ライフサイエンスコーパス: terminal region

1 ivo through direct recognition of the MinD N-terminal region.

2 he sequence differences are located in the N-terminal region.

3 abilize the alpha-helical character of the C-terminal region.

4 hose of peptides corresponding to the CCR1 N-terminal region.

5 membrane protein beta-dystroglycan via its C-terminal region.

6 ng cytochrome domain is fused to the AfGDH N-terminal region.

7 ributable to conformational changes in the N-terminal region.

8 e orientation of the helices (alpha1-3) in N-terminal region.

9 m the presence of an acidic residue at its N-terminal region.

10 etrating cation-dependent mechanism in its N-terminal region.

11 nt segment (positions 61-67) in the FLIL33 N-terminal region.

12 cting on different receptors within the same terminal region.

13 emely transient helices are present in the N-terminal region.

14 function for other amino acids within this C-terminal region.

15 -binding sequence (CBS) located within its C-terminal region.

16 conserved cysteine residues located in the C-terminal region.

17 g oligomerization involving binding to the C-terminal region.

18 a large N-terminal domain and a catalytic C-terminal region.

19 N-terminal disease-related surface, and a C-terminal region.

20 M domain with a more flexible and extended C-terminal region.

21 of the highly charged and flexible carboxyl-terminal region.

22 nt-Sim (PAS) domain in their intracellular N-terminal region.

23 inal lysine residues but not at central or C-terminal regions.

24 ystallin domain flanked by variable N- and C-terminal regions.

25 ENP-A targeting domain and either one of its terminal regions.

26 e-binding domains were mapped within their N-terminal regions.

27 yotic replisome, Timeless, harbours in its C-terminal region a previously unappreciated DNA-binding d

28 fold has no impact on oligomerization, but N-terminal regions affect the dimer-tetramer equilibrium i

29 roteins from chromatin, bound to the Stat3 C-terminal region and antagonized its transcriptional and

30 , has a CaM-binding peptide located in its N-terminal region and displays peculiar biochemical proper

31 This alpha-helix was located in the C-terminal region and included residues 101-106.

32 Effects on alpha6beta4 involve BARP's N-terminal region and IRE1alpha's splicing of XBP1 mRNA.

33 ry for +TIP activity whereas the conserved C-terminal region and its PGGG motif are not.

34 kine N-loop/beta3 region to the receptor's N-terminal region and subsequent insertion of the chemokin

35 form higher-order oligomers through their N-terminal region and that the same AT-rich site is recogn

36 ng of the [4Fe-4S] cluster by the flexible N-terminal region and the associated inhibition of the act

37 Here we report that the Set1 N-terminal region and the COMPASS subunit Swd2, which inte

38 cation of the WWP2 isoforms containing the N-terminal region and their interaction with SMAD2.

39 hanges that affect the solvent exposure of N-terminal region, and hence the redox sensitivity of the

40 f PINK1, including the architecture of the C-terminal region, and reveals how the N lobe of PINK1 bin

41 a newly defined ILT7-binding surface, the N-terminal region appears to suppress ILT7 activation.

42 ng truncated MeCP2 lacking both the N- and C-terminal regions (approximately half of the native prote

43 c assemblies in which interactions between N-terminal regions are important.

44 We further show that the terminal regions are required for stable fibril binding

45 ues within the core LIR motif and adjacent C-terminal region as well as ATG8 subfamily-specific resid

46 of UPF1 occurs in its unstructured N- and C-terminal regions at Serine/Threonine-Glutamine (SQ) moti

47 Moreover, its amino-terminal region binds FLASH, an RDH-specific 3'-end proc

48 Kindlin-2, through its C-terminal region, binds to and stabilizes MafA, which act

49 structure and dynamics of the p150(Glued) N-terminal region, both free and in complex with polymeriz

50 activation required not only the conserved N-terminal region but also permissive communication of the

51 However, phosphorylation at the GarA N-terminal region by the protein kinase PknB or PknG trigg

52 at serine phosphorylation within the ICAP1 N-terminal region can prevent nuclear ICAP1 accumulation,

53 diA effector proteins, which carry a toxic C-terminal region (CdiA-CT) that is cleaved from the effec

54 n homology (PH) domains interacts with the N-terminal region comprising ARL8- and kinesin-1-binding s

55 lographic structure of the Arabidopsis TPL N-terminal region comprising the LisH and CTLH (C-terminal

56 -function analyses of SKIP reveal that the C-terminal region comprising three pleckstrin homology (PH

57 missense mutations in the RING domain and N-terminal region compromise its activity, and therefore p

58 We find that the N- and C-terminal regions constitute two independent domains of S

59 r DNA binding and, in combination with the N terminal region, constitute a functional transactivator.

