ライフサイエンスコーパス: the observed

1 and the estimated risk closely approximated the observed 10-year risk (Lin concordance 0.962).

2 Extensive droughts are consistent with the observed 20th-century trend toward positive SAM anom

3 chemical evidence support our diagnosis: (1) the observed (6.93 eV) and calculated (CCSD(T)/pVQZ) adi

4 hondrial activity or GABA signaling corrects the observed abnormalities.

5 t of intrinsic OER activity, suggesting that the observed activity increase is dominantly a result of

6 same experiment, it has been unclear whether the observed activity reflects how much attention is bei

7 e new knowledge regarding the preferences of the observed actor.

8 R, 0.67; 95% CI, 0.43 to 1.04; P = .07), and the observed adverse events were consistent with the kno

9 Although a physiological role of the observed alternative pose remains to be validated, o

10 We therefore analyzed the observed amino acid changes phenotypically in a dive

11 ients with PCH3 could be involved in many of the observed anatomical and behavioral symptoms, and tha

12 y one hour in spring and autumn by comparing the observed and expected diagnosis rates after DST shif

13 ining set, estimate the relationship between the observed and predicted outcomes in the testing set,

14 d representation of the relationship between the observed and predicted outcomes.

15 propose that substantial UDB contributes to the observed antiarrhythmic efficacy of GS-967 and elecl

16 The root cause of the observed antiinflammatory phenotype in stimulated Th

17 Moreover, our results suggested that the observed antioxidant protection involve both redox a

18 l age at onset (RAO): The difference between the observed AO and the AO predicted on the basis of the

19 Bioinformatic comparisons of the observed APOBEC3A mutation signature in murine tumor

20 tional theory calculations are performed and the observed appealing catalytic performance is correlat

21 d were the reaction pathways responsible for the observed aroma changes during the UHT treatment.

22 The observed association between the delta(13) C and WUE

23 founding accounted for some, but not all, of the observed association.

24 aternal and fetal genetic effects underlying the observed associations between maternal phenotypes an

25 We validated a subset of the observed associations in an independent case-control

26 , revealing the causal genes responsible for the observed associations is challenging.

27 The observed associations remained after excluding incid

28 The observed asymmetry, very small in the unperturbed st

29 ripening providing a possible mechanism for the observed auxin effects.

30 ectra and characteristic frequencies outside the observed band.

31 The observed behavior of climatic complexity could be ex

32 lysis revealed gene clusters associated with the observed behavioral responses, mostly related to the

33 d to develop a mechanistic understanding for the observed behaviors, predominantly focusing on the ce

34 s a quantitative mechanistic explanation for the observed benefits of SGLT2i in HF-rEF.

35 , no differences were found, suggesting that the observed beta patterns may represent an aspect of hi

36 f three species and show that within many of the observed bicliques the neurons share statistically s

37 A prototropic shift leads to the observed bicyclic products in what can be viewed as

38 The observed binding modes appear to anchor the Dsl1 com

39 ate and in solution, showing a dependence of the observed binding strength on the shape of the guest

40 The observed biochemical changes can explain the dominan

41 Furthermore, the observed carbamazepine-mediated Wnt signaling inhibi

42 of flower color is consistent with not only the observed carotenoid accumulation pattern, but also w

43 r phenotype, measured by CAGE, recapitulated the observed cellular phenotypes while providing additio

44 er in their cellular architecture and relate the observed cellular states to established GSC markers.

45 ion and investigation of potential causes of the observed changes are needed, indicate that epilepsy-

46 on record, this analysis also indicates that the observed changes are, at least to some extent, attri

47 Individual gene knockouts mirrored many of the observed changes in an overlapping fashion between k

48 ) T cells in the spleen and was required for the observed changes in both T cell and myeloid populati

49 to hot carriers, are the main contributor to the observed changes in interfacial reactivity upon illu

50 ly localize in the red pulp, suggesting that the observed changes in lipid composition are due to dif

51 To explore the underlying components of the observed changes, we divide bee toxic load into exte

52 The observed clinical effect size was within one standar

53 The observed cluster substructures are more efficient le

54 inear regression model in which we regressed the observed CNS on predictor variables: age, sex, arriv

55 models to predict mortality was highest when the observed CNS was included (C statistic, 0.82 [95% CI

56 ake them prime candidates to explain much of the observed coallergy among peanuts, tree nuts, and ses

57 ethod allows the assignment of the nature of the observed coherence as vibrational or electronic.

