ライフサイエンスコーパス: thrice

1 season in a split-plot design and replicated thrice.

2 gen levels in the sub-plots, each replicated thrice.

3 t, BQ123 (1mg/kg, intravenously administered thrice: 30 min, 2h and 4h after MCAO for a total dose of

4 Ripasudil was administered to mice thrice a day after allogeneic corneal transplantation.

5 amethasone (steroid) or 0.1% control protein thrice a day for 10 days.

6 Crenolanib (100 mg thrice a day) was given from day 9 until 72 hours before

7 -1 cells were treated with lupeol (40 mg/kg) thrice a week and surrogate biomarkers were evaluated in

8 jection of curcumin or PEITC (6 and 5 mumol; thrice a week for 28 days), beginning a day before tumor

9 DIM-C-pPhCF3 (60 mg/kg thrice a week for 4 weeks) inhibited the growth of impla

10 tudy of COVID-19 positive subjects (n = 40), thrice-a-day delivery of the calcium-rich hypertonic sal

11 Among adults vaccinated at least thrice and infected more than 6 months earlier, spike le

12 nned contrast volume restricted to less than thrice and preferably twice the CCC might be valuable in

13 zyme digest of the red cowpea type was about thrice as effective as that of the cream cowpea type in

14 iferative responses generated by vaccination thrice at monthly intervals with HPV16 L2E7E6 were compa

15 ees C and 4 degrees C temperatures preserved thrice both the encapsulated and non-encapsulated phloro

16 between 2030 and 2050, equivalent to nearly thrice California's peak demand, and could incur up to $

17 was significantly less nephrotoxic than was thrice daily (mean% change in creatine -4.5% [once daily

18 ed to receive either valacyclovir (VACV) 2 g thrice daily (n = 40) or placebo tablets (n = 47) for 90

19 -12 twice daily (P=0.005) and 34% with BG-12 thrice daily (P=0.01).

20 However, a dosing frequency of thrice daily (t.i.d) was required in these studies to el

21 reotide subcutaneously: initial dose 100 mug thrice daily and up to 200 mug thrice daily.

22 SAR 1118 ophthalmic drops administered thrice daily deliver therapeutic levels of SAR 1118 in t

23 wice daily during week 1, followed by 6 mmol thrice daily during week 2.

24 ty of oral vorinostat 100 to 300 mg twice or thrice daily for 14 days followed by 1-week rest.

25 activity of SAR 1118 eye drops administered thrice daily for 2 months at 1% (0.3 mg/eye/d) and 5% (1

26 were topically treated with 0.1% HGF or PBS thrice daily for 5 days.

27 00 mg lanthanum carbonate or matched placebo thrice daily for 96 weeks.

28 XA through IV (n = 168) vs placebo (n = 169) thrice daily for maximum 30 days.

29 d support a rationale for a 1000 mg twice or thrice daily intravenous dose in humans or saline as a c

30 zed in a 1:1 ratio to receive 0.1% nepafenac thrice daily or 0.09% bromfenac eye drops twice daily fo

31 aphy were randomly assigned sildenafil 40 mg thrice daily or matching placebo for 9 weeks.

32 phylaxis included ganciclovir 1000 mg orally thrice daily prescribed for 90 d in D-/R+ cases and 180

33 e superiority of 3 weeks of sildenafil 50 mg thrice daily versus placebo (mixed-effect linear models)

34 7% with BG-12 twice daily and 26% with BG-12 thrice daily vs. 46% with placebo, P<0.001 for both comp

35 -label study in which oral gabapentin 300 mg thrice daily was given for every other chemotherapy trea

36 ed to receive either hydralazine HCL (25 mg, thrice daily) or a placebo for 12 months.

37 ive either idalopirdine 90 mg per day (30 mg thrice daily) or placebo.

