ライフサイエンスコーパス: tissue repair

1 o developing applications for human tracheal tissue repair.

2 icity that is essential for host defense and tissue repair.

3 s of mesenchymal cells, resulting in minimal tissue repair.

4 sition of a type 2 effector program promotes tissue repair.

5 behaviors that facilitate wound closure and tissue repair.

6 re also being viewed as important players in tissue repair.

7 ury as cells aberrantly differentiate during tissue repair.

8 e repair mechanisms hold great potential for tissue repair.

9 to promote the complex and active process of tissue repair.

10 ites of tissue injury is critical for normal tissue repair.

11 in that regulates inflammatory responses and tissue repair.

12 ew targets for angiogenic therapy to promote tissue repair.

13 to play important roles in host defence and tissue repair.

14 for arterial revascularization and ischemic tissue repair.

15 ion during acute infectious inflammation and tissue repair.

16 ting that the MDM can be tailored to promote tissue repair.

17 can also benefit self-maintenance and foster tissue repair.

18 rotein required for vascular development and tissue repair.

19 lfation as a therapeutic target for ischemic tissue repair.

20 preferentially induced factors implicated in tissue repair.

21 critical for development, organ growth, and tissue repair.

22 ole in both physiologic and pathophysiologic tissue repair.

23 arrier to ward off harmful agents and aid in tissue repair.

24 tly unknown, but it might potentially affect tissue repair.

25 ary clearance, innate antiviral defense, and tissue repair.

26 crucial role in wound healing, orchestrating tissue repair.

27 ting in reduced organ function and delays in tissue repair.

28 ishing inflammation and promoting connective tissue repair.

29 tification of a myeloid cell contribution to tissue repair.

30 uding tissue adhesives, wound dressings, and tissue repair.

31 and may be a paradigm for the regulation of tissue repair.

32 cell pool, thus ensuring rapid and efficient tissue repair.

33 ontrol the resolution of inflammation during tissue repair.

34 ISC pool size to the homeostatic level after tissue repair.

35 on, yet not all integrin binding can lead to tissue repair.

36 ctors involved in biological development and tissue repair.

37 functions in cardiovascular development and tissue repair.

38 olarized cell migration and stem cell-driven tissue repair.

39 rsion, directly linking debris engulfment to tissue repair.

40 to quiescence (self-renewal) is crucial for tissue repair.

41 ssential for antimicrobial host defenses and tissue repair.

42 y a beneficial role in injury prevention and tissue repair.

43 ions with stochastic fate acquisition during tissue repair.

44 of parenchymal alveolar tissue and impaired tissue repair.

45 tissues, and control antibody production and tissue repair.

46 restoration of homeostasis and initiation of tissue repair.

47 P) that recapitulates stem cell functions in tissue repair.

48 te and adaptive resistance to infections and tissue repair.

49 ivities that contribute to wound healing and tissue repair.

50 identify an essential function of Nedd4-1 in tissue repair.

51 rgic inflammation, metabolic homeostasis and tissue repair.

52 gnals to maintain other immune cells and aid tissue repair.

53 or intercellular communication to facilitate tissue repair.

54 ing control of infections, inflammation, and tissue repair.

55 ehow underlying molecular events involved in tissue repair.

56 sponse that maintains homeostasis and favors tissue repair.

57 ed retinal cells and immune cells to promote tissue repair.

58 undergoes dramatic remodeling to facilitate tissue repair.

59 sponsiveness to TLR4 stimulation and inhibit tissue repair.

60 ating pathologic inflammation and beneficial tissue repair.

61 diseases, such as neurological disorders and tissue repair.

62 ing adenosine as a potential therapeutic for tissue repair.

63 une cells and stem cells is important during tissue repair.

64 prolonged inflammatory phenotype preventing tissue repair.

65 thogens, host allergic reactions, as well as tissue repair.

66 mmation to deficits in immune regulation and tissue repair.

67 affolds have an exquisite ability to promote tissue repair.

68 lecules that eliminate pathogens and promote tissue repair.

69 nvolved in blood coagulation, hemostasis and tissue repair.

70 olonged intestinal inflammation and impaired tissue repair.

71 lamed intestine of humans, and essential for tissue repair.

72 lular networks emerge during development and tissue repair.

73 ced by IL-4 is important for homeostasis and tissue repair.

74 nd to cellular and tissue injury and promote tissue repair.

75 r and cellular processes required to promote tissue repair.

76 resolution of inflammation and contribute to tissue repair.

77 capable of directly or indirectly promoting tissue repair.

78 ivity of extracellular vesicles that mediate tissue repair.

