ライフサイエンスコーパス: tissue remodeling

1 to changes in diet and maintains homeostatic tissue remodeling.

2 keletal muscle is a highly dynamic period of tissue remodeling.

3 velopment of chronic airway inflammation and tissue remodeling.

4 injury, and signaling through uPAR promotes tissue remodeling.

5 -distance communication during postembryonic tissue remodeling.

6 filtration, epithelial cell hyperplasia, and tissue remodeling.

7 involved in normal and pathologic intestinal tissue remodeling.

8 tiation program that regulates granulomatous tissue remodeling.

9 ate mammary gland (MG) development and adult tissue remodeling.

10 ducible secreted glycoproteins that underlie tissue remodeling.

11 e phagocytosis, anti-microbial activity, and tissue remodeling.

12 be a relevant target to regulate connective tissue remodeling.

13 rapid regulation is essential for organized tissue remodeling.

14 sulfate have been suggested to induce kidney tissue remodeling.

15 ng lipid metabolism, energy homeostasis, and tissue remodeling.

16 in homeostasis are altered upon pathological tissue remodeling.

17 haracterized by bronchiolar inflammation and tissue remodeling.

18 hat drive epithelial cell rearrangements and tissue remodeling.

19 regulatory functions in innate immunity and tissue remodeling.

20 search in the field of PCD and developmental tissue remodeling.

21 acellular matrix and plays an active role in tissue remodeling.

22 a surprising association with fibrinogen and tissue remodeling.

23 n of PAX6 after birth may lead to corrective tissue remodeling.

24 vents that are collectively known as adipose tissue remodeling.

25 e dynamics of ATM that contribute to adipose tissue remodeling.

26 are used for cell motility, cytokinesis, and tissue remodeling.

27 llular matrix (ECM) which causes destructive tissue remodeling.

28 anscripts correlated with several indexes of tissue remodeling.

29 airway hyper-responsiveness and contractile tissue remodeling.

30 cellular cues and affect ECM composition and tissue remodeling.

31 ch lead to impaired lung injury recovery and tissue remodeling.

32 growth factor-beta1) to promote maladaptive tissue remodeling.

33 expression in adult tissue is indicative of tissue remodeling.

34 matrix production and progressive connective tissue remodeling.

35 sustain, and propagate immune responses and tissue remodeling.

36 velopment of chronic airway inflammation and tissue remodeling.

37 e extracellular matrix for wound healing and tissue remodeling.

38 tion after wounding and displayed defects in tissue remodeling.

39 might best aid in osseointegration and soft tissue remodeling.

40 ate in cellular homeostasis, adaptation, and tissue remodeling.

41 ortion of M2-type macrophages, which promote tissue remodeling.

42 n lipotoxicity-related lung inflammation and tissue remodeling.

43 s) are critical for hepatic wound repair and tissue remodeling.

44 s characterized by increased cellularity and tissue remodeling.

45 ted deaths, increased luminal diameters, and tissue remodeling.

46 ltiple physiologic processes associated with tissue remodeling.

47 th especially important roles in disease and tissue remodeling.

48 known about how physiological factors elicit tissue remodeling.

49 ed in cell cycle, DNA damage, apoptosis, and tissue remodeling.

50 te survival signals for hepatocytes in adult tissue remodeling.

51 iating both local inflammation and excessive tissue remodeling.

52 processes, such as cell differentiation and tissue remodeling.

53 er transcriptional repressor, Snail1, during tissue remodeling.

54 ping organs, whereas others are more akin to tissue remodeling.

55 of collagen expression and deposition during tissue remodeling.

56 ermittent hypoxia on airway inflammation and tissue remodeling.

57 sion and allowing for full quantification of tissue remodeling.

58 are important mediators of inflammation and tissue remodeling.

59 well-supported assumptions of developmental tissue remodeling.

60 actin filaments, probably linked with tumor tissue remodeling.

61 lammation via recruitment of neutrophils and tissue remodeling.

62 n myofibroblast differentiation and fibrotic tissue remodeling.

63 th actin suggests a new role of SPARC during tissue remodeling.

64 ration of tissue injury and induces abnormal tissue remodeling.

65 this pleiotropic adipokine in regulation of tissue remodeling.

