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1 ar function and serve as primary targets for therapeutic intervention.
2 es, making glucagon an attractive target for therapeutic intervention.
3 sis of pemphigus and offer novel targets for therapeutic intervention.
4 sequence that could be potential targets for therapeutic intervention.
5 rganisms, making this a promising target for therapeutic intervention.
6 COVID-19, and NETs may represent targets for therapeutic intervention.
7 s are novel potential anticancer targets for therapeutic intervention.
8 potential of targeting senescent cells as a therapeutic intervention.
9 omain, and p47phox is a potential target for therapeutic intervention.
10 uch biases can serve as specific targets for therapeutic intervention.
11 te biomarkers for patient stratification and therapeutic intervention.
12 diseases, and identify potential targets for therapeutic intervention.
13 cells, and represents a molecular target for therapeutic intervention.
14 sm and highlights a potential new target for therapeutic intervention.
15 ther by native factors within the cell or by therapeutic intervention.
16 ary prostate tumors as potential targets for therapeutic intervention.
17 enesis and offer new prospective targets for therapeutic intervention.
18 e may provide the most effective setting for therapeutic intervention.
19 first compelling axonal-specific target for therapeutic intervention.
20 and sepsis and consider future direction for therapeutic intervention.
21 y and inflammation that might be amenable to therapeutic intervention.
22 rs including the complex tumor ecosystem and therapeutic intervention.
23 ol for future studies of PD pathogenesis and therapeutic intervention.
24 ext, review progress identifying targets for therapeutic intervention.
25 vo has the potential to identify targets for therapeutic intervention.
26 for identifying novel targets for improving therapeutic intervention.
27 ore promising candidates for antinociceptive therapeutic intervention.
28 ies possess that render them recalcitrant to therapeutic intervention.
29 and PIH and highlight promising targets for therapeutic intervention.
30 plexes promising targets for region-specific therapeutic intervention.
31 e mechanisms that offer distinct targets for therapeutic intervention.
32 ptomatic phase are limited, precluding early therapeutic intervention.
33 st decade has revealed new opportunities for therapeutic intervention.
34 nt response and reveal potential targets for therapeutic intervention.
35 n of SBCE is the lack of any possible direct therapeutic intervention.
36 making this pathway an attractive target for therapeutic intervention.
37 lele with a later disease onset, amenable to therapeutic intervention.
38 ng transformative opportunities for targeted therapeutic intervention.
39 capsid assembly is an attractive target for therapeutic intervention.
40 lograft function, and outcome independent of therapeutic intervention.
41 ess but also exposes a vulnerable target for therapeutic intervention.
42 sis and point towards additional avenues for therapeutic intervention.
43 n insight that could be exploited for future therapeutic intervention.
44 yield next generation molecular targets for therapeutic intervention.
45 candidate circuit and molecular pathways for therapeutic intervention.
46 lopment of precision medicine approaches for therapeutic intervention.
47 ogression, and tracking the effectiveness of therapeutic intervention.
48 ATG9A may be a rational strategy for future therapeutic intervention.
49 vation creates an attractive opportunity for therapeutic intervention.
50 ment of kidney fibrosis with a potential for therapeutic intervention.
51 th promotion, and may have the potential for therapeutic intervention.
52 eonine kinase ALK2 as a potential target for therapeutic intervention.
53 ent has identified new targets within it for therapeutic intervention.
54 c free thiols are amenable to nutritional or therapeutic intervention.
55 risk of common diseases responsive to early therapeutic intervention.
56 factors are being considered as targets for therapeutic intervention.
57 pathogenesis and to identify new targets for therapeutic intervention.
58 ungal bloodstream infections for pre-emptive therapeutic intervention.
59 ulation imbalance and identify potential for therapeutic intervention.
60 making this pathway an attractive target for therapeutic intervention.
61 pects for disease-subtype classification and therapeutic intervention.
62 se progression and decreases with successful therapeutic intervention.
63 cally relevant target with opportunities for therapeutic intervention.
64 gical effects of SHBG or develop targets for therapeutic intervention.
65 oteolytic activity represents a key node for therapeutic intervention.
66 ll-cell interfaces present opportunities for therapeutic intervention.
67 ablasts, and serve as a potential target for therapeutic intervention.
68 ic diagnosis and identifying novel points of therapeutic intervention.
69 c molecular mechanisms and the potential for therapeutic intervention.
70 ew mechanisms and accompanying routes toward therapeutic intervention.
71 ted pathways represent potential targets for therapeutic intervention.
72 emia and biopsy-proven BKPyVAN with need for therapeutic intervention.
73 lular residue that could become a target for therapeutic intervention.
74 urther investigated as potential targets for therapeutic intervention.
75 on and identify TNFR2pos Treg as targets for therapeutic intervention.
