interchanges between a supernumerary B chromosome and an arm of an essential A
21 excess Buc disrupts polarity and results in supernumerary Balbiani bodies in a 3'UTR-dependent manne
22 the developing avian neural tube resulted in supernumerary blood vessel ingression points and disrupt
23 non-heparin-binding VEGF121 did not produce supernumerary blood vessel ingression points, although t
27 cumferential vessels in 20 (48.8%), terminal supernumerary branching in 17 (41.5%), regional capillar
29 ve phenotype and promoted the development of supernumerary carpels under water-stress conditions.
30 tion, the double-deficient embryos developed supernumerary cartilage elements in the zeugopod, reveal
31 lineage; loss of bazooka function results in supernumerary cell divisions and apoptotic cell death.
32 ift of the fate of progenitors away from the supernumerary cell type, while eliminating cells using l
33 ptosis, which remodels tissue by eliminating supernumerary cells, also contributes forces to a tissue
34 biquitination and promotes the generation of supernumerary centriolar foci, whereas ablation of USP33
35 t occur only once per cell cycle; otherwise, supernumerary centrioles can induce aneuploidy and tumor
38 y long centrioles but also produced atypical supernumerary centrioles that grew from these long centr
39 y cells from Cep290-deficient mice exhibited supernumerary centrioles, decreased replication fork vel
40 ocious degradation of cyclin B by the APC/C, supernumerary centrioles, lagging chromosomes, and aneup
44 ntriole, a molecular mechanism that controls supernumerary centrioles/centrosomes and the maintenance
46 demonstrate that although most cells reduce supernumerary centrosomes after tetraploidization, a sma
47 Elevated Plk4 in mouse fibroblasts produced supernumerary centrosomes and enhanced the expected mito
48 xed tissue sections revealed the presence of supernumerary centrosomes and lagging chromosomes among
50 trically dividing neuroblasts, which display supernumerary centrosomes and spindle abnormalities duri
51 d to the appearance of tetraploid cells with supernumerary centrosomes and, ultimately, to cell death
55 lts indicate that oligoclonal aneuploidy and supernumerary centrosomes are early hallmarks of Bax-ind
56 We conclude that, independent of p53 status, supernumerary centrosomes are not sufficient to drive tu
58 of aneuploid cancer cells, we tested whether supernumerary centrosomes are sufficient to drive tumor
60 at disruption of interphase cell behavior by supernumerary centrosomes contributes to pathology indep
63 echanistically, tumor endothelial cells with supernumerary centrosomes had less centrosome-localized
64 n of this synchrony causes defects including supernumerary centrosomes in cancer and perturbed ciliar
65 r mitosis where a131's ability to de-cluster supernumerary centrosomes in cancer cells eliminates Ras
67 ice, Bax expression increased aneuploidy and supernumerary centrosomes in p53-/- mice but not in p53+
70 cal and ultrastructural examination of these supernumerary centrosomes revealed that inactivation of
72 wn that griseofulvin forces tumor cells with supernumerary centrosomes to undergo multipolar mitoses
73 Furthermore, the ability of HBV to induce supernumerary centrosomes was dependent on the presence
77 ent of aneuploidy followed the prevalence of supernumerary centrosomes within distinct cell populatio
79 many solid tumors have been found to contain supernumerary centrosomes, a condition known as centroso
80 riggered dysplastic mitoses, accumulation of supernumerary centrosomes, abnormalities of the mitotic
81 SV40 ST expression and show that ST induces supernumerary centrosomes, an activity we also demonstra
82 bnormal mitotic spindle structure, including supernumerary centrosomes, and changes in POC1A were acc
83 multiple defects in mitosis and cytokinesis, supernumerary centrosomes, and compromised cell-cycle ch
85 cells have centrosome aberrations, including supernumerary centrosomes, and this correlates with aneu
86 e of proliferation, to suppress formation of supernumerary centrosomes, and to maintain genomic integ
88 rference produced multinucleated cells, with supernumerary centrosomes, multipolar spindles and laggi
98 ple CFs; an activity-dependent regression of supernumerary CFs ultimately yields a single innervation
99 n cells with cytoskeletal protein mutations, supernumerary ChR1 patches remained adjacent to acetylat
101 [PSI (+)]-containing strains could lead to a supernumerary chromosome due to the presence of the ade1
103 eved by fertilization with sperm bearing the supernumerary chromosome paternal sex ratio (PSR), which
105 significance of the EBR1 family expansion on supernumerary chromosomes and whether EBR1 paralogues ar
106 that pathogenic forms of this fungus harbour supernumerary chromosomes with a wide variety of genes,
107 rate a remarkable excess of centrioles, with supernumerary cilia but deficient Hedgehog signaling.
