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1 esyl diphosphate synthase and an appropriate terpene synthase.
2  Phomopsis amygdala (PaFS) is a bifunctional terpene synthase.
3 P, C(17) ), serving as the substrate for the terpene synthase.
4 -component protein located downstream of the terpene synthases.
5 hetic properties in phylogenetically related terpene synthases.
6 ranscripts for eight genes encoding distinct terpene synthases.
7  shows some similarity to sequences of other terpene synthases.
8 al products by providing a homologous set of terpene synthases.
9 lly related to the family of proteins termed terpene synthases.
10 s phylogenetically unique and possesses nine terpene synthases.
11 Ts) through the activities of microbial-type terpene synthases.
12 es these enzymes in a noncanonical family of terpene synthases.
13 ases and only distantly so to microbial-type terpene synthases.
14 scades and promiscuity mechanisms of class I terpene synthases.
15 acilitate the functional assignment of novel terpene synthases.
16 rase mechanism of UbiX resembles that of the terpene synthases.
17 istent with proposed evolutionary origins of terpene synthases.
18 o catalytic activity of 10 additional tomato terpene synthases.
19 r helices rather than six found in all other terpene synthases.
20 tative sesquiterpene synthase (M. truncatula TERPENE SYNTHASE 10 [MtTPS10]) in both developmental sta
21 ery and mechanistic analysis of golden larch terpene synthase 8 (PxaTPS8), an unusual diterpene synth
22 functionalization of a compartment-switching terpene synthase accepting a novel substrate in the plas
23 site moonlighting on it and the first time a terpene synthase active site is found moonlighting on an
24 y structure indicate the presence of a novel terpene synthase active site that is moonlighting on the
25  will aid the prediction and design of novel terpene synthase activities towards clean monoterpenoid
26 erpenes were correlated with total levels of terpene synthase activities, and negatively correlated w
27 lishes that this barrel is essential for the terpene synthase activity of CYP170A1 but not for the mo
28 3) whose members have a characteristic alpha terpene synthase alpha-helical fold.
29  well as structural comparisons with diverse terpene synthases and cyclases which clearly separate th
30  families of conifer defense metabolism, the terpene synthases and cytochrome P450s.
31 tandardized method to facilitate analysis of terpene synthases and diverse mutant enzyme libraries by
32 s, not related to previously described plant terpene synthases and only distantly so to microbial-typ
33 thetic strategy in maize, where multiproduct terpene synthases and promiscuous P450s collaboratively
34 c gene cluster, verified the function of the terpene synthase, and heterologously produced the core d
35 rate orientation, not previously observed in terpene synthases, and visualize a series of trapped hyd
36 nscript levels of a gene encoding a putative terpene synthase are induced in mechanically- or insect-
37                                              Terpene synthases are a mechanistically intriguing famil
38    Among the annotated protein-coding genes, terpene synthase, auxin-regulatory factors, GRFS, ANK_RE
39 ween two distinct yet evolutionarily related terpene synthases based on the systematic identification
40  isoprene depends on whether or not it has a terpene synthase capable of using dimethylallyl diphosph
41                               "Head-to-head" terpene synthases catalyze the first committed steps in
42 ugh advances in cereal genome annotation and terpene synthase characterization that likewise enable d
43 e gene level by RNA-blot hybridization using terpene synthase class-directed DNA probes.
44 te into a C(17) diphosphate precursor, which terpene synthases convert into distinct C(17) scaffolds.
45 sh revealed a total of 33 different cannabis terpene synthase (CsTPS) genes, as well as variations of
46                          Here we report on a terpene synthase (DdTPS8)-cytochrome P450 (CYP521A1) gen
47                                        While terpene synthases derived from isoprenyl diphosphate syn
48 crystallography, pointing the way for future terpene synthase design.
