ライフサイエンスコーパス: sweat

1 profile variation of S. miltiorrhiza after "Sweating".

2 rhiza showed a significant difference after "Sweating".

3 hould be investigated metabolome-wide after "Sweating".

4 in epidermally-retrievable biofluids (e.g., sweat).

5 ormance in solutions intended to approximate sweat.

6 rticle (AgNP) dissolution rates in simulated sweat.

7 uch as interstitial fluid, saliva, tears and sweat.

8 collection of discrete microliter volumes of sweat.

9 ulation for continuous access to analytes in sweat.

10 e determination of chloride concentration in sweat.

11 ensing platform for monitoring biomarkers in sweat.

12 wearable biochemical diagnostics from human sweat.

13 egrated sensing for on-body testing of human sweat.

14 sol (8.16 to 141.7 ng/mL) in perspired human sweat.

15 es over prolonged and continuous exposure to sweat.

16 r materials for the detection of chloride in sweat.

17 em have never been reported to be present in sweat.

18 tiometric analysis of pH, Na(+), and K(+) in sweat.

19 valuated their performance in the artificial sweat.

20 s COX-dependent cutaneous vasodilatation and sweating.

21 y delayed the mean body temperature onset of sweating (+1.24 +/- 0.18 vs. +1.60 +/- 0.18 degrees C, P

22 mptoms (cough, fever, weight loss, and night sweats; 1 point each), and >14-day symptom duration.

23 expected physiological levels of glucose in sweat (10-200 muM), and the calibration parameters are d

24 mance is evaluated with different volumes of sweat (20, 50, and 100 uL), bending radii (10, 15, 20 mm

25 "Sweating", a processing method of Traditional Chinese Me

26 tract dysfunction, orthostatic hypotension, sweating abnormalities, or erectile dysfunction.

27 d microfluidics with passive valves serve as sweat-activated "stopwatches" that record temporal infor

28 ave provided evidence of viscerally-mediated sweating alterations in humans during exercise brought a

29 phoresis interface, integrated in a wearable sweat analysis platform.

30 are embedded in a flexible sampling cell for sweat analysis.

31 onsiderable promise for noninvasive wearable sweat analysis.

32 The observed correlation between sweat and blood considering low-molecular weight metabol

33 followed by increased glucose levels in both sweat and blood.

34 lot study examined cortisol concentration in sweat and saliva samples collected from 48 college-aged

35 ause they function at high pH (pH > 10), and sweat and tears are neutral (pH = 7).

36 wever, metal oxide sensors do not operate in sweat and tears because they function at high pH (pH > 1

37 Continuous glucose monitoring from sweat and tears can improve the quality of life of diabe

38 developmental delay, seizures, and a lack of sweat and tears.

39 The results suggest that sweat and urine analysis can be a promising method to ro

40 The effect of vitamin C intake on the sweat and urine profile is explored by monitoring concen

41 disposable biosensors capable of monitoring sweat and vaginal pH.

42 lysis indicated distinct differences between sweated and non-sweated samples.

43 n-flush changes in cutaneous vasodilatation, sweating and cerebral blood flow.

44 Effects of blanching, sweating and drying on these characteristics were assess

45 The "wet process", including blanching, sweating and drying, had the largest impact on the compo

46 nd left flank abdominal pain, accompanied by sweating and fatigue.

47 heating layer that serves to both stimulate sweating and prevent saturation of the sensing area, red

48 thermoregulatory responses, both autonomic (sweating) and behavioral (peeling off a layer of clothin

49 id, a behaviorally active component of human sweat, and they lack odor-evoked responses to acidic vol

50 hat primarily originate from saliva, plantar sweat, and urine sources.

51 relevant levels in neutral fluids mimicking sweat, and wireless communication with a personal comput

52 sturbances, drowsiness or tiredness, nausea, sweating, and being restless or overactive) did not diff

53 e elevations in cutaneous vasodilatation and sweating, and reduced brain blood flow.

54 Conjunctival hyperemia, lip swelling, cold sweats, and nausea presented later.

55 is, fever, chronic cough, weight loss, night sweats, and poor appetite).

