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1 ating taurine) to >1.6 mM (after conjugating taurine).
2 the endogenous intracellular L-glutamate and taurine.
3 of radiolabeled selenium-75 homocholic acid taurine.
4 solution of naphthalene dialdehyde (NDA) and taurine.
5 glycine, pyruvate, and the Ca(2+) regulator taurine.
6 ogic evidence of rapid reepithelization with taurine.
7 ulates the agonist properties of glycine and taurine.
8 ue to GAT2, and this uptake was inhibited by taurine.
9 2-transfected HEK293 cells transported [(3)H]taurine.
10 pha-CEHC glycine glucuronide, and alpha-CEHC taurine.
11 the oxo group and the C1 proton of substrate taurine.
12 a result of the efflux of the intracellular taurine.
13 d neurotransmitters glutamate, aspartate and taurine.
14 radiolabelled d-[(14) C]aspartate and [(3) H]taurine.
15 (TM3) side chain, important for transport of taurine.
16 w breeds that shared ancestry with the Asian taurines.
21 he density in the mature neurons, except for taurine; 4) under hypoxia, all these amino acids decreas
22 tion, 27 metabolites (tryptophan, serotonin, taurine, 8 acylcarnitines, 13 glycerophospholipids, and
23 h sexes were a decrease in concentrations of taurine (a major organic osmolyte), carnitine (involved
26 ated Schiff base adduct of retinaldehyde and taurine (A1-taurine, A1T) that forms reversibly by nonen
27 base adduct of retinaldehyde and taurine (A1-taurine, A1T) that forms reversibly by nonenzymatic reac
28 ree possible substrates of NAT biosynthesis (taurine, acetyl-CoA, and acetate), the level of taurine
29 n sum, this study provides new evidence that taurine activates a serotonin system, apparently via 5-H
31 attack by N(2)O(3); (iii) the nitrosation of taurine affords ethanesultone (ES), which displays alkyl
32 ng three pairwise comparisons among European taurine, African taurine, and indicine groups, we furthe
33 urinary clearance of beta-PEA, agmatine and taurine after oral intake by healthy individuals demonst
38 the treatment of alcohol withdrawal, and by taurine, an ingredient of certain 'energy drinks' often
40 imals (n=425) show an unfluctuating zebu and taurine ancestry of 0.84+/-0.009 s.d. and 0.16+/-0.009 s
41 tions of tissues and cellular fractions with taurine and acetate indicated that the kidney has the hi
42 e expressed in human embryonic kidney cells, taurine and AL34662, a non-specific 5-HT(2) receptor act
43 he contents of free hydrophobic amino acids, taurine and carnosine/anserine were elevated after hydro
44 of a large amount of the ester conjugate of taurine and D-peptide allows intracellular esterase to t
46 icity and oxidative stress including reduced taurine and glutathione; (3) inhibition of several devel
47 metabolism, aminoacyl-tRNA biosynthesis and taurine and hypotaurine metabolism were enriched after P
48 al genomic ancestry analyses, we reconstruct taurine and indicine ancestry genome-wide and along chro
49 nsity SNP genotyping data to investigate the taurine and indicine ancestry in southern European cattl
54 neurochemical markers of neuronal function, taurine and lactate, suggesting altered PFC metabolism i
55 ed release of the uncharged osmolytes [(3) H]taurine and myo-[(3) H]inositol, without major impact on
57 We speculate that organic osmolytes such as taurine and possibly novel processes such as extracellul
58 findings indicate that a combination of past taurine and recent indicine admixture-derived genetic re
60 ation products, as well as N-acetylcysteine, taurine and sulfo-conjugates in both rats and humans.
63 chromosome-level genome assemblies of Angus (taurine) and Brahman (indicine) cattle subspecies from c
64 rachidonoyl dopamine), NATau (N-arachidonoyl taurine), and NA-5HT (N-arachidonoyl serotonin), all dis
65 palmitic acid, L-tryptophan, kynurenic acid, taurine, and 25-hydroxyvitamin D compared with controls.