38 00 mg twice daily), and itraconazole (200 mg thrice daily) until beta-d-glucan (BDG) levels were nega

39 to NAM (750 mg twice daily) plus LC (1000 mg thrice daily), NAM plus LC placebo, LC plus NAM placebo,

40 either ursodeoxycholic acid alone (10 mg/kg thrice daily, n = 19) or partial biliary diversion (n =

41 h the dose increased to a maximum of 12.5 mg thrice daily, together with octreotide subcutaneously: i

42 idodrine orally at an initial dose of 7.5 mg thrice daily, with the dose increased to a maximum of 12

43 r disease were treated with budesonide, 3 mg thrice daily.

44 e to take over prescribing and dose twice or thrice daily.

45 dose 100 mug thrice daily and up to 200 mug thrice daily.

46 dose (MTD) was 200 mg twice daily or 250 mg thrice daily.

47 -, or high-dose sildenafil or placebo orally thrice daily; within-group dose depended on weight.

48 ange in creatine -4.5% [once daily] vs 3.7% [thrice daily]; adjusted mean difference -8.0%, 95% CI -1

49 Patients in the thrice-daily arm reported a higher abdominal discomfort

50 icantly lower with twice-daily BG-12 (0.22), thrice-daily BG-12 (0.20), and glatiramer acetate (0.29)

51 % in the twice-daily BG-12 group, 18% in the thrice-daily BG-12 group, and 27% in the placebo group,

52 the twice-daily BG-12 group and 0.19 in the thrice-daily BG-12 group, as compared with 0.36 in the p

53 , and new T(1)-weighted hypointense lesions (thrice-daily BG-12) (nominal P<0.05 for each comparison)

54 cant except for the annualized relapse rate (thrice-daily BG-12), new or enlarging T(2)-weighted hype

55 reductions: twice-daily BG-12, 44%, P<0.001; thrice-daily BG-12, 51%, P<0.001; glatiramer acetate, 29

56 As compared with placebo, twice-daily BG-12, thrice-daily BG-12, and glatiramer acetate significantly

57 sability progression with twice-daily BG-12, thrice-daily BG-12, and glatiramer acetate versus placeb

58 pharmacokinetic profile of a standard 500 mg thrice-daily dosing regimen over 5 days and biofilms wer

59 iate to continue buprenorphine-naloxone with thrice-daily dosing.

60 taken orally twice-daily if weight <80 kg or thrice-daily if weight >80 kg).

61 g [n = 238], or 15 mg [n = 236]) or prandial thrice-daily insulin lispro (n = 708).

62 f unilateral lower-limb immobilization, with thrice-daily leucine (LEU; n = 8) or placebo (PLA; n = 8

63 e-daily milked glands, and between once- and thrice-daily milked glands, suggests that mammary apopto

64 beit with smaller alveoli, was maintained in thrice-daily milked glands.

65 Differential once- and thrice-daily milking of lactating goats was also associa

66 ble patients assigned to the twice-daily and thrice-daily regimens showed substantially reduced inter

67 wo days before challenge, volunteers began a thrice-daily, 7-day course of investigational product ad

68 Indirect calorimetry was measured thrice during acute, late, and chronic phases among 305,

69 d a mental health inventory in 2017-2019 and thrice during the pandemic.

70 ions in the non-dominant leg (90 degrees /s) thrice each week.

71 overweight/obese children reported more than thrice frequent rescue treatments (3.7 vs 1.1 treatments

72 le-cuff upper arm oscillometric measurements thrice in 129 master athletes aged 35-86 years and estim

73 Persistently (40%), Highly (24% MS-PD twice/thrice), Minimally (15% MS-PD once), and Never (21%) Dis

74 steopontin-null and WT mice treated with TPA thrice or with DMBA followed by TPA for 11 weeks showed

75 pared with an equivalent total dose given on thrice- or single-injection-per-week schedule.

76 chlamydia received azithromycin, distributed thrice over the following year.

77 ss as the dose increased from 1 to 10 mg/kg (thrice per day).