58 atellite formation, resulting in a change in the observed color.

59 lasmid abundance over time explained more of the observed community dynamics than phages.

60 mune diseases, but the mechanisms underlying the observed comorbidities are unknown.

61 The observed constant free to bound forms ratio showed t

62 tures or model assumptions are necessary for the observed continual evolution to emerge, and whether

63 The observed correlation suggest that rectal gonorrhea i

64 To shed light on the observed correlation, the framework confined environ

65 The observed CusS mobilization upon stimulation and its

66 he predicted PK profiles and parameters with the observed data from published rat and human data foll

67 effect, but a six-week delay in snow-onset (the observed data range) was estimated to increase late

68 a conventional Kaplan-Meier curve applied to the observed data was compared with that of an inverse p

69 tial contribution of leaky vaccine effect to the observed decline in mVE.

70 The observed decline in species diversity under simultan

71 The model accurately reproduced the observed decline of HBsAg and HDV, which was simulta

72 hyperproliferation is the primary cause for the observed defects causing insufficient alignment of t

73 interaction with actin, which could explain the observed delays in the onset of relaxation.

74 The observed developmental trajectory of affected connec

75 n and activity, which mostly correlated with the observed deviations from Arrhenius-type behavior, wi

76 The observed diastereoselectivities correlate with the c

77 density functional theory calculations, and the observed diastereoselectivity was rationalized in th

78 The observed difference between women and men of 146 phe

79 l content (non-stomatal limitation), whereas the observed differences between water conditions were m

80 The observed differences in A. cahirinus sleep architect

81 Consistent with the observed differences in activity, the chimeric m2/m1

82 in the past, the finest molecular details of the observed differences in interactions between Hp and

83 computational studies, we have rationalized the observed differences in reactivities and designed mu

84 the NO donor sodium nitroprusside eliminated the observed differences.

85 ded to understand the clinical importance of the observed differences.

86 The observed directional CSF flow can be explained by na

87 ng the specific source types responsible for the observed discrepancies.

88 are access and exposure factors may underlie the observed disparities more than susceptibility due to

89 Only the R3m model was able to account for the observed displacement of titanium in the [111] direc

90 king backward from the experimental results, the observed distribution appears inconsistent with a Ga

91 The observed distribution is a truncated power law.

92 een a hypothetical Gaussian distribution and the observed distribution of test results after Box-Cox-

93 etrical distribution and a truncated part of the observed distribution, specifically, the Kolmogorov-

94 clude by discussing potential mechanisms for the observed diurnal variation in resting brain activity

95 the developmental mechanisms responsible for the observed diversity of pollen and spore walls, the pr

96 condition also showed better agreement with the observed DO fluxes than the simulated profiles with

97 ibed a microRNA network which contributes to the observed down- and upregulation of proliferative and

98 However, even during non-stress periods, the observed dynamics for all taxa were unable to mainta

99 and between Western blotting experiments and the observed effect confirmed with a complementary or or

100 We suggest that the observed effect is instead determined by the dominat

101 However, the observed effect of those compounds likely resulted f

102 Approximately one-tenth of the observed effect of WHR was mediated by SBP for ische

103 dentified six compounds could explain 79% of the observed effect, with albendazole and paroxetine as

104 The observed effectiveness is consistent with efficacy i

105 skeletal muscle cells, and evaluated whether the observed effects are relevant in humans.

106 ons to the fecal microbiota may help explain the observed effects of asymptomatic infections on growt

107 Finally, we found that the observed effects of dynamic chloride on neuronal out

108 rations of the gut microbiome contributed to the observed effects.

109 d from schistosome eggs were responsible for the observed effects.

110 These data are consistent with the observed efficacy of bezlotoxumab, and lack of effic

111 -based field-effect transistors reveals that the observed electrical conductivity (sigma(RT) <= 1.3 x

112 nsfer and the microbial taxa associated with the observed electroactivity are fundamental to oxygen-r

113 ve relationship between KCNQ1 antibodies and the observed electrophysiological effects has never been

114 and free energy calculations to rationalize the observed elusiveness of the third form of iproniazid

115 ant K562 cells, indicating the generality of the observed EMD effects.

116 ron-deficient pyridone ligand is crucial for the observed enantioselectivity.