66 e extracellular matrix deposition and muscle tissue remodeling.

67 genesis, immune-interaction and invasion and tissue-remodeling.

68 mineralized fibrocartilage, with very little tissue remodeling 5 weeks after cell ablation.

69 ole for macrophage MMP-10 in controlling the tissue remodeling activity of macrophages and moderating

70 essential for lymphoid tissue formation and tissue remodeling after damage.

71 ways characterized by T(H)2 inflammation and tissue remodeling after exposure to inhaled allergens.

72 -linking of proteins is an essential step in tissue remodeling after injury.

73 yte infiltration, inflammation, and fibrotic tissue remodeling after renal IRI, thus preventing progr

74 tracellular matrix (ECM) that contributes to tissue remodeling after revascularization interventions.

75 n the sinonasal epithelial cell barrier, and tissue remodeling all contribute to the chronic inflamma

76 Metalloproteinases (MMPs) contribute to tissue remodeling and acute inflammation not only by deg

77 Type 2 lymphocytes promote both physiologic tissue remodeling and allergic pathology, yet their phys

78 and an upregulation of molecules involved in tissue remodeling and angiogenesis.

79 ived elastinolytic protease in inflammation, tissue remodeling and angiogenesis.

80 se most cardiomyopathies are associated with tissue remodeling and architecture alterations.

81 g to reduction of TH2-mediated inflammation, tissue remodeling and bronchial hyperresponsiveness.

82 phages are involved in tumor progression and tissue remodeling and can be profibrotic in certain cond

83 insights regarding ADSC influence on breast tissue remodeling and determine patient-dependent factor

84 sed expression of multiple genes involved in tissue remodeling and extracellular matrix homeostasis.

85 s a critical TGF-beta effector in underlying tissue remodeling and fibrosis throughout the body, alth

86 They are the primary "effector" cells in tissue remodeling and fibrosis.

87 lar CRT signaling plays an important role in tissue remodeling and fibrosis.

88 s a regulatory gene that promotes epithelial tissue remodeling and formation of branched organs.

89 eading to impaired cardiac function, adverse tissue remodeling and heart failure.

90 and restoration of neuronal function during tissue remodeling and highlight the need for mechanistic

91 mmune responses that drive mucus production, tissue remodeling and immune cell infiltration.

92 , and cell proliferation, and plays roles in tissue remodeling and immune regulation.

93 -13 Tg mice developed considerable pulmonary tissue remodeling and inflammation.

94 Complications are due to tissue remodeling and involve TGF-beta1-mediated fibrosi

95 characterized by persistent inflammation and tissue remodeling and is a leading cause of death in the

96 ong association between proteins involved in tissue remodeling and leukocyte infiltration with the lu

97 giogenic protein that has been implicated in tissue remodeling and local vascular inflammation.

98 and endocrine factors to orchestrate adipose tissue remodeling and maintain systemic homeostasis.

99 e pathological consequence of stress-induced tissue remodeling and matrix accumulation.

100 further resulted in an earlier transition to tissue remodeling and maturation with a shift in collage

101 more, lack of c-Met had a profound effect on tissue remodeling and overall composition of HSC niche,

102 bmucosa of NP, which might contribute to the tissue remodeling and pathogenesis of CRS with nasal pol

103 bmucosa of NP, which might contribute to the tissue remodeling and pathogenesis of CRS with NP.

104 system disease and injury, including active tissue remodeling and phagocytosis.

105 Myofibroblasts accumulate at sites of tissue remodeling and produce extracellular matrix compo

106 ne has an important role in inflammation and tissue remodeling and promotes dermal fibrosis by adenos

107 nic development, immune system function, and tissue remodeling and regeneration.

108 aptation during tissue repair sets PTX3 in a tissue remodeling and repair mode, suggesting that matri

109 timicrobial host defense, but also modulates tissue remodeling and repair responses to endogenous lig

110 and inflammation that may eventually lead to tissue remodeling and respiratory disease.Cystic fibrosi

111 stemic antiviral immune responses to adipose-tissue remodeling and reveal an underappreciated role of

112 nflammatory response resulting in submucosal tissue remodeling and scarring.

