ライフサイエンスコーパス: telomerase reverse transcriptase

1 humans, rather than endogenous mTERT (mouse telomerase reverse transcriptase).

2 erase RNA; hTER) and the core protein (human telomerase reverse transcriptase).

3 ) decreases the mRNA expression of the human telomerase reverse transcriptase.

4 the MRP ribonucleoprotein ribozyme and human telomerase reverse transcriptase.

5 form stable complexes with the TEN domain of telomerase reverse transcriptase.

6 higher-order multimers of telomerase RNA and telomerase reverse transcriptase.

7 -circle formation in normal cells expressing telomerase reverse transcriptase.

8 he synthesis of the telomeric repeats by the telomerase reverse transcriptase.

9 and T-motif in the RNA-binding domain of the telomerase reverse transcriptase.

10 f two genes, asparagine synthetase and human telomerase reverse transcriptase.

11 nds to a peptide sequence derived from human telomerase reverse transcriptase.

12 tative polymerase chain reaction using human telomerase reverse transcriptase.

13 otide that targets the RNA template of human telomerase reverse transcriptase.

14 The templating RNA is the core of the telomerase reverse transcriptase.

15 and P6.1 to correctly fold and interact with telomerase reverse transcriptase.

16 nts with heterozygous mutations in TERT, the telomerase reverse transcriptase, a 50% reduction in tel

17 ligo also inhibited mRNA expression of human telomerase reverse transcriptase, a catalytic subunit of

18 The telomerase reverse transcriptase adds de novo DNA repeat

19 n Atm(-/-) mice engineered with an inducible telomerase reverse transcriptase allele.

20 Telomerases from all organisms contain a telomerase reverse transcriptase and a telomerase RNA (T

21 oblasts transduced with genes encoding human telomerase reverse transcriptase and doxycycline-inducib

22 rmore, we showed that reducing expression of telomerase reverse transcriptase and telomerase activity

23 Mutations in the telomerase reverse transcriptase and telomerase RNA comp

24 tations in the genes hTERT and hTR, encoding telomerase reverse transcriptase and telomerase RNA, res

25 ikely to change conformation in complex with telomerase reverse transcriptase and that it provides a

26 tumor antigen vaccine derived from the human telomerase reverse transcriptase and the antiapoptotic p

27 the former encodes the catalytic subunit of telomerase reverse transcriptase and the latter may play

28 Thus, p43 joins the telomerase reverse transcriptase and the yeast proteins

29 nent and the N-terminally biotinylated human telomerase reverse transcriptase and using a newly devel

30 riction decreased expression of hTERT (human telomerase reverse transcriptase) and increased expressi

31 expressed higher levels of K5, CD133, Oct4, telomerase reverse transcriptase, and C-X-C chemokine li

32 iched for expression of Ki-67, ZAP-70, human telomerase reverse transcriptase, and telomerase activit

33 ry, these data suggest that cells expressing telomerase reverse transcriptase are not a progenitor-ce

34 tension (CTE) domain of Arabidopsis thaliana telomerase reverse transcriptase as baits to screen an A

35 d beta1 integrins, DeltaNp63alpha, CD44, and telomerase reverse transcriptase, as well as decreased N

36 ted from chimera mice expressed collagen and telomerase reverse transcriptase but not alpha-smooth mu

37 n) were identified in TERT, the gene for the telomerase reverse transcriptase catalytic enzyme, among

38 ertion in fingers domain" (IFD) in the human telomerase reverse transcriptase catalytic subunit (hTER

39 ll-known "telomere disorder." RMRP binds the telomerase reverse transcriptase (catalytic subunit) in

40 ular and cytogenetic features of the chicken telomerase reverse transcriptase (chTERT) gene and prote

41 it is quickly silenced, specifically due to telomerase reverse transcriptase component (TERT) down-r

42 use myocardium, and transgenic expression of telomerase reverse transcriptase conferred protection fr

43 lmonary fibrosis by activation of fibroblast telomerase reverse transcriptase-dependent proliferation

44 for malignant behavior, expression of human telomerase reverse transcriptase enabled cells from seri