117 With real human sweat the observed energy and power densities are 0.25 Wh kg(-

118 The observed enhancement in sensor performance is believ

119 We propose that the observed epigenetic alterations reflect distinct dif

120 The photochemical analysis suggests that the observed expansion is due to internal pressure exert

121 We obtain a comprehensive explanation of the observed experimental signatures from a model of pol

122 The observed features are discussed with respect to the

123 The observed features imply global transfer of impact-re

124 r toward fighters was strongly influenced by the observed fight; bystanders were less aggressive towa

125 The observed [Formula: see text] has a positive correlat

126 ctural locations contribute significantly to the observed [Formula: see text] values in cell-based as

127 n UM patients were significantly higher than the observed frequencies in noncancer controls (PALB2: P

128 of corticostriatal synapses, indicating that the observed functional defects are not due to morpholog

129 stability within these regions contribute to the observed functional differences in Drosophila EMB an

130 The observed gender gap in collections was highly persis

131 that ILRUN may be the casual gene underlying the observed genetic associations with plasma lipids at

132 pproach to mutation rate estimation based on the observed genetic variation and the expected site fre

133 g their Golgi residence times, we found that the observed Golgi localization of O-glycan-deficient ca

134 on of several secreted factors that underlie the observed guidance defects and proteins that promote

135 indicative of an immune-based mechanism for the observed hepatic enzyme elevations.

136 have yielded only limited insights, leaving the observed heritability of HF largely unexplained.

137 This finding indicates that the observed high lead fractions likely consist of mostl

138 A dual-ligand system is crucial for the observed high reactivity and site selectivity.

139 Consistent with the observed higher OS in patients with TERT-low/non-ALT

140 The observed higher tolerance was positively linked to m

141 more active, which is counterintuitive with the observed higher virulence of the 2016-17 outbreak vi

142 The observed homochirality in all life on Earth, that is

143 Once clinical data are available, the observed human PK are compared with predictions, pro

144 water molecules does not significantly alter the observed hydrogen-bond topologies.

145 , and the uncertain clinical significance of the observed immunological effects.

146 vels) and primary production can account for the observed increase in fish production, while changes

147 OC concentration was less than expected from the observed increase in radiocarbon content from those

148 al biomass and necromass that translate into the observed increase in SOC.

149 oybeans were not found to be responsible for the observed increase of insecticidal activity.

150 er, different environmental cues may lead to the observed increase of Vdelta1(+) and Vdelta3(+) TRD s

151 ere are no safe levels of metals in infants, the observed increases in cord blood lead and cadmium re

152 models of social preference can account for the observed individual differences in reciprocity motiv

153 The observed inhibition of FGF signaling was accompanied

154 To confirm an OR mechanism for the observed inhibition, we performed single-cell transc

155 BMP type 1 receptor binding site similar to the observed interactions in RGM-BMP2 complexes.

156 The observed interactive effects of temperature, oxygen

157 The observed interdependence of these indicators and cor

158 d account for some, but probably not all, of the observed intraseasonal decreases in mVE.

159 noclonal antibodies, this study investigates the observed intrinsic protein fluorescence emission spe

160 more complex kinetic model that accounts for the observed isotope exchange and catalytic effect of Fe

161 anomalous properties of GW170817, including the observed kilonova emission from that event.

162 g formate oxidation, significantly affecting the observed kinetic behavior and providing three differ

163 rocessivity and/or collaboration can produce the observed kinetic correlations.

164 rature or pH can have a pronounced effect on the observed kinetics that can manifest in significant r

165 se soluble fractions could partially explain the observed lack of antimicrobial activity.

166 The observed lattice is composed of three antiferromagne

167 ns suggest that the anionic lipid stabilizes the observed ligand-bound structure.

168 The observed limit of detection was more than 30-fold be

169 Finally, we reproduce the observed lineage dynamics by simulations.

170 The observed long-range intra-generational correlations

171 imes in major U.S. cities, which aligns with the observed long-term changes in urban-rural gradient o

172 The model explains the observed low dip angle of the slab and predicts a de

173 re in green mEos4b thus largely accounts for the observed lower switching contrast as compared to tha

174 teria and phages are the key to formation of the observed lysis pattern.

175 The neuronal model accurately recapitulated the observed magnetoencephalographic data.

176 At month 22, the observed mean BCVA change from baseline was -4.6 Ear

177 The observed mechanism seems to be a safeguard against t

178 However, the observed metabolic and hemodynamic changes were mode

179 xamination of drug metabolites suggests that the observed metabolic gradients are pharmacologically r

180 tify the AGO1-mediated mechanisms underlying the observed metabolic phenotype of EC-AGO1-KO.

