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1 teinase K studies demonstrate that BbHtrA is surface exposed.
2 embrane, with its C-terminal variable region surface exposed.
3 ce; a few lipoproteins have been shown to be surface exposed.
4 ciated with spirochete outer membrane and is surface exposed.
5 parts of helices two and three are primarily surface-exposed.
6 in the absence of BamE, BamD indeed becomes surface-exposed.
7 self-assembling peptoid nanosheet containing surface-exposed Abeta42-recognizing loops is constructed
8 lysine residues of their collagen stalks and surface exposed acidic residues located in CR1 CCP24 and
10 ptors of H. pylori and show that HopQ is the surface-exposed adhesin that specifically binds human CE
12 ize various tissues requires the presence of surface-exposed adhesins that have been difficult to ide
15 itioned by the amino acid composition of two surface-exposed alpha-helices of the SSU: higher plant-l
16 bacterial two-hybrid analysis to identify a surface-exposed alpha-helix in the C-terminal mannosyltr
17 length distribution depend primarily on the surface-exposed amino acids in specific regions rather t
19 ng mismatches of HLA eplets-small patches of surface-exposed amino acids of the HLA molecule-instead
20 edimentation assays, we demonstrate that two surface-exposed amino acids, F80 and F130, are required
21 nontypeable Haemophilus influenzae (NTHi) is surface exposed and a leading vaccine candidate for prev
23 zinc finger and phosphorylation interface as surface exposed and available for subsequent reactions.
24 a dual orientation, existing infrequently as surface exposed and predominantly as internally oriented
25 ious studies have suggested that FTT0831c is surface exposed and required for virulence of Francisell
28 escence microscopy suggests that BoMan26B is surface-exposed and associated with the outer membrane,
29 ion involved complex interactions among both surface-exposed and buried capsid mutations that togethe
30 distribution revealed the importance of both surface-exposed and buried residues, with a few phenotyp
33 urface proteins, only SPy_2191 is conserved, surface-exposed and inhibits both GAS adhesion and invas
36 We show that BBA57, an outer membrane and surface-exposed antigen, is a major trigger of murine Ly
37 bacterial proteins, we thereby identified 72 surface exposed antigens and further prioritized candida
38 of Art v 1, in contrast to those expressing surface-exposed Art v 1, were hypoallergenic as they har
44 lipids (GSLs) are a family of highly diverse surface-exposed biomolecules that have been neglected as
45 tranasal application in mice, VNP expressing surface-exposed but not shielded allergen induced allerg
46 7 had sequence features of lipoproteins, was surface exposed by the criteria of in situ protease susc
47 istry of numerous probe molecules on various surfaces exposed by three very important metal oxides (Z
48 Rv0888 is an unusual membrane protein with a surface-exposed C-terminal sphingomyelinase domain and a
49 of Gram-positive bacteria contains abundant surface-exposed carbohydrate molecules that are highly c
54 to utilize a large family of highly related surface-exposed cell wall proteins, the lectin-like epit
55 ing a cleavable N-terminal signal peptide, a surface-exposed central passenger and an outer membrane
61 ssa) introduces carboxyl groups primarily in surface-exposed crystalline areas of the cellulosic subs
62 ation photochemically within beta2, a single surface-exposed cysteine of the beta2 subunit of Escheri
63 p53 in vitro via selective alkylation of two surface-exposed cysteines without compromising its DNA b
64 h 1 kD and 10 kD) were chemically coupled to surface exposed Cyt c lysine (Lys) residues using succin
65 e domain bound to a metal ion, we identify a surface-exposed di-histidine motif in MamO that contribu
68 The crystal structure of the C-terminal, surface-exposed domain of TraM was determined to 2.5 A r
69 mutations that alter the positively charged surface-exposed domain, we show that RcsF monitors later
70 initively; we argue that these molecules are surface-exposed (during apoptotic cell death), ubiquitou
72 Bacteroides ovatus encodes BoMan26B, a cell-surface-exposed endomannanase whose functional and struc
73 yeast Candida glabrata harbors more than 20 surface-exposed, epithelial adhesins (Epas) for host cel
74 onal manner by forming a spatially clustered surface-exposed epitope conferring optimal IgE-binding c
75 onservation among strains, and expression of surface-exposed epitopes suggest that NTHI1441 is a pote
79 bacteria use the toxic C-terminus of a large surface-exposed exoprotein to inhibit the growth of susc
