ライフサイエンスコーパス: thiol

1 nalogy with the known reactivity of HNO with thiol.

2 reduction from 27.1% down to 13.0% oxidized thiol.

3 n EPR spectrum characteristic of the trapped thiol.

4 ) sensor array for the discrimination of six thiols.

5 nd reveal new, dynamic properties in SAMs of thiols.

6 te carbonyl sulfide (COS) in the presence of thiols.

7 nines' versatile photochemical behavior with thiols.

8 ane, were studied and compared with those of thiols.

9 and waste-free method to access alcohols and thiols.

10 "fingerprint" pattern identification for six thiols.

11 e core of shishijimicin A upon activation by thiols.

12 d either when BISMORX was mixed with protein thiols.

13 iols imaged by BISMORX were indeed lysosomal thiols.

14 arities among structures and reactivities of thiols.

15 espect to half-life, pH, and availability of thiols.

16 ed derivatives, NDM-1 by compounds bearing a thiol, a thiosemicarbazide or thiosemicarbazone moiety,

17 ed LCEs are prepared via a radical-mediated, thiol-acrylate chain transfer reaction.

18 n), here we use a much more robust reaction (thiol-acrylate/thiol-ene 'double-click' chemistry) to ob

19 ity, representing the first description of a thiol-activated bacterial superantigen.

20 e Cy, required for photostabilization, or Cy-thiol adduct formation, necessary for super-resolution m

21 ties, namely, allyl, amine, carboxylic acid, thiol, aldehyde, and catechol, were prepared and chemica

22 Here we describe the ability of a binary thiol-amine solvent mixture to dissolve the bulk bournon

23 copper (I) and copper (II) coordinating with thiol/amino group.

24 matter (NOM; Suwannee River DOM) and 15 LMM thiols, an internally consistent thermodynamic data set

25 e; H is a dissociable proton) with a pendant thiol and [Fe(NO)((TMS)PS2)((TMS)PS2CH(3))] (2) bearing

26 rheology to first characterize the effect of thiol and allyl sulfide crosslink structures on degradat

27 nctions formed between gold electrodes using thiol and amine contact groups.

28 nal groups in peptides including S-protected thiol and azide.

29 mplexes comprising a tridentate N(2) S donor thiol and its analogous N(4) S(2) donor disulfide ligand

30 The decrease in free amino, thiol and tryptophan groups and increase in molecular we

31 examples in S-H insertion reactions of aryl thiols and alpha-carbonyl sulfoxonium ylides.

32 rodes functionalized with different aromatic thiols and amines suggests that the primary role of the

33 ed with other conventional ligands including thiols and amines, metal-carbene bonds that are stable u

34 which enables the oxidative coupling between thiols and amines, two readily available and inexpensive

35 The reaction of thiols and anhydrides to form ring opened thioester/acid

36 A broad range of thiols and azetidinols bearing electron-donating aromati

37 Redox cycling of single thiols and disulfides has been unresolvable due to a num

38 covalent binding mechanisms towards cysteine thiols and other amino acids.

39 Protein solubility, accessible thiols and secondary structures were measured in dough,

40 iphatic alcohols, phenols, carboxylic acids, thiols and sulfonamides were found to be competent nucle

41 substituents on aromatic nitriles and amino thiols and testing their reactivity and ability to form

42 viticulture), which can impact on amounts of thiols and their precursors.

43 Several thiols and thiol precursors have been reported previousl

44 through induction of synergistic oxidative, thiol, and metal stress.

45 Various amines, alcohols, thiols, and amino acid derivatives are effective nucleop

46 essing and recycling abilities of a range of thiol-anhydride elastomers, glasses, composites and phot

47 Systemic free thiols are amenable to nutritional or therapeutic interv

48 Thiols are found to be involved in the lysosomal degrada

49 Thiols are important natural molecules with diverse func

50 Volatile thiols are very strong-smelling molecules that can impac

51 the amount of quinone compounds able to trap thiol aromas.

52 d by measuring color, polyphenol content and thiol aromas.

53 fit to further ascertain the presence of the thiol at the polymer chain-end.

54 ly sensitive and differentiable detection of thiols at various concentrations in human blood serums,

55 (VAN) was studied on the 1H-1,2,4-triazole-3-thiol-Au (T3T-Au) electrode.