76 facilitate closed-loop neurostimulation for therapeutic interventions.
77 ted an urgent demand for new, more effective therapeutic interventions.
78 kes it a feasible target for preventative or therapeutic interventions.
79 tient populations to increase the success of therapeutic interventions.
80 ith implications for developing sex-specific therapeutic interventions.
81 at interest for both diagnostic and adjuvant therapeutic interventions.
82 efinition, difficult to treat using standard therapeutic interventions.
83 have informed potential avenues for rational therapeutic interventions.
84 he disease and proposing rationally designed therapeutic interventions.
85 tion; and provides potential new targets for therapeutic interventions.
86 ed in ZIKV replication may guide efficacious therapeutic interventions.
87 diagnostic biomarkers as well as targets for therapeutic interventions.
88 ould provide a molecular basis for potential therapeutic interventions.
89 lthy guts, and are attractive candidates for therapeutic interventions.
90 tive and isolation resources and allow rapid therapeutic interventions.
91 d immune signaling is a potential target for therapeutic interventions.
92 es they have gained attention as targets for therapeutic interventions.
93 plex mechanism will help uncover targets for therapeutic interventions.
94 e potential opportunities and challenges for therapeutic interventions.
95 rin inflammasome, which can be harnessed for therapeutic interventions.
96 r of the lesions and may serve as a guide to therapeutic interventions.
97 h mild and lethal COVID-19 and for assessing therapeutic interventions.
98 HCC creates more opportunities for curative therapeutic interventions.
99 identified novel targets with potential for therapeutic interventions.
100 r investigate RLN regeneration and potential therapeutic interventions.
101 editation has been integrated into different therapeutic interventions.
102 y when CT or MRI are inconclusive or to plan therapeutic interventions.
103 ists in neuroscience research and envisioned therapeutic interventions.
104 in the CNS, opening novel opportunities for therapeutic interventions.
105 rk dynamics and identify potential points of therapeutic interventions.
106 or preventing mania and for developing novel therapeutic interventions.
107 y effective, highlighting the need for novel therapeutic interventions.
108 atients might therefore require personalized therapeutic interventions.
109 evaluate mechanisms of Tau transfer and find therapeutic interventions.
110 l be important for the development of future therapeutic interventions.
111 in the context of the on-going hunt for new therapeutic interventions.
112 ding a framework for improved diagnostic and therapeutic interventions.
113 er insight into potential future targets for therapeutic interventions.
114 notypic heterogeneity and offer a target for therapeutic interventions.
115 plications for selection of GBA carriers for therapeutic interventions.
116 the implications on disease development and therapeutic interventions.
117 d by host immune responses as well as during therapeutic interventions.
118 ding cancer cell biology and its response to therapeutic interventions.
119 isease process will guide development of new therapeutic interventions.
120 ity and mortality and is in need of improved therapeutic interventions.
121 ion and hold considerable promise for use in therapeutic interventions.
122 amic process of intestinal fibrosis and test therapeutic interventions.
123 ransplantation (FMT), are being developed as therapeutic interventions.
124 olism, making it a candidate of interest for therapeutic interventions.
125 CC representing candidates for prognosis and therapeutic interventions.
126 nals and development of resistance following therapeutic interventions.
127 creasing yearly and there are no efficacious therapeutic interventions.
128 food allergy and hence provide a window for therapeutic interventions.
129 hese disorders may also permit more targeted therapeutic interventions.
130 prostate cancer and is a crucial target for therapeutic interventions.
131 ation and aid in delivery of future tailored therapeutic interventions.
132 with BPD features, and to inform and assess therapeutic interventions.
133 issues related to adoption and adherence of therapeutic interventions.
134 h SARS-CoV-2, requires urgent development of therapeutic interventions.
135 demands while escaping immunosurveillance or therapeutic interventions.
136 and could potentially be used as targets in therapeutic interventions.
137 O(2) and its effectors could be targeted for therapeutic interventions.
138 very is required to inform research into new therapeutic interventions.
139 ng within and between tissues and can enable therapeutic interventions.
140 ns provides a potential mechanism for future therapeutic interventions.
141 fy a potential cellular target for exploring therapeutic interventions.
142 yelination, thus presenting a new target for therapeutic interventions.