69 d on the reaction of naphthalene dialdehyde, taurine, and cyanide, yielding a fluorescent beta-isoind
73 comparisons among European taurine, African taurine, and indicine groups, we further identified 78 u
74 A panel of 4 biomarkers-formate, citrulline, taurine, and isocitrate-were identified as markers of SS
75 trong hard-sphere-like self-exclusion; urea, taurine, and myo-inositol have a tendency toward self-as
76 ake of compatible osmolytes such as betaine, taurine, and myo-inositol is a protective response share
80 ulators beta-phenylethylamine (beta-PEA) and taurine are important biogenic amines of the sympathetic
82 in the brain, in the local concentration of taurine at or near cellular spatial resolution in vivo o
83 ely, with significant differences in African taurine (AT) and Asian zebu backgrounds across chromosom
86 table, contrasting phenotypes of tick loads, taurine breeds carrying higher loads of the parasite tha
87 ween most of the Russian cattle and European taurine breeds, apart from a few breeds that shared ance
89 me multiple nutrients, including glucose and taurine, but prefer proline, and they actively synthesiz
91 of physiological concentrations of GABA and taurine, but, surprisingly, that receptor activity is on
92 d the potencies of glycine, beta-alanine and taurine by 9-, 6- and 3-fold respectively, and that of t
93 rate comparable to that of the oxidation of taurine by the TauD-J enzyme intermediate after adjustme
96 ns that have introgressed from indicine into taurine cattle under positive selection, harbouring gene
97 land, then ~120 years ago the first European taurine cattle were introduced to the island, and finall
98 n cattle diversity is generally dominated by taurine cattle, although elevated levels of indicine anc
99 entify one highly divergent locus in African taurine cattle, which is putatively linked to trypanotol
100 ted in the Nelore individual relative to the taurine cattle, while genes involved in lipid transport
103 their effects were assessed on MPO-mediated taurine chlorination and low-density lipoprotein oxidati
106 ding two novel products, that is, diclofenac taurine conjugate (DCF-M403) and unexpected diclofenac m
107 olic acid, which in vivo is converted to its taurine conjugate tauroursodeoxycholic acid (TUDC), is a
108 ition of chenodeoxycholic acid (CDCA) or its taurine conjugate, which was fully blocked by CFTR inhib
110 on of the structural isomers of glycine- and taurine-conjugated BAs and unconjugated tetra-hydroxy BA
114 port here a radiosynthesis of N-(11)C-methyl-taurine-conjugated bile acids and biodistribution studie
115 ers behave in a manner similar to endogenous taurine-conjugated bile acids in vivo and are thus promi
116 The radiosyntheses of the N-(11)C-methyl-taurine-conjugated bile acids proceeded with radiochemic
122 which were accompanied by increased hepatic taurine-conjugated cholic acid and beta-muricholic acid
126 developed and used to prepare N-(11)C-methyl-taurine conjugates derived from cholic, chenodeoxycholic
130 ts are mediated by milk-derived-fat-promoted taurine conjugation of hepatic bile acids, which increas
131 food-deprived animals, with a novel class of taurine-containing lipids and the essential polyunsatura
136 laskensis G20, which use isethionate but not taurine; corresponding knockout mutants of D. alaskensis
137 lysine, isoleucine, leucine, phenylalanine, taurine, cysteine, and glucose uptake rates to enhance h
139 eurons; 3) during normoxia GABA, glycine and taurine decreased GABA(A)Ralpha and GlyRalpha1 density i
141 in aquafeeds, but one of the limitations is taurine deficiency that can be especially detrimental fo
142 ally high, then fell, possibly indicative of taurine dependency in seals, and progressive depletion o
143 armacological blockade of VRACs, by cellular taurine depletion, by metabolic inactivation of glia wit
145 similarity to proteins annotated as alpha-KG:taurine dioxygenases (TauD), a well characterized member
149 ictive modeling calculations and showed that taurine-driven E-ring opening and increasing negative ch
150 -driven E-ring opening, we hypothesized that taurine-driven E-ring opening of bacteriochlorophyll der
151 ed from type 2 to type 1 for 1b (WST11) upon taurine-driven E-ring opening, we hypothesized that taur
156 uring sleep deprivation compared with sleep (taurine, formate, citrate, 3-indoxyl sulfate, carnitine,
157 iff base conjugate that the primary amine of taurine forms with retinaldehyde would readily hydrolyze
160 e of inulin, more bacterial deconjugation of taurine from primary bile acids was observed along with
161 n 0 (C-), 5 (T5), 10 (T10) or 20 (T20) added taurine (g/kg), while a control diet (C+) included two-f
163 nd free amino acids, and a large decrease of taurine, glucose, lactate, and creatine/phosphocreatine.
