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1 erase proteins), and the processing of TLC1 (telomerase RNA).
2  determine the overall architecture of human telomerase RNA.
3 hat spanned the template of the S. castellii telomerase RNA.
4 A, and mixed domain scaRNAs, as well as with telomerase RNA.
5 d in heterozygous combination with wild-type telomerase RNA.
6 een associated previously with the noncoding telomerase RNA.
7 act on the function of coexpressed wild-type telomerase RNA.
8 anscriptase protein (TERT) and the intrinsic telomerase RNA.
9 ment (helix II) from Tetrahymena thermophila telomerase RNA.
10 tending primers that form short hybrids with telomerase RNA.
11 bond with, for example, the P3 domain of the telomerase RNA.
12 OX4 paralogs, as well as Notch-1, LEF-1, and telomerase RNA.
13 lytic subunit in an inactive complex lacking telomerase RNA.
14 errant telomeres directed by mutant-template telomerase RNA.
15 s and upstream promoters similar to those of telomerase RNA.
16 al body on the intranuclear traffic route of telomerase RNA.
17 tending primers that form short hybrids with telomerase RNA.
18 incompatibility between human TERT and mouse telomerase RNA.
19  telomerase reverse transcriptase (TERT) and telomerase RNA.
20 hat regulates the production of mature human telomerase RNA.
21 tment of the exosome to snoRNAs and to human telomerase RNA.
22 ment found in ciliates is conserved in human telomerase RNA.
23  snRNA, snoRNA, RNase P, RNase MRP, Y RNA or telomerase RNA.
24 r1 functions in processing intron-containing telomerase RNA.
25 ween this domain and a quadruplex from human telomerase RNA.
26  been identified in human, yeast and ciliate telomerase RNAs.
27 nduced by telomere-uncapping mutant template telomerase RNAs.
28 iliates, define a minimal universal core for telomerase RNAs.
29 izosaccharomyces pombe telomerase RNA, TER1 (telomerase RNA 1), also contains a STE, which is essenti
30 instance, for the pseudoknot domain of human telomerase RNA, a native-like and a misfolded hairpin in
31 E, mutation led to severe destabilization of telomerase RNA, a reduction in telomerase activity, and
32 hat affect telomere length act by modulating telomerase RNA abundance, we used real-time reverse tran
33 t of telomere length genes act by modulating telomerase RNA abundance.
34 A, and that genetic depletion of p65 reduces telomerase RNA accumulation in vivo.
35 ry structure thought to be involved in human telomerase RNA accumulation in vivo.
36 essential RNA element derived from the human telomerase RNA activation domain.
37 e that contains an integral RNA subunit, the telomerase RNA and a catalytic protein subunit, the telo
38 ents of RNase P and RNase MRP, bind to yeast telomerase RNA and are essential constituents of the tel
39 o the architecture and coordination of human telomerase RNA and highlight where the RNA could be targ
40  report that at least a subfraction of human telomerase RNA and individual resident Cajal body RNAs i
41        Dyskerin binds the H/ACA box of human telomerase RNA and is a core telomerase subunit required
42  conclude that (i) quadruplex from the human telomerase RNA and its DNA analog both adopt a disc shap
43 e-molecule imaging unveils the life cycle of telomerase RNA and provides a framework to reveal how ca
44                                              Telomerase RNA and related noncoding RNAs require 3' end
45 .g., mRNA, ribosomal RNA, small nuclear RNA, telomerase RNA and so on).
46 tified that possessed all detectable cardiac telomerase RNA and telomerase activity.
47 nomers rather than higher-order multimers of telomerase RNA and telomerase reverse transcriptase.
48 ssential template/pseudoknot domain of human telomerase RNA and that inhibit telomerase function in v
49 cell extract is associated specifically with telomerase RNA, and that genetic depletion of p65 reduce
50     Disease-associated variants of the human telomerase RNA are expressed in heterozygous combination
51   These findings support loss of function of telomerase RNA as a general mechanism of human disease.
52          Thus, the CEH is essential in yeast telomerase RNA because it is needed to bind TERT to form
53 oilin involvement in the processing of human telomerase RNA both in vitro and in vivo.
54 he mutational analysis further suggests that telomerase RNA can function independent of the proposed
55 ss whether introducing 2'-O methylation into telomerase RNA can influence telomerase activity in vivo
56 on of telomere-length maintenance molecules [telomerase RNA component ( Terc; P < 0.01), P23 ( P = 0.
