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1 from Thermus thermophilus (Tth), an extreme thermophile.
2 provides a wealth of data on proteins from a thermophile.
3 t and below the optimal temperature for this thermophile.
4 es from the thermophilic fungus Sporotrichum thermophile.
5 esence of more than 30 putative PBPs in this thermophile.
6 ncrease in highly connected residues in this thermophile.
7 superfamily, which typically are missing in thermophiles.
8 halophiles, or ('sulphur-dependent') extreme thermophiles.
9 microbial communities that include anaerobic thermophiles.
10 stent pattern of signature differences among thermophiles.
11 lyses, as well as protein engineering within thermophiles.
12 e homologous protein structures from extreme thermophiles.
13 and psychrophiles, but not within the GAPDH thermophiles.
14 tudy of the mechanism of protein splicing in thermophiles.
15 found to be analogous to those occurring in thermophiles.
16 dence on this trace metal in early anaerobic thermophiles.
17 ence, tapirins are specific to these extreme thermophiles.
18 microscope that enables live-cell imaging of thermophiles.
19 branch, the protein is found exclusively in thermophiles.
20 upon folding is higher in mesophiles than in thermophiles.
21 derstanding the evolution of mesophiles from thermophiles.
22 ure or compactness of the denatured state in thermophiles.
23 is greatly diverged from that of homologs in thermophiles.
24 haracterizations than those from prokaryotic thermophiles.
25 urrently cultivated are sulphur-metabolizing thermophiles.
26 ncode a novel DNA repair system conserved in thermophiles.
27 ing psychrophiles, from mesophiles, and from thermophiles.
28 ies have been shown to be present in several thermophiles [6][7][8], no sequences have been found tha
30 pulate Chaetomium thermophilum, a eukaryotic thermophile, along with various biochemical applications
33 izes the native L-shaped fold in the extreme thermophile and which has been incorporated into much la
36 es have primarily focused on nonmethanogenic thermophiles and halophiles, leaving it unclear whether
40 A study including isolates has shown that thermophiles and other bacteria with high optimum growth
41 bic effects allow for discrimination between thermophiles and psychrophiles, but not within the GAPDH
43 te in the eco-evolutionary feedbacks between thermophiles and their habitats and suggest moderately a
45 ith homologs of Aquifex aeolicus (an extreme thermophile) and Chlamydia trachomatis (an obligate intr
48 eria that hosted these particular genes were thermophiles, and neither hyperthermophiles nor mesophil
49 in properties of proteins in mesophiles and thermophiles, and the likely structural and functional c
51 nit protein L27, was cloned from the extreme thermophile Aquifex aeolicus, and the protein was overex
52 erse species, including one from the extreme thermophile Aquifex aeolicus, which suggests that RusA m
56 yses and experimental data suggest that both thermophiles are capable of hydrolyzing all major polysa
59 ults support the hypothesis that proteins of thermophiles are subject to unusually strong purifying s
61 esult in more stable proteins (i.e. those of thermophiles) are also tuned to have a higher tolerance
62 Our technique allows exploiting eukaryotic thermophiles as source for purifying thermostable native
63 tal gene transfer, resulted in trees showing thermophiles as the earliest evolved bacterial lineage.
64 activator from Aquifex aeolicus, an extreme thermophile), as well as its ATPase domain alone, and re
65 Holdemania spp. and increased Streptococcus thermophiles), as were various enzyme levels and KEGG pa
67 haracterization of recombinant PyrR from the thermophile Bacillus caldolyticus and the crystal struct
68 5N-edited TROSY NMR spectra of TRAP from the thermophile Bacillus stearothermophilus over an extended
69 , L10(L12) 4 was expressed from the moderate thermophile Bacillus stearothermophilus to quantitativel
70 ermal stability of adenylate kinase from the thermophile Bacillus stearothermophilus were monitored d
72 forming the S4-5' domain rRNA complex from a thermophile, Bacillus stearothermophilus, and points out
75 lity is prevalent in prokaryotes, especially thermophiles, but uncommon in eukaryotic organisms, ther
76 s a substrate for growth of the cellulolytic thermophile Caldicellulosiruptor bescii lacking a functi
77 ized without any pretreatment by the extreme thermophile Caldicellulosiruptor bescii that has been me
78 e dismutase (SOD) to test if this eukaryotic thermophile can provide insights into macromolecular mec
80 Bacillus species plus bacterial and archaeal thermophiles contain related proteins of similar functio
82 enabling the same approach to be amenable to thermophile-derived cellulases or to the separation of m
85 ucleotide CpG=CG is underrepresented in many thermophiles (e.g., M. jannaschii, Sulfolobus sp., and M
88 sed on the solution structure of an isolated thermophile HAMP domain in which G235 defines a critical
91 ies most correlated with the proteins of the thermophile include higher residue volume, higher residu
92 cal to those of cultivated chemolithotrophic thermophiles, including the hydrogen-oxidizing Calderoba
93 d to those of other saccharolytic, anaerobic thermophiles is most similar to that of Caldicellulosiru
94 cterium animalis subsp Lactis, Streptococcus thermophiles, Lactobacillus bulgaricus, and Lactococcus
