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1 euron pathophysiological mechanisms underlie tactile abnormalities in different ASD mouse models and
4 hannels to control neuronal excitability and tactile acuity through tonic inhibition of thalamic neur
5 ative to their length was predicted by their tactile acuity, supporting the influence of the cortical
6 ) between the felt and vicariously perceived tactile affectivity led to higher subjective embodiment
7 detection thresholds (p < 0.01), impaired C-tactile afferents (p < 0.05), and reduced amplitudes (p
10 hy, quantitative sensory testing including C-tactile afferents, and pain-related evoked potentials.
12 terestingly, peripheral nerve injury induces tactile allodynia and upregulates Ca(V)3.2 channels and
13 entration able to activate the HCAR2-reduced tactile allodynia in female WT mice, but not in the HCAR
14 males and females display a severe sustained tactile allodynia which is reduced by gabapentin but not
17 n after SNL contributes nerve injury-induced tactile allodynia.SIGNIFICANCE STATEMENT Neuropathic pai
18 SnF(2) or hydroxyapatite were beneficial for tactile and air stimulus with high to moderate certainty
19 ept brain-to-spine interface (BTSI), whereby tactile and artificial sensory information are decoded f
23 sponses, here, we measured BOLD responses to tactile and auditory stimuli for both JMD patients and c
26 derstanding the dissociable contributions of tactile and kinesthetic information to perception and ac
29 kground 5-HT3R mediated facilitation of both tactile and nociceptive spinal activity in the first thr
30 it modules that cooperate to convey thermal, tactile and noxious cutaneous signals from the spinal co
32 tral to a wide range of functions, including tactile and pain perception, hearing, proprioception, an
33 m ABSTRACT: Numerous studies have documented tactile and proprioceptive deficits in children with cer
34 developed as a novel platform for delivering tactile and proprioceptive feedback in clinical applicat
36 lassify, and discriminate various intermixed tactile and thermal stimuli using a machine-learning app
37 n nonhuman primates presented with auditory, tactile, and audio-tactile stimuli as they are progressi
39 se components differentiated between visual, tactile, and auditory stimuli suggesting the presence of
42 sian modeling with fMRI, we show that during tactile associative learning, prior expectations modulat
47 We first describe the multisensory (audio-tactile) characteristics of S1 and vPM neurons (mean and
50 uation occurs because the brain predicts the tactile consequences of our self-generated movements.
51 ng who received either high (HC) or low (LC) tactile contact from their parents have differences in t
52 simultaneously deliver visual, auditory and tactile content, using acoustophoresis as the single ope
54 posterior and anterior insula lesions reduce tactile, contralateral and ipsilateral pleasantness sens
57 recognition occurs via visual, chemical, or tactile cues that dictate cooperative versus competitive
58 oral predictability of tactile targets using tactile cues, which preceded the target by either consta
60 glove sensor array, we record a large-scale tactile dataset with 135,000 frames, each covering the f
61 tudy shows that animal choices during active tactile decision making can be predicted from mechanosen
63 lation and in vivo calcium imaging to assess tactile defensiveness and barrel cortex activity in youn
64 cal sensory circuits is a potential cause of tactile defensiveness in autism.SIGNIFICANCE STATEMENT W
68 o attend to one hand in order to detect rare tactile deviant stimuli at this hand while ignoring tact
69 deviant stimuli at this hand while ignoring tactile deviants at the other hand and tactile standard
70 llations, replicating previous findings, and tactile DFI to occipital beta oscillations, a rhythm typ
71 lts show that V5/hMT+ plays a causal role in tactile direction processing, and strengthen the case fo
72 Overall, these findings indicate that active tactile discrimination by rats is characterized by much
74 perceptual performance of animals performing tactile discrimination tasks through LC-norepinephrine o
75 ving rodents can make simultaneous bilateral tactile discrimination without whisking.SIGNIFICANCE STA
77 made forced-choice judgments of which of two tactile distances felt bigger, one oriented with the pro
79 tterns, suggesting a somatotopically precise tactile encoding capability of the mechanosensory dorsal
81 aracterize the effect of the prior belief of tactile events on connections mediating the outcome of p
84 of natural textures-which span the range of tactile experience and engage all the known mechanisms o
85 Motion is an essential component of everyday tactile experience: most manual interactions involve rel
92 le embedded sensors to provide comprehensive tactile feedback of a human hand when touching or holdin
95 sFES) of the lower-limbs, proprioceptive and tactile feedback, balance control through overground wal
96 ped a model to simulate the responses of all tactile fibers innervating the glabrous skin of the hand
98 d vision, we discuss the first evidence of a tactile "fovea" in birds and how this led to detailed st
99 rding microsaccades while people performed a tactile, frequency discrimination task enabled us to tes
100 e for investigating both normal and abnormal tactile function in healthy and clinical populations.
