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1 thymidine kinase and the human sodium-iodide symporter.
2 is based on the structure of a uracil-proton symporter.
3 arK2 is proposed to be a Type I H(+)/nitrate symporter.
4 ortation of nitrate involved an H(+)/nitrate symporter.
5 We show that UCP1 is an LCFA anion/H(+) symporter.
6 oordinates of LacY and the oligopeptide/H(+) symporter.
7 pergillus nidulans purine-cytosine/H(+) FcyB symporter.
8 iver the cognate ligand to the transmembrane symporter.
9 g that PLUTO functions as a proton-substrate symporter.
10 as well as the X-ray structure of a related symporter.
11 ulaxalba, PtaSUT4, is a tonoplast (Group IV) symporter.
12 h a second protein, PitA, a cation-phosphate symporter.
13 port in mammalian cells suggest Slc11a1 is a symporter.
14 ing hormone in stimulating the sodium-iodide symporter.
15 e, the channel functions as a proton/protein symporter.
16 s that express the endogenous or transfected symporter.
17 ing that it is likely to be a nitrate/proton symporter.
18 inase, HPr, enzyme I, and the galactose:H(+) symporter.
19 ssion of thyroglobulin and the sodium/iodide symporter.
20 and unbinding in the Na(+)-coupled substrate symporters.
21 d kinetic mechanism for the H(+)-coupled MFS symporters.
22 insights into substrate selectivity in AgcS symporters.
23 ovided from the environment via myo-inositol symporters.
24 ast, and bacteria as divalent metal ion/H(+) symporters.
25 that LmaNT3 and LmaNT4 are nucleobase/proton symporters.
26 ers, suggesting a distinctive fold for Na(+) symporters.
27 into the function of neurotransmitter:sodium symporters.
28 r phloem loading of sucrose via sucrose-H(+) symporters.
29 he enhanced accumulation of Suc via Suc/H(+) symporters.
30 e coupled to protons via the monocarboxylate symporters.
32 so indicated that LjSUT4 is a proton-coupled symporter: (14)C-sucrose uptake into LjSUT4-expressing o
33 volutionarily broad family nucleobase-cation symporter-2 (NCS2) encompasses transporters that are con
35 e and H(+) ions and whether the lactate/H(+) symporter activity is sufficient to give rise to the obs
38 ansporter ProP of Escherichia coli, a proton symporter and a member of the major facilitator superfam
39 dosimetry in targeting of the sodium-iodine symporter and describe the clinical application of (124)
40 demonstrate that it functions as a K(+)/H(+) symporter and report a 3.7 angstrom cryo-EM structure of
42 sialic acid transporters: one sodium solute symporter and two ATP binding cassette (ABC) transporter
44 residue conservation similar to that of the symporters and channels, and consistent with the crystal
45 ngs to the family of neurotransmitter:sodium symporters and controls dopamine (DA) homeostasis by med
46 nt action on sodium-coupled neurotransmitter symporters and elucidates critical elements of eukaryoti
47 for the mechanism of neurotransmitter sodium symporters and their modulation by therapeutic and illic
48 hyroglobulin, thyroperoxidase, sodium iodide symporter, and deiodinase type 2, and deiodinase type 2
49 ogen exchanger 3, aquaporin 7, sodium iodide symporter, and hydrogen potassium adenosine triphosphata
52 mologue of mammalian neurotransmitter sodium symporters, and show that the tricyclic antidepressant (
53 homolog of mammalian neurotransmitter sodium symporters; and 2), rhodopsin and the beta1- and beta2-a
54 ligand-binding protein, and a transmembrane symporter apparatus comprising the M and Q components (M
57 pallidum, tp0957 (the SBP), and tp0958 (the symporter), are in an operon with an uncharacterized thi
58 levels of BvSUT1, a sugar beet leaf sucrose symporter, are negatively regulated specifically by sucr
59 and binding sites in neurotransmitter/sodium symporters arose from conflicting data in crystal struct
60 transporters able to function as Na(+)-K(+) symporters, at least when expressed in yeast (Saccharomy
62 g a T-DNA disruption of the bile acid sodium symporter BASS6 show decreased photosynthesis and slower
63 the corresponding structures of the related symporter BetP reveals alternating orientations of the b
66 sporters, the ABC transporter CbcXWV and two symporters, BetT1 and BetT3, in P. aeruginosa growth on
67 downstream of the neurotransmitter reuptake symporter bloated tubules (blot), whose Drosophila ortho
68 was required for expression of sodium-iodide symporter but was not required for thyroglobulin express
69 tic understanding of neurotransmitter sodium symporters but have left fundamental questions unanswere
70 roteins are hypothesized to be the Na(+) /Pi symporters catalysing Pi uptake in chlorophytes, whereas
71 olarization similar to the non-GLR, putative symporter component and in most cases evoked little or n
73 ructure of Escherichia coli D-galactonate/H+ symporter D-galactonate transporter (DgoT) in 2 states:
75 tein is a member of the divalent anion/Na(+) symporter (DASS) family and shares significant sequence
76 d into the cell by the divalent anion sodium symporter (DASS) family of plasma membrane transporters,
77 cS, is a member of the divalent anion sodium symporter (DASS) family that also includes the mammalian
78 embrane proteins of the divalent anion/Na(+) symporter (DASS) family translocate dicarboxylate, trica
79 porter is a member of the divalent-anion/Na+ symporter (DASS) family, a group that includes the mamma
80 -mediated reduction of PttSUT3 (for Suc/H(+) symporter) during secondary cell wall formation in devel
82 dium-dependent lysophosphatidylcholine (LPC) symporter expressed at the blood-brain barrier that tran
85 We show that, whereas thyroidal Na(+)/I(-) symporter expression is thyroid-stimulating hormone (TSH
86 litator superfamily (MFS), the sodium solute symporter family (SSF; only in the animal kingdom), and
88 rs (NATs) within the sodium-neurotransmitter symporter family and have characterized a member of the
89 the only member of the oligosaccharide:H(+) symporter family in the Major Facilitator Superfamily th
90 epresentative of the neurotransmitter:sodium symporter family of secondary transporters(3), by imagin
91 permease belongs to the oligosaccharide:H(+) symporter family of the Major Facilitator Superfamily an
92 caK and is conserved in the aromatic acid/H+ symporter family of the major facilitator superfamily of
93 arding glycoside-pentoside-hexuronide:cation symporter family transporters and other Na(+)-coupled pe
94 to the glycoside-pentoside-hexuronide:cation symporter family, a part of the major facilitator superf
98 e eukaryotic SLC6 family of Na(+) -dependent symporters for amino acids, neurotransmitters, osmolytes
102 endent, whereas many neurotransmitter:sodium symporters from higher organisms depend on Cl(-) ions.
103 pared with all other neurotransmitter:sodium:symporters, GAT-1 and other members of the GABA transpor
104 MV engineered to express the sodium iodide symporter gene (MV-NIS) facilitates localization of vira
106 n transcription of a phloem-specific sucrose symporter gene in a regulatory system that may play a pi
109 The Staphylococcus epidermidis glucose/H(+) symporter (GlcP(Se)) is a membrane transporter highly sp
110 We consider the trimeric Na(+)-aspartate symporter Glt(Ph), a homolog of an important class of ne
113 rium Pyrococcus horikoshii, sodium/aspartate symporter GltPh, suggested the molecular basis of the tr
115 late transporter 4 (MCT4) is an H(+)-coupled symporter highly expressed in metastatic tumors and at i
116 folate transporter (PCFT) is a folate-proton symporter highly expressed in solid tumors that can sele
118 We incorporated the human sodium iodide symporter (hNIS) and the human somatostatin receptor 2 (
119 n, including the loss of human sodium iodide symporter (hNIS) expression, radioactive iodide (RAI) th
120 nic antigen (CEA) or the human sodium iodide symporter (hNIS) for oncolytic potential in hepatocellul
121 mulation mediated by the human sodium iodide symporter (hNIS) gene in conjunction with various imagin
122 cardiac gene expression after sodium iodide symporter (hNIS) gene transfer in cardiac transplantatio
123 Anion transport by the human sodium-iodide symporter (hNIS) is an established target for molecular
124 ted vector coding for the human sodiumiodide symporter (hNIS) led to hNIS expression by these cells a
125 rine transporter (hNET), human sodium-iodide symporter (hNIS), a human deoxycytidine kinase double mu
126 rus, GLV-1h153, carrying human sodium iodide symporter (hNIS), in combination with radioiodine in an
128 tal structure of the neurotransmitter/sodium symporter homolog LeuT revealed an occluded binding pock
132 the Staphylococcus epidermidis glucose/H(+) symporter in an inward-facing conformation at 3.2-A reso
133 e molecular dynamics simulations of the UraA symporter in phospholipid bilayers consisting of: 1) 1-p
134 own expression domain of the AtSUC2 Suc-H(+) symporter in the epidermis of the cell division zone of
135 that a specialized form of the sodium/iodide symporter in the mammary gland mediates active iodide tr
136 ine isotopes for targeting the sodium-iodine symporter in thyroid cancer and nonthyroidal neoplasms a
137 resses hNIS, increases the expression of the symporter in TNBC cells, and serves both as a gene marke
140 of PM proteins like Pma1p and nutrient H(+)-symporters inducing their ubiquitination and internaliza
143 trate transport in sodium-coupled amino acid symporters involves a large-scale conformational change
145 The Staphylococcus epidermidis glucose/H(+) symporter is homologous to human glucose transporters, i
147 Na(+) and sugar transport by cotransporters (symporters) is thought to occur as a series of ordered l
148 genes homologous to H+[or Na+]/myo-inositol symporters (ITRs), not previously studied in plants.