56 HO) 4-symptom screening (fever, cough, night sweats, and weight loss), a rapid test detecting mycobac

57 ficant differences between apocrine-dominant sweat (AP), saliva before exercise (SBE), and saliva aft

58 ajor thermoregulatory defences in humans are sweating, arteriovenous shunt vasoconstriction, and shiv

59 inch valves and suction pumps for purging of sweat as a reset mechanism to coincide with hydration ev

60 an be circumvented by placing water or human sweat as molecular attractants on the top (external) fil

61 The developed SC uses sweat as the electrolyte and poly(3,4-ethylenedioxythiop

62 ET-1 does not modulate methacholine-induced sweating at any of the administered concentrations.

63 Previously reported sweat-based and other non-invasive biosensors either can

64 ene, sufficient to form a wearable patch for sweat-based diabetes monitoring and feedback therapy.

65 metabolome as health indicators, discovering sweat-based disease biomarkers, and metabolomic mapping

66 A sweat-based flexible supercapacitor (SC) for self-powere

67 first demonstration of the suitability of a sweat-based SC for self-powered cloth-based sensors to m

68 with a higher CT(max) (53.1 degrees C) than sweat bees (50.3 degrees C) and honeybees (49.1 degrees

69 zation, for three bee species: silky striped sweat bees (Agapostemon sericeus), western honeybees (Ap

70 Moreover, bumblebees and sweat bees were closer to their CT(max) in more urbanize

71 Sweat bees were the least sensitive to desiccation, with

72 hysical (temperature, biopotential) sensors, sweat biochemical (pH, uric acid, glucose) sensors, ther

73 or non-invasive and in situ multi-sensing of sweat biomarkers including glucose, lactate, pH, chlorid

74 future evaluation of temporal changes of the sweat biomarkers.

75 ur developed SWSP sensor for the analysis of sweat biomarkers.

76 nitoring of total sweat loss, sweat rate and sweat biomarkers.

77 olites, proteins, etc.) stability in complex sweat buffer with varying pH levels and composition over

78 Successful detection of lactate in human sweat by means of the poly(3-APBA) based sensor has been

79 pted for the determination of metabolites in sweat by the naked eye in the form of a 3 x 15 mm colour

80 Human sweat can be noninvasively collected and used as a media

81 orm is designed such that continuous flow of sweat can pass through an array of flexible microneedle

82 ility to quantitatively capture time-dynamic sweat chemistry in scenarios compatible with field use.

83 Comprehensive analysis of sweat chemistry provides noninvasive health monitoring c

84 improvements from baseline were observed in sweat chloride (-24.8 mmol/L; 95% CI, -29.1 to -20.5; P

85 y secondary outcomes were absolute change in sweat chloride and Cystic Fibrosis Questionnaire-Revised

86 p<0.0001) and the key secondary outcomes of sweat chloride concentration (LSM treatment difference -

87 Shifts in sweat chloride concentration and lung function reported

88 Subjects with Type 2 profiles had higher sweat chloride concentration and weight loss, higher max

89 decreasing the load from 200 W to 100 W, the sweat chloride concentration decreased from 27.7 +/- 10.

90 In this work, we recorded real-time sweat chloride concentration for 12 healthy subjects in

91 ng the exercise load from 100 W to 200 W the sweat chloride concentration increased from 12.0 +/- 5.9

92 Sweat chloride concentration provides an in vivo assessm

93 4 points) that was 20.2 points higher, and a sweat chloride concentration that was 41.8 mmol per lite

94 ent to chemically-induced sweating where the sweat chloride concentration was almost independent of s

95 caftor and absolute changes from baseline in sweat chloride concentration, growth parameters, and mar

96 es and correlate with key clinical features (sweat chloride concentration, pancreatic exocrine status

97 For the key secondary endpoint of sweat chloride concentration, the least squares mean dif

98 tcomes were absolute change from baseline in sweat chloride concentrations and bodyweight, body-mass

99 Mean sweat chloride concentrations decreased by 31.7 mmol/L,

100 enlargement in both cohorts and had elevated sweat chloride concentrations in the derivation cohort (

101 The measured sweat chloride concentrations were in the range from 2.9

102 Sweat chloride is of interest as a biomarker for cystic

103 oride and a diffusion-limited response time; sweat chloride levels corresponded to measurable changes

104 Elevated sweat chloride levels, failure to thrive (FTT), and lung

105 test precision and accuracy can be improved, sweat chloride measurement could be a valuable biomarker

106 o assess the feasibility of using a wearable sweat chloride sensor for real-time monitoring of indivi

107 F specific clones that correlate highly with sweat chloride test, BMI, and FEV1% predicted values.

108 Sweat chloride testing was suggestive of CFTR dysfunctio

109 were found to be the primary determinant of sweat chloride variability (56.1% of variation) with con

110 e degree to which CFTR mutations account for sweat chloride variation.

