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1  EAE when fed MBP but are not protected when thymectomized.
2 grafts eventually fail unless recipients are thymectomized.
3                              Recipients were thymectomized 3 wk before receiving an organ and/or tiss
4                                Chimeras were thymectomized 7 weeks later, and were either untreated o
5 e CD4, but not CD8, T cell population in the thymectomized adult mouse is dependent on the presence o
6 graft survival (>100 days) was achieved when thymectomized adult recipient mice were transplanted alo
7 Tx combined with donor BMC infusion in adult thymectomized, ALS-treated mice induced clonal deletion
8               Control chimeras that were not thymectomized also received anti-donor monoclonal antibo
9 ved in similar experiments in mice that were thymectomized and CD4 T cell depleted following complete
10 not in mice that were reconstituted and then thymectomized and CD8 T cell depleted.
11                                              Thymectomized and CD8 T cell-depleted mice that had been
12 from normal donors at preventing diabetes in thymectomized and irradiated PVG.RT1(u) rats.
13 ease development upon adoptive transfer into thymectomized and irradiated recipients.
14                 The donor hearts in both the thymectomized and non-thymectomized animals developed fl
15 s demonstrated a striking difference between thymectomized and nonthymectomized animals.
16                                However, both thymectomized and nonthymectomized MG patients had lower
17                                     Although thymectomized and sham-treated RMs manifested comparable
18                             BALB/c mice were thymectomized and T cell-depleted by injection of monocl
19                       Adult BALB/c mice were thymectomized and T-cell depleted using rat monoclonal a
20 dult irradiated C57BL/6 hosts that have been thymectomized and treated with anti-CD4 and CD8.
21                             BALB/c mice were thymectomized and treated with anti-CD8 antibody resulti
22                           DA recipients were thymectomized and treated with Ox8 and Ox38 murine monoc
23                               Euthymic, sham-thymectomized, and day-greater than or equal to +42 thym
24                                   Studies in thymectomized animals demonstrated that the profound CD8
25 nor hearts in both the thymectomized and non-thymectomized animals developed florid CAV.
26 at can be prevented by reconstitution of the thymectomized animals early in life with normal adult ly
27                    Nonthymectomized and sham thymectomized animals had a mild T cell infiltrate with
28                           Two of the day -21 thymectomized animals received a day 0 host-MHC matched
29                         Two of the partially thymectomized animals received irradiated (1000 cGy) as
30                                              Thymectomized animals receiving a kidney allograft alone
31                     CD3+ cells obtained from thymectomized animals treated with whole but not F(ab')2
32 as compared between partially and completely thymectomized animals.
33 ce was seen between partially and completely thymectomized animals.
34 f whole mAb, persisted for several months in thymectomized animals.
35         In contrast to untreated control and thymectomized, anti-Dd-treated chimeras, these euthymic
36                                   Adult mice thymectomized at birth and adult SCID mice did not devel
37 nt xenogeneic barrier in T/NK cell-depleted, thymectomized (ATX) B10 mice by grafting of fetal pig th
38 lation of mouse CD4+ T cells are achieved in thymectomized (ATX) B6 mice that receive T cell and natu
39                                              Thymectomized (ATX) IIKO mice showed the presence of a g
40 d by grafting fetal porcine thymus tissue to thymectomized (ATX) mice treated with natural killer (NK
41 /LIV) tissue to T cell and NK cell-depleted, thymectomized (ATX) mice.
42 (FP THY/LIV) to T cell and NK cell-depleted, thymectomized (ATX) mice.
43                                     In adult thymectomized (ATx) transgenic mice, only a small propor
44                   Lethally irradiated, adult-thymectomized (ATX), nontransgenic recipients reconstitu
45  pig thymus and liver tissue (FP THY/LIV) to thymectomized (ATX), T/NK cell-depleted mice.
46 cent of grafted nude mice and 10% of grafted thymectomized B6 mice develop a clinical illness resembl
47                                       In two thymectomized baboons that received porcine thymokidney
48 hymic emigrants as they were present in mice thymectomized before infection.
49                     Two miniature swine were thymectomized before thymic tissue transplantation, and
50               Three of these recipients were thymectomized before transplantation and accepted their
51                Therefore, adult Tg mice were thymectomized before treatment.
52 ame treatments on anergy of CD4 T cells from thymectomized, BM5-infected mice to determine whether th
53 ory-like T cells to oral Ag were examined in thymectomized BMC 60 days after i.p. immunization with O
54 ell progenitors in the marrow of euthymic or thymectomized but not nu/nu hosts.
