ライフサイエンスコーパス: tissue-resident

1 one of which recirculates while the other is tissue resident.

2 Tissue resident adult stem cells are known to participat

3 sequences associated with global monocyte or tissue-resident alveolar macrophage depletion.

4 In mouse models, depletion of tissue-resident alveolar macrophages (TRAMs) attenuated

5 are composed of two macrophage populations, tissue-resident alveolar macrophages and interstitial ma

6 After injury, tissue-resident alveolar macrophages are depleted, and m

7 the lung ameliorated lung fibrosis, whereas tissue-resident alveolar macrophages did not contribute

8 veolar macrophages differ significantly from tissue-resident alveolar macrophages in their expression

9 s, where they became increasingly similar to tissue-resident alveolar macrophages.

10 sphingosine-1-phosphate receptor 1 (S1P1)(-) tissue resident and CD69(-) S1P1(+) nonresident iNKT cel

11 We conclude that tissue-resident and circulating Fgfbp1-expressing cells

12 is restrained by the concerted activation of tissue-resident and circulating immune cells.

13 -specific T cells and their capacity to form tissue-resident and long-lived memory populations are le

14 PU.1 motif is similarly associated with both tissue-resident and monocyte-derived IL-4-induced access

15 emodeling in response to IL-4 stimulation in tissue-resident and monocyte-derived macrophages is not

16 Tissue-resident and recruited macrophages contribute to

17 s, followed by resolution and repair through tissue-resident and recruited macrophages.

18 tention is given to delineating the roles of tissue-resident and recruited monocyte-derived macrophag

19 The gut microbiota and its products impact tissue-resident and recruited myeloid cells that promote

20 Understanding the interplay between tissue-resident and systemic immune responses against tu

21 on of MAFB and MAFB-target genes in CD163(+) tissue-resident and tumor-associated macrophages.

22 ion in the absence of inflammation to become tissue-resident antigen presenting cells in vivo.

23 romote the differentiation of monocytes into tissue-resident antigen-presenting cells for activation

24 odies significantly restored the function of tissue-resident antiviral CD8(+) T(RM) cells in both the

25 the roles of Bhlhe40 in the circulating and tissue-resident arms of the immune system, with emphasis

26 cate TGF-beta-Smad2/3 signaling in activated tissue-resident cardiac fibroblasts as principal mediato

27 ing single-cell RNA sequencing, we show that tissue-resident cardiac macrophages differentially instr

28 entially orchestrated by distinct subsets of tissue-resident cardiac macrophages.

29 Tissue-resident CCR2+ macrophages promote monocyte recru

30 test the hypothesis that distinct subsets of tissue-resident CCR2- (C-C chemokine receptor 2) and CCR

31 In contrast, tissue-resident CCR2- macrophages inhibit monocyte recru

32 ther show that selective depletion of either tissue-resident CCR2- or CCR2+ macrophages before myocar

33 ather than residing in the lung as bona fide tissue-resident CD69(+) NK cells.

34 bits had higher frequencies of dysfunctional tissue-resident CD8(+) T(RM) cells.

35 uncover putative targets of SARS-CoV-2 among tissue-resident cell subsets.

36 ate sensing of changes in mechanical cues by tissue resident cells and convert the mechanical signals

37 y stimulated macrophages, one to assess lung tissue-resident cells (TR-Mphi) and two for their polari

38 creases in harnessing the potential power of tissue-resident cells for human health and disease, gamm

39 conventional natural killer cells (cNK) and tissue-resident cells often referred to as innate lympho

40 Group 2 innate lymphoid cells (ILC2s) are tissue-resident cells prominent at barrier sites.

41 ne homeostasis is maintained by a network of tissue-resident cells that continually monitor the exter

42 ctate the cytoarchitecture and fate of other tissue-resident cells to suppress their malignant outgro

43 N2-specific memory CD8(+) T cells, including tissue-resident cells, compared with placebo treatment.

44 ymphoid tissues, suggesting that some may be tissue-resident cells.

45 pathogen-specific memory T cells, including tissue-resident cells.

