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1                                     However, there remain a large number of TFs ( approximately 800)
2                                     However, there remain a limited number of mouse models of cleft l
3 ing predators, and advertising toxicity [1], there remain a multitude of species that display conspic
4                                     However, there remain a number of diseases for which there are no
5                                     However, there remain a number of technical challenges to be solv
6 ienced rapid growth over the last few years, there remain a relatively small number of material class
7 ssfully in murine embryonic stem (ES) cells, there remain a set of nearly two thousand genes that hav
8                                     However, there remain a subset of patients who have continued sev
9 ions used automatic tube current modulation, there remained a large variation of practice, on the ord
10 tatin therapy candidates at 55 years of age, there remained a significant association between cumulat
11 gitation from baseline to post intervention, there remained a statistically significant difference (p
12                                     However, there remained a wide variation in practice, sometimes b
13                               I propose that there remains a central role for the item (or its equiva
14                                     However, there remains a challenge to design a practical path fro
15 ulates avoid energy infrastructure; however, there remains a common perception that ungulates habitua
16 cultural production throughout the world, so there remains a compelling need to develop new vector an
17                                     However, there remains a considerable gap between genotype-to-gen
18 loss of VHL is an almost ubiquitous finding, there remains a conspicuous lack of targetable genetic d
19 ng to re-open and relax stay-at-home orders, there remains a continued need for careful surgical sche
20                                        Thus, there remains a critical need for HH inhibitors with dif
21                                              There remains a critical need for randomized clinical tr
22  quantification have decreased considerably, there remains a critical need for researchers to optimiz
23                                     However, there remains a critical need to define the precise temp
24 ecies and environmental conditions; as such, there remains a critical need to focus research efforts
25                                     As such, there remains a critical need to identify key regulators
26                                     However, there remains a dearth of evidence guiding treatment in
27 rovements in the microbial diagnostic field, there remains a disconnect between clinicians and some p
28  have been developed to improve performance, there remains a gap between promising laboratory results
29  potential of new drugs and small molecules, there remains a gap in the ability to efficiently delive
30                                     However, there remains a general gap in understanding among clini
31                                Consequently, there remains a great need for reliable serum markers fo
32 edict the anti-cancer therapeutic responses, there remains a great need to develop highly accurate pr
33 s event could have been anticipated and that there remains a high chance of exceeding observed record
34 anticipated, and that in the current climate there remains a high chance of exceeding the observed re
35  although even with antimicrobial treatment, there remains a high risk of pregnancy loss.
36 gnosis and high relapse after treatment, but there remains a lack of biomarkers and effective targete
37                                              There remains a lack of clarity regarding the influence
38 tabolism are known to be implicated in MNDs, there remains a lack of clarity regarding the key functi
39                                     However, there remains a lack of consensus on the optimal route a
40 y can be enhanced by proteomic evidence, but there remains a lack of consensus on the performance of
41                                     However, there remains a lack of detailed, systematic studies ass
42                                     However, there remains a lack of direct structural evidence to su
43                                Nevertheless, there remains a lack of effective, targetted diagnostic
44                                              There remains a lack of evidence concerning both pharmac
45 psoriasis patients using an IL-17 inhibitor, there remains a lack of evidence to suggest a causal rel
46                                     However, there remains a lack of good evidence for the efficacy o
47 ew vessels from the preexisting vasculature, there remains a lack of insight of the nuclear transcrip
48                                     However, there remains a lack of practical methods to detect and
49                                     However, there remains a lack of statistically sound frameworks t
50 e of death in pediatric neuroblastoma, where there remains a lack of therapies to target this stage o
51                                     However, there remains a lack of understanding regarding ripple d
52                                              There remains a large discrepancy between the known gene
