ライフサイエンスコーパス: terbium

1 were known only for cerium and more recently terbium.

2 al probing method using the lanthanide metal terbium.

3 Terbium-149g ([Formula: see text] = 4.12 h) is of partic

4 Terbium-155 prepared by proton irradiation and on-line m

5 Experiments using terbium, a fluorescent calcium analogue, confirm the spe

6 Terbium, a lanthanide ion, blocked motility even when ca

7 hate interference 1000-fold compared to free terbium alone.

8 eded 14 tesla below 50 and 60 kelvin for the terbium and dysprosium compounds, respectively.

9 The Bi(2)(3-) radical-bridged terbium and dysprosium congeners, 2-Tb and 2-Dy, are sin

10 lmium as a supplement and/or replacement for terbium and dysprosium, suggesting shifting industrial t

11 UV excitation required to sensitize discrete terbium and europium complexes can be overcome using Che

12 Terbium and nitrogen co-doped carbon dots (Tb@N-CDs), co

13 trypsin; loss of time-gated FRET between the terbium and QD signaled the activity of trypsin.

14 ubstrate shows a high degree of FRET between terbium and YFP, whereas DUB-dependent cleavage leads to

15 The properties of the gadolinium, terbium, and dysprosium complexes of these ligands were

16 his TnT isoform was first investigated using terbium as a calcium analogue due to its more readily de

17 encoded lanthanide-binding tag (LBT) to bind terbium as a LRET donor and a fluorophore-labeled iberio

18 s also accessible in a molecular compound of terbium as demonstrated by oxidation of the tetrakis(sil

19 xcited currents generated from an iron and a terbium atom coordinated to organic ligands are detected

20 A terbium-based complex that displays a water exchange CES

21 strophin monoclonal antibody conjugated to a terbium-based resonance energy transfer donor and anti-a

22 Thus, a strategy of using terbium-based TR-FRET can be applied to develop kinase a

23 Using this three-channel terbium-based, TR-FRET assay system, we show in one expe

24 In an intact probe, the average terbium-BHQ distance is short, and Tb --> BHQ energy tra

25 terbium/BHQ probes is very dependent on the terbium-BHQ distance.

26 Luminescence quenching efficiency within terbium/BHQ probes is very dependent on the terbium-BHQ

27 Terbium binding and isothermal titration calorimetry dat

28 nds 4 mol of calcium/mol of protein and that terbium-binding stoichiometry is similar to that of calc

29 fluorescence overlaid on a much longer lived terbium-centered component.

30 unprocessed serum, by taking advantage of a terbium chelate complex with long luminescence lifetime

31 After a brief excitation pulse, terbium chelates emit for milliseconds after the intrins

32 ntage of the long phosphorescent lifetime of terbium chelates, a property that enables the accurate d

33 iC stem minihelix, as evidenced by increased terbium cleavage in this domain.

34 At low concentrations of NC, the strong terbium cleavage observed in the core region of the tRNA

35 ntroduced into P4 cause local changes in the terbium cleavage pattern due to alternate metal ion-bind

36 In light of the alternate terbium cleavage pattern in P4 caused by bulge deletion,

37 nformation at low Mg(2+) concentrations, and terbium-cleavage assays suggest that this increase is du

38 The resulting terbium coiled coil displays luminescent properties cons

39 Terbium complex (Tb)-labeled hexahistidine-tagged nanobo

40 onstituents of the FRET relay, a luminescent terbium complex and fluorescent dye, were assembled to Q

41 LRET between the eDHFR-bound terbium complex and green fluorescent protein (GFP) was

42 A stable and highly luminescent terbium complex based on a tetraisophthalamide (TIAM) ch

43 he four luminescent lanthanides studied, the terbium complex exhibits the greatest dipicolinate bindi

44 ied with the aid of the W220Y mutant and the terbium complex of the apoenzyme.

45 s to reversal of the magnetization, and a di-terbium complex that displays magnetic hysteresis up to

46 S(4) symmetric, four-coordinate tetravalent terbium complex, [Tb(NP(1,2-bis-(t)Bu-diamidoethane)(NEt

47 A luminescent terbium complex, TMP-Lumi4, was introduced into cultured

48 residues were employed to anchor luminescent terbium complexes and biotin groups based on orthogonal

49 Luminescent terbium complexes are an example of such a material, and

50 of the particle, as an energy acceptor, and terbium complexes as an energy donor.

