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1 nt immune cells with versatile functions for therapeutic purpose.
2 or preparation of phytochemical essences for therapeutic purpose.
3 delivery of non-viral genes into the CNS for therapeutic purpose.
4 ther application in pathogens diagnostic and therapeutic purpose.
5 elluride, have been heavily investigated for therapeutic purposes.
6 at could be used to design ACE2 variants for therapeutic purposes.
7 ent-dependent cytotoxicity, is desirable for therapeutic purposes.
8  of this disease vector for preventative and therapeutic purposes.
9 regation inhibitors for biotechnological and therapeutic purposes.
10 ity of rational manipulation of immunity for therapeutic purposes.
11 ilencing and/or expressing a desired RNA for therapeutic purposes.
12 foundation for development of activators for therapeutic purposes.
13 d TA as target candidates for diagnostic and therapeutic purposes.
14 hal interactions that could be exploited for therapeutic purposes.
15 t to study how V-ATPase can be modulated for therapeutic purposes.
16 tor, opening a possible drug design path for therapeutic purposes.
17 les for approaches to modify BMP9 levels for therapeutic purposes.
18 t in transplantation of human stem cells for therapeutic purposes.
19 lations of circulating cells for research or therapeutic purposes.
20 rch has focused on utilizing these cells for therapeutic purposes.
21 nstrated the suitability of using (47)Sc for therapeutic purposes.
22 t step towards harnessing quiescent NSCs for therapeutic purposes.
23 ll transplantation (HSCT) for preventive and therapeutic purposes.
24 all-molecule agents for biotechnological and therapeutic purposes.
25 convenient pharmacological source of HNO for therapeutic purposes.
26 s and opportunities to manipulate miRNAs for therapeutic purposes.
27 thogenesis of CLL but could also be used for therapeutic purposes.
28 g novel-molecular targets for prognostic and therapeutic purposes.
29 ng strong interests in manipulating them for therapeutic purposes.
30 ammation, that could be further targeted for therapeutic purposes.
31 focus of efforts to manipulate cell fate for therapeutic purposes.
32 nvestigating potential targeting of HIFs for therapeutic purposes.
33  intracisternal administration of IL-1RA for therapeutic purposes.
34 ve the idea of chemically modulating it with therapeutic purposes.
35 ies to regenerate cardiovascular tissues for therapeutic purposes.
36 edirect the specificity of T lymphocytes for therapeutic purposes.
37 eting the receptor of choice for research or therapeutic purposes.
38 for siRNA delivery that can be developed for therapeutic purposes.
39  stem cells from normal tissue for potential therapeutic purposes.
40 cin as well as Skp2 silencing strategies for therapeutic purposes.
41 he context of disease could be exploited for therapeutic purposes.
42 ptors and could potentially be exploited for therapeutic purposes.
43 euromodulation of specific brain regions for therapeutic purposes.
44 aggregatory low-molecular mass molecules for therapeutic purposes.
45 al networks ex vivo for disease modeling and therapeutic purposes.
46 t might be exploited for both prognostic and therapeutic purposes.
47 functional plasticity might be exploited for therapeutic purposes.
48 iple sclerosis, which could be exploited for therapeutic purposes.
49 native approach to activate p53 function for therapeutic purposes.
50 nce of targeting the marrow niche in MPN for therapeutic purposes.
51 oligonucleotides on demand, for research and therapeutic purposes.
52 , in order to alter muscle contractility for therapeutic purposes.
53  poorly defined for genetic manipulation and therapeutic purposes.
54  to disrupt the G alpha(i)-GIV interface for therapeutic purposes.
55  means to screen for inhibitors of RNAPs for therapeutic purposes.
56 der to exploit this endogenous mechanism for therapeutic purposes.
57 ategies aimed at modulating M3R activity for therapeutic purposes.
58  to optimize the release of either agent for therapeutic purposes.
59 rts to develop pathway antagonists for human therapeutic purposes.
60 e potential of manipulating this pathway for therapeutic purposes.
61 ting Tregs and Tconvs can be manipulated for therapeutic purposes.
62  natural biological circuits for research or therapeutic purposes.
63 ential target to promote insulin release for therapeutic purposes.
64 ently large numbers of suppressive Tregs for therapeutic purposes.
65 arcinogenesis, but may also be exploited for therapeutic purposes.
66 sful manipulation of biological pathways for therapeutic purposes.
67 need be fully explored and might be used for therapeutic purposes.
