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1 ine into the third ventricle greatly reduced telencephalic 5-HT and resulted in decreased fundamental
4 imilar to human HPE, and that characteristic telencephalic and diencephalic signaling centers, the co
5 en show that molecular heterogeneity between telencephalic and hindbrain choroid plexi contributes to
6 ct-tracing retrograde labeling suggests that telencephalic and preoptic sbLPXRFa cells might represen
7 ard nomenclature that has been used for many telencephalic and related brainstem structures in birds
8 of preplate cells extend across diencephalo-telencephalic and striatocortical boundaries before the
9 ermore, the novel projections to area X from telencephalic and thalamic areas could be new and intere
10 EC LV as a bifurcation gate for feedforward (telencephalic) and feedback (entorhinal-hippocampal) sig
11 orebrain holosphere comprises Foxg1-positive telencephalic- and Foxg1-negative diencephalic territori
12 call for a revision of the current models of telencephalic angiogenesis and support novel roles for e
14 n (Dm) and the dorsal nucleus of the ventral telencephalic area (Vd), the teleost anatomical homologs
15 f multiplexed sensory representations in the telencephalic area Dp, the homolog of the olfactory cort
16 We investigated neuronal activity in the telencephalic area nidopallium caudolaterale (NCL) while
19 the intrapeduncular nucleus), most nonlimbic telencephalic areas were LAMP-poor (e.g., field L, the l
20 e olfactory bulbs, in pallial and subpallial telencephalic areas, and in some diencephalic nuclei.
21 ytokines and aromatase was measured, as were telencephalic aromatase activity and immunoreactive arom
26 lication of caspase inhibitors can protect a telencephalic brain area from neurodegeneration in vivo
27 birds that learn complex vocalizations have telencephalic brain regions that control vocal learning
32 s that abnormalities of developing Gli3(-/-) telencephalic cells in Gli3(-/-) mutants result from a c
33 growth factor 8 (Fgf8), the possibility that telencephalic cells lacking Foxg1 are intrinsically inco
34 ation of the proliferation state of anterior telencephalic cells supports a model for olfactory bulb
35 to identify some of the defects of Gli3(-/-) telencephalic cells that are likely to be autonomous by
38 Gli3 is to regulate the competence of dorsal telencephalic cells, preventing cells near to its bounda
40 cephalic induction reveals that FGFs promote telencephalic character and are strictly required to kee
41 nd bed nuclei of the stria terminalis; basal telencephalic cholinergic and non-cholinergic corticopet
42 nt for Isl1 in the development of restricted telencephalic cholinergic neurons and link the developme
52 us differences between these cells and their telencephalic counterparts, both in their gene expressio
53 s were found in the small anterior domain of telencephalic CPe (tCPe), but its large posterior domain
54 1 in thalamic axon responsiveness to ventral telencephalic cues, and demonstrate a role for CHL1 and
57 dendrin, a protein originally identified in telencephalic dendrites, is a constituent of the SD comp
58 f neurons in both murine neocortex and chick telencephalic derivatives are tetraploid, and that in th
60 FoxO localization in the nucleus, and by the telencephalic development factor FoxG1, which we show bi
61 ting hypothesis suggests that failed ventral telencephalic development in the absence of Foxg1 is due
62 The most prominent aspect of this delayed telencephalic development is a tremendous expansion of t
63 In mouse models, the roles for RA signals in telencephalic development remain unclear, partly because
65 hesized that, similar to what is observed in telencephalic development, Foxg1 directs development of
69 expansion states depended on ambient [bFGF], telencephalic developmental stage, and differential acti
70 is indispensable for formation of an intact telencephalic-diencephalic boundary and for preventing t
71 ween the telencephalon and diencephalon, the telencephalic/diencephalic junction (TDJ), is often indi
72 ctivated cell sorting analyses of phenotyped telencephalic dissociates show that approximately 80% of
74 ates from the preoptic area (POA), a ventral telencephalic domain adjacent to the diencephalic border