53  variety of computational genomics problems, there remains a large gap in our understanding of how th
54 factors are well established as carcinogens, there remains a large knowledge gap of others owing to t
55                                              There remains a limited role for angioplasty because thi
56                                              There remains a major unmet need for successful manageme
57                                              There remains a need for a broadly applicable, hernia-sp
58                            Despite advances, there remains a need for a method that combines the simp
59                                              There remains a need for additional high-quality longitu
60 e recent improvements in sequencing methods, there remains a need for assays that provide high sequen
61 ing cause of death in developed nations, and there remains a need for cardiac therapeutic systems tha
62                                              There remains a need for consensus on practical aspects
63 ols are inconvenient to use in practice, and there remains a need for easy-to-use cross-platform tool
64 ment of advanced non-small-cell lung cancer, there remains a need for effective treatments for progre
65                                     However, there remains a need for further improvements in sensiti
66                                              There remains a need for heightened levels of concern re
67 ed the effects of key individual parameters, there remains a need for multi-factor experiments (e.g.,
68 n space, has significant clinical value, but there remains a need for neuroimaging techniques to impr
69                                     However, there remains a need for standardization of preanalytica
70                                              There remains a need for such compounds with the balance
71 ed structure in data to generate hypotheses, there remains a need for testing hypotheses and interpre
72                                     However, there remains a need for the development of analytical m
73 toward the development of new IR probes, but there remains a need for those that can extend the exper
74 he emergence of site-specific endonucleases, there remains a need for tools capable of specifically d
75 ocesses that are enriched in the genes sets, there remains a need for tools that identify enrichment
76                                              There remains a need in clinics and research to have sim
77  costs and eliminate complicated procedures, there remains a need to address probe costs and generali
78                                              There remains a need to analyze data across institutions
79                                     However, there remains a need to anticipate supply given the rapi
80                                         Yet, there remains a need to assess the AHQ's clinical applic
81 aneous mastocytosis (CM) have been proposed, there remains a need to better define subforms of cutane
82  key contributors to metastatic disease, and there remains a need to better understand and target the
83               Notwithstanding the foregoing, there remains a need to develop a conceptual framework t
84                                              There remains a need to develop noninvasive predictors o
85 er still carries a poor prognosis, and thus, there remains a need to elucidate the molecular mechanis
86  and mortality associated with this disease, there remains a need to elucidate the molecular mechanis
87                                Nevertheless, there remains a need to focus on the "last mile" in remo
88                                              There remains a need to identify new sensitive diagnosti
89                                              There remains a need to identify novel pro-resolution dr
90 rapeutic potential in severe infections, but there remains a need to substantiate clinical benefit.
91 n tissue development and cell proliferation, there remains a paucity of approaches to investigate the
92                Despite routine clinical use, there remains a paucity of data on their effectiveness a
93 have substantially advanced in recent years, there remains a paucity of evidence for treatment.
94                                      However there remains a paucity of information about overall cap
95 noid system has immunomodulatory properties, there remains a paucity of information on the effects of
96                                              There remains a paucity of information on the status of
97                                              There remains a paucity of real-world observational evid
98                      Despite these advances, there remains a paucity of robust and accepted biomarker
99 e being a significant healthcare cost burden there remains a paucity of studies in the literature eva
100  smell can accomplish astonishing feats, yet there remains a prevailing belief that olfactory languag
101 ated control of clade B HIV-1 infection, yet there remains a relative paucity of data regarding the r
102                                     However, there remains a scarcity of evidence about the performan
103                                Despite this, there remains a scarcity of software packages that provi
104 crease in women entering surgical residency, there remains a sex disparity in surgical leadership.