68 lution, as well as the use of stem cells for therapeutic purposes.
69  production of less immunogenic proteins for therapeutic purposes.
70 ate this phenomenon for biotechnological and therapeutic purposes.
71 ry few well-identified validated targets for therapeutic purposes.
72 sive prostate cancer for both prognostic and therapeutic purposes.
73 etitively, it is being developed for various therapeutic purposes.
74 unctions, and to exploit these molecules for therapeutic purposes.
75 y may facilitate expansion of HSC number for therapeutic purposes.
76 lt it will be to exploit cell plasticity for therapeutic purposes.
77 also hampers rational targeting of DGAT1 for therapeutic purposes.
78 difiers, which may be directly exploited for therapeutic purposes.
79 nd ultimately can be used for diagnostic and therapeutic purposes.
80 implications for diagnostic, prognostic, and therapeutic purposes.
81 le genetic networks for biotechnological and therapeutic purposes.
82 in gliomas and how they may be exploited for therapeutic purposes.
83  of telomerase used to immortalize cells for therapeutic purposes.
84 f current attempts to target or use TAMs for therapeutic purposes.
85 oited to enhance cannabinergic signaling for therapeutic purposes.
86 ic progenitors from embryonic stem cells for therapeutic purposes.
87 he pharmacologic targeting of HIF-1alpha for therapeutic purposes.
88 erefore, these mouse Mabs cannot be used for therapeutic purposes.
89 CAM-1 interaction for biological studies and therapeutic purposes.
90  late-passage hESC lines may be unusable for therapeutic purposes.
91 notherapies potentiate NK cell responses for therapeutic purposes.
92 manipulation of hematopoietic precursors for therapeutic purposes.
93 es have hampered the use of CD133+ cells for therapeutic purposes.
94 dation for exploitation of this approach for therapeutic purposes.
95 cult, but it is important for prognostic and therapeutic purposes.
96  markers that may be used for diagnostic and therapeutic purposes.
97  hypothesize that they will prove useful for therapeutic purposes.
98 f compounds as a stratagem to deliver CO for therapeutic purposes.
99 ity of differentiating among these genes for therapeutic purposes.
100 hinders the use of lasers for diagnostic and therapeutic purposes.
101 the mammary epithelium for both research and therapeutic purposes.
102 -epigenetic interplay could be leveraged for therapeutic purposes.
103 ell biology, virology, and gene delivery for therapeutic purposes.
104  be relevant to manipulation of NK cells for therapeutic purposes.
105 ype that can be useful for diagnostic and/or therapeutic purposes.
106 ystem to be manipulated more effectively for therapeutic purposes.
107 anding the mechanisms of Tie2 activation for therapeutic purposes.
108 t functional properties for prophylactic and therapeutic purposes.
109 l specific controlled delivery of miRNAs for therapeutic purposes.
110 ne expression in vivo for imaging as well as therapeutic purposes.
111 in diverse cell types that may be useful for therapeutic purposes.
112  to interfere with microglial activation for therapeutic purposes.
113 in the development of chimeric receptors for therapeutic purposes.
114 ors that can be used for both diagnostic and therapeutic purposes.
115 loading of antigens onto dendritic cells for therapeutic purposes.
116 th of these can deliver anticancer cDNAs for therapeutic purposes.
117 nce our ability to manipulate stem cells for therapeutic purposes.
118  of NF-kappa B-dependent gene expression for therapeutic purposes.
119 te or inhibit the TLR4 signaling pathway for therapeutic purposes.
120  that this phenomenon might be exploited for therapeutic purposes.
121 fic peptide/MHC complexes for diagnostic and therapeutic purposes.
122 itis underwent vitrectomy for diagnostic and therapeutic purposes.
123 ventual deployment of lentivirus vectors for therapeutic purposes.
124 ady source of CCR6+ monocyte-derived DCs for therapeutic purposes.
125 AMs in the development of surrogate TCRs for therapeutic purposes.
126 eve high affinity ligands for diagnostic and therapeutic purposes.
127 e mechanisms is amenable to manipulation for therapeutic purposes.
128 manipulating the B7 costimulatory signal for therapeutic purposes.
129  of factor Xa with reversible inhibitors for therapeutic purposes.
130  tools in tumor targeting for diagnostic and therapeutic purposes.
131 d locally within selected target tissues for therapeutic purposes.
132  vitro and in vivo for both experimental and therapeutic purposes.
133 he induction of the formation of alveoli for therapeutic purposes.
