ライフサイエンスコーパス: susceptibility gene

1 e report FAM222A as a putative brain atrophy susceptibility gene.

2 gene (FANCT) that also may be a rare cancer susceptibility gene.

3 on (TMLHE), recently identified as an autism susceptibility gene.

4 e TNFSF8 and not TNFSF15 as an important T1R susceptibility gene.

5 with its proposed role as a recessive cancer susceptibility gene.

6 , CHK2 is thought to be a multi-organ cancer susceptibility gene.

7 the SWEET sugar transporter and rice disease susceptibility gene.

8 ied recently as a novel Noonan syndrome (NS)-susceptibility gene.

9 ne-methyltransferase, is a key schizophrenia susceptibility gene.

10 sion, HOXB13 is not a material breast cancer susceptibility gene.

11 ona fide, definite evidence long-QT syndrome susceptibility gene.

12 since the identification of NOD2 as a major susceptibility gene.

13 s a novel pheochromocytoma and paraganglioma susceptibility gene.

14 GWA) mapping to identify potential candidate susceptibility genes.

15 hogenic mutations in highly penetrant cancer susceptibility genes.

16 y included SDHA, TMEM127, MAX, and SDHAF2 as susceptibility genes.

17 e, nonsynonymous variants in 99 sudden death-susceptibility genes.

18 come of genetic interaction between multiple susceptibility genes.

19 , and ASAH1 as candidate Parkinson's disease susceptibility genes.

20 germline mutations occurred in eight PCC/PGL susceptibility genes.

21 and loss of Sema3d, two Hirschsprung disease susceptibility genes.

22 TGCT and provide evidence for CMGs as cancer susceptibility genes.

23 ulation of many highly coexpressed human ASD-susceptibility genes.

24 which is one of the most well studied asthma susceptibility genes.

25 ed to evaluate the functional relatedness of susceptibility genes.

26 l virulence by activating expression of host susceptibility genes.

27 a helpful approach in the search for disease susceptibility genes.

28 ne-sets were novel and previously identified susceptibility genes.

29 (n = 16) of transcription factors among SLE susceptibility genes.

30 n studies (GWASs) to identify additional VTE susceptibility genes.

31 ansporters were significantly enriched among susceptibility genes.

32 ich environmental factors interact with AITD susceptibility genes.

33 , such as BRCA1, RAD51, and Fanconi's anemia susceptibility genes.

34 iological mechanisms and for mapping disease susceptibility genes.

35 pecific phenotyping in the search for asthma susceptibility genes.

36 tions that modulate expression levels of SLE susceptibility genes.

37 al variation in response to RSV and identify susceptibility genes.

38 with a pathogenic variant in 1 of 18 cancer susceptibility genes.

39 no other candidate high-penetrance melanoma susceptibility genes.

40 It also identified several other candidate susceptibility genes.

41 testing for BRCA1/2 and other ovarian cancer susceptibility genes.

42 onal individuals who lack mutations in known susceptibility genes.

43 ability of 74% motivated the search for ADHD susceptibility genes.

44 splicing datasets containing several cancer-susceptibility genes.

45 of expression of synaptic and schizophrenia-susceptibility genes.

46 Breast cancer susceptibility gene 1 (BRCA1) is a breast and ovarian ca

47 Breast cancer susceptibility gene 1 (BRCA1) is a tumor suppressor prot

48 vels of the exosome pathway regulators tumor susceptibility gene 101 (TSG101) and Ras-related protein

49 Tumour susceptibility gene 101 (TSG101) sorts TCRs for inclusio

50 an unbiased shRNA screen that revealed tumor susceptibility gene 101 (TSG101), a component of the end

51 cised mice, we observed that levels of tumor susceptibility gene 101 (Tsg101), a key member of the en

52 ous germline mutation in a pancreatic cancer susceptibility gene; 345 met family history criteria for

53 pecific deletion of the rheumatoid arthritis susceptibility gene A20/Tnfaip3 in mice (A20(myel-KO) mi

54 d evidence that coding variants in the known susceptibility gene ABCA7, as well as candidate genes DY

55 More studies are needed to identify host susceptibility genes along with confirmation from functi

56 It is now appreciated that pancreatic susceptibility gene alterations are often identified in

57 arepsilon3/4 and another Alzheimer's disease susceptibility gene and demonstrate in proof of principl

58 sults confirm PALB2 as a major breast cancer susceptibility gene and establish substantial associatio

59 n summary, this study reveals DLST as a PPGL-susceptibility gene and further strengthens the relevanc

60 inding protein 2 (IRP2) as an important COPD susceptibility gene and have shown that IRP2 protein is

61 vious implication of Del-1 as a candidate MS susceptibility gene and suggest that Del-1-centered ther

62 We identified 281 candidate susceptibility genes and bioinformatics analyses reveale

63 enetic studies are warranted to identify new susceptibility genes and clarify the genetic bases of dy

64 o support the notion that ethnicity-specific susceptibility genes and process are involved in the pat

65 -specific transcriptional activators of host susceptibility genes and sometimes resistance genes.