57 ound to regulate the maturation of the human telomerase RNA component (hTR), a noncoding RNA required
58  complex controls the stability of the human telomerase RNA component (hTR/TERC).
59                In addition, we confirmed the telomerase RNA component (TERC) as a gene associated wit
60 r telomerase reverse transcriptase (Tert) or telomerase RNA component (Terc) genes.
61                                          The telomerase RNA component (TERC) is a critical determinan
62 d DC cells overcome a critical limitation in telomerase RNA component (TERC) levels to restore telome
63 lomerase reverse transcriptase (TERT) or the telomerase RNA component (TERC) telomerase genes.
64 telomerase reverse transcriptase (TERT), the telomerase RNA component (TERC), and the TERC-binding pr
65                                              Telomerase RNA component (TERC), the RNA component and T
66 sm level in mice doubly null for Atm and the telomerase RNA component (Terc).
67 is required for the 3'-end maturation of the telomerase RNA component (TERC).
68 merase that oligoadenylates and destabilizes telomerase RNA component (TERC).
69   Here we show that genetic depletion of the telomerase RNA component (TR) in the zebrafish results i
70 able cell line overexpressing both the human telomerase RNA component and the N-terminally biotinylat
71 of NP oligonucleotide (GRN163) against human telomerase RNA component as a telomerase inhibitor and p
72 yethyl oligonucleotides complementary to the telomerase RNA component diffuse across cell membranes w
73  in the telomerase reverse transcriptase and telomerase RNA component genes have been observed at a h
74 stions regarding the mechanisms by which the telomerase RNA component supports tumorigenesis.
75 1 (rs9419958 P = 9.1 x 10(-11)) and with the telomerase RNA component TERC (rs1317082, P = 1.1 x 10(-
76  receptor tyrosine kinase, downregulates the telomerase RNA component TERC, confers genomic stability
77  Determination of the structure of the yeast telomerase RNA component TLC1 has been hampered by its l
78 omoter interactions (7SK), telomere biology (telomerase RNA component) and inflammatory gene regulati
79  DKC1, while heterozygous mutations in TERC (telomerase RNA component) and TERT (telomerase reverse t
80 h respect to both Wrn and Terc (encoding the telomerase RNA component), telomere dysfunction elicits
81                  Reduced levels of TERC, the telomerase RNA component, cause dyskeratosis congenita (
82                        Overexpression of the telomerase RNA component, hTR, demonstrated that this pr
83 UC1 and PyMT (MMT mice) but deficient in the telomerase RNA component, mTerc, on the C57BL/6 backgrou
84 ns of telomerase-deficient mice null for the telomerase RNA component, mTERC.
85 s new function for TERT does not require the telomerase RNA component, which encodes the template for
86  locus that includes TERC, which encodes the telomerase RNA component.
87 copying a short template sequence within its telomerase RNA component.
88 he pseudoknot, and potentially the predicted telomerase RNA conformation, affects polymerization to c
89                               All vertebrate telomerase RNAs contain a catalytically essential core d
90 n and the budding yeast Kluyveromyces lactis telomerase RNAs contain unusual triple-helical segments
91  reverse transcriptase to associate with the telomerase RNA depends on a highly structured region rat
92  in previously unassigned density as well as telomerase RNA domains essential for activity.
93          The effects of various mutations on telomerase RNA dynamics are also investigated.
94  Here, we engineer human and Tetrahymena cis-telomerase RNAs, each having a DNA primer covalently lin
95 ng was only partially dependent on TER1, the telomerase RNA, even though Est1 bound nucleotides 415-5
96 luding, for example, TERC, which encodes the telomerase RNA, exhibit extensive hypermethylation, wher
97                                              Telomerase RNA expression level may provide a clinically
98  suppression of mouse telomerase RNA reduced telomerase RNA expression, telomerase activity, and telo
99  we have mapped an essential binding site in telomerase RNA for TERT that is crucial to form the cata
100 , we identified seven conserved sequences in telomerase RNAs from Kluyveromyces budding yeasts.
101 e results, combined with previous studies on telomerase RNAs from other budding yeasts, vertebrates,
102 nd detected two novel point mutations in the telomerase RNA gene (TERC) in each family.
103            New data now suggest that a viral telomerase RNA gene encoded by Marek's disease virus (MD
104 a tlc1h mutant, the templating region of the telomerase RNA gene is altered so that telomerase adds t
105 splay anticipation and have mutations in the telomerase RNA gene.
