ライフサイエンスコーパス: thymic epithelial cell

1 PO mRNA predominantly localized to medullary thymic epithelial cells.

2 class II was expressed by thymocytes than by thymic epithelial cells.

3 le for MHC II ubiquitination specifically in thymic epithelial cells.

4 s can be selected on either hematopoietic or thymic epithelial cells.

5 expansion of early thymocyte progenitors and thymic epithelial cells.

6 in the self-antigen expression in medullary thymic epithelial cells.

7 thymocytes, early thymocyte progenitors, and thymic epithelial cells.

8 tion of this, BTN1A1 protein was detected in thymic epithelial cells.

9 quantitative expression of insulin in human thymic epithelial cells.

10 gher insulin expression than class I VNTR in thymic epithelial cells.

11 better define the heterogeneity of medullary thymic epithelial cells.

12 tissue-specific antigens is impaired only in thymic epithelial cells.

13 progenitor pool affects the number of mature thymic epithelial cells.

14 mily members in the development of medullary thymic epithelial cells.

15 n a manner that depends on AIRE(+) medullary thymic epithelial cells.

16 y for the differentiation and maintenance of thymic epithelial cells.

17 ll Ag receptors (TCR) to bind MHC ligands on thymic epithelial cells.

18 ping T cells encounter antigens expressed by thymic epithelial cells.

19 ited P-TEFb to target promoters in medullary thymic epithelial cells.

20 neage, whereas there is no role for Foxp3 in thymic epithelial cells.

21 progenitor cells but without deletion among thymic epithelial cells.

22 a developmental basis for TSA expression by thymic epithelial cells.

23 ions and MHC class II expression on cortical thymic epithelial cells.

24 , in particular dendritic cells and cortical thymic epithelial cells.

25 on the interaction of T cell precursors with thymic epithelial cells.

26 ve selection as a result of interaction with thymic epithelial cells.

27 blasts, myocardial endothelium, and cortical thymic epithelial cells.

28 idence of a single endodermal origin for all thymic epithelial cells.

29 roliferation and differentiation of immature thymic epithelial cells.

30 essed on placental endothelium and medullary thymic epithelial cells.

31 lex class II molecules expressed on cortical thymic epithelial cells.

32 bound peptide ligands presented by cortical thymic epithelial cells.

33 creased death and decreased proliferation of thymic epithelial cells.

34 d to B cells, dendritic cells, and medullary thymic epithelial cells.

35 ides bound to the MHC molecules expressed by thymic epithelial cells.

36 a stage that just precedes its detection in thymic epithelial cells.

37 presented by hematopoietic cells rather than thymic epithelial cells.

38 type cyclin produces a distinct phenotype in thymic epithelial cells.

39 pends on interactions between thymocytes and thymic epithelial cells.

40 cell receptor and MHC molecules expressed on thymic epithelial cells.

41 tical thymic epithelial cells, and medullary thymic epithelial cells.

42 a interaction with self-ligands displayed on thymic epithelial cells.

43 earliest thymocyte progenitors and cortical thymic epithelial cells.

44 tissue-restricted self-antigens in medullary thymic epithelial cells.

45 ical for the activation of INS-VNTR in human thymic epithelial cells.

46 stimulatory ligands (Dll4, Il7, and Vegf) by thymic epithelial cells.

47 ption factor which is expressed in medullary thymic epithelial cells.

48 particularly in keratinocytes and medullary thymic epithelial cells.

49 hematopoietic cells, such as AIRE-expressing thymic epithelial cells.

50 atients with APECED, especially in medullary thymic epithelial cells.

51 xpression of tissue-restricted Ags (TRAs) in thymic epithelial cells.

52 B7-expressing dendritic cells, B cells, and thymic epithelial cells.

53 d for the interaction between thymocytes and thymic epithelial cells.

54 and autoimmune regulator-positive medullary thymic epithelial cells, a key process for central toler

55 of autoimmune receptor-expressing medullary thymic epithelial cells (Aire1 mTEC) and a decrease in t

56 Deletion of TRAF3 in thymic epithelial cells allowed RelB-dependent developme

57 sed expression of tissue-specific Ags in the thymic epithelial cells and defective Ag presentation; h

58 study that increased MHC I up-regulation on thymic epithelial cells and double-positive CD3(-/int)CD

59 Expressed only by thymic epithelial cells and epidermal keratinocytes, Ski

60 sue culture system of thymic nodules wherein thymic epithelial cells and fibroblasts were grown in no

61 s preferentially damaged recipient medullary thymic epithelial cells and impaired negative selection,

62 tant role in interactions of thymocytes with thymic epithelial cells and in mature T cell interaction

63 nsplantation (allo-BMT) recipients, supports thymic epithelial cells and increases thymic output of n

64 vealed prominent cytosolic immunostaining in thymic epithelial cells and lymph node dendritic cells b

65 or thymic epithelial cell lineages--cortical thymic epithelial cells and medullary thymic epithelial

66 IL-22, which signaled through thymic epithelial cells and promoted their proliferation

67 n-like (Btnl) gene expressed specifically by thymic epithelial cells and suprabasal keratinocytes.