134 logic, infection control and prevention, and therapeutic purposes.
135 to fluorescence detection for diagnostic and therapeutic purposes.
136 otein function and can also be modulated for therapeutic purposes.
137 that does not have psychoactive effects, for therapeutic purposes.
138 putative neoepitopes which are important for therapeutic purposes.
139 eostasis and disease and can be targeted for therapeutic purposes.
140 ffective EV-based markers for diagnostic and therapeutic purposes.
141 ugivorous mammal that could be leveraged for therapeutic purposes.
142 for targeting their downstream effectors for therapeutic purposes.
143 c stem cells (LSC) that can be exploited for therapeutic purposes.
144 ies for upregulating autophagic pathways for therapeutic purposes.
145 these effusions are vital for diagnostic and therapeutic purposes.
146 terations to enhance anticancer immunity for therapeutic purposes.
147 ammation-inducing and oncolytic capacity for therapeutic purposes.
148 ing strategy to produce functional cells for therapeutic purposes.
149 ween CD47 blockade or SIRPalpha blockade for therapeutic purposes.
150 ed before considering targeting of PTBP1 for therapeutic purposes.
151 ular mechanics for research, diagnostic, and therapeutic purposes.
152 can be developed for prophylactic as well as therapeutic purposes.
153 esses of the virus that may be exploited for therapeutic purposes.
154 cer vulnerabilities that may be targeted for therapeutic purposes.
155  of suppressed microRNAs in brain cancer for therapeutic purposes.
156 ein universe, and how we can target them for therapeutic purposes.
157 e and is highly important for diagnostic and therapeutic purposes.
158 gs could be useful in the design of MGBs for therapeutic purposes.
159 hat have been identified to be exploited for therapeutic purposes.
160 difficult to deliver for both diagnostic and therapeutic purposes.
161 drug, wildly prescribed for prophylactic and therapeutic purposes.
162  block diseased or injured blood vessels for therapeutic purposes.
163 obe their function or to manipulate them for therapeutic purposes.
164 ding of ABMR and be useful for diagnostic or therapeutic purposes.
165 etitive RNAs are required for diagnostic and therapeutic purposes.
166  regulating specific caspase-6 functions for therapeutic purposes.
167 for manipulating live cells for research and therapeutic purposes.
168  subcellular structure could be targeted for therapeutic purposes.
169 ly target skin-associated adipose tissue for therapeutic purposes.
170 ic receptors that reprogram immune cells for therapeutic purposes.
171 d how these mechanisms might be targeted for therapeutic purposes.
172 y could prove useful for suppressing HGP for therapeutic purposes.
173  for basic research in life sciences and for therapeutic purposes.
174 CRISPR-Cas9 in vitro and in vivo for various therapeutic purposes.
175 n produced and evaluated (pre)clinically for therapeutic purposes.
176 yed as veterinary drugs for prophylactic and therapeutic purposes.
177 nd the generation of a whole "bio-tooth" for therapeutic purposes.
178 h to modifying oligonucleotides intended for therapeutic purposes.
179 nt of small-molecule inhibitors of Vps34 for therapeutic purposes.
180 o study these ligases for basic research and therapeutic purposes.
181 loiting membrane compositional variation for therapeutic purposes.
182  a highly suitable target for diagnostic and therapeutic purposes.
183 nts in either soluble or cell-based TCRs for therapeutic purposes.
184  molecular tools to harness this pathway for therapeutic purposes.
185  cells and facilitate their exploitation for therapeutic purposes.
186 on the use of MSC are currently underway for therapeutic purposes.
187 s that might be exploited for diagnostic and therapeutic purposes.
188  5'-terminus is important for analytical and therapeutic purposes.
189  potentially streamlining iCM production for therapeutic purposes.
190  Tconv might be regulated differentially for therapeutic purposes.
191 ystem have key implications for research and therapeutic purposes.
192 n to be clinically useful for prognostic and therapeutic purposes.
193 ion of probes for target exploration and for therapeutic purposes.
194  the reprogramming of metabolic pathways for therapeutic purposes.
195  antagonize CSC in human prostate cancer for therapeutic purposes.
196 nd cautions against targeting the enzyme for therapeutic purposes.
197 n Union, while prednisolone is permitted for therapeutic purposes.
198 o knock down transcripts for experimental or therapeutic purposes.
199 erefore become an attractive target area for therapeutic purposes.
200 ology research towards promising utility for therapeutic purposes.
