ライフサイエンスコーパス: swap

1 arm domain and GF domain in each monomer are swapped).

2 ends to generate homodimers through a domain swap.

3 alent murine locus, corresponding to a locus swap.

4 main to first unfold, then refold via domain swap.

5 cery purchases and suggestions for lower SFA swaps.

6 cur in nature: domain-swapped and non-domain-swapped.

7 third images from the top were inadvertently swapped.

8 erse case study, input/output variables were swapped.

9 near-isogenic lines with the VRN-A1 alleles swapped.

10 that legends of Fig. 1 and Fig. 2 have been swapped.

11 l SAM reaction to complete the oxygen-sulfur swapping.

12 ementation, circular permutation, and domain swapping.

13 from the monomer and does not require domain-swapping.

14 rovides a prime exemplar of bona fide domain-swapping.

15 can form oligomers without undergoing domain-swapping.

16 ithin each subunit without undergoing domain swapping.

17 taneously dimerise through C-terminal strand swapping.

18 ta-strand and by traditional cystatin domain swapping.

19 gh-efficiency genetic pipeline for transgene swapping.

20 15(-)cKIT(+) myeloid DC progenitors, whereas SWAP-70 acts subsequently.

21 SWAP-70 and DEF6 regulate steady-state DC cytokine expre

22 SWAP-70 and DEF6-mediated restriction of DC differentiat

23 SWAP-70 controls Cer accumulation through the regulation

24 cells, and highlights the important role of SWAP-70 in Cer dynamics in dendritic cells.

25 nd biochemical assays to analyze the role of SWAP-70 in lipid dynamics.

26 r combined, of the related proteins DEF6 and SWAP-70 strongly enhances differentiation of murine GM-C

27 SWAP-70 was required for regulating the increase and loc

28 ested a role of switch-activated protein 70 (SWAP-70) in lipid raft formation of dendritic cells.

29 Contrasting SWAP-70, control through DEF6 does not depend on RHOA ac

30 stabilized in a native-like trimeric form by swapping a domain from BG505 Env to 4-2.J41 Env.

31 As a result of the RLC swapping, actin filament sliding velocity increased by ~

32 t, donor species and genomic location of the swap all influenced outcomes-both the nature of adaptive

33 Swapping analyses identified distinct knottin scaffold s

34 Domain-swap analysis showed that the non-Pd localization is als

35 Deletion and domain-swapping analysis identified that the C-terminal extensi

36 We show, using a domain swap and point mutations, that the leucine-rich repeat (

37 tachment to the pore occur in nature: domain-swapped and non-domain-swapped.

38 g in close structural proximity, both domain-swapped and nondomain-swapped ASIC M2 conformations need

39 t the lower part of M2 can adopt both domain-swapped and nondomain-swapped conformations.

40 this interaction might occur in both domain-swapped and nonswapped conformations.

41 SbnI forms a dimer through C-terminal domain swapping and a dimer of dimers through intermolecular di

42 mutation, L68Q, increases the rate of domain-swapping and causes a fatal amyloid disease, hereditary

43 lts reveal structural determinants of domain swapping and raise the possibility that a single ion cha

44 l molecule is used to trigger protein domain swapping and subsequent activation of biological functio

45 o discriminate domains susceptible to domain swapping and to identify structural regions with high pr

46 oped Conpair, a tool for detection of sample swaps and cross-individual contamination in whole-genome

47 tiscale method to accelerate the rate of the swaps and reach the so-called infinite-swap limit that i

48 eportation of spin eigenstates, entanglement swapping, and gate teleportation.

49 SNAC-linked precursors and present a domain swapping approach to reprogramming these enzymes for pep

50 s of constant region shuffling and subdomain swapping approaches to create improved ("i") chimeric mA

51 These swaps are typically attempted every few MD steps and acc

52 eric ion channels have either swapped or non-swapped arrangements of the S1-S4 and pore domains.

53 proximity, both domain-swapped and nondomain-swapped ASIC M2 conformations need to be considered.

54 ts voltage-sensor domain adopts a non-domain-swapped attachment to the pore and contacts the cytoplas

55 monthly personalized feedback and healthier swaps based on nutritional analysis of loyalty card data

56 7SK HP1 highlights an original mechanism of swapping bases, which could represent a possible '7SK si

57 nning residues 1-15 (1) preceding the domain-swapped Bcl-2-like domains.