111 For an individual with CF, variation in sweat chloride was primarily caused by variation over ti

112 While the changes in sweat chloride were statistically significant, there was

113 2 profiles at 125 W, showing an increase in sweat chloride with exercise intensity.

114 The half-time associated with the change in sweat chloride, defined as the time at which the concent

115 Improvements in lung clearance index, sweat chloride, nutritional status, and health-related q

116 Sweat collected during sport practice was first analyzed

117 sease biomarkers, and metabolomic mapping of sweat collected from different areas of skin with and wi

118 ges associated with standard technologies in sweat collection and analysis.

119 Thus, the combination of noninvasive sweat collection and CIL LC-MS is a robust analytical to

120 e report a simple and inexpensive method for sweat collection over a defined period (e.g., 24 h) base

121 omprises a microfluidic cell designed with a sweat collection zone coupled to a fluidic channel in wh

122 t allows for precise measurements of dynamic sweat composition fluctuations using in situ or ex situ

123 ors enable the monitoring of an individual's sweat composition in real time.

124 r, recording of time-dependent variations in sweat composition requires bulky electronic systems and

125 entification of personal dynamic patterns in sweat composition while practicing sport.

126 bled real-time monitoring of sweat profiles (sweat concentration versus time) and could enable monito

127 horseradish peroxidase, to correlate ethanol sweat concentrations to the production of a color that i

128 g sweat must be selective in the presence of sweat constituents.

129 that, the designed sampling cell avoids any sweat contamination and evaporation issues while supplyi

130 or Stim1 and Stim2 (Stim1/2K14Cre) failed to sweat despite normal sweat gland development.

131 ith and without CF, demonstrating convenient sweat diagnostics with reliable detection of cystic fibr

132 The rate of sweat droplet formation was significantly slower and the

133 t formation was significantly slower and the sweat droplet size larger and more variable in db/db mic

134 nally, db/db mice formed significantly fewer sweat droplets compared to controls as early as 6 weeks

135 n factor, Foxc1, is obligate for appreciable sweat duct activity in mice.

136 In summary, Foxc1 regulates sweat duct luminal cell differentiation, and mutant mice

137 fine structures inside the mouse pinna, and sweat ducts and Meissner's corpuscle in the human finger

138 emristor types, one that originates from the sweat ducts and one that is based on thermal changes of

139 Morphologic analysis revealed that sweat ducts were blocked by hyperkeratotic or parakerato

140 les, sebaceous glands, taste buds, nails and sweat ducts.

141 n according to local dynamic fluctuations in sweat during on-body tests.

142 With our platform, we detected the elevated sweat electrolyte content of cystic fibrosis patients co

143 r chronic disease management to non-invasive sweat electrolyte sensors for dehydration monitoring in

144 ntoxication levels of an individual based on sweat ethanol levels.

145 ducted using a metabolite expressed in human sweat, Ethyl Glucuronide.

146 th pH-meter readings and IC after collecting sweat (every 10-12.5 min) during sport practice.

147 evaporation issues while supplying a passive sweat flow encompassing specifically the individual's pe

148 d vein blood, confirming diagnostic value of sweat for diabetes monitoring.

149 easuring chloride levels in artificial human sweat for potential cystic fibrosis diagnostic use.

150 erface that can extract sufficient amount of sweat for robust sensing, without electrode corrosion an

151 Clinical validation was performed with sweat from individuals with and without CF, demonstratin

152 nnels consisted of cotton threads to harvest sweat from the skin surface and to transport it to the p

153 Intraepidermal (IENFD), sweat gland (SGNFD), and pilomotor nerve fiber densities

154 tim1/2K14Cre) failed to sweat despite normal sweat gland development.