75 x3b;six7-deficient embryos; however, ventral telencephalic domains are smaller and dorsal domains are
78 egulation of this process originating at the telencephalic dorsal midline, where levels of secreted B
79 of interneuron precursors in the developing telencephalic eminences predicts the intrinsic physiolog
81 anded SVZ, probably accounts for most of the telencephalic enlargement in passerines such as the zebr
82 elopmental time course and cellular basis of telencephalic enlargement in zebra finches, and then to
84 iated Dravet-Syndrome and control iPSCs into telencephalic excitatory neurons or medial ganglionic em
89 t 24 hr postfertilization (hpf) demonstrated telencephalic expression of zswim6 and onset of midbrain
91 We further find that Six3 promotes ventral telencephalic fates through transient regulation of foxg
94 We show that transplantation of immature telencephalic GABAergic interneurons from the mouse medi
96 factors normally expressed ventrally in the telencephalic ganglionic eminences (Mash1, Dlx2 and Gsh2
97 that express the gene exclusively in dorsal telencephalic glutamatergic neurons (Glu-CB1 -RS) or GAB
98 CB1 receptor functions exclusively in dorsal telencephalic glutamatergic neurons and investigated end
99 rly and selective CB1 reexpression in dorsal telencephalic glutamatergic neurons but not forebrain GA
100 ry roles of CB1 receptor expressed in dorsal telencephalic glutamatergic neurons in synaptic plastici
102 hese data reveal that CB1 receptor in dorsal telencephalic glutamatergic neurons plays a sufficient r
103 on, the rescue of the CB1 receptor on dorsal telencephalic glutamatergic neurons prolonged the time c
106 to reliably generate cerebral organoids of a telencephalic identity and maintain long-term viability
107 neurons and neural progenitors with apparent telencephalic identity, whereas cells differentiated wit
108 f FGF signaling prior to and coincident with telencephalic induction reveals that FGFs promote telenc
112 terior commissure, in response to unilateral telencephalic input related to the drive for sleep.
114 ure and function before seizure onset in the telencephalic internal structural heterotopia (tish) rat
116 splay a massive reduction in the size of the telencephalic lobes and absence of dorsomedial telenceph
117 le to elicit normal responses of key ventral telencephalic marker genes in Foxg1(-/-) telencephalic t
120 hordal mesendodermal and prospective ventral telencephalic markers are expanded posteriorly, Shh expr
121 t some of the abnormal expression of ventral telencephalic markers previously described as being in t
125 requires intercellular communication at the telencephalic midline mediated by signaling proteins.
126 ated ectopic Shh signaling can impair dorsal telencephalic midline morphogenesis, and lead to non-cle
130 l for regulating interneuron allocation from telencephalic multipotent precursors are poorly understo
131 stablishing the apical-basal polarity of the telencephalic NE, which is needed for the expansion and
132 is plays in the seasonal reconstruction of a telencephalic neural circuit that controls song behavior
133 and in the morphology and physiology of the telencephalic neural circuit underlying production of le
135 gulating the differentiation and identity of telencephalic neural precursors derived from mouse and h
136 dition, we demonstrate that Activin provides telencephalic neural precursors with positional cues tha
137 , lineage commitment, and differentiation by telencephalic neural progenitor cells in vitro and in vi
140 lf-renewal, survival, and differentiation of telencephalic neural progenitors, and that dysfunctions
142 f hippocampal neurons and differentiation of telencephalic neural stem cells is modulated by nanoroug
143 of detrimental effects of glucocorticoids on telencephalic neural stem/progenitor cells (NSPCs), the
145 ted cytostasis during the development of the telencephalic neuroepithelium and in glioblastoma brain
146 rtical hem (the most caudomedial edge of the telencephalic neuroepithelium) and found that these mice
148 ces Foxg1's position as a major regulator of telencephalic neurogenesis and supports the idea that Fo