60 angiosperms and possess a highly conserved C-terminal region containing linear motifs (CKII-acidic, L

61 th a C-terminal RING domain and disordered N-terminal region containing SUMO Interactions Motifs (SIM

62 a C-terminal helical bundle and a dynamic N-terminal region containing two disulfide linkages.

63 Further, the Rgd3 C-terminal region contains several phosphorylatable residu

64 The C-terminal region contains the catalytic glucosyltransfera

65 The results revealed that the chemokine N-terminal region contributes significantly to binding aff

66 MBS (localized within and adjacent to the C-terminal region) contributing to the dimer-dimer interac

67 ed splice-site mutation that truncates the C-terminal region (CTR) domain of RELN protein and display

68 326-380 of p62 directly interact with the C-terminal region (CTR) of FIP200.

69 The IB2 gene (chr22q13.3 terminal region) deletion occurs in virtually all cases

70 over, deletions at both ends of the N- and C-terminal regions disrupt their ability to interact with

71 We further show that the N- and C-terminal regions, either separated or when fused in tand

72 We recently proposed that the C-terminal region encompassing the C(1), C(2)B, MUN and C(

73 ctivate ILT7, whereas substitutions in its N-terminal region enhance activation.

74 protective subdominant responses to PfCSP C-terminal regions expanded with subsequent boosts.

75 n intrinsically disordered, low-complexity N-terminal region flanking the coil-coiled self-associatio

76 ies are indirectly regulated by the N- and C-terminal regions flanking the FH1-FH2 domains.

77 The N-terminal region formed a solvent-exposed patch located o

78 n TRP structures, together with the carboxyl-terminal region, forms a large two-layered cytosolic rin

79 We demonstrate here that a yeast-specific C-terminal region from Pat1 interacts with several short m

80 nt the crystal structures of the catalytic C-terminal regions from the Burkholderia pseudomallei and

81 ssive C-terminal deletions showed that the C-terminal region has higher affinity for ssDNA than the N

82 ase and methyltransferase (MTase), and the C-terminal region has the polymerase (POL), all of which a

83 ith deletion of residues 338 to 347 in the C-terminal region, has been an enigma, because the basis f

84 opy assays indicated that the Rec10 N- and C-terminal regions have complex interactions with Rec25.

85 osphorylation sites and truncations of the N-terminal region highlighted reduced lipid accumulation c

86 ous Glu-to-Lys substitutions in alphaSyn's N-terminal region (i.e. E35K and E61K).

87 ing and mass spectrometry, we identified a C-terminal region in Hel2/Rqt1 as an RNA binding domain.

88 LDL binding in vitro requires a disordered N-terminal region in PCSK9's prodomain.

89 at both mutations lead to unfolding of the C-terminal region in the t-SNARE complex.

90 Btl) proteins bind DNA but lack the N- and C-terminal regions, in which TAL effectors harbor their T3

91 the interaction between AP2M and the TRKB C-terminal region, indicating that the fluoxetine-binding

92 to a lesser extent at Ser-25, within this N-terminal region inhibit ICAP1 nuclear accumulation.

93 reas phosphorylation in the N-terminal and C-terminal regions inhibited but did not prevent fibrillat

94 th peptides corresponding to the conserved C-terminal region inhibits the extracellular assembly of M

95 and subsequent insertion of the chemokine N-terminal region into the transmembrane helical bundle of

96 Cross-dimer domain-swapping of the C-terminal region is a determinant of alphaA-crystallin he

97 The largely disordered/dynamic C-terminal region is conjectured to mediate the promiscuou

98 N-terminal transmembrane domain, while the C-terminal region is cytosolic.

99 al to what is observed when the entire LIC C-terminal region is deleted.

100 kinase-mediated phosphorylation within the C-terminal region is inhibitory and regulates catalytic ac

101 mplex is CcmM, a multidomain protein whose C-terminal region is required for RubisCO recruitment.

102 ntial for its biological function, and its C-terminal region is sufficient for LLG binding.