113 n distributions during Drosophila epithelial tissue remodeling and show that Rab35 is dynamically pla

114 ifts in organismal physiology to orchestrate tissue remodeling and some cancers are understood to ari

115 altered intestinal gene expression promoting tissue remodeling and suppression of apoptosis-the effec

116 , the TRAIL pathway plays a critical role in tissue remodeling and targeting upregulated DR5 in alpha

117 pected roles of Hpse2 in bladder physiology, tissue remodeling and Tgfbeta signaling.

118 rowing body of work on their role in adipose tissue remodeling and thermogenesis.

119 ate the critical role of adult stem cells in tissue remodeling and unravel the complexity of stem cel

120 eratinocytes, angiogenesis, and, ultimately, tissue remodeling and wound closure.

121 revealed that multiple genes associated with tissue remodeling and wound healing were up-regulated by

122 a) is induced on tissue injury and regulates tissue remodeling and wound healing, but dysregulated si

123 r-promoting reparatory, trophic, angiogenic, tissue remodeling, and anti-inflammatory pathways.

124 ll differentiation as well as tissue growth, tissue remodeling, and apoptosis.

125 ation, innate and adaptive immune responses, tissue remodeling, and arachidonic acid metabolism.

126 ls of TGF-beta and proteases associated with tissue remodeling, and diminished Smad2 signaling.

127 delivery of NGF enables neural regeneration, tissue remodeling, and functional recovery in mice with

128 e been shown to be involved in host defense, tissue remodeling, and immunity regulation.

129 tical roles in promoting tumor angiogenesis, tissue remodeling, and immunosuppression.

130 T cells, reduced mast cell accumulation and tissue remodeling, and improved lung function but had on

131 ses), modulate cell signaling, inflammation, tissue remodeling, and leukocyte recruitment via cleavag

132 ecules involved in proliferation, signaling, tissue remodeling, and macrophage recruitment.

133 is associated with adipocyte death, adipose tissue remodeling, and metabolic dysfunction.

134 sponse, coagulation and complement cascades, tissue remodeling, and metabolic homeostasis that were a

135 osis and subsequent inflammation resolution, tissue remodeling, and organ function.

136 eviously implicated in chronic inflammation, tissue remodeling, and PH.

137 resolution of atherosclerotic inflammation, tissue remodeling, and plaque contraction during atheros

138 ogression through induction of angiogenesis, tissue remodeling, and suppression of the cytotoxic T ly

139 The influence of B cells on lung function, tissue remodeling, and the immune response were analyzed

140 ecause of their rapid cellular repopulation, tissue remodeling, and therewith self-repair capacity.

141 on of genes involved in asthma pathogenesis, tissue remodeling, and tight junction formation.

142 and scaffold molecules during inflammation, tissue remodeling, and wound healing.

143 opment to fill context-specific functions in tissue remodeling, angiogenesis, and immunity.

144 ILCs function in lymphoid organogenesis, tissue remodeling, antimicrobial immunity, and inflammat

145 ase L in CS plus virus induced inflammation, tissue remodeling, apoptosis, and cytokine elaboration a

146 Lung fibrosis and tissue remodeling are features of chronic diseases such

147 and microvascular dysfunction, fibrosis, and tissue remodeling are needed and ideally would be obtain

148 New bone formation and tissue remodeling are the major challenges in implantolo

149 involved in fibrinolysis, wound healing, and tissue remodeling, as a novel serum-derived factor promo

150 associated with reduced stiffness and higher tissue remodeling, as well as a dual mechanical behavior

151 pression of genes that regulate fibrosis and tissue remodeling, as well as expression of collagen typ

152 the long-term pathophysiological changes and tissue remodeling associated with chronic allergic infla

153 in the metabolic alterations and the adipose tissue remodeling associated with obesity.

154 proteinases have been largely implicated in tissue remodeling associated with pathological processes

155 omposition and differential expression of 45 tissue remodeling-associated genes in transbronchial lun

156 une cells have beneficial roles in postnatal tissue remodeling, but roles for the adaptive immune sys

157 mulation by up to 42%, concomitantly reduced tissue remodeling by 50%, and decreased inflammatory cel

158 ve extracellular matrix (ECM) deposition and tissue remodeling by activated myofibroblasts, leads to

159 Uterine tissue remodeling by alpha-chymase (mast cell protease [

160 omote favorable conditions for normal breast tissue remodeling by changing the microenvironment.