181 lucidated the cellular mechanisms underlying the observed metabolic phenotypes.

182 al overall survival were calculated based on the observed MFS and OS.

183 The observed microbiome alternations could be related to

184 ssDNA, the predicted mobilities are close to the observed mobilities at ionic strengths <=0.01 M if t

185 nts and simulations, it is demonstrated that the observed morphological changes are caused by symmetr

186 atch the actual object weight as revealed by the observed movement kinematics.

187 By fitting a stochastic model to the observed mRNA distributions, we show that the transi

188 ponses to stimuli and high centrality within the observed network.

189 rplay between the local network of atoms and the observed NMR signals.

190 Here, we report that all the observed NPF events from the Arctic Ocean 2018 exped

191 indicator for the size of the epidemic, but the observed number of deaths represents only a minority

192 p-sample interactions is introduced to model the observed opto-mechanical damping.

193 The observed order-of-magnitude difference in (-)ESI eff

194 omal interactions are necessary to establish the observed organization.

195 ment and redox potential; this gives rise to the observed overlap in Mn and O redox couples and revea

196 d with human mediated dispersal resulting in the observed panmictic population.

197 Here we show that the observed part of Phaethon does not exhibit the 3-um

198 It is possible that the observed part of Phaethon was originally hydrated an

199 ible to control for) may have contributed to the observed pattern.

200 The observed patterns are indicative of an adaptive seas

201 The observed patterns of increases in both TLA and E ind

202 ing climate models do not accurately capture the observed patterns of ocean warming, with a large spr

203 ted with photosynthate transport in yielding the observed patterns of soil CO(2) efflux being out of

204 aring their theoretical isotopic signal with the observed peaks.

205 radients in local physiology, contributed to the observed phase shifts.

206 disappears at the dilution concentration for the observed phase transition equivalent to 62% (v/v).

207 This loss may be associated with the observed phenotype change but the mechanism remains

208 ale germline, quantitative studies that link the observed phenotypes to underlying error mechanisms a

209 ions are not always concordant with those in the observed phenotypes, suggesting that the PRS differe

210 ome-scale metabolic models representative of the observed phenotypes.

211 effect size that are thought to account for the observed phenotypes.

212 The observed phenotypic patterns are likely mediated by

213 A strong metabolic correlation exists with the observed phenotypic traits.

214 by SU5402 impacts a significant fraction of the observed phosphoproteome of these cells.

215 ivation), thus providing one explanation for the observed photothermal activity.

216 The metabolic perturbations corroborate the observed physiological responses.

217 that the neutral density required to produce the observed pickup ion fluxes is similar to typical exo

218 These effects could explain the observed PIP2 enrichment in HIV-1.

219 We show that parameter modulation impacts the observed points by introducing directionality in the

220 rpretable effect of parametric modulation on the observed points.

221 pment are hypothesized to be responsible for the observed population distributions of disease.

222 s different technology options CLEAR matches the observed (post-diction) constant rate-of-growth, and

223 The observed precision of isotope ratios is limited by t

224 geometry is the main factor contributing to the observed pressure gain.

225 4-14.2) represent a significant decline from the observed prevalence in R1 (19.4%, 95% CI: 16.8-22.3)

226 ubstitution, implicating this interaction in the observed processing phenotype.

227 complete cleavage of the N(2) triple bond in the observed product).

228 petition between subsequent pathways to form the observed products.

229 rensis when compared with B. anthracis while the observed profiles of each of the two F. tularensis a

230 tegories, divided into 3 stages that reflect the observed progression pattern, plus a miscellaneous c

231 tively, provided insight into the origins of the observed protections.

232 The observed QPI characteristics exactly match with theo

233 ulae for the effect of finite sample size on the observed r(2) values.

234 a new empirical formula for the variance of the observed r(2), equals to 2E[r(2)](1 - E[r(2)])/n, wh

235 Numerical simulations indicate that the observed rapid cross-frontal mixing occurs via shear

236 In addition, the observed rate constant of EBS increased in the prese

237 by other fates is sufficient to account for the observed rate of return to normal centriole number.

238 The observed rates of hypoglycemia with severity of leve

239 The observed reaction kinetics for loss of THC on glass

240 id-base (HSAB) theory is advanced to explain the observed reactivity trends.