103 The MDM2 amino-terminal region is sufficient to bind NDUFS1, alter supe

104 and demonstrate that perturbations of the C-terminal region lead to developmental defects in both hu

105 hannel that otherwise binds ppGpp, and its N-terminal region, like the coiled-coil tip of DksA, engag

106 er RALF peptides that share this conserved N-terminal region may be perceived by LLG proteins in a si

107 against hydrogen/deuterium exchange in the C-terminal region near the N-glycan sites, suggesting this

108 al or bacterial GEs, with a large inserted N-terminal region neighboring the active site and a differ

109 Although the N-terminal region normally localizes to podocyte foot proc

110 to sites within the enigmatic, disordered N-terminal region (NTR) of HspB1.

111 In the human sHSP HSPB1, the disordered N-terminal region (NTR) represents nearly 50% of the seque

112 spliced isoforms, differing only in their N-terminal regions (NTRs).

113 igated metal ions bind specifically to the N-terminal region of Abeta, forming a dynamic, partially c

114 ely inhibited by antibodies binding to the C-terminal region of Abeta42.

115 vely inhibited by antibodies targeting the N-terminal region of Abeta42.

116 sing biochemical assays, we found that the N-terminal region of AKAP8L binds to mTORC1 in the cytopla

117 rdomain region (CIDR) domains found in the N-terminal region of all PfEMP1.

118 Glycation affected primarily the N-terminal region of alpha-synuclein, reducing membrane bi

119 is a rare example of a replacement in the N-terminal region of amylin.

120 Thus, an NH2-terminal region of approximately 30 amino acids of Swi1

121 us studies suggested the importance of the C-terminal region of B-chain in this pathway.

122 Cross-linking between the C-terminal region of both E1a and G729R E1a with the E2o l

123 The very C-terminal region of Bruchpilot (Brp), a key component of

124 nd-like Ca(2+) binding motif in the carboxyl terminal region of BTV nonstructural phosphoprotein 2 (N

125 DQ2- or DQ8-restricted epitopes within the C-terminal region of C-peptide that partially overlap with

126 ing question concerns the structure of the C-terminal region of CA and the peptide SP1 (CA-SP1), whic

127 The C-terminal region of cardiac troponin T (TnT), a tropomyos

128 ral and biochemical analysis show that the C-terminal region of Chz1 (Chz1-C) harbors a conserved DEF

129 ctivation of myocardial contraction by the N-terminal region of cMyBP-C in its different phosphorylat

130 ologically active peptide derived from the C-terminal region of collagen alpha3(IV) chain, a structur

131 a structural description of the Fn binding N-terminal region of CshA, derived from a combination of X

132 CsMAF1 for CsC34 interaction, whereas the C-terminal region of CsMAF1 is essential for PthA4 binding

133 Heat shock protein 90 (HSP90) binds to the N-terminal region of CTA1 and facilitates its ER-to-cytoso

134 mAb designated 2E8 does not recognize the C-terminal region of DENV NS1 in which host-cross-reactive

135 otentially harmful events, we replaced the C-terminal region of DENV NS1 with the corresponding regio

136 ctivation is surprisingly derived from the N-terminal region of DgcB itself.

137 terize a minor conformational state of the C-terminal region of DHFR.

138 nd structural approaches, we find that the C-terminal region of DRC2 is critical for the coassembly o

139 ol II subunit RPB12 and the phosphorylated C-terminal region of DSIF subunit SPT5.

140 n at Y102 disrupts the helical fold of the N-terminal region of E2 and its interaction with key cellu

141 non-synonymous substitution (A120G) in the N-terminal region of eIF2Bbeta was responsible for the TuM

142 The 6 aa at C-terminal region of ESAT-6 are essential for ESAT6:beta2M

143 n an earlier study, we have shown that the C-terminal region of ESAT-6 is crucial for its interaction

144 In contrast, the C-terminal region of Ets-1, including its Pointed (PNT) do

145 The peptide derived from the N-terminal region of Evasin-4 possessed nanomolar affinity

146 7 and found that Cys(6) and Cys(23) in the N-terminal region of ficolin-3 form the intermolecular dis

147 MVD-causing mutations are clustered in the N-terminal region of FLNA.

148 Finally, we demonstrate that the C-terminal region of FOXN1 is required for high-affinity D

149 sugar modifications and revealed that the C-terminal region of FUS is sufficient to retain ASOs in c

150 runcating or missense variants in the same C-terminal region of hnRNPR and who have multisystem devel

151 sedimentation analysis, we found that the N-terminal region of Hsp27 and the terminal regions of alp

152 Here, we present the structure of the N-terminal region of human BCAP and show that it possesses

153 nce (NMR) analysis to demonstrate that the C-terminal region of human dynein light intermediate chain

154 rimarily at the dimer interface and at the C-terminal region of IFN-gamma.