45 lls, whereas interleukin-31 strongly induced telomerase reverse transcriptase expression in fibroblas

46 report that BRCA1 knockdown causes increased telomerase reverse transcriptase expression, telomerase

47 The organization of the t/PK on telomerase reverse transcriptase for medaka and human is

48 ss various N-terminal fusion proteins of the telomerase reverse transcriptase from its endogenous loc

49 f renal tumor-associated antigens, including telomerase reverse transcriptase, G250, and oncofetal an

50 -Myc can activate transcription of the human telomerase reverse transcriptase gene (hTERT), we addres

51 oted c-Myc-dependent expression of the human telomerase reverse transcriptase gene (hTERT).

52 e hotspot integrations, such as those in the telomerase reverse transcriptase gene (TERT) promoter, a

53 ty, which is accompanied by induction of the telomerase reverse transcriptase gene (TERT).

54 hromosomal region at 5p15.33 proximal of the telomerase reverse transcriptase gene (TERT).

55 ecruited by Myc to the promoter of the human telomerase reverse transcriptase gene, and p300/CBP stim

56 mice was not affected by inactivation of the telomerase reverse transcriptase gene, indicating that e

57 ome clone containing the entire hTERT (human telomerase reverse transcriptase) gene was introduced in

58 in TERC (telomerase RNA component) and TERT (telomerase reverse transcriptase) have been found in aut

59 When Fancc(-/-) mice were crossed into a telomerase reverse transcriptase heterozygous or null ba

60 The human telomerase reverse transcriptase hTERT is highly express

61 therapy, the immunological properties of the telomerase reverse transcriptase hTERT suggest that the

62 Here, we demonstrate that human telomerase reverse transcriptase (hTERT) activates vascu

63 the core components of telomerase, the human telomerase reverse transcriptase (hTERT) and associated

64 dopts a new conformation on binding to human telomerase reverse transcriptase (hTERT) and reconstitut

65 LA-DR-restricted peptides derived from human telomerase reverse transcriptase (hTERT) and referred as

66 Higher expression of human telomerase reverse transcriptase (hTERT) and subsequent

67 , the cells were exposed to retroviral human telomerase reverse transcriptase (hTERT) and/or SV40 lar

68 Mutations in the gene for telomerase reverse transcriptase (hTERT) are associated

69 S signaling pathways and activation of human telomerase reverse transcriptase (hTERT) are common in h

70 expression and telomerase activity of human telomerase reverse transcriptase (hTERT) are hallmarks o

71 The mRNA and promoter activities of human telomerase reverse transcriptase (hTERT) are stimulated

72 Expression of human telomerase reverse transcriptase (hTERT) catalytic subun

73 lects E6-enhanced transcription of the human telomerase reverse transcriptase (hTERT) catalytic subun

74 ce mechanism, ALT+ human fibroblasts require telomerase reverse transcriptase (hTERT) for tumor forma

75 optical methods to measure changes in human telomerase reverse transcriptase (hTERT) gene expression

76 The endogenous human telomerase reverse transcriptase (hTERT) gene is repress

77 The human telomerase reverse transcriptase (hTERT) gene is repress

78 s to and regulates the activity of the human telomerase reverse transcriptase (hTERT) gene promoter.

79 e ectopic expression of telomerase via human telomerase reverse transcriptase (hTERT) gene transfecti

80 so by transcriptionally activating the human telomerase reverse transcriptase (hTERT) gene, which enc

81 Transcriptional activation of the human telomerase reverse transcriptase (hTERT) gene, which rem

82 BV and three HPV integrations into the human telomerase reverse transcriptase (hTERT) gene.

83 G-quadruplexes in the promoter of the human telomerase reverse transcriptase (hTERT) gene.

84 increased mRNA expression of CSF1R in human telomerase reverse transcriptase (hTERT) immortalized hu

85 of endogenous human telomerase RNA (hTR) and telomerase reverse transcriptase (hTERT) in HeLa cervica

86 in reaction (RT-PCR) for expression of human telomerase reverse transcriptase (hTERT) in mediastinal

87 to knock down factors cooperating with human telomerase reverse transcriptase (hTERT) in the immortal

88 onal conversion, whereas expression of human telomerase reverse transcriptase (hTERT) induces it.