155 oma are distinctive skin adnexal tumors with sweat gland differentiation and potential for malignant

156 aquaporin 5 (AQP5), and other regulators of sweat gland function was normal in the absence of SOCE.

157 and defects in dental enamel production and sweat gland function.

158 e intraepidermal nerve fiber (IENF) density, sweat gland innervation index of structural protein gene

159 c skin response of the foot was impaired and sweat gland innervation was reduced.

160 be exploited to advance our knowledge of the sweat gland physiology and the secretion process.

161 n, possibly due to reduced blood flow to the sweat gland resulting in a lack of tissue perfusion.

162 Genes that determine sweat gland structure and function are largely unidentif

163 ate from a variety of sources, including the sweat gland, which produces lactate from the glucose rec

164 When Foxc1 was specifically ablated in skin, sweat glands appeared mature, but the mice were severely

165 Sweat glands are critical for thermoregulation.

166 nalyses and functional studies, we show that sweat glands are specified by mesenchymal-derived bone m

167 The single tubular structure of sweat glands has a lower secretory portion and an upper

168 ed SVV ORF63 protein at the following sites: sweat glands in skin; type II cells in lung alveoli, mac

169 We observed that autonomic innervation of sweat glands in the footpads was significantly reduced i

170 lves delivery of stimulating agonists to the sweat glands with the aid of an electrical current.

171 -green birefringence within dermal collagen, sweat glands, and arrector pili that engulfed axons.

172 driven by the secretion of moisture from the sweat glands, since increased hydration in stratum corne

173 nt inflammatory skin disease of the apocrine sweat glands.

174 olaterally in the reabsorptive duct of human sweat glands.

175 mpaired chloride secretion by primary murine sweat glands.

176 s including the airways, colon, pancreas and sweat glands.

177 ommodate pressure built-up, when interfacing sweat glands.

178 The dynamics of sweat glucose concentration, recorded by means of the pr

179 s and preliminary investigation of the blood/sweat glucose correlation.

180 signs of health such as the glucose level in sweat has attracted increasing attention recently, due t

181 ease in blood and in noninvasively collected sweat has been observed ( r = 0.75).

182 We conclude that "Sweating'' has significant effect on metabolites content

183 She had no fevers, chills, night sweats, hemoptysis, wheezing, chest pain, palpitations,

184 he perceived impact of hot flushes and night sweats (HF/NS) and overall levels of menopausal symptoms

185 ivity towards chemosensory stress signals in sweat; however, it is still unknown whether endogenous n

186 of increased heart rate and blood pressure, sweating, hyperthermia, and motor posturing, often in re

187 tes through continuous analysis of undiluted sweat immediately after its excretion using a flow-throu

188 nterleukin-6 (IL-6) and Cortisol, from human sweat in RTILs.

189 The inherent inaccessibility of sweat in sedentary individuals in large volume (>/=10 mi

190 that, although prostacyclin does not mediate sweating in young and older males, it does modulate cuta

191 eported in 52%, weight loss in 57% and night sweats in 48% of patients.

192 % of patients, weight loss in 57%, and night sweats in 48%.

193 t an epidermal patch for glucose analysis in sweat incorporating for the first time pH and temperatur

194 Short-term adverse events-acne, night sweats, increased weight, and altered mood and libido-ar

195 flective of sensor performance in artificial sweat, indicating that further characterization is neces

196 ody's sympathetic nervous system measured as sweat-induced changes in the skin's electrical conductan

197 n body and efficiently sample fluids such as sweat, interstitial fluids, tear and saliva for the elec

198 llergenic cochineal for the first time; cold sweat, intraoral discomfort, respiratory distress, and u

199 Human sweat is an excellent biofluid candidate for metabolomic

200 Chloride in sweat is an important diagnostic marker for cystic fibro

201 The noninvasive continuous analysis of human sweat is of great significance for improved healthcare d

202 nsors has been focused on systems to measure sweat l-lactate and other metabolites, where the employm

203 ostructural optics for reversible readout of sweat loss, and effervescent pumps and chemesthetic agen

204 anomalous physiological events, such as high sweat loss, requires user engagement to observe colorime

205 or continuous, real-time monitoring of total sweat loss, sweat rate and sweat biomarkers.

