ライフサイエンスコーパス: supportive

1 ng in the clinic, and care remains primarily supportive.

2 n also initiate or exacerbate CKD, is merely supportive.

3 chondrial optic neuropathy in the US is only supportive.

4 all other clinical interventions are largely supportive.

5 Therapy still remains mainly supportive.

6 In a prespecified supportive analysis involving the same population, the s

7 ted that participants found the intervention supportive and a motivation for action.

8 Therapy is mainly supportive and depends on the cause(s) of damage.

9 Current treatment approaches are supportive and include transfusions, splenectomy, and ch

10 on target toxicities." Management is largely supportive and may include discontinuation of the specif

11 l health, management of established cases is supportive and remains challenging.

12 Contemporary management of MODS is entirely supportive, and no specific therapeutics have been shown

13 These four methods are mutually supportive, and pinpoint the locations of the spin label

14 re that future AADR meetings are respectful, supportive, and safe environments for all.

15 Treatment strategies for TBI are supportive, and the pathophysiology is not fully underst

16 ping arises from interdependent and mutually supportive astrocytic-neuronal signaling.

17 enhanced by regular professional contact and supportive behavioral change programs.

18 unication strategies to foster inclusive and supportive behaviors consistent with interprofessional c

19 a potential role for topical AhR agonists in supportive cancer care.

20 a functional impairment in MSC hematopoietic supportive capacity in vitro and in cotransplantation mo

21 Hematopoietic supportive capacity of MSCs was evaluated by transwell m

22 mmunosuppressive combination and controls on supportive care (11% versus 4%, respectively; P=0.30).

23 g nonsurgical therapy (10.6 months) and best supportive care (3.7 months, P < 0.001).

24 eroid monotherapy and three (6%) patients on supportive care (odds ratio, 5.31; 95% confidence interv

25 zed in an acutely infected patient receiving supportive care alone to elucidate virus-host interactio

26 studies are needed to compare selinexor with supportive care alone, and to identify patient subgroups

27 he benefits of corticosteroid treatment over supportive care alone, mostly involving optimized renin-

28 rent therapeutic standards, which consist of supportive care and antibiotics.

29 ing patients who may benefit from aggressive supportive care and early intervention.

30 $177,496 for cabozantinib and $4630 for best supportive care and incremental cost-effectiveness ratio

31 s for the latter are becoming available, but supportive care and nonspecific support for hemostasis w

32 mmends that the current standard of care for supportive care and pain management-analgesia, adjunct t

33 systemic anticancer therapy, and referral to supportive care and pain management-be applied.

34 ed over the past two decades owing to better supportive care and recent introduction of novel targete

35 ity related to either AKI or CRS, apart from supportive care and volume status management.

36 tion, all the patients received high-quality supportive care as background therapy, including the ant

37 th AML but is largely attributed to enhanced supportive care as opposed to the development of better

38 ices for the delivery of oral anticancer and supportive care drugs was performed to April 2019 using

39 with information and the need for additional supportive care for allergies.

40 sus diagnostic guidelines are now available, supportive care has improved, there is greater understan

41 Dramatic improvements in treatment and supportive care have resulted in a growing adult survivo

42 Adverse events were manageable with supportive care implementation.

43 Multinational Association of Supportive Care in Cancer/International Society of Oral

44 ive mindsets have the potential to transform supportive care in oncology.

45 erapies have emerged as important aspects of supportive care in patients with MM.

46 $56,621 for cabozantinib and $2064 for best supportive care in the German model resulting in increme

47 and effectiveness of cabozantinib with best supportive care in the second-line treatment of advanced

48 ter diagnosis, AYA patients may benefit from supportive care interventions administered during the se

49 and test population-specific palliative and supportive care interventions to ensure generalizability

50 esis, and very few studies of therapeutic or supportive care interventions.