149 y firefly luciferase and human sodium-iodide symporter labeling of cardiosphere-derived cells were in
150 Few side chains in the galactoside/H(+) symporter LacY (lactose permease of Escherichia coli) ar
152 ndicate that the mammary gland sodium/iodide symporter may be an essential breast cancer marker and t
155 r was determined to be homologous to that of symporters mediating the transport of the same or relate
156 ia coli HS4006 containing the melibiose-H(+) symporter (MelY) from Enterobacter cloacae that had enha
158 eishmania donovani has a myo-inositol/proton symporter (MIT) that is a member of a large sugar transp
159 F1 increased thyroglobulin and sodium/iodide symporter mRNA levels, cell migration, and proliferation
160 s, using a mutant lacking the nitrate/proton symporter NasA from the assimilatory nitrate reductase p
161 ncodes a phloem-localized sucrose (Suc)/H(+) symporter necessary for efficient Suc transport from sou
162 rine interferon beta (IFNbeta)-sodium iodide symporter (NIS) (VSV-mIFNbeta-NIS) oncolytic virus has s
168 the current study, we used the sodium iodide symporter (NIS) as a theranostic gene to investigate whe
171 ls stably expressing the human sodium iodide symporter (NIS) fused to a red fluorescent protein, ther
176 , thiocyanate, and nitrate are sodium/iodide symporter (NIS) inhibitors that block iodide uptake into
186 ctor PBF repress expression of sodium iodide symporter (NIS) messenger RNA (mRNA), and inhibit iodide
188 Established cell lines expressing the Na/I symporter (NIS) were used to quantify the effect of ICM
189 biosynthesis, is mediated by the Na(+)/I(-) symporter (NIS) with an electrogenic 2Na(+):1I(-) stoich
190 uptake, which is mediated by the Na(+)/I(-) symporter (NIS), in vivo (dSUV/dt: vehicle, 0.028 +/- 0.
191 ntranslated region of PAX8 and sodium/iodide symporter (NIS), leading to impaired protein translation
192 ne kidney cells expressing the sodium iodide symporter (NIS), pendrin, or NIS and pendrin using a bic
193 C1 decreases expression of the sodium/iodide symporter (NIS), the molecule that mediates radioiodide
195 pothyroidism: mice lacking the sodium/iodide symporter (NIS), the plasma membrane protein that mediat
204 le in tumor progression of the sodium/iodide symporter (NIS; aka SLC5A5), which is upregulated and mi
205 ial homologue of the neurotransmitter:sodium symporter (NSS) family and, being the only NSS member to
206 member (Tyt1) of the neurotransmitter:sodium symporter (NSS) family has been cloned from Fusobacteriu
207 ryotic member of the neurotransmitter/sodium symporter (NSS) family is a major advance toward underst
208 (DAT) belongs to the neurotransmitter:sodium symporter (NSS) family of membrane proteins that are res
226 gue of the mammalian neurotransmitter/sodium symporters (NSSs), we studied the properties of proteomi
229 transporter family, which includes Na(+)/Pi symporters of fungal and animal origin and H(+)/Pi sympo
230 roposed to function as either nitrate/proton symporters or nitrate/nitrite antiporters based on seque
231 either "apoplastically" (by using H+/sucrose symporters) or "symplastically" (through plasmodesmata).
232 ermease; PA2042 for a putative sodium:serine symporter; PA3934, which belongs to the family of small
233 ese viruses use the related sodium-phosphate symporters Pit1 and Pit2, respectively, as receptors in
235 ne protein (specifically H(+)-osmoprotectant symporter ProP) to the Escherichia coli cell poles.
