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1 tasiRNAs were generated in the transgenic seedlings, and
5 e we tested several artificial microRNA- and tasiRNA-based methods for multiplexed gene silencing in
7 L4 showed functional redundancy in siRNA and tasiRNA production and in the establishment and maintena
8 , the phasing patterns of known tasiRNAs and tasiRNA-like loci from across the Arabidopsis genome wer
15 ion and specific sequence complementarity in tasiRNA formation, providing new insights into tasiRNA b
16 siRNA formation, providing new insights into tasiRNA biogenesis as well as a strategy for improving t
18 al approaches, the phasing patterns of known tasiRNAs and tasiRNA-like loci from across the Arabidops
20 re we present SoMART, a web server for miRNA/tasiRNA analysis resources and tools, which is designed
27 g is solely required for phase definition of tasiRNAs, and they strongly support recruitment of RDR6
30 e stop codons caused a dramatic reduction of tasiRNAs and over-accumulation of 3' cleavage products,
31 phased inflorescence RNAs resembles that of tasiRNAs and raise the possibility that these novel smal
33 ' for identifying miRNA precursors (MIRs) or tasiRNA precursor (TASs) of input sRNAs, and 'sRNA mappe
34 , we identified 79 conserved miRNA:target or tasiRNA:target interactions, of which eight were further
35 who are interested in identifying miRNAs or tasiRNAs that potentially regulate genes of interest.
36 itial targeting by one or multiple miRNAs or tasiRNAs, the most conspicuous example of which was an e
39 RNA pathway, that of miR173-TAS1/2, produces tasiRNAs regulating a set of pentatricopeptide repeat (P
40 3 dcl4 triple mutant showed markedly reduced tasiRNA and siRNA production and indicated that DCL1, in
42 t unique trans-acting small interfering RNA (tasiRNA) biogenesis profiles and target specificities.
43 cialized trans-acting short interfering RNA (tasiRNA) precursors can be designed to produce several s
46 tion of trans-acting small interfering RNAs (tasiRNAs) dependent upon a second ancient microRNA, miR3
47 As) and trans-acting small interfering RNAs (tasiRNAs) play important roles in a variety of biologica
48 As) and trans-acting small interfering RNAs (tasiRNAs) regulate mRNA stability and translation, and s
50 fferent plant families, have evolved similar tasiRNA pathways to initiate phased small interfering RN
52 mary transcripts into the transacting siRNA (tasiRNA) biogenesis pathway involving RNA-DEPENDENT RNA
53 but less conserved TAS3 trans-acting siRNAs (tasiRNAs) in addition to tasiR-ARFs, with expanded poten
55 ins several families of trans-acting siRNAs (tasiRNAs) that form in 21-nucleotide phased arrays throu
56 atin-associated siRNAs, trans-acting siRNAs (tasiRNAs), and natural antisense transcript (NAT)-associ
57 ring RNAs (siRNAs), and trans-acting siRNAs (tasiRNAs), control gene expression and epigenetic regula
58 MicroRNAs (miRNAs), trans-acting siRNAs (tasiRNAs), heterochromatic siRNAs (hc-siRNAs) population
59 r biogenesis of phased, trans-acting siRNAs (tasiRNAs), whose cleaved precursor fragments are convert
62 ocus was modified to produce synthetic (syn) tasiRNA to target an endogenous transcript encoding PHYT
65 ility to generate amiRNA and multiplexed syn-tasiRNA constructs for efficient gene silencing in Arabi
67 Current methods to generate amiRNA or syn-tasiRNA constructs are not well adapted for cost-effecti
70 ineered to express authentic amiRNAs and syn-tasiRNAs from minimal precursors in Nicotiana benthamian
72 evels of accurately processed amiRNAs or syn-tasiRNAs, and (3) had reduced levels of the correspondin
73 tic trans-acting small interfering RNAs (syn-tasiRNAs) are used for small RNA-based, specific gene si
74 tic trans-acting small interfering RNAs (syn-tasiRNAs) for efficient and specific targeted gene silen
76 with ARGONAUTE 1 (AGO1) during TAS1 and TAS2 tasiRNA formation, and we provide data indicating that t
82 ing and experimentation, we demonstrate that tasiRNA regulation confers sensitivity and robustness on
88 6 function causes increased miR390-triggered tasiRNA accumulation and decreased accumulation of tasiR
89 n of gametophores, elevated miR390-triggered tasiRNA accumulation, and reduced level of tasiRNA targe
93 dopsis thaliana TAS1 and TAS2 families yield tasiRNA that form through miR173-guided initiation-cleav