143 nd translation of new medical treatments and therapeutics interventions affecting pelvic organs, incl
146 prove useful for evaluating prophylactic or therapeutic interventions against clade C HIV-1.IMPORTAN
147 g this activity may serve as an approach for therapeutic interventions against existing and emerging
148 umours and inflammatory diseases will enable therapeutic intervention aimed at resetting the bioavail
149 stage transitions are important targets for therapeutic intervention aimed at thwarting parasite tra
150 signaling and providing proof-of-concept for therapeutic interventions aimed at ameliorating OMCDi dy
151 sing systems are promising targets for human therapeutic intervention and developing stress-resilient
152 ard to duration of BKPyV-DNAemia and need of therapeutic intervention and diagnosis of proven BKPyVAN
153 mechanisms of COVID-19, identify points for therapeutic intervention and improve vaccine design and
154 ntibodies represent promising candidates for therapeutic intervention and reveal a target for the rat
155 of cocaine seeking strongly supports EE as a therapeutic intervention and suggests EE is capable of p
156 This study identifies several targets for therapeutic interventions and may help bridge the gap in
157 ory marker REG3alpha may be used to evaluate therapeutic interventions and predict non-AIDS comorbidi
158 nical Working Group of Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV), a public
159 ediated-microvascular changes, evaluation of therapeutic interventions, and eventual reversal of thes
160 d tracking glucose trends over time, optimal therapeutic interventions, and improving the life of dia
161 nation of knowledge, limits understanding of therapeutic interventions, and may ultimately harm patie
162 studies into osteoarthritis patient-specific therapeutic interventions, and thereby improve the healt
163 d standard for testing the efficacy of novel therapeutic interventions, and typically report the aver
164 outcomes associated with different timing of therapeutic intervention are contributing to our underst
166 To date, there is no licensed vaccine or therapeutic intervention available for the fight against
167 l disability in DS signal a new era in which therapeutic interventions based on knowledge of the mole
168 ect nucleic acids are attractive targets for therapeutic intervention because of their diverse roles
169 f Fabry nephropathy and indicates a need for therapeutic intervention before critical podocyte loss o
170 ems happen, thus opening the possibility for therapeutic interventions before the occurrence of sympt
171 orders, the underlying disease or associated therapeutic interventions can cause hypoxia, cytotoxicit
172 n and indicate that immune-based targets for therapeutic interventions constitute a promising treatme
173 Despite important advances in diagnostic and therapeutic interventions, data derived from registries
174 mentally new steps that could be targeted by therapeutic interventions designed to combat protein mis
175 and to allow for new ways of thinking about therapeutic interventions, diagnostic biomarkers, and th
177 tant cells, suggesting the potential for new therapeutic interventions, directed against evolving res
178 's disease (HD) and as such are a target for therapeutic intervention, especially for the treatment o
179 ly target a particular multimeric lectin for therapeutic interventions, especially under the challeng
182 sults highlight that ICV-ERT is an effective therapeutic intervention for managing GM1 gangliosidosis
184 e Sirt1-Nox4 axis in muscles is an effective therapeutic intervention for mitigating pancreatic cance
185 locybin is showing considerable promise as a therapeutic intervention for neuropsychiatric disorders
186 ex (H-reflex) is a non-invasive and targeted therapeutic intervention for patients with movement diso
189 bility of DS and to evaluate the efficacy of therapeutic interventions for breathing and sleep anomal
190 heckpoints and could be channeled to develop therapeutic interventions for cilia-associated disorders
191 1 is a potential target for preventative and therapeutic interventions for disease caused by NTHi.
192 erstanding of this area will help us develop therapeutic interventions for diseases where dysregulate
193 OXO1 and present information useful both for therapeutic interventions for muscle atrophy and for fur
195 re merits further study as a metric to guide therapeutic interventions for patients with bacterial pn
196 ss the therapeutic efficacy of new promising therapeutic interventions for PH, and could serve as a c
197 ylation, therefore, is a promising target of therapeutic interventions for presently incurable forms
199 ghts into targets for the development of new therapeutic interventions for treating EBV-associated ly
201 -2 (ALK2) constitutes a potential target for therapeutic intervention given its dysregulation in the
202 ease progression, while the discovery of new therapeutic interventions has been disappointingly unsuc
203 ribes 5 stages of evolution for new surgical therapeutic interventions-Idea, Development, Exploration
204 ial of cells, which can be used for targeted therapeutic intervention.IMPORTANCE Merkel cell carcinom
205 channels are potential molecular targets for therapeutic intervention in a variety of pathological co
208 to use brain activity to directly control a therapeutic intervention in an interactive, closed-loop
212 This renders CRM1 an interesting target for therapeutic intervention in diverse cancer types and vir
214 he septin cytoskeleton as a potential future therapeutic intervention in human inflammatory and fibro
215 y additionally suggest potential targets for therapeutic intervention in inflammatory bowel disease.
217 ritic branching, and may define pathways for therapeutic intervention in neurodegenerative diseases.
218 y offer a unique disease modifying method of therapeutic intervention in neurodegenerative disorders.
220 RRs might prove useful for prediction and/or therapeutic intervention in OLT patients before transpla
222 gial nucleus may be a promising approach for therapeutic intervention in temporal lobe epilepsy.