89 Human telomerase reverse transcriptase (hTERT) is also often o

90 The transcriptional activation of human telomerase reverse transcriptase (hTERT) is an important

91 mechanisms governing expression of the human telomerase reverse transcriptase (hTERT) is important fo

92 Human telomerase reverse transcriptase (hTERT) is localized to

93 The human telomerase reverse transcriptase (hTERT) is nearly unive

94 Human telomerase reverse transcriptase (hTERT) is overexpresse

95 Human telomerase reverse transcriptase (hTERT) is overexpresse

96 s of the active full-length isoform of human telomerase reverse transcriptase (hTERT) may be expresse

97 analyses showed that leptin increased human telomerase reverse transcriptase (hTERT) mRNA expression

98 Although Tax impaired induction of human telomerase reverse transcriptase (hTERT) mRNA in respons

99 ,25(OH)(2)VD(3) decreases the level of human telomerase reverse transcriptase (hTERT) mRNA, the catal

100 Human telomerase reverse transcriptase (hTERT) plays a key rol

101 to show that FTSECs immortalized with human telomerase reverse transcriptase (hTERT) plus SV40 large

102 sid for enhanced tumor transduction, a human telomerase reverse transcriptase (hTERT) promoter for tu

103 The human telomerase reverse transcriptase (hTERT) promoter has be

104 s in the regulation of the activity of human telomerase reverse transcriptase (hTERT) promoter in res

105 al system, we recently showed that the human telomerase reverse transcriptase (hTERT) promoter induce

106 tly demonstrated that E6 activates the human telomerase reverse transcriptase (hTERT) promoter via a

107 l replication, is under control of the human telomerase reverse transcriptase (hTERT) promoter.

108 Telomerase reverse transcriptase (hTERT) represents an a

109 ing network consistent with a model of human telomerase reverse transcriptase (hTERT) repression in A

110 unction mutations in the TEN-domain of human telomerase reverse transcriptase (hTERT) that disrupt th

111 expressed transcriptional regulator of human telomerase reverse transcriptase (hTERT) that is targete

112 established that hTR remains bound to human telomerase reverse transcriptase (hTERT) throughout all

113 a gene (pRb) and ectopic expression of human telomerase reverse transcriptase (hTERT) to immortalize

114 e we used retroviral overexpression of human telomerase reverse transcriptase (hTERT) to immortalize

115 Upregulation of human telomerase reverse transcriptase (hTERT) transcription a

116 of Bmi-1 in MECs led to activation of human telomerase reverse transcriptase (hTERT) transcription a

117 The human telomerase reverse transcriptase (hTERT) utilizes a temp

118 atalytic component of human telomerase human telomerase reverse transcriptase (hTERT), and colonies w

119 of p53, transcriptional activation of human telomerase reverse transcriptase (hTERT), and degradatio

120 f human telomerase, telomerase RNA (hTR) and telomerase reverse transcriptase (hTERT), are recruited

121 iated by the induced overexpression of human telomerase reverse transcriptase (hTERT), has permitted

122 The catalytic subunit of telomerase, human telomerase reverse transcriptase (hTERT), is overexpress

123 ng cyclin-dependent kinase (Cdk) 4 and human telomerase reverse transcriptase (hTERT), resulting in c

124 nk between HMGA2 and the regulation of human telomerase reverse transcriptase (hTERT), the catalytic

125 Human telomerase reverse transcriptase (hTERT), the catalytic

126 h the transcription and translation of human telomerase reverse transcriptase (hTERT), the catalytic

127 We present evidence that normal and human telomerase reverse transcriptase (hTERT)-immortalized hu

128 Here we characterize the response of human telomerase reverse transcriptase (hTERT)-immortalized no

129 We show here that human telomerase reverse transcriptase (hTERT)-immortalized pr

130 ressor pathways in NHUC and to express human telomerase reverse transcriptase (hTERT).