206 ed delivery of sensory warnings of excessive sweat loss.

207 hetically mediated pulsatile changes in skin sweat measured as EDA resemble an integrate-and-fire pro

208 fast response time, adequate selectivity for sweat measurements, and excellent reversibility.

209 olome, offering a possibility of mapping the sweat metabolic differences according to skin locations.

210 etection and relative quantification of 3140 sweat metabolites with 84 metabolites identified and 271

211 s, simultaneous and selective measurement of sweat metabolites, electrolytes and temperature was achi

212 plications including daily monitoring of the sweat metabolome as health indicators, discovering sweat

213 , demonstrating the possibility of using the sweat metabolome to reveal biological variations among d

214 a location-dependence characteristic of the sweat metabolome, offering a possibility of mapping the

215 Significant differences in male and female sweat metabolomes could be detected, demonstrating the p

216 nd CIL LC-MS is a robust analytical tool for sweat metabolomics with potential applications including

217 Sensors intended for measuring sweat must be selective in the presence of sweat constit

218 tness occurring secondary to the build-up of sweat on the skin provokes thermal discomfort, the precu

219 xication based on the presence of ethanol in sweat on the skin surface.

220 hoeic athletes, chronic OCP use impaired the sweating onset threshold and thermosensitivity (both P <

221 orrhoea OR 2.65, 95% CI 1.26 to 5.86; facial sweating OR 2.53, 95% CI 1.33 to 4.93).

222 ion and fur growth, short-term shivering and sweating or panting, and movement between warm and cold

223 but denied experiencing fever, chills, night sweats, or gastrointestinal, musculoskeletal, or neurolo

224 He did not report fever, night sweats, or hemoptysis.

225 The developed Smart Wearable Sweat Patch (SWSP) sensor comprises highly fluorescent s

226 h) based on the use of a nonocclusive style sweat patch adhered to a skin.

227 , user-friendly, ultra-low-cost (~0.03 $ per sweat patch), portable, selective, rapid, and non-invasi

228 ble solution for the real-time monitoring of sweat pH and the accurate at-home diagnosis of bacterial

229 e attachment to skin, where they can monitor sweat pH, or to the surface of paper-based sample contai

230 ntaneous heart rates, respiratory rates, and sweat pH, uric acid, and glucose, as well as deliver pro

231 n noninvasively retrievable biofluids (e.g., sweat), play a critical role, because they can be deploy

232 Like the smart human sweating pores, the flaps can close automatically after

233 cant symptoms were weight loss, fever, night sweats, productive cough and haemoptysis.

234 sensors have enabled real-time monitoring of sweat profiles (sweat concentration versus time) and cou

235 Finally, we show that sweat profiles along with other physiological parameters

236 While all five subjects showed Type 1 sweat profiles at 75 W, four of the subjects had Type 2

237 he influence of level of effort, we recorded sweat profiles for five subjects at 75 W, 100 W, and 125

238 uring exercise, we recorded and analyzed the sweat profiles of 50 healthy subjects while spinning at

239 The sweat profiles showed two distinct sweat responses: Type

240 The components of sweat provide an array of potential biomarkers for healt

241 emia and no symptoms of early satiety, night sweats, pruritus, or erythromelalgia.

242 tes the changes in cutaneous vasodilatation, sweat rate and cerebral blood flow during a hot flush.

243 set threshold and thermosensitivity of local sweat rate and forearm blood flow relative to mean body

244 s, real-time monitoring of total sweat loss, sweat rate and sweat biomarkers.

245 Local sweat rate and/or forearm blood flow differed as a funct

246 Following training, mean hot flush sweat rate decreased by 0.04 mg cm(2) min(-1) at the che

247 nt, there was no correlation with changes in sweat rate or other physiological parameters, which we a

248 No effect on sweat rate was observed in either group (all concentrati

249 Cutaneous vascular conductance (CVC) and sweat rate were assessed in three protocols: in Protocol

250 Sweat rate, cutaneous vasodilatation, blood pressure, he

251 ride concentration was almost independent of sweat rate.

