ライフサイエンスコーパス: thymine

1 e de novo biosynthesis of the DNA nucleotide thymine.

2 racil is reduced under similar conditions to thymine.

3 le blue redox probe conjugated to a modified thymine.

4 redox active probe conjugated to a modified thymine.

5 bound by the TALE (the N0 base) should be a thymine.

6 dation of A/T-rich DNA leads to mutations at thymine.

7 (dsDNA), it forms three hydrogen bonds with thymine.

8 s, and the third containing both adenine and thymine.

9 ractions is adenine > cytosine >/= guanine > thymine).1 Since the degree of gold-DNA affinity interac

10 ntrinsic preference for cytosine preceded by thymine (5'-TC) in single-stranded DNA substrates, where

11 he methyl group of 5-methylcytosine (5mC) or thymine (5-methyluracil).

12 status of two DNA bases 5-methylcytosine and thymine (5-methyluracil).

13 osine (G-C) base pair by zero-to-six adenine-thymine (A-T) base pairs has been investigated.

14 amination of 5-methylcytosine (mC) generates thymine, a canonical DNA base, presenting a challenge fo

15 Methyl groups of thymine acts as a steric block, relocating spermine from

16 ences containing 10 deoxy-ribonucleotides of thymine, adenine, cytosine, or guanine results in the gr

17 asured by the slide parameter in the central thymine-adenine base pairs; we also detect 'dynamic' def

18 The resulting thymine allylic radical was suggested to take an H atom

19 ssion to form a repaired 5'-thymine and a 3'-thymine allylic radical.

20 The thymine analog 5-chlorouridine, first reported in the 19

21 d established cell-tracking methods based on thymine analog cell labeling and developed tailored math

22 glycosylation step utilized en route to the thymine analogue clearly suggests the absence of anchime

23 nd 5-hydroxymethylcytosine (5hmC) as well as thymine and 5-hydroxymethyluracil (i.e., the deamination

24 ndergoes beta scission to form a repaired 5'-thymine and a 3'-thymine allylic radical.

25 s well as their 2',3'-dideoxy analogues with thymine and adenine nucleobases.

26 We also show that cleavage of thymidine to thymine and deoxyribose-1-phosphate by the host thymidin

27 Using this route, we synthesized the thymine and guanine 2'-NH2-TNA nucleosides in seven step

28 For adenine-thymine and guanine-cytosine base pairs, we review recen

29 s on pyrimidine 5' methyl groups provided by thymine and requires adjacent guanines and a correctly o

30 for the generation and isolation of various thymine and thymidine 5,6-epoxides from the correspondin

31 d photoelectron spectroscopy is performed on thymine and thymidine in aqueous solution to study the e

32 ely 20%) for guanine over adenine, cytosine, thymine and uracil, but this selectivity is extraordinar

33 to prepare high-purity 4-arm PEG-T(20) (T = thymine) and 4-arm PEG-A(20) building blocks in multigra

34 demonstrate that SLC25A33 transports uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosp

35 n-butylamine, adenosine, cytosine, guanine, thymine, and l-arginine.

36 would provide a preference for cytosine over thymine, and the latter one could explain the E446D pref

37 dhT) within TpT, a reaction likely involving thymine anion radicals.

38 atic rings and attached methyl groups (as on thymine) are particularly favorable, as previously obser

39 initially located on adenines, localizes on thymine as the proton is lost from the methyl group, dem

40 n bands for phenylalanine at 1001 cm(-1) and thymine at 747 cm(-1) Raman bands), were used to quantif

41 demonstrate the concept using the nucleobase thymine at the oxygen K-edge, and unambiguously show tha

42 ned with mutating the continuous sequence of thymines at position 4 to cytosine or guanine significan

43 The AR9 nvRNAP requires uracils rather than thymines at specific conserved positions of late viral p

44 GapR interacts with adenine and thymine (AT)-rich chromosomal loci, associates with the

45 irions up to 0.7 mum in diameter and adenine-thymine (AT)-rich genomes of up to 1.25 Mb encoding a th

46 ransfer than its corresponding N3-protonated thymine base (14 kcal/mol).

