ライフサイエンスコーパス: sustain

1 occur on the Mexican Pacific coast cannot be sustained.

2 in which transmission is too low to be self-sustaining.

3 t in source-sink dynamics: one community can sustain a micro-epidemic in another community in which t

4 AT and other organ thermogenesis; and how to sustain a negative energy balance over many years of tre

5 The boy had sustained a bicycle handlebar injury to his upper abdome

6 days for surgery, and determined the odds of sustaining a fall within 90 days of biometry among patie

7 hip is different between sexes, with females sustaining a greater relative intensity of exercise.

8 tudy letters from baseline, as well as first sustained absence of retinal fluid and intraretinal flui

9 Interestingly, 5-ITu causes sustained accumulation of p53, increases markedly the ex

10 a clade of organisms can be explained by the sustained action of natural selection or by a high mutat

11 The persistent population displayed sustained activation following visual cue presentation,

12 g in organoids, in part through elevated and sustained activation of mitogen-activated protein kinase

13 lly depends on autocrine IL-3 acting via the sustained activation of STAT5 on the expression of IL-9.

14 ning, and (c) ability of the institutions to sustain activities deemed to be beneficial.

15 xemia and that Zip14 ablation coincides with sustained activity of phosphorylated components of signa

16 ing protein (GAP), providing a mechanism for sustained activity of the RAS ITD protein.

17 ents who responded to lithium; they featured sustained activity with large current injections and a l

18 Such effects likely contribute to its sustained AD-like activity.

19 nistration of NBQX into the mPFC blocked the sustained AD-like effect of L-655,708.

20 p) were followed for 3 weeks: sustained AFL; sustained AF (600 beats/min atrial tachypacing); AF supe

21 Sustained AFL causes atrial repolarization changes like

22 6 dogs per group) were followed for 3 weeks: sustained AFL; sustained AF (600 beats/min atrial tachyp

23 tio, 0.30; 95% CI, 0.22 to 0.42) and was not sustained after that time (week 15 through week 26) (haz

24 The reduction in AIR was also sustained after the first examination (P < .001 to P = .

25 Sero-protection was estimated to be sustained against H1N1pdm09 but to wane by 8-months for

26 Animal-mediated pollination is critical for sustaining agricultural economies and biodiversity, yet

27 The role of microbes in sustaining agricultural plant growth has great potential

28 of indicator compounds were used to isolate sustained air pollution "events".

29 a2+]i dynamics observed experimentally after sustained alkalinisation can be reproduced by a model fe

30 [i.e., the CO(2) fertilization effect (CFE)] sustains an important negative feedback on climate warmi

31 IRT3-dependent increases in SOD2 mRNA during sustained anchorage-independence.

32 ficacy benefits with fixed-duration VenR are sustained and particularly durable in patients who achie

33 survival Tasmanian Gondwanan species demands sustained and targeted fire management.

34 o the skin, implanted thin films facilitated sustained and temporal release of individual vaccine com

35 g tool called "Subtype and Stage Inference" (SuStaIn) and to evaluate the utility of SuStaIn for pati

36 osteric modulator, L-655,708, reproduces the sustained antidepressant-like (AD-like) effect of R,S-ke

37 f GS-9688 is well tolerated and can induce a sustained antiviral response in WHV-infected woodchucks;

38 signals, these neurons produce aversive and sustained appetite-suppressing signals, which discourage

39 se in type 3 cytokines with type 2 mediators sustained at high levels.

40 duration <0.2 s) to a persistent motor that sustains attachment (median attachment duration >3 s) at

41 -theanine, caffeine and their combination on sustained attention, inhibitory control and overall cogn

42 excluded practices that did not implement or sustain behavioral health integration, potentially limit

43 tory infections, but data are conflicting on sustained benefits after intervention discontinuation.

44 nd continuous ocrelizumab treatment provided sustained benefits on measures of disease progression ov

45 of breastfeeding, and the low prevalence of sustained breastfeeding in this study and Australia in g

46 mers also applied to the steady-state, since sustained Btnl expression is required to maintain the si

47 vents whose biogeochemical consequences were sustained by a set of positive feedbacks, mediated by th

48 ased phytoplankton biomass, which was likely sustained by an influx of new nutrients.