161 is, and asbestosis, trigger inflammation and tissue remodeling by inducing IL-1beta secretion, leadin

162 or calpains in mediating HFD-induced adipose tissue remodeling by influencing multiple functions incl

163 iated brain cells in regenerative growth and tissue remodeling by influencing the abundance of brain

164 , the regulation of autoimmune inflammation, tissue remodeling, cancer and metabolic homeostasis.

165 for TED that target or prevent the excessive tissue remodeling caused by myofibroblast formation and

166 This study provides insight into the adipose tissue-remodeling changes that induce regulation of adip

167 Obesity is associated with adipose tissue remodeling, characterized by adipocyte hypertroph

168 known, multilayered regulation of epithelial tissue remodeling coordinated by the microRNA cluster mi

169 architecture, extracellular matrix-mediated tissue remodeling, cytoskeletal organization, epithelial

170 The term "transitional tissue remodeling" describes qualitative and quantitativ

171 very dynamic organ that undergoes continuous tissue remodeling during adulthood.

172 ngs reveal unexpected roles for apoptosis in tissue remodeling during development, as well as in rege

173 Collective cell migration drives tissue remodeling during development, wound repair, and

174 n and associated vasculature changes lead to tissue remodeling during each reproductive cycle.

175 apical junctions and are required for proper tissue remodeling during early stages of neurodevelopmen

176 tructural alterations indicative of areas of tissue remodeling during gestation.

177 olleagues demonstrate that postpartum breast tissue remodeling during involution coincides with infla

178 wide range of biological processes including tissue remodeling during organogenesis, organ homeostasi

179 ritical role in solute transport defects and tissue remodeling during PD-related peritonitis.

180 ived from the heart tube contribute to local tissue remodeling during valve development.

181 These findings reveal that regulation of tissue remodeling during vertebrate development can be d

182 ntiation 90 OR (CD90)+ nonmyocytes optimized tissue remodeling dynamics and yielded enhanced structur

183 astic, releasing proinflammatory factors and tissue-remodeling enzymes.

184 (TG2), a multifunctional protein involved in tissue remodeling events related to organ fibrosis and c

185 hibitor (PAI-1), controls blood clotting and tissue remodeling events that involve cell migration.

186 gh a diverse array of signaling pathways and tissue remodeling events.

187 sease features; this was especially true for tissue remodeling events.

188 ration of epithelial cells underlies diverse tissue-remodeling events, but the mechanisms that coordi

189 ent in innate and acquired immune responses, tissue remodeling, fibrosis, and serving as virulence fa

190 ion, endothelial cell activation/injury, and tissue remodeling/fibrosis, with macrophage/dendritic ce

191 lume fraction and tauic can track myocardial tissue remodeling from pressure overload.

192 nt-FoxO-Hippo pathway (from E10.5 to E11.5), tissue remodeling (from E12.5 to E13.5) and miR-129-5p-m

193 ivation status, suggestive of angiogenic and tissue remodeling functions.

194 gest distinct functions for these subsets in tissue remodeling, growth, and development.

195 The interest in adipose tissue remodeling has been accelerated by the current ep

196 h mechanical regulation of cell function and tissue remodeling has long been appreciated in other con

197 ighly regulated control of the extracellular tissue remodeling; however the mechanism of this regulat

198 e myofibroblast and mechanisms of connective tissue remodeling; ii) factors controlling the expressio

199 a process that represents a critical step in tissue remodeling, immune responses, and the resolution

200 riction is a cell shape change that promotes tissue remodeling in a variety of homeostatic and develo

201 relationship between WSS and regional aortic tissue remodeling in BAV patients to determine the influ

202 f extracellular matrix proteases involved in tissue remodeling in both physiologic and pathophysiolog

203 and their growth factor ligands orchestrate tissue remodeling in chronic transplant dysfunction.

204 eostasis model assessment index, and adipose tissue remodeling in HFD rats.

205 sms whereby IL-17A mediated inflammation and tissue remodeling in human tenocytes.