56 N-terminal amidine rendering the side chain thiol available for further modification.

57 scuss the current views on the activities of thiol-based peroxidases in peroxide-mediated redox signa

58 organisms, this modification could initiate thiol-based redox relays and modify target enzymes, rece

59 uantitatively blocking surface thiols with a thiol binding ligand (qBBr), we show that surface thiols

60 of ~3.33 angstrom, suggesting increasing Sb-thiol binding.

61 tivity caused an enhanced flux of (35)S into thiol biosynthesis, especially in roots.

62 These data point to a novel "thiol-blocked" [(PDT)Mo(V)O(S(Cys))(thiolate)](-) struct

63 Oxidation of cysteine thiols by physiological reactive oxygen species (ROS) in

64 lcohol (PhFOH)/BF(3).OEt(2)/K(3)PO(4), while thiols can be protected in good to excellent yield using

65 entrations of reactants without the need for thiol catalysts.

66 Here, we examined the role of cell surface thiols, cellular ligands with the highest affinity for H

67 evated abundance of the low molecular weight thiols coenzyme A (CoA) and glutathione in S47 cells.

68 ce-exposed hydrophobicity and decreased free thiols, compared to the starting defatted flour.

69 g(II) following the production of the Hg(II)-thiol complex.

70 ially bind with transferrin via inner-sphere thiol complexation.

71 Thiol compounds including cysteine, glutathione and phyt

72 s was reflected by a significant decrease in thiol concentrations in the same sample.

73 As a test-bed reaction, we monitored 48 thiol conjugate additions to a Meldrum's acid derivative

74 We describe the development of a new "thiol conjugation assay" for identification of novel sma

75 This allowed the alkylated thiol-containing and UV-reduced cysteine-containing pept

76 ing known compounds, whereas other important thiol-containing metabolites could also exist.

77 itu derivatization of free thiol groups from thiol-containing metabolites such as glutathione and cys

78 Derivatization of thiol-containing metabolites with CHC-Mal for MALDI MSI

79 ctrometry analyses revealed the oxidation of thiol-containing polymer chain-ends during sample prepar

80 Thiol-containing polymer chains can thereby be indirectl

81 or the chain-end identification of different thiol-containing polymer chains.

82 Pd-protein OACs can cross-couple with other thiol-containing proteins to arrive at homogeneous prote

83 d RNA, only cells expressing UPRT synthesize thiol-containing RNA.

84 GSH is a low-molecular-weight thiol-containing tripeptide (l-gamma-glutamyl-l-cysteiny

85 complexes for resolution of multimers, and a thiol-containing version promoted crystallization.

86 The Zn(II)-IMAC system selectively bound the thiol-containing Zn(II)-ACE1 inhibitors captopril and om

87 The thiol content (3-sulfanylhexyl acetate (3SHA) and 3-sulf

88 its quality control depended solely on free thiol content.

89 UV-vis experiments suggest the formation of thiol-coordinated iodine(I) intermediates.

90 are more efficient traps for HNO than their thiol counterparts.

91 cysteine residue, preventing the subsequent thiol coupling with a reactive AlexaFluor 680 acceptor d

92 ested intermediates, and investigate them by thiol cross-linking.

93 re of peptides 2a-c and 3a-c to the reactive thiol cysteamine revealed that DeltaAla-containing pepti

94 High surface thiol density and elevated expression of the ROS scaveng

95 e demonstrate here that SpAhpD exhibits weak thiol-dependent peroxidase activity and, unlike the prev

96 pation of 2-Cys peroxiredoxin (2-Cys PRX), a thiol-dependent peroxidase, in the control of the reduci

97 rstanding of redox regulatory principles and thiol-dependent redox relays of Prxs in subcellular comp

98 re hydrogen peroxide sensors and the role of thiol-dependent signaling networks in the transmission o

99 pendent hydroxylase, Rieske dioxygenase, and thiol dioxygenase.

100 s overall structure is consistent with other thiol dioxygenases, closer inspection of the active site

101 ur knowledge of the substrate specificity of thiol dioxygenases.

102 trast to binding behaviors observed in other thiol dioxygenases.

103 Regulation of enzyme activity based on thiol-disulfide exchange is a regulatory mechanism in wh

104 The thiol-disulfide exchange reaction is of specific interes

105 we demonstrate detection of single-molecule thiol-disulfide exchange using a label-free optoplasmoni

106 physical (hydrophobic effect) and chemical (thiol-disulfide interchange) interactions.