155 bine the CsgG nanopore with the 35-residue N-terminal region of its extracellular interaction partner

156 We conclude that Delta-JDBD, and not the N-terminal region of JBP1 alone, is a distinct folding uni

157 P interacts extensively with the N-terminal region of L, burying more than 4,016 angstrom(2

158 nteracting motif 2 (PAM2w) featured in the N-terminal region of LARP4A was found to be important for

159 Accordingly, the N-terminal region of LEAP2 is able to inhibit ghrelin-indu

160 noprecipitated the recombinantly expressed N-terminal region of LRP2.

161 The C-terminal region of LRRK2 is a Trp-Asp-40 (WD40) domain w

162 interface to a few acidic residues in the N-terminal region of MAD1, and point mutations in this seq

163 toplasmic loop is adjacent to the proximal C-terminal region of mouse melanopsin in the inactive conf

164 We have identified a C-terminal region of MTBP (the CTM domain) that binds effi

165 TFAM tethers the N-terminal region of mtRNAP to recruit the polymerase to t

166 Two of these mutations are located in the C-terminal region of mu1, which has not previously been im

167 ith different degrees of truncation in the C-terminal region of NBD2 reveal the importance of the las

168 catalytic activity, and suggests that the C-terminal region of NEIL3 is involved in both DNA damage

169 allow pocket adjacent to the groove in the N-terminal region of NHR trimer as a new drug target, and

170 Consistent with a role for the C-terminal region of NKAP in embryogenesis, nkap mutant ze

171 These mutations are clustered in the C-terminal region of NKAP where NKAP interacts with HDAC3

172 dicates that dramatic rearrangement of the C-terminal region of Nop15 in the pre-ribosome exposes the

173 nded alpha-helix from the disordered carboxy-terminal region of nucleoprotein-core links nucleoprotei

174 s involve the intrinsically disordered and N-terminal region of NUP98 with over 30 partner genes.

175 Alterations in the N-terminal region of OsDGAT1-1 gene revealed its regulator

176 The C-terminal region of p130Cas or Cas family homology domain

177 Using the cytosolic C-terminal region of p22phox as bait to screen a human spl

178 However, how the N-terminal region of PDZD11 interacts with the N-terminal

179 -helix binds to other alpha-helices in the C-terminal region of predominantly one of the beta-subunit

180 elic variants, antibodies elicited against C-terminal region of protein did not correlate with epidem

181 cleaved eight amino acid residues from the N-terminal region of Prx1 inside the matrix, without inter

182 by TSP1, which directly interacts with the N-terminal region of PTX3.

183 binding to polar residues in the conserved N-terminal region of PulG, we propose that PulM acts as ch

184 A conserved N-terminal region of RALF23 is sufficient for the biochemi

185 The interaction occurred through the C-terminal region of RING1B (C-RING1B), with an affinity i

186 Here we show that, although the N-terminal region of RNF4 bears no secondary structure, it

187 Moreover, the C-terminal region of SNX3 recruits galectin-9, a lectin im

188 roscopy, we demonstrate that the conserved N-terminal region of SPR1 and its GGG motif are necessary

189 Expression of the N-terminal region of SS4 alone did not alter the ss4 mutan

190 Interestingly, the N-terminal region of SS4 alone or when fused to GS conferr

191 d versions of SS4 and a fusion between the N-terminal region of SS4 and GS in the Arabidopsis ss4 mut

192 Remarkably, fusion of the N-terminal region of SS4 to A. tumefaciens GS restored the

193 Furthermore, the C-terminal region of SSX confers preferential affinity to

194 Recent data demonstrate that the N-terminal region of tau (aa 2-18), termed the "phosphatas

195 The C-terminal region of TDP-43 was required for this function

196 Overall, in addition to the N-terminal region of the B-chain, which was shown to serve

197 is based on the major NPNA repeat and the C-terminal region of the circumsporozoite protein (CSP).

198 Additionally, we show that the C-terminal region of the citrus TFIIIB component BRF1 comp

199 While the N-terminal region of the G-patch always folds into an alph

200 Here we show that the C-terminal region of the HSV-1 pUL25 protein is required f

201 lfide bonds, a structure homologous to the N-terminal region of the human granulin protein.

202 caused by a polyglutamine expansion in the N-terminal region of the huntingtin protein (N17).