109 maging to observe competitive elimination of supernumerary climbing fibers (CFs) in the cerebellum of
114 LP1 mutations, including point mutations and supernumerary copy variants, lead to severe and fatal di
116 in vitro in explant assays appears to induce supernumerary cusp formation in wild-type tooth germs.
117 there is a high degree of similarity in the supernumerary cusp patterns of mice lacking Sostdc1 or S
118 he location, number, incidence, and shape of supernumerary cusps in molars at embryonic day 15.5.
119 ia eutropha and Hydrogenovibrio marinus, two supernumerary Cys residues coordinate the proximal [FeS]
120 nitor cells, and when overexpressed leads to supernumerary DA neurons in the forebrain of zebrafish.
121 ve robust digits, but a very small, possibly supernumerary digit preserved on the manus suggests the
123 se Posterior Limb Bud-4 cell line can induce supernumerary digits, including digits with posterior ph
126 onic/early larval pigment pattern forms, but supernumerary early larval melanophores persist in ectop
127 ator of melanophore development, resulted in supernumerary ectopic iridophores while loss of foxd3, a
131 mpanying loss of individual fitness) by this supernumerary fertilization product was dependent upon c
133 r cells prior to fusion, causes formation of supernumerary fibers, suggesting that cells in the myobl
134 that these cells are responsible for seeding supernumerary fibers, when DVM FCs are eliminated prior
137 ence and floral meristems, the production of supernumerary flowers and floral organs, and a delay in
139 yonic fibroblasts, the tumor cells contained supernumerary functional centrosomes with intact centrio
140 n(S270A), which facilitates the formation of supernumerary GABAergic synapses in vitro, favors dendri
141 emagglutinin (HA) inserted as an additional, supernumerary gene between the HPIV3 P and M genes.
143 erted individually or in homologous pairs as supernumerary genes in the promoter proximal position of
144 creased expression of one or more of the 231 supernumerary genes on the extra copy of chromosome 21.
146 mesial lesion who sporadically experiences a supernumerary 'ghost' left arm that occupies the previou
147 d the formation of small, heterogeneous, and supernumerary glomeruli that failed to undergo neural pr
149 n of Corti is severely disrupted, exhibiting supernumerary hair cells at the apex, showing mirror-ima
150 nalling [mindbomb mutant or Su(H) morphant], supernumerary hair cells develop and otolith precursor p
152 lacking the Notch ligand JAG2 differentiate supernumerary hair cells in the cochlea, consistent with
154 ological defects of the organ of Corti, with supernumerary hair cells, as also reported for Hes5 null
158 ce displayed variable hypodontia, occasional supernumerary incisors and molars, as well as crown and
162 n caused all cells of the placode to form as supernumerary IPC NBs, indicating that the placode is in
163 uplications, interstitial triplications, and supernumerary isodicentric marker chromosomes, as well a
164 opic ureteric buds that will ultimately form supernumerary kidneys, a phenotype indistinguishable to
165 , an intracellular Ret inhibitor, results in supernumerary kidneys, megaureters, and hydronephrosis i
166 of smaller caliber) and that the presence of supernumerary large caliber Mauthner axons can profoundl
168 ive MMP3 in mouse mammary epithelia triggers supernumerary lateral branching and, eventually, tumors.
171 ry and sufficient to induce the formation of supernumerary limbs from blastemal tissue in axolotl sal
173 oss of Fgf20 delays formation of Eda-induced supernumerary mammary buds and normalizes the embryonic
175 , X and Y between spermatozoa with the small supernumerary marker chromosome (sSMC; sSMC(+)) and sper
176 associated with a distinct phenotype, and a supernumerary marker chromosome, +der(8)(8p23.1pter), wh
182 A-insensitive mutant led to the formation of supernumerary megaspore mother cells, suggesting that TE
183 positive (microtubule-associated protein 1B) supernumerary microtubule loops is elevated in dfmr1 nul
187 Dll dsRNA-injected larvae underwent numerous supernumerary molts, which could be terminated with inje
188 f fish or fly Nkx6 is sufficient to generate supernumerary motoneurons in both zebrafish and flies.