107 e respiratory chain, glycolysis also enables thiol/disulfide exchange-mediated folding of bacterial c

108 gation of lactoferrin during heating through thiol/disulphide interchange.

109 levels may also be related to the effect of thiol drugs on oxidative stress.

110 e classified aslow molecular weight volatile thiols (e.g. H(2)S, methanethiol) which impact the smell

111 Cy regeneration via photoinduced thiol elimination is favored by adduct absorption spectr

112 a much more robust reaction (thiol-acrylate/thiol-ene 'double-click' chemistry) to obtain highly uni

113 re achieved by a combination of Michael-type thiol-ene addition and copper(I)-mediated alkyne-azide c

114 With well-ordered molecular networks, thiol-ene chemistry accesses polymer materials with a wi

115 The fastHDX thiol-ene microchip is fabricated entirely using thiol-e

116 Here, we investigate thiol-ene micropillar scaffold sheets ("synthetic paper"

117 l-ene microchip is fabricated entirely using thiol-ene photochemistry.

118 Since free-radical thiol-ene polymerization is not inhibited by oxygen, the

119 hogonal crosslinking mechanisms-photocurable thiol-ene reactions and condensation reactions-to exerci

120 tion, demonstrating structures 3D printed in thiol-ene resin by means of tomographic volumetric VAM.

121 udy presents the first report of VAM-printed thiol-ene resins.

122 Mechanical characterization of this thiol-ene system, with varied ratios of isocyanurate and

123 ng (e.g., free-radical chain polymerization, thiol-ene, photomediated redox) of natural and synthetic

124 oduce methyl groups at positions beta to the thiol ester in the growing polyketide chain.

125 increases the hydroxyl reactivity of A2ML1's thiol ester.

126 n a thermolysin serine residue and the A2ML1 thiol ester.

127 alpha-macroglobulin (alphaM) superfamily use thiol esters to form covalent conjugation products upon

128 Both of A2ML1s' thiol esters were reactive toward the amine substrate gl

129 However, it is difficult to discriminate one thiol from another because of the similarities among str

130 is rigid, always protecting the active-site thiols from the oxidizing environment of the periplasm.

131 ted candidate from E50C to P54C as the other thiol function site, for forming longitudinal disulfide

132 c constants for Hg(II) complexes formed with thiol functional groups in bacterial cell membranes of t

133 We succeeded in introducing thiol functional groups onto three lysine residues in Ig

134 the stabilization of gold nanoparticles with thiol-functionalised hybrid organic-inorganic polyoxomet

135 Here we address these issues using a thiol-functionalized 2D conjugated metal-organic framewo

136 -)), the derivative of the abundant cellular thiol glutathione (GSH).

137 (5 mW cm(-2) ) in the presence of a soluble thiol (glutathione at 15 x 10(-3) m), and a photoinitiat

138 amines suggests that the primary role of the thiol group in 2-ABT is to anchor the NH(2) group near t

139 ic nickel ions and covalent bonding with the thiol group of Cys322, respectively.

140 tylene group is directly introduced onto the thiol group of cysteine and can be used for copper-catal

141 diates in the reaction and protected protein thiol group oxidation.

142 to its substrate peptide by connecting a Cys-thiol group to the beta-carbon of an upstream Asn residu

143 des, the most commonly used reagents to link thiol groups (of Cys) to drugs and labels.

144 d protein solubility and induced exposure of thiol groups as well as a shift in secondary structure d

145 nding, the resulting metal surface with free thiol groups can be easily rebonded with a second hydrog

146 ted the formation of acrylamide adducts with thiol groups from both metabolites and protein residues,

147 We performed in situ derivatization of free thiol groups from thiol-containing metabolites such as g

148 which demonstrated that the introduction of thiol groups improved the adsorption capacity.

149 e and cryo-electron microscopy, we show that thiol groups of cysteine residues undergo S-glutathionyl

150 Amino-, hydroxy-, and thiol-groups in the meta positions of C-phenylnitrile im

151 s determined to contain a high percentage of thiol (>80%).

152 n of conjugated enynones with thiophenols or thiols has been developed.

153 binding ligand (qBBr), we show that surface thiols have no significant effect on Hg(II) methylation,

154 9) is positioned to recognize 5hmC through a thiol-hydroxyl hydrogen bond.