201 pain opens routes to exploit this system for therapeutic purposes.
202 lockade of vasopressin receptor subtypes for therapeutic purposes.
203 erefore appearing particularly promising for therapeutic purposes.
204 probiotic trials, were more likely to have a therapeutic purpose (114 [83.8%] vs 117 [44.2%]; differe
205  produce autologous differentiated cells for therapeutic purposes, a concept termed therapeutic cloni
206 tations associated with protein delivery for therapeutic purposes, a greater number of different deli
207 iliopancreatic ducts for both diagnostic and therapeutic purposes, adding significant clinical value
208 ers for diagnostic, prognostic, and targeted therapeutic purposes, although individual data sets may
209 ings may facilitate the use of hES cells for therapeutic purposes and as in vitro models of developme
210                                          For therapeutic purposes and based on this finding, we have
211 biopreservation protocols for cells used for therapeutic purposes and for cellular biofluids.
212 e, such intermediates could be exploited for therapeutic purposes and may reflect a conserved state a
213 ting NKp30-mediated NK cell cytotoxicity for therapeutic purposes and provides proof of concept that
214                    To harness iNKT cells for therapeutic purposes and to understand their role in viv
215 ranial electrodes in the auditory cortex for therapeutic purposes, and measured high-frequency (50-15
216 ides an opportunity to modulate immunity for therapeutic purposes, and to monitor the immune response
217 er its use in iPSC for research and possible therapeutic purposes; and we will review its use in musc
218 ation and administration of 1311 anti-B1 for therapeutic purposes are reviewed.
219 g probiotics to our diet for prophylactic or therapeutic purposes, as well as better regulation of th
220 ve antagonist hybrids can be very useful for therapeutic purposes because they enable us to stably ac
221 readily generating affinity-enhanced TCR for therapeutic purposes but demonstrate that minimal change
222 amber implants were originally developed for therapeutic purposes but have been used recently for the
223 iversification will not only be relevant for therapeutic purposes but might also shed light on the di
224 e that this mechanism could be exploited for therapeutic purposes by targeting PTPN22 with PKC inhibi
225 toplasty differs markedly when performed for therapeutic purposes compared with visual rehabilitation
226 pt of introducing genes into human cells for therapeutic purposes developed nearly 50 years ago as di
227 g an exciting source of genetic material for therapeutic purposes due to its exceptional biocompatibi
228 obes for both diagnostic (e.g., imaging) and therapeutic purposes (e.g., drug delivery).
229 iscovery using a fragment-based approach for therapeutic purposes for SOD1 associated motor neuron di
230 importance is also extensively exploited for therapeutic purposes, for instance in the treatment of n
231  mutKIT at diagnosis for both prognostic and therapeutic purposes, given that activated KIT potential
232 major impediment to the use of iPS cells for therapeutic purposes has been the viral-based delivery o
233 t common approach in harnessing bacteria for therapeutic purposes has been to deliver ex vivo enginee
234 o date, efforts to modulate miRNA levels for therapeutic purposes have been challenging to implement.
235                                          For therapeutic purposes, however, the bivalency of IgG and
236 eing utilized for diagnostic, prognostic, or therapeutic purposes, identifying driver genes that harb
237 can be developed for prophylactic as well as therapeutic purposes.IMPORTANCE The emergence of severe
238 fic ICAM-3-grabbing nonintegrin (L-SIGN) for therapeutic purposes in autoimmunity and infectious dise
239 ntibodies may prove useful for diagnostic or therapeutic purposes in cancer, infectious diseases, and
240 roved enzyme variants, including AMCase, for therapeutic purposes in chitin degradation.
241 prognosis, and prevention of cancer, and for therapeutic purposes in defined situations.
242 sing neurostimulation techniques over S1 for therapeutic purposes in dystonic patients.
243 velopment of blocking anti-CD1d antibody for therapeutic purposes in humans.
244 great potential as targets for diagnosis and therapeutic purposes in infectious diseases, allergies,
245 cating that pharmacological manipulation for therapeutic purposes in intestinal inflammatory conditio
246 tion mechanisms have also been harnessed for therapeutic purposes in many biotechnology applications.
247  potential risk of complement inhibition for therapeutic purposes in pregnancy.
248 tor numbers in harnessing CD4(+) T cells for therapeutic purposes in such conditions.
249 ssification may be useful for diagnostic and therapeutic purposes in the clinical practice.