55 ctivated spleen cells recreated rejection in thymectomized, but not euthymic, hosts, suggesting that
56 ic tolerance is achieved in T cell-depleted, thymectomized C57BL/6 (B6) mice and nude mice by graftin
57                                              Thymectomized C57BL/6 mice, treated with different combi
58    PVG.RT1 rat hearts were transplanted into thymectomized CD8 T-cell-depleted allogeneic (PVG.R8) or
59  addition, CD4+ CD25- cells transferred into thymectomized congenic mice converted to CD4+ CD25+ cell
60                                 d3Tx and non-thymectomized controls were infected with either GML str
61  were compared to the same parameters in non-thymectomized, cyclosporine-treated recipients bearing e
62                                              Thymectomized cynomolgus macaques underwent depletion wi
63 on autoimmune ovarian disease (AOD) in day 3 thymectomized (d3tx) mice and polyclonal T regs expressi
64 D) and oocyte autoantibody response of day 3-thymectomized (d3tx) mice were inhibited by continuous C
65 In autoimmune prostatitis (EAP) of the day-3 thymectomized (d3tx) mice, male Tregs suppressed EAP 3 t
66             Injection of anti-RT6.1 mAb into thymectomized DR and diabetes-prone-BB rats increased so
67 cell compartments from elderly, young adults thymectomized during early childhood, and HIV-1-infected
68  naive T cells from elderly and young adults thymectomized during early childhood, who are characteri
69 ctions in abrogating autoimmunities in 3-day thymectomized experimental mice.
70  course of HIV-1 infection in three patients thymectomized for myasthenia gravis and determined the e
71                       Euthymic (group A) and thymectomized (group B) Lewis recipients (LEW, RT1(1)) r
72 d into a recipient which had previously been thymectomized, had few circulating CD4-single positive c
73                     In contrast, none of the thymectomized heart/kidney recipients survived >100 days
74 4+ or CD8+ T cells expressing the Tg+/TCR in thymectomized hosts after bone marrow transplantation.
75 (3) CLPs protected thymus-bearing as well as thymectomized hosts from MCMV infection and attenuated d
76 d also induce tolerance if transplanted into thymectomized hosts, which, if true, would imply that th
77 e threshold for clinical GVHD, especially in thymectomized hosts.
78                                           In thymectomized immunodeficient mice receiving hHSPCs, hES
79  adoptively transferred into syngeneic adult thymectomized irradiated and bone marrow-reconstituted r
80 L development occurred efficiently in adult, thymectomized, irradiated C57BL/6J mice reconstituted wi
81 donors were capable of inducing tolerance in thymectomized juvenile hosts.
82 the euthymic rats and transient chimerism in thymectomized limb recipients.
83                In 17 nonthymectomized and 26 thymectomized MG patients studied at varying times after
84 splantation of DBA/2 donor spleen cells into thymectomized MHC-matched allogeneic BALB/c recipients i
85 eneic bone marrow transplantations (BMTs) on thymectomized mice and then vaccinated the mice with pep
86                                   Studies in thymectomized mice demonstrated that blockade of the cal
87 eration and cytokine production decreased in thymectomized mice even at wk 4 of infection, indicating
88                           Accordingly, adult thymectomized mice exhibit no reduction in the severity
89 pulation can be achieved in T cell-depleted, thymectomized mice grafted with xenogeneic porcine thymu
90 lation blockade resulted in tolerance, adult-thymectomized mice immunized for uveitis and treated wit
91 elopment of autoimmune disease in neonatally thymectomized mice is caused by the escape of self-react
92                   With the use of nude mice, thymectomized mice reconstituted with fetal liver cells,
93      Significantly, IL-7 administration into thymectomized mice resulted in patterns of decreased TRE
94  and skin xenograft survival in euthymic and thymectomized mice treated with combinations of DST, ant
95    In contrast, development in reconstituted thymectomized mice was heavily skewed toward TCR gammade
96                       We found that unprimed thymectomized mice were able to generate a primary respo
97 lying long-term graft survival, as recipient thymectomized mice were immunocompetent and harbor allor
98 , naive CD4 T cells derived from middle-aged thymectomized mice were longer-lived in vivo, and their
99 n of the IL-6(-/-) knockout, irradiated, and thymectomized mice with murine recombinant IL-6 restores
100 dditional studies carried on thymic T cells, thymectomized mice, and young T transferred cells into R
101        These effects were also seen in young thymectomized mice, consistent with the role of the thym
102                                           In thymectomized mice, development of CD4+ 8- and CD4+ 8+ T
103                     In thymus-intact but not thymectomized mice, IGF-1 administration increased perip
104 ctious tolerance, as originally described in thymectomized mice, may be applied to euthymic rat recip
105 matched skin grafts, originally described in thymectomized mice, may be applied to the euthymic prime
106                                           In thymectomized mice, the numbers of naive, central memory
107 for DC differentiation, and are abrogated in thymectomized mice.