203 t toxicity of the polyglutamine-containing N-terminal region of the huntingtin protein encoded by exo

204 Polyglutamine expansion within the N-terminal region of the huntingtin protein results in the

205 The N-terminal region of the huntingtin protein, encoded by ex

206 ently, an allosteric binding pocket in the C-terminal region of the ligand-binding domain (LBD) of RO

207 Additionally, the C-terminal region of the linker forms previously unreporte

208 The sequence-variable N-terminal region of the M protein defines the M type and

209 Here, we show that phosphorylation at the N-terminal region of the mitochondrial calcium uniporter (

210 entified a highly conserved motif near the C-terminal region of the PP2C.D catalytic domain that is r

211 The N-terminal region of the protein allows the interaction of

212 vel RNA recognition features involving the N-terminal region of the protein that exists in a semi-dis

213 O homooligomerization, mediated by the amino-terminal region of the protein, and carboxyl-terminal ta

214 on affecting structural aspects of the amino-terminal region of the protein, and support the concept

215 er that the major ATRX RBR lies within the N-terminal region of the protein, distinct from its PHD an

216 We focus on the C-terminal region of the protein, which comprises a membra

217 hosphorylation of an array of sites in the C-terminal region of the protein.

218 ciation of antimicrobial activity with the C-terminal region of the protein.

219 mediated by the coiled-coil domain at the N-terminal region of the protein.

220 reveals that FliD is pentameric, with the N-terminal region of the protomer forming an extensive set

221 Using the disordered N-terminal region of the Sic1 protein as a test case, we e

222 healthy donors responded similarly to the C-terminal region of the spike proteins of the human endem

223 .0015, and 0.0023, respectively), in the Ch5 terminal region of the thalamus (P = 0.0003), and in the

224 ith double cysteine substitutions near the N-terminal region of the TMD to study the effect of altere

225 Transgenic mice lacking the N-terminal region of the WWP2 protein show improved cardia

226 ant regulator of insulin fibrillation, the C-terminal region of this peptide is also crucial for the

227 interface of LvgA also interacts with the C-terminal region of three additional effectors, SidH, Set

228 An unstructured N-terminal region of Tim10 is necessary and sufficient to

229 ex activity, likely through binding to the C-terminal region of Tim44.

230 actions of the central part of Tm with the C-terminal region of TnI.

231 o individuals with de novo variants in the C-terminal region of TOMM70.

232 Our results show that the C-terminal region of TPX2 regulates Kif15 in vitro, contri

233 the ligand prevents optimal folding of the C-terminal region of VDR.

234 density corresponding to the immature amino-terminal region of VI indicates that in the absence of V

235 cyclin F-specific amino acid motif in the C-terminal region of Vif indicated rescue of the protein f

236 Mutagenesis of the C-terminal region of Vpu from two clade C viruses led to t

237 missense variants predicted to affect the N-terminal region of WDR37-p.Ser119Phe, p.Thr125Ile, p.Ser

238 ine-rich motifs (HLMs), spread in the long C-terminal region of yeast Dcp2 decapping enzyme.

239 tudies show critical roles for both an amino-terminal region of Zta and the basic DNA binding domain

240 rpin peptides derived from the central and C-terminal regions of Abeta, which bear "tails" derived fr

241 amolecular interactions between the N- and C-terminal regions of alpha-Syn, resulting in the protein

242 that the N-terminal region of Hsp27 and the terminal regions of alphaB-crystallin are important for

243 evaluate pairwise interactions between the N-terminal regions of CESA1, CESA3, CESA5, CESA6 and the c

244 he FG/GLFG region of Nup98 binds to N- and C-terminal regions of DHX9 in an RNA facilitated manner.

245 t are localized within and adjacent to the C-terminal regions of each homodimer.

246 gical settings that do not correspond to the terminal regions of Greenland outlet glaciers that we st

247 ition of acetylated lysine residues in the N-terminal regions of histones.

248 ragmentation that allows mapping of N- and C-terminal regions of large proteins without the need for

249 interactions were not provided, as the amino-terminal regions of murine and human TRPC6 were not reso

250 ly conserved amino acid differences in the N-terminal regions of Pgamma isoforms, demonstrating for t

251 We find that both the N- and C-terminal regions of Sca2 interact with actin monomers bu

252 estigated the specific roles of the N- and C-terminal regions of SS4 by expressing truncated versions

253 Both N-terminal and C-terminal regions of tamalin played critical roles in mGl

254 patients were significantly lower in the Ch4 terminal regions of the anterior cingulate cortex and th

255 ate RTS,S/AS01 is based on the central and C-terminal regions of the circumsporozoite protein (CSP) o

256 Differential localization of N- and C-terminal regions of the collagen VI alpha3 chain reveale

257 of DLD-4-1.4E and U3-bind the central and C-terminal regions of the delivery domain of TcdB.