80 argeting dopaminergic neurons, reaction with surface-exposed FLAG epitope-tagged D2R, and blocking of
83 otein-protein interface of intracellular and surface-exposed fusion complexes and investigated the ef
86 gosaccharides had affinity for the SusD-like surface-exposed glycan-binding protein, predicted to be
88 olyphleates (TPP) are high-molecular-weight, surface-exposed glycolipids present in a broad range of
90 hat the ligand binds with fast kinetics to a surface-exposed groove and that interactions at the iden
91 provide new insights into the repertoire of surface-exposed H. pylori proteins that may mediate bact
96 of FVII, the FVII GLA domain sits within the surface-exposed hexon trimer depression in a different o
97 ed for other AAVs but uniquely differ in the surface-exposed HI loop between betaH and betaI of the c
101 ents, and recent studies have shown that the surface-exposed HtaA protein binds both hemin and Hb and
102 es inside-out conformations where previously surface-exposed hydrophilic side chains get buried along
103 st that the amino acids making up the large, surface-exposed hydrophobic cap in the crystal structure
104 l side of this interface likewise involves a surface-exposed hydrophobic helix, namely, the D-helix o
106 the N-Cap amphipathic helix interacts with a surface-exposed hydrophobic patch on the core of the PAS
109 dy, we made site-directed mutagenesis on the surface-exposed hydrophobic residues of pvLAAD INS, and
110 ntially protein carbonylation, but increased surface-exposed hydrophobicity and decreased free thiols
111 eonine-rich region that provides an array of surface-exposed hydroxyl groups that bind to polyQ pepti
113 ch, we show here that the LTA polymer is not surface exposed in S. aureus, as it can only be detected
114 p123, a site buried in the Nef:SH3 dimer but surface exposed in the Nef:SH3-SH2 complex), showed a Hc
116 sine residues, which are buried in FVIII and surface-exposed in dissociated activated FVIII (dis-FVII
117 (C)-like domains of native TprC and TprI are surface-exposed in T. pallidum, whereas their MOSP(N)-li
122 aureus clone USA300 is a membrane-bound and surface-exposed lipoprotein that binds up to four Cu(+)
124 usly reported to form complexes with RcsF, a surface-exposed lipoprotein that triggers the Rcs stress
125 orferi outer membrane (OM) contains numerous surface-exposed lipoproteins but a relatively low densit
126 however, now suggest that the prevalence of surface-exposed lipoproteins has been underestimated.
127 There are few examples of Gram-negative, surface-exposed lipoproteins, and VolA is unique, as it
131 meric recombinant PorB loop mutants in which surface-exposed loop residues have been switched between
133 trypsin-like serine proteases have flexible surface-exposed loops and are known to adopt higher and
134 onses that are directed against six variable surface-exposed loops that differ in sequence depending
135 ory domains were inserted into nonconserved, surface-exposed loops that were tight and identified com
136 to sequences located in the putative Tp0126 surface-exposed loops, while phagocytosis assays showed
140 ons are largely mediated by three conserved, surface-exposed lysine residues (triK), which were previ
142 esis, which identifies two highly conserved, surface-exposed lysine residues in this region of the tr
143 iquibodies reliably transferred ubiquitin to surface exposed lysines on target proteins and even cata
146 on, bbk13, which encodes an immunogenic, non-surface-exposed membrane protein that is important for e
149 supplied for import and trafficking by cell-surface exposed metalloreductases, but specific cupric r
150 dies demonstrate that chemical alteration of surface-exposed moieties can confer gain-of-function glu
151 the canonical vancomycin binding site, these surface-exposed molecules confer increased vancomycin-re
152 eveals a high degree of allelic variation in surface-exposed molecules, including adhesins that promo
156 hat the myristoyl group lies in a relatively surface exposed "myristoyl nest." We propose that this s
158 t cell wall-anchored C terminus, whereas the surface-exposed N terminus is highly variable, a feature
159 ecombinant mutants of FI carrying additional surface-exposed N-glycosylation sites that were expected
161 molecular surface, with the vast majority of surface-exposed, nonconserved residues being clustered t
163 ite consists of a patch of residues that are surface-exposed on the face of the extracellular domain
164 jugates conjugated through either engineered surface-exposed or reduced interchain disulfide bond cys
167 Proteins that met multiple criteria for surface-exposed outer membrane localization included kno
168 mising means of vaccine development based on surface-exposed outer-membrane proteins and the design o