164 Some bioactive substances like coenzyme Q10, taurine, glutamine, creatine, creatinine, carnosine and
165 absolute amounts and mol% of certain AA (eg: Taurine, glutamine, tyrosine, phenylalanine) in the drie
166 -MS/MS), and thiols (homocysteine, cysteine, taurine, glutamylcysteine, total glutathione, and cystei
171 ribute to pathogenesis and that cysteine and taurine have the potential to serve as adjunctive treatm
172 e that the microbiota-associated metabolites taurine, histamine, and spermine shape the host-microbio
173 elenium, vitamin D(3), vitamin C, trytophan, taurine, histidine and hydroxyproline were below the ref
174 ere divided into two groups: gingiva with 1% taurine-hydrated collagen membrane (n = 8) and saline-hy
176 nvestigation of the 2OG-dependent oxygenase, taurine hydroxylase (TauD), revealed a strong link betwe
179 quantitative technique validation by imaging taurine in the cerebellum and hippocampus regions of the
181 resulted in the detection of hypotaurine or taurine in the reaction mixtures, suggesting the possibl
182 port findings that indicate a novel role for taurine in the regulation of voltage-gated delayed recti
184 n of radioactivity from [(35)S]cysteine into taurine, in primary murine astrocytes and neurons, and i
187 ing 508 individuals from 23 cattle breeds of taurine, indicine and mixed ancestry, including three br
188 s a key role in converting bile salt-derived taurine into H(2)S in the disease-associated gut bacteri
190 Combining numerous indirect measurements, taurine is known to play critical roles in brain functio
194 ur data reveal that inorganic S compounds or taurine is unlikely to serve as an S source during invas
195 roscopy, demonstrated increased abundance of taurine, isoglutamine, choline, lactate, phenylalanine a
203 otaurine without a corresponding increase in taurine levels, suggesting that oxidation of hypotaurine
207 itional copies in the indicine compared with taurine lineage and an indicus-specific extra copy of fa
208 ropean cattle are largely descended from the taurine lineage, gene flow from African cattle (partiall
211 Further, we apply the technique to image taurine loss from the vulnerable CA1 (cornus ammonis 1)
212 ed lipids, as well as antioxidant molecules [taurine (m/z 124.0068), uric acid (m/z 167.0210), ascorb
213 peak open probability (P(Open,peak)) of 0.4, taurine (maximal P(Open,peak) = 0.4), or the endogenous
214 creased levels of serotonin, tryptophan, and taurine may explain the antidepressive effect of acute s
216 lity, and simplicity of the enzyme-cleavable taurine motif promise new ways to promote the uptake of
219 ation between HPLC and ELISA for glycine and taurine (n = 10) showed regression coefficients of 0.97
221 osanoyl-taurine [NAT(24:0)] and N-eicosanoyl-taurine [NAT(20:0)]-as primary substrates for FAAH in mo
222 wo long-chain saturated NATs-N-tetracosanoyl-taurine [NAT(24:0)] and N-eicosanoyl-taurine [NAT(20:0)]
223 s, the N-acylethanolamines (NAEs) and N-acyl taurines (NATs), in central and peripheral tissues.
225 ents often present in energy drinks, such as taurine, niacin, and pyridoxine, is less well defined.