252 ecrease in reabsorption efficiency at higher sweat rates.

253 rmacokinetic correlation and significance of sweat readings.

254 e and glycopyrrolate increased and decreased sweating, respectively, in 6 month-old controls, db/db m

255 and also that chronic OCP use attenuates the sweating response, whereas behavioural thermoregulation

256 The sweat profiles showed two distinct sweat responses: Type 1 (single plateau) and Type 2 (mul

257 henotype was strikingly similar to the human sweat retention disorder miliaria.

258 A longitudinal study of sweat's and urine's vitamin C correlation with blood is

259 self-powered cloth-based sensors to monitor sweat salinity is presented.

260 Human subject studies of time-stamped sweat samples by in situ colorimetric methods and ex sit

261 ntify the amount of ethanol within authentic sweat samples collected from individuals who had consume

262 7 unique metabolites were detected across 54 sweat samples collected from six individuals with an ave

263 LC-MS for mapping the metabolome profiles of sweat samples collected from skins of the left forearm,

264 Detection of cortisol levels in human sweat samples has also been investigated and the results

265 Three 24-h sweat samples were collected at three different days fro

266 monitoring of tryptophan (Trp) in blood and sweat samples, with a linear range of 0.02-0.8 mm.

267 porting for the presence of EtG in the human sweat samples.

268 distinct differences between sweated and non-sweated samples.

269 irely laser-engraved sensor for simultaneous sweat sampling, chemical sensing and vital-sign monitori

270 d to routinely monitor nutrition through the sweat sensor and that this sensor can facilitate applica

271 report on a wearable potentiometric chloride sweat sensor.

272 Wearable sweat sensors have enabled real-time monitoring of sweat

273 Wearable sweat sensors have the potential to provide continuous m

274 nt/materials, in the fabrication of wearable sweat sensors, have limited their feasibility as a perso

275 in interstitial fluid, and device-integrated sweat stimulation for continuous access to analytes in s

276 to fearful) while they were exposed to both sweat stimuli and a non-social control odor following in

277 of biochemical markers in biofluids, such as sweat, tears, saliva and interstitial fluid.

278 nuous and non-invasive molecular analysis in sweat, tears, saliva, interstitial fluid, blood, wound e

279 ic reflex screens (77%) and thermoregulatory sweat test (67%) confirmed sudomotor dysfunction.

280 small fibers; 29 patients (60%) had abnormal sweat test results, 21 (42%) had abnormal pain threshold

281 s autonomic (heart rate, blood pressure, and sweat testing) and subjective testing of pain.

282 l elevations in cutaneous vasodilatation and sweating that are accompanied by reduced brain blood flo

283 With real human sweat the observed energy and power densities are 0.25 W

284 With artificial sweat, the energy and power densities of the SC are 1.36

285 idity increases, as might occur during human sweating thus permitting air flow and reducing both the

286 dehydration via skin sensations initiated by sweat-triggered ejection of menthol and capsaicin.

287 amin C concentration in biofluids, including sweat, urine, and blood is developed.

288 sed analgesic and antipyretic) in saliva and sweat, using a surface-modified boron-doped diamond sens

289 Limit of detection of IL-6 in human sweat was 0.2 pg/mL for 0-24 hours and 2 pg/mL for 24-48

290 etection of IL-6 over 0.2-200 pg/mL in human sweat was demonstrated for a period of 10 hours post-ant

291 rial detection of IL-6 and Cortisol in human sweat was established with minimal cross-talk for 0-48 h

292 Axillary sweat was obtained from 30 healthy male donors undergoin

293 The response to exercise-induced sweating was significantly different to chemically-induc

294 patient was asymptomatic and denied fevers, sweats, weight loss, shortness of breath or dyspnea on e

295 Levels of uric acid in sweat were higher in patients with gout than in healthy

296 ignificantly different to chemically-induced sweating where the sweat chloride concentration was almo

297 Sweat, which contains rich chemical information, is an a

298 c amperometric detection of lactate in human sweat with boronate-functionalized polyaniline has been

299 Analysis of human sweat with poly(3-APBA) based sensor is possible due to

300 This interface can be programmed to induce sweat with various secretion profiles for real-time anal