66 icrobe intersection, notably several disease susceptibility genes and sterol metabolism pathway compo

67 evolution of emerging strains, activation of susceptibility genes and strategies of host evasion.

68 AD51C and RAD51D are moderate ovarian cancer susceptibility genes and suggest that they confer levels

69 olase 2 (EPHX2) was identified as a novel AN susceptibility gene, and because its protein product, so

70 eptor, muscarinic 2, cardiac) as a candidate susceptibility gene, and mouse strains with a nonsynonym

71 sed by driver germline mutations in 16 known susceptibility genes, and approximately half of these ge

72 play among the immune system, keratinocytes, susceptibility genes, and environmental factors.

73 vestigated the expression patterns of 24 T2D-susceptibility genes, and their individual transcript va

74 However, newly identified COPD susceptibility genes are already providing novel insight

75 sion Germline mutations in pancreatic cancer susceptibility genes are commonly identified in patients

76 Obesity susceptibility genes are highly expressed in the brain s

77 ASD susceptibility genes are interconnected at the level of

78 Other neuroblastoma susceptibility genes are likely hidden among signals dis

79 Susceptibility genes are necessary but not sufficient to

80 o 9% of all cases of thyroid cancer, but the susceptibility genes are not known.

81 ies identified over half of the HSCR disease susceptibility genes as targets for the sex-determining

82 PrimPol has been reported to be a potential susceptibility gene associated with the development of m

83 nables rapid mutation screening for multiple susceptibility genes at once, suggesting that routine cl

84 locus (eQTL) analyses can identify candidate susceptibility genes at risk loci.

85 FANCC, has been proposed as a breast cancer susceptibility gene based on epidemiological and sequenc

86 m, regulatory pathways interconnecting human susceptibility genes, biomarkers, proteomes, and transcr

87 uals who have mutations in the breast-cancer-susceptibility gene BRCA1 (hereafter referred to as BRCA

88 we address the function of the breast cancer susceptibility gene Brca1 in meiotic silencing and recom

89 The breast cancer susceptibility gene BRCA1 is well known for its function

90 Pathogenic mutations in breast cancer susceptibility genes BRCA1 and BRCA2 increase risks for

91 The cloning of the breast cancer susceptibility genes BRCA1 and BRCA2 nearly two decades

92 response such as mutations in breast cancer susceptibility genes BRCA1 and BRCA2, and homologous rec

93 Breast and ovarian cancer susceptibility genes BRCA1 and PALB2 have enigmatic role

94 ethylene glycols selective for breast cancer susceptibility gene (BRCA1) is reported.

95 Mutations in breast cancer susceptibility genes (BRCA1 and BRCA2) are associated wi

96 tentially harmful mutations in breast cancer susceptibility genes (BRCA1 or BRCA2).

97 elected splice variants of the breast cancer susceptibility gene, BRCA1, can be monitored at single-c

98 ch affected known familial pancreatic cancer susceptibility genes: BRCA2 (12 patients), ATM (10 patie

99 LMO1 is a high-risk neuroblastoma susceptibility gene, but how LMO1 cooperates with MYCN i

100 of Xanthomonas exploit a single host disease susceptibility gene by altering the expression of an oth

101 e we set out to identify new high-penetrance susceptibility genes by sequencing 184 melanoma cases fr

102 n drug targets, somatic mutants, and disease susceptibility genes by utilizing directionality and pat

103 tential driver of AS and identified a new AS susceptibility gene, CACNA1C, belonging to the calcium s

104 ion of a single, widely expressed arrhythmia-susceptibility gene can generate a multisystem syndrome

105 functional evidence, we identify several PD susceptibility gene candidates for further investigation

106 We also obtained strong evidence for a new susceptibility gene, CDHR3 (encoding cadherin-related fa

107 functional genes indicates that most cancer susceptibility genes classified into these subgroups do