155 th LysoTracker Red DND-99 confirmed that the thiols imaged by BISMORX were indeed lysosomal thiols.

156 s coordinate the iron center with their free thiols in a monodentate binding mode, in sharp contrast

157 We focused on thiols in beverages and their release mechanisms from pr

158 Volatile thiols in beverages can be classified aslow molecular we

159 p a new analytical approach for screening of thiols in plants, using four vegetal examples and beginn

160 Inspired by the crucial roles of thiols in vivo, a proof-of-concept sensor array through

161 s a wide range of heteroaromatic halides and thiols, including alkyl and heteroaryl thiols, leading t

162 ated abundance of low molecular weight (LMW) thiols, including glutathione (GSH) and coenzyme A (CoA)

163 aperone holdase family, RidA and CnoX, whose thiol-independent activation mechanism differs from that

164 ward synthetic route to convert nucleophilic thiols into electrophilic, thiol-selective vinylphosphon

165 lly relevant electron-rich heteroarenes with thiols is reported.

166 iscovery of >3000 reactive and/or accessible thiols labeled in their native cellular environments in

167 s and thiols, including alkyl and heteroaryl thiols, leading to a variety of thioethers in good isola

168 ent metal-thiolate bonds by exposure to free thiols, leading to the remarkable observation of the tot

169 Trx1 and thiol levels were higher in IL-15- than in IL-2-primed N

170 The results indicated that thiol-lignocellulose molecules may have different influe

171 Thiol-lignocellulose sodium bentonite (TLSB) nanocomposi

172 mbining either with low molecular mass (LMM) thiols like Cys, Hg(Cys)(Mem-RS), or with neighboring O/

173 would have abnormal redox status due to bio-thiols, like glutathione (GSH), which constitute the mos

174 ts appreciable amounts of low molecular mass thiol (LMM-RSH) compounds reaching concentrations of abo

175 ry and structural biology that this cysteine-thiol lyase (C-T lyase) is a PLP-dependent enzyme that m

176 Thiol-maleimide chemistry was utilised to covalently lig

177 Expected or unexpected disulfide/thiol mapping was then carried out based on the search r

178 tch is rapid, reversible, and accompanied by thiol-mediated changes in the structures and activities

179 However, knowledge of thiol metabolism in plants is limited to studying known

180 , particularly with respect to the nature of thiol-metal bonding.

181 about the spontaneous formation of covalent thiol-metal bonds.

182 ith isotopically labeled acetyl-alanine; (3) thiol Michael addition of an isotopically labeled acetyl

183 The thiol-Michael addition (TMA) is a powerful methodology t

184 Thiol modified DNA specific aptamers were used to functi

185 article formulation of polymerized siRNA and thiol-modified glycol chitosan nanoparticle-was used for

186 e, we have measured the surface coverage for thiol-modified single-strand deoxyribonucleic acid (ssDN

187 OTAP binary lipid bilayer tethered on alkane thiol molecular cushions.

188 sphate for neutralizing the charges and a di-thiol molecule (2,2'-(ethylenedioxy) diethanethiol (EDT)

189 Herein, the discovery of a unique thiol molecule is reported, namely bismuthiol I, which c

190 reacted with the low-molecular-weight (LMW) thiol mycothiol, protecting it from overoxidation.

191 g was similar to that of the original triple-thiol nonconjugated rHSA variants (0.88 and 0.25 mum for

192 sequence unwinds an alpha-helix, placing the thiol of Cys69 into the mEndoG active site.

193 erein we report that converting the terminal thiol of the E. coli ACP 4'-phosphopantetheine arm into

194 en algae were exposed to MeHg complexes with thiols of larger size and more "branched" chemical struc

195 gnificantly more stable than the traditional thiols on Au system.

196 biquity, self-assembled monolayers (SAMs) of thiols on coinage metals are difficult to study and are

197 y activity in many diseases by reacting with thiols on the adaptor protein, Keap1.

198 t of antibody variants (trisulfides and free-thiols) on product qualities of different antibodies.

199 chains can be more sensitively detected than thiol ones (the low pK(a) of sulfonic acids facilitating

200 ides that were recalcitrant to reaction with thiol or amine nucleophiles under mild aqueous condition

201 approach to prepare sulfonyl fluorides using thiols or disulfides, as widely available starting mater

202 for bioconjugation more often with cysteine thiols or lysine amines.