51 ss large energy barriers, and dysprosium and terbium complexes bridged by an N2(3-) radical ligand ex

52 While terbium complexes were used as luminescent signaling gro

53 d to a number of different proteins, and the terbium complexes' exceptional photophysical properties

54 of CoraFluors, a new class of macrotricyclic terbium complexes, which are synthetically readily acces

55 of single-molecule-magnet behavior, with the terbium congener exhibiting magnetic hysteresis at 14 K

56 re linked to metal ion interactions, we used terbium-dependent cleavage of the phosphate backbone to

57 Our calculations also show that terbium dioxide has a high electronic entropy and thus c

58 cium dipicolinate to form highly luminescent terbium dipicolinate complexes surrounding each germinat

59 Moreover, TprC(Fl) increased efflux of terbium-dipicolinic acid complex from large unilamellar

60 Using terbium-dipicolinic acid complex-loaded large unilamella

61 ituted lanmodulin can quantify 3 ppb (18 nM) terbium directly in acid mine drainage at pH 3.2 in the

62 the three acceptors at the four channels for terbium donor emission, we demonstrate that any of these

63 organic acceptor fluorophores paired with a terbium donor fluorophore, we have developed the first e

64 uorescent protein (GFP) can be paired with a terbium donor in a TR-FRET assay, we have developed TR-F

65 cent protein (YFP) and a chemically attached terbium donor.

66 magnitude of the three FRET signals in this terbium-donor triple-acceptor system with minimal bleedt

67 resonance energy transfer (TG-FRET) between terbium donors and dye acceptors into HCR for multiplexe

68 rth elements (yttrium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium

69 is lanthanum, cerium, samarium, gadolinium, terbium, dysprosium, thulium, or calcium.

70 raacetic acid) based on a highly fluorescent terbium-EDTA-salicylic acid complex formation was develo

71 y transfer is efficient, decreasing both the terbium emission intensity and lifetime.

72 hree repeats using changes in tryptophan and terbium fluorescence and perturbation of [1H-15N]-HSQC N

73 ophan fluorescence and tryptophan-sensitized terbium fluorescence indicate that the calcium binding s

74 T assays involve a TRE sequence labeled with terbium (fluorescence donor), TRbeta.RXRalpha heterodime

75 n adsorption activity of 6.01 +/- 0.11 mumol-terbium/g-sorbent and fast adsorption kinetics.

76 constraints are likely to occur for gallium, terbium, germanium, tellurium, indium, uranium and coppe

77 Since terbium has been used extensively as a probe for the det

78 Coordinated lanthanide ions, such as terbium (III) (Tb(3+)), can also be recruited to these s

79 the basis of enhancement of the emission of terbium (III) ions.

80 luorescence emission of the lanthanide metal terbium(III) (Tb(3+)) when it interacts with the aromati

81 Terbium(III) [Tb(III)] was shown to inhibit the hammerhe

82 s regard by using lanthanide centres such as terbium(III) and dysprosium(III), whose anisotropy can l

83 apable of quantitative TG imaging of PL from terbium(III) and europium(III) LLCs, including rejection

84 acetic acid coupled with the luminescence of terbium(III) as the basis for a continuous assay of este

85 trated by oxidation of the tetrakis(siloxide)terbium(III) ate complex, [KTb(OSi(O (t)Bu)(3))(4)], 1-T

86 ecursor and product we observe high-affinity terbium(III) binding sites in joining sequence J4/2 (Tb(

87 eled with either a long lifetime luminescent terbium(III) complex (Tb) or a fluorescent dye, Alexa Fl

88 otors, based on the sensitized emission of a terbium(III) complex.

89 We show, using terbium(III) footprinting and sensitized luminescence sp

90 Terbium(III) footprinting detects conformations for the

91 d subtle, yet significant differences in the terbium(III) footprinting pattern between the precursor

92 uorescence spectroscopy, circular dichroism, terbium(III) footprinting, and X-ray crystallography of

93 rosine kinase-inducible domain peptides bind terbium(III) in a phosphorylation-dependent manner, show

94 Here, we have used the lanthanide metal ion terbium(III) to footprint the precursor and product solu

95 Here, we augment these studies by using terbium(III) to probe the structure of the trans-acting

96 ynergizing the strong magnetic anisotropy of terbium(III) with the effective exchange-coupling abilit

97 aqueous complex of the lanthanide metal ion terbium(III), Tb(OH)(aq)(2+), reversibly inhibit the rib

98 nosalicylic acid ethylenediaminetetraacetate terbium(III), were evaluated for the analysis of carboni

99 Conversion of terbium into a form suitable for chelation to targeting

100 Terbium ion (Tb3+), a fluorescent trivalent cation that

101 e, as revealed by sensitivity to cleavage by terbium ion and by the ability of the internal loop to d

102 ufficiently covalent so that the tetravalent terbium ion is stable and accessible via a mild oxidant

103 combined the favorable characteristics of a terbium-ion-containing lanthanide-binding peptide (Tb(3+

104 ranes coupled with anomalous scattering from terbium ions (Tb3+) titrated into presumed Ca2+ binding

105 de-alkyne cycloaddition, covalently attached terbium ions to prenylated proteins within cells.