105                                     However, there remains a shortage of specific databases that can
106 gand interactions to identify new compounds, there remains a shortage of specific databases with prec
107 ial meningitis in children has decreased but there remains a significant burden of disease in adults,
108                                     However, there remains a significant disconnect between theory an
109  of patients on the transplant waiting list, there remains a significant gap between the need for tra
110 aureus is a leading cause of bacteremia, yet there remains a significant knowledge gap in the identif
111                                     However, there remains a significant lack of generators capable o
112                                              There remains a significant need for development of effe
113 As a result, outcomes are generally poor and there remains a significant unmet need for novel therape
114 f high-quality evidence and robust guidance, there remains a significant variation in some elements o
115 several potent agonists have been described, there remains a strong need for suitable tracers to inte
116                                     However, there remains a substantial challenge to produce long-st
117                      Despite these advances, there remains a substantial need for more high-quality e
118                                              There remains a substantial number of MoAs that were har
119                                              There remains a substantial unmet medical need in hemoph
120                                         Yet, there remains a surprising lack of tools for GSE testing
121 able progress in DNA sequencing technologies there remains a trade-off between short-read platforms,
122                                              There remain also needs to understand broader categories
123 us studies in this area in recent years, but there remains an imperative to demonstrate that the curr
124                                     As such, there remains an important clinical need to develop ways
125                                              There remains an important need for prophylactic anti-Eb
126 d differences in case mix between operators, there remains an inverse relationship between PCI operat
127                                 Furthermore, there remains an unmet demand for an efficient survey of
128                                              There remains an unmet dermatological need for innovativ
129                                   Therefore, there remains an unmet need for a novel therapeutic appr
130 ious diseases caused by pathogenic bacteria, there remains an unmet need for diagnostic tools that ca
131                                        Thus, there remains an unmet need for early diagnostic and pro
132 global threat from drug-resistant superbugs, there remains an unmet need for simple and accessible di
133 notechnological solutions to biosensing, yet there remains an unmet need in the development of biosen
134                                     However, there remains an unmet need to turn molecular self-assem
135                                       Hence, there remains an urgent need for antidiabetic therapeuti
136 ts in column technology and instrumentation, there remains an urgent need for creating innovative app
137 ite significant advancements over the years, there remains an urgent need for low cost diagnostic app
138                                              There remains an urgent need for rapid diagnostic method
139                                     However, there remains an urgent need to develop new vaccines for
140  of AILDs and liver transplantation evolves, there remain areas of unmet needs.
141  therapy for insulin-dependent diabetes, but there remain challenges towards achieving this goal(1-6)
142 talyzed C(sp(3))-C cross-coupling reactions, there remain challenging bond formations.
143                                     However, there remains concern about their efficacy and safety.
144                                              There remains concern regarding the occurrence of noncom
145 type 1 retinopathy of prematurity (ROP), but there remain concerns about systemic toxicity.
146  transcatheter aortic valve replacement, yet there remain conflicting reports about the effect of sex
147                                              There remain conflicts and uncertainties in specific cas
148 sed by critical care organizations; however, there remains confusion about what shared decision makin
149 n and the development of cold hardiness, but there remain considerable gaps deserving further researc
150 ite this significant pharmaceutical success, there remain considerable limitations to broad medicinal
151                                              There remains considerable debate over the active form o
152 echanisms of signal production and response, there remains considerable debate over the functional ro
153 ommon task in biological investigations, yet there remains considerable room for improvement in align
154                        Given these findings, there remains considerable room for improvement, especia
155 forests respond with increased productivity, there remains considerable uncertainty as to how the lon
156                                              There remains considerable uncertainty in how anthropoge
157 rent histopathological classification system there remains considerable uncertainty in predicting tum
158  a leading cause of worldwide disability but there remains considerable uncertainty regarding its neu
159                                              There remains considerable variability in the distributi
160 d the debate over how many tree species grow there remains contentious.
161                       Despite their success, there remain critical barriers to the more widespread us
162                        This notwithstanding, there remain critical development issues and knowledge g
163 dergoing percutaneous coronary intervention, there remains debate about differences in efficacy and t
164 entary imaging is occasionally required when there remains diagnostic uncertainty following transesop
165 lowing discussion among the consensus group, there remained disagreement in 10 cases (kappa = 0.91; 9
166 axSpA disease concept is universally agreed, there remains disagreement about operationalizing aspect
167 Hypertonic saline is used predominantly, yet there remains disagreement about whether hypertonic sali
168                                          But there remain enormous uncertainties about the atomistic
169 AV pandemics can be traced to avian origins, there remains ever-present concern over emerging IAVs wi
170 e for the preparation of aromatic compounds, there remain few methods that allow their conversion int
171                                     However, there remain few operationally simple methods for their
172 nance of contemporary patterns of diversity, there remain few standardized biogeographic comparisons
173 idelines are appropriate for cardiology, but there remain fundamental differences between trauma and
174                                 For example, there remain fundamental open questions on the phase dia
175                                              There remain gaps in knowledge concerning how vascular m
176                                     However, there remain gaps in our knowledge, primarily regarding
177                                     Although there remain gaps in our understanding of how the interc
178  iterative process of model development, and there remains great opportunity for advancing our unders