68 x class II (MHCII) is regulated similarly to thymic epithelial cells and that MHCII(+) ILC3s directly

69 IL-21 is produced by thymic epithelial cells and the IL-21 receptor-alpha is

70 th the highest levels of HLA-DQ8 on cortical thymic epithelial cells and the largest numbers of CD4 T

71 of respiratory TSA by an organized subset of thymic epithelial cells and the phenotypic resemblance o

72 cific serine protease (TSSP) is expressed by thymic epithelial cells and thymic dendritic cells (DCs)

73 tative serine protease expressed by cortical thymic epithelial cells and thymic dendritic cells, may

74 f NF-kappaB2 in the development of medullary thymic epithelial cells and, thus, the control of self-t

75 iates invariant chain processing in cortical thymic epithelial cells, and animals of the I-A(b) haplo

76 equires Skint-1 expression on the surface of thymic epithelial cells, and depends upon specific resid

77 in organ-specific self-antigens in medullary thymic epithelial cells, and has a role in the negative

78 urface of B cells, dendritic cells, cortical thymic epithelial cells, and medullary thymic epithelial

79 teraction with its ligand CXCL12 on cortical thymic epithelial cells, and that disruption of CXCR4-CX

80 Skint-1 is expressed by medullary thymic epithelial cells, and unlike lipid-CD1 complexes,

81 his observation indicates that MHC class II+ thymic epithelial cells are both necessary and sufficien

82 Previous studies suggest that thymic epithelial cells are crucial for the positive sel

83 s that regulate the development of medullary thymic epithelial cells are not fully understood.

84 Thymic epithelial cells are uniquely efficient in mediat

85 echanisms regulating development of immature thymic epithelial cells are unknown.

86 howed that the TTC7A protein is expressed in thymic epithelial cells, as well as in thymocytes.

87 t been fully evaluated, H2-O is expressed by thymic epithelial cells, B cells, and dendritic cells (D

88 lecule expressed in association with H2-M in thymic epithelial cells, B lymphocytes, and primary dend

89 E) critical for expression of Foxn1 in mouse thymic epithelial cells but dispensable for expression i

90 (+) readily acquired MHC class I and II from thymic epithelial cells but plasmacytoid DC were less ef

91 First, we increase medullary thymic epithelial cells by using mice lacking osteoprote

92 o the suggestion that local GC production by thymic epithelial cells, by opposing TCR signaling for a

93 These data suggest that TSLP expressed by thymic epithelial cells can activate mDCs and pDCs to po

94 MHC class II-expressing thymocytes and thymic epithelial cells can mediate CD4 T-cell selection

95 c mice, we provide qualitative evidence that thymic epithelial cells can transition to mesenchymal ce

96 ter system, CD4 T cells that are selected by thymic epithelial cells cannot transcribe the IL-4 repor

97 ese surprising findings suggest that, unlike thymic epithelial cells, cortical thymocytes can provide

98 The cortical and medullary thymic epithelial cell (cTEC and mTEC) lineages are esse

99 ic regions, where interactions with cortical thymic epithelial cell (cTEC) and medullary thymic epith

100 ucidated, the signals that regulate cortical thymic epithelial cell (cTEC) homeostasis remain elusive

101 e protease expressed exclusively in cortical thymic epithelial cells (cTEC) of the thymus, suggesting

102 Cortical thymic epithelial cells (CTEC) present self-peptide self

103 Cortical thymic epithelial cells (cTECs) express a unique thymopr

104 sis is through direct inhibition in cortical thymic epithelial cells (cTECs) of Delta-like 4 (Dll4),

105 Cortical thymic epithelial cells (cTECs) regulate T cell lineage

106 be necessary for Ii degradation in cortical thymic epithelial cells (cTECs), but not in bone marrow

107 ominance of immature thymocytes and cortical thymic epithelial cells (cTECs).