79 man liver disease, and their contribution to tissue repair.

80 development, host defense, inflammation, and tissue repair.

81 ic tissue injury and play important roles in tissue repair.

82 ydrogel is a promising cell-free therapy for tissue repair.

83 es the transient use of adult precursors for tissue repair.

84 ich damaged cellular material is removed and tissue repaired.

85 emplified by type 2 immunity in induction of tissue repair(2).

86 ppression [2], embryonic development [3, 4], tissue repair [5-8], and organismal aging [9].

87 indicate that lacrimal glands are capable of tissue repair after duct ligation-induced injury, likely

88 Tissue repair after injury is a complex, metabolically d

89 hage (M )-fibroblast interactions coordinate tissue repair after injury whereas miscommunications can

90 e hypothesized that the Sulfs have a role in tissue repair after myocardial infarction.

91 Tissue repair after spinal cord injury requires the mobi

92 d predominant expression of genes related to tissue repair after treatment, making tumor biomarker in

93 f the two trials: comparing standard (native tissue) repair alone with standard repair augmented with

94 ment of protein-based therapies for ischemic tissue repair, also beyond the sole application in heart

95 ntioxidant activity that supports intestinal tissue repair and adenoma development.

96 elicits an inflammatory response that drives tissue repair and adverse cardiac remodeling.

97 an be used to engineer tissue constructs for tissue repair and build biomimetic disease models for st

98 In this Review, we highlight how tissue repair and cancer share cellular and molecular pr

99 standing of the mitogenic effect of IL-17 on tissue repair and cancer.

100 ells for neoangiogenesis during development, tissue repair and cancer.

101 crophages, highly plastic cells that mediate tissue repair and destruction, are prominent within dyst

102 k is rate-limiting in embryonic development, tissue repair and engineering.

103 d biologic activity that affects outcomes in tissue repair and establishes a strategy for modifying E

104 er, whether CD44V6 regulates NOX4 to mediate tissue repair and fibrogenesis is not well-defined.

105 lastic cells that function in wound healing, tissue repair and fibrosis, and arise from bone marrow (

106 ng to disease complications such as aberrant tissue repair and fibrosis.

107 ion after infarction is essential to support tissue repair and function.

108 mental roles for these cells in facilitating tissue repair and guiding vascular re-growth in the cent

109 ution of macrophage-mediated inflammation in tissue repair and have therapeutic implications for the

110 alternative biological approach to improving tissue repair and heart function after MI.

111 ystem and tissue micro-environment to ensure tissue repair and homeostasis.

112 mitogenic pathway in development, as well as tissue repair and homeostasis.

113 uiescent cells to proliferate is critical to tissue repair and homoeostasis.

114 unity, maintenance of tissue homeostasis, or tissue repair and illuminate the distinctions between ti

115 turbations by producing factors that promote tissue repair and improve barrier integrity.

116 bryo formation but also is involved in adult tissue repair and in several malignancies.

117 ogical and pathological processes, including tissue repair and inflammation-related diseases.

118 rentiation of tissue progenitor cells during tissue repair and inflammation.

119 ociated with senescence in normal epithelial tissue repair and its abnormal persistence in disease co

120 nt and exposed a gene set signature to drive tissue repair and lipid metabolism, which was distinct f

121 ance and providing trophic support to ensure tissue repair and maintain cerebral homeostasis.

122 e production of factors normally involved in tissue repair and maintenance.

123 esponses have emerged as major regulators of tissue repair and metabolic homeostasis even under stead

124 ult in severe compromise of multiple organs, tissue repair and organ function recovery can be expecte

125 it functions to maintain tissue homeostasis, tissue repair and organismal health.

126 innate ability to enhance endogenous neural tissue repair and promote functional recovery.

127 BMSCs can resume their role in regenerative tissue repair and promote healing of diabetic wounds.

128 understand the role of scarring in limiting tissue repair and recovery.

129 It is a negative regulator of tissue repair and regeneration in multiple organs.

130 on self-maintenance for their functions, and tissue repair and regeneration in renal diseases.

131 revealed that dietary cholesterol induced a tissue repair and regeneration phenotype in Kupffer cell

132 Inflammation also stimulates tissue repair and regeneration to restore homeostasis an

133 As central drivers of tissue repair and regeneration, it is necessary to under

134 Inflammation plays an important role in tissue repair and regeneration.

135 circulating progenitor cells are involved in tissue repair and regeneration.

136 an emerging signaling mechanism involved in tissue repair and regeneration.