149 data also show that the onset and offset of telencephalic neurogenesis are both delayed in zebra fin
150 hat misexpression of Gsx2 at early stages of telencephalic neurogenesis favors the specification of s
153 evelopment and has been implicated in dorsal telencephalic neuronal and astroglia cell fate decisions
155 contrast, Sema3D appears to be attractive to telencephalic neurons that form the anterior commissure
160 , we also demonstrated a pallial origin of a telencephalic NG2 population, which in the olfactory bul
165 The amygdaloid complex represents a group of telencephalic nuclei and cortical areas that control emo
166 her with robust mel1b expression in multiple telencephalic nuclei and sensory systems, the results fu
167 nse ir-fibers innervate preoptic and ventral telencephalic nuclei homologous to paraventricular, late
169 Songbirds evolved a complex set of dimorphic telencephalic nuclei that are essential for the learning
173 eurons are continually incorporated into the telencephalic nucleus HVC (used as a proper name), a pre
174 rmis (Uva) is the sole thalamic input to the telencephalic nucleus HVC (used as a proper name), a sen
176 Synaptic interactions within the songbird telencephalic nucleus HVC are implicated in motor and au
177 cal infusion of caspase inhibitors rescues a telencephalic nucleus in the adult avian song control sy
178 uence on auditory activity in HVC and in the telencephalic nucleus interface (NIf), the main auditory
181 of anterior neural tissue, especially in the telencephalic, optic and hypothalamic primordia, and a d
182 caused profound mispatterning of the entire telencephalic-optic-hypothalamic field, such that the op
185 h factor (FGF) 8 is increased at the rostral telencephalic organizer, yet the FGF8 source was unchang
186 wever, direct neural connections between the telencephalic output of the song system and beak muscle
187 hh-independent pathway that is essential for telencephalic pallial (dorsal) specification during neur
189 Cholinergic fibers were observed in both the telencephalic pallium and the subpallium, in the thalamu
190 mammals are still uncertain for most of the telencephalic pallium in birds and thus the new pallial
192 f cells originated in the caudal pole of the telencephalic pallium, and a cell population that travel
193 nd thalamic-recipient sensory neurons of the telencephalic pallium, whereas high egr1 upregulation oc
194 ed tac3-expressing cells are also present in telencephalic parts, such as ventral (Vv) and supracomis
195 gs point away from Shh involvement in dorsal telencephalic patterning and encourage additional explor
196 roof plate-dependent Bmp signaling in dorsal telencephalic patterning and HPE and define novel candid
197 We investigated the role of the rostral telencephalic patterning centre, which secretes FGF mole
198 alon were severely impaired, suggesting that telencephalic patterning is more sensitive to alteration
201 tes with the (severe)dorsal-to-(mild)ventral telencephalic phenotype observed in Gli3(Xt/Xt) mice.
204 ut are dispensable for the survival of early telencephalic precursor cells, in which any one of three
205 delity at every level of motor control, from telencephalic premotor areas to superfast syringeal musc
206 d identification of the boundary between the telencephalic preoptic area, rich in Nkx2.1 expression,
207 t two spatially distinct and early-specified telencephalic progenitor pools marked by the homeodomain
208 lting from defective proliferation in dorsal telencephalic progenitors and extensive cell death.
209 f dorsal (pallial) from ventral (subpallial) telencephalic progenitors and the differentiation of cor
210 lig2(cre/+) mice to target embryonic ventral telencephalic progenitors and the oligodendrocyte lineag
211 e first characterized Shh-responding ventral telencephalic progenitors between E9.5 and E12.5 and fou
213 , Lhx2 regulates a regional-fate decision by telencephalic progenitors during a critical period that
215 on that ActN1 promoted FGF responsiveness in telencephalic progenitors prompted us to examine the eff
216 e of Neuron, Butt et al. show that Nkx2-1 in telencephalic progenitors regulates interneuron subtype
217 rmining regional-fate in the Emx1 lineage of telencephalic progenitors that generate cerebral cortex.
