ライフサイエンスコーパス: surveillance mechanism

1 targeted for destruction by a novel ribosome surveillance mechanism.

2 operates in vivo to augment the tumor immune surveillance mechanism.

3 ught to play a significant role in the tumor surveillance mechanism.

4 antibiotics, is controlled by a translation surveillance mechanism.

5 n [MSCI]) and is thought to act as a meiotic surveillance mechanism.

6 be part of a more general spindle checkpoint surveillance mechanism.

7 ranscript isoforms, including targets of RNA surveillance mechanisms.

8 gnant cells to resist apoptosis-based tumour-surveillance mechanisms.

9 increased tumorigenicity and can evade tumor surveillance mechanisms.

10 e destruction by macrophage-dependent immune surveillance mechanisms.

11 nts to agree to either long-term or lifelong surveillance mechanisms.

12 d by the meiotic cell cycle and monitored by surveillance mechanisms.

13 products that enable evasion of host immune surveillance mechanisms.

14 is and ability to escape p53-dependent tumor surveillance mechanisms.

15 n and differentiation, and diminishing tumor surveillance mechanisms.

16 ified of cases through various reporting and surveillance mechanisms.

17 toward reducing that burden without improved surveillance mechanisms.

18 ns involves both extracellular and cytosolic surveillance mechanisms.

19 This may represent one important surveillance mechanism against antinuclear autoimmunity

20 ally sensitize infected cells to this immune surveillance mechanism, an outcome that would have thera

21 ed from hospitalized cases, calls for robust surveillance mechanisms and infection prevention activit

22 el to investigate metastasis-specific immune surveillance mechanisms are also explored.

23 We suggest that these surveillance mechanisms arose when both S and M phases w

24 cing of endogenous coding genes by using RNA surveillance mechanisms as a safeguard to protect their

25 ells exhibited an apparently functional G2-M surveillance mechanism, as exemplified by a lack of both

26 r results provide evidence for a codon-based surveillance mechanism associated with the nucleus that

27 Our results suggest that a transcriptome surveillance mechanism based on random association of RN

28 eteriously activated as cellular defense and surveillance mechanisms break down with age.

29 tive complement pathway (ACP) functions as a surveillance mechanism by which microorganisms are opson

30 We also identified a mitochondrial surveillance mechanism by which mitochondrial dysfunctio

31 tivity before axon wrapping might serve as a surveillance mechanism by which OPCs determine the prese

32 Recently, we reported a novel ER surveillance mechanism by which proteins from the secret

33 During the meiotic cell cycle, a surveillance mechanism called the "pachytene checkpoint"

34 Defects in a cell cycle surveillance mechanism called the spindle checkpoint con

35 Surveillance mechanisms (checkpoints) exert quality cont

36 We conclude that mRNA decay and surveillance mechanisms collaborate in achieving fidelit

37 Surveillance mechanisms control accurate Csn subunit amo

38 We propose that an HDAC-dependent surveillance mechanism counteracts constitutive histone

39 In eukaryotic cells, surveillance mechanisms detect and respond to DNA damage

40 activating Ki-ras mutations may escape tumor surveillance mechanisms due to reduced responsiveness to

41 t NTA by the NatA complex acts as a cellular surveillance mechanism during stress and that imprinting

42 okeless tobacco use under global or national surveillance mechanisms (eg, Global Tobacco Surveillance

43 In mammals, surveillance mechanisms eliminate meiotic cells with def

44 In response to DNA damage, cell cycle surveillance mechanisms enable normal cells to arrest an

45 hese compartments, but it is unknown whether surveillance mechanisms exist to reinforce this function

46 data suggest that an alternative elongation surveillance mechanism exists in vivo to overcome arrest

47 of mitochondrial RNA is an intrinsic immune surveillance mechanism for cells to cope with mtDSBs, in

48 These findings suggest a novel surveillance mechanism for eliminating cells containing

49 The p53 pathway provides a surveillance mechanism for protein translation as well a

50 ein turnover by Hiw can function as a damage surveillance mechanism for responding to axonal injury.

51 Here we describe a genome surveillance mechanism for retrotransposons by transposa

52 We demonstrate a novel surveillance mechanism for the elimination of cells dama

53 These results suggest a conserved surveillance mechanism for translation termination.

54 early meiosis, suggesting sexually dimorphic surveillance mechanisms for telomere dysfunction during

55 poptosis induced by p53 are part of the host surveillance mechanisms for viral infection and tumor in

56 l defects associated with the failure of RNA surveillance mechanisms, further highlighting the import

57 lex processes of mRNA biogenesis, these mRNA surveillance mechanisms help to ensure the integrity of

58 n other systems, the RNA life cycle involves surveillance mechanisms, however, the details of RNA qua

59 ay constitute an innate immune translational surveillance mechanism important in host defense counter

60 ediated decay (NMD) is a posttranscriptional surveillance mechanism in eukaryotes that recognizes and

61 Here we show the existence of an innate host surveillance mechanism in macrophages that specifically

62 These findings uncover a surveillance mechanism in which tight control on the DLK

63 t distinct responses, providing insight into surveillance mechanisms in male meiosis.