131 cted with a retroviral vector encoding human telomerase reverse transcriptase (hTERT).

132 e expression of its enzymatic subunit, human telomerase reverse transcriptase (hTERT).

133 or telomere synthesis, which is catalyzed by telomerase reverse transcriptase (hTERT).

134 rmal human fibroblast (NHF) expressing human telomerase reverse transcriptase (hTERT).

135 onents, human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT).

136 induction of the telomerase component human telomerase reverse transcriptase (hTERT); T cell activat

137 ein catalytic component of telomerase [human telomerase reverse transcriptase (hTERT)] are required f

138 n of the telomerase catalytic subunit [human telomerase reverse transcriptase (hTERT)] expression abr

139 Human telomerase reverse transcriptase (hTERT; the catalytic p

140 is the transcriptional upregulation of human telomerase reverse transcriptase, hTERT, and the resulta

141 n of the telomerase catalytic subunit (human telomerase reverse transcriptase; hTERT) in human activa

142 Human telomerase reverse transcriptase (hTRT) is preferentiall

143 1delta) blocks primary ciliogenesis in human telomerase reverse transcriptase immortalized retinal pi

144 orm of CDK4 or knockdown of p16 in the human telomerase reverse transcriptase-immortalized NPE cell l

145 In human telomerase reverse transcriptase-immortalized NPE cells,

146 n of TRF2 expression in MNs and knock-out of telomerase reverse transcriptase in NPCs increased their

147 g the catalytic subunit of telomerase (human telomerase reverse transcriptase) in primary human mamma

148 sentation of a universal self-tumor antigen, telomerase reverse transcriptase, in human tumor cells d

149 be mediated through POT1/TRF2 and via human telomerase reverse transcriptase inhibition through JNK

150 The telomerase protein component TERT (telomerase reverse transcriptase) interacts with BRG1 (a

151 The template for telomerase reverse transcriptase is within the RNA subun

152 the gene encoding its catalytic subunit, the telomerase reverse transcriptase, is established as the

153 hTERT, the human telomerase reverse transcriptase, is highly expressed in

154 s well as the effect that over-expression of telomerase reverse transcriptase may have on the replica

155 ted the 3-prime untranslated region of human telomerase reverse transcriptase mRNA and decreased its

156 HIF is sufficient to induce telomerase reverse transcriptase mRNA and telomerase act

157 ability of 1,25(OH)(2)D(3) to decrease human telomerase reverse transcriptase mRNA and to suppress ov

158 f IRF-4 results in decreased levels of TERT (telomerase reverse transcriptase) mRNA and telomerase ac

159 s and in carcinoma progression, an inducible telomerase reverse transcriptase (mTert) allele was cros

160 ation of slowly cycling ISCs marked by mouse telomerase reverse transcriptase (mTert) expression that

161 tation and telomere dysfunction [produced by telomerase reverse transcriptase (mTERT) gene knockout].

162 The enzyme telomerase reverse transcriptase (mTert) regulates telom

163 ein (GFP), driven by the promoter for murine telomerase reverse transcriptase (mTert), which is a nec

164 We therefore generated mouse telomerase reverse transcriptase (mTert)-GFP-transgenic

165 Here, we uncovered that telomerase reverse transcriptase null (Tert(-/-)) mESCs

166 oding a 4-hydroxytamoxifen (4-OHT)-inducible telomerase reverse transcriptase-oestrogen receptor (TER

167 CRISPR/Cas9 knockout of human telomerase reverse transcriptase or treatment with the t

168 perature-sensitive large T antigen and human telomerase reverse transcriptase (OSEtsT/hTERT).

169 of four genetic alterations, including human telomerase reverse transcriptase overexpression, bypass

170 Myc E-box-mediated transactivation and human telomerase reverse transcriptase promoter activity, in a

171 em TTS (TTF1 gene under the control of human telomerase reverse transcriptase promoter and human surf

172 te that Pyk2 is capable of driving the human telomerase reverse transcriptase promoter, resulting in

173 telomerase domain-complementation assays for telomerase reverse transcriptase protein (TERT) and RNA

174 s of two essential components, the catalytic telomerase reverse transcriptase protein (TERT) and the

175 te within its integral RNA subunit (hTR) and telomerase reverse transcriptase protein (TERT) to accom

176 The telomerase reverse transcriptase protein TERT has recent

177 erves to repress the production of the human telomerase reverse transcriptase protein.