170 y imaging confirmed that antibodies targeted surface-exposed P6 of intact NTHi cells and not internal
171 sion and specifically illuminate the fate of surface-exposed parasite proteins during and immediately
172 ng signal peptide followed by an N-terminal, surface-exposed passenger domain and a C-terminal domain
173 of CagA sequences identified four conserved surface-exposed patches (CSP1-4), which represent putati
174 inates binding to the 70S ribosome via three surface-exposed patches of basic residues that we propos
178 of copper nitrite reductase by mutation of a surface-exposed phenylalanine residue (Phe306), located
179 between NrdH-redoxin and TrxR, where the two surface-exposed phenylalanines of TrxR perfectly fit int
180 is of apoptotic cells by bridging cells with surface exposed phosphatidylserine (PS) to macrophage re
182 haracterized with respect to the presence of surface-exposed pili, DNA uptake, and natural transforma
183 nds as an extended conformation in a narrow, surface-exposed pocket formed only in the DNA-bound stat
185 ucture-guided mutagenesis, we mutated all 38 surface-exposed polar residues of the rDer f 21 allergen
187 mpounds that target essential, nonredundant, surface-exposed processes in gram-negative bacteria.
188 ucture-based approach, we identified several surface-exposed proline residues in the nucleotide bindi
192 n of virulence by surfaces also requires the surface-exposed protein PilY1, which has a domain homolo
193 e concluded that S. suis BgaC is an atypical surface-exposed protein without the involvement of bacte
199 ence protein (Eap) and autolysin (Atl), both surface-exposed proteins containing repeating structures
200 a quantitative proteomic comparison of cell surface-exposed proteins in human cancer cells that were
202 ltiple mechanisms to alter the expression of surface-exposed proteins through the processes of phase
205 pe independent and mediated by the bacterial surface-exposed proteins, as pretreatment of pneumococci
206 n this study, the selective biotinylation of surface-exposed proteins, streptavidin affinity purifica
208 s spectrometry were used to characterize the surface-exposed proteome of M. avium subsp. hominissuis.
211 n as cell attachment factors by binding to a surface-exposed region in the protruding (P) domain of t
212 icted secondary structure of the C-terminal, surface-exposed region of OprF has high structural ident
213 of DBLbeta3_D4, these cluster to a defined, surface-exposed region on the convex surface of DBLbeta3
214 f transient interactions are correlated with surface exposed regions that exhibit a high propensity t
215 strain-specific sequence variability within surface-exposed regions (loops) putatively involved in T
216 structure-based mutagenesis scan identified surface-exposed regions and the interface between the su
217 sed to identify candidate ISDs residing near surface-exposed regions in Arabidopsis thaliana crucifer
218 odel-guided mutagenesis: three conserved and surface-exposed regions of modeled YscO were targeted fo
219 lutionary trace analysis to pinpoint several surface-exposed regions of potential functional importan
220 rential immune activation could be mapped to surface-exposed regions of the capsid, such as hypervari
221 ISDs are adjacent to or within hydrophilic, surface-exposed regions that serve to present them on th
222 re, we show that amino acid variation within surface-exposed regions within outer membrane P5 affecte
224 roteins were generated, each having a single surface-exposed residue mutated to alanine or a conserva
225 a conserved glycine at amino acid VP1-145, a surface-exposed residue that maps to the 5-fold vertex a
226 used by a Glu-26-Lys mutation that targets a surface-exposed residue unlikely to affect the intramole
228 ified tyrosine 280 in combination with other surface-exposed residues (the YNND epitope) as critical
231 Here, we report the results of probing 133 surface-exposed residues in RD3 by single substitutions
232 ed NMR spectral changes are observed for non-surface-exposed residues in the active site and on the d
235 h mild EI mutations were found to affect the surface-exposed residues of the K10 alpha helix coiled-c
237 D to 1.39 angstrom resolution and identified surface-exposed residues that, when substituted with ala
239 , we identified short-sequence homologies of surface-exposed residues within the human DSG1 ectodomai
240 Blo t 1, as well as of sequence identity of surface-exposed residues, suggests limited cross-reactiv
243 ve considerably increased in size, forming a surface-exposed ribosomal RNA (rRNA) shell of unknown fu
248 removal of all tail residues predicted to be surface-exposed significantly restores RNP bioactivity.