58 Experiments in which conditioned medium was swapped between cultures showed that extrinsic factors s

59 eptual states emerge when the two images are swapped between the eyes multiple times per second; (iii

60 divergence (divergence regions, or DRs) were swapped between the toxins.

61 inding P-loop and adjoining beta strands are swapped between two chains in the dimer.

62 t likely occur through intermolecular domain swapping between dimer folds.

63 Domain swapping between hPg and mouse Pg emphasizes the importa

64 s that the tendency to perform tandem domain swapping between PDZ1 and PDZ2 is highly conserved, as d

65 we demonstrate coherent optomechanical state swapping between two spatially and frequency separated r

66 Reciprocal swaps between beta6 and beta8 betaI domains increase aff

67 To investigate this, we created domain swaps between the close homologs Gpa2 and Rx1, which con

68 In contrast, swapping carboxy-terminal phosphatidylinositol 4,5-bisph

69 and on a network of sovereign credit default swaps (CDS).

70 Using alphaS/betaS domain-swapped chimera constructs and single residue substituti

71 Domain swap chimeras also revealed previously unknown functiona

72 f 140 sequence modifications, including loop-swap chimeras and single-residue mutations distributed t

73 ions of dynamin isoforms in CME using domain swap chimeras.

74 human adults' over 12/14 set-size/number-of-swaps combinations, until four items were manipulated wi

75 e activation loops are in an extended domain-swapped configuration.

76 Shaker-like VGKC show domain-swapped configuration: VSD of one subunit is covalently

77 ally estimate the stability of tandem domain-swapped conformations from the structures of single doma

78 can adopt both domain-swapped and nondomain-swapped conformations.

79 general strategy to prevent TCR mispairing: swapping constant domains between the alpha and beta cha

80 Moreover, using HCMV::EBV hook domain swap constructs, computational prediction of the roles o

81 imulated 'brain transplants'-computationally swapping controllers and plants between individuals.

82 e was found to feature a trans-linked domain swap, converting an intramolecular disulfide to intermol

83 a new oligomeric arrangement, with a domain-swapped, cross-armed conformation for the protomers in t

84 Nuclear magnetic resonance (NMR) and H1 tail-swapping cryo-EM experiments revealed that the C-termina

85 Swapping cyclases between cyanobacteria and purple photo

86 hase boundaries, anti-site point defects and swap defects.

87 validate causation through reciprocal allele swaps, demonstrating the functional consequences of nonc

88 evious studies, we have established a module-swapping design principle to engineer allosteric respons

89 ks-willingness (at least 50% of the time) to swap devices or attend the clinic for a change in SNR--w

90 making a number of chimeric TFs in which we swapped different domains of Cbf1p and Tye7p and determi

91 SALDHs exist as equilibrium between a domain-swapped dimer and the dimer-of-dimers tetramer.

92 GIPC1 forms a domain-swapped dimer in an autoinhibited conformation that hind

93 h SARAF validate the formation of the domain-swapped dimer in cells and demonstrate that dimerization

94 in complex with Mn2+/Mg2+ revealed a domain-swapped dimer in which the central alpha5-alpha7 helices

95 "SARAF-fold." The structure reveals a domain-swapped dimer in which the last two beta-strands (beta9

96 HC84.26.5D assembles into a bivalent domain-swapped dimer in which the two V(L)/V(H) modules are sep

97 RapZ self-associates into a domain swapped dimer of dimers, and in vivo data support the im

98 nuous alpha-helix, as stabilized by a domain-swapped dimer.

99 d M(pro)C can exist as a monomer or a domain-swapped dimer.

100 formation toward an unproductive off-pathway swapped-dimer state.

101 gions interact to form an integrated, domain-swapped dimeric assembly.

102 that enables FoxP2 and FoxP3 to form domain-swapped dimers capable of bridging two DNA molecules in

103 romosome loci together via functional domain-swapped dimers formed through their DNA-binding domains.

104 The structures reveal that three domain-swapped dimers of the enzyme form a trilobed structure.

105 uring conditions, CysC forms inactive domain-swapped dimers.