178 to assemble telomerase enzymes with variant telomerase reverse transcriptase proteins.

179 The specialized telomerase reverse transcriptase requires a multidomain

180 The expression of human telomerase reverse transcriptase restored telomerase act

181 Using Chlamydomonas and human telomerase reverse transcriptase-retinal pigment epithel

182 of 5-MeCITP bound to the Tribolium castaneum telomerase reverse transcriptase reveals an atypical int

183 Subsequently, annealing of the telomerase reverse transcriptase RNA-template (guide RNA

184 rentiation family), catalytic subunit of rat telomerase reverse transcriptase (rTERT), and proliferat

185 studies utilizing a combination of BRCA1 and telomerase reverse transcriptase small interfering RNAs

186 e first characterize the gene coding for the telomerase reverse transcriptase subunit PpTERT in P. pa

187 d advantages of the TRAIL gene and the human telomerase reverse transcriptase target, Ad/gTRAIL can b

188 to telomeres through an association with the telomerase reverse transcriptase TERT.

189 HCC, the most frequently mutated genes were telomerase reverse transcriptase (TERT) (58.1%), catenin

190 onucleoprotein telomerase, which comprises a telomerase reverse transcriptase (TERT) and a telomerase

191 ng telomeric repeats using an active site in telomerase reverse transcriptase (TERT) and an integral

192 elomerase, a ribonucleoprotein consisting of telomerase reverse transcriptase (TERT) and an integrall

193 DNA-interacting subunits other than telomerase reverse transcriptase (TERT) and telomerase R

194 ns two essential components for catalysis, a telomerase reverse transcriptase (TERT) and telomerase R

195 Telomerase reverse transcriptase (TERT) and telomerase R

196 Telomerase reverse transcriptase (TERT) and telomerase R

197 critical for catalytic activity, the protein telomerase reverse transcriptase (TERT) and telomerase R

198 Telomerase minimally comprises the catalytic telomerase reverse transcriptase (TERT) and telomerase R

199 Telomerase contains a catalytic core of telomerase reverse transcriptase (TERT) and telomerase R

200 Mutations in the genes encoding telomerase reverse transcriptase (TERT) and telomerase's

201 ' ends of linear chromosomes, using a unique telomerase reverse transcriptase (TERT) and template in

202 ex, the catalytic core of which includes the telomerase reverse transcriptase (TERT) and the non-codi

203 mally consisting of a protein subunit called telomerase reverse transcriptase (TERT) and the telomera

204 ic mutations in the promoter of the gene for telomerase reverse transcriptase (TERT) are the most com

205 telomerase complex is influenced more by the telomerase reverse transcriptase (TERT) binding of the C

206 ls immortalized by the ectopic expression of telomerase reverse transcriptase (TERT) can give rise to

207 nt insights to the noncanonical functions of telomerase reverse transcriptase (TERT) catalytic subuni

208 ve suggested that the core protein mammalian telomerase reverse transcriptase (TERT) component, toget

209 Telomerase reverse transcriptase (TERT) confers the cata

210 Differential regulation of telomerase reverse transcriptase (TERT) contributes to t

211 To perform DNA synthesis, the active site of telomerase reverse transcriptase (TERT) copies a templat

212 omerase RNA template, the active site in the telomerase reverse transcriptase (TERT) core, a TERT N-t

213 lete single-repeat synthesis requires only a telomerase reverse transcriptase (TERT) core.