49        Over deep evolutionary time, as plant terpene synthases diversified in plants, so did plant te
50 thematical model in order to construct novel terpene synthases, each catalysing the synthesis of one
51                                          The terpene synthase encoded by the sav76 gene of Streptomyc
52                 Here we report that only two terpene synthases, encoded by the florally expressed gen
53 s are produced in our system by changing the terpene synthase enzyme.
54 rgy surfaces, but also for the mechanisms of terpene synthase enzymes and their evolution.
55 ortance of inherent substrate reactivity for terpene synthase enzymes is discussed, with a focus on r
56 ases make the active site smaller than other terpene synthase enzymes, possibly conferring specificit
57       Phylogenetic analysis shows that C(17) terpene synthases evolved multiple times from C(16)-asso
58 ied out with OsCPSsyn revealed that class II terpene synthases exhibit a sequence conservation patter
59 esting a very distant ancestor to the larger terpene synthase family.
60   Mutations of residues outside of the alpha terpene synthase fold are important for acquisition of F
61 ach subunit adopts the alpha-helical class I terpene synthase fold with the active site in the "open"
62         The biochemical function of all four terpene synthases found in the S. avermtilis genome have
63          Here, we show that 125 (37%) of 334 terpene synthases from 8 phyla, 17 classes, and 83 gener
64 this gymnosperm do not very closely resemble terpene synthases from angiosperm species (52-56% simila
65             Interestingly, distantly related terpene synthases from fungi to plants all contain an in
66          Based on their sequence similarity, terpene synthases from land plants can be divided into d
67 pression of SgATG8a in Arabidopsis increased terpene synthase gene (SgTPS) expression, leading to the
68 dicates that other such class I and class II terpene synthase gene clusters may similarly catalyze co
69 T1, SlCPT2 and SlCPT6) are closely linked to terpene synthase gene clusters.
70 expressed exclusively in the flowers and one terpene synthase gene expressed almost exclusively in th
71                 Phylogenetic analysis of the terpene synthase gene family indicated that isoprene syn
72 uction of any terpenoid compound for which a terpene synthase gene is available.
73             The maize (Zea mays subsp. mays) terpene synthase gene stc1 is part of that indirect defe
74                                   mRNA for a terpene synthase gene, phellandrene synthase 1 (PHS1), w
75                                              Terpene synthases generate terpenes employing diversifie
76                                      Class I terpene synthases generate the structural core of bioact
77 t not only increased the expression level of terpene synthase genes (SgTPSs) but also led to enhanced
78      Here we report that fungi have acquired terpene synthase genes (TPSs), which encode pivotal enzy
79 esources, we identified seven V. officinalis terpene synthase genes (VoTPSs), two that were functiona
80 to eight previously characterized angiosperm terpene synthase genes and to six putative terpene synth
81 , the phylogenetic analysis revealed the two terpene synthase genes as primitive genes that might hav
82                                          Two terpene synthase genes expressed exclusively in the flow
83                                    Candidate terpene synthase genes for the production of 1,8-cineole
84  a HMMER search tool to identify 17 putative terpene synthase genes from M. polymorpha transcriptomes
85 on of P450 genes with their adjacent located terpene synthase genes in E. coli demonstrates that the
86                                    Of the 32 terpene synthase genes in the Arabidopsis genome, 20 wer
87                            The enrichment of terpene synthase genes in the MYC2-regulated gene set su
88 r natural products biosynthesis derived from terpene synthase genes involved in primary metabolism by
89                                              Terpene synthase genes involved in the biosynthesis of t
90                    Three distinct classes of terpene synthase genes were discerned, from which assume
91                                          New terpene synthase genes were isolated from flowers of Nic
92       LcNAC1 regulates the expression of two terpene synthase genes, LcTPSa1 and LcTPSa2, which belon
93 late E7406B, we were able to identify 11 new terpene synthase genes.
94 ra of rhizobia were found to have homologous terpene synthase genes.