106 docked in the substrate site of the KD in a swapped-domain dimeric arrangement.

107 The trimers in an open conformation swap domains with each other.

108 k for the rational reengineering of NRPSs by swapping domains handling different substrates to genera

109 We have discovered that the domain-swapped (DS) dimer of hCRBPII undergoes a large and robu

110 formation of a previously postulated domain-swapped (DS) FoxP1 dimer in solution and reveal the pres

111 ory effects of NAM S37a on: 1) chimeras with swapped ectodomain, 2) stepwise N-terminal truncations,

112 esultant modulating plant transpiration, the SWaP enables quantification of the component of RWU dist

113 e human-to-mouse low-affinity FcgammaR locus swap engendered hFcgammaRIIA/IIB/IIIA/IIIB expression in

114 nct substrate specificity, as illustrated by swapping enzymes from distantly related cyanobacterial a

115 The neural model explains both swap errors and response variability as results of decod

116 sion, and found a strong correlation between swap errors occurring in spatial and nonspatial report.

117 Second, responses are corrupted by "swap errors", in which a different item from the memory

118 ding failure in this task is associated with swap errors, in which observers report an item other tha

119 Domain-swap experiments and point mutations identified the Nck1

120 Domain swap experiments between pepper Bs3 and Arabidopsis (Ara

121 ed to high affinity EWS binding and sequence swap experiments between target and non-target demonstra

122 sent among the CD1b-specific TCRs, but chain swap experiments demonstrated that CD1b specificity was

123 Domain swap experiments establish that the family-specific loop

124 u proteins in a T-cell line, as well as tail swap experiments exchanging the cytoplasmic tail of HLA-

125 Protein domain-swap experiments identify a region including the STAR do

126 Previous gene knockout and promoter swap experiments showed that PpCESAs from class A (PpCES

127 our protein sequence comparisons and domain swap experiments support the hypothesis that transmembra

128 opus, which are further supported by residue-swapping experiments involving the L1 loop of CENP-A.

129 Domain-swapping experiments with LGR4 and LGR5 revealed that th

130 This is only the second example of a domain-swapped Fab dimer from among >3000 Fab crystal structure

131 Bivalent domain-swapped Fab dimers engineered on the basis of HC84.26.5D

132 t in conversion from a domain-swapped to non-swapped fold.

133 to receive evidence-based dietetic advice to swap foods for similar, but healthier, choices and incre

134 We have tested these residue swaps for their ability to trigger recruitment of beta-a

135 The swapped form of Nck-SH3.1 is unable to bind CD3e, possib

136 that switching between monomeric and domain-swapped forms may regulate DNA selectivity of TEAD prote

137 This leads us to extend the theory of domain-swapping from the level of monomeric subunits and multim

138 We also exploit the domain swapping function of VidaL to effect simultaneous modifi

139 f high-performance polymers with unique bond-swapping functionality and unusual glass-forming behavio

140 We show that highly reliable special swap gate is achievable by different detuning.

141 By swapping genomic sequences, we found that the genomic lo

142 Propagated domain-swapping has been proposed as the mechanism by which Cys

143 Swapping has important implications for the mechanism of

144 bundles connected by a long, curved pair of swapped helical domains.

145 ted mutation in helix 15, suggesting that a "swapped" helix pair, 15 and 16, is part of a structural

146 t between a tryptophan in the M(pro)C domain-swapping hinge and an arginine elsewhere forms early dur

147 crystallography, we have discovered a domain-swap homodimerization mode in CYP51 from a human pathoge

148 mone receptor 1 (MCHR1), and splicing factor SWAP homolog (SFRS8)] was associated with the degree of

149 e domain of free RI crystallizes in a domain-swapped homotetramer, which likely works as a sink for R

150 fibrils, contradicting the propagated domain-swapping hypothesis.

151 The Mxra8 ectodomain contains two strand-swapped Ig-like domains oriented in a unique disulfide-l

152 and a target protein that undergoes a domain swap in response to binding of the triggering ligand.