78 e of cruciferous vegetable-derived L isomer, thrice per week beginning at 6 weeks of age, significant

79 rcinogen, N-nitrosomethylbenzylamine (NMBA), thrice per week for 5 weeks.

80 ug (8 mg/kg i.p.) at the time of surgery and thrice per week for the duration of the study (48 days).

81 sion when testing is increased from twice to thrice per year suggests that obtaining 2 reliable tests

82 s when testing is performed once, twice, and thrice per year, respectively.

83 ontains four cadherin-like ectodomains and a thrice tandemly repeated region enriched in threonine, s

84 eived that incorporate not once or twice but thrice the features of a pH-switchable [2]rotaxane with

85 e and the following coda ranges from once to thrice the group delay of the primary impulse (the group

86 ce of squamous cell carcinoma in males to be thrice the incidence in females.

87 0.001) and at the aggregate level had nearly thrice the number of hospital beds (403,522 [75%] vs 137

88 yed sufficiently (for a duration of at least thrice the time until the peak of the unmitigated outbre

89 Pneumatic descemetopexy was attempted thrice (twice with SF6, once with air) over a week's spa

90 Fourteen patients were thrice vaccinated 2 weeks apart with autologous DCs puls

91 1.1.529) was observed for thrice vaccinated individuals with omicron breakthrough

92 Using biomarker twice or thrice was cost effective only if biomarker cost was <$7

93 nt diallyl trisulfide (DATS; 1 and 2 mg/day, thrice/week for 13 weeks beginning at age 8 weeks) signi

94 als supports the use of subcutaneous epoetin thrice weekly (150 U/kg tiw) for a minimum of 4 weeks.

95 als supports the use of subcutaneous epoetin thrice weekly (150 U/kg) for a minimum of 4 weeks.

96 of 25 mg twice weekly (cohort one) and 25 mg thrice weekly (cohort two) until disease progression.

97 kly throughout, daily (intensive phase) then thrice weekly (continuation phase), and daily (intensive

98 ries of 119 dialyses in 51 patients dialyzed thrice weekly (r = 0.9952; mean absolute error, 1.97 +/-

99 doses up to 6.0 mg/kg when administered as a thrice weekly 2-hour infusion for 3 consecutive weeks.

100 Patients undergoing hemodialysis thrice weekly appear to have no major benefit from a hig

101 lpha-2b SC was begun on week 4 and continued thrice weekly at 5 MU/m2 for 2 years.

102 Both medications were provided along with thrice weekly behavioral counseling and incentives conti

103 Thrice weekly dosing throughout therapy, and twice weekl

104 aroxaban 10 mg daily plus vitamin K2 2000 ug thrice weekly during 18 months.

105 (n=91) by infusion in the hemodialysis lines thrice weekly during hemodialysis sessions.

106 = 47), panobinostat was administered orally thrice weekly every week in combination with bortezomib

107 or 200 microg of rIFN- gamma 1b or placebo, thrice weekly for 10 weeks, plus standard therapy with i

108 receive 3, 5, or 10 MU of interferon alfa-2b thrice weekly for 12 weeks.

109 nib (10 mg/kg body weight) or vehicle (DMSO) thrice weekly for 18 weeks, a dose schedule that inhibit

110 for 8 wk, followed by isoniazid and rifampin thrice weekly for 18 wk.

111 horts, the maximally assessed regimen (10 mg thrice weekly for 2 weeks) was used.

112 re exposed to 180 mjoules/cm2 UVB radiation, thrice weekly for 24 weeks.