241 other indicator/Au-Pd NP systems tested, (2) the observed redox chemistry with H(2) followed well-und

242 Transcriptional analysis suggests that the observed reduction in colonization may be caused, in

243 tochromes, cytochrome c (1) and cytochrome c The observed reduction in the steady-state abundance of

244 1R expression conclusively demonstrated that the observed reduction in tracer uptake directly correla

245 an individual antimicrobial agents, underlie the observed reductions in brain amyloidosis.

246 The observed regioselectivity of the ortho-cyclization o

247 le interaction rules can effectively explain the observed regularity and heterogeneity in scaling beh

248 bal reductions in TBV statistically mediated the observed relationship between institutionalization a

249 in treatment (1 g monodose), consistent with the observed relative resistance of L. iners to azithrom

250 The observed relevance of open conformations resolves th

251 temperature eliminate phononic mechanism of the observed renormalization and identify the onset of s

252 The observed scaling laws are altered in mice receiving

253 The observed SDS-PAGE bands did not show any evidence of

254 Model results suggest that the observed seasonal seroprevalence dynamics can be bes

255 10 terrestrial biosphere models to reproduce the observed sensitivity of ecosystem productivity to ra

256 findings provide a possible explanation for the observed sex biases in COVID-19, and provide an impo

257 The observed shallow distance dependence for tyrosine ox

258 rsity of spatial signaling states to explain the observed shapes.

259 The model analysis of the observed size distribution evolution shows that liqu

260 outweighed background mortality for most of the observed size range.

261 stimates of epidemic parameters suggest that the observed slow growth rates in the 14th century are i

262 Despite the observed spatial state and frequency invariance, FC

263 sical model of the system that recapitulates the observed spindle-cortex interactions.

264 ring temperatures did contribute strongly to the observed spring migration advancements over the 55-y

265 a fluctuation scaling law as a benchmark for the observed standard deviations.

266 to capture the reaction kinetics and explain the observed stereochemical distributions.

267 between cis-trans regulatory changes explain the observed sterility.

268 l composition are suggested to contribute to the observed stiffness gradients.

269 bursts occur too infrequently to account for the observed stopping behavior.

270 The observed strong dependence of (1)O(2) sensitization

271 etween them, and the effects of mutations on the observed structural ensembles.

272 The stability of the observed structures depends on the geometrical match

273 The observed subgingival bacterial patterns in these eld

274 implications of these results in explaining the observed superior effects of combination treatment o

275 The observed symmetries of the anomalous Josephson effec

276 tions ranging from r = 0.35 to r = 0.51 with the observed symptom scores.

277 The observed targeting of tumor lesions suggests this ma

278 to non-planar conformational transition) in the observed thermochromic behavior of polythiophene but

279 Model simulations matched the observed timing and dynamics of wood formation.

280 types and discuss potential explanations for the observed tissue specificity.

281 dies, organotin cations and ammonia dominate the observed toxicity according to toxic unit (TU) asses

282 successfully validated (R(2) = 0.92) against the observed tracheid enlargement time course.

283 , we identified several candidate drivers of the observed transcriptional response to CYP2J2 silencin

284 llular mutant phenotypes are consistent with the observed transcriptome misregulation, as cht7 cells

285 and electrophoretic drift, it is shown that the observed trend is the result of two competing mechan

286 Common species drove the observed trends, and both specialist and generalist

287 degree of nonisochronicity was required for the observed tuning behavior in the coherence of autonom

288 We found that the observed vaccination behavior in the Israeli OPV cam

289 s-in some cases, explaining more than 50% of the observed variance.

290 k of skin cancer, and there was diversity in the observed variants across sample populations.

291 Among a larger sample of 95 countries, the observed variation in COVID-19 CFRs is 13 times larg

292 peptide binding motifs, which could explain the observed variations in peptide binding preferences a

293 When comparing institutions, the observed-versus-expected rate for achieving TO varie

294 We used fixed-effects models to compare the observed volume as well as calorie and sugar content

295 us providing a unified theoretical basis for the observed wavelength dependence of absorption in gree

296 nt initiation and leptin dose do not predict the observed weight loss in lean individuals suggesting

297 mpathetic nervous system partially abolished the observed wild-type blood flow decrease but not the s

298 life history and population size can explain the observed X:A diversity ratios in extant human popula

299 They released a dataset that contained the observed yields for 294,128 corn hybrids through the

300 active species appears to be responsible for the observed Z-selectivity.