218 h to determine the specific contributions of telencephalic progenitors to the structures that compris
219 Here, we show that hESCs differentiate to telencephalic progenitors with a predominantly dorsal id
221 , as a total population, cardinal markers of telencephalic progenitors, are, in fact, molecularly het
222 isexpression promotes neurogenesis in dorsal telencephalic progenitors, the co-expression of Gsx2 wit
224 proach reveals new roles for RA signaling in telencephalic proliferation, survival and fate specifica
225 Sonic Hedgehog (Shh) also stimulates dorsal telencephalic proliferation, we propose a model whereby
226 Neuroprogenitor cells (NPCs) in several telencephalic proliferative regions of the mammalian bra
228 developmental potential of subregions of the telencephalic proliferative zone (PZ) to give rise to ne
229 ion (20 GW), they were also expressed in the telencephalic proliferative zones and the emerging white
231 primary visual cortex (V1) is the principal telencephalic recipient of visual input in humans and mo
232 ons, including the medial zone of the dorsal telencephalic region (Dm) and the dorsal nucleus of the
234 In the songbird, the secondary auditory telencephalic region caudal mesopallium (CM) contains ne
235 n and the number of axon varicosities in the telencephalic region proposed to be associated with aggr
236 ave implicated a number of mesencephalic and telencephalic regions in mediating these behaviors, we h
239 LAMP immunolabeling was prominent in many telencephalic regions previously noted as limbic in bird
240 lfactory cortex and the general expansion of telencephalic regions that communicate reciprocally with
242 visual, and lateral line systems, as well as telencephalic regions that have been compared to the amy
243 re detected in a number of mesencephalic and telencephalic regions, >50% of such neurons were located
244 Staining was most prominent in subpallial telencephalic regions, and diencephalic regions of the p
246 oepithelial progenitor pool of the posterior telencephalic roof, activated at postembryonic stages an
247 entifies Wnt/beta-catenin-activated from the telencephalic roof-as an Shh-independent pathway that is
248 ate-dependent gating of auditory activity in telencephalic sensorimotor structures important to learn
249 gene expression patterns are rescued on the telencephalic side of the TDJ but not in the diencephalo
250 r shh pallidal domain representing the basal telencephalic signaling center important for basal gangl
252 howed that production of Fgf8 by the rostral telencephalic signalling centre is required for the spec
253 ls and further emphasise the crucial role of telencephalic signalling centres in the generation of di
255 hx6 embryos, as well as in vitro in isotypic telencephalic slice cocultures obtained from E14.5 embry
258 imotor structures implicated in singing, the telencephalic song nucleus interface (NIf) and HVC.
259 lishment of staining patterns within rostral telencephalic song regions [area X and lateral magnocell
260 ctivity is observed during singing in HVC, a telencephalic song system nucleus that is essential for
262 rphogenetic proteins (BMPs), and an anterior telencephalic source of fibroblast growth factors (FGFs)
264 This region, area X, is embedded within a telencephalic structure considered homologous to the str
266 Differential expression was found in some telencephalic structures and positive signals for both p
267 nsequently, the upper jaw, nasal, ocular and telencephalic structures are absent, but the tongue and
268 ABA neurons of the cerebral cortex and other telencephalic structures are produced in the basal foreb
269 fect synaptic and cognitive functions within telencephalic structures such as the medial prefrontal c
270 spread projections of cholinergic neurons to telencephalic structures that themselves are highly inte
271 ques are found in the extracellular space of telencephalic structures, and have been shown to disrupt
272 g of the evolutionary relationships of these telencephalic structures, especially those of basally br
273 mally small and fails to develop dorsomedial telencephalic structures, including hippocampus and cort
274 lencephalic lobes and absence of dorsomedial telencephalic structures, including the cortical hem, wh
278 terneuron subtypes are derived from distinct telencephalic subdivisions, we have used an in vitro ass
281 triatum (MSt), septum, Area X, diencephalon, telencephalic subventricular zone (SVZ), and Purkinje ce
282 ral telencephalic marker genes in Foxg1(-/-) telencephalic tissue following a range of in vivo and in
284 ressed in the subventricular zone lining the telencephalic ventricles and in the rostral migratory st
285 re line to delete floxed-Rac1 alleles in the telencephalic ventricular zone (VZ) of mouse embryos.
286 eurons derive from radial glial cells in the telencephalic ventricular zone and not the medial gangli
287 ys we show that NSCs and INPs coexist in the telencephalic ventricular zone and that they can be pros
289 ined the transcriptome of lateral ventricle (telencephalic) versus fourth ventricle (hindbrain) choro
292 tzius cells that populate the surface of the telencephalic vesicles, an amygdaloid group of cells ori
296 ruct a "map" of proliferation throughout the telencephalic VZ, thereby allowing us to compare levels
297 tracortical area located in the rostromedial telencephalic wall (RMTW) that gives rise to several cel