179                                     However, there remains great variability in the current clinical
180                                              There remain however several points of contention.
181                                              There remain, however, many challenges related to the ac
182                                              There remains, however, a need for methods to propel and
183                                              There remains, however, a need to examine eDNA persisten
184                                              There remains, however, a pressing need to elucidate str
185                                              There remains, however, an unexplained link between hypo
186                                              There remains, however, the need for an efficient APRM c
187 f the breadth of this public health problem, there remain important gaps in scientific knowledge rega
188      Mortality rates continue to be high and there remain important opportunities for further improve
189 ly on inefficient phenotypic approaches, and there remains incomplete understanding of AMR mechanisms
190                                              There remains insufficient evidence to provide guidance
191                                              There remain issues such as how to cluster molecular seq
192 le nucleotide polymorphisms (SNPs); however, there remains large room for improvements in running tim
193 ave increased diversity in food choices, but there remains limited evidence linking these innovations
194                                              There remains limited insight into the pathophysiology a
195    However, despite its clinical importance, there remains limited understanding of mechanisms underl
196                                              There remains limited understanding of the complex and d
197  of charged energetic particles, for decades there remained little direct observational evidence that
198 d States have increased in recent years, yet there remains little attention on liposuction, or debulk
199 lume fluid administration for major surgery, there remains little consensus on optimal strategies, du
200 However, despite attention in model systems, there remains little data on how recombination rate vari
201 T1) can contribute to neuronal excitability, there remains little information on the physiological ro
202                                              There remains little national data evaluating the associ
203                                              There remain major challenges to implementing pulse oxim
204  the Expanded Program on Immunization (EPI), there remain major challenges to more effective vaccinat
205 and powerful analysis methods are available, there remain many challenges to reliable tree building.
206 e databases, and better data analysis tools, there remain many challenges to the routine use and impl
207                                              There remain many more genetics variants with small effe
208     However, despite their apparent success, there remain many open questions about their intrinsic p
209 t has been evaluated in clinical trials, and there remain many opportunities to further investigate k
210 merous cellular targets have been described, there remain many questions about the mechanism of NSP1
211 ge and advances in prevention and treatment, there remain many questions about this decline.
212                                Despite this, there remain many regions for which no atmospheric monit
213 ector secretion and host defence mechanisms, there remain many unanswered questions about fundamental
214 ion referred to as "reverse seroconversion." There remain many uncertain areas that warrant further s
215                                              There remain many uncertainties regarding this pathway.
216                                              There remain metabolic deficits following restoration of
217 blast cells is a well-recognized phenomenon, there remains minimal data on differences in MDR activit
218 chanisms on simplified membrane systems, but there remain missing connections between the complex env
219 nergy nuclear reactions, and we contend that there remains much interesting science to be done in thi
220                                              There remains much scientific, clinical, and ethical con
221 f current management of ischemic stroke, but there remains much to be learned about mechanisms of neu
222 g the surfaces of these frameworks, although there remains much to be learned about the origins of th
223 ifferences between broad tissue types exist, there remains much to be understood about the splicing f
224 ature, but with nearly seventy-five species, there remains much to explore in this genus.
225 ry of 2-phosphaethynolate is burgeoning, but there remains much to learn about this ligand, for examp
226                                   Currently, there remains much unknown about CRF-dependent regulatio
227                                              There remain no uniform classification criteria that are
228                                      Overall there remain no validated biomarkers in the youth popula
229 n characterizing and modeling this response, there remains no consensus as to the mechanism that driv
230 munologic injury to the renal allograft, yet there remains no consensus on how best to monitor drug t
231 herapies have improved patient survival, but there remains no definitive cure.
232                                              There remains no direct evidence on effects of prenatal
233 eserved ejection fraction (HFpEF) in humans, there remains no evidence-based therapies for HFpEF.
234 establishes a persistent infection for which there remains no feasible cure.
235  leading cause of infant hospitalization and there remains no pediatric vaccine.
236 pite intense research for the past 25 years, there remains no safe and effective vaccine available.
237 ecular resistance mechanisms is limited, and there remains no standardized DST method.
