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1 e of the protein that differentially mediate telomere function.
2 inding complex implicated in both aspects of telomere function.
3  binding as an efficient means of disrupting telomere function.
4 st testable models for the roles of TERRA in telomere function.
5  best known for their role in maintenance of telomere function.
6 processes such as genomic translocations and telomere function.
7 e effects of affinity from repeat spacing on telomere function.
8 their inhibitory effect on telomerase and/or telomere function.
9 omeric DNA are thought to play a role in the telomere function.
10 protein, DNA, and RNA molecules required for telomere function.
11 omeric DNA and regulates numerous aspects of telomere function.
12              Length regulation is central to telomere function.
13 ase or recombination is utilized to maintain telomere function.
14 ion of HHV-6A or 19q genes or else disrupted telomere function.
15 protein Rap1p is thought to be essential for telomere function.
16  when DNA lesions are created by the loss of telomere function.
17 hing an essential role for these proteins in telomere function.
18 change, studies that will shed more light on telomere function.
19  catalytic activity was proposed to regulate telomere function.
20 tside this range are associated with altered telomere function.
21 taining the cap complex essential for normal telomere function.
22                    DNA methylation modulates telomere function.
23 s, including transcription, replication, and telomere function.
24 nescence via SSB intermediates which disrupt telomere function.
25 e subtelomere perturb subtelomere-dependent, telomere functions.
26 ma-specific pathways involved in mitotic and telomere functions.
27 be are bound by Taz1, a regulator of diverse telomere functions.
28 ranscriptional activation, and silencing and telomere functions.
29 and several molecular mechanisms involved in telomere functions.
30 ent function of Nmd2p/Rlf4p, is required for telomere functions.
31 els of specific mRNAs that are important for telomere functions.
32 l telomeres restored telomerase activity and telomere function, alleviated cirrhotic pathology, and i
33 entified in a screen for mutants that affect telomere function and alter the localization of the telo
34 either positive or negative contributions to telomere function and cell viability, depending on wheth
35  Exo1 activity was also capable of enhancing telomere function and consequently cell proliferation, b
36  review, we describe the impact of ncRNAs on telomere function and discuss their implications in sene
37 omplex formation between hRap1 and hTRF2 for telomere function and end protection.
38 oining of telomeric DNA, can lead to loss of telomere function and genomic instability.
39 n contrast, reducing miR-155 levels improved telomere function and genomic stability.
40           Telomere integrity is critical for telomere function and genomic stability.
41 lomere length is an important determinant of telomere function and has a strong genetic basis.
42 ty and processivity are required to maintain telomere function and immortalize human cells with limit
43         Reactivation of telomerase maintains telomere function and is considered critical to immortal
44  individuals, are critical for understanding telomere function and its roles in human biology.
45 dings suggest variation in genes relevant to telomere function and maintenance may be important in th
46 ciated with mutations in genes involved with telomere function and maintenance; however, the genetic
47                 Correspondingly, the loss of telomere function and p53 deficiency cooperated to initi
48 f HSCs, thereby preventing premature loss of telomere function and providing added replicative capaci
49 rocomplex are known to participate in native telomere functions and also regulate the de novo telomer
50 ex structures are believed to play a role in telomere functions and considered as targets for antican
51                                   Changes in telomere functions and the associated chromosomal abnorm
52 omatin is critical for proper centromere and telomere function, and it plays a key role in the transc
53 mmary tumors is not linked to global loss of telomere function but involves multiple regulatory event
54 fission yeast Taz1 protein regulates diverse telomere functions but is not essential for growth under
55 ing the direct modulation of cell telomerase/telomere function by an oncogenic virus and suggest its
56                       Rap1 could orchestrate telomere function by binding multiple telomere array sit
57                                      Loss of telomere function can induce cell cycle arrest and apopt
58         Regardless of the mechanism, loss of telomere function can result in sister chromatid fusion
59                                  The loss of telomere function can result in the fusion of telomeres
60                                      Loss of telomere function causes cell-cycle arrest or cell death
61  these nucleotides on telomerase activity or telomere function could contribute to the mechanism of a
62                               Paradoxically, telomere function depends on checkpoint proteins such as
63                                      Loss of telomere function did not elicit a full spectrum of clas
64 g against a role for the nuclear envelope in telomere function during interphase.
65 however, the importance of these factors for telomere function has not been understood.
66 ults described here demonstrate that loss of telomere function in a cancer-prone mouse model possessi
67 leomycin, underscoring an essential role for telomere function in AEC2s for alveolar repair.
68 d to telomeric DNA in vitro, suggesting that telomere function in human cells is regulated by poly(AD
69                                      Loss of telomere function in metazoans results in catastrophic d
70  will allow a more complete understanding of telomere function in the cell.
71 ms of telomeric DNA interaction in vitro and telomere function in vivo.
72 hanism(s) by which recombination can restore telomere function in yeast, and suggest future experimen
73                                              Telomere functions in somatic cells involve complexes be
74 and SIR4, genes which influence a variety of telomere functions in yeast, also had no effect.
75 nd neck (SCCHN), need telomerase to maintain telomere function; inhibition of the enzyme can lead to
76                                      Loss of telomere function is an important mechanism for the chro
77                                      Loss of telomere function is associated with rampant genetic ins
78                                         When telomere function is disrupted, a potentially lethal DNA
79 somal abnormalities in the absence of proper telomere function is implicated in human aging and cance
80 etabolism and will provide insights into how telomere function is linked to many other cellular proce
81                                        Human telomere function is mediated by shelterin, a six-subuni
82 lication, providing additional evidence that telomere function is sequence-specific.
83 irement of heterochromatin proteins for most telomere functions is unknown.
84 s review we consider whether manipulation of telomere function may selectively sensitise SCCHN to rad
85  a variety of biological processes including telomere function, meiotic recombination and gene regula
86 otyping (SKY) analysis revealed that loss of telomere function occurred preferentially on chromosomes
87                           Examination of the telomere functions of Rap1 is complicated by the fact th
88 (Terc), to assess the role of telomerase and telomere function on the cellular and organismal respons
89  that influence either telomere structure or telomere function (or both), although in many cases the
90                      Molecular mechanisms of telomere functions remain unknown in large part due to l
91 ) is a multifunctional protein that controls telomere function, silencing and the activation of glyco
92 ction has a clinically significant impact on telomere function, suggesting the existence of "telo-miR
93        Strikingly, in cells with compromised telomere function (taz1Delta), SpEst1p loss confers a le
94           In the present study, an essential telomere function, the ability to cap and thereby protec
95                                  Compromised telomere function then spurs adaptation of telomere prot
96 t of chromosome segregation and that loss of telomere function through progressive telomere shortenin
97  component of telomerase, serves to maintain telomere function through the de novo addition of telome
98 t the GCN5-containing SAGA complex regulates telomere function via deubiquitination and stabilization
99 le of ataxia-telangiectasia mutated (Atm) in telomere function, we generated Atm and telomerase null
100 o determine how the TIN2-DC mutations affect telomere function, we generated mice with the equivalent
101         Using a screen for genes that affect telomere function, we isolated sir3-P898R, an allele of

 
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