51 Full supportive care is recommended for at least 72 hours fro

52 Intensifying supportive care may be appropriate for subgroups identif

53 ally ill hospitalized patients, and standard supportive care measures for those with sepsis-induced c

54 erate a consensus management strategy on the supportive care of patients with SCID.

55 n more challenging with therapeutic than for supportive care oncology biosimilars.

56 9/10 making a full or partial recovery with supportive care only; (ii) inflammatory CNS syndromes (n

57 ived chemotherapy only; and 5% received best supportive care or placebo.

58 Applied therapies were supportive care or systemic immunomodulating therapies,

59 e randomly allocated 145 patients to receive supportive care plus eltrombopag (n=98) or placebo (n=47

60 n-dependent beta-thalassemia to receive best supportive care plus luspatercept (at a dose of 1.00 to

61 disease, and alpha-fetoprotein level to best supportive care plus oral regorafenib 160 mg or placebo

62 , sustainable early diagnosis, treatment and supportive care programmes with the potential to achieve

63 Early monitoring and administration of supportive care reduce mortality and clinically usable b

64 ent and infections, days of hospitalization, supportive care requirements, and performance indices.

65 vidence-based guidelines for the delivery of supportive care to patients admitted to Ebola treatment

66 brain tumors, including systemic therapy and supportive care topics.

67 ast 18 years, admitted to the palliative and supportive care unit at the University of Texas MD Ander

68 pital stay of less than 48 hours for routine supportive care was provided for three patients.

69 ntervention, provided that all the necessary supportive care were initiated early and the disease was

70 service delivery and access to non-dialytic supportive care when needed; minimise the financial burd

71 lastic leukemia (ALL) by providing excellent supportive care while receiving intensive chemotherapy a

72 mucormycosis with aggressive antifungal and supportive care without surgical intervention, provided

73 ion, prophylaxis of allograft rejection, and supportive care would assist hematopoietic and lung tran

74 pies (systemic immunomodulating therapies or supportive care) for SJS/TEN were selected.

75 patients recovered with cessation of vaping, supportive care, and steroid therapy and remained sympto

76 er availability of reperfusion therapies and supportive care, but adherence to secondary prevention s

77 related to service allocation, clinical and supportive care, clinical trial participation, and ethic

78 on and treatment of tuberculosis and improve supportive care, in particular the correction of hypoxem

79 ld upon existing theories and evidence about supportive care, specifically in relation to the hospita

80 peutic agents, and the need for HIV-specific supportive care, such as infection prophylaxis.

81 Supportive care, the central pillar of oncology nursing,

82 te trends in improved survival due to better supportive care, up to 40% of patients will have refract

83 nia, and sepsis have yielded improvements in supportive care, which have translated into improved pat

84 s (10 mg per day) or placebo, both with best supportive care, with stratification by tumour origin, W

85 tment and improved diagnostic procedures and supportive care.

86 nib is not cost-effective compared with best supportive care.

87 lity-adjusted life years) compared with best supportive care.

88 ons for hospitalized patients are limited to supportive care.

89 risk of death who may benefit from enhanced supportive care.

90 All patients received best supportive care.

91 rt, both were reduced by early diagnosis and supportive care.

92 und debridement, antitoxin, antibiotics, and supportive care.

93 and respect, communication and autonomy, and supportive care.

94 ere anticipated and managed with appropriate supportive care.

95 upport, surfactant treatment and elements of supportive care.

96 than 70%, but decreased with improvements in supportive care.

97 med and underpinned by existing knowledge of supportive care.

98 ves analgesics, anti-inflammatory drugs, and supportive care.

99 h either immunosuppressive regimen than with supportive care.

100 atments on a background of multidisciplinary supportive care.

101 ients, guide treatment decisions, and target supportive care.

102 merging infections to be treated solely with supportive care.

103 plement one another to provide comprehensive supportive care.

104 pneumonia are limited and mainly consist of supportive care.