108  in the OVA-fed euthymic mice but not in the thymectomized mice.
109 ollowing IL-7 treatment in thymus-intact and thymectomized mice.
110  skin allografts to survive for >100 days in thymectomized mice.
111 ould only be achieved in euthymic and not in thymectomized miniature swine using this treatment regim
112 histocompatibility complex (MHC) mismatch in thymectomized miniature swine.
113                                     Finally, thymectomized mixed chimeras showed increased GVHD follo
114                            Monkeys that were thymectomized (n=3) and depleted recovered via homeostat
115                              Recipients were thymectomized on day -21 (n=5) or day 0 (n=3), or were l
116                     In contrast, all animals thymectomized on day -21 that did not receive thymocyte
117 came tolerant, animals that were euthymic or thymectomized on day 0, as well as recipients of day 0 h
118                            Female B6AF1 mice thymectomized on day 3 (d3tx) develop autoimmune ovarian
119 f organ-specific autoimmune diseases in mice thymectomized on day 3 of life (d3tx mice) can be preven
120                                      Animals thymectomized on days +8 and +21 did not undergo severe
121  compared between mice that were either sham thymectomized or thymectomized (Thx) at approximately 6
122                                     Of three thymectomized patients, one rapidly progressed to AIDS,
123 ve in lymphopenic hosts, such as elderly and thymectomized patients.
124                                          For thymectomized rats, the median survival time (MST) of li
125  to the "noninfectious" form of tolerance in thymectomized rats.
126 ografts earlier (POD 8, 22, 27) than the non-thymectomized recipients (POD 33,35,45,47,55).
127 afts survived 100 days, but developed CAV in thymectomized recipients and in those permanently deplet
128               In contrast, day -21 and day 0 thymectomized recipients demonstrated allograft dysfunct
129 omized, and day-greater than or equal to +42 thymectomized recipients demonstrated stable renal funct
130                  Results of experiments with thymectomized recipients demonstrated that an intact thy
131           Grafting of donor thymic tissue to thymectomized recipients is an alternative approach for
132 he same protocol did not induce tolerance in thymectomized recipients nor in recipients beyond the ag
133 ated class I disparate heart allografts, the thymectomized recipients rejected their allografts earli
134 survival and the development of CAV in these thymectomized recipients were compared to the same param
135 hout immunosuppression into two of the three thymectomized recipients, and one of the three euthymic
136      These renal allografts were accepted by thymectomized recipients, but rejected by the euthymic r
137 eceptor (TCR)+ T cells have been reported in thymectomized recipients, whether this represents clonal
138 one autoimmune disease over another in day 3 thymectomized recipients.
139  and transplant the composite allograft into thymectomized recipients.
140 ical controls consisted of euthymic and sham-thymectomized recipients.
141 ce to class I-disparate kidney allografts in thymectomized recipients.
142 mic grafts simultaneously with the kidney in thymectomized recipients.
143 nor-reactive host CD4 cells also occurred in thymectomized, similarly treated marrow recipients, demo
144                                              Thymectomized swine developed acute cellular rejection c
145 porcine thymus into the quadriceps muscle of thymectomized T cell-depleted pigs results in full recon
146                                     Although thymectomized, T cell-depleted normal mice usually remai
147                                  Grafting of thymectomized, T cell-depleted normal mice with xenogene
148 tal pig thymic and hematopoietic tissue into thymectomized, T cell-depleted, and natural killer-cell-
149                    TCR expression returns in thymectomized Tg mice 3 days after MBP feeding and then
150 ted here is the first definitive study using thymectomized (ThX) animals to directly evaluate the con
151  mice that were either sham thymectomized or thymectomized (Thx) at approximately 6 weeks of age.
152 ibility of restoring transplant tolerance to thymectomized (TMX) ACI recipients with concomitant adop
153 d IL-10 genes was diminished in euthymic and thymectomized tolerant hosts.
154 fferent genetic backgrounds, were surgically thymectomized (TxT) and analyzed or challenged 2 mo late
155                                 In addition, thymectomized Vbeta5 transgenic RAG reporter mice are us
156 proximately 3% of CD4(+)Vbeta5(+) T cells in thymectomized Vbeta5 transgenic reporter mice have under
157  peripheral T-cell expansion is increased in thymectomized versus thymus-bearing hosts after bone mar

 
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