106                     Here, we generated TERC (telomerase RNA) gene knockouts in telomerase positive ce
107 ecular dynamics simulations of the wild-type telomerase RNA hairpin.
108 eudoknot formation in the core region of the telomerase RNA has been demonstrated to be important for
109   A common secondary structure of vertebrate telomerase RNA has been proposed based on a phylogenetic
110                                   Vertebrate telomerase RNAs have three essential domains: the templa
111 ng RNA (siRNA) knockdown of endogenous human telomerase RNA (hTer) with expression of a mutant-templa
112 the core domain (residues 1 to 210) of human telomerase RNA (hTER).
113 ns an intrinsic templating RNA moiety (human telomerase RNA; hTER) and the core protein (human telome
114                                        Human telomerase RNA (hTERC) is thought to function as a dimer
115 stem were used to deliver APEX2 to the human telomerase RNA hTR with high specificity.
116 merase RNP and its two key components, human telomerase RNA (hTR) and human telomerase reverse transc
117                                          The telomerase RNA (hTR) and reverse transcriptase (hTERT) p
118                       Expression of the core telomerase RNA (hTR) and reverse transcriptase (hTERT) s
119 wo essential components of human telomerase, telomerase RNA (hTR) and telomerase reverse transcriptas
120 subcellular localization of endogenous human telomerase RNA (hTR) and telomerase reverse transcriptas
121  can be reconstituted in vitro with only the telomerase RNA (hTR) and telomerase reverse transcriptas
122  We determined previously that a novel human telomerase RNA (hTR) antagonist, GRN163L, inhibited the
123            Thermal denaturation of the human telomerase RNA (hTR) DeltaU177 pseudoknot and hTR p2b ha
124                     The H/ACA motif of human telomerase RNA (hTR) directs specific pathways of endoge
125 g target, and hTR-P2b is a part of the human telomerase RNA (hTR) essential for its activity.
126              It has been proposed that human telomerase RNA (hTR) interacts with dyskerin, prior to a
127  studies of disease-linked variants of human telomerase RNA (hTR) or telomerase reverse transcriptase
128 igate the kinetic folding pathways for human telomerase RNA (hTR) pseudoknot.
129                Biological stability of human telomerase RNA (hTR) relies on H/ACA proteins, but other
130         The biological accumulation of human telomerase RNA (hTR) requires hTR H/ACA domain assembly
131  (PARN) cause accumulation of extended human telomerase RNA (hTR) species and precipitate dyskeratosi
132  presence of an H/ACA motif within the human telomerase RNA (hTR) suggested that telomerase might uti
133                     The total level of human telomerase RNA (hTR) was invariant across the cell cycle
134 e stability of non-coding RNAs such as human telomerase RNA (hTR), but these effects do not explain t
135           Here, we describe a motif of human telomerase RNA (hTR), not previously characterized in a
136 ranscriptase (TERT) and the non-coding human telomerase RNA (hTR), which serves as a template for the
137 icroscopy to study the folded state of human telomerase RNA (hTR).
138 MS2 RNA tagging to image single molecules of telomerase RNA (hTR).
139 e transcriptase (hTERT) and associated human telomerase RNA (hTR).
140 demonstrate the canonical nuclear RNA [human telomerase RNA (hTR)] is not present in human mitochondr
141 eta-deletion protein competed for binding to telomerase RNA (hTR/TERC), thereby inhibiting endogenous
142                                        These telomerase RNAs identified from filamentous fungi displa
143 are as follows: (1) Ku specifically binds to telomerase RNA in a distinct, yet related, manner to how
144 ed macronuclei, p43 largely colocalizes with telomerase RNA in discrete foci.
145 er cell cycle-dependent sequestration of the telomerase RNA in nucleoli, a process that excludes telo
146 he function of the alignment domain of human telomerase RNA in sustaining catalytic activity in vitro
147 ) complex associates with and stabilizes the telomerase RNA in the cytoplasm and promotes its nuclear
148 e recent identification of the gene encoding telomerase RNA in the fission yeast Schizosaccharomyces
149 ns have all been shown to have low levels of telomerase RNA in their peripheral blood, providing dire
150 erase activity reconstitution with wild-type telomerase RNA in vitro.
151 upport of spliceosomes generating 3' ends of telomerase RNAs in other fungi.
152                     Nevertheless, nearly all telomerase RNAs, including those of H. sapiens and S. ce
153 (DC), wherein PARN deficiency leads to human telomerase RNA instability.