105 ether 2(nd)-line-chemotherapy (2LCTX) + best-supportive-care (BSC) benefits patients with advanced bi

106 created a largely unexplored gap in patient supportive-care approaches.

107 es, as well as with mammalian haematopoietic-supportive cells to further the understanding of the evo

108 have been traditionally described as passive supportive cells, studies during the last decade have sh

109 mic blasts but instead on a subpopulation of supportive cells.

110 This document intends to standardize supportive clinical care of patients with SCID from diag

111 currently recommended owing to a paucity of supportive clinical data.

112 ttendance at the CLTS meeting, the number of supportive community leaders, the expectation of partici

113 A new initiative aims to create a supportive community to foster communication between sci

114 om harsh deprived conditions in infancy into supportive conditions in childhood and adolescence.

115 itory verbal hallucinations, compared with a supportive counselling control condition.

116 al (PFS) assessed by the log-rank test and a supportive Cox proportional hazards model.

117 using male and female urogenital specimens; supportive data from archived specimens were also includ

118 Supportive data from other VZV, PRV, and HSV1 laboratori

119 ronary revascularization lags despite robust supportive data, partly because of the handling characte

120 pic for discussion, but one that often lacks supportive data.

121 Altogether, the supportive effects of PD-1:28 engineering on T-cell func

122 anism possibly underlying some of the immune-supportive effects of sleep.

123 sis in the per-protocol efficacy population, supportive efficacy was analysed in the modified intenti

124 powerfully promote establishment of a tumor-supportive environment by inducing a novel reprogramming

125 with system-level interventions to create a supportive environment for implementation.

126 uality and sustainable patient care within a supportive environment for patients, their families, and

127 As we continue to build such supportive environments, we can see that they will use e

128 tal admissions, and treatment with lack of a supportive evidence base.

129 Our results provides supportive evidence for a mediating effect of the immune

130 the conformational immunoassay, and provide supportive evidence for its application in the developme

131 gainst primary dentition malocclusion but no supportive evidence for mixed dentition and permanent de

132 We find supportive evidence for our predictions using a sample o

133 This population-based study demonstrates supportive evidence for positive association of tobacco

134 The clinical data provide supportive evidence for the occurrence of disease antici

135 In addition to providing further supportive evidence for the use of coronary CT angiograp

136 edictor for the development of GA, providing supportive evidence of the potential value of nGA as a s

137 In sum, we provide supportive evidence that moderate and high intensity exe

138 tivation studies in carrier females provided supportive evidence that the GPC4 variants caused the co

139 in obesity-induced hypertension in mice, and supportive evidence was obtained in humans.

140 Despite no supportive evidence, various dosing schedules are used c

141 controlling for prematurity and analgesics, supportive experiences (e.g., breastfeeding, skin-to-ski

142 HR toppers are characterized by their supportive feel and high breathability whereas LR topper

143 Management is largely supportive, focusing on maintaining oxygenation and hydr

144 nical interventions, ranging from minimal or supportive for about one-third of cases to increasingly

145 al correlations (LRTCs) in cortex, which are supportive for decision-making and working memory tasks.

146 structural protein NS1, has been shown to be supportive for IAV replication.

147 phenotype of adjacent teeth seems to be more supportive for root coverage.

148 our current understanding of this metabolic supportive function of oligodendrocytes and its potentia

149 ys an antiviral role, we demonstrate a virus-supportive function of RSK1, migrating to the nucleus to

150 Thus, to confirm this finding, supportive functional analyses were performed on Shroom3

151 t viability and produce a significantly more supportive growth environment for PCa cells when grown i

152 gnificant, but with a significantly improved supportive hazard ratio.

153 master transcription factors, effectors, and supportive housekeeping genes required for establishing

154 Supportive housing addresses a fundamental survival need

155 We tested the association between supportive housing and diabetes outcomes among homeless

156 These findings show that benefits of supportive housing may be extended to diabetes care and

157 ity and STIs highlight the importance of the supportive housing program for youths aging out of foste

158 adults who were eligible for New York City's supportive housing program in 2007-2012.