206 mprehensive and unbiased characterization of tissue remodeling in many biomedical contexts.

207 lt from chronic inflammation that interrupts tissue remodeling in normal wound healing.

208 inflammation, and favorably modulate adipose tissue remodeling in obesity.

209 ion of transcripts associated with promoting tissue remodeling in Pirb(-/-) eosinophils, including pr

210 of the pro-inflammatory OPN cytokine during tissue remodeling in response to challenge in G allele c

211 cells and small-intestine cells that mediate tissue remodeling in response to colonizing helminths an

212 group of extracellular proteases involved in tissue remodeling in several physiological and pathophys

213 ported to promote functional skeletal muscle tissue remodeling in small and large animal models of VM

214 d cells to the promotion of tissue repair or tissue remodeling in the affected site.

215 ndocardium is indispensable for the valvular tissue remodeling in the heart.

216 Puberty is characterized by dynamic tissue remodeling in the mammary gland involving ductal

217 at GAS2 is a critical and novel regulator of tissue remodeling in the ovary during oocyte cyst breakd

218 ted in activated fibroblasts associated with tissue remodeling in various common diseases such as can

219 exposure of obese mice triggers an adaptive tissue remodeling in visceral adipose tissue (VAT) that

220 reduced Tregs at this stage interfered with tissue remodeling, in contrast to Treg transient ablatio

221 A clinical hallmark is extensive tissue remodeling including basal zone hyperplasia, fibr

222 KLF15 of pathways implicated in pathological tissue remodeling, including distinct Wnt-pathways that

223 Genes associated with fibrosis and tissue remodeling, including matrix metalloproteases and

224 8 in promoting chronic lung inflammation and tissue remodeling induced by cigarette smoke and highlig

225 found, which included biomarkers of fibrosis/tissue remodeling, inflammation, renal injury/dysfunctio

226 regulation of groups of genes important for tissue remodeling, innate immunity, and mitogen-activate

227 Tissue remodeling is a characteristic of many solid tumo

228 This tissue remodeling is associated with chronic gastroesoph

229 Our data suggest that tissue remodeling is not a feature of PAR and argues tha

230 cellular protein that participates in normal tissue remodeling, is associated with a variety of disea

231 Interestingly, a key factor in tissue remodeling, Kruppel-like factor 6 (KLF6) transloc

232 ation are determined since these may promote tissue remodeling linked with thyroid-associated ophthal

233 hat, in at least these examples of cutaneous tissue remodeling, mast cells may not have nonredundant

234 During tissue remodeling, matricellular proteins (MCP) are secr

235 activity in clonogenic growth, architectural tissue remodeling, migration, invasion, and lung coloniz

236 wth hormone binding protein), and connective tissue remodeling (MMP3).

237 luding many epithelium-like injury molecules tissue, remodeling molecules, and inflammation molecules

238 osis or decreasing brain cell number through tissue remodeling (morphallaxis), as appropriate.

239 tive disease that manifests with detrimental tissue remodeling, myofibroblast accumulation, and scarr

240 rized macrophages encompass biomaterials and tissue remodeling needs, yet harnessing or directing the

241 the unknown controls of autonomous, rhythmic tissue remodeling of the HF, which intersects developmen

242 n condition associated with inflammation and tissue remodeling of the nose and paranasal sinuses, fre

243 vivo activity can lead to extremely diverse tissue-remodeling outcomes.

244 ncreased cellular metabolism with associated tissue remodeling pathways were present in patients with

245 26), barrier molecules (desmoglein 1, DSG1), tissue remodeling (periostin, POSTN), and mast cells (ca

246 especially with 5% w/v HA recapitulated the tissue remodeling process of human bone via coupling sig

247 We propose to abate this tissue remodeling process through immunotherapy administ

248 e plasminogen activator (uPA), is central in tissue remodeling processes and also strongly implicated

249 Tissue remodeling processes critically depend on the tim

250 Mediators released from MCs may regulate tissue remodeling processes, thereby contributing to IPF

251 licated in tissue injury and elevated during tissue remodeling processes.

252 kes this a promising technology for studying tissue remodeling processes.

253 ention as critical mediators of pathological tissue remodeling processes.

254 an important role in normal and pathological tissue remodeling processes.