64 d DNA damage response and escape from immune surveillance mechanisms in the pathogenesis of PTCL.

65 nce tumorigenesis, underscoring the powerful surveillance mechanisms in the skin.

66 thogen perturbations, plants mobilize backup surveillance mechanisms involving RKs and RLCKs to derep

67 One such surveillance mechanism is meiotic silencing, the inactiv

68 ne checkpoint gene, which suggests that this surveillance mechanism is widely conserved.

69 Cell cycle checkpoint, a major genomic surveillance mechanism, is an important step in maintain

70 During the translation surveillance mechanism known as ribosome-associated qual

71 kinetochore-microtubule attachments, a cell surveillance mechanism known as the spindle assembly che

72 Eukaryotic cells rely on a surveillance mechanism known as the spindle checkpoint t

73 In budding yeast, a surveillance mechanism known as the spindle position che

74 In budding yeast, a surveillance mechanism known as the spindle position che

75 Innate immune surveillance mechanisms lie at the heart of the antivira

76 germline apoptosis pathway, and that similar surveillance mechanisms may contribute to germline apopt

77 Existing surveillance mechanisms may underestimate the incidence

78 Therefore, a surveillance mechanism monitors spatial position in resp

79 accurate positioning of the spindle fails, a surveillance mechanism named the spindle position checkp

80 tella vectensis), suggesting that the genome surveillance mechanism of cGAS predates metazoan interfe

81 sults point towards the existence of a novel surveillance mechanism of microtubule integrity that may

82 inding protein is a novel nucleic-acid-based surveillance mechanism of RQC.

83 This review focuses on the surveillance mechanisms of the budding yeast S. cerevisi

84 monstrate that CD49a may contribute to local surveillance mechanisms of the T(RM) population.

85 Our results indicate that host surveillance mechanisms operate at multiple levels to re

86 BLM is likely to be part of a DNA surveillance mechanism operating during S phase.

87 of organisms have unveiled the existence of surveillance mechanisms or checkpoints that couple the f

88 cleaving embryos, DNA synthesis is short and surveillance mechanisms preserving genome integrity are

89 artly monitored by the spindle checkpoint, a surveillance mechanism preventing the cell from prematur

90 The surveillance mechanism responsible for the detection and

91 mination are key to the understanding of RNA surveillance mechanisms such as NMD and crucial for the

92 In turn, metazoans employ surveillance mechanisms such as the mitochondrial unfold

93 id genomic instability, cells have developed surveillance mechanisms such as the spindle assembly che

94 We propose that a HDAC6-dependent surveillance mechanism suppresses toxic tau accumulation

95 hus, Clec12a contributes to an innate-immune-surveillance mechanism that controls the expansion of po

96 We propose the existence of a surveillance mechanism that couples the balanced product

97 in budding yeast, which is part of a nuclear surveillance mechanism that degrades aberrant transcript

98 se-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that degrades mRNAs containing pr

99 ons in nonsense-mediated mRNA decay (NMD), a surveillance mechanism that degrades mRNAs with prematur

100 common with nonsense-mediated decay (NMD), a surveillance mechanism that degrades PTC-bearing mRNAs.

101 i by cGAS may act as a cell-intrinsic immune surveillance mechanism that detects a range of neoplasia

102 Nonsense-mediated mRNA decay (NMD) is a surveillance mechanism that detects and degrades transcr

103 iated mRNA decay (NMD) is the cell's natural surveillance mechanism that detects and destroys PTC-con

104 NMD is a surveillance mechanism that detects and eliminates aberr

105 SPOC is a surveillance mechanism that ensures alignment of the mit

106 er of the Unfolded Protein Response (UPR), a surveillance mechanism that ensures homeostasis of the e

107 The spindle checkpoint is a cell cycle surveillance mechanism that ensures the fidelity of chro

108 e for cell competition during adulthood as a surveillance mechanism that ensures tissue integrity dur

109 uivalent of mammalian centrosome) associated surveillance mechanism that halts mitotic exit upon spin

110 tivate the tumour suppressor p53 to elicit a surveillance mechanism that halts proliferation and prom

111 onsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that in mammals generally occurs

112 ive bacteria are specifically detected via a surveillance mechanism that involves activation of extra

113 spindle assembly checkpoint (SAC), a genome-surveillance mechanism that is important for cell surviv

114 NA decay (NMD) pathway is a highly conserved surveillance mechanism that is present in all eukaryotes

115 (p)ppGpp appear to be part of a surveillance mechanism that links nutrient availability