159 CL2 secretion promotes accumulation of tumor-supportive immune cells in the cancer microenvironment,

160 microenvironment, thereby revealing a tumor-supportive immune-modulatory role of the TRAIL/TRAIL-R s

161 Timely monitoring of AcCl reagent was supportive in both sequential and simultaneous deprotect

162 in metastasis, while the post-EMT cells were supportive in promoting tumor invasion and angiogenesis.

163 ical syndrome, but in some patients, further supportive information is obtained from cerebrospinal fl

164 tend-and-befriend is mainly shown towards a supportive ingroup, regulated by cortisol.

165 I was fortunate to practice science in very supportive institutions and with very collaborative coll

166 -based policy scenarios for incentivisation, supportive instruments proved polarising.

167 All patients were given appropriate supportive intensive care for what was initially suspect

168 owledge gaps and improves outcomes, create a supportive international network for knowledge transfer

169 potentially vulnerable patients and warrants supportive interventional strategies to facilitate their

170 interventions, physical activity, education, supportive interventions, and other behavioral intervent

171 I renal cell carcinoma (RCC), albeit without supportive level I evidence.

172 n (hsa)-miR-483-3p was higher in endothelial-supportive M2-type macrophages (M2MPhis) and in the aort

173 ls with COVID-19 includes best practices for supportive management of acute hypoxic respiratory failu

174 utritional interventions is routine in their supportive management.

175 packed cells and eliminate the influence of supportive materials, making them less cumbersome during

176 re or less aggressive therapy and additional supportive measures during and after treatment.

177 aggressive L-thyroxine replacement and other supportive measures in the inpatient setting.

178 In the case of anaphylaxis appropriate supportive measures including the use of oxygen and epin

179 eligibility, as well as adjusting or adding supportive measures to the treatment plan to maximize su

180 Although recovery with delivery or supportive measures was possible in most cases, 11 of 70

181 Management of I-R injury relies primarily on supportive measures, as specific treatment strategies ar

182 abling identification and targeting of tumor-supportive mechanisms for novel treatment modalities.

183 al care, and limitations in the provision of supportive medical care.

184 his development and advances in the field of supportive medicine have changed the standard of care, w

185 lude early exposure and access to resources, supportive mentoring networks and comprehensive training

186 Molecular diagnostics provided a supportive microbiological diagnosis for 21 patients and

187 mesenchymal stromal cells that constitute a supportive microenvironment for hematopoietic stem and p

188 c regeneration, which requires a healthy and supportive microenvironmental niche within the bone marr

189 There is still an urgent need for supportive minimally invasive and cost-effective biomark

190 phase 2 results of every 8 weeks dosing, and supportive modelling, underpin further evaluation of eve

191 preparedness, mutuality, and availability of supportive networks influence QoL of MCS patients and th

192 IL-1beta-expressing cancer cells served as a supportive niche also for coexisting IL-1beta-lacking ca

193 remodel their microenvironment to maintain a supportive niche.

194 ggest that when an AFE is suspected, initial supportive obstetric care is important, but having an ob

195 These results provide evidence supportive of a causal association between abdominal adi

196 Supportive of a causal relationship, genetically predict

197 end protection, suggesting that the data is supportive of a critical role for t-loops in protecting

198 (12) or C(6)D(12) gives a KIE = 2.5 +/- 0.1, supportive of a HAA formation pathway.

199 ere found on 1 haplotype in 6 families each, supportive of a single mutation event inherited from a c

200 ctional analysis of the role of Brachyury is supportive of a Wnt-Brachyury feedback loop during PAE i

201 of NifD and NifK in a defined stoichiometry supportive of activity.