46 he three groups of macaques were observed in tissue-resident cells.

47 between macrophages, dying cells, and other tissue-resident cells.

48 during ontogeny and persist predominantly as tissue-resident cells.

49 Group 2 innate lymphoid cells (ILC2s) have tissue-resident competence and contribute to the pathoge

50 differentially infect and replicate in these tissue-resident DC and support the hypothesis that these

51 ult from driver mutation in a circulating or tissue-resident, DC-committed precursor.

52 ifferentiation and function of migratory and tissue-resident DCs, promoting disruption of T-cell acti

53 Tissue-resident dendritic cells (DCs) assemble actomyosi

54 e we identified a communication form between tissue-resident dendritic cells and niche cells that all

55 These data suggest that tissue resident effector cell numbers and low FcgammaR e

56 D8(+) T cells, including a Blimp1(hi)Id3(lo) tissue-resident effector cell population most prominent

57 ute a distinct population of circulating and tissue-resident effector T cells with immune-regulatory

58 ecular characteristics highly reminiscent of tissue-resident effector Tregs.

59 estigations to better understand the role of tissue resident eosinophils in different context.

60 MHCII(+) macrophages into macrophages with a tissue-resident F4/80(hi)CD206(-)PD-L2(-)MHCII(-)UCP1(+)

61 Mechanistically, loss of Smad2/3 from tissue-resident fibroblasts attenuated injury-induced ce

62 The fibrogenic response in tissue-resident fibroblasts is determined by the balance

63 ions are formed by poly-clonal proliferating tissue-resident fibroblasts.

64 Innate lymphoid cells (ILCs) are tissue-resident "first responders" of the immune system

65 ischemia-reperfusion injury and distinguish tissue-resident from recruited cell populations in combi

66 This is particularly true for tissue-resident gammadelta T cells.

67 d memory-like CD8(+) T cell populations with tissue-resident gene-expression signatures that shared f

68 Here, we report that tissue-resident group 2 innate lymphoid cells (ILC2) acc

69 mmatory Th17 cells elicited by pathogens and tissue-resident homeostatic Th17 cells elicited by comme

70 An increased number of functional tissue-resident HSV-specific CD8(+) T(RM) cells in laten

71 and functional maturation of circulating and tissue-resident human NK and CD8(+) T cells and promoted

72 ed with an increase in numbers of functional tissue-resident IFN-gamma(+) CRTAM(+) CFSE(+) CD4(+) and

73 that Il18r1(+) ILCs comprise circulating and tissue-resident ILC progenitors (ILCP) and effector-cell

74 We found that the homeostatic turnover of tissue-resident ILC1s is much slower than that of circul

75 ulating mature natural killer (NK) cells and tissue-resident ILC1s, the functional, phenotypic, and d

76 eview highlights our recent understanding of tissue-resident ILCs and the signals that regulate their

77 antigens directly modulate the responses of tissue-resident ILCs has remained unclear.

78 s is critically dependent on the function of tissue-resident immune cells and the differentiation cap

79 Tissue-resident immune cells are important for organ hom

80 ss-talk between the bronchial epithelium and tissue-resident immune cells controls the tissue microen

81 h tissue site in the body can contain unique tissue-resident immune cells from both the lymphoid and

82 obes modulate the maturation and function of tissue-resident immune cells in the CNS.

83 But what about the myriad tissue-resident immune cells that are critical to this b

84 Mast cells are unique tissue-resident immune cells that express an array of re

85 a constitute a highly specialized network of tissue-resident immune cells that is important for the c

86 g-term hematopoietic stem cells give rise to tissue-resident immune cells that persist throughout adu

87 Mast cells are tissue-resident immune cells that play pivotal roles in

88 lammation and discover both infiltrating and tissue-resident immune cells to be visible without any l

89 a critical window for distribution of innate tissue-resident immune cells within developing organs.

90 ifically target epithelial cells also affect tissue-resident immune cells.

91 space and time give rise to circulating and tissue-resident immune cells.

92 indicating that human CD49e(-) NK cells are tissue resident in the liver.