95 the mesophile Methanococcus voltae (Mv), the thermophile M. thermolithotrophicus (Mt) and the hyperth
96 in substrates and that metabolism in extreme thermophiles may use sugars in both ring and straight ch
97 ate modeling of helix-rich proteins found in thermophiles, mesophiles, and organisms that flourish ne
98 tal structures of adenylate kinases from the thermophile Methanococcus thermolithotrophicus and the m
99 us vannielii, Methanococcus maripaludis, the thermophile Methanococcus thermolithotrophicus, and hype
100 e nine-residue loop at the ortholog from the thermophile Methanothermobacter thermautotrophicus (MtOM
101 show that Ptr2 and a Lrp homologue from the thermophile Methanothermococcus thermolithotrophicus (Mt
102 e Methanobacterium formicicum; hMfB from the thermophile Methanothermus fervidus; and hPyA1 from the
103 te the method, we analyse the genomes of the thermophile Moorella thermoacetica and the mesophile Ace
104 e use of enzymes from extremophiles, such as thermophiles or alkaliphiles, offers the potential to in
105 her cellobiose dehydrogenase from Corynascus thermophiles or bilirubin oxidase from Myrothecium verru
107 at O-2'-ribose methylation in this bacterial thermophile plays a reduced role in thermostabilization
108 in threonyl-transfer RNA synthetase from the thermophile Pyrococcus abyssi that forms complementary v
110 of cellobiose dehydrogenase from Corynascus thermophiles (recDHCtCDH) expressed recombinantly in Esc
111 ic effect is particularly strong for extreme thermophiles, since the spontaneous deamination reaction
112 omplexes show structural similarity with the thermophile-specific enzyme reverse gyrase, which cataly
113 teria), as well as a mixture of two moderate thermophiles Sulfobacillus thermosulfidooxidans for oper
114 ndole-3-glycerol phosphate synthase from the thermophile Sulfolobus solfataricus (sIGPS) and the alph
115 re very different from those of the archaeal thermophile Sulfolobus solfataricus growing in the same
116 pa, and hpol iota and Dpo4 from the archaeal thermophile Sulfolobus solfataricus We found that hpol e
117 renarchaeal DNA polymerases from the extreme thermophiles Sulfolobus acidocaldarius and Pyrodictium o
118 maripaludis S2), an acidophilic and aerobic thermophile (Sulfolobus solfataricus P2), and an anaerob
121 entous bacteriophage PH75, which infects the thermophile T. thermophilus, assembles in vivo at 70 deg
122 script cleavage factor GreA from the extreme thermophiles, T. thermophilus and Thermus aquaticus.
123 XXA motif is enhanced to a greater extent in thermophiles than in mesophiles, suggesting that helical
124 he gain in enthalpy upon folding is lower in thermophiles than in mesophiles, whereas the loss in ent
125 stability is significantly more favorable in thermophiles than in mesophiles, whereas the maximal sta
126 ous substitutions was significantly lower in thermophiles than in nonthermophiles, and this effect wa
127 rulating, sulfate-reducing, chemoautotrophic thermophile that can fix its own nitrogen and carbon by
128 ents of the highly active mannanase from the thermophile Thermoanaerobacterium polysaccharolyticum.
130 nism of the citrate synthase from a moderate thermophile, Thermoplasma acidophilum (TpCS), are compar
131 In lineages leading to extant enzymes in thermophiles, thermostability increased from ancestral t
132 Crystal structures of ODP from Td and the thermophile Thermotoga maritima (Tm) in the Fe[III](2)-O
133 oplasmic region of a sensor HK, one from the thermophile Thermotoga maritima in complex with ADPbetaN
134 from the mesophile Escherichia coli and the thermophile Thermotoga maritima, subunit dissociation ac
136 phate dehydrogenase (GAPDH) from the extreme thermophile Thermus aquaticus has been solved at 2.5 Ang
138 acterial ribonucleases H (RNases H) from the thermophile Thermus thermophilus and the mesophile Esche
141 We have constructed a mutant of the extreme thermophile Thermus thermophilus in which the prmA gene
142 n comparison to E. coli, the proteome of the thermophile Thermus thermophilus is significantly more s
143 We have shown that S15 from the extreme thermophile Thermus thermophilus represses the translati
144 he filamentous virus PH75, which infects the thermophile Thermus thermophilus, consists of a closed D
149 DNA-dependent RNA polymerase (RNAP) from the thermophile, Thermus thermophilus HB8, was purified to e
153 that MUG-K68N, UNG-N123 and family 5 Thermus thermophiles UDGb-A111N can form bidentate hydrogen bond
154 base excision repair pathway, suggests that thermophiles use a mechanism similar to that used by mes
155 rchaeon Methanococcus jannaschii, an extreme thermophile, was subcloned and expressed in Escherichia
156 this biochemical pathway is found in extreme thermophiles, we examined the published genome sequence
157 the universal tree of life, suggesting that thermophiles were among the first forms of life on earth
158 the recombinant enzymes that originated from thermophiles were expressed in Escherichia coli and puri
159 roved in the cores of proteins isolated from thermophiles when compared to proteins from mesophiles.
160 role of modifications contained in RNA from thermophiles, which is to reduce regional RNA flexibilit
161 aeon Methanobacterium thermoautotrophicum, a thermophile with an optimal growth temperature of 65 deg
162 Asgard ancestor of eukaryotes was a moderate thermophile, with an optimal growth temperature around 5
164 logs for structural biology; yet, eukaryotic thermophiles would provide more similar macromolecules p