108 Here we focus on the schizophrenia susceptibility gene DTNBP1 and its product dysbindin, a

109 erturbations downstream of the schizophrenia susceptibility gene DTNBP1 confer susceptibility to copp

110 sociated with mutations in the schizophrenia susceptibility gene dysbindin (dysb), in isolation or in

111 exon-level RNA-Seq, and identified novel SLE susceptibility genes (e.g. NADSYN1 and TCF7) that were c

112 In addition to replicating previously known susceptibility genes (e.g., CDYL2, MST1R, GPER1, and PAR

113 diverse human LCLs enable identification of susceptibility genes (e.g., MX1) for RSV disease severit

114 for assessing the functional relatedness of susceptibility genes, either coding or noncoding, accord

115 Several known breast cancer susceptibility genes encode proteins involved in DNA dam

116 TRAF3IP2 is a candidate psoriasis susceptibility gene encoding Act1, an adaptor protein wi

117 in mice have provided evidence for multiple susceptibility genes, few of these have been confirmed f

118 Complement factor H (CFH) is a major susceptibility gene for age-related macular degeneration

119 ells 2 (TREM2) gene is a recently identified susceptibility gene for Alzheimer's disease (AD), as its

120 ariant of apolipoprotein E (APOE4), the main susceptibility gene for Alzheimer's disease(11-14), lead

121 ses = 0.0143, MAFcontrols = 0.0089), a known susceptibility gene for Alzheimer's disease.

122 Previously, PTPN22 was described as a susceptibility gene for autoimmunity because it contains

123 We identify WNT7B as a novel susceptibility gene for axial length (rs10453441, Pmeta=

124 AD1L1 (mitotic arrest deficient-like 1) as a susceptibility gene for bipolar disorder and schizophren

125 These data suggest that IL37 is a new susceptibility gene for CAD, which provides a potential

126 Our study supports ISL1 as a major susceptibility gene for CBE and as a regulator of urinar

127 surface molecule HAVCR1/KIM-1 is a suggested susceptibility gene for ccRCC and ectodomain shedding of

128 end products (RAGE) has been identified as a susceptibility gene for chronic obstructive pulmonary di

129 Although SERPINE2 is a candidate susceptibility gene for chronic obstructive pulmonary di

130 values and identified folliculin (FLCN) as a susceptibility gene for diabetic retinopathy.

131 reased lung tissue expression of SERPINE2, a susceptibility gene for emphysema.

132 We identify IL33 as an epithelial susceptibility gene for eosinophilia and asthma, provide

133 Our results suggested that MICALL2 is a new susceptibility gene for executive inhibition deficiency

134 Our findings suggest that POT1 is a major susceptibility gene for familial melanoma in several pop

135 t of this autoimmune response, is also a key susceptibility gene for GD, probably acting through thym

136 EF-hand calcium binding domain 14 as a novel susceptibility gene for HIV-1 acquisition.

137 ecruitment domain family member 9 (CARD9), a susceptibility gene for inflammatory bowel disease (IBD)

138 ger, has recently been identified as a novel susceptibility gene for inflammatory bowel disease (IBD)

139 The identification of AKAP13 as a susceptibility gene for IPF increases the prospect of su

140 We identified Acer2 as a first susceptibility gene for lithium-induced diabetes insipid

141 lity genes, including OBFC1, a new candidate susceptibility gene for low-grade and borderline serous

142 ain expressed protocadherin 17 (PCDH17) as a susceptibility gene for major mood disorders.

143 se transporter gene OsSWEET13 as the disease-susceptibility gene for PthXo2 and the existence of cryp

144 he aim of this study was to identify a novel susceptibility gene for SCAD.

145 tor protein (NOS1AP), a protein encoded by a susceptibility gene for schizophrenia.

146 Disrupted-in-Schizophrenia 1 (DISC1) is a susceptibility gene for several psychiatric illnesses.

147 These studies implicate DNER as a susceptibility gene for T2DM in American Indians.

148 NFIL3 is a susceptibility gene for the human inflammatory bowel dis

149 Clec16a has been identified as a disease susceptibility gene for type 1 diabetes, multiple sclero

150 or of mitophagy and has been identified as a susceptibility gene for type 2 diabetes (T2D).

151 One of the strongest susceptibility genes for age-related macular degeneratio

152 Nedd4l, Ano6, and Rnf220 are candidate susceptibility genes for AgNP-induced lung inflammation

153 ered DPP4, TRHR, and MLF1 as novel candidate susceptibility genes for ASD in the Lebanese.