250 cts at the active site (Trp87) and a remote, surface-exposed site (Trp167), time-dependent Stokes shi
251 ved ECM is controlled by a novel, conserved, surface-exposed site on the thrombospondin L-type lectin
253 es or protein-protein/ligand interactions at surface-exposed sites of membrane protein complexes in w
254 is contacted by the core shell at 5 distinct surface-exposed sites, comprising VP1 residues 264 to 26
255 d sphingomyelinase successfully reduced cell surface-exposed sphingomyelin but did not significantly
261 nd Spy1728, were previously documented to be surface exposed, suggesting that our findings have trans
263 r dynamics, we recognize this weak spot as a surface exposed tetra-coordinated Al atom and further pr
264 d by excessive upward heat flux from the sea surface exposed to air in the region of sea ice loss.
265 As K stress increased, decreased mesophyll surface exposed to intercellular space and chloroplast d
267 rrent density radially inward on the silicon surface exposed to Triton((R)) X-100 containing HF based
268 ly due to the reduced hydrophobic pyrimidine surface exposed to water after anion aggregation, and th
269 oosmotic flow (EOF, i.e. the water flow over surfaces exposed to a weak direct current (DC) electric
271 , wind turbines, electrical lines, and other surfaces exposed to cold environments diminishes their s
272 cuticles and attracted water to hydrophobic surfaces exposed to high relative humidity due to its hy
273 the different plants and the normalizing the surfaces exposed to nanoparticles, the RHIZOtest demonst
274 formation of FH-sialic acid-C3b complexes on surfaces exposed to plasma is essential for preventing c
277 ems: across 31 trees in a Panama rainforest, surfaces exposed to sun were 8 degrees C warmer and vari
278 n was significantly greater on all patterned surfaces exposed to TGFbeta (P < 0.002), whereas cells g
279 xtent of heterogeneous nucleation at mineral surfaces exposed to the fluids in porous reservoirs.
280 m with pathologic bacteria can cover implant surfaces exposed to the oral cavity, for example, due to
283 sion to host epithelial cells is enhanced by surface-exposed translation elongation factor EF-Tu carr
285 model, electrostatic interactions as well as surface-exposed Tyr residues bind WaaG to the membrane.
286 ping experiments, a transient radical on the surface-exposed Tyr-337 was identified as the oxidation
288 of the viral capsid proteins where specific surface-exposed tyrosine (Y) and threonine (T) residues
289 Recent evidence suggests that the putative surface-exposed variable antigen TprK plays an important
293 support the idea that the lipase activity of surface-exposed VolA likely contributes to the success o
294 three key binding determinants located in a surface-exposed 'W56 loop' of PspF, which form a tightly
296 he proteins encoded by these two operons are surface exposed, which is consistent with the presence o
298 ence (PelB-MOSP), MOSP(C) is OM-embedded and surface-exposed, while MOSP(N) resides in the periplasm.
300 cted more weakly with zinc possessing a less surface-exposed zinc-binding site, and stayed monomeric.