ライフサイエンスコーパス: the cause of

1 Metastasis is the cause of 90% of mortality in cancer patients.

2 pecific SOX4 HMG-domain missense variants as the cause of a characteristic human neurodevelopmental d

3 two variables, and in the identification of the cause of a given variable.

4 Our study therefore explains the cause of a major limitation in current proteome-wide

5 We describe bi-allelic RINT1 alterations as the cause of a multisystem disorder including RALF and s

6 We identify SLC12A2 de novo mutations as the cause of a novel neurodevelopmental disorder and bil

7 yndrome coronavirus 2 (SARS-CoV-2), which is the cause of a present pandemic, infects human lung alve

8 lymerase delta1 catalytic subunit (POLD1) as the cause of a primary immunodeficiency in an extended k

9 lopment and supporting mutations in ZMIZ1 as the cause of a rare neurodevelopmental syndrome.

10 s and mice indicate that IQSEC1 variants are the cause of a recessive disease with intellectual disab

11 Nevertheless, it took until 2013 to identify the cause of a relatively frequent inborn error, pseudox

12 gans such as the skin and the brain) and are the cause of a sometimes fatal condition in patients, ne

13 We report DEGS1 dysfunction as the cause of a sphingolipid disorder with hypomyelinatio

14 me coronavirus 2 (SARS-CoV-2) has emerged as the cause of a worldwide pandemic.

15 ndamentally challenge current conceptions of the causes of ADHD in ways that might have the potential

16 Understanding the cause of allometric scaling has been a long-standing

17 However, the causes of altered gut barrier remain mostly unknown.

18 atory syndrome coronavirus 2 (SARS-CoV-2) is the cause of an ongoing pandemic that has infected over

19 atory syndrome coronavirus 2 (SARS-CoV-2) is the cause of an ongoing pandemic, with increasing deaths

20 9), was first discovered in December 2019 as the cause of an outbreak of pneumonia in the city of Wuh

21 nd mirtrons.CONCLUSIONWe identified DGCR8 as the cause of an unreported autosomal dominant mendelian

22 CANTOS was not designed to assess the cause of anemia in individual trial participants.

23 ivors generally undergo a workup to identify the cause of arrest.

24 L* proteins of DA-C(L) variant, which may be the cause of attenuating phenotype of DA-C(L) variant in

25 d that allow for further characterization of the cause of atypical optic neuritis: AQP4-IgG and MOG-I

26 The cause of autosomal-dominant retinitis pigmentosa (ad

27 The cause of belatacept-resistant graft rejection was al

28 However, analysis of transcriptomic data, the cause of biological and pathological changes, is ham

29 To determine the cause of blotched flowers, we focused on an endogeno

30 We performed experiments to clarify the causes of BrdU-gammaH2AX double labeling in mouse an

31 However, the causes of CA in human cancer are unclear.

32 expression profiles has provided insight on the causes of cancer and cancer treatment.

33 figuration (AAAGG)10-25(AAGGG)exp, which was the cause of CANVAS in all patients.

34 2 issues: the most current understanding of the causes of cardiomyopathy in children and the optimal

35 ECMO is particularly effective if the cause of cardiopulmonary failure is recognized promp

36 botic microangiopathy should be screened for the causes of CD.

37 To investigate the causes of cell-to-cell variation in proliferation, w

38 The causes of Cenozoic uplift of the Colorado Plateau, s

39 plication factor complex subunit 1 (RFC1) as the cause of cerebellar ataxia, neuropathy, vestibular a

40 In chronic Trypanosoma cruzi infection, the cause of Chagas disease, life-threatening inflammato

41 teins was identified in the alb3b strains as the cause of changes in the spectral properties of the m

42 defects in the suprachiasmatic nuclei (SCN), the cause of circadian disruption in HD remains to be fu

43 , carotid stenosis of 70% and above might be the cause of clinical symptoms such as transient ischemi

44 can be immunogenic in man and are frequently the cause of clinically important immune reactions respo

45 ese alterations in the gene content could be the cause of CMS in the cybrid.

46 Identifying the causes of compromised cardiac function in this patie

47 The results expand our understanding of the causes of congenital malformations and the importanc

48 The causes of continental patterns in species richness c

49 iratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has sp

50 iratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), is ass

51 ronavirus 2 (SARS-CoV-2) emerged in China as the cause of coronavirus disease 2019 in December 2019 a

52 iratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19, provide opportunities to study as

53 iratory syndrome coronavirus 2 (SARS-CoV-2), the cause of COVID-19.