106 Studies of hypothetical praseodymium(IV) and terbium(IV) analogues suggest the inverse-trans-influenc

107 d such that each myosin molecule contained a terbium-labeled (luminescent donor) RLC on one head and

108 gged ERRgamma ligand-binding domain (LBD), a terbium-labeled anti-GST antibody, a fluorescein-labeled

109 ion or phosphorylation using a unique set of terbium-labeled antibodies in a time-resolved Forster re

110 an increase in TR-FRET when incubated with a terbium-labeled antibody that specifically recognizes th

111 estrogen from the ligand binding pocket of a terbium-labeled estrogen receptor, at the same time caus

112 rt a powerful alternative (GlycoFRET), where terbium-labeled fluorescent reporters are irreversibly a

113 rresponding to a final concentration of 6 pM terbium-labeled probes detectable by ICP-MS after elutio

114 kinase assays, and the unique properties of terbium lead to a high degree of flexibility with regard

115 onal cation binding site as assessed by both terbium luminescence and electrospray ionization mass sp

116 adhesion site (MIDAS) motif, was assessed by terbium luminescence to evaluate conformational perturba

117 Here, we use sensitized terbium luminescence to probe the mechanism of lanthanid

118 um luminescence when phosphorylated but weak terbium luminescence when not phosphorylated.

119 phorylation-dependent manner, showing strong terbium luminescence when phosphorylated but weak terbiu

120 inity as demonstrated by tryptophan-enhanced terbium luminescence.

121 phatase YOP resulted in a large reduction in terbium luminescence.

122 h Abl kinase resulted in a large increase in terbium luminescence.

123 Full-length calbindin D28K bound 4 mol of terbium/mol of protein, while calbindin delta2 and delta

124 Terbium offers 4 clinically interesting radioisotopes wi

125 Since terbium often substitutes at calcium-binding sites, radi

126 Reduction of iodide-bridged terbium or dysprosium dimers resulted in a single electr

127 l usefulness of the combined use of laccase, terbium oxide nanoparticles (Tb4O7NPs) and 8-hydroxypyre

128 tic study of the formation of europium-doped terbium phosphate nanocrystals under acidic conditions,

129 e-molecule magnets: recent studies show that terbium phthalocyanine complexes possess large energy ba

130 a mild oxidant from the anionic, trivalent, terbium precursor, [(Et(2)O)K][Tb(NP(1,2-bis-(t)Bu-diami

131 opy with a selectively targeted, luminescent terbium protein label affords improved speed and sensiti

132 Four terbium radioisotopes ((149, 152, 155, 161)Tb) constitut

133 proof-of-concept study was to produce all 4 terbium radioisotopes and assess their diagnostic and th

134 Carrier-free terbium radioisotopes were obtained after purification,

135 greater than 96% radiochemical yield for all terbium radioisotopes.

136 For the first time, to our knowledge, 4 terbium radionuclides have been tested in parallel with

137 Treatment with a terbium reporter containing an azide functional group, f

138 M(4,5) absorption edge signals for iron and terbium, respectively, are clearly observed in the X-ray

139 -Tb separation of 3.9020(10) A for the major terbium sites.

140 tion by this protein as well as to develop a terbium-specific biosensor that can be applied directly

141 ffect of lanthanide cofactors, in particular terbium (Tb(3+)), for DNA-catalyzed synthesis of 2',5'-b

142 content along with another REE, particularly terbium (Tb).

143 We have employed 45CaCl2 binding studies, terbium (Tb3+) luminescence spectroscopy, and electrospr

144 ly complex lanthanide ions and can sensitize terbium (Tb3+) luminescence.

145 sphate (PPi) amplifies the green emission of terbium through bridging coordination by inducing carbon

146 mission by deactivating the excited state of terbium through energy transfer.

147 ng proteins, we also examined the binding of terbium to the three proteins under the same conditions.

148 Here, a bright and photostable terbium-to-quantum dot (QD) Forster resonance energy tra

149 c acid did not form fluorescent complex with terbium under the same conditions.

150 Using the fluorescent calcium analog terbium, we found that heparinase I tightly bound divale

151 and TnT N-terminal fragment (TnT N47) bound terbium with high affinity indicating that the N-termina

152 All five mutants bound terbium with unaltered affinities.