223 r and suggest targeting MEK5 as an effective therapeutic intervention in the management of this disea
224 Thus, scRNA-seq analyses guided successful therapeutic intervention in the patient with refractory
225 tory B cell function and their potential for therapeutic intervention in the setting of solid cancers
226 tastasis, and provides potential targets for therapeutic intervention in this heterogeneous disease.
227 a biomarker allowing for time point specific therapeutic interventions in Alzheimer's disease patient
228 e could contribute to the development of new therapeutic interventions in cancer and autoimmunity.
229 , and suggests multiple regulatory nodes for therapeutic interventions in diseases that involve ferro
232 u aggregates providing a potential basis for therapeutic interventions in neurodegenerative proteinop
233 n of these pathways provides new avenues for therapeutic interventions in NSD2 dysregulated malignanc
234 molecular pathways are potential targets for therapeutic interventions in patients with severe COVID-
236 y ClpXP activity as an unforeseen target for therapeutic interventions in the large group of mitochon
237 ere provides new avenues to disease altering therapeutic interventions in the treatment of type 1 dia
239 te that RvD5-PLD2 are attractive targets for therapeutic interventions in vascular inflammation such
241 ssue types, under disease and in response to therapeutic interventions, it has common interactions th
242 gnaling, the developed nanobiomaterial-based therapeutic intervention may pave a new road for treatin
244 nform client-specific and cell-type-specific therapeutic intervention of Hsp90-mediated protein activ
245 ion signaling may present an opportunity for therapeutic intervention of metastatic spread in ovarian
247 ork for predicting the influence of specific therapeutic interventions on the state of the opiate-dep
248 n together, these define multiple targetable therapeutic interventions opportunities for GBC treatmen
249 ign or pathogenic, such that the appropriate therapeutic interventions or surveillance can be impleme
250 Metalloenzymes are attractive targets for therapeutic intervention owing to their central roles in
251 ge conundrum in cancer medicine, making most therapeutic interventions palliative rather than curativ
253 lecular mechanism for COVID-19 that provides therapeutic intervention points that can be addressed wi
254 ut the underlying mechanisms and efficacy of therapeutic interventions promoting neural plasticity in
255 ut the underlying mechanisms and efficacy of therapeutic interventions promoting this plasticity in p
256 rming population screening programs, guiding therapeutic interventions, refining risk for families at
260 ecule-targeted procedures, in which specific therapeutic interventions require specific diagnostic gu
261 ed by exercise can be used to guide targeted therapeutic interventions requires further investigation
262 r cells, representing a potential target for therapeutic intervention.See related commentary by Man e
263 which could potentially inform on timing of therapeutic interventions.See related article by Rockne
264 identify early-stage ALS biomarkers and for therapeutic intervention.SIGNIFICANCE STATEMENT At diagn
265 eration, opening up possibilities for future therapeutic intervention.SIGNIFICANCE STATEMENT Parkinso
266 by the microbiota to suppress FA and discuss therapeutic intervention strategies that act to recapitu
269 modalities for COVID-19 is a necessity, and therapeutic interventions such as heparin-binding peptid
270 PyVAN, who would benefit from individualized therapeutic interventions such as reduced immunosuppress
275 hin the salivary gland and a possibility for therapeutic intervention that can reverse the loss of fu
277 nts of relapse are unclear, and there are no therapeutic interventions that can prevent recurrent dis
278 ication, highlighting a potential target for therapeutic interventions that counter AdV infection.
280 patient risk stratification, and present the therapeutic interventions that may alter Abeta metabolis
281 plications of these approaches for potential therapeutic interventions that target viral infection an
282 s for functional metabolic imaging and novel therapeutic interventions that will be complementary to
283 of causal cell subpopulations may accelerate therapeutic intervention to achieve lifelong remission.
284 e genetic, creating an opportunity for early therapeutic intervention to delay or prevent disease.
285 lts identify a potential cellular target for therapeutic intervention to restore aberrant network act
287 identify early damage and facilitate prompt therapeutic intervention to slow the progression of mult
289 We then conclude by identifying potential therapeutic interventions to correct deficits in RBC-med
290 ce centrally mediated events and on possible therapeutic interventions to correct imbalances in this
291 revention combined with additional effective therapeutic interventions to limit myopia progression ar
292 ay aid the identification of new or existing therapeutic interventions to limit the progression of ea
293 genesis call for early life preventative and therapeutic interventions to promote respiratory health.
296 important experimentally and for developing therapeutic interventions to treat mitochondrial disease
297 nd targeting MLK3 could serve as a potential therapeutic intervention via increasing T cell cytotoxic
298 nically relevant treatment scenario in mice, therapeutic interventions were withheld until clear symp
299 research, as well as for the development of therapeutic interventions with enhanced translational po
300 of clinical trials pursuing microbiome-based therapeutic interventions, with the hope of expanding im