113 d in the dorsal skin of two C3H mice treated thrice weekly for 28-33 weeks with UV radiation and etha

114 Standard hemodialysis was thrice weekly for 3.5-4 hours, minimum Dialysis Std Kt/V

115 Rituximab administered thrice weekly for 4 weeks demonstrates clinical efficacy

116 ts of subcutaneous IFN-gamma 1b (200 microg) thrice weekly for 6 months versus placebo in 32 patients

117 eceive oral vitamin D3 [50,000 IUs (1.25 mg) thrice weekly for 8 wk and 50,000 IU every other week fo

118 azid, rifampin, pyrazinamide, and ethambutol thrice weekly for 8 wk, followed by isoniazid and rifamp

119 g on 20% sub-maximal force control, occurred thrice weekly for five weeks.

120 ization to iron sucrose 100 mg IV or placebo thrice weekly for up to 2 weeks.

121 In Tax transgenic mice, PS-341 administered thrice weekly inhibited tumor-associated NF-kappaB activ

122 x open-label ketamine infusions administered thrice weekly over 2 weeks.

123 bo, or 3 million units of interferon alfa-2b thrice weekly plus daily ribavirin for 48 weeks.

124 or HSV DNA polymerase chain reaction [PCR]), thrice weekly rectal mucosal secretions (for HIV-1 RNA a

125 elapse was significantly higher in arms with thrice weekly therapy throughout (6.8; 95% confidence in

126 nd ADR (10.0; 95% CI, 2.1-46.7) in arms with thrice weekly throughout and higher rates of failure (3.

127 R) for 4 dosing schedules: daily throughout, thrice weekly throughout, daily (intensive phase) then t

128 measure was opiate-negative urine specimens (thrice weekly urinalysis).

129 uctured exercise intervention either once or thrice weekly vs usual care (UC; advice only).

130 e urinary cocaine metabolite levels measured thrice weekly with a positive cutoff of 300 ng/mL.

131 injected subcutaneously with daily 1,25D or thrice weekly with FGF23 blocking antibody from 2 to 35

132 plied topical resiquimod gel 0.01% (twice or thrice weekly) or 0.05% (once or twice weekly) or vehicl

133 Delphinidin administration (2 mg, i.p. thrice weekly) to athymic nude mice implanted with PC3 c

134 2)) or repeated (four doses, 2 kJ/m(2)/dose, thrice weekly) UVR, emitted by Kodacel-filtered FS-40 su

135 ance (3 million units [MU]/m2 subcutaneously thrice weekly) was given until disease recurrence/progre

136 y) and endocervical swab specimens (obtained thrice weekly) were collected for HIV-1 RNA polymerase c

137 nously, weekly) or IFN (9 MIU subcutaneously thrice weekly) with bevacizumab (10 mg/kg intravenously,

138 ethambutol [E]) or the control regimen (RHZE thrice weekly).

139 two regimens, a low dose of FVIII (50 IU/Kg thrice weekly)or a high-dose (200 IU/kg daily

140 c healthy adults were prospectively followed thrice weekly, 60 days before, and 30 days after a RV16

141 Supervised urine samples were obtained thrice weekly, and self-reported cocaine and heroin use

142 lion units (MU) of interferon alfa-2b, given thrice weekly, and to determine whether higher doses of

143 h 10 or 20 mg/kg rapamycin intraperitoneally thrice weekly, beginning at 6 weeks of age.

144 d patients awaiting LT to a 6-week period of thrice weekly, supervised exercise on a static bike.

145 a (B-CLL), when given intravenously at 30 mg thrice weekly.

146 eatment regimen with SQ IL-10 given daily or thrice weekly.

147 pation received 300 microg/kg r-metHuNT-3 SC thrice weekly.

148 r CIA and mean severity scores were recorded thrice weekly.

149 iphosphate 5 mg; n = 45) or placebo (n = 45) thrice weekly.

150 schedule or to IFN-alpha 9 MU subcutaneously thrice weekly.

151 Urine was tested thrice weekly.

152 phase 2 (weeks 6-12), visits were reduced to thrice weekly.