93 omatic cell nuclear transfer, have increased tissue resident iNKT cells.

94 The CD69(+) S1P1(-) tissue-resident iNKT cells highly express P2X7 and are e

95 Tissue-resident iNKT cells maintain tissue homeostasis a

96 Group 2 innate lymphoid cells (ILC2) are tissue-resident innate effector cells that can mediate a

97 8(+) T cells and promoted the development of tissue-resident innate lymphoid cell (ILC) subsets.

98 s a crucial regulator of a growing number of tissue-resident leukocyte populations.

99 n parallel with shifts in the composition of tissue-resident leukocytes and with an accumulation of a

100 Eosinophils are circulating and tissue-resident leukocytes that have potent proinflammat

101 Group 2 innate lymphoid cells (ILC2) are tissue-resident, long-lived innate effector cells implic

102 ites, such as the skin, gut, and lung, these tissue-resident lymphocyte populations are ideally posit

103 rize recent advances in the understanding of tissue-resident lymphocyte populations, review the avail

104 Tissue resident lymphocytes are present within many orga

105 sites in multiple organs, enriched for these tissue-resident lymphocytes and dendritic cells, as well

106 Innate lymphoid cells (ILCs) are tissue-resident lymphocytes categorized on the basis of

107 Tissue-resident lymphocytes play a key role in immune su

108 Innate lymphoid cells (ILCs) are tissue-resident lymphocytes that promote immunity to pat

109 s is critically dependent on the function of tissue-resident lymphocytes, including lipid-reactive in

110 role for S1PR2 in restraining the egress of tissue-resident lymphocytes.

111 rrogate the cardiac microvasculature and the tissue resident macrophage distribution and better infer

112 Most tissue-resident macrophage populations develop during em

113 The inflammatory response, modulated both by tissue resident macrophages and recruited monocytes from

114 In the context of tissue resident macrophages, Egr2 expression is most pro

115 atory reactions, besides self-replication of tissue resident macrophages.

116 a also have a unique genetic signature among tissue resident macrophages.

117 Most tissue-resident macrophages (Mphis) are believed to be d

118 The discovery of a fetal origin for tissue-resident macrophages (trMacs) has inspired an int

119 Tissue-resident macrophages (TRMs) populate all tissues

120 in mouse EMPs results in clonal expansion of tissue-resident macrophages and a severe late-onset neur

121 These findings show that adult tissue-resident macrophages and innate-like lymphocytes

122 poptotic cells impaired the proliferation of tissue-resident macrophages and the induction of anti-in

123 he validity of the MPS model and argued that tissue-resident macrophages are a separate lineage seede

124 We propose that tissue-resident macrophages are metabolically poised in

125 The genes required for quiescence of tissue-resident macrophages are not well understood.

126 Monocyte-derived and tissue-resident macrophages are ontogenetically distinct

127 re is a shift in macrophage ontogeny whereby tissue-resident macrophages are predominately replaced b

128 Tissue-resident macrophages are the most abundant immune

129 ese results identify the fetal precursors of tissue-resident macrophages as a potential cell-of-origi

130 e identified both inflammatory monocytes and tissue-resident macrophages as sources of TAMs.

131 , ATG16L1 or ATG7-in mediating quiescence of tissue-resident macrophages by limiting the effects of s

132 Tissue-resident macrophages can originate from embryonic

133 In agreement with these findings, adipose-tissue-resident macrophages did not express TH.

134 Adult bone marrow monocytes can give rise to tissue-resident macrophages during infection or inflamma

135 We found that tissue-resident macrophages from healthy epididymal whit

136 Microglia are tissue-resident macrophages implicated in central nervou

137 rve both embryo-derived and monocyte-derived tissue-resident macrophages in a G1-like phase at freque

138 ghlight the fundamental role of microglia as tissue-resident macrophages in neuronal health.