154 Many of the identified susceptibility genes for asthma are expressed in the air

155 We aim to identify susceptibility genes for asthma combined with BHR and an

156 Susceptibility genes for asthma, AR and AD have now been

157 We aimed to identify additional susceptibility genes for CAVS.

158 Success has been more limited in mapping susceptibility genes for clusters of cardiovascular risk

159 nalysis of the infected brain: We identified susceptibility genes for congenital toxoplasmosis in our

160 in mice can be used successfully to identify susceptibility genes for development of lithium-induced

161 terations modulated by both inflammation and susceptibility genes for diabetes contribute to beta cel

162 ir receptors, ERBBs, have been identified as susceptibility genes for diseases such as schizophrenia

163 Other susceptibility genes for familial forms of MNG likely ex

164 study regions, identifying 23 new candidate susceptibility genes for HGSOC.

165 We sought to identify susceptibility genes for high-grade serous ovarian cance

166 cytes bearing apoptotic IECs overlapped with susceptibility genes for inflammatory bowel disease.

167 icated BATF3, CCDC88B and CIITA-SOCS1 as new susceptibility genes for leprosy.

168 To identify susceptibility genes for lithium-induced adverse effects

169 ology of synapses in patient neurons and how susceptibility genes for mental disorders could lead to

170 To identify susceptibility genes for osteoporosis, we conducted an i

171 ngs are consistent with Notch3 and Notch4 as susceptibility genes for ozone-induced lung injury, and

172 In the past decade, the identification of susceptibility genes for psychiatric disorders has becom

173 of the most prominent and highly replicable susceptibility genes for several neuropsychiatric disord

174 for relative prenatal enrichment of putative susceptibility genes for syndromic neurodevelopmental di

175 However, the identification of definitive susceptibility genes for these etiologically complex dis

176 Cs (hESCs) with mutations in GWAS-identified susceptibility genes for type 2 diabetes.

177 of Exome Sequencing for Head and Neck Cancer Susceptibility Genes, Genetic Epidemiology of Chronic Ly

178 a splicing factor regulated by the diabetes susceptibility gene GLIS3, has a major role in maintaini

179 interacts with YIN YANG1 to suppress disease susceptibility genes glutaredoxins GRX480, GRXS13 and th

180 found that participants bearing mutations in susceptibility genes had significantly lower adaptive ab

181 However, the identification of robust PD susceptibility genes has been complicated by phenotypic

182 ons in BRCA1, BRCA2, and other breast cancer susceptibility genes has since proved to be a valuable t

183 Although 16 LQTS-susceptibility genes have been discovered, 20% to 25% of

184 arrying pathogenic variants of common cancer susceptibility genes have yet to be identified.

185 here current knowledge about functions of AD susceptibility genes, highlighting cells of the myeloid

186 Among the shared susceptibility genes, HLA-DRbeta1-Arg74 (human leukocyte

187 Human SEMAPHORIN 5A (SEMA5A) is an autism susceptibility gene; however, its function in brain deve

188 as a 50-60% risk contribution from inherited susceptibility genes; however, their exact identity and

189 is study demonstrates that ORMDL3, an asthma susceptibility gene identified by genome-wide associatio

190 Finally, cardiovascular disease susceptibility genes identified using public genome-wide

191 Breast cancer susceptibility gene II (BRCA2) is central in homologous

192 gical parameters in laboratory mice carrying susceptibility genes implicated in inflammatory bowel di

193 Many ASD susceptibility genes implicated in neuronal pathways/bra

194 olog B) was first identified as a metastasis susceptibility gene in breast cancer through its ability

195 fied as a gastrointestinal (GI) tract cancer susceptibility gene in multiple Sleeping Beauty DNA tran

196 xenograft model, we identify EPB41 as a HCC susceptibility gene in vitro and in vivo.

197 cross 90% of nucleotides within sudden death-susceptibility genes in 100% of parental exomes from fre

198 ns were identified in 12 of 25 breast cancer susceptibility genes in 26 families without identified B

199 lies and prioritized top potential candidate susceptibility genes in our dataset.