153 We report an evolutionary swap in the formation of RNLs, which emerged from the fu

154 to the active site cysteine induces a domain swap in Ube2T that leads to cyclic trimerization organiz

155 OR in the whole cell lysate (WCL) blots were swapped in Fig.

156 mental tests of quantum science.Entanglement swapping in high dimensions requires large numbers of en

157 bilizing AU-rich elements into the 3'-UTR or swapping in naturally occurring 3'-UTRs conferring diffe

158 Domain swapping in the alpha-helical C-terminal domain of M(pro

159 We show that swapping in the telomerase essential N-terminal (TEN) an

160 All chains/swaps incorporating compatible pairs included ABO/HLA in

161 /AC413/rAmy variants with C-terminal residue swaps indicated that the C-terminal sCT/rAmy residue ide

162 Here we introduce induced domain swapping (INDOS) as a mechanism for regulating protein f

163 patient with a FOXP3 mutation in the domain swap interface of the protein.

164 uncharacterized disulfide-bridge and domain-swapped interfaces from crystal formation in Bti to diss

165 found that chimeras containing rat E570-V686 swapped into chicken receptors displayed capsaicin sensi

166 al activation by using chimeric ligands with swapped intracellular domains (ICDs), demonstrated that

167 lar understanding of the mechanism of domain swapping, investigations into the biological relevance o

168 he intrinsic PRC2 dimer is formed via domain swapping involving RBBP4 and the unique C2 domain of SUZ

169 The SWaP is therefore a promising device offering new insigh

170 n agreement with the view that tandem domain swapping is a potential source of transient misfolding,

171 interaction, hotspots grafting with CDR loop swapping is an attractive route to the rational design o

172 e SARAF luminal switch shows that the domain swapping is essential to function and indicates that the

173 Domain swapping is the process by which identical proteins exch

174 ermolecular chain reaction similar to domain swapping, is the most probable mechanism of aggregate pr

175 Sec7d) on GBF1 functionality was assessed by swapping it with the Sec7d from ARF nucleotide-binding s

176 l coupling and gating polarity in non-domain-swapped K(v) channels on the basis of the cryo-electron

177 V)7.1, and likely applies to numerous domain-swapped K(V) channels.

178 f the swaps and reach the so-called infinite-swap limit that is known to optimize sampling efficiency

179 lding, whereas the alpha-helices are free to swap locally in the native basin.

180 In contrast, swapping loop 12 had negligible effects on motor velocit

181 To overcome this, entanglement swapping may be used to generate remote quantum correlat

182 d SARS-CoV-2, mutations that modulate domain swapping may provide insights into the role of octameric

183 SWAP-MEAT (The Study With Appetizing Plantfood-Meat Eati

184 a beta4A-beta5A beta-hairpin runaway domain swap mechanism for antithrombin polymerization.

185 We determine the optimal entanglement swapping method that maximizes the entanglement rate of

186 Fkh1- and Fkh2-domain-swap-minus (dsm) mutations are functional as transcripti

187 Simulations of these loop-swapped motors using experimentally derived motor parame

188 Key charge swap mutagenesis experiments provided evidence for pairw

189 )/Galpha(13) chimeras and individual residue swap mutations into these sensors defined that selectivi

190 rent implementation of REMD in which (i) the swaps obey a continuous-time Markov jump process impleme

191 Domain swaps observed previously in other SH3 domains indicate

192 The domain swapping occurs at the hinge region between the beta3 an

193 anti-symmetric states, and thus entanglement swapping occurs for several thousand pairs of spatial li

194 Described here is that the simple swap of 1-methyl to 1-phenyl on 1-(benzoyloxymethyl)CPEs

195 " mechanism that enables a phospho-triggered swap of protein partners by Raf Kinase Inhibitory Protei

196 In corollary, the reciprocal swap of the AAV1RX footprint onto AAVrh.10 (AAVRX1) atte

197 Central to dimer formation is a domain swap of the conserved C-terminal helix of Ku80.

198 explanations have been put forward, such as swapping of adjacent domains, but there is a lack of com