139 Tissue-resident macrophages in the mammary gland are fou

140 have highlighted the profibrotic activity of tissue-resident macrophages in the pancreatic cancer mic

141 Organ-specific functions of tissue-resident macrophages in the steady-state heart ar

142 Microglia are the tissue-resident macrophages of the brain and spinal cord

143 Microglia are tissue-resident macrophages of the CNS that orchestrate

144 The dura mater is rich in tissue-resident macrophages originally derived from yolk

145 al multiplex microscopy, we report here that tissue-resident macrophages rapidly sense the death of i

146 Tissue-resident macrophages require specific milieus for

147 Different lineages of tissue-resident macrophages respond divergently to micro

148 In the meninges, a unique subset of tissue-resident macrophages serves as a sentinel populat

149 Here we demonstrate that peritoneal tissue-resident macrophages use an active inhibitory pat

150 Microglia and other tissue-resident macrophages within the central nervous s

151 established for some immune cells, including tissue-resident macrophages, and blood-derived cells inc

152 Microglia, the brain's tissue-resident macrophages, contribute to the developme

153 ancreatic epithelium, as well as a subset of tissue-resident macrophages, expresses the prolactin-rec

154 ting of a distinct population of CX(3)CR1(+) tissue-resident macrophages, form an internal immunologi

155 th M2/M2-like molecules in subsets of normal tissue-resident macrophages, infiltrating macrophages fr

156 flammatory macrophages can adopt features of tissue-resident macrophages, or what mechanisms might me

157 function in maintaining immune quiescence of tissue-resident macrophages, resulting in genetically pr

158 ne expression across neural and conventional tissue-resident macrophages, we identified transcripts t

159 enance of the cellular phenotype of injected tissue-resident macrophages.

160 eviously unrecognized control of IL-1beta in tissue-resident macrophages.

161 al macrophages (LPMs), but not that of other tissue-resident macrophages.

162 ells, tumor-infiltrating lymphoid cells, and tissue-resident macrophages.

163 However, they fail to mimic all aspects of tissue-resident macrophages.

164 distinct from monocytes and their respective tissue-resident macrophages.

165 now considered to be a specialized subset of tissue-resident macrophages.

166 C-derived monocytes from microglia and other tissue-resident macrophages.

167 rs provide new insight into efferocytosis by tissue-resident macrophages.

168 Our findings indicate that human tissue-resident MAIT cells in the kidney may contribute

169 ased kidney tissues, detecting expression of tissue-resident markers (CD103/CD69) on MAIT cells in bo

170 ice supported the population of mature human tissue-resident mast cells and basophils.

171 MBC subsets from multiple tissues revealed a tissue-resident MBC gene signature as well as gut- and s

172 We defined a tissue-resident MBC phenotype that was predominant in th

173 s in rectal secretions and with SIV-specific tissue resident memory B cells.

174 Tissue resident memory CD8(+) T cells (Trm) are poised f

175 was enriched in regulatory T cells (Tregs), tissue resident memory CD8(+) T cells (TRMs), resident n

176 ting cytokines and are phenotypically of the tissue resident memory state in utero.

177 mory T cells and the most recently described tissue resident memory T (T(RM)) cells.

178 cells in the insulitic lesions to display a tissue resident memory T cell (TRM) (CD8(+)CD69(+)CD103(

179 Such CD8(+) tissue resident memory T cells (T(RM)) are critical for

180 Skin tissue resident memory T cells (T(RM)) provide superior

181 Tissue resident memory T cells (Trm) form in the skin in

182 tion and find that the majority of cells are tissue resident memory T cells with high levels of CD69

183 us are the emergence and characterization of tissue resident memory T cells, manipulation of T cell m

184 insight into the mechanisms of induction of tissue-resident memory (T(RM)) CD8(+) T cells (CD8(+) T(

185 Tissue-resident memory (T(RM)) CD8(+) T cells in the CNS

186 Tissue-resident memory (Trm) CD8(+) T cells mediate prot

187 nd that chronic infection drove MNV-specific tissue-resident memory (Trm) CD8(+) T cells to a differe

188 progenitors, and expansions of activated and tissue-resident memory (TRM) CD8+ T lymphocytes, myeloid

189 Tissue-resident memory CD8 T (T(RM)) cells are a unique

190 Tissue-resident memory