137 M2 macrophages play an important role in tissue repair and regeneration.

138 mbryonic development, cancer metastasis, and tissue repair and regeneration.

139 Thus, immune modulation is required during tissue repair and regeneration.

140 osynthetic pathway and provide mechanisms in tissue repair and regeneration.

141 ation can help develop strategies to promote tissue repair and regeneration.

142 in SLE and revealed pathways associated with tissue repair and remodeling.

143 ptotic cells that can accumulate and inhibit tissue repair and remyelination.

144 omising clinical route that would aid faster tissue repair and reperfusion in "no-option" patients su

145 scaffolds offers a promising alternative for tissue repair and replacement.

146 sures robust termination of inflammation for tissue repair and restoration of normal tissue homeostas

147 to control organ-like tumor features such as tissue repair and revascularization and treat intratumor

148 elasticity are also highly expected for soft tissue repair and soft electronics.

149 al stability may find broad applications for tissue repair and soft/stretchable/wearable bioelectroni

150 Although dedifferentiation is central to tissue repair and stemness, this process inherently carr

151 Recent studies suggest the role of Fhl2 in tissue repair and the anti-inflammatory response.

152 ly inflammation that is essential for normal tissue repair and the pathologic inflammation that can o

153 cules that spread within tissues to organize tissue repair and the specification of cell fate during

154 the mechanisms of CD34Exo-mediated ischemic tissue repair and therapeutic angiogenesis by studying t

155 for endosomal PAR2 signaling in pathways of tissue repair and tumor biology.

156 directly act on tissue stem cells to promote tissue repair and tumorigenesis.

157 ome) frequently arises during organogenesis, tissue repair, and age-associated diseases.

158 lay critical roles in immunity, development, tissue repair, and cancer, but studies of their function

159 f their ability to modulate immunity, foster tissue repair, and differentiate into mesodermal cells.

160 Morphological changes during development, tissue repair, and disease largely rely on coordinated c

161 r with multiple roles in neural development, tissue repair, and disease.

162 metabolism, oxidative stress, inflammation, tissue repair, and growth factor response, as well as re

163 S phase entry is essential for development, tissue repair, and immune defences.

164 e immune cells, enhanced neuroprotection and tissue repair, and improved the success of photoreceptor

165 its importance in nephrogenesis, successful tissue repair, and in opposing malignant transformation.

166 defense against influenza infection, reduces tissue repair, and inflicts caspase-dependent disease pa

167 lay a central role in embryonic development, tissue repair, and metastatic disease.

168 during acute lung injury, enhance pulmonary tissue repair, and promote survival in ADA(-/-) mice.

169 ion of Matrilin-2 limit OPC differentiation, tissue repair, and recovery in this disease.

170 ation of stem cells, responsible for injured tissue repair, and simultaneously discourage bacterial c

171 hematopoiesis, organogenesis, inflammation, tissue repair, and thermogenesis.

172 iferation is necessary for immune responses, tissue repair, and upkeep of organ function to maintain

173 es the chances for success of MSC therapy in tissue-repair applications.

174 es associated with dampened inflammation and tissue repair are elicited in the UGT of Chlamydia-infec

175 h epithelial barriers, dormant programmes of tissue repair are immediately activated.

176 ng the interactions between inflammation and tissue repair at mucosal surfaces in early life remain u

177 The enzyme is implicated in tissue repair but also antagonizes the production of NO

178 lls (ILCs) are critical for host defense and tissue repair but can also contribute to chronic inflamm

179 s host-protective antimicrobial immunity and tissue repair but can also enhance disease severity in s

180 ental processes in embryonic development and tissue repair but confer malignant properties to carcino

181 s less clear: Hox genes are expressed during tissue repair, but in this context their function(s) are

182 hages clears up cellular debris and promotes tissue repair, but it also inflicts secondary injury fro

183 ed with clearance of helminth infections and tissue repair, but the phenotype depends on the cellular

184 les (MSC-EVs) have shown great potential for tissue repair, but their therapeutic capacity is limited

185 viously unappreciated pathway for endogenous tissue repair by a highly regenerative neuroepithelium a

186 Injection of HMGB1 accelerates tissue repair by acting on resident muscle stem cells, h

187 rophages, how resolution of inflammation and tissue repair by macrophages could be promoted by type 2

188 mice, IL-33R (ST2)-expressing Tregs mediate tissue repair by producing the growth factor amphireguli

189 lator of pathophysiological angiogenesis and tissue repair by targeting a VEGF-HIP1-p38K signaling ax

190 MicroRNA-135a-3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial

191 Tissue repair can thus be modulated up or down by the cu

192 ration and differentiation suggests that the tissue repair capacity of human Tregs may be an innate f

193 In contrast, repeated bouts of tissue repair cause a progressive reduction in MuSC clon

194 entified that changes in myeloid TLR4 during tissue repair correlated with increased expression of th

195 l cells and stromal fibroblasts occur during tissue repair, development, and cancer.