54 Several factors have been implicated in the cause of Crohn's disease, including a dysregulated i

55 The cause of CSF leakage was identified in 49 of 65 epis

56 aboratories, led to greater understanding of the causes of CVD, to a vigorous practice of preventive

57 While the cause of DA cell loss in PD is unknown, male sex is

58 Determining the cause of deafness in individuals without previous fa

59 Variations in determining the cause of death (metastatic or nonmetastatic) may be

60 However, sometimes the cause of death cannot be determined from available d

61 A possible relationship was found between the cause of death category and microplastic abundance,

62 he number of deaths from each cause, through the Cause of Death Ensemble model algorithm, using CoDCo

63 Of these, the cause of death for 1566 (90.7%) children in the azit

64 of liver function or overt liver failure as the cause of death in COVID-19 rarely occur.

65 In some cases, the cause of death may be evident on autopsy; however, i

66 The cause of death was determined for each case by an in

67 a review committee confirmed lung cancer as the cause of death when possible.

68 thought to be a contributing factor, but not the cause of death, for both.

69 rrhythmias, standard autopsy will not reveal the cause of death.

70 In 269 (80%) we could not determine the cause of death.

71 S) network aims to generate reliable data on the causes of death among children aged <5 years using a

72 However, little is known about the causes of death and the virus's pathologic features.

73 The significant difference in the causes of death between patients with alcohol AP and

74 Bill & Melinda Gates Foundation to identify the causes of death in children in communities with high

75 We describe the causes of death in EUCLID using mortality end points

76 ease still occupies a leading position among the causes of death worldwide.

77 and 97,068 AMI patients via the patient- and the cause-of-death registers and linked to prescription

78 The cause of decreased HIV incidence has been attributed

79 um permeable ion channel, were identified as the cause of DEE in eight probands, but the functional c

80 ol experiments were performed to investigate the cause of degrading selectivity under the CEC reactio

81 events' maximum temperature and duration as the cause of devastating disturbances in coral reefs, ke

82 ic mortality is frequent in animals although the causes of different male versus female mortalities r

83 ], <=0.0001) CFH variants were identified as the cause of disease in each family: CFH c.1243del, p.(A

84 for research to further our understanding of the causes of disease.

85 We also explored the causes of diverse infection outcomes across replicat

86 ma levels did not support HIV replication as the cause of DS from the genital tract.

87 The causes of each of these trends require further inves

88 agalactiae or group B Streptococcus (GBS) is the cause of early- and late-onset GBS disease in neonat

89 implicated in promoting age-related decline, the causes of early-onset aging defects are unknown.

90 l mouse mutant lines in order to investigate the causes of embryonic lethality.

91 g consequences to patients' quality of life, the causes of endometriosis are not fully understood and

92 Thus, the causes of epistasis in the wild remain poorly unders

93 ight or obese, and more likely to have GN as the cause of ESRD.

94 n the ongoing nationwide investigations into the cause of EVALI.

95 However, the causes of evolutionary constraint have remained elus

96 ted expressions of cyclooxygenase-2 might be the cause of excessive neuronal demise in the striatum o

97 Ranaviruses have been identified as the cause of explosive disease outbreaks in amphibians w

98 as an increased trend for RPI in cases where the cause of extraction was persistent apical periodonti

99 ly affected cutaneous melanoma families, and the causes of familial clustering in the remainder are u

100 ng the difficulty in accurately ascertaining the causes of fatal anaphylaxis and therefore in assigni

101 Here, we have explored the cause of filamentation and identified a potentially

102 rently, and this limits our understanding of the causes of fine-root evolution.

103 Our objective was to assess the causes of gastroenteritis among MSM living with and

104 Finally, given that the cause of gastroparesis remains largely idiopathic, o

105 The cause of geographic atrophy (GA), a progressive dry

106 However, identifying the cause of GI pain frequently represents a diagnostic

107 ognizing the need for better primary data on the causes of global child mortality, the Bill & Melinda

108 and alloimmune, to gain better insight into the causes of graft failure.

109 e and allo-immune, to gain better insight in the causes of graft failure.

110 first Granger causality analysis to identify the "causes" of groundwater patterns using the rice-prod

111 y has long been concerned with understanding the causes of health and disease states so that we can i

112 to the nervous system) during the search for the cause of hepatopathy with very low values of serum c

113 epidermal growth factor receptor 2 (HER2) is the cause of HER2-positive breast cancer (BC).

114 e ultimate source of all genetic novelty and the cause of heritable genetic disorders.

115 ine abdominal MRI was performed to determine the cause of his symptoms and to assess the pancreas (Fi

116 ine abdominal MRI was performed to determine the cause of his symptoms and to assess the pancreas.