108 of B- and T-cell differentiation blocks and thymic epithelial cell defects, and induced robust cellu

109 ional programs were determined by Skint-1, a thymic epithelial cell determinant.

110 nscriptional regulatory pathway required for thymic epithelial cell development and define multiple r

111 Pax1, act synergistically to cause defective thymic epithelial cell development, resulting in thymic

112 demonstrated that loss of H2-O expression in thymic epithelial cells did not induce ANAs, and that la

113 t, deletion of a conditional Foxp3 allele in thymic epithelial cells did not result in detectable cha

114 allele of the nude gene that causes arrested thymic epithelial cell differentiation and abnormal thym

115 ption factors and plays an important role in thymic epithelial cell differentiation and development.

116 Foxn1Delta/Delta mutants have a block in thymic epithelial cell differentiation at an intermediat

117 Thymic epithelial cell differentiation, growth and funct

118 cell development as efficiently as cortical thymic epithelial cells do.

119 Mice deficient in Chd4 specifically in thymic epithelial cells exhibited autoimmune phenotypes,

120 Human and murine B cells and thymic epithelial cells express DO, while monocytes/macr

121 Both cystic and conventional medullary thymic epithelial cells express these TRAs, as do extrat

122 Thymic epithelial cells expressed an LRRC8A ligand that

123 Medullary thymic epithelial cells expressing the Aire gene play a

124 Strikingly, medullary thymic epithelial cells expressing the autoimmune regula

125 ched, particularly in neonates, in medullary thymic epithelial cells expressing the autoimmune regula

126 Thymic epithelial cell expression of CD83 is also necess

127 In addition to the proliferative block, most thymic epithelial cells fail to progress from an immatur

128 Injection of thymic epithelial cells from normal BALB/c mice into fet

129 nctioning in clinical certain contexts where thymic epithelial cell function is perturbed.

130 Medullary thymic epithelial cells function as antigen-presenting c

131 differentiation of Aire-expressing medullary thymic epithelial cells have been defined.

132 r hypomorphic Rag mutations while preserving thymic epithelial cell homeostasis.

133 no evidence that TSAs presented by medullary thymic epithelial cells in Aire+TCRmini mice are often r

134 e IA-IE expression on cortical and medullary thymic epithelial cells in an IFN-gamma-dependent manner

135 that in wild-type mice, suggesting cortical thymic epithelial cells in cathepsin L knockout mice exp

136 e selection, including the role of medullary thymic epithelial cells in displaying tissue specific an

137 rowth factor (KGF) has been shown to protect thymic epithelial cells in mice.

138 when presented to DP thymocytes by cortical thymic epithelial cells in reaggregate cultures, rather

139 We have evaluated a subset of thymic epithelial cells in the murine thymus that displa

140 olocalize with dendritic cells and medullary thymic epithelial cells in the thymic medulla.

141 plasia is caused by reduced proliferation of thymic epithelial cells in the thymus primordium.

142 o be improved by coimplantation of recipient thymic epithelial cells in the thymus xenograft.

143 Thymic epithelial cells in these mutants have reduced ab

144 of transcription in the nucleus of medullary thymic epithelial cells in vivo.

145 In contrast, differentiation of immature thymic epithelial cells, including acquisition of marker

146 opiridol were reduced by Hnrnpl knockdown in thymic epithelial cells, independently of their dependen

147 2 expression is a common feature of cortical thymic epithelial cells, indicating widespread availabil

148 on (CR) can slow thymic aging by maintaining thymic epithelial cell integrity and reducing the genera

149 g, whereas the function of individual mature thymic epithelial cells is compromised only modestly.

150 encoding tissue-specific antigens (TSAs) by thymic epithelial cells is critical for this process and

151 we could show in vivo that NIK signaling in thymic epithelial cells is essential for the thymic hard

152 The display of self-antigens by thymic epithelial cells is key to inducing tolerance in

153 receptor (TCR) transgenic thymocytes and the thymic epithelial cell line ANV indicated that low conce

154 A thymic epithelial cell line transfected with I-Ek was us

155 AIRE nuclear localization in the human thymic epithelial cell line was disrupted by mutations i

156 d antigens in both intact thymi and cultured thymic epithelial cell line.