196 ute wounds, oral as a model of "ideal" adult tissue repair due to accelerated closure without scarrin

197 uld synergistically facilitate osteochondral tissue repair during physiological regeneration process.

198 une system plays critical roles in promoting tissue repair during recovery from neurotrauma but is al

199 ft, which is indispensable for normal muscle tissue repair dynamics.

200 vation, inflammation, cellular infiltration, tissue repair enzymes, pathways of oxidative stress, and

201 extracellular matrix remodeling to stimulate tissue repair following CNS injuries.The cystic cavity t

202 al effector cells during type 2 immunity and tissue repair following helminth infections.

203 paired inflammation resolution and defective tissue repair following IAV infection.

204 oles in tissue homeostasis, development, and tissue repair following injury.

205 NRG1) as a key EGF family ligand that drives tissue repair following injury.

206 decreased inflammatory response and improved tissue repair following ischemia-reperfusion injury.

207 n important Wnt-producing regulator of liver tissue repair following localized liver injury.

208 inflammation to perform host protection, and tissue repair functions.

209 s) display immuno-suppressive mechanisms and tissue repairing functions, which are critical to suppor

210 s can also mediate beneficial pro-resolving, tissue-repair functions.

211 s and the induction of anti-inflammatory and tissue repair genes in the lungs after helminth infectio

212 nfection through tolerance mechanisms (e.g., tissue repair) has been virtually ignored (but see [4, 5

213 hanges that influence leukocyte function and tissue repair have not been well characterized.

214 Cells involved in tissue repair, healing, and scarring respond to both ADO

215 tal functions in host inflammatory reaction, tissue repair, homeostasis and immunity.

216 Adaptive angiogenesis is necessary for tissue repair, however, it may also be associated with t

217 tic cell receptors on cardiac macrophages to tissue repair; however, the contribution of precursor mo

218 nses promote parasitic immunity and initiate tissue repair; however, they can also result in immunopa

219 suggest that T reg cells can participate in tissue repair in a manner separable from their immunosup

220 T (iNKT) cells in switching inflammation to tissue repair in an interlukin-4-dependent process.

221 brain or spinal cord is a major obstacle for tissue repair in central nervous system (CNS).

222 MGO to improve PC-mediated angiogenesis and tissue repair in diabetes.

223 hanistic basis for rescuing angiogenesis and tissue repair in diabetic wound treatments.

224 s for controlling inflammation and promoting tissue repair in diabetic wounds.

225 ulate their contribution to inflammation and tissue repair in health and disease.

226 viously unappreciated role for dysfunctional tissue repair in local immunomodulation that may have pa

227 Congruent with the aberrant tissue repair in mice with deficient IL-4 signaling, we

228 the interleukin (IL)-33 receptor ST2 mediate tissue repair in response to IL-33.

229 Our data show evidence of marked levels of tissue repair in the human donor pancreas.

230 que mechanisms by which macrophages instruct tissue repair in the liver, nervous system, heart, lung,

231 f systemic iron homeostasis, is required for tissue repair in the mouse intestine after experimental

232 responses or the balance of inflammation and tissue repair in the resolution of infection.

233 h factors with key roles in gut immunity and tissue repair, including IL-7, Ccl2, Ptgs2, and Amphireg

234 s innate immune cells in the coordination of tissue repair, including previously underappreciated rol

235 f cryopreserved cellular products for use in tissue repair is a relatively new area of medicine in wh

236 Tissue repair is a subset of a broad repertoire of inter

237 esult of a failure to undergo apoptosis when tissue repair is complete, lead to pathological fibrosis

238 terleukin-10-mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan m

239 Macrophage participation in inflammation or tissue repair is directed by various extracellular signa

240 The use of stem cells to support tissue repair is facilitated by loading of the therapeut

241 isturbances are present during this process, tissue repair is impaired.

242 Clinically, such compromise in tissue repair is likely to increase wound recidivism.

243 r injury influence cellular behaviors during tissue repair is not well understood.

244 biomaterial scaffold (bioscaffold) for soft tissue repair is presented.

245 riostin, a matricellular protein involved in tissue repair, is markedly overexpressed by cyst epithel

246 may contribute to the control of damage and tissue repair, its persistent activation may result in t

247 ells upon tissue damage, shaping the overall tissue repair kinetics.