117 tpatient departments (HOPDs) and to describe the causes of hospital visits.

118 Mycobacterium tuberculosis, the cause of human tuberculosis, and Mycobacterium marin

119 bon supply, as opposed to excess glycine, is the cause of hydrocephalus associated with loss of funct

120 rhizome as an ideal food material to manage the cause of hyperglycemia and resultant oxidative stres

121 Understanding the causes of immune evasion and disease progression wil

122 We demonstrate that the cause of indefinite allograft survival in the absenc

123 amentally different approach for identifying the cause of individual instances of cancer: we search f

124 indirectly detect infections and to identify the cause of infection by spectroscopic characterization

125 neutrophils challenged with pathogens, even the cause of infection, bacterial or fungal, was predict

126 ly associated with chronic inflammation, but the causes of inflammation and the specific immune media

127 es into a restorative stage after removal of the cause of injury and an increased NLRP3 / miR-223 rat

128 s with peripheral blood RNA-seq could unveil the cause of insidious late islet graft loss.

129 uously updates a hierarchical model to infer the causes of its sensory inputs.

130 le, we summarize the available literature on the causes of kidney allograft failure, both early and l

131 er, we summarize the available literature on the causes of kidney allograft failure, both early and l

132 Resolving the cause of large mammal extinctions requires greater k

133 hen discuss key knowledge gaps pertaining to the causes of legacy effects, and how the various mechan

134 However, the cause of lethality is obscure.

135 patient-specific characteristics, including the cause of limb absence (acquired or congenital) and h

136 cleoside reverse transcriptase inhibitors as the cause of lipoatrophy led to the development of newer

137 Borrelia burgdorferi was discovered to be the cause of Lyme disease in 1983, leading to seroassays

138 ies, including the role of key immune cells, the cause of lymphopenia, organ-specific immunology, the

139 ment, we revise the Conceptual Framework for the Causes of Malnutrition and Death and the Nurturing C

140 roviding a locally relevant understanding of the causes of mangrove loss.

141 ploidy, a common feature of cancer cells and the cause of many developmental diseases [1-4].

142 nderlying syndromic CS have been identified, the cause of many syndromic cases remains unknown.

143 ecognition that infectious microbes serve as the causes of many human diseases, physicians and scient

144 Little is known about the causes of meningioma.

145 Evidence suggests low-grade inflammation as the cause of metabolic syndrome and suggests diet as a p

146 that promote diversification and speciation, the causes of migratory behaviour, and how animal popula

147 Identification of the cause of MINOCA is feasible and has the potential to

148 netic mutations have now been established as the cause of mitral valve insufficiency, and four differ

149 We aimed to determine the causes of mortality among deceased children using ve

150 Although metastasis remains the cause of most cancer-related mortality, mechanisms g

151 The cause of most fetal anomalies is not determined pren

152 Further understanding of the causes of mouse aggression could have a significant

153 The causes of multiple sclerosis (MS) remain unknown.

154 Specific attention to the cause of myocardial infarction, diagnostic evaluatio

155 flammation resulting from virus infection is the cause of myocarditis; however, the precise mechanism

156 The cause of ND seems to be multifactorial and less well

157 The causes of Neanderthal-modern human (MH) turnover are

158 in the mitochondria is increasingly seen as the cause of neurodegeneration.

159 Expanded GGC repeats as the cause of NIID was further confirmed in an additional

160 The cause of obesity and one of its chief complications,

161 The causes of obesity are complex because, in addition t

162 The causes of obesity in childhood and adolescence are c

163 eived a CE examination, so as to investigate the cause of obscure GI bleeding; between July 2008 and

164 ft in beliefs (i.e., information gain) about the causes of our sensations.

165 the key brain areas and cell types mediating the cause of overdose- opioid-induced respiratory depres

166 dynamics, and function and shed new light on the causes of oxidative stress observed in PC and relate

167 ovel risk loci and gain further insight into the causes of Parkinson's disease.

168 Regarding PD, 7 articles corroborated that the cause of PD is related primarily to internal reflect

169 deep retinal plexuses may persist and may be the cause of permanent structural and functional changes

170 The cause of PG is not well understood, but PG is genera

171 However, the causes of PH are heterogeneous, and patient prognosi

172 From fundus photography grading, the cause of poor vision appeared to be macular atrophy

173 Despite research on the causes of populism and on the narratives of populist

174 fixation, pursuit, and saccades in mTBI are the cause of post-concussive symptoms, or that these abn

175 While the cause of preeclampsia is still debated, clinical and

176 Although the cause of preeclampsia, a pregnancy complication with

177 Failure to predict and understand the causes of preterm birth, the leading cause of neonat

178 th several nutritional factors implicated in the cause of psychiatric ill-health.