47 find that short minimum loop length and the thymine base are two main factors that lead to high GQ f

48 tonated at N3, one-electron oxidation of the thymine base by Cl(2)(*-) at ca. 155 K results in format

49 cules at both ends of the CTG repeat induces thymine base flipping and DNA backbone deformation to fo

50 , calculations predict that the deprotonated thymine base has a lower energy barrier (ca. 6 kcal/mol)

51 At pHs ca. 9-10 where the thymine base is largely deprotonated at N3, one-electron

52 This study indicated that the canonical thymine base is the preferential base partner of methyla

53 5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomes of a dive

54 cinoma cells, the levels of both - 5fC and a thymine base modification, 5-hydroxymethyluracil, are co

55 showing that installation of a 2-aminopurine-thymine base pair at the cross-linking site produced hig

56 ytosine, isoguanine-isocytosine, and adenine-thymine base pairs.

57 of deuterium substitution at C5' and on the thymine base, that is, specifically employing [5',5"-D,D

58 ng more stability than an additional adenine-thymine base-pairing interaction, 2.7 kJmol(-1).

59 cular OH group transfer from C5 to C6 in the thymine base.

60 that upon photoexcitation form adducts with thymine bases.

61 iched with motifs consisting of a stretch of thymine bases.

62 share the feature that 5-methylcytosine and thymine both have a methyl group in the same position, 5

63 ay is converting unmethylated cytosines into thymines (BS conversion).

64 In addition, a thymine bulge is found between G8 and G9.

65 of peptides conjugated to the C5 position of thymine by human translesion synthesis polymerases leads

66 I-C base pairs (G = guanine, A = adenine, T= thymine, C = cytosine, I = inosine).

67 i stacking and an Au...O contact involving a thymine carbonyl group, resolving the ambiguity of conve

68 lfur substitution of a carbonyl group in the thymine chromophore at position 2 or 4 results in a sign

69 toms in the exocyclic carbonyl groups of the thymine chromophore by sulfur atoms results in a remarka

70 A due to the formation of the thymine-Hg(2+)-thymine complex, which holds the Hg(2+) ions in proximit

71 As a general trend, the thymine-containing compounds showed k(q) values higher t

72 atabase and molecular dynamics trajectory of thymine-containing oligomer.

73 converted targeted cytidines specifically to thymines, creating specific point mutations.

74 In the reactions, additional nucleobases (thymine, cytosine, adenine, or guanine) were attached to

75 culated the electronic excitation spectra of thymine, cytosine, and adenine stacked dimers with ab in

76 onates with the natural nucleobases adenine, thymine, cytosine, and guanosine has been performed.

77 ibacterial and chemotherapeutic drugs elicit thymine deficiency, a mechanistic understanding of this

78 Under these growth conditions, accelerated thymine depletion is the primary trigger of the processe

79 Thymine depletion-induced DNA replication stress leads t

80 intermediate metabolite for the synthesis of thymine-derived nucleotides.

81 nctional classes, which photo-reactivate the thymine dimer along different pathways.

82 lineC/C-C stretch vibrations) of cyclobutane thymine dimer and thymine dinucleotide radical anion, th

83 ms error-free bypass of the 8-oxoguanine and thymine dimer DNA lesions, though with a 10(3) and 10(2)

84 dark (1)npi* excited states does not lead to thymine dimer formation.

85 PL) repairs 5-thyminyl-5,6-dihydrothymine, a thymine dimer that is also called the spore photoproduct

86 A by converting two adjacent thymines into a thymine dimer which is potentially mutagenic, carcinogen

87 d in UV-irradiated bacterial endospores is a thymine dimer, 5-thyminyl-5,6-dihydrothymine, i.e., the

88 Cyclobutane thymine dimer, one of the major lesions in DNA formed by

89 ct lyase (SPL) repairs a covalent UV-induced thymine dimer, spore photoproduct (SP), in germinating e

90 The long debated question whether thymine dimerization after direct light excitation invol

91 s value is comparable to that of cyclobutane thymine dimers (the major UV-induced lesions) in genomic

92 The formation of cyclobutane thymine dimers is one of the most important DNA carcinog

93 de currents in osteoblasts, had no effect on thymine dimers on its own but prevented the 1,25(OH)(2)D

94 Thymine dimers were found at a potential of about 1.1 V

95 f <310 nm wavelength to photo-reactivate CPD thymine dimers within a substrate DNA.