116 cellular response to DNA damage is a crucial surveillance mechanism that maintains genomic integrity

117 MAD1 and MAD2 act in a surveillance mechanism that mediates a metaphase delay i

118 se-mediated mRNA decay (NMD) is a eukaryotic surveillance mechanism that monitors cytoplasmic mRNA tr

119 Our results suggest a novel cell cycle surveillance mechanism that monitors nucleosome assembly

120 mRNA decay (NMD) pathway is an example of a surveillance mechanism that monitors premature translati

121 The spindle assembly checkpoint, a surveillance mechanism that operates in all cells to pre

122 s, an Aurora B gradient appears to mediate a surveillance mechanism that prevents chromosome deconden

123 checkpoint (SAC) has been viewed as the sole surveillance mechanism that prevents chromosome segregat

124 pindle assembly checkpoint (SAC), which is a surveillance mechanism that prevents premature chromosom

125 SAC is the critical surveillance mechanism that prevents premature chromosom

126 sw1 and the nuclear exosome ensures accurate surveillance mechanism that proofreads the efficiency of

127 In summary, we uncover a p53-dependent surveillance mechanism that protects against genome inst

128 les of Nup2 and NupA during mitosis and in a surveillance mechanism that regulates nucleokinesis when

129 interference is an evolutionarily conserved surveillance mechanism that responds to double-stranded

130 ets of nonsense-mediated mRNA decay (NMD), a surveillance mechanism that selectively degrades nonsens

131 protease subunit AFG3L2 is critical to this surveillance mechanism that we propose acts as a sensor

132 DNA damage activates TP53-regulated surveillance mechanisms that are crucial in suppressing

133 underscores the importance of defining tumor surveillance mechanisms that effectively target the dise

134 Large-scale, robust surveillance mechanisms that measure rather than estimat

135 Surveillance mechanisms that monitor protein synthesis c

136 SADD) theory postulates the presence of host surveillance mechanisms that monitor the integrity of co

137 Cell cycle checkpoints operate as DNA surveillance mechanisms that prevent the accumulation an

138 Cell cycle checkpoints are surveillance mechanisms that safeguard genome integrity.

139 However, surveillance mechanisms that specifically respond to sta

140 Cells rely on surveillance mechanisms that take care of the removal of

141 NGD) and non-stop decay (NSD) are eukaryotic surveillance mechanisms that target mRNAs on which elong

142 Thus, Crb may be part of a "surveillance mechanism" that is responsible for the cell

143 Mitotically dividing cells use a surveillance mechanism, the spindle assembly checkpoint,

144 inside the host by escaping the host immune surveillance mechanism through restricted protein expres

145 ecay (NMD) represents a highly conserved RNA surveillance mechanism through which mRNA transcripts be

146 dle assembly checkpoint (SAC) functions as a surveillance mechanism to detect chromosome misalignment

147 Cell competition has been proposed as a surveillance mechanism to ensure normal development and

148 g of how HIV subverts a normal immunological surveillance mechanism to establish primary infection.

149 of pre-malignant cells by healthy cells as a surveillance mechanism to prevent oncogenesis.

150 (ATR)-mediated S phase checkpoint acts as a surveillance mechanism to prevent rereplication.

151 ay (NMD) was originally conceived as an mRNA surveillance mechanism to prevent the production of pote

152 Thus, C. elegans has a surveillance mechanism to recognize ToxA through its eff

153 sis, however, thereby providing an efficient surveillance mechanism to sense the loss of Rb.

154 st and apoptosis as part of the overall host surveillance mechanism to ultimately block viral replica

155 egrating protein folding status with central surveillance mechanisms to balance proteome stability ac

156 mage-induced cell cycle checkpoints serve as surveillance mechanisms to maintain genomic stability, a

157 This suggests that mammalian hosts possess surveillance mechanisms to monitor pathogen-mediated alt

158 HIV-1 Nef protein suppresses multiple immune surveillance mechanisms to promote viral pathogenesis an

159 Therefore, cells have evolved surveillance mechanisms to restrict the mobility of thes

160 There are two major surveillance mechanisms to suppress ferroptosis: one med

161 DNA damage response is an important surveillance mechanism used to maintain the integrity of

162 host cell processes or cause damage, but the surveillance mechanisms used by animals to monitor these

163 s can exploit KZFPs to dampen TE-originating surveillance mechanisms, which likely facilitates clonal

164 nal transduction pathway as part of the host surveillance mechanisms, which ultimately induces the ir

165 ogenesis, and the ways they evade the immune surveillance mechanisms, will likely lead to the develop

166 ies have uncovered an RNA 5' capping quality surveillance mechanism, with DXO/Rai1 decapping enzymes

167 A reliable surveillance mechanism would either maintain our confide