157 the developmental pathways of the two major thymic epithelial cell lineages--cortical thymic epithel

158 In both medullary and cortical thymic epithelial cell lines transduced with TLP, the pr

159 s and in a nurse cell line, but not in other thymic epithelial cell lines, while the short form was m

160 at IFN-alpha-mediated MHC I up-regulation on thymic epithelial cells may lead to high avidity interac

161 pressing BM-derived dendritic cells, but not thymic epithelial cells, mediate the efficient negative

162 PRRSV-induced autophagy in thymic epithelial cells modulates the development of T c

163 regulator classically expressed in medullary thymic epithelial cells, monocytes, macrophages, and den

164 Previous studies show that medullary thymic epithelial cell (mTEC) development involves hemop

165 in T cell tolerance by regulating medullary thymic epithelial cell (mTEC) development.

166 Here we examine medullary thymic epithelial cell (mTEC) heterogeneity and its infl

167 minal differentiation model of the medullary thymic epithelial cell (mTEC) lineage from immature MHC

168 molecular mediators that stimulate medullary thymic epithelial cell (mTEC) maturation are partially e

169 branching structure that contains medullary thymic epithelial cell (mTEC) networks to support negati

170 thymic epithelial cell (cTEC) and medullary thymic epithelial cell (mTEC) subsets take place.

171 ve previously reported that mature medullary thymic epithelial cells (mTEC(high)) expressing the auto

172 antigens (TRA), which is in mature medullary thymic epithelial cells (mTEC(high)) partly controlled b

173 Both medullary thymic epithelial cells (mTEC) and dendritic cells (DC)

174 o induce central T-cell tolerance, medullary thymic epithelial cells (mTEC) collectively express most

175 Medullary thymic epithelial cells (mTEC) contribute to the develop

176 velopmental pathways that generate medullary thymic epithelial cells (mTEC) from their immature proge

177 In the thymus, medullary thymic epithelial cells (mTEC) regulate T cell tolerance

178 ing T cells is highly dependent on medullary thymic epithelial cells (mTEC), and mTEC development in

179 able of mediating deletion, namely medullary thymic epithelial cells (mTECs) and dendritic cells, whe

180 s expressed on Aire(-) and Aire(+) medullary thymic epithelial cells (mTECs) and on dendritic cells (

181 6 transcripts were absent in mouse medullary thymic epithelial cells (mTECs) and peripheral lymphoid

182 scription of a battery of genes in medullary thymic epithelial cells (mTECs) and, consequently, negat

183 Medullary thymic epithelial cells (mTECs) are critical in establis

184 n this study, we reveal a role for medullary thymic epithelial cells (mTECs) during iNKT cell develop

185 immune regulator (Aire)-expressing medullary thymic epithelial cells (mTECs) during the embryonic-neo

186 Medullary thymic epithelial cells (mTECs) eliminate self-reactive

187 Medullary thymic epithelial cells (mTECs) express a broad spectrum

188 of peripherally restricted Ags by medullary thymic epithelial cells (mTECs) is associated with negat

189 restricted self antigens (TRAs) in medullary thymic epithelial cells (mTECs) is essential for the ind

190 restricted self-antigens (TRAs) in medullary thymic epithelial cells (mTECs) is essential to safeguar

191 tissue-specific antigens (TSAs) by medullary thymic epithelial cells (Mtecs) leads to deletion of aut

192 bone marrow (BM)-derived APCs and medullary thymic epithelial cells (mTECs) on the conventional and

193 Medullary thymic epithelial cells (mTECs) play a critical role in

194 Aire-expressing medullary thymic epithelial cells (mTECs) play a key role in preve

195 Medullary thymic epithelial cells (mTECs) play an essential role i

196 Medullary thymic epithelial cells (mTECs) play an important role i

197 how that bone marrow (BM) APCs and medullary thymic epithelial cells (mTECs) played nonoverlapping ro

198 of tissue-restricted Ags (TRAs) by medullary thymic epithelial cells (mTECs) plays an essential role

199 immune regulator (Aire)-expressing medullary thymic epithelial cells (mTECs) provide a spectrum of ti

200 tions in terminally differentiated medullary thymic epithelial cells (MTECs) to derepress the express

201 In medullary thymic epithelial cells (mTECs), the Autoimmune regulato

202 ntral tolerance mechanisms involve medullary thymic epithelial cells (mTECs), which use endogenously

203 e in developing T cells depends on medullary thymic epithelial cells (mTECs), whose development, in t

204 pecifically in the Aire-expressing medullary thymic epithelial cells (mTECs), without affecting its e

205 rtical thymic epithelial cells and medullary thymic epithelial cells (mTECs)--are yet to be developed

206 ng, autoimmune regulator (AIRE)(+) medullary thymic epithelial cells (mTECs).