258 electrophoretic mobility originate in the C-terminal regions of the gamma-tubulins.

259 e of the JCI, Xu et al. show that specific C-terminal regions of the MOR can modulate side effects wi

260 ing it contact the N-terminal, middle, and C-terminal regions of the peptide.

261 topological stress require distinct N and C terminal regions of the protein, whereas the other funct

262 such as the zinc-binding motif and N- and C-terminal regions of the protein.

263 previously shown to occur frequently at the terminal regions of the secondary structures, the propen

264 Through manipulation of the C-terminal regions of these proteins we show the SPKTG mot

265 The N-terminal regions of these variants were essential for st

266 however, additionally have low-complexity N-terminal regions of unknown function.

267 of 1:2, unsaturated binding of YoeB to the C-terminal regions of YefM dimer forms an optimal heterohe

268 Although the extended transmembrane Orai N-terminal region (Orai1 amino acids 73-91; Orai3 amino ac

269 viral membrane fusion by lifting the MPER N-terminal region out of the viral membrane, mandating the

270 and HO1 and indicate that their dissimilar C-terminal regions play a major role in controlling the st

271 in nine amino acid residues in their very C-terminal regions, play distinct roles in neurogenesis.

272 novo non-synonymous variants involving the C-terminal region presented a more severe phenotype with a

273 o produce a bicyclic peptide to target the C-terminal region (residues 31-42) of the 42-residue form

274 g CyRPA and RIPR, and contains a conserved N-terminal region (RH5Nt) of unknown function that is clea

275 because it did not seem to contain a RecQ C-terminal region (RQC) found in the other RecQ paralogues

276 re-forming alpha1 subunit and, through its C-terminal region, scaffolds the beta subunit of VGCC and

277 Ahnak, through its N-terminal region, scaffolds the L-type pore-forming alpha

278 VK210, VK247 and P. vivax-like) and of the C-terminal region (shared by all PvCSP variants) in natura

279 aramagnetic lanthanide ion attached to its N-terminal region shows a decrease in alignment as the dis

280 midbrain DA cells and promotes DA release in terminal regions such as the nucleus accumbens (NAc).

281 CH1 to bind actin aided by an unstructured N-terminal region that becomes alpha-helical upon binding.

282 ereas reintroduction of AKAP8L missing the N-terminal region that confers the interaction with mTORC1

283 mbination and identify regions of the RAG1 N-terminal region that control nucleolar association and e

284 F4 consists of an intrinsically disordered N-terminal region that interacts with other super-elongati

285 ocalization signal within an unstructured, N-terminal region that is rich in serine and threonine res

286 , the structures contain a large, flexible N-terminal region that was investigated by gel-filtration

287 2 has non-canonical features in its N- and C-terminal regions that explain its poor interaction with

288 luble protein (Delta-JDBD) with the N- and C-terminal regions tightly associated together in a well-o

289 Nrd1 can partially substitute for the Set1 N-terminal region to restore CTD interactions and histone

290 peptide, designated NC1-peptide, from the C-terminal region, via the action of MMP-9 (matrix metallo

291 CROPS [combined repetitive oligopeptides]) C-terminal region, was shown to elicit protective immunity

292 ast two beta-strands in NBD2 and the whole C-terminal region, we further characterized truncation mut

293 Non-amyloid component and C-terminal regions were consistently found to contain beta

294 d N-terminal and positively charged middle/C-terminal regions, whereas hydrophobic interactions play

295 structure revealed a unique alpha-helical C-terminal region which we demonstrated to be essential fo

296 T-tubule membrane through their cytosolic N-terminal region, which contains 8 lipid-binding (MORN) m

297 minal catalytic domain but differ in their N-terminal region, which is composed of 4 repeats of scave

298 ssociates with LDs through its hydrophobic N-terminal region, which is sufficient to demarcate sites

299 cking of the residues from the central and C-terminal regions, with the N-terminus of Abeta accommoda

300 mide shifts are localized mostly to N- and C-terminal regions within the rigid beta structure in the