250 SMA) may be targeted for both diagnostic and therapeutic purposes in the management of prostate cance
251  more than 60 y-as (131)I for diagnostic and therapeutic purposes in thyroid diseases.
252 esirability of increasing beta-cell mass for therapeutic purposes in type 2 diabetes.
253 for FcgammaR-related research as well as for therapeutic purposes in which only complement-mediated f
254 thod has occurred for special diagnostic and therapeutic purposes, including balloon valvuloplasties
255   The lymphatics are a target for a range of therapeutic purposes, including cancer therapy and vacci
256 the development of PSA inhibitors for cancer therapeutic purposes, including drugs that suppress PSA
257 nd for recombinant proteins for analytic and therapeutic purposes is increasing; however, most curren
258 possibility of exploiting these vesicles for therapeutic purposes is now being investigated.
259 ches to block or enhance polysialylation for therapeutic purposes is offered.
260 eta-particle-emitting radionuclides used for therapeutic purposes is sufficient to permit external de
261 with utilizing oligodeoxyribonucleotides for therapeutic purposes is their poor delivery into cells c
262 e of tumor-associated antigen (TAA) mRNA for therapeutic purposes is under active investigation.
263 is often added to a number of cell types for therapeutic purposes, it is important from a biomedical
264      Before these cells can be harnessed for therapeutic purposes, it is necessary to understand how
265  Controlling cell functions for research and therapeutic purposes may open new strategies for the tre
266         Targeting specific BMPR subunits for therapeutic purposes may thus provide an approach for ma
267 xample, the expression of a protein used for therapeutic purposes might be triggered by the recogniti
268 se metastatic relapse, stratify patients for therapeutic purposes, monitor response to drugs and ther
269 tibody (mAb) specific to IL13Ralpha2 for the therapeutic purpose of targeting IL13Ralpha2-expressing
270 geting strategy, either may be exploited for therapeutic purposes or may contribute to an unintention
271 rication of phantoms used for diagnostic and therapeutic purposes over a wide range of optical spectr
272  promising molecules have been developed for therapeutic purposes, particularly in the modulators of
273 acellular drug/biomacromolecule delivery for therapeutic purposes remains a great challenge.
274 tolerance-inducing potential can be used for therapeutic purposes remains poorly defined.
275 emisynthetic nanovesicles for diagnostic and therapeutic purposes requires novel approaches to load e
276                                          For therapeutic purposes, selective inhibition of individual
277                      Music has been used for therapeutic purposes since the beginning of cultural his
278   In general, these bacteria can be used for therapeutic purposes such as adjuvant therapy, drug-deli
279 udy enhances the interest of these cells for therapeutic purposes such as AML treatment.
280 ose of the study is to envisage personalized therapeutic purposes, such as autologous Fecal Microbiot
281 trical stimulation of the nervous system for therapeutic purposes, such as deep brain stimulation in
282 onstrated that cell populations intended for therapeutic purposes that are cultured in heterologous a
283                                 Besides, for therapeutic purposes, the effect of these nanoparticles
284  aimed at inhibiting prenylating enzymes for therapeutic purposes, the function of prenylation remain
285 Given the potential use of these mutants for therapeutic purposes, the immunomodulatory properties of
286 tion in eukaryotic cells and may be used for therapeutic purposes to knock down genes implicated in d
287  that may be exploited for prognostic and/or therapeutic purposes to reduce prostate cancer progressi
288 ulator of autophagy that may be targeted for therapeutic purposes to treat LSDs and other autophagic
289 ignalling through the downstream pathway for therapeutic purposes under clinically relevant condition
290 ly and reversibly targeting cardiac mRNA for therapeutic purposes using locked nucleic acid-modified
291 ss organ donation once intensive care with a therapeutic purpose was deemed futile and brain death (B
292 -1-targeted disruption of cell signaling for therapeutic purposes was first advanced in 1989 with the
293                                          For therapeutic purposes, we first genetically modified MSCs
294                                          For therapeutic purposes, we validated the use of an anti-uP
295 enerated with weekly stimulation of LCLs for therapeutic purposes were also studied.
296 ivo modification of the cellular genome with therapeutic purposes, which can be based on gene supplem
297                            Targeting HDL for therapeutic purposes will require understanding its biol
298 opportunities to modulate erythropoiesis for therapeutic purposes will undoubtedly emerge.
299 t this mechanistic link can be exploited for therapeutic purposes with orally active chemical chapero
300 ry circuits, which are commonly targeted for therapeutic purposes with potentiator drugs.

 
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