202 elucidated but overall, our findings are not supportive of an autoimmune process as a cause of sDM in

203 he key intermediate in methane oxidation) is supportive of an open-core structure.

204 HF or death, with inflection points for risk supportive of ARIC-based limits.

205 ides specificity, toxicity and efficacy data supportive of clinical development of genome editing to

206 n clinical trials, with mechanisms of action supportive of evaluation for efficacy in osteoarthritis.

207 from other normal human cell types are fully supportive of FeLV replication, innate resistance of blo

208 complete HSC niches, which are functionally supportive of hematopoietic tissue.

209 stems are more robust, diverse, complex, and supportive of human life than any technology yet created

210 to create an intracellular milieu optimally supportive of its replication and spread.

211 previous reports that synergy dominates yet supportive of more recent studies that find more antagon

212 eleased by young bone marrow cells were more supportive of myotube differentiation in vitro.

213 cate that sequences inhibitory to as well as supportive of Nef activity reside in this region.

214 ud-to-ground flashes were negative polarity, supportive of net negative charge within the plume.

215 ly absorbed and exhibited a plasma half-life supportive of once-daily dosing.

216 lar chondrocytes maintained under conditions supportive of osteogenesis in vitro.

217 , combined with bioinformatics evidence, are supportive of phase separation as a general mechanism co

218 d ~30% decrease in litter size was observed, supportive of placental insufficiency.

219 Our data provides information supportive of polyvalent vaccination approaches capable

220 Findings supportive of positive associations were reported for di

221 s retained after conjugation to the polymer, supportive of retention of effective therapeutic ability

222 effectiveness of such an intervention is not supportive of targeting limited resources for such use.

223 These results are supportive of the concept that G-quadruplex small molecu

224 sing this concept has been conducted, though supportive of the findings from observational studies.

225 It is hoped that this contribution will be supportive of the future development of additional effic

226 ators of oxidative and mitochondrial stress, supportive of their NETotic tendencies.

227 alities, and partial clinical stabilization, supportive of treatment response.

228 ge untreated attitudes were already strongly supportive of women before training.

229 ill supportive of women-were relatively less supportive of women than other groups, our diversity tra

230 se average untreated attitudes-whereas still supportive of women-were relatively less supportive of w

231 Mechanistic studies of the underlying tumor supportive onco-metabolism reveal coordinated activities

232 iotemporal transitions in the AGM region and supportive OP9 cell line.

233 Second, we examine potential supportive or offsetting mechanisms that promote childre

234 h can be either inhibitory, highly reactive (supportive) or non-reactive (neutral).

235 estine) and nerves projecting to the GIT and supportive organs.

236 ings are consistent with a possible role for supportive parenting and suggest a strategy for narrowin

237 preventive intervention focused on enhancing supportive parenting could ameliorate the association be

238 t most patients are not regular compliers in supportive peri-implant maintenance programs, it is of i

239 hree predictors (smoking, absence of regular supportive peri-implant maintenance, and placement of >=

240 of treated periodontitis, absence of regular supportive peri-implant maintenance, and use of bone gra

241 e parameters was influenced by the number of supportive peri-implant therapy visits (P < 0.01).

242 8 and July 2002, with implants enrolled in a supportive periodontal and peri-implant treatment follow

243 Patients did not receive regular supportive periodontal therapy (SPT) from 2 to 5 years p

244 atients' smoking habits and participation in supportive periodontal therapy were investigated.

245 n (IL)-1 polymorphism and counting number of supportive periodontal treatment (SPT) visits.

246 ic platform provided explanted human lungs a supportive, physiologic milieu and systemic regulation t

247 red to the current career landscape, and (2) supportive policies and tools outlined in postdoc handbo

248 in cancer patients and associated with tumor-supportive properties, as opposed to the high-density ne

249 Before and after 8 weeks of MORE or a supportive psychotherapy control, veterans receiving LTO

250 is relationship may be mediated by a lack of supportive relationships in adulthood.