96 IDS, at concentrations that had no effect on thymine dimers, blocked UVR-induced upregulation of p53.

97 oride currents help protect from UVR-induced thymine dimers, but further increases in p53 or reductio

98 ls against UVR-induced DNA damage, including thymine dimers, but the mechanism is unknown.

99 e 1,25(OH)(2)D(3)-induced protection against thymine dimers.

100 rations shown to block decreases in post-UVR thymine dimers.

101 esions, such as abasic sites and cyclobutane thymine dimers.

102 DNA damage (thymine dimers: T-T dimers) and vitamin D (25(OH)D) synt

103 vibrations) of cyclobutane thymine dimer and thymine dinucleotide radical anion, thymidylyl(3'-->5')t

104 excision of the latter oxidation products by thymine DNA (TDG) or Nei-like 1 (NEIL1) glycosylases fol

105 ipping assay to study damage search by human thymine DNA glycosylase (hTDG), which initiates BER of m

106 easoned that the base excision repair enzyme thymine DNA glycosylase (TDG) could be such a target for

107 can be modulated in the presence of TET and thymine DNA glycosylase (TDG) enzymes.

108 The mammalian thymine DNA glycosylase (TDG) excises the mismatched bas

109 Tet methylcytosine dioxygenase 2 (TET2), and Thymine DNA glycosylase (TDG) genes.

110 aC), with 5fC and 5caC subject to removal by thymine DNA glycosylase (TDG) in conjunction with base e

111 nd T:G mispair, and this step is followed by thymine DNA glycosylase (TDG) initiated base excision re

112 Thymine DNA glycosylase (TDG) initiates the repair of G.

113 Thymine DNA Glycosylase (TDG) is a base excision repair

114 Thymine DNA glycosylase (TDG) is an essential enzyme pla

115 Thymine DNA Glycosylase (TDG) performs essential functio

116 slocation (TET) enzymes (TET1/TET2/TET3) and thymine DNA glycosylase (TDG) play crucial roles in earl

117 g a panel of DNA demethylases, we found that thymine DNA glycosylase (TDG) up-regulated Wnt signaling

118 relationship between chromatin structure and thymine DNA glycosylase (TDG) using chemically defined n

119 oxylcytosine (caC), excision of fC or caC by thymine DNA glycosylase (TDG), and restoration of cytosi

120 oxylcytosine (caC), excision of fC or caC by thymine DNA glycosylase (TDG), and subsequent base excis

121 aC are selectively recognized and excised by thymine DNA glycosylase (TDG), leading to DNA demethylat

122 e bases are recognized by the monofunctional thymine DNA glycosylase (Tdg), which cleaves the glycosi

123 ollowed by replication-dependent dilution or thymine DNA glycosylase (TDG)-dependent base excision re

124 to cytosine through iterative oxidation and thymine DNA glycosylase (TDG)-mediated base excision rep

125 veral regulatory proteins, including p53 and thymine DNA glycosylase (TDG).

126 lcytosine (5fC)/5-carboxylcytosine (5caC) by thymine DNA glycosylase (TDG).

127 oxygenases and excision of oxidized bases by thymine DNA glycosylase (TDG).

128 s that themselves contribute to AML, such as thymine DNA glycosylase (TDG).

129 excise thymine from G.T mispairs, including thymine DNA glycosylase (TDG).