207 e in the absence of RelB-dependent medullary thymic epithelial cells (mTECs).

208 In contrast, the rate of decline in thymic epithelial cell numbers with age was radiation-se

209 l MHC class II-positive cells, restricted to thymic epithelial cells, or restricted to B cells, dendr

210 Age-associated decreases in thymic-epithelial cell ( P < 0.01) and thymocyte markers

211 hymus involutes, reduction in thymocytes and thymic epithelial cells precede the emergence of mature

212 Perhaps surprisingly, thymic epithelial cells produce glucocorticoids, and bas

213 ively induced in vitro to differentiate into thymic epithelial cell progenitors (TEPs).

214 ular, mesenchymal cells are shown to mediate thymic epithelial cell proliferation through their provi

215 Thymic epithelial cells provide unique cues for the life

216 Ps differentiate into cortical and medullary thymic epithelial cells, reconstitute the normal thymic

217 er model has suggested that this property of thymic epithelial cells reflects transcriptional activit

218 eletion of Rank (also known as Tnfrsf11a) in thymic epithelial cells results in impaired thymic invol

219 miRNA in the maintenance and function of the thymic epithelial cell scaffold and establish a novel me

220 rvical thymi (pCT) express low levels of the thymic epithelial cell-specific transcription factor FOX

221 eport that germinal center B lymphocytes and thymic epithelial cells strongly express one of the RGS

222 omoting self-antigen expression in medullary thymic epithelial cells, such that developing T cells th

223 strate that endogenous RA signaling promotes thymic epithelial cell (TEC) cell-cycle exit and restric

224 ous tissue-specific antigens (TSAs) in human thymic epithelial cell (TEC) cultures.

225 Thymocyte and thymic epithelial cell (TEC) development are interdepend

226 jor source of Wnt ligands and to what extent thymic epithelial cell (TEC) development is dependent on

227 x N1 (Foxn1) protein is the key regulator of thymic epithelial cell (TEC) development, yet how Foxn1

228 FOXN1), a transcription factor essential for thymic epithelial cell (TEC) differentiation.

229 s, radiation exposure, and steroids, impairs thymic epithelial cell (TEC) functions and induces the p

230 Postnatal thymic epithelial cell (TEC) homeostatic defect- or natu

231 Myeloablative conditioning results in thymic epithelial cell (TEC) injury, slow T-cell reconst

232 bone marrow transplantation (BMT) results in thymic epithelial cell (TEC) injury, T-cell immune defic

233 or FoxN1 is essential for differentiation of thymic epithelial cell (TEC) progenitors during thymic o

234 red for differentiation and proliferation of thymic epithelial cell (TEC) progenitors.

235 ene (Tbata; also known as SPATIAL) regulates thymic epithelial cell (TEC) proliferation and thymus si

236 Progress in our understanding of thymic epithelial cell (TEC) renewal and homeostasis is

237 Using an allelic series of the thymic epithelial cell (TEC) specific transcription fact

238 eactivity, which was secondary to changes in thymic epithelial cell (TEC) stimuli that drive thymocyt

239 that precursors within the keratin (K) 8+5+ thymic epithelial cell (TEC) subset generate the major c

240 Recently, diminished expression of the thymic epithelial cell (TEC)-specific transcription fact

241 blation of ghrelin and GHSR leads to loss of thymic epithelial cells (TEC) and an increase in adipoge

242 Interactions between thymic epithelial cells (TEC) and developing thymocytes

243 drogen withdrawal by proliferation of UEA(+) thymic epithelial cells (TEC) and increased TEC producti

244 e thymic epithelium and is required to prime thymic epithelial cells (TEC) for effective Treg inducti

245 In this study, we demonstrated that human thymic epithelial cells (TEC) inhibit NK cell developmen

246 Promiscuous gene expression (PGE) by thymic epithelial cells (TEC) is essential for generatin

247 ells, which discordant studies identified as thymic epithelial cells (TEC) or CD11c+ dendritic cells

248 expression of tissue-restricted Ags (TRA) by thymic epithelial cells (TEC).