179 We trace the cause of PX's biostability to DNA crossovers, showin

180 acterial obligate intracellular parasite and the cause of query (Q) fever.

181 f RLT, interactive RLT (iRLT), to understand the causes of range limits and predict range shifts.

182 The cause of recurrent/intermittent rectal CT and the cl

183 These findings not only shed new light on the causes of resilience loss from cascade effects in ne

184 ermissible to MNV infection, suggesting that the cause of resistance lies in the entry step of MNV in

185 lation and restore normocapnia regardless of the cause of respiratory dysfunction.

186 We sought to determine the cause of selective T-cell lymphopenia with inverted

187 ting various drug compounds, which is one of the causes of serious nosocomial infections.

188 The cause of severe nasal polyposis in aspirin-exacerbat

189 ANCE The HSV-1 latency reactivation cycle is the cause of significant human pathology.

190 In 2012, we suggested that the cause of sleep stems from cumulative effects of nume

191 y alterations of the brain's inference about the causes of socially relevant sensory signals.

192 ta identify aging-associated inflammation as the cause of SSPC dysfunction and provide mechanistic in

193 c plaque in an epicardial coronary vessel is the cause of STEMI in the majority of cases.

194 In the majority of cases, the cause of stillbirth remains unknown despite detailed

195 nation, and clinical history, in attributing the causes of stillbirth in a South African LMIC setting

196 Nevertheless, the causes of such impairment are different for each ana

197 ls and nectar vs. pollen collection, however the causes of such variation are still open questions.

198 The causes of thalamic atrophy are not fully understood.

199 notype for an entire population reveals both the causes of that phenotype for that place and the powe

200 hough the molecular function of the gene and the cause of the apparently complex disease spectrum rem

201 vestigation, silica gel was discovered to be the cause of the byproduct formation.

202 novel koayu-specific antigen might have been the cause of the condition.

203 ed for a controlled clinical trial examining the cause of the continued bone degradation throughout o

204 SARS-CoV-2, a betacoronavirus, is the cause of the COVID-19 pandemic.

205 usceptibility and environmental factors, but the cause of the disease remains unknown.

206 The cause of the end-Cretaceous mass extinction is vigor

207 stics are needed for rapid identification of the cause of the epidemic to facilitate effective contro

208 atory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the global pandemic of coronavirus disease-

209 icate that a broad mutational target size is the cause of the high mutational variance and of the cor

210 In rare cases the cause of the hypercalcemia is excessive production o

211 Here, we investigate the cause of the hypoxia and whether it is due to a defi

212 The cause of the improved survival was unclear, as compl

213 ntingtin (HTT) protein in its mutant form is the cause of the inherited neurodegenerative disorder, H

214 We hypothesize that the cause of the lability of the N-glycosidic bond is du

215 hat T cell-mediated graft rejection could be the cause of the late-phase islet loss.

216 rties of the most pathogenic forms of HPV16, the cause of the majority of cervical cancers.

217 atory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the ongoing coronavirus disease 2019 (COVID

218 flow simulations indicate the opposite, and the cause of the opposing conclusions is not clear.

219 our findings suggest that EXOC2 variants are the cause of the patients' neurological disorders.

220 Finally, to demonstrate that Hh levels are the cause of the plastic response and not simply the con

221 he outward expanding hot electron current as the cause of the radial expansion.

222 calcitriol by this neuroendocrine tumor was the cause of the refractory hypercalcemia.

223 The cause of the renal failure in COVID-19 is unknown, b

224 We identified the cause of the S-phase requirement for silencing estab

225 that an improvement in living conditions is the cause of the shift in the human mindset toward innov

226 two experiments suggests that PM exposure is the cause of the short-term cognitive decline observed i

227 ms in condensed matter physics: agreement on the cause of the slowing down of structural relaxation i

228 tching activity has been delineated based on the cause of the switching: light, spin crossover (SCO),

229 pecific IgE test is insufficient to diagnose the cause of the symptoms, a component allergen-specific

230 Metastases are the cause of the vast majority of cancer deaths.

231 Mycobacterium tuberculosis is the cause of the world's most deadly infectious disease.

232 The causes of the extreme and persistent warming in the

233 The causes of the increased risk of severe coronavirus d

234 emical disorder and inter-band scattering as the causes of the inhomogeneity, and shed light on the r

235 The causes of the NAWH remain under debate.

236 The causes of the severest crisis in the history of life

237 red function of these ion channels is one of the causes of the thick dehydrated mucus that characteri

238 The cause of these complications is currently unknown.

239 ociations providing important insights about the cause of these diseases, which can help accelerate n

240 noply of biological processes is involved as the cause of these diseases.