95 m terpene synthase genes and to six putative terpene synthase genomic sequences from Arabidopsis thal
96 n of (S)-beta-citronellol commences with the terpene synthase GES1 catalyzing the irreversible conver
97            An unusual family of bifunctional terpene synthases has been identified in which a prenylt
98  in many natural water supplies; however, no terpene synthases have been characterized from these org
99                           Although these two terpene synthases have very similar catalytic properties
100 rly separate the terpene cyclases from other terpene synthases having highly alpha-helical structures
101 gement in the greater family of bifunctional terpene synthases, hundreds of which have been identifie
102                                   The second terpene synthase in N. punctiforme (NP2) is homologous t
103 so report the identification of bifunctional terpene synthases in an animal, Adineta steineri, a bdel
104 c 'insertional' sequence element in class II terpene synthases, indicating that this region is import
105 wledge, this is the first documentation of a terpene synthase involved in the synthesis of a linear t
106                      Rational engineering of terpene synthases is challenging due to a lack of correl
107               However, directed evolution of terpene synthases is hampered by the lack of a convenien
108 , which is cyclized by an unusual plastidial terpene synthase (LfTPS1) into the characteristic serrul
109 hem were nine putative full-length microbial terpene synthase-like (MTPSL) genes designated DfMTPSL1-
110 ic catalysis of abietadiene cyclization, and terpene synthases more broadly.
111 thase NS1) and Nostoc punctiforme PCC 73102 (terpene synthases NP1 and NP2).
112                                              Terpene synthases NP1 and NS1 are part of an apparent mi
113 es identified in Nostoc sp. strain PCC 7120 (terpene synthase NS1) and Nostoc punctiforme PCC 73102 (
114  and analysis of six genomic clones encoding terpene synthases of conifers, [(-)-pinene (C(10)), (-)-
115                                              Terpene synthases often catalyze complex cyclization rea
116                                              Terpene synthases often catalyze complex reactions invol
117                                              Terpene synthases orchestrate complex cyclization cascad
118 thetic pathway spans seven enzyme families-a terpene synthase, P450s, nucleotide sugar synthases, gly
119    Interestingly, defense modulators such as terpene synthase, papain-like cysteine protease, serine
120 PS1ent in maize (Zea mays) than its class II terpene synthase paralogs involved in rice secondary met
121  high degree of structural relatedness among terpene synthases, previous studies suggest that no clea
122                                              Terpene synthases produce a remarkable structural divers
123                                 The class II terpene synthase producing syn-copalyl diphosphate from
124                     Substrate promiscuity of terpene synthases provides organism access to novel chem
125                               Promiscuity of terpene synthases results in the enormous diversity of t
126 uctural elucidation of 28 diterpenes from 31 terpene synthases reveal three previously unreported ter
127 rgent evolution, mutational analysis of this terpene synthase revealed an active site asparagine crit
128                             Accordingly, how terpene synthases specify product outcome has drawn a gr
129 me implications regarding the means by which terpene synthases specify product outcome.
130 sented for the evolutionary history of plant terpene synthases suggests that this superfamily of gene
131 urprising finding of an atypical class I (di)terpene synthase that acts on CPP to produce the abietan
132 natural products is catalyzed by the class I terpene synthase that converts syn-copalyl diphosphate t
133                           Thus, the class II terpene synthase that converts the universal diterpenoid
134 ene synthase (ZIS) gene encoding a cytosolic terpene synthase that has been shown to possess both ses
135 says, we identified ZmTPS9 as a multiproduct terpene synthase that primarily produces alpha-santalene
136  challenges for the functional assignment of terpene synthases that construct the carbon skeletons of
137 (E)-beta-farnesene synthase (BFS), a pair of terpene synthases that produce cyclic or linear terpenes
138 lly the alpha, alphabeta, and alphabetagamma terpene synthases that produce plant terpenes, with many
139 ata were used to identify eight putative (di)terpene synthases that were then characterized for their
140 nome mining reveals widespread prevalence of terpene synthases, the enzymes responsible for construct
141   These modified diphosphates were used with terpene synthases to produce the unnatural sesquiterpeno
142 into the evolutionary relationship of fungal terpene synthases to those in plants and bacteria and fu
143 terpenes called rhizathalenes by the class I terpene synthase (TPS) 08 in roots of Arabidopsis thalia
144 s could be assigned to previously identified terpene synthase (TPS) activities that included members
145  Four of these putative trans-IDSs exhibited terpene synthase (TPS) activity when heterologously expr
146  trans-prenyltransferase (PT) and N-terminal terpene synthase (TPS) domains.