203 be released to glutathione (a physiological thiol) or to other complexing agents.

204 te of CblC suppressed the NO(2)Cbl-dependent thiol oxidase activity, whereas the disease-associated R

205 zed to aquo-cob(III)alamin or enter a futile thiol oxidase cycle forming GSH disulfide.

206 ive stress was analyzed by measuring protein thiol oxidation and antioxidant mRNA.

207 tion, and endotoxemia accompanied by protein thiol oxidation and downregulation of antioxidant gene e

208 However, it is demonstrated herein that thiol oxidation can be advantageously taken into profit

209 To force thiol oxidation we used THF without any antioxidant stab

210 he impact of several nitroxyl donors and the thiol-oxidizing agent diamide on cardiac myocyte protein

211 m identifies heterogeneous protein disulfide/thiol patterns in a de-novo fashion with artifact contro

212 as applied to characterize unknown disulfide/thiol patterns of the recombinant cyclophilin 1 monomer

213 ono were identified to contain two disulfide/thiol patterns, of which C41-C169 linkage was confirmed

214 4 was observed for a surface prepared with a thiol PEGylated aptamer HS-(CH(2))(6)-OP(O)(2)O-(CH(2)CH

215 Thiols play vital roles in mediating physiological proce

216 Poly(1H-1,2,4-triazole-3-thiol) (poly(T3T)) conductive film was coated successful

217 The second part deals with thiol precursors and the different release mechanisms in

218 Several thiols and thiol precursors have been reported previously in differ

219 with UV light had little to no effect on the thiol precursors.

220 n of 2-deoxy S-glycosides in the presence of thiols, probably by in situ generation of catalytic HNO(

221 se of the nitrodibenzofuran (NDBF) group for thiol protection and found it to exhibit a faster rate t

222 he most common photoremovable group used for thiol protection is the o-nitrobenzyl group and related

223 sociated with the modification of regulatory thiol proteins.

224 itch or mediate electron transfer with other thiol proteins.

225 quently invoked mechanism of concerted amine/thiol proton transfer and C-S bond formation and instead

226 es, facilitated by an intramolecular pendant thiol proton.

227 the intersection of metal-catalyzed HAT and thiol radical trapping HAT catalytic cycles to be essent

228 When simple thiols reacted reversibly with CBT, the thioimidate mono

229 dergo base-promoted beta-elimination to form thiol-reactive alpha,beta-unsaturated aldehydes, which t

230 r pilin subunit for subsequent labeling with thiol-reactive maleimide dyes.

231 Integrating single-cell PTM analysis with thiol-reactive organoid barcoding in situ (TOBis) enable

232 that lactam analogues with muted nonspecific thiol reactivities constitute a better electrophile for

233 ctone showing a positive correlation between thiol reactivity and bioactivity.

234 show good correlation at the outer limits of thiol reactivity but less so for compounds with intermed

235 cell lysates suggested that general proteome thiol reactivity correlates with cytotoxicity.

236 Despite their expected general thiol reactivity, these compounds display considerable d

237 ctronically different groups affords diverse thiol reactivity.

238 A similar in vitro model that mimics the thiol redox conditions of human blood has been previousl

239 nsition from an oxidizing to a more reducing thiol redox environment in the mitochondrial matrix.

240 ne are cytosolic, the molecular basis of the thiol redox homeostasis in the single mitochondrion of t

241 e iodoacetyl tandem mass tag (iodoTMT)-based thiol redox proteomics.

242 n and a shift towards a more reduced protein thiol redox state in old hearts.

243 We identify a global operation of thiol redox switches that is required for optimal usage

244 nctional interplay among pathways regulating thiol-redox status, metabolic adaptation, and cellular r

245 ripheral APCs, gamma-IFN-inducible lysosomal thiol reductase (GILT) is critical for MHC class II-rest

246 tion of the glutaredoxin GRXS17, a member of thiol reductase families in the model plant Arabidopsis

247 ical conditions, providing insights on these thiol-related attributes and allowing for more informed

248 tablished to study and predict the impact of thiol-related attributes on safety or efficacy of intrao

249 ls are effective tools to monitor changes of thiol-related attributes under physiological conditions,

250 n competitive PCET activations of amides and thiols relevant to catalytic olefin hydroamidation react

251 n of HNO with reactive sulfur species beyond thiols remains relatively unexplored.