214 in lung fibrosis, we examined the effects of telomerase reverse transcriptase (TERT) deficiency in a

215 the overexpression of myocardin (MYOCD) and telomerase reverse transcriptase (TERT) enhanced the sur

216 Reactivation of telomerase reverse transcriptase (TERT) expression enabl

217 Reactivation of telomerase reverse transcriptase (TERT) expression is fo

218 been previously shown that expression of the telomerase reverse transcriptase (TERT) gene extends the

219 ating mutations occur in the promoter of the telomerase reverse transcriptase (TERT) gene in 66% of m

220 , and point mutations in the promoter of the telomerase reverse transcriptase (TERT) gene increase te

221 ure in MYCN nonamplified neuroblastomas with telomerase reverse transcriptase (TERT) gene overexpress

222 is of B-cell lymphoma DNA confirmed that the telomerase reverse transcriptase (TERT) gene promoter is

223 Point mutations in the telomerase reverse transcriptase (TERT) gene promoter oc

224 risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (TERT) gene that encode

225 find a germline deletion in intron 3 of the telomerase reverse transcriptase (TERT) gene that predis

226 tudy, the role of Smad3 in the inhibition of telomerase reverse transcriptase (TERT) gene transcripti

227 ty is characterized by the expression of the telomerase reverse transcriptase (TERT) gene, suggesting

228 Differential regulation of telomerase reverse transcriptase (TERT) genes contribute

229 ed variants of human telomerase RNA (hTR) or telomerase reverse transcriptase (TERT) have exploited i

230 his study, we extend these observations into telomerase reverse transcriptase (TERT) immortalized ora

231 somatic acquisition of promoter mutations in telomerase reverse transcriptase (TERT) in blood leukocy

232 mplate boundary definition and high affinity telomerase reverse transcriptase (TERT) interaction.

233 Telomerase reverse transcriptase (TERT) is an essential

234 Because telomerase reverse transcriptase (TERT) is usually the l

235 Similarly, telomerase reverse transcriptase (tert) mutant zebrafish

236 ue activity in the catalytic protein subunit telomerase reverse transcriptase (TERT) of telomerase.

237 e downstream network in mice null for either telomerase reverse transcriptase (Tert) or telomerase RN

238 arrow carrying heterozygous mutations in the telomerase reverse transcriptase (TERT) or the telomeras

239 nations of defined tumor-expressed antigens, telomerase reverse transcriptase (TERT) or TRP-2, and VE

240 ct somatic single-nucleotide variants in the telomerase reverse transcriptase (TERT) promoter and iso

241 Mutations in the human telomerase reverse transcriptase (TERT) promoter are the

242 We aimed to evaluate the occurrence of telomerase reverse transcriptase (TERT) promoter mutatio

243 The telomerase reverse transcriptase (TERT) promoter, an imp

244 Integrations in the telomerase reverse transcriptase (TERT) promoter/enhance

245 genes, including MYC transactivation of the telomerase reverse transcriptase (TERT) promoter; and in

246 somes and consists of two main subunits: the telomerase reverse transcriptase (TERT) protein and an a

247 daka and fugu TRs, when assembled with their telomerase reverse transcriptase (TERT) protein counterp

248 ue TR-binding domain (TRBD) in the catalytic telomerase reverse transcriptase (TERT) protein, integra

249 teraction between the CR4-CR5 domain and the telomerase reverse transcriptase (TERT) protein.

250 Transcriptional reactivation of telomerase reverse transcriptase (TERT) reconstitutes te

251 of telomerase-associated proteins other than telomerase reverse transcriptase (TERT) remain ambiguous

252 Here, using telomerase reverse transcriptase (Tert) reporter mice, w

253 activity by repressing the catalytic subunit telomerase reverse transcriptase (TERT) through negative

254 determined structures of Tribolium castaneum telomerase reverse transcriptase (TERT) throughout its c

255 e that facilitates the subsequent binding of telomerase reverse transcriptase (TERT) to TER.