199 Our results show that domain swapping of FoxP1 occurs at micromolar protein concentra

200 V expressing a fluorescent protein tolerated swapping of GP with counterparts from heterologous filov

201 Here, we investigate the mechanism of domain swapping of M(pro)C using coarse-grained structure-based

202 Here we demonstrate entanglement swapping of multiple orbital angular momentum states of

203 Here the authors demonstrate entanglement swapping of multiple spatial modes of light simultaneous

204 Here, Weaver et al. demonstrate coherent swapping of optomechanical states between two separate r

205 iscussed the cause and consequence of domain swapping of OsWRKY45-DBD, and based on our work and that

206 Swapping of plastomes between the three different genomi

207 Here we show that systematic swapping of pre-existing variation in a subfamily of pla

208 We observe frequent swapping of strong and weak promoters in the context of

209 Cross-dimer domain-swapping of the C-terminal region is a determinant of al

210 -acid difference at the CC' loop of CD300LF; swapping of these amino acids between C57BL/6J and I/LnJ

211 ts have quite different characteristics: The swaps of beta-strands proceed via global unfolding, wher

212 within SRCR domain 5, or replacement (domain swap) of SRCR domain 5 with a synthesized exon encoding

213 molecular dynamics simulations, with domain swap oligomerisation being thermodynamically favoured.

214 lly disordered regions can facilitate domain swapping oligomerization and other tightly regulated ass

215 These non-swapped oligomers are identical in secondary structure t

216 The non-swapped oligomers likely represent a dead-end offshoot o

217 127-nt fragment encompassing improved PSs is swapped onto the RNA otherwise lacking CP recognition mo

218 efficient implementation of the exponential-SWAP operation(6) and present its experimental realizati

219 ces a coherent superposition of identity and SWAP operations between arbitrary states of two harmonic

220 dot array, we generate a series of coherent SWAP operations to transfer both single-spin and entangl

221 Tetrameric ion channels have either swapped or non-swapped arrangements of the S1-S4 and por

222 Directional processing is maintained despite swapping or duplicating the two tRNAs consistent with in

223 if DNA samples from a cohort are mislabeled, swapped, or contaminated or if they include unintended i

224 The inactivating mutations become 'swapped out' in the dimer, increasing nuclease and ribos

225 PP2A heterotrimer composed of the A/B charge-swap pair and the endogenous catalytic subunit.

226 f varying set sizes of occluded objects that swapped places a number of times.

227 and interactive, visual detection of sample swaps, poor sequencing quality, and other indicators of

228 lly favored, in contrast to classical domain-swapping proteins.

229 involves pioneering techniques to coherently swap qubits encoded within the motional states of a trap

230 g that H3K27me3 dominantly represses histone swapping rate even in the presence of the more permissiv

231 To assess the content of such HL-chain swapped reaction products with high sensitivity, we deve

232 CysC mutant, V57N, stabilized against domain-swapping, readily forms fibrils, contradicting the propa

233 n a manner dependent on the conserved domain-swapping region, strongly suggestive of homodimer format

234 The gene exchanges swapped regions between 0.5 and 139 Kb in length (183 Kb

235 Site-directed mutagenesis that swapped residue 153 between UGT89A2 from Col-0 and C24 r

236 Such a loop2 swap restored activation of the N-truncation Orai1 mutan

237 AcCYP51 dimerized head-to-head via N-termini swapping, resulting in formation of a nonplanar protein-

238 uch a sulfonyl group dance (functional group swap) results from a cascade of S(N)Ar reactions, which

239 Cross-kingdom domain swaps reveal functional equivalence of animal and plant

240 Swapping segments also transferred chemokine-binding act

241 We demonstrate that hot-swapping sensors between experiments allows for convenie

242 We define the term of entanglement swapping set that models the status of quantum memory of

243 glement rates for the different entanglement swapping sets and noise levels.

244 glement swapping sets, complete entanglement swapping sets and perfect entanglement swapping sets.

245 ntum repeaters at the different entanglement swapping sets as function of the noise of the local memo

246 ity properties for non-complete entanglement swapping sets, complete entanglement swapping sets and p

247 ement swapping sets and perfect entanglement swapping sets.

248 Our SWaP setup can measure the RWU and redistribution of san

249 crystal structure of DEP1 features a domain swap, similar to that observed previously in the Dvl2 DE

250 We explore whether swapping some instructional language with questions in p

251 ormation of fragment-complemented and domain-swapped species.