230 tly increased levels of lactate (P < 0.005), taurine (P < 0.005), and isoglutamine (P < 0.005) and de
231 nositol (mI), scyllo-inositol (sI), glycine, taurine, phosphoethanolamine (PE) and increase in the le
233 and metabolic changes in total creatine and taurine previously reported to be associated with amyloi
234 deficiency in the offspring decreases liver taurine production and associates with abrogation of a g
235 ity in the presence of combinations of GABA, taurine, propofol, allopregnanolone and/or the inhibitor
236 n of taurine to sulfoacetaldehyde by a known taurine:pyruvate aminotransferase is followed, unexpecte
238 s (VRACs), and it has been hypothesized that taurine released from glial cells is capable of inhibiti
239 -deficient offspring, oral administration of taurine rescued their growth retardation and osteoporosi
242 that the fatty acid analogue N-arachidonoyl taurine restores channel gating of many different mutant
245 keeping with its broad tissue distribution, taurine serves as a modulator of numerous basic processe
246 e themselves, such as pyridoxine/vitamin B6, taurine, some essential amino acids, and a conditionally
247 After UDCA removal cholestatic parameters, taurine species of cholic acid and chenodeoxycholic acid
252 CDO, and GOT1 expression were normalized by taurine supplementation, indicating that cysteine is not
254 ostweaning growth and bone formation through taurine synthesis and suggests potential therapies to in
258 istent with its role as an organic osmolyte, taurine synthesis was stimulated under hypertonic condit
260 lfonic acids: 2-aminoethane-1-sulfonic acid (taurine, T), 3-aminopropane-1-sulfonic acid (homotaurine
262 he acetyl group with the sulfonic amino acid taurine (Tau-LPFFD-NH2) and a second novel one in which
263 nome-wide copy number differences among five taurine (three Angus, one Holstein, and one Hereford) an
267 rea, nitrate, dimethylsulfoniopropionate and taurine transformation were identified that interlink me
270 xpression of glucose transporter 1 (GLUT-1), taurine transporter (TAUT), sodium-dependent neutral ami
271 al in the eighth transmembrane domain of the taurine transporter SLC6A6 was identified resulting in a
274 new epithelial formation was observed in 1% taurine-treated gingivectomy specimens, whereas incomple
275 vely, our findings indicate that adjuvantial taurine treatment has the potential to significantly imp
278 e current study, we showed that knockdown of taurine up-regulated gene 1 (TUG1) induces marked inhibi
279 of the conserved long noncoding RNAs MALAT1, taurine upregulated gene 1 (TUG1), maternally expressed
280 report that the long noncoding RNA (lncRNA) taurine-upregulated 1 (Tug1) contributes to CKD developm
285 d copepodamides, are polar lipids connecting taurine via an amide to isoprenoid fatty acid conjugate
286 in particular omega-3 fatty acids, selenium, taurine, vitamins D and B12, in the context of the devel
288 n of radioactivity from [(35)S]cysteine into taurine was observed in rat glioma cells as well as in p
289 ternofetal clearance of (14)C-MeAIB and (3)H-taurine was reduced and uterine arteries showed increase
290 rine, acetyl-CoA, and acetate), the level of taurine was significantly reduced, whereas the levels of
291 lux of uncharged osmolytes (myo-inositol and taurine) was suppressed by deletion of LRRC8A or LRRC8D,
293 aline, GABA, glutamine, alanine, glycine and taurine were separated and detected at concentrations si
294 an amino acid associated with tissue damage (taurine), which may be useful as a joint marker of the t
295 organic osmolyte 2-aminoethylsulfonic acid (taurine), which reduces liver endoplasmic reticulum stre
296 thesis involves conjugation with glycine and taurine, which promotes a high intraluminal micellar con
297 specific cysteic acid decarboxylase produces taurine, while hydrogen sulfide is recycled into cystein
300 the main cattle groups, we identify a major taurine x indicine cattle admixture event dated to circa