241 The cause of these reactions is unknown, but they are ac

242 The causes of these asymmetries in performance are large

243 While more studies are needed to understand the causes of these behavioural shifts and their consequ

244 ual orientation or gender identity, although the causes of these brain/behavior relationships are unc

245 ons in Eurasian seasonal cooling, we examine the causes of these changes.

246 investigation and consequently knowledge on the causes of these deaths in low- and middle-income cou

247 h autoimmune cytopenias (AICs; CVID+AIC) and the causes of these derangements.

248 The causes of these differences are discussed with refer

249 The causes of these islands remain unclear, however, wit

250 which each of these relationships occur nor the causes of these relationships are fully understood.

251 Although the causes of these strandings are unknown, a number of

252 Although the cause of this conformational change remains elusive,

253 Here, we reveal the cause of this deafness using a mouse model engineere

254 pecific defect in centriole duplication, but the cause of this deficit remains unknown.

255 pproaches and genome sequencing, we identify the cause of this difference as a nonsense mutation in t

256 Considerations for the cause of this disease emphasise an interaction of ch

257 imary cells from these patients to determine the cause of this hyperprogression.

258 toward groups linked to the perpetrators as the cause of this increase.

259 The cause of this injury is uncertain but is suspected t

260 The cause of this lethality is unknown.

261 ctor T cell malfunction in tumours(1-4), but the cause of this link is unknown.

262 cing were used to identify ANDV infection as the cause of this outbreak of hantavirus pulmonary syndr

263 ial organisation at egg chamber termini, but the cause of this phenotype remains unclear.

264 r conductance, it is essential to understand the cause of this remarkably pervasive pattern.

265 Searching for the cause of this response, we evaluate the changes in t

266 atens current treatment recommendations, but the cause of this rise is not well understood.

267 The cause of this selective loss of beta cells needs to

268 The cause of this sex difference has yet to be elucidate

269 We show here that the cause of this softening is the compressibility of pl

270 Impaired immune cell functions may be the cause of this susceptibility, but detailed mechanism

271 actors that are likely to be contributing to the cause of this syndrome and consider how they might b

272 fespans tend to host more zoonoses; however, the causes of this association remain poorly understood

273 To explore the causes of this bimodal seismicity, we developed a tw

274 The causes of this increase are not well established.

275 is a major risk factor for AKI and we review the causes of this increased risk.

276 The causes of this major deficiency and consequences the

277 The causes of this paradoxical observation - that uncons

278 rmously in mortality risk and longevity, but the causes of this variation remain poorly understood.

279 of a gain-of-function mutation in CACNA1C as the cause of Timothy syndrome, a rare disorder character

280 We identify empirical priorities for testing the cause of tip-to-base conduit widening and underscore

281 mpurities from the precipitant could also be the cause of toxicity of Invitrogen method-based exosoma

282 ry change has been rigorously established as the cause of trait exaggeration.

283 The causes of treatment resistance are unknown, but it i

284 mal models will provide further insight into the causes of trigeminal neuralgia and its pathophysiolo

285 enterica serovar Typhi (Salmonella Typhi) is the cause of typhoid fever and a human host-restricted o

286 However, the causes of ubiquitous and dramatic intra-arc variatio

287 Current understanding of the causes of under-5 childhood deaths in low- and middl

288 vention Surveillance (CHAMPS) Network tracks the causes of under-5 mortality and stillbirths at sites

289 e 9 inherited arrhythmia syndrome (LQT9) and the cause of underlying action potential duration prolon

290 When addressing the cause of underlying disease, the management of cardi

291 Understanding the causes of vaccine failure is important for predictin

292 The cause of variability in the outcome remains unclear,

293 depends on several factors and in this study the cause of variation in bioavailability and content of

294 e tested five non-exclusive hypotheses about the causes of variation in multiple mating and its benef

295 Here, we review the causes of variations in observed and modelled histor

296 Diagnostic tools to establish the cause of viremia are urgently needed to accelerate c

297 These data show that the cause of virus resistance is 2-fold; ISG15 deficienc

298 pathy is a heterogeneous group of conditions the cause of which is largely unknown.

299 bovine sperm results in reduced conception, the causes of which are only partly understood.

300 While the cause of WS remains inconclusive, this study demonst