249 is accompanied by a decline in the number of thymic epithelial cells (TECs) and a severely restricted

250 nal CD8(+) T cells are primarily selected on thymic epithelial cells (TECs) and certain innate T cell

251 reby inhibiting IL-22-mediated protection of thymic epithelial cells (TECs) and impairing recovery of

252 (ephrins) are expressed both on T cells and thymic epithelial cells (TECs) and play a role in defini

253 FOXN1 gene dosage effect on the function of thymic epithelial cells (TECs) and thymopoiesis and post

254 Although thymic epithelial cells (TECs) are crucial for thymopoie

255 Thymic epithelial cells (TECs) are required for T cell m

256 damage to the interleukin 7 (IL-7)-producing thymic epithelial cells (TECs) by irradiation and chemot

257 ing human pluripotent stem cells to generate thymic epithelial cells (TECs) capable of supporting T c

258 e characterize the role of macroautophagy in thymic epithelial cells (TECs) for negative selection.

259 om NCC-derived mesenchyme or differentiating thymic epithelial cells (TECs) had no effects on thymus-

260 Thymic epithelial cells (TECs) help orchestrate thymopoi

261 Thymic epithelial cells (TECs) in adult mice have been c

262 ffects on T-cell precursors, thymocytes, and thymic epithelial cells (TECs) in normal and genetically

263 role of hematopoietic-derived APCs (HCs) and thymic epithelial cells (TECs) in Treg selection, we con

264 The importance of thymic epithelial cells (TECs) is evidenced by clear lin

265 Thymic epithelial cells (TECs) provide crucial microenvi

266 toimmunity is largely prevented by medullary thymic epithelial cells (TECs) through their expression

267 We identified IL-7-expressing thymic epithelial cells (TECs) throughout ontogeny and i

268 we find that resupplying young, engraftable thymic epithelial cells (TECs) to a middle-aged or defec

269 require LXRalphabeta for cholesterol efflux, thymic epithelial cells (TECs) use LXRalphabeta for self

270 ing bone marrow chimeras, GILT expression in thymic epithelial cells (TECs), but not hematopoietic ce

271 Although SPL is robustly expressed in thymic epithelial cells (TECs), in this study, we show t

272 estrogens have strong regulatory effects on thymic epithelial cells (TECs), inducing a decreased pro

273 originates from the expansion of functional thymic epithelial cells (TECs).

274 ty interaction with MHC class I molecules on thymic epithelial cells (TECs).

275 mocyte development require interactions with thymic epithelial cells (TECs).

276 aged mice by restoration of the function of thymic epithelial cells (TECs).

277 on cultured human thymic stroma, especially thymic epithelial cells (TECs).

278 se results were confirmed in purified murine thymic epithelial cells (TECs).

279 iated effects on homeostasis and function of thymic epithelial cells that affect thymic selection pro

280 reduction in the number of mature medullary thymic epithelial cells that express CD80 and bind the l

281 to regulate the differentiation of immature thymic epithelial cells, thereby affecting tissue-restri

282 ve been done with populations of dissociated thymic epithelial cells; therefore, there is little info

283 tors into preimmune sheep fetuses transduces thymic epithelial cells thought to present antigen and t

284 ally affect human insulin gene expression in thymic epithelial cells through INS-VNTR and subsequentl

285 -regulation of ICA69 expression in medullary thymic epithelial cells, thus providing a novel mechanis

286 Thus we conclude that the ability of thymic epithelial cells to support positive selection do

287 ce MHC-self peptide complexes from medullary thymic epithelial cells to thymic DC.

288 ional deletion of Traf6 expression in murine thymic epithelial cells (Traf6DeltaTEC mice) showed a su

289 pment depends critically on several distinct thymic epithelial cell types that are organized into two

290 ifferent individual K(b) binding peptides in thymic epithelial cells under the control of the human k

291 In addition to their differentiation, thymic epithelial cells undergo cellular expansion to en

292 he predominant isozyme expressed in cortical thymic epithelial cells was COX-1, while COX-2 predomina

293 tal numbers of EpCAM+ MHC II+ and MHC II(hi) thymic epithelial cells were higher in young and old Fox

294 n to T reg cells, Foxp3 is also expressed in thymic epithelial cells where it is involved in regulati

295 une regulator), which is highly expressed in thymic epithelial cells, where it is known to play a key

296 unctions within stroma to generate medullary thymic epithelial cells, which are essential for negativ

297 Unlike medullary thymic epithelial cells, which express and present perip

298 mmune regulator-expressing, mature medullary thymic epithelial cells, which play a pivotal role in ne

299 n of many tissue-specific genes in medullary thymic epithelial cells, which plays an important role i

300 ifferential insulin gene expression in human thymic epithelial cells, which should have profound effe

301 en in reaggregates of purified MHC class II+ thymic epithelial cells, while CD4+ and CD8+ cells gener