189 For this reason we examined the timing of supernumerary nerve terminal elimination at synapses in
190 erved a dramatic delay in the elimination of supernumerary nerve terminals from synapses in the levat
191 extensive neuronal sprouting, including many supernumerary neurites and terminal branches as well as,
192 ing Arm activity in immature INPs suppresses supernumerary neuroblast formation in brat mutant brains
193 ecification of INP identity and enhances the supernumerary neuroblast mutant phenotype in brat mutant
194 n mitotic neuroblasts and suppression of the supernumerary neuroblast phenotype induced by increased
196 with ectopic basal aPKC is the appearance of supernumerary neuroblasts in twins mutant brains or twin
197 ducing Arm activity also strongly suppresses supernumerary neuroblasts induced by overexpression of k
199 ensive hyperplasia of hematopoietic tissues, supernumerary neuronal cells, and head involution failur
201 These results may reflect the presence of supernumerary neurons beneath the cortical plate that co
212 to various developmental defects, including supernumerary or missing teeth, enamel and dentin hypopl
215 ncomplete resident hemocyte pattern, whereas supernumerary peripheral neurons induced by ectopic expr
216 ly, overactivation of these molecules causes supernumerary PGCs, their premature transit through the
217 regeneration, including the development of a supernumerary pharynx (the feeding organ of the animal)
220 misexpression of Wnt8 causes development of supernumerary placodes/vesicles, but this reflects poste
222 igurations, whereby the final coalescence of supernumerary poles into a bipolar array is inhibited.
225 pocampal), an enlarged posterior commissure, supernumerary pontine cholinergic and noradrenergic cell
226 ng with an enlarged posterior commissure and supernumerary pontine cholinergic and noradrenergic neur
227 n a wild-type limb bud causes formation of a supernumerary posterior digit (postaxial polydactyly), a
229 e duplications most often take the form of a supernumerary pseudodicentric derivative chromosome 15 [
230 cant target of DNA methylation that silences supernumerary rDNA units and regulates nucleolar activit
231 No evidence of transdifferentiation of these supernumerary SCs into HCs was observed in the p130(-/-)
232 dp null mutant flies show a specific defect (supernumerary scutellar bristles) known to be caused by
233 h cul-1 and lin-23 mutants the phenotypes of supernumerary seam cell divisions, defective alae format
235 t of nested inversions and at least one long supernumerary segment at the end of the chromosome.
236 advance cancer measurably, whereas a single supernumerary segment encompassing all four genes succes
239 increased floral organ merosity, especially supernumerary sepals, at incomplete penetrance in the fi
240 s unmasked multiple abnormalities, including supernumerary spermathecae, degenerative ovaries, and se
241 anscription factor results in development of supernumerary sporangia attached to a single seta, sugge
246 o the structural and functional roles of the supernumerary subunits and reveal new information on the
247 cantly extend knowledge of how the mammalian supernumerary subunits are arranged around the core enzy
248 al stalk and that the N termini of the other supernumerary subunits are on the same side of the membr
249 d core subunits and 31 mitochondria-specific supernumerary subunits are resolved within the L-shaped
250 is high, we found notable differences in the supernumerary subunits Cox26 and Cox13; the latter exhib
251 mbrane domains of the b-subunit to which the supernumerary subunits e, f, and g and the membrane doma
252 talytic and peripheral stalk domains and the supernumerary subunits e, f, and g, but lacking membrane
254 ture provides insights into the roles of the supernumerary subunits in regulation, assembly and homeo
257 UFB11 encodes one of 30 poorly characterized supernumerary subunits of NADH:ubiquinone oxidoreductase
258 he membrane domain, subunit a and associated supernumerary subunits, kept in contact with the rotor t
259 d modelled all 45 subunits, including the 31 supernumerary subunits, to provide the entire structure
268 criptive, gene tree-based variants featuring supernumerary symbionts: prokaryotic partners distinct f
273 factor odd-skipped related-2 (Osr2) develop supernumerary teeth lingual to their molars because of e
276 ooth abnormalities, including hypodontia and supernumerary teeth, aberrant crown and root morphologie
277 ar teeth with extra cusps, and in some cases supernumerary teeth, the opposite of the mutant phenotyp
282 h development but was sufficient to suppress supernumerary tooth formation in the Osr2(-/-) mutant mi
283 n embryonic mouse oral epithelium results in supernumerary tooth formation, but the underlying mechan
286 exhibited formation and subsequent arrest of supernumerary tooth germs that correlated with downregul
287 Moreover, in contrast to complete lack of supernumerary tooth initiation in Msx1(-/-)Osr2(-/-) mic
288 rs and 60 transmembrane helices, identify 18 supernumerary transmembrane helices, and assign and mode
291 and multicystic kidneys that were caused by supernumerary ureteric buds that fail to separate from t
292 in axon guidance and cell migration, develop supernumerary ureteric buds that remain inappropriately
294 1, there are fewer secondary motoneurons and supernumerary ventral interneurons, suggesting Nkx6.1 pr
296 eres 2-7, which results in the production of supernumerary viscerosensory and somatosensory neurons o
298 own to have mild effects because most of the supernumerary X genes are inactivated and not affected b
299 Allometric analysis of SCA reveals that supernumerary X- and Y-chromosomes both cause disproport
300 tion; hypoplastic jaws crowded with multiple supernumerary, yet unerupted, teeth; and cerebellar inte