154   However, in the context of the full-length telomerase RNA, interference by other parts of the RNA p
155 gth and cell growth defects, suggesting that telomerase RNA is a critical direct or indirect Paf1C ta
156                                              Telomerase RNA is an essential component of telomerase,
157                                              Telomerase RNA is an integral component of telomerase.
158          A pseudoknot structure in the human telomerase RNA is conserved in all vertebrates and is es
159                     How the mature 3' end of telomerase RNA is generated has so far remained elusive.
160 he functionally essential domains in ciliate telomerase RNA is stem-loop IV, which strongly stimulate
161 A (snRNA), small nucleolar RNA (snoRNA), and telomerase RNA, is further hypermethylated at the exocyc
162 STE), which was discovered 13 y ago in human telomerase RNA, is required for telomerase activity, yet
163          Here we have demonstrated that such telomerase RNA knockdown in cancer cells does not cause
164 d not cause chromosome end-to-end fusions in telomerase RNA knockout mouse embryos despite progressiv
165                                        Mouse telomerase RNA lacks helix P1b, and the boundary is esta
166                        Twofold reductions in telomerase RNA levels cause telomere shortening in both
167 hermore, DKC1(S485G) mutation does not alter telomerase RNA levels.
168 sociated proteins TCAB1 and dyskerin and the telomerase RNA maturation component poly(A)-specific rib
169 undergoes the first cleavage reaction during telomerase RNA maturation.
170  point requires telomerase and indicate that telomerase RNA may be limiting in vivo.
171 ient overexpression of mutant-template human telomerase RNA (MT-hTer) to add mutant DNA to telomeres
172 ytoplasmic passage, the nuclear stability of telomerase RNA no longer depends on Mex67.
173 wild-type mice, similar to the reductions in telomerase RNA observed in TR heterozygotes.
174                                     Although telomerase RNAs of different organisms are very diverse
175                              By alignment of telomerase RNAs of Saccharomyces cerevisiae and six Kluy
176 r G4 formation in full-length cellular human telomerase RNA, offering important insights into its cel
177         Disruption of the helix P1b in human telomerase RNA or alteration of its distance from the te
178 articles are essential for ribosomal RNA and telomerase RNA processing and metabolism.
179                          Ku binding to yeast telomerase RNA promotes telomere lengthening and telomer
180 describe a set of interactions between human telomerase RNA, protein domains, and the substrate DNA t
181 ions on the structure and stability of human telomerase RNA pseudoknot and CR7 domains by using NMR a
182 complementary pair of catalytically inactive telomerase RNA pseudoknot mutants in combination with a
183  that the distance between the 3' end of the telomerase RNA pseudoknot region and the 5' end of the D
184  base changes in a highly conserved putative telomerase RNA pseudoknot.
185 erved for the Kluyveromyces lactis and human telomerase RNA pseudoknots.
186 interfering RNA specifically targeting human telomerase RNA rapidly inhibits the growth of human canc
187 able, ribozyme-mediated suppression of mouse telomerase RNA reduced telomerase RNA expression, telome
188 ncoding telomerase reverse transcriptase and telomerase RNA, respectively, cause autosomal dominant d
189 hering Sir4 directly to Ku-binding-defective telomerase RNA restores otherwise-shortened telomeres to
190 cleotide pseudoknot from a distantly related telomerase RNA results in a functional telomerase enzyme
191                   Phylogenetic comparison of telomerase RNA sequences from several budding yeasts rev
192 enerally, our results support a role for the telomerase RNA serving as a scaffold for binding key pro
193     Mammalian H/ACA small nucleolar RNAs and telomerase RNA share common sequence and secondary struc
194 nt to the template region of human and mouse telomerase RNA significantly altered telomerase processi
195      The 3' end of Schizosaccharomyces pombe telomerase RNA (SpTER1) is generated by spliceosomal cle
196                       Binding of Tetrahymena telomerase RNA stem IV to TERT enhances nucleotide addit
197 Ps) we have identified a region of the human telomerase RNA subunit (hTR) approximately 100 nt downst
198  in vitro have revealed sequences within the telomerase RNA subunit (TER) that are required to establ
199  identified a precursor of the fission yeast telomerase RNA subunit (TER1) and demonstrated that the
200  study, we establish additional roles of the telomerase RNA subunit by demonstrating that RNA motifs
201  Saccharomyces cerevisiae and in humans, the telomerase RNA subunit is bound by Ku, a ring-shaped pro
202                 The Saccharomyces cerevisiae telomerase RNA subunit is encoded by the TLC1 gene.
203                                 The integral telomerase RNA subunit templates the synthesis of telome
204 stion, we engineered two mutant forms of the telomerase RNA subunit that contain DNA only in the temp
205 ubunit, hTERT, and key elements of the human telomerase RNA subunit, hTR.