256 ize telomeric repeats, the catalytic subunit telomerase reverse transcriptase (TERT) uses the RNA sub

257 novel alternatively spliced (AS) variants of telomerase reverse transcriptase (TERT) were identified,

258 ver, tumorigenesis-associated genes IGF2 and telomerase reverse transcriptase (TERT) were overexpress

259 vitro with only the telomerase RNA (hTR) and telomerase reverse transcriptase (TERT), additional comp

260 -occurrence of mutations in the promoter for telomerase reverse transcriptase (TERT), along with BRAF

261 on of the catalytic component of telomerase, telomerase reverse transcriptase (TERT), alters sensitiv

262 s a ternary complex of telomerase RNA (TER), telomerase reverse transcriptase (TERT), and the essenti

263 ase RNA and a catalytic protein subunit, the telomerase reverse transcriptase (TERT), as well as seve

264 to mutations in the same genes, such as the telomerase reverse transcriptase (TERT), but through dif

265 RNA (TR) or the catalytic protein component telomerase reverse transcriptase (TERT), cause the genet

266 Regulator of telomere length-1 (RTEL1) and telomerase reverse transcriptase (TERT), genes involved

267 P. tetraurelia telomerase catalytic subunit, telomerase reverse transcriptase (TERT), has been cloned

268 s required for telomere maintenance, such as telomerase reverse transcriptase (TERT), have been found

269 Remarkably, with only binding sites for telomerase reverse transcriptase (TERT), minimized hTR a

270 ically organized by the components, i.e. the telomerase reverse transcriptase (TERT), telomerase RNA

271 often determined by the expression level of telomerase reverse transcriptase (TERT), the catalytic s

272 s exhibiting dysregulated growth may express telomerase reverse transcriptase (TERT), the dual functi

273 endent mutations within the core promoter of telomerase reverse transcriptase (TERT), the gene coding

274 omponents have been identified thus far: the telomerase reverse transcriptase (TERT), the telomerase

275 g an internal RNA template and a specialized telomerase reverse transcriptase (TERT), thereby maintai

276 on of the catalytic component of telomerase, telomerase reverse transcriptase (Tert), which is essent

277 Among 6,835 cancers, 73% expressed telomerase reverse transcriptase (TERT), which was assoc

278 riven by the transcriptional upregulation of telomerase reverse transcriptase (TERT).

279 onents, the telomerase RNA template (TR) and telomerase reverse transcriptase (TERT).

280 s using an integral telomerase RNA (TER) and telomerase reverse transcriptase (TERT).

281 , using an integral telomerase RNA (TER) and telomerase reverse transcriptase (TERT).

282 Cancer cells depend on transcription of telomerase reverse transcriptase (TERT).

283 chanistically, ASA treatment upregulates the telomerase reverse transcriptase (TERT)/Wnt/beta-catenin

284 an stem and cancer cells express telomerase [telomerase reverse transcriptase (TERT)] in an effort to

285 Furthermore, an evident up-regulation of telomerase reverse-transcriptase (TERT) expression was d

286 ted the expression of the catalytic subunit (telomerase reverse transcriptase [TERT]) but had no effe

287 ted RNA subunit and a reverse transcriptase (telomerase reverse transcriptase [TERT]).

288 , called motif 3, in the catalytic domain of telomerase reverse transcriptase, that is crucial for te

289 east three principal subunits, including the telomerase reverse transcriptase, the telomerase RNA (TE

290 alter the overall stability or expression of telomerase reverse transcriptase, these rare genetic dis

291 NA, which in turn directs the binding of the telomerase reverse transcriptase to form the functional

292 Telomerase reverse transcriptase (TRT) is a tumor-associ

293 ked with a homology model of the Tetrahymena telomerase reverse transcriptase (tTERT) to characterize

294 sing tissue reconstruction techniques; human telomerase reverse transcriptase was required for cells

295 The catalytic subunit, telomerase reverse transcriptase, was expressed in human

296 ficient mutations in TERT, the gene encoding telomerase reverse transcriptase, we asked whether resto

297 xpressed c-kit, interleukin-31 receptor, and telomerase reverse transcriptase when compared with cont

298 Furthermore, recombinant AREG induced telomerase reverse transcriptase, which appeared to be e

299 amplicon and also encompasses TERT, encoding telomerase reverse transcriptase, which plays a critical

300 TERT encodes telomerase reverse transcriptase, which together with th