147 hase (GLS) belonging to the e/f clade of the terpene synthase (TPS) family and two Fabaceae GLSs that
148 -seq) and metabolite analysis to unravel the terpene synthase (TPS) family contributing to wound-indu
149 4 (At1g61680), define a new subfamily of the terpene synthase (TPS) family designated the Tps-g group
150  Here, we describe the identification of the terpene synthase (TPS) gene family of the panicoid food
151                 Three cDNAs corresponding to terpene synthase (TPS) genes expressed in young leaves w
152 t induction of expression of seven of the 11 terpene synthase (TPS) genes identified through the micr
153       Here, we functionally characterized 19 terpene synthase (TPS) genes in an orange carrot (genoty
154 Functional verification of tandem duplicated terpene synthase (TPS) genes reveals that genes within i
155 ed tomato (Solanum lycopersicum) contains 44 terpene synthase (TPS) genes, including 29 that are func
156 apple (Malus domestica) contains 55 putative terpene synthase (TPS) genes, of which only 10 are predi
157 sesquiterpene biosynthesis in sorghum, seven terpene synthase (TPS) genes, SbTPS1 through SbTPS7, wer
158 he L. longipalpis genome revealed a putative terpene synthase (TPS), which-upon heterologous expressi
159 noid biosynthesis in some insects, canonical terpene synthases (TPS) commonly found in plants, fungi,
160                                         Four terpene synthases (TPS) from the TPS-a subfamily, includ
161 enes found in nature is mainly determined by terpene synthases (TPS).
162 e show that all four selected genes, the two terpene synthases (TPS10 and TPS14) and the two cytochro
163 ism in the promoter of the gene encoding the terpene synthase TPS2 with this QTL Biochemical characte
164 d fold changes included transcripts encoding terpene synthases (TPSs) and peroxidases (POXs) that cor
165                                              Terpene synthases (TPSs) and trans-isoprenyl diphosphate
166                                              Terpene synthases (TPSs) are pivotal enzymes for the bio
167  has been well studied, with most if not all terpene synthases (TPSs) being identified.
168                The extensive family of plant terpene synthases (TPSs) generally has a bi-domain struc
169  described in plants and microorganisms, few terpene synthases (TPSs) have been identified in insects
170                                  To identify terpene synthases (TPSs) involved in the production of t
171                       In plants, a family of terpene synthases (TPSs) is responsible for the synthesi
172 lycopersicum; Solanaceae) contains genes for terpene synthases (TPSs) that specify the synthesis of m
173 he pivotal enzymes for terpene biosynthesis, terpene synthases (TPSs), had been described only in pla
174  contains over 30 genes potentially encoding terpene synthases (TPSs).
175 of a large gene family (with 20 members) for terpene synthases (TPSs).
176  validation, we identified a group of type I terpene synthases (TSs) from this sponge and multiple ot
177 -dependent cyclization cascades catalyzed by terpene synthases (TSs).
178  structure of a massive, 495-kD bifunctional terpene synthase, variediene synthase from Emericella va
179 nd phase, and exon size) of these gymnosperm terpene synthases was compared to eight previously chara
180  and terpenoid compounds, including putative terpene synthases, were first identified by mining publi
181  taxadiene synthase (TXS), the model class I terpene synthase, which simulates the initial catalytic
182                   Of particular interest are terpene synthases, which often mediate the committed ste
183                                              Terpene synthases, which synthesize monoterpenes and ses
184  our knowledge, this is the first identified terpene synthase with this particular substrate stereose

 
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