200 Current testing guidelines for germ line susceptibility genes in patients with breast carcinoma w

201 f pathogenic variants (PVs) in breast cancer susceptibility genes in postmenopausal women with vs wit

202 ALEs) that activate transcription of disease susceptibility genes in the host, inducing a state of di

203 32 genes, including known pancreatic cancer susceptibility genes, in DNA prepared from normal tissue

204 n or near previously identified osteoporosis susceptibility genes including ESR1 (6q25.1: rs4869739,

205 nant mutations in adult and pediatric cancer susceptibility genes (including 2 each in TP53, VHL, and

206 iofeatures at each locus predicted candidate susceptibility genes, including OBFC1, a new candidate s

207 studies (GWASs) have identified hundreds of susceptibility genes, including shared associations acro

208 However, most arrhythmia-susceptibility genes, including the KCNE2 K(+) channel b

209 ession of CR1 (complement receptor 1), an AD susceptibility gene involved in immune pathways, uniquel

210 The main high-penetrance melanoma susceptibility gene is CDKN2A, encoding p16INK4A and p14

211 n profile of specific transcripts of disease-susceptibility genes is for the first time described in

212 1, early onset), a well-known breast cancer susceptibility gene, is a highly alternatively spliced g

213 ional analysis of the major long-QT syndrome-susceptibility genes (KCNQ1, KCNH2, and SCN5A) and catec

214 genetic testing of the 4 major channelopathy-susceptibility genes (KCNQ1, KCNH2, SCN5A, and RYR2) hav

215 .8) with that of the previously suggested DD susceptibility genes KIAA0319, CTNND2, CNTNAP2 and GRIN2

216 -wide association study aims to identify the susceptibility gene loci for excessive alcohol consumpti

217 gene encoding kinesin family member 3A, is a susceptibility gene locus associated with asthma; howeve

218 ntia have identified an increasing number of susceptibility genes, many of which are poorly character

219 shed light on the specific tissues in which susceptibility genes might exert their functions.

220 erse a paradoxical association of the strong susceptibility gene MUC5B with increased survival, sugge

221 a previously unrecognized pancreatic cancer susceptibility gene mutation (nine that involved ATM, tw

222 termine the frequency and spectrum of cancer susceptibility gene mutations among patients with early-

223 Conclusion Germline cancer susceptibility gene mutations are carried by 9.9% of pat

224 risk, yet the prevalence of germline cancer susceptibility gene mutations in patients with CRC unsel

225 stimation of carrier probabilities of cancer susceptibility gene mutations is an important part of pr

226 These deleterious pancreatic cancer susceptibility gene mutations, some of which are therape

227 e findings identify FANCM as a breast cancer susceptibility gene, mutations in which confer a particu

228 of the validated genes connect to a known AD susceptibility gene network.

229 hocking incident, but the underlying disease susceptibility gene networks remain poorly understood.

230 otects mice deficient in the Crohn's disease susceptibility gene Nod2 from intestinal abnormalities b

231 i mapping in human valve tissues to identify susceptibility genes of AS.

232 Because NRG1 and ErbB4 are susceptibility genes of schizophrenia, our findings migh

233 Considering that both NRG1 and ErbB4 are susceptibility genes of schizophrenia, our study sheds l

234 nderwent germline DNA sequencing of a cancer susceptibility gene panel.

235 have led to the development of breast cancer susceptibility gene panels for germline genetic testing

236 Our findings identify that the asthma susceptibility gene product CDHR3 mediates RV-C entry in

237 We propose that polymorphisms in susceptibility genes promote disease through defects in

238 lymorphisms that prevent effector binding to susceptibility gene promoters, or that allow effector ac

239 pathway clusters activated by PHEO- and PGL-susceptibility genes: pseudohypoxic, kinase, and Wnt sig

240 The retinoblastoma susceptibility gene (RB1) was the first tumor suppressor

241 hat autophagy and inflammatory bowel disease susceptibility genes regulate inflammatory responses to

242 Dysbindin is a schizophrenia susceptibility gene required for the development of dend

243 minergic polymorphic ventricular tachycardia-susceptibility gene (RYR2) identified a putative pathoge

244 Our findings extend the list of susceptibility genes shared with Crohn's disease and lep

245 riant near GRN, another TDP-43 proteinopathy susceptibility gene, shows concordant effects with the T

246 ed ASD genes and uncover novel inherited ASD susceptibility genes specific to the Lebanese.

247 A novel susceptibility gene, ST13, coding for a cochaperone of t

248 N2A, CDK4, and BAP1) and intermediate (MITF) susceptibility genes; statistical effect of histologic s

249 ions in breast tumors to known breast cancer susceptibility genes such as BLM (1.9%) and LSP1 (0.3%).