130 Thymine DNA glycosylase can further remove 5fC and 5caC,

131 Knockdown of thymine DNA glycosylase increased 5caC in genome, affect

132 rvation was paralleled by a compromised TDG (thymine DNA glycosylase) and TET1 (ten-eleven translocat

133 CadC, and 5-HmdU, may be cleaved from DNA by thymine DNA glycosylase, and subsequent action of base-e

134 regeneration-associated genes in a Tet3- and thymine DNA glycosylase-dependent fashion in DRG neurons

135 e delta but instead depends, in part, on the thymine DNA glycosylase.

136 paired to regenerate unmodified cytosines by thymine-DNA glycosylase (TDG) and base excision repair (

137 Thymine-DNA glycosylase (TDG) plays critical roles in DN

138 Many TET2- and thymine-DNA glycosylase (TDG)-dependent 5mC and 5hmC cha

139 epend on two additional uracil glycosylases, thymine-DNA glycosylase and SMUG1.

140 s not influenced by either UNG1/2, SMUG1, or thymine-DNA glycosylase knockdown, strongly suggesting t

141 n of UNG1/2 but not by knockdown of SMUG1 or thymine-DNA glycosylase uracil-DNA glycosylases, proving

142 Subsequent PCR converts DHU to thymine, enabling a C-to-T transition of 5mC and 5hmC.

143 lso show that a conserved Ala residue limits thymine excision by hindering nucleotide flipping.

144 als that TDG attains context specificity for thymine excision through modulation of nucleotide flippi

145 rved that A3G favors adenines, cytosines and thymines flanking the cytosine dinucleotide target in un

146 iated by the JBP1/2 enzymes that hydroxylate thymine, forming 5-hydroxymethyluracil (hmU).

147 th absence of -7T, the very highly conserved thymine found at the last position in -10 elements of pr

148 TDG preferentially removes thymine from DNA contexts in which cytosine methylation

149 are three types of glycosylases that excise thymine from G.T mispairs, including thymine DNA glycosy

150 Initiating base excision repair, TDG removes thymine from mutagenic G .: T mispairs caused by 5-methy

151 TDG removes thymine from mutagenic G.T mispairs arising from deamina

152 In contrast, the release of thymine from TpT was minor (<20%) and did not result in

153 cated that the population of WC-like guanine-thymine (G-T) mispairs depends on the environment, such

154 (T-Hg-T): in fact, Hg(2+) tends to bind two thymines, generating a T-Hg-T complex with a formation c

155 We show that TLS through the thymine glycol (TG) lesion, the most common oxidation pr

156 Here, we show that telomeric DNA containing thymine glycol (Tg), 8-oxo-7,8-dihydroguanine (8-oxoG),

157 dative DNA lesions, 8-oxoguanine (8oxoG) and thymine glycol (Tg), regulate the structural properties

158 capable of quantifying the rate of repair of thymine glycol in a variety of human cells with a high d

159 es RECQL1 on telomeric substrates containing thymine glycol, a replicative blocking lesion.

160 ves oxidized pyrimidines from DNA, including thymine glycol.

161 For guanine-adenine (GA), guanine-thymine (GT) and guanine-guanine (GG) mismatches, the se

162 Tgif1 (thymine-guanine-interacting factor 1) and Tgif2 repress

163 of this tract by adding adenines instead of thymines had similar effects, while the addition of othe

164 ich bacteria lose viability when deprived of thymine have been elusive for over half a century.

165 Based on a "thymine-Hg(2)(+)-thymine" mechanism and monitoring the s

166 Well-known examples include thymine-Hg(2+) interactions and Hg(2+)-activated DNAzyme

167 emical biosensor is developed by integrating thymine-Hg(2+)-thymine (T-Hg(2+)-T) base pairs for the h

168 By utilizing thymine-Hg(2+)-thymine (T-Hg(2+)-T) coordination chemist

169 ble-stranded DNA due to the formation of the thymine-Hg(2+)-thymine complex, which holds the Hg(2+) i

170 sensors through the formation of the complex Thymine-Hg-Thymine (T-Hg-T): in fact, Hg(2+) tends to bi

171 ement of the fluorine substituent with H6 of thymine, however, with a distance that is relatively lon

172 (4444)](+)) hydroxide with adenine (HAd) and thymine (HThy) led to hydrated salts of deprotonated ade

173 editors also convert cytosine to guanine or thymine in a narrow editing window (positions 5-7) and i

174 btained data, the main oxidation products of thymine in aqueous solution could most likely be identif

175 is not involved in the relaxation process of thymine in aqueous solution.