153 Blood pressure was measured thrice weekly.

154 icients were developed for patients dialyzed thrice weekly: one for patients dialyzed after the long

155 Thrice-weekly (Monday/Wednesday/Friday) oral LAAM dose c

156 re assigned in a 2:2:1:1 ratio to either (1) thrice-weekly 3,000-IU cholecalciferol, (2) once-monthly

157 k, double-blind, placebo-controlled trial of thrice-weekly 500 mg oral azithromycin in adults with pe

158 tages 3-5 and hemoglobin <10.0 g/dl (1:1) to thrice-weekly 70-mg oral roxadustat or placebo.

159 Twice-weekly and thrice-weekly administration of ketamine at 0.5 mg/kg si

160 ents with relapsed CLL who were treated with thrice-weekly alemtuzumab for 12 weeks to assess the pot

161 Both thrice-weekly and once-monthly supplementation effective

162 ed patients with tuberculosis treated with a thrice-weekly antituberculosis regimen are at a higher r

163 f HIV and HAART on ARR among patients taking thrice-weekly antituberculosis therapy.

164 Previous efficacy studies, using thrice-weekly brief-pulse ECT, reported that high-dose (

165 d clinical trial in 1846 patients undergoing thrice-weekly dialysis, using a two-by-two factorial des

166 from that of extended weekly counseling and thrice-weekly dispensing.

167 e group was 29.2 +/- 4 percent, and the mean thrice-weekly dose of erythropoietin was 59 +/- 29 U per

168 eriment in which pregnant lizards were given thrice-weekly doses of a glucocorticoid hormone (cortico

169 stent with its prolonged duration of action, thrice-weekly dosing with SR-A3 led to a reduced tumour

170 alent tasks per week for participants in the thrice-weekly exercise group (both overall and per proto

171 d by -0.23% (95% CI, -0.48% to 0.01%) in the thrice-weekly exercise group and by -0.16% (95% CI, -0.4

172 .65% to -0.12%; P = .005) at 6 months in the thrice-weekly exercise group compared with UC.

173 ise group and 56 participants (47.1%) in the thrice-weekly exercise group were at least 50% adherent

174 ntion-to-treat analysis, participants in the thrice-weekly exercise group who attended at least 50% o

175 19 each to the UC, once-weekly exercise, and thrice-weekly exercise groups).

176 esistance and PP in thioacetamide (200mg/kg, thrice-weekly for 8 weeks)-induced cirrhotic rats.

177 amine and -5.7 (SD=10.2) for placebo; in the thrice-weekly groups, it was -17.7 (SD=7.3) for ketamine

178 t centers apply the standardized practice of thrice-weekly hemodialysis as soon as dialysis is introd

179 on a nondialysis day, patients with ESRD on thrice-weekly hemodialysis underwent overnight polysomno

180 Adults receiving thrice-weekly hemodialysis with predialysis hyperkalemia

181 nd catheter-related bacteremia compared with thrice-weekly heparin (heparin alone).

182 locking solution for catheters compared with thrice-weekly heparin.

183 Eight weeks of thrice-weekly i.p. injections (0.604 and 6.04 mug/kg of

184 nderwent uninephrectomy received 15 weeks of thrice-weekly i.p. treatment with 3 or 30 mg/kg LSKL pep

185 Outcomes with thrice-weekly in-center hemodialysis are poor.

186 Currently, thrice-weekly in-center hemodialysis for 3 to 5 hours pe

187 ive mortality in daily home hemodialysis and thrice-weekly in-center hemodialysis patients between 20

188 Many patients with kidney failure on thrice-weekly in-center hemodialysis reported worsening

189 summary, these data suggest that relative to thrice-weekly in-center hemodialysis, daily home hemodia

190 rs and cardiovascular outcomes compared with thrice-weekly in-center hemodialysis.