251 , knowledge and a positive attitude; and (e) Supportive relationships-families could modify barriers

252 To create a supportive research culture in laboratories, the trainin

253 niche predicts worse prognosis, suggesting a supportive role for the V-SVZ environment in tumor initi

254 glial-like TBCs have been thought to play a supportive role in the taste bud, but little research ha

255 reased by grape powder feeding, suggesting a supportive role in tumor cell survival.

256 lant cells would not be possible without the supportive role of mitochondria.

257 identity; control over uncertainty; and the supportive role of others.

258 n-making, and (6) willing to fulfill several supportive roles including patient advocate and the "hub

259 crotubule (MT) cytoskeleton serves as both a supportive scaffold for organelles and an arborized syst

260 rtunities to improve access to addiction and supportive services.

261 We suggest that DELC can serve as a useful supportive sign, not only for the presence of cognitive

262 life adversity may inhibit the formation of supportive social ties, and weak social support is itsel

263 was improved because of the recovery of the supportive stromal ME.

264 visits, reminders, audits and feedback, and supportive supervision) plus supplies for syphilis testi

265 ter crosswinds or headwinds, and depart with supportive tailwinds.

266 edly disrupts GSC maintenance, reduces tumor-supportive TAMs (M2), and potently inhibits GBM growth.

267 critical roles in maintaining GSCs and tumor-supportive TAMs in GBM, indicating that targeting Wnt/be

268 Melatonin might be regarded as an important supportive therapeutic agent to reduce the early degener

269 e robust evidence guiding the most effective supportive, therapeutic, and neurosurgical interventions

270 rrent treatments for COVID-19 are limited to supportive therapies and off-label use of FDA-approved d

271 er patients with SIRS respond differently to supportive therapies for shock.

272 standards of care consist of evidence-based supportive therapies.

273 l or group hypnotherapy or group educational supportive therapy (control group).

274 ronic diseases exercise could be utilized as supportive therapy for IBD patients.

275 nts together with patient stratification and supportive therapy has resulted in a moderate improvemen

276 Long-term survival with supportive therapy is poor.

277 ansplant candidates largely according to the supportive therapy prescribed by transplant centers.

278 lly associated with an E. coli infection and supportive therapy remains the mainstay of treatment.

279 Despite intravenous fluids and supportive therapy the patient's symptoms and condition

280 membrane oxygenation (ECMO) can be used as a supportive therapy to improve outcomes but evidence-base

281 All participants received supportive therapy with albumin.

282 apy would be more effective than educational supportive therapy, and that group hypnotherapy would be

283 2 weeks of either problem-solving therapy or supportive therapy.

284 are the risks of HSCT with those of lifelong supportive therapy.

285 to group hypnotherapy, and 54 to educational supportive therapy.

286 intensity, and was managed with conventional supportive therapy.

287 improve outcomes of children requiring this supportive therapy.

288 Disease affecting either of these supportive tissues can lead to irreversible blindness in

289 e in proportions and associated 95% CIs were supportive to the primary analysis.

290 d the degree to which the rearing family was supportive toward education.

291 Physicians might consider supportive treatment and watchful waiting in stable pati

292 ve extracorporeal CO2 removal is an accepted supportive treatment in chronic obstructive pulmonary di

293 The cornerstone of supportive treatment of this coagulopathy is management

294 engue is essential for providing appropriate supportive treatment to dengue patients with febrile ill

295 duals with the highest risk that may require supportive treatment.

296 nsivity, even years after they are placed in supportive, well-resourced families.

297 To test the hypotheses that birds select supportive winds and that selectivity is mediated by sea

298 gratory birds tend to associate with mild or supportive winds, whose speed and direction may change u

299 nt available, case management is essentially supportive with management of severe multiple organ fail

300 orally and spatially distinct haematopoietic-supportive zebrafish niches, as well as with mammalian h