49 success of cattle herding in Africa has been sustained by dynamic food systems, consumption of a broa

50 reatening lupus, with the clinical responses sustained by maintenance therapy with belimumab, an anti

51 chemoattractant synthesis is triggered by a sustained calcium flux upon contact with necrotic tissue

52 types that engage in a dynamic interplay to sustain cancer-specific signaling networks.

53 multivesicular bodies (MVBs) is required for sustained canonical Wnt signaling.

54 t of plant growth and the ecosystem became a sustained carbon sink well before winter ended, taking u

55 Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in clinical practice and is

56 Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is associated with substan

57 nation prior to a planned withdrawal of life-sustaining care in an imminently dying patient.

58 stress acclimation, and the consequences of sustained CEF in UWO 241 are not known.

59 ino acid source by activating endocytosis to sustain cell proliferation and survival.

60 UBR5 is also required to sustain cell-intrinsic beta-catenin-mediated signaling t

61 Sustained cell migration is essential for wound healing

62 s superior to annual treatment for achieving sustained clearance of Onchocerca volvulus MF from the s

63 n participants with hemophilia A resulted in sustained, clinically relevant benefit, as measured by a

64 ed a controllable transgenic mouse line that sustains cortical MET signaling.

65 Irrigation plays an essential role in sustaining crop production in water-limited regions, as

66 y trace interval of several seconds requires sustained cue-elicited firing in the prelimbic cortex (P

67 ing all men and women to DTG would lead to a sustained decline in resistance levels, whereas using DT

68 This substantial and sustained decrease in tumour volume suggests that the pr

69 upporting the use of complex coacervates for sustained delivery of immunostimulatory proteins as an e

70 lso resolved their acute AMR episode and had sustained disappearance of circulating DSA for <=30 mont

71 SSCT with allogeneic donor stem cells led to sustained donor-derived spermatogenesis.

72 Besides sustained drug delivery, AFL-assisted powder reservoir p

73 respect to incorrect ones, and that this is sustained during the entire trial.

74 ranscriptome, the pathways and networks that sustain EC heterogeneity have not been fully delineated.

75 GB001 may have a rapid and sustained effect on lung function, particularly in patie

76 Replicating prior work, sustained effects associated with autobiographical recal

77 ed stringent suppression measures as well as sustained efforts to target those at highest risk becaus

78 ources away from internal pH upregulation to sustain elevated tissue growth, resulting in a porous an

79 Moreover, pharmacologically sustained elevation of zinc in WT eggs prior to activati

80 ous Violence: Hurting and Killing to Create, Sustain, End, and Honor Social Relationships (2014)], wh

81 describe the ability of host populations to sustain endemic infectious disease.

82 ng these sensors, we showed that EGF induces sustained ERK activity near the plasma membrane in sharp

83 n state, United States, founded the earliest sustained European and North America transmission networ

84 ens, such as influenza and measles, generate sustained exponential growth in incidence and have a hig

85 ng that loss of ARF strongly correlates with sustained expression of inflammatory and cell survival p

86 Pdap1 deficiency leads to sustained expression of the integrated stress response (

87 population activity through its powerful and sustained feedforward inhibition.

88 GCs) had higher firing thresholds and could sustain firing with larger current inputs than GCs close

89 Individual interneurons did not display sustained firing but instead transiently enhanced their

90 icular to an interface and develop into self-sustained flow convection cells.

91 driven energy conservation during winter and sustaining foetal growth, which may also apply to other

92 ce" (SuStaIn) and to evaluate the utility of SuStaIn for patient stratification in COPD.Methods: We a

93 e aerobic exercise on inhibitory control are sustained for 60 min in children with ADHD.