238 hat target proteins for therapeutic benefit, there remains no substitute for the natural properties o
239 ver, despite importance for clinical trials, there remains no transcriptomic biomarker for FSHD progr
240  with high rejection rates in MPS1 children, there remains no treatment to prevent blindness or resto
241  vaccines in preventing infectious diseases, there remain numerous globally devastating diseases with
242 ed organic matter ((3)CDOM*) reactivity, but there remain open questions about the reaction kinetics
243                                              There remain open questions in the signaling networks, t
244 espite its widespread use over four decades, there remain open questions regarding its fundamental li
245                                              There remain opportunities for improvement in medication
246       While early results remain encouraging there remain opportunities for improvement.
247 these early years following introduction, so there remains potential for further disease reductions.
248  not yet achieved any commercial success, as there remain problems with capacity fade after extended
249 ictions and total allowable catch (TAC), but there remain problems with compliance and high levels of
250                                 Nonetheless, there remain psychiatric domains unique to humans.
251 f recurrent cardiovascular events after ACS, there remain questions about how aggressively to reduce
252                                Despite this, there remain remarkably few studies investigating the us
253                                 Nonetheless, there remains reticence among transplant surgeons to tra
254 spectra obtained from cross-linked peptides, there remains room for improvement.
255  is frequently associated with cataract, but there remains scant information about DS cataract morpho
256 andidates is fully assessed by these trials, there remains scope for the discovery of inhibitors from
257 tant viruses of grapevine but, despite this, there remain several gaps in our understanding of its bi
258                                              There remain several great and lingering challenges to b
259 h in HCV therapeutic development approaches, there remain several key obstacles to the broad implemen
260                                     However, there remain several open challenges in designing adapti
261                                              There remain several outstanding questions in spatial ec
262                                     However, there remain significant challenges in the synthesis of
263 been made on materials performance; however, there remain significant concerns about operational and
264 h hiring additional staff may be beneficial, there remain significant financial limitations for many
265                       Despite these efforts, there remain significant gaps in our knowledge concernin
266                     SUMMARY BACKGROUND DATA: There remain significant gaps in our understanding of ac
267 rt of efforts to eliminate malaria, however, there remain significant gaps in our understanding of mo
268                                     However, there remain significant knowledge gaps about the variat
269                                              There remain significant regional disparities in the man
270 ing advances in the field of nanotechnology, there remain significant research gaps and the opportuni
271 tment for biologically plausible covariates, there remained significant associations of total 25-hydr
272                                Nevertheless, there remained significant disagreements, centered large
273 AN practice parameters was readily apparent, there remained significant variability across all 5 cate
274 ers provide maps of the "spatial gradients," there remains significant confusion because of the lack
275 nder local or general anaesthesia exist, and there remains significant debate within the field regard
276  in the pathology of CNS disorders, however, there remains significant uncertainty about the neuropro
277           Despite this substantial progress, there remains significant work to be accomplished.
278 sets of identified palmitoyl-proteins and so there remains some uncertainty over what constitutes the
279                   Owing to conflicting data, there remains some uncertainty regarding the most benefi
280 g the obligate liver stage of infection, yet there remains sparse knowledge of specific host regulato
281 GPCRs) can treat multiple diseases; however, there remains substantial interest in the development of
282 roved treatment such as methadone, for which there remains the best evidence of efficacy, may be the
283                                     However, there remains the need for alternative insecticidal acti
284                                              There remains the need, however, for a soluble, versatil
285                                              There remain thousands of potentially important genomic
286                                     However, there remain unanswered questions about the mechanism of
287                                              There remain unanswered questions surrounding surgical c
288 etic variants associated with schizophrenia, there remains uncertainty about the causal genes involve
289 scribed sex differences in asthma incidence, there remains uncertainty about the role of female sex h
290                                              There remains uncertainty about the true specificity of
291                                     However, there remains uncertainty about whether these thin sheat
292 recedented opportunities for drug discovery, there remains uncertainty concerning the path to the cli
293                                    Moreover, there remains uncertainty of which thresholds are the mo
294 erstanding of the molecular characteristics, there remains uncertainty regarding epidemiologic trends
295        For displaced femoral neck fractures, there remains uncertainty regarding the effect of a tota
296                                 Furthermore, there remains uncertainty regarding the relative importa
297 limb loss, morbidity and mortality; however, there remains unmet therapeutic needs for arterial revas
298 ged 9 years and older has been licensed, but there remains urgent medical need for a vaccine that is
299 ong the countries where these are available, there remains variability.
300 ss to adequate care than that at present, as there remains variation in survival between European reg

 
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