252 We present the TAndem DOmain Swap Stability predictor (TADOSS), a method to computati

253 Here we carefully analyzed the isotope label swapping strategy for phosphoproteomics, using data cons

254 roduced against chimeric VLPs that presented swapped structural domains, shell and protruding (P), fr

255 Here we show how swapping structural elements between two bacteriophytoch

256 V)11.1), have revealed an original nondomain-swapped structure, suggesting that the mechanism of volt

257 is for antagonist selectivity and mutational swap studies confirmed this hypothesis.

258 ate from occupying the same orbital-tends to swap the spin states of neighbouring electrons.

259 e this, we generated genomic inversions that swap the Xist/Tsix transcriptional unit and place their

260 s mEos2-A69T and Dendra2-T69A, we completely swapped the blinking behaviors of mEos2 and Dendra2, two

261 We have swapped the individual regions between different OST pro

262 Here, we demonstrate that by swapping the 5' and 3' terminal packaging signals of the

263 cage introduces a new piece to the system by swapping the closed form with the open form in the solid

264 n and a quadruple mutant (QM), engineered by swapping the identity of four residues important for spe

265 th our models, our in vivo results show that swapping the KASH domains of ANC-1 and UNC-83, or shorte

266 Swapping the substituents in positions 2 and 4 of the pr

267 a tertiary structure could be retained when swapping the two backbones in a protein sequence.

268 is based on provoking intramolecular "domain swap." The results show that the alpha- and beta-element

269 itical amino acid exchanges that broaden and swap their lipid specificities.

270 ues will reduce G3 discrimination by RF2, we swapped these residues between E. coli RF1 and RF2 by si

271 Swapping this improved region into the wild-type STNV1 s

272 Swapping this residue between resistant and sensitive vi

273 Several viral proteins domain swap to increase their structural complexity or function

274 be used to determine species identity, were swapped to generate a Saccharomyces synXII strain that w

275 TRPV6 can result in conversion from a domain-swapped to non-swapped fold.

276 rocess impedes to link the functional domain swapping to human-associated diseases.

277 lates the folding route, and promotes domain swapping to the native structure.

278 es of deletions, point mutations, and domain swaps to identify a 12-residue region (residues Gln-62-L

279 ing and pore domains to produce a non-domain-swapped transmembrane architecture, which appears to be

280 We observed that the probability of swapping two items strongly correlated with the items' s

281 In three-dimensional domain swapping, two protein monomers exchange a part of their

282 eveals the sensory N-terminus to be a domain-swapped variant of the cNMP/CRP family, which in the cAM

283 y subunit families, we engineered A/B charge-swap variants that could bind to one another, but not to

284 at KvAP from Aeropyrum pernix has non-domain-swapped voltage sensors as well as other unusual feature

285 died Kv1-7, Nav and Cav channels have domain-swapped voltage sensors, much less is known about non-do

286 annels, the HCN channel does not have domain-swapped voltage sensors.

287 ace, analogous to the S4-S5 linker of domain-swapped voltage-gated channels.

288 sensors, much less is known about non-domain-swapped voltage-gated ion channels.

289 meric BACs, in which two TERT promoters were swapped, were also generated.

290 , until four items were manipulated with 3-4 swaps, where performance decreased toward that of 6- to

291 e (AcCYP51)] formed a dimer via an N-termini swap, whereas drug-bound AcCYP51 was monomeric.

292 meric pseudovirions with inter-genotype loop swaps which demonstrated that the L1 domains recognised

293 e present a sensor, the soil water profiler (SWaP), which can determine local soil water content (the

294 he same time, HSV and PRV homologs cannot be swapped, which suggests that in addition to a conserved

295 sm whereby Lewis acid undergoes a counterion swap with the complex which favors isomerization as well

296 ls that all incoming density matrices can be swapped with a target density matrix.

297 p2, whereas the F-BAR domain of Cdc15 can be swapped with several different F-BAR domains, including

298 positively charged loop 12 of kinesin-3 was swapped with that of kinesin-1, the landing rates revers

299 quantum repeater implies stable entanglement swapping with the boundness of stored density matrices i

300 A chimeric UHRF1 (finger swap) with diminished E3 ligase activity toward nucleoso