206  of the four conserved elements in the yeast telomerase RNA subunit, TLC1, disrupts activity, the RNA
207 py only a short template sequence within the telomerase RNA subunit.
208                                              Telomerase RNA subunits are phylogenetically highly dive
209 ractions of PCBP2 KH1 with telomeric DNA and telomerase RNA suggest that PCBPs may participate in mec
210 Inhibition of telomerase activity with human telomerase RNA-targeted antisense agents, and in particu
211 se consists of two essential components, the telomerase RNA template (TR) and telomerase reverse tran
212 -methoxyethyl oligonucleotide that binds the telomerase RNA template and acts as a potent inhibitor.
213    We observe that LNAs complementary to the telomerase RNA template are potent and selective inhibit
214          Heterozygous mutations of the human telomerase RNA template gene (TERC) have been described
215 t repeats defining the ends of the K. lactis telomerase RNA template in telomerase translocation, we
216  overexpression of TERT in cells lacking the telomerase RNA template is also ineffective in preventin
217 ce lacking telomerase (for example, mTR(-/-) telomerase RNA template mutants) provide a model for inv
218                     Our results suggest that telomerase RNA template sequence is a key determinant of
219 thology in later-generation mice lacking the telomerase RNA template Terc, including acceleration of
220 yet poorly understood, mechanism whereby the telomerase RNA template translocates and realigns with t
221 erase catalytic component) and TERC/hTR (the telomerase RNA template) were measured using quantitativ
222 d in a cells lacking TERT but containing the telomerase RNA template, increases their resistance to a
223 ion occurs between DNA interactions with the telomerase RNA template, the active site in the telomera
224 ends of linear chromosomes using an integral telomerase RNA (TER) and telomerase reverse transcriptas
225 peat DNA at their 3'-ends, using an integral telomerase RNA (TER) and telomerase reverse transcriptas
226  Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) assemble as part of a holoenzyme th
227 rein the binding of p65 to stems I and IV of telomerase RNA (TER) causes a conformational change that
228 ase is a ribonucleoprotein with an intrinsic telomerase RNA (TER) component.
229  Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) function together to create a uniqu
230  telomerase reverse transcriptase (TERT) and telomerase RNA (TER) have been hypothesized to account f
231 ven proteins and the TERT-binding regions of telomerase RNA (TER) have been localized by affinity lab
232                                              Telomerase RNA (TER) is an essential component of the te
233                                              Telomerase RNA (TER) provides the template for replicati
234 na telomerase comprises a ternary complex of telomerase RNA (TER), telomerase reverse transcriptase (
235 ain a telomerase reverse transcriptase and a telomerase RNA (TER), which together provide the minimal
236  telomerase reverse transcriptase (TERT) and telomerase RNA (TER).
237 (TERT) copies a template within the integral telomerase RNA (TER).
238 odification and for cellular accumulation of telomerase RNA (TER).
239 anscriptase (TERT) protein and an associated telomerase RNA (TER).
240  telomerase reverse transcriptase (TERT) and telomerase RNA (TER).
241 omerase reverse transcriptase (TERT) and the telomerase RNA (TER).
242 elomerase reverse transcriptase (TERT) and a telomerase RNA (TER).
243 se transcriptase requires a multidomain RNA (telomerase RNA, TER), which includes an integral RNA tem
244                            The fission yeast telomerase RNA (TER1) precursor harbors an intron immedi
245       In the yeast Kluyveromyces lactis, the telomerase RNA (Ter1) template has 30 nucleotides of per
246 vage reaction generates the mature 3' end of telomerase RNA (TER1, the functional RNA encoded by the
247 We report that the Schizosaccharomyces pombe telomerase RNA, TER1 (telomerase RNA 1), also contains a
248                                        Human telomerase RNA TERC occupies telomeres and Wnt pathway g
249                       Mutations in the human telomerase RNA (TERC) occur in autosomal dominant dysker
250 ng the telomerase reverse transcriptase, the telomerase RNA (TERC), and dyskerin.
251 due to a mutation in the gene-encoding human telomerase RNA (TERC), resulting in telomere shortening.