94 ) 0%, p=0.80) in 16 studies, particularly if sustained for more than 1 year (crude OR 0.62, 0.47-0.81

95 These parameters were consistently sustained for over 1 year after the 6-week optimization.

96 erties and preserved protein binding able to sustain, for over six weeks in vivo, the localized activ

97 y characterized photoprotection mechanism, a sustained form of nonphotochemical quenching (sustained

98 Sustaining Foxp3-transcriptional activation in induced T

99 , improvements in mNIS+7 with patisiran were sustained from parent study baseline with treatment in t

100 erein, we present a polymeric NP system with sustained gene delivery properties, which can be synthes

101 s in colder regions such as the Arctic under sustained global warming, but with complex and not neces

102 3.6 Ma) is the most recent past interval of sustained global warmth with mean global temperatures ma

103 Sustained gluten exposure reliably induces histologic ch

104 hort course of rapamycin regimen resulted in sustained graft survival and function in >90% of allogen

105 Included are a batch culturing system for sustained growth of subject-specific gut microbial commu

106 Although Hodor sustains gut luminal acidity and restrains microbial loa

107 Unexpectedly, sustained H3K36me3 deposition is dependent on HP1gamma.

108 gin of the GBM resection cavity to provide a sustained high local dose with reduced systemic toxiciti

109 istic intermediate dynamics distinguished by sustained high spindle activities.

110 ally, we demonstrate that ACh contributes to sustaining high discharge rates and enhances signal enco

111 mon coinfections, such as herpesviruses, may sustain HIV tissue reservoirs during suppressive ART, su

112 cued AnxA6(-/-) mice survival after PHx, the sustained hypoglycemia in partially hepatectomized AnxA6

113 ercapnia or after the exposure to short-term sustained hypoxia.

114 by 58%, which is comparable to control rats sustaining I/R injury.

115 the achievement of cure in RA by triggering sustained immune activation and effector cytokine produc

116 nary data argued in favor of substantial and sustained immune pressure exerted upon a developing tumo

117 overy are associated with distinct early and sustained immunologic and endothelial biomarker signatur

118 RUX cream provided rapid and sustained improvements in AD symptoms and was well toler

119 Higher baseline CRF and sustained improvements in CRF and weight loss were assoc

120 Nemolizumab resulted in rapid and sustained improvements in cutaneous signs of inflammatio

121 Medication reduction was sustained in 187 (66.3%) participants at 12 weeks.

122 r limit to the number of species that can be sustained in stable equilibrium by an ecosystem.

123 global value maximum signals are delayed and sustained in the AH body.

124 to understanding how cone-mediated vision is sustained in vivo.

125 A sustained increase in intracellular Ca(2+) concentration

126 An additional sustained increase in NOD1 abundance to 1.5-fold over ba

127 se in DAG levels, unlike the robust and more sustained increase induced by muscarinic receptor activa

128 s or their bone marrow progenitors, mediates sustained increased responsiveness to secondary challeng

129 nt adenosinergic signalling, which serves to sustain inflammasome activation and worsen fibrotic reac

130 e covalent inhibitor, compound 15a exhibited sustained inhibition of SRC signaling both in vitro and

131 Failing to sustain intensive surveillance during the later phases o

132 ritical thickness beyond which the otherwise sustained interfacial reactions are arrested.

133 s underlines the importance and potential of sustained intervention regarding the skin pH and urges f

134 Molecular oxygen (O(2)) sustains intracellular bioenergetics and is consumed by

135 glaucoma provides effective IOP reduction or sustained IOP control and meaningful medication reductio

136 logy of innate immunity and to determine how sustained ISG upregulation can be compatible with robust

137 tion to the aptitude of the pneumococcus for sustaining its human reservoir.

138 Our results not only suggest that many pools sustain juvenile salmon in non-drought years transition

139 variations that perpetuate as adaptations to sustain life.

140 bled 4CL5 catalysis at a level sufficient to sustain lignification.

141 atterns of disease progression in COPD using SuStaIn, likely representing different endotypes.

142 s an intrinsic castration-resistant and self-sustained lineage that emerges early during prostate dev

143 ntrations at some sites are primarily due to sustained local emissions, while the low concentrations

144 tiple opportunities to rethink approaches to sustaining long-term critical research in the field, ult

145 the release of nucleic acid drug payload for sustained, long-term gene expression or silencing.

146 vaccination with a biennial disease pattern, sustained low rates of rotavirus in children < 3 years o

147 tivate the postsynaptic receptors generating sustained low-amplitude current and desensitize the rece

148 steroid allows for initial proliferation and sustained M. abscessus pulmonary infection and permits e

149 inducing anxiety in a simple, consistent and sustained manner.

150 pulation contributes to impede the spread of sustained measles epidemics, rather than favoring it.

151 nt of cat ffEVs and their potential roles in sustaining meiotic competence of cryopreserved oocytes.