103 Using a low-cost (about US$10) scalable tactile glove sensor array, we record a large-scale tact
104 d the relationships between touch threshold, tactile gnosis, and mechanoreceptor and sensory fiber fu
106 ptors (NMDARs) in primary afferents leads to tactile hypersensitivity across skin types, and loss of
108 tantly, they provide novel evidence that the tactile-induced DFI is instead mediated by the speed of
109 oscillatory correlates of the auditory- and tactile-induced double flash illusion (DFI), a phenomeno
110 ory-to-visual areas leading to the same (but tactile-induced) DFI share similar properties with the a
111 ic devices are needed to efficiently process tactile information in a parallel and low power manner.
113 ntly limits our understanding of the role of tactile information in the human grasp itself-for exampl
115 to functional changes in these major hubs of tactile information processing, whisker stimulation duri
117 datasets with which to probe the use of the tactile information that humans rely on when grasping ob
118 The automatic remapping between skin-based tactile information to a location in external space has
119 manipulating objects, we use kinesthetic and tactile information to form an internal representation o
120 ic dorsal column (PSDC) pathway transmitting tactile information to the brain are poorly characterize
121 ubcortical pathway allows fast re-routing of tactile information to the occipital cortex, but this ha
123 sed on asymmetry, (2) even in the absence of tactile input, whisker positioning and asymmetry neverth
124 eceptors and we rely on integrating cold and tactile inputs from A-type skin nerve fibres to sense we
125 The integration of visual, auditory, and tactile inputs in the amygdala may serve social communic
126 of the network in a way that converts analog tactile 'inputs' into digital colorimetric 'outputs'.
129 improve owner's well-being, (e.g. human-dog tactile interaction increases owner's self-esteem), and
132 ic feedback system was designed to allow for tactile, kinesthetic, and vibrotactile feedback, with th
134 precision of prediction during probabilistic tactile learning.SIGNIFICANCE STATEMENT In a probabilist
135 aps in somatosensory cortex, suggesting that tactile localisation involves coding of abstract feature
136 w research demonstrates systematic errors of tactile localisation, involving confusions of body parts
137 riments demonstrating that the perception of tactile localization on a static body part is strongly a
139 n in the human grasp itself-for example, how tactile maps are used to identify objects and infer thei
143 timing of successive stimulations [2, 4, 5], tactile motion mechanisms [6], or processes that "remap"
144 Much of the research on the neural basis of tactile motion perception has focused on how direction i
145 es have reported activations associated with tactile motion perception in visual motion area V5/hMT+,
147 ce directions and strain profiles in various tactile motions (shear, pinch, spread, torsion, and so o
150 asp and manipulate an object, populations of tactile nerve fibers become activated and convey informa
151 Other types of bodily experiences, such as tactile or vestibular sensations, were not affected by t
153 g peripheral mechanosensory neurons to treat tactile over-reactivity and select ASD-related behaviors
154 s directly on mechanosensory neurons reduced tactile over-reactivity in six distinct ASD models.
155 stimate their weight and explore the typical tactile patterns that emerge while grasping objects.
156 r freely behaving rats can discriminate fine tactile patterns while running, in particular when stimu
158 ensory perturbations in visual, auditory and tactile perception are core problems in fragile X syndro
162 udy, we investigated the effect of providing tactile perception on motor coordination during routine
163 h touch signals to enable spatially accurate tactile perception, but other functions of phase coding
165 in designing suitable sensors and restoring tactile perceptions, pain perception dynamics and its de
166 ial representations can account for atypical tactile percepts in some neurological patients and amput
167 le afferents contribute to the perception of tactile pleasure, but the brain areas involved in their
168 etic stimulation (TMS) while moving a single tactile point across the fingertip, and used signal dete
170 rames encoded by oscillatory activity during tactile processing were probed by adopting either an unc
171 y plays a similar role in spatial coding for tactile processing, that is, after the stimulus has been
174 abnormalities in sensory functions, such as tactile, proprioceptive and nociceptive processing, have
175 life of chocolate and affects its visual and tactile quality, all of which are serious concerns for c
177 lementation of closed-loop VNS paired with a tactile rehabilitation regimen could improve recovery of
180 op vagus nerve stimulation (VNS) paired with tactile rehabilitation to enhance synaptic plasticity an
181 usly evaluate the ability of VNS paired with tactile rehabilitation to improve recovery in an animal
184 n but challenge the role of external-spatial tactile representations when attributing touch to a limb
188 studied for decades in the context of direct tactile sensation, but recent work has indicated that ra