252 ve identified nucleotide determinants in the telomerase RNA that are responsible for this difference
253          Motifs have been defined within the telomerase RNA that contribute to mature RNA accumulatio
254 al residues in the alignment domain of human telomerase RNA that contribute to the activity and proce
255                Here, we identify a region of telomerase RNA that is necessary for both correct 5' tem
256 ement of a 95-nucleotide region of the yeast telomerase RNA that is required for Est2 interaction wit
257 tant nucleotides in the pseudoknot domain of telomerase RNA that potentially mediate the incompatibil
258 periments identify essential residues of the telomerase RNA that regulate telomerase activity and pro
259  other yeast species were found to also have telomerase RNAs that encode relatively long 7- to 10-nuc
260  for mediating protein interactions with the telomerase RNA TLC1 have been identified.
261 time that the yeast Saccharomyces cerevisiae telomerase RNA TLC1 likewise forms dimers in vitro.
262 rase protein Est2p even in cells lacking the telomerase RNA TLC1, or the telomerase-associated protei
263 p sequencing, we show that the budding yeast telomerase RNA (TLC1 RNA) is spatially segregated to the
264 r telomeres to determine the levels of their telomerase RNA (TLC1) abundance.
265 1 subunits via independent interactions with telomerase RNA (TLC1) and telomeric proteins Sir4 and Cd
266 s cerevisiae, distinct regions of the 1.2-kb telomerase RNA (TLC1) bind to the catalytic subunit Est2
267 inding to double-stranded DNA (dsDNA) and to telomerase RNA (TLC1) promotes Ku's telomeric functions
268 acterization of the Saccharomyces cerevisiae telomerase RNA (TLC1) pseudoknot identified tertiary str
269 ntral domain of the Saccharomyces cerevisiae telomerase RNA (TLC1) that are important for telomerase
270 oknot structure) of Saccharomyces cerevisiae telomerase RNA (TLC1).
271 157-nucleotide (nt) Saccharomyces cerevisiae telomerase RNA, TLC1, is rapidly evolving, the central c
272 s at template positions 474-476 of the yeast telomerase RNA, TLC1.
273 o Cajal bodies, resulting in misdirection of telomerase RNA to nucleoli, which prevents telomerase fr
274 L), a time when Cajal bodies fail to deliver telomerase RNA to telomeres.
275 d in mutation carriers, genomically extended telomerase RNA (TR) accumulated at the expense of mature
276 the telomerase reverse transcriptase (TERT), telomerase RNA (TR) and other telomerase-associated prot
277 omposition and only moderately correlated to telomerase RNA (TR) binding.
278 e transcriptase (RT) containing an intrinsic telomerase RNA (TR) component.
279                                              Telomerase RNA (TR) from different groups of species var
280                     The sensitive imaging of telomerase RNA (TR) in living cells is crucial for impro
281 ver capable of predicting core structures of telomerase RNA (TR) in yeast genomes.
282 er of the two core components of telomerase, telomerase RNA (TR) or the catalytic protein component t
283 ends of linear chromosomes using an integral telomerase RNA (TR) template.
284  telomerase reverse transcriptase (TERT) and telomerase RNA (TR) that provides the template for telom
285 everse transcriptase containing an intrinsic telomerase RNA (TR) which provides the template for telo
286 rse transcriptase (TERT) and template in the telomerase RNA (TR), thereby helping to maintain genome
287 leoprotein complex, where the RNA component [telomerase RNA (TR)] not only provides the template for
288  a reverse transcriptase and an RNA subunit (telomerase RNA [TR]).
289 re we show that in Schizosaccharomyces pombe telomerase RNA transcripts must be processed to generate
290            Reconstitution of V867M hTERT and telomerase RNAs (TRs) with mutated template sequences re
291 ately after transcription, newly synthesized telomerase RNAs undergo one round of nucleo-cytoplasmic
292 te the biological function of disease-linked telomerase RNA variants and their impact on the function
293                                 We find that telomerase RNA variants discovered in patients with dysk
294  between BC200 and the quadruplex-containing telomerase RNA was confirmed by pull-down assays of the
295 tein p65 induces structural rearrangement of telomerase RNA, which in turn directs the binding of the
296 rRNA, U small nuclear RNA (snRNA), and human telomerase RNA, which is altered upon treatment with DNA
297                        Recombinant p43 binds telomerase RNA with low-nanomolar affinity in vitro, rec
298 iation with vaults, while the association of telomerase RNA with the telomerase complex is independen
299                                        Mouse telomerase RNAs with mutations that disrupted base pairi
300 used to determine the global organization of telomerase RNA within catalytically active holoenzymes.

 
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