152 In contrast, sustained mesoaccumbal inactivation greatly reduced moti

153 ary genes responsible for maintaining a life-sustaining metabolic balance.

154 or that transmits intracellular signals that sustain microglial responses during Alzheimer's disease.

155 hting the vital role of stopover habitats in sustaining migratory communities.

156 es, the function(s) of lysosomes required to sustain mitochondrial health remains unclear.

157 The primary end point was a sustained molecular response in the bone marrow after th

158 findings led to a more recent proposal that sustained MOR signaling caused analgesic tolerance.

159 , we found that flies, like humans, perceive sustained motion in the stationary gradients.

160 ates the effects of fibroblasts resulting in sustained MTOR signaling and poor lapatinib response.

161 by fibroblasts in tumor cells that exhibited sustained MTOR signaling due to a strong gain-of-functio

162 rowth beyond Ras-transformed tumor cells via sustained mTORC1 activation.

163 VID-19 to determine whether they develop and sustain multifaceted SARS-CoV-2-specific immunological m

164 jury secondary to the collateral damage from sustained myocardial inflammation within the infarct zon

165 uted to axon degeneration/neuronal death and sustained neuroinflammation.

166 Self-sustained Ni(I/III) cycles are established as a potentia

167 ustained form of nonphotochemical quenching (sustained NPQ).

168 ant NUE responses are likely insufficient to sustain observed greening trends in NGP grasslands in th

169 identified one of the involved cell types as sustained ON alpha-ganglion cells.

170 The beneficial effects of sustained or lifelong (>25 years) endurance exercise on

171 ence of de-novo ventricular arrhythmias (non-sustained or sustained ventricular tachycardia or ventri

172 lin and actin revealed residues critical for sustaining or abrogating the light- and stress-gated res

173 h, to implement comprehensive change that is sustained over decades, and scaled up into the entire gl

174 served that this enhanced lysosomal state is sustained over time and defines an adaptive homeostasis

175 se that is released from mitochondria during sustained oxidative stress.

176 Sustained P2RX7 signaling was required for long-term Trm

177 gical co-targeting of MEK1/2, HDAC3, and G9a sustains PDAC tumor growth inhibition in vivo.

178 These results demonstrate that sustained physiologic hyperglycemia for 72 h 1) increase

179 ploys comparatively glycolytic metabolism to sustain physiological citrate secretion, whereas prostat

180 studies also demonstrate the requirement for sustained PI supply from the ER for the maintenance of m

181 SuStaIn placed 30% of smokers with normal lung function

182 nd primordia patterning that results in self-sustained planar intercalations.

183 y driven by aeolian vibration, enabling self-sustained PM adhesion.

184 Nevertheless, self-sustaining populations of roach (Rutilus rutilus) inhabi

185 iEEG deconvolution revealed sustained positive responses to visual-only speech and l

186 Sustained postoperative surveillance for all patients is

187 nds and Maillard products are related to the sustained production of H(2)O(2) over time, which in tur

188 on in mice, leading to high mortality due to sustained production of pro-inflammatory cytokines.

189 and drought resilience in C(3) plants while sustaining productivity in the hotter and drier climates

190 Sustained proliferation is a significant driver of cance

191 of hepatic steatosis, and 4) evidence for a sustained protection against steatosis induced by exerci

192 patients, adverse event in 34 patients, and sustained quiescence in 25 patients.

193 More recently, it was proposed that sustained, rather than reduced, MOR signaling caused tol

194 and synovial fluid samples from 30 dogs that sustained RCCL and 9 clinically healthy dogs were analyz

195 receptor domain is responsible for the Fls3-sustained reactive oxygen species, suggesting involvemen

196 TNFR1 transport to cell membrane, leading to sustained receptor responsiveness and downstream NF-kapp

197 bstinence, alcohol-dependent patients showed sustained recovered mGluR5 availability in cortical and

198 U.S.-born residents was projected to produce sustained reductions in TB incidence.

199 ntly encapsulate nucleic acid cargo, exhibit sustained release of payload, and can stably transfect c

200 nstrate that membrane budding results in the sustained release of platelets directly into the periphe

201 neutrophil-mediated lung metastasis via the sustained release of Zileuton.