248 In contrast, increased percentages of tissue-repairing M2-like microglia, along with elevated

249 g executioner caspase activation is a normal tissue repair mechanism usurped to promote oncogene-driv

250 -inflammatory signals and enhance endogenous tissue repair mechanisms.

251 ulation of innate immunity, and promotion of tissue repairing mechanisms.

252 However, the current standard of care soft tissue repair meshes for hernia repair is highly inflamm

253 vity of CD271+ MSCs and improved early stage tissue repair of osteochondral lesions when transplanted

254 m due to their current clinical use for soft tissue repair, off-the-shelf availability, and zero auto

255 t promise as potential strategies to achieve tissue repair or regeneration and to attain therapeutic

256 eplacement of dead cells to the promotion of tissue repair or tissue remodeling in the affected site.

257 differently to normal tissue homeostasis, to tissue repair, or when challenged to expand ex vivo or t

258 occurs physiologically in wound healing and tissue repair, pathological lymphangiogenesis has been i

259 tress that elicits an immune system-mediated tissue repair pathway in tendons and ligaments.

260 d post-injury), biological processes include tissue repair pathways with upregulated genes related to

261 tion is necessary during the early phases of tissue repair, persistent inflammation contributes to fi

262 ving the production of cytokines involved in tissue repair (PGE(2) , IL-10) generally impaired by fre

263 dividing BMDMs promotes an anti-inflammatory tissue-repair phenotype in these cells.

264 Limited understanding of cardiac tissue repair process hampers the development of effecti

265 ogical processes in the radiation damage and tissue repair process.

266 s to improve stem cell function and optimize tissue repair processes.

267 13 together with apoptotic cells induced the tissue repair program in macrophages.

268 lex anti-inflammatory, immunomodulatory, and tissue-repair properties of MSCs.

269 d state, exhibiting neither bactericidal nor tissue-repairing properties.

270 l communication pathway with implication for tissue repair, regeneration, and cancer.

271 t that removes damaged tissues to facilitate tissue repair/regeneration.

272 ke macrophages highly expressed wide-ranging tissue repair-related genes.

273 Successful tissue repair requires the activities of myeloid cells s

274 ferative diseases are driven by dysregulated tissue repair responses and are a major cause of morbidi

275 ition of eNOS attenuates angiogenesis during tissue repair, resulting in delayed wound closure.

276 d IL-17 responses, and failed to orchestrate tissue repair, resulting in severe graft fibrosis and ab

277 sing a novel two-stage warping pipeline with tissue repair step, voxel-by-voxel rate of change maps w

278 ation with reduced infarct size and enhanced tissue repair (strengthened connective tissue formation,

279 During normal tissue repair, stromal niche signals, often Hedgehog-ind

280 ight neural/stromal/immune-cell crosstalk in tissue repair, suggesting future therapeutic approaches.

281 cancellous bone-like' printable implants for tissue repair that contain stem cells and controlled-rel

282 ariety of processes, including host defense, tissue repair, the pathogenesis of inflammatory disease

283 opulations of T lymphocytes known to mediate tissue repair, their reparative mechanisms, and the dise

284 regenerative ability is critical to advance tissue repair therapies.

285 m cells of skeletal muscle, are required for tissue repair throughout life.

286 n, eliminates cancerous cells, and regulates tissue repair, thus serving a critical role in homeostas

287 Macrophage plasticity is critical for normal tissue repair to ensure transition from the inflammatory

288 (ICE), regulates antimicrobial host defense, tissue repair, tumorigenesis, metabolism and membrane bi

289 ti-inflammatory signaling is associated with tissue repair, understanding the signaling mechanisms do

290 and repair macrophages is indispensable for tissue repair upon acute sterile injury.

291 Tissue repair usually requires either polyploid cell gro

292 by which cell-free CD34Exo mediates ischemic tissue repair via beneficial angiogenesis.

293 After injury, tissue repair was achieved through transient increases i

294 e an initial inflammatory phase is vital for tissue repair, we investigated the role of TLR4-regulate

295 that wound-induced polyploidization enables tissue repair when cell division is not a viable option.

296 a critical role in the inflammatory phase of tissue repair, where its dynamic plasticity allows this

297 g lipid mediators involved in resolution and tissue repair, whose intracellular signaling remains of

298 mation modulating polymer scaffolds for soft tissue repair with minimal postsurgical complications is

299 defense against infection and is involved in tissue repair, wound healing, and clearance of apoptotic

300 ers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in viv