191 s induced in C57BL/6 (15 to 20 g) mice using thrice-weekly injections of carbon tetrachloride (CCl4)

192 s study evaluated the efficacy of twice- and thrice-weekly intravenous administration of ketamine in

193 20 loss, we investigated the hypothesis that thrice-weekly low-dose RTX (20 or 60 mg/m2) treatment fo

194 Thrice-weekly low-dose RTX may promote enhanced clearanc

195 percent) or enhanced medical management and thrice-weekly medication dispensing (39 percent) (P=0.64

196 weekly medication dispensing (48 percent) or thrice-weekly medication dispensing (43 percent) or enha

197 medical management and either once-weekly or thrice-weekly medication dispensing or enhanced medical

198 44 percent; standard medical management and thrice-weekly medication dispensing, 40 percent; and enh

199 percent; and enhanced medical management and thrice-weekly medication dispensing, 40 percent; P=0.82)

200 ispensing or enhanced medical management and thrice-weekly medication dispensing.

201 alciferol (equivalent to 9,000 IU/week), (3) thrice-weekly placebo, or (4) once-monthly placebo.

202 prospectively assessed CMV plasma DNAemia by thrice-weekly real-time polymerase chain reaction (PCR)

203 ty healthy young male participants completed thrice-weekly resistance exercise sessions for 10 weeks.

204 V/F (n = 12), and F/F (n = 12) treated with thrice-weekly rituximab (375 mg/m(2)) for 4 weeks to cor

205 Continuous IV FU and thrice-weekly SC rIFNalpha2b are an effective treatment,

206 sed level of dialysis on the hematocrit, the thrice-weekly schedule of dialysis was increased to rais

207 nalyzed the bacterial microbiome profiles of thrice-weekly stool samples from 20 intensively treated

208 A once-weekly structured exercise group, a thrice-weekly structured exercise group, or UC.

209 forts should focus on improving adherence to thrice-weekly structured exercise programs to meet exerc

210 therapeutic in most Indian patients taking a thrice-weekly TB regimen, and low rifampicin and pyrazin

211 Thrice-weekly therapy with IL-12 (1 mug) and 4D5 (1 mg/k

212 and ethambutol in the first 2 months, given thrice-weekly throughout the study along with HAART in o

213 Periodontal maintenance consisted of thrice-weekly toothbrushing the treated sites.

214 of patients with new pulmonary TB receiving thrice-weekly treatment in India.

215 ialysis (SHD) (all <65 yr of age, undergoing thrice-weekly treatments).

216 Results of thrice-weekly urine drug screens were analyzed using a g

217 es for evidence of cocaine abstinence during thrice-weekly urine testing was conducted.

218 Thrice-weekly urine toxicologic test results for cocaine

219 ase (twice-weekly, -12.2 [SD=12.8] on day 4; thrice-weekly, -14.0 [SD=12.5] on day 5).

220 ersion in the first 2 months compared with a thrice-weekly, 4-drug regimen in patients with newly dia

221 (EXERT-BC, EXERT-BCN, and EXERT-C) underwent thrice-weekly, dose-escalated resistance training for 3

222 , pyrazinamide, and ethambutol (given daily, thrice-weekly, or twice-weekly per the local tuberculosi

223 HIIT group was asked to complete 12 weeks of thrice-weekly, supervised aerobic sessions on a treadmil

224 Treatment of tuberculosis with short-course, thrice-weekly, supervised therapy in the setting of a de

225 grown from human donor corneas and passaged thrice were infected with a corneal isolate of Ad19 or m

226 Vaccination of healthy volunteers thrice with 533-mug HPV16 L2E7E6 at monthly intervals in

227 mice from body temperature to 41.5 degrees C thrice within 1.5 h, and showed the repeated formation o

228 2), and 4 schools in which students received thrice-yearly deworming (n = 970) with 500 mg generic me

229 Relative to no treatment, thrice-yearly deworming caused significant decreases in

230 deworming group and 0.45 (0.19, 1.08) in the thrice-yearly deworming group.

231 d -23.5 micromol/mol heme in the control and thrice-yearly deworming groups, respectively (P < 0.001)