202 Additionally, sustained-release NP-EFs, administered 24 h prior to inf

203 tes achieved high GRFT loading, and provided sustained-release of GRFT for up to 90 d.

204 -electrospun fiber (EF) composite to provide sustained-release of GRFT, and to examine its safety and

205 Furthermore, we develop a slow sustained-release strategy to overcome the limited dispe

206 A majority of patients had sustained remissions.

207 itment of more complex mechanisms capable of sustaining repetitive activity, overcoming inhibitory me

208 This environment relies on sustained research support, commitment to providing the

209 ngaging 16-18-year-old A level biologists in sustained research.

210 l to ~15 months, most patients do not have a sustained response to treatment.

211 treatment is expected to achieve a rapid and sustained response, the response at a fixed time point d

212 ces of ~220 nN and pressures of ~5.6 kPa and sustained responses at higher forces of ~360 nN and pres

213 as expressed as the selective suppression of sustained responses to low-identity faces.

214 We tested whether fragmentation of sustained rest/activity patterns derived from actigraphi

215 pigmentosa, a lead compound, Q525, afforded sustained RET activation and prevented photoreceptor neu

216 We aimed to compare the health benefits of sustaining routine childhood immunisation in Africa with

217 mitter switching provides the basis by which sustained running benefits motor skill learning, present

218 tized S1P(1) These findings demonstrate that sustained S1P(1) activation can occur pharmacologically

219 d (AMPA) receptor plasticity plays a role in sustaining seizures, seizure generalization, and mortali

220 for blockade of Gsk3alpha/beta and Mek1/2 to sustain self-renewal of mESCs in combination with leukae

221 The induction of sustained sensitivity and nociception without joint dama

222 According to sustained sensitization in tiers 1 and 2, T cell-related

223 elucidate when, where, and how the earliest sustained severe acute respiratory syndrome coronavirus

224 nder Synechococcus poor primary producers to sustain shelf sea food webs efficiently.

225 ellular signalling, such as through tonic or sustained signalling after ligand engagement.

226 eleration, distance to goal, and licking) in sustained slow firing modulation.

227 reatment induces Socs1 m(6)A methylation and sustains SOCS1 induction by promoting Fto mRNA degradati

228 ls, but not PV+ cells, significantly reduces sustained spectral surround suppression in excitatory ce

229 neration of F-actin bundles required for the sustained stabilization of highly contractile actomyosin

230 These results signal the need for sustained stringent suppression measures as well as sust

231 Posttransplant, sustained suppression of 3 of 3, 4 of 6, and 8 of 8 DSA

232 to infection with B. burgdorferi resulted in sustained swelling, as well as histopathological changes

233 Specifically, superior sustained systemic and mucosal HIV Gag-specific poly-fun

234 t offers the promise of clean power for self-sustained systems(1,2).

235 ss during chronic T cell stimulation allowed sustained T cell proliferation and induced genes associa

236 major challenge for cancer immunotherapy is sustaining T-cell activation and recruitment in immunosu

237 and release of the depot coincided with the sustained TAF release.

238 re to Ags, such as chronic viral infections, sustained TCR signaling can result in T cell exhaustion

239 in developing mouse forelimbs, BCL9 proteins sustain the action of beta-catenin in a largely PYGO-ind

240 mmatory diseases, but most do not develop or sustain the diseases, suggesting that there exist regula

241 otypic variation will improve our ability to sustain the diversity of this tree through an unpredicta

242 ability of the bonds existing at any time to sustain the drag forces on the aggregate determines whet

243 ic stewardship program efforts is crucial to sustain the efficacy of antibiotics and quality of infec

244 simulations reveae metabolic exchanges that sustain the heterotrophs in minimal media devoid of any

245 similar trajectories across the lifespan or sustain the impacts of brain aging independently.

246 of a shield immunity strategy is to help to sustain the interactions necessary for the functioning o

247 n by the energy cost for the top material to sustain the polarization imposed upon it by the underlyi

248 Many grass crops that are vital to sustain the world's caloric intake are salt sensitive.

249 ha only are less effective in initiating and sustaining the activation of Rubisco than when Rca-beta

250 eling of the tumor microenvironment (TME) by sustaining the calcium transients and neurotransmitter-d

251 9 pandemic has placed a tremendous strain on sustaining the clinical research enterprise and will als

252 ortant contribution of local transmission in sustaining the epidemic, as well as a complex viral migr

253 and reproductive state-specific activity in sustaining the increased food intake of mothers during r

254 corneal innervation plays a pivotal role in sustaining the integrity of the ocular surface.