252 liminating matrix effects due to residual of thiol resin in the sample solutions.

253 Solutions obtained after thiol resin treatment were measured to demonstrate the a

254 The thiol rHSA variants exhibited up to 95% monomeric stabil

255 Because they are thiol-rich reducing molecules with high Cu(I) affinity,

256 roducts of hydrogen sulfide (H(2)S)-mediated thiol (RSH) modification, are additional potential targe

257 ofiled directly in cultured cells, achieving thiol saturation in a few minutes at submillimolar conce

258 vert nucleophilic thiols into electrophilic, thiol-selective vinylphosphonothiolates: In this protoco

259 3)-, OH-, COOH-, and NH(2)-terminated alkane-thiol self-assembled monolayers (SAMs).

260 Activated Thiol Sepharose-based proteomic approach to quantify rev

261 al modification of proteins by addition of a thiol (-SH) group onto reactive cysteine residues: a pro

262 n of a NO moiety to a protein cysteine (Cys) thiol (-SH) to form an S-nitrosothiol (SNO).

263 translational modification (PTM) of cysteine thiols (SNO), modulates the activity of proteins that re

264 Using thiol-specific crosslinking we provide rigorous proof of

265 recursor ion scan mode, after extraction and thiol-specific derivatisation with 4,4'-dithiodipyridine

266 essential cysteines that can interfere with thiol-specific labelling.

267 Here, we show that the thiol-specific peroxidase peroxiredoxin-4 (Prdx4) direct

268 tress required both cysteines, implying that thiol status in this protein directly influences folding

269 ey function as a collective cohort to manage thiol stress.

270 Biological thiols such as glutathione are of particular interest du

271 To identify individual operational protein thiol switches, we captured the fast release of metaboli

272 ransformation processes in bacterium-NOM-LMM thiol systems.

273 esses, indicating a direct link between both thiol systems.

274 We show that mechanochemically generated thiol-terminated polymers undergo a Michael-type additio

275 is reflected by a reduction in systemic free thiols, the major components of the antioxidant machiner

276 MTST could trap thiols through its methanethiosulfonate group to form th

277 s the possibility to monitor the presence of thiols through oxidation and chemiluminescence of the re

278 modification, the oxidation of two cysteine thiols to a disulfide bond, during the catalytic cycle o

279 philic substitution reaction in alcohols and thiols to afford 3-alkoxy- and 3-arylthio-substituted 1,

280 st-translationally oxidizes beta2AR cysteine thiols to Cys-S-sulfenic acids (Cys-S-OH).

281 The oxidation of alkyl thiols to disulfides has been achieved under mild condit

282 transient covalent modifications of cysteine thiols to modulate the activities of regulatory kinases

283 ient sulfa-Michael addition reaction of aryl thiols to trisubstituted alpha-fluoro-alpha,beta-unsatur

284 We term this technique EPR thiol-trapping.

285 nzaldehyde reacts with a range of amines and thiols under Lewis acid catalysis.

286 en juices, significant elevation of varietal thiols (up to 10-fold) occurred in the wines derived fro

287 e (CHC-Mal), for selective detection of free thiols using MALDI MSI.

288 ory half-life of a high hFcRn-binding triple-thiol variant conjugated with AF680 (t (1/2) = 22.4 h) c

289 ghly complicated disulfide linkages and free thiols via liquid chromatography-tandem mass spectrometr

290 dines that selectively react with biological thiols via nucleophilic aromatic substitution (S(N)Ar).

291 ntified a PEG hydrogel formulation that uses thiol-vinyl sulfone Michael addition for crosslinking.

292 r oxa[5]-, [6]-, [7]-, and -[19]helicene (di)thiols was prepared.

293 Compound identity for prospective thiols was then proposed using HPLC with high resolution

294 ause of the incompatibility of the generated thiol with typical hydrogenation catalysts.

295 By quantitatively blocking surface thiols with a thiol binding ligand (qBBr), we show that

296 drogenated to the corresponding alcohols and thiols with excellent tolerance for amide, ester, and ca

297 ch impact the smell negatively, and volatile thiols with higher boiling points that contribute positi

298 ld lead to prospecting studies that identify thiols with potential roles in metabolic pathways, nutri

299 t part of this review is devoted to volatile thiols, without considering small malodorous molecules.

300 e materials using the efficient nucleophilic thiol-yne reaction between a dipropiolamide and dithiol