190 MS) of the somatosensory cortex evokes vivid tactile sensations and can be used to convey sensory fee
195 tackle the grand challenges in pressure- and tactile-sensing applications, in particular, with recent
196 r the past decade, a brand-new pressure- and tactile-sensing modality, known as iontronic sensing has
197 he High ED group, physiological arousal, and tactile sensitivity (d') were increased when self-focuse
199 hether they differ from shoes in maintaining tactile sensitivity during walking, especially at initia
200 egnancy yielded adult offspring with altered tactile sensitivity in two aversive somatosensory behavi
201 phenotypes spanning morphology, locomotion, tactile sensitivity, and habituation learning in 135 str
202 viding protection and comfort at the cost of tactile sensitivity, cushioned footwear also lowers rate
207 rinting approach is employed to fabricate 3D tactile sensors under ambient conditions conformally ont
208 how that, in mice, the movement of whiskers (tactile sensors used to extract information about textur
211 he sensitivity and pressure-sensing range of tactile sensors, the intrinsic viscoelasticity of soft p
216 tterns presented on the tongue using electro-tactile sensory substitution devices (SSDs) have been su
218 n-noise performance in CI users using: (1) a tactile signal derived using an algorithm that could be
219 iate for a real-world application, and (3) a tactile signal that could readily be produced by a compa
220 rtantly, the inability to record and analyse tactile signals currently limits our understanding of th
224 alpha-band activity is directly involved in tactile-spatial transformation and suggest instead that
228 irds and how this led to detailed studies of tactile specializations in waterfowl and sensorimotor sy
234 and electrophysiological signals elicited by tactile stimulation co-localized to the ipsilateral dors
235 so exhibit natural variation in the level of tactile stimulation delivered by the parents to the offs
236 mice were more sensitive to relatively weak tactile stimulation in a vibrissa motion detection task.
237 n studies by near-nerve technique, including tactile stimulation of mechanoreceptors, were followed f
238 in multi-talker noise with and without vibro-tactile stimulation of the wrist in CI users, before and
239 echanisms modifiable by effects of postnatal tactile stimulation on glucocorticoid receptor gene expr
240 show using magnetoencephalography (MEG) that tactile stimulation produces occipital cortex activation
241 uring attentional orienting in expectance of tactile stimulation reflected external spatial coding in
245 r) system in the context of direct touch and tactile stimulation, but recent work has shown that rats
246 g global activation to visual, olfactory and tactile stimulation, particularly in the brainstem/cereb
247 urons in primary somatosensory cortex during tactile stimulation, we found that stimulus onset and of
251 not they spike repetitively during sustained tactile stimulation; the former are subclassified as Typ
252 hrony within 600 ms between the movement and tactile stimulations was necessary for the effect (exper
253 s have used artificially long delays between tactile stimuli and behavioral responses to aid relating
255 ivity and defensive behaviors in response to tactile stimuli are common symptoms in autism spectrum d
257 presented with auditory, tactile, and audio-tactile stimuli as they are progressively anesthetized w
258 s and stiffness, for the ability to perceive tactile stimuli at frequencies experienced during walkin
260 d to reflect the automatic transformation of tactile stimuli from a skin-based, somatotopic reference
262 sets of similar mildly aversive auditory and tactile stimuli in 42 high-functioning children and adol
263 nes.SIGNIFICANCE STATEMENT Overreactivity to tactile stimuli is a common symptom in autism spectrum d
264 ection Task (SSDT), which involved detecting tactile stimuli on the cheek in the presence or absence
267 ce learned to discriminate 'go' from 'no-go' tactile stimuli(10,11) and adapt their behaviour upon re
277 that newborns' saccadic reaction times to a tactile stimulus simultaneous to sounds with different i
285 Moreover, microsaccades occurring around the tactile target presentation are associated with reduced
286 nd that microsaccades are inhibited prior to tactile targets and more so for constant than variable i
287 e manipulated the temporal predictability of tactile targets using tactile cues, which preceded the t
288 s, revealing a tight crossmodal link between tactile temporal expectation and oculomotor action.
289 dorsal premotor cortex during comparison of tactile temporal patterns can be understood in terms of
290 d most prevalent sensory experience includes tactile, thermal, and olfactory stimulation delivered to
291 st human lesion study on the perception of C-tactile touch in right hemisphere stroke patients (N = 5
292 defensive and emotional responses, and light tactile touch may induce unpleasant itch sensations (mec
298 eshold tasks involving subjective reports of tactile, visual, or auditory stimuli during the same mag
300 d a task in which mice distinguished between tactile "word" sequences constructed from distinct vibra