255 within otherwise highly motile T cells that sustains the symmetry and stability of the T cell-APC sy

256 h higher LBP and LBP:sCD14 were less able to sustain their attention throughout the entire CPT, as re

257 However, the mechanisms that sustain their production and recruitment to the injured

258 reefs will need high conservation status to sustain them close to dense human populations.

259 To achieve a sustained therapeutic efficacy and reduced toxicities, m

260 These reductions were sustained through to days 28 and 29 (p = 0.050 and p = 0

261 eosinophil subgroups, respectively) and were sustained through treatment completion.

262 have formed within days, if these rates are sustained throughout pegmatite formation.

263 reating residents of index households over a sustained time period could contribute to malaria elimin

264 These results suggest that BCL11A sustains TNBC cell invasion and metastatic growth by rep

265 t stratification in COPD.Methods: We applied SuStaIn to cross-sectional computed tomography imaging m

266 sm is exploited by tumor cells to aberrantly sustain transcriptional programs commonly dysregulated i

267 omous circadian clock is built around a self-sustaining transcriptional-translational negative feedba

268 The genetic data reflect sustained transmission within reservoir areas, further e

269 ess frequently use Physician Orders for Life-Sustaining Treatment (POLST) to document treatment limit

270 ic transformation alters lipid metabolism to sustain tumor growth.

271 data establish an unforeseen role of GLS2 in sustaining tumor proliferation and underlying metastasis

272 Cancer cells undergo metabolic adaptation to sustain uncontrolled proliferation.

273 on, reducing protein glycosylation, causes a sustained Unfolded Protein Response (UPR), a significant

274 Eighteen subjects underwent an optional sustained unresponsiveness assessment; 14 of those (77.8

275 in LNCaP tumor xenografts, and this peak was sustained up to 120 h after injection.

276 climate change mitigation, assuming primary, sustained use of LPG for daily cooking.

277 We found that sustained use over two weeks was accompanied by increase

278 ongoing safety assessments are important in sustaining vaccine uptake.

279 o lentiviral transfection was used to induce sustained VDR-KD in C2C12 cells to analyse myogenic regu

280 vo ventricular arrhythmias (non-sustained or sustained ventricular tachycardia or ventricular fibrill

281 t the treated failing heart is more prone to sustain VF than the normal heart, and is at least as sus

282 mal heart, and is at least as susceptible to sustained VF as the untreated failing heart.

283 e-ART, are the main features associated with sustained viral control after ATI in SIV-infected RMs.IM

284 Children <18 years at ART initiation, with sustained viral suppression (VS) (<=400 copies/mL) for >

285 in in 12 centers across Thailand to estimate sustained virologic response at post-treatment week 12 (

286 Sustained virologic response was high in nonadherent (89

287 treatment course, and 61 (50%) have achieved sustained virologic response.

288 HIV drug resistance (HIVDR) is a barrier to sustained virologic suppression in low- and middle-incom

289 started on treatment, which can result in a sustained virological response (effective cure).

290 ple living with hepatitis C virus (HCV) with sustained virological response (SVR) develop hepatic com

291 Sustained virological response at 12 weeks post-treatmen

292 us infection (which was treated, achieving a sustained virological response when she was 18 years old

293 generated new antiviral CD8 T cells, despite sustained virus replication in the thymus, indicating an

294 Cumulative incidence of time to first sustained vision gain of 15 or more Early Treatment Diab

295 nts to the trillions of cells in our body to sustain vital life processes.

296 The devices produce a sustained voltage of around 0.5 volts across a 7-microme

297 LMM aRR 0.85, 95% CI 0.83 - 0.87 and lack of sustained VS (N=2,499; LR aRR 0.75, 95% CI 0.68 - 0.83;

298 The incidence and timing of CHB or sustained VT within 30 days post-ASA were assessed.

299 nts in auditory and vestibular function were sustained well into adulthood.

300 ng dynamics, were switched from transient to sustained when receptor internalization was inhibited wi