176 O-linked glucosylation of thymine in DNA (base J) is an important regulatory epige

177 or the Raman red shifts of phenylalanine and thymine in response to (13)C-labeling is proposed in thi

178 with significantly more cytosines mutated to thymine in the lagging-strand template (LGST) than in th

179 576 (R576) to interact, respectively, with a thymine in the minor groove, a phosphate group of DNA ba

180 thyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of th

181 n enzymes to catalyze iterative oxidation of thymine in trypanosome DNA.

182 anine cross-links with adjacent or nearby N3-thymines in DNA in the presence of O2.

183 g, and permanganate failed to detect exposed thymines in the loop regions.

184 Sequencing of the katA gene demonstrated a thymine insertion leading to a frameshift mutation and p

185 light damages DNA by converting two adjacent thymines into a thymine dimer which is potentially mutag

186 omoazanucleoside containing both adenine and thymine, is a left-handed helix formed through Watson-Cr

187 a small molecule, cyanuric acid, with three thymine-like faces, reprogrammes the assembly of unmodif

188 es has been used as a tool to populate upper thymine-like triplet states via intramolecular sensitiza

189 Enlarged W of thymine-limited thyA mutants growing at identical rates

190 Based on a "thymine-Hg(2)(+)-thymine" mechanism and monitoring the shift in the thres

191 e-pair steps with thymine versus uracil, the thymine methyl group tends to enhance the strength of th

192 ions, each featuring a tyrosine contacting a thymine methyl group.

193 the additional ZF interacts with a conserved thymine methyl group.

194 samples showed a high degree of cytosine to thymine mismatches, typical of post-mortem damage.

195 In this genus, another thymine modification, 5-(beta-glucopyranosyl) hydroxymet

196 We studied the distribution of thymine modifications in the Leishmania major genome by

197 o-chemical properties of DNA produced by the thymine modifications may have implications for recognit

198 te nanopores, short DNA fragments containing thymine modifications were found to exhibit distinct, re

199 hemical method to selectively tag and enrich thymine modifications, 5-formyluracil (5-fU) and 5-hydro

200 ns were chromatographically determined using thymine-modified complements that increase the overall c

201 to the closely related photoaddition of two thymine moieties within the DNA.

202 ng two adenine molecules, the other with two thymine moieties, and the third containing both adenine

203 ntaining either an abasic site or a psoralen-thymine monoadduct.

204 While the natural thymine monomers owe their high degree of photostability

205 A cytosine to thymine mutation at nucleotide 654 of human beta-globin

206 e also show that the predominant cytosine-to-thymine mutations observed in single-cell genomics often

207 chor with a reporter fluorophore on the same thymine nucleobase.

208 e, with the substitution of a cytosine for a thymine nucleotide (C64T) at codon 22, leading to a prem

209 o one-electron oxidized thymidine (dThd) and thymine nucleotides in basic aqueous glasses is investig

210 ectly with either the 5mC N4 nitrogen or the thymine O4 oxygen.

211 lesion, the most common oxidation product of thymine, occurs via two alternative pathways, in one of

212 of O(6)-Bn-dG to intercalate between Per and thymine of the 3'-neighbor A:T base pair.

213 ng the duplex length and mutating the fourth thymine of the continuous sequence of thymines to cytosi

214 The electrooxidation of thymine on screen-printed carbon electrodes was investig

215 e (TDG) excises the mismatched base, uracil, thymine or 5-hydroxymethyluracil (5hmU), as well as remo

216 ing a methyl group in the 5-carbon position (thymine or 5-methylcytosine (5mC)).