250 ategorized as an hypertrophic cardiomyopathy susceptibility gene, such that a mouse model can recapit

251 isk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mo

252 resence of prenatal expression enrichment of susceptibility genes systematically, as composite gene s

253 There is indication that susceptibility genes tend to be expressed in the brain d

254 ous germline mutation in a pancreatic cancer susceptibility gene than it is among individuals with a

255 ATM is an important cancer susceptibility gene that encodes a critical apical kinas

256 transcriptional cofactor, as a neuroblastoma susceptibility gene that functions as an oncogene in hig

257 stemic autoimmunity and that FAAH is a lupus-susceptibility gene that might regulate this process.

258 y common regulatory elements and predict new susceptibility genes that are biologically meaningful to

259 to carcinogenesis through the regulation of susceptibility genes that are related to the biogenesis

260 evelopmental in etiology are associated with susceptibility genes that are relatively upregulated dur

261 Synapsins are epilepsy susceptibility genes that encode phosphoproteins reversi

262 We identified 20 potential schizophrenia susceptibility genes that encode proteins that are the t

263 virulence factors of Liberibacters serve as susceptibility genes that facilitate compatibility (e.g.

264 is also evidence suggesting the existence of susceptibility genes that predispose chronically stresse

265 pproach, we identified several new candidate susceptibility genes that warrant future investigations

266 IDE (insulin-degrading enzyme) as a diabetes susceptibility gene, the relationship between the activi

267 KN2A is the most frequent high-risk melanoma susceptibility gene, the underlying genetic factors for

268 igm is expected to apply to other arrhythmia-susceptibility genes, the majority of which encode ubiqu

269 .3 and SEMA3A as a possible Brugada syndrome susceptibility gene through a Kv4.3 gain-of-function mec

270 s in genes in the steroid pathway and asthma susceptibility genes to exacerbations in children and yo

271 nogaster model system can identify candidate susceptibility genes to guide subsequent studies in huma

272 oglia, including complement, phagocytic, and susceptibility genes to neurodegeneration, such as Alzhe

273 etes in restricted lines of inbred mice, the susceptibility genes to virus-induced diabetes have not

274 anisms by which the expression of epithelial susceptibility genes translates into a functionally alte

275 oallelic germline mutations in breast cancer susceptibility gene type 1 or 2 (BRCA1/2) poses tissue-s

276 results suggest that ADAM12 gene is a novel susceptibility gene underlying both joint destruction an

277 R can evaluate the functional relatedness of susceptibility genes underlying schizophrenia and breast

278 TIONALE: Genetic polymorphisms in the asthma susceptibility gene, urokinase plasminogen activator rec

279 ne DNA was tested for mutations in 25 cancer susceptibility genes using next-generation sequencing.

280 Admission to the NICU in those without the susceptibility gene variant at rs17815905 (LOC283710/KLF

281 particular, breast-feeding in those with the susceptibility gene variant at rs6736278 (CAPN14) reduce

282 ncer with a known germline pathogenic cancer susceptibility gene variant should be offered individual

283 Overall, 17 sudden death-susceptibility gene variants were identified in 12 of 28

284 n quantitative trait loci (eQTL) to identify susceptibility genes/variants from multiple GWAS loci.

285 that expression levels of 33 and 66 putative susceptibility genes were associated with specific mutat

286 Germline findings in cancer susceptibility genes were concordant with the individual

287 ous and splice-site variants in 2 arrhythmia susceptibility genes were identified in 223 individuals

288 Nine candidate FSGS susceptibility genes were identified in our patient coho

289 for mutations in other breast/ovarian cancer susceptibility genes when these genes are analyzed as a

290 reported low- to moderate-risk breast cancer susceptibility gene, which may also interact with ERCC8.

291 e existence of further major high-penetrance susceptibility genes, which individually account for >1%

292 Genetic analyses have reported numerous BD susceptibility genes, while some variants, such as singl

293 cal member of the Bcl-2 family, as a therapy susceptibility gene with elevated expression in solid an

294 d molecular mechanisms connecting a disorder susceptibility gene with environmental factors remain mo

295 to 85% of those may be due to segregation of susceptibility genes with low and moderate risk [odds ra

296 diseases, suggesting the involvement of many susceptibility genes with small effect sizes.

297 0L as a candidate familial Barrett esophagus susceptibility gene, with a putative role in maintaining

298 ystematically search for schizophrenia (SCZ) susceptibility genes within 49 genomic loci previously i

299 iduals with pathogenic variants in 18 cancer susceptibility genes would be 46.2, 22.3, 13.6, and 9.9

300 n explained by risk alleles at the psychosis susceptibility gene ZNF804A and its interacting partners