255 functions in the context of morphogenetic or tissue remodeling processes.

256 affecting many cell types and implicated in tissue remodeling processes.

257 ted cross-linked provisional matrix in adult tissue remodeling remains to be defined.

258 tory in nature and are generally involved in tissue remodeling, repair, and homeostasis.

259 rticipate in local immune regulation and the tissue remodeling/repair events linked with a variety of

260 uces exaggerated inflammatory, cytokine, and tissue remodeling responses.

261 notypic and dietary effects on white adipose tissue remodeling resulted in profound increases in fatt

262 Poststroke tissue remodeling results in a compartmentalized cavity

263 and glia play fundamental roles in post-SCI tissue remodeling.SIGNIFICANCE STATEMENT Spinal cord inj

264 Finally, AFC had effects on adipose tissue remodeling similar to those of rosiglitazone and

265 5, TSLP, and CCL26 and genes associated with tissue remodeling, such as COL8A1, actin gamma-2 (ACTG2)

266 lammation and allowing natural uninterrupted tissue remodeling suggests new therapeutic opportunities

267 contributes to both acute kidney injury and tissue remodeling that is associated with chronic kidney

268 oxphos), thereby contributing to maladaptive tissue remodeling that is associated with, and possibly

269 ic TH2 inflammatory disease characterized by tissue remodeling that leads to esophageal strictures an

270 echanistic link between oxidative stress and tissue remodeling that may find applicability in the cli

271 essive collagen accumulation and destructive tissue remodeling that occurs in fibrotic diseases such

272 into adjacent normal tissues where it causes tissue remodeling that permits local invasion.

273 forcing actions was predictive of a positive tissue remodeling that was essential for the long-standi

274 ogenesis is perceived to involve substantial tissue remodeling, the roles of MT-MMPs in these process

275 ize the macrophage phenotype responsible for tissue remodeling: the hitherto elusive restorative macr

276 lfate and p-cresol sulfate may induce kidney tissue remodeling through direct binding and activation

277 mediator of tumorigenesis, inflammation and tissue remodeling through its ability to degrade critica

278 trate that PGCs take advantage of endodermal tissue remodeling to gain access to the gonadal mesoderm

279 iferation during regeneration and for proper tissue remodeling to occur to maintain scale and proport

280 nositol (GPI)-anchored protein that promotes tissue remodeling, tumor cell adhesion, migration and in

281 roteinase-9 (MMP-9) plays a critical role in tissue remodeling under both physiological and pathologi

282 ify the molecular mechanisms underlying this tissue remodeling using cultured human proximal renal tu

283 ion patterns suggests C. innocuum stimulates tissue remodeling via M2 macrophages, leading to an adip

284 play important roles in innate immunity and tissue remodeling via production of various cytokines an

285 pression of some trophic factors involved in tissue remodeling was congruent with the cellular events

286 ity of ECMs to orchestrate functional muscle tissue remodeling was interrogated in a porcine VML inju

287 Finally, regarding tissue remodeling, we observed elastosis of the lung par

288 that encode for proteins that play a role in tissue remodeling were also expressed.

289 velopment of HFD-induced obesity and adipose tissue remodeling, whereas it significantly increased he

290 uring exercise, paracrine factors coordinate tissue remodeling, which underlies this healthy adaptati

291 es show evidence of ongoing inflammation and tissue remodeling, which were more marked where clinical

292 of the involvement of macrophages in adipose tissue remodeling will promote one aspect of the new fie

293 review the current understanding of adipose tissue remodeling with a focus on obesity-induced adipos

294 elated to BPH stromal hyperproliferation and tissue remodeling with a local hypoxia induced by increa

295 y triggering local inflammation and inducing tissue remodeling with consequences for peritoneal membr

296 hagus defined by eosinophil infiltration and tissue remodeling with resulting symptoms of esophageal

297 Progressive disease leads to pathologic tissue remodeling, with ensuing esophageal rigidity and

298 MMPs function in tissue remodeling within the extracellular space and are

299 illar collagen underlies processes including tissue remodeling, wound healing, and cancer metastasis.

300 that mechanical stress plays a major role in tissue remodeling, yet its role in diverticulosis has no