217 odified phosphoramidites carrying additional thymine or adenine attached to the 2'-position of arabin

218 er an ultraviolet (UV) photon is absorbed at thymine or cytosine.

219 he neutral loss of a base (guanine, adenine, thymine, or cytosine) was added to the original methodol

220 f proton-coupled electron transfer (PCET) in thymine oxidation.

221 rotonated adenine, [N(4444)][Ad].2H(2)O, and thymine, [P(4444)][Thy].2H(2)O, as well as the double sa

222 ough damaged bases, such as abasic sites and thymine photo-dimers.

223 we investigated the role of a homopolymeric thymine [poly(T)] tract -50 to -33 relative to the sabA

224 ce is slightly greater for binding at the 5' thymine position than at the 3' thymine position, presum

225 ng at the 5' thymine position than at the 3' thymine position, presumably because of stabilization ar

226 ynamically favored over dGTP binding at both thymine positions of the TTD, most likely due to more pe

227 tyl)-3-O-nosyl-2-deoxy-beta-D-lyxofuranosyl] thymine precursor on the EWOD chip starting from the fir

228 ation in urine and bile of rats treated with thymine propenal (Tp).

229 revealed three metabolites (6% of Tp dose): thymine propenoate and two mercapturate derivatives of g

230 a conserved cysteine donates a H atom to the thymine radical, resulting in a putative thiyl radical.

231 suitable biomarker for prokaryotic cells and thymine Raman band for eukaryotic cells.

232 ther base reduced the blockage, cytosine and thymine reduced the blockage more significantly than ade

233 thymidine depletion, and supplying exogenous thymine rescues both nucleotide levels and cell prolifer

234 ethylated cytosine occupies one of the inner thymine residues corresponding to the AP-1 element, resu

235 Therefore, the SP structure where the two thymine residues maintain a stacked conformation likely

236 uctive cleavage reaction to revert SP to two thymine residues.

237 tigation of DNA containing methyl-deuterated thymine reveals a large isotope effect establishing that

238 Permanganate reactivity of thymines reveals that strand backbones in open regions o

239 er the activity of Exo III toward a designed thymine-rich DNA oligonucleotide (e-T-rich probe) by the

240 We identify adenine-thymine-rich interactive domain-3a (Arid3a), a factor es

241 ode putative transmembrane domains, and that thymine-rich intergenic regions harbor a widespread pote

242 ansmembrane polypeptides emerge de novo from thymine-rich non-genic regions and subsequently accumula

243 th ssDNA based linker in the middle and poly thymine sequences on both 3' and 5' ends as a template f

244 olic monomeric G-tetrad in comparison to the thymine species.

245 lity of GM-strains of Bacteroides to survive thymine starvation and overcome it through the exchange

246 e and origin-proximal DNA degradation during thymine starvation have now been quantified via whole-ge

247 Thymine starvation is exceptional, because it kills cell

248 Here, we show that thymine starvation leads to accumulation of both single-

249 A single guanine-to-thymine substitution mutant required much higher ion con

250 mage include a high frequency of cytosine to thymine substitutions (C-to-T) at the ends of fragments,

251 Thymine substitutions for adenine at position -7 in the

252 We have examined the effect of three thymine (T) analogs including uracil (U), 5-fluorouracil

253 A hairpins with fewer that seven adenine (A):thymine (T) base pairs.

254 quence d(TG4T) contains only guanine (G) and thymine (T) bases and has medical and nanotechnological

255 sequence leads to reformation of the intact thymine (T) bases.

256 iro-oxetanoribonucleosides of uracil (U) and thymine (T) in 37 and 45% overall yields, respectively.