237 time that the involvement of a sodium solute symporter protein as a Bt functional receptor has been d
239 subunit and the transmembrane subunit of the symporter proteins are postulated to have four correspon
240 rily conserved among neurotransmitter:sodium symporter proteins as a binding pocket for small molecul
242 , the function of TM6' in the sodium/proline symporter PutP, a member of the solute/sodium symporter
243 ium that expresses a neurotransmitter sodium symporter-related protein with sequence and structural h
245 the first exon of SLC13A1, a sodium/sulfate symporter responsible for regulating serum levels of ino
250 plying that SSSs and neurotransmitter-sodium symporters share common mechanistic elements in substrat
251 f a homologous archaeal sodium and aspartate symporter showed that a dedicated transport domain carri
252 on decreased expression of the sodium iodide symporter SLC5A5 (NIS), diminished membrane targeting of
254 lactose transporter (vSGLT), a solute-sodium symporter (SSS) from Vibrio parahaemolyticus, shares a c
255 l structure of a member of the solute sodium symporters (SSS), the Vibrio parahaemolyticus sodium/gal
257 fied mutants of the plasma membrane Suc/H(+) symporter SUC1, indicating that the accumulation of Suc
259 exported transporters and the proton/sucrose symporter Sucrose Transporter1 To accumulate plant sugar
260 els to the KtrAB, Trk, Trk1,2, and HKT1 K(+) symporter superfamily of both prokaryotes and eukaryotes
261 ma membrane, proton-coupled Group II sucrose symporters (SUT) mediate apoplastic phloem loading and s
262 N-I), E-cadherin (TcCad1), and sodium solute symporter (TcSSS) have been identified by ligand blot as
263 the suc2 mutation disables a sucrose/proton symporter that facilitates sucrose loading from leaves i
264 ansporter (PCFT; SLC46A1) is a proton-folate symporter that is abundantly expressed in solid tumors a
265 accumulation of HAK5, a putative (H(+))/K(+) symporter that mediates a high-affinity uptake during K(
266 ons of the CTNS gene, encoding cystinosin, a symporter that mediates cystine efflux from lysosomes.
267 ANSPORTER 1 (PHT1) proteins are the H(+) /Pi symporters that carry out Pi uptake in angiosperms.
268 eurotransmitter transporters are ion-coupled symporters that drive the uptake of neurotransmitters fr
269 as a homolog of Pho4, a family of phosphate symporters that includes the bacterial PitA proteins.
272 essenger), which binds to the galactose:H(+) symporter (the target), resulting in uncoupling of sugar
273 LC5A8 gene, is 70% similar to the Na(+)/I(-) symporter, the protein that mediates active I(-) uptake
274 also inhibited the activities of two proton symporters, the osmosensing transporter ProP and the lac
275 cus on two well-characterized sodium-coupled symporters: the bacterial amino acid transporter LeuT, w
277 ic target genes thyroglobulin, sodium iodide symporter, thyroperoxidase, and thyroid-stimulating horm
279 46 [HPr(Ser-P)], binds to the galactose:H(+) symporter to uncouple sugar transport from proton sympor
280 phy imaging of the hNIS (human sodium/iodide symporter) to noninvasively quantify adeno-associated vi
281 (LeuT), a model for neurotransmitter sodium symporters, to show that various amino acid substrates i
282 ll lines showed an increase in sodium-iodine symporter transcription when treated with a MEK or BRAF(
286 e deduced amino acid sequence of each insect symporter was determined to be homologous to that of sym
287 t encoding a putative plasma membrane proton symporter was isolated, because it was coordinately regu
288 egulation of the mammary gland sodium/iodide symporter, we demonstrate by scintigraphy that mammary a
289 xpression in frog oocytes shows Slc11a2 is a symporter, whereas Slc11a1 is an antiporter fluxing diva
290 GAT-1 belongs to the neurotransmitter:sodium:symporters which are crucial for synaptic transmission.
291 1 is a member of the neurotransmitter:sodium:symporters, which are crucial for synaptic transmission.
292 t is a member of the neurotransmitter:sodium:symporters, which are crucial for synaptic transmission.
293 and a member of the neurotransmitter:sodium:symporters, which are crucial for synaptic transmission.
294 8 is a member of the family of sodium solute symporters, which are now added as a class of candidate
295 ort that NarK1 functions as a nitrate/proton symporter while NarK2 is a nitrate/nitrite antiporter.
296 folate transporter (PCFT) is a folate-proton symporter with an acidic pH optimum, approximating the m
299 that recombinant SITs are Na(+)/silicic acid symporters with a 1:1 protein: substrate stoichiometry a
300 radioiodine in tissues that express the Na/I symporter without affecting the ability to image the tum