257 s, for example guanine (G), adenine (A), and thymine (T) in a beef and chicken livers samples to meas

258 he length (6, 10, or 14 bases) and identity (thymine (T) or adenine (A)) of the spacer connecting the

259 helix with the base pairs of adenine (A) and thymine (T) or cytosine (C) and guanine (G), but G-rich

260 Strikingly, cytocine (C) to thymine (T) transitions are found to be overrepresented

261 Adenine (A) and thymine (T) were deposited as electron-blocking/hole-tra

262 (Adenine (A), Guanine (G), Cytosine (C), and Thymine (T)) on single-stranded DNA (ssDNA) and double-s

263 Guanine (G), adenine (A), thymine (T), and cytosine (C) are the four basic constit

264 genetic bases of adenine (A), cytosine (C), thymine (T), and guanine (G).

265 s of adenine (A), guanine (G), cytosine (C), thymine (T), and uracil (U) are investigated.

266 This study presents a thymine (T)-based molecular beacon (MB) used for probing

267 vely, the initial chromosomal replication in thymine (T)-starved cells could reflect a considerable e

268 ng, we introduced multiple Hg binding units (thymine (T)-T pairs) in a molecular trawl made of two po

269 r is developed by integrating thymine-Hg(2+)-thymine (T-Hg(2+)-T) base pairs for the high selectivity

270 By utilizing thymine-Hg(2+)-thymine (T-Hg(2+)-T) coordination chemistry, label-free

271 ough the formation of the complex Thymine-Hg-Thymine (T-Hg-T): in fact, Hg(2+) tends to bind two thym

272 report for Cu nanocluster nucleation on ploy thymine tails of ssDNA which performed in two reduction

273 an initial report of a stabilized individual thymine tetrad assembly is presented here.

274 icient at mutating 5-methylcytosine (5mC) to thymine than APOBEC3A in a genetic assay and was at leas

275 These enzymes must minimize excision of thymine that is not generated by mC deamination, in A.T

276 For the nucleobase thymine, the oxygen Auger spectrum shifts towards high k

277 seq), unmodified C, 5fC and 5caC are read as thymine; thus 5fC and 5caC cannot be distinguished from

278 xperimental and computational approach, that thymine (Thy) molecules diffuse through the pores of the

279 ost relevant BP/DNA interactions occurs with thymine (Thy).

280 t known for its ability to bypass UV-induced thymine-thymine (T-T) dimers and other bulky DNA lesions

281 out of GMR biosensor and high selectivity of thymine-thymine (T-T) pair for Hg(2+).

282 le against skin cancer caused by cyclobutane thymine-thymine dimers (TTDs), a frequent form of DNA da

283 Lastly, vLEE induced the conversion of thymine to 5,6-dihydrothymine (5,6-dhT) within TpT, a re

284 Oxidation of a DNA thymine to 5-hydroxymethyluracil is one of several recen

285 hen sequenced with SLAMseq, which introduces thymine to cytosine (T>C) conversions at the sites of th

286 fourth thymine of the continuous sequence of thymines to cytosine or guanine significantly, and somet

287 titutions occurring at cytosines preceded by thymines (Tp*C sites) than adenocarcinomas.

288 ypermutated profile enriched for cytosine-to-thymine transitions.

289 ) during replication resulting in guanine to thymine transversion mutations.

290 adenine moieties of Poly A nanocapsules and thymine/uracil does not affect the fluorescence of poly

291 n both nucleic acids, is highly specific for thymine/uracil, and maintains and slightly stabilises th

292 In comparisons of base-pair steps with thymine versus uracil, the thymine methyl group tends to

293 -vinyl carbazole nucleoside with an opposite thymine when irradiated at 365 nm.

294 seq, both cytosines and 5mCs are read out as thymines, whereas only 4mCs are read out as cytosines, r

295 es unmethylated cytosines to be sequenced as thymine, which allows methylation levels to reflected in

296 higher than that one of the coupling Adenine-Thymine, which can be employed for a selective, fast and

297 first guanine and the next two guanines by a thymine, which forms a single-residue bulge and is proje

298 with a 10-nucleotide ssDNA composed of poly-thymine, which reveals a novel positively charged nuclei

299 duplex and contains a continuous sequence of thymines, which is the pause signal for RNA polymerase I

300 t, we noted the hydantoin ring of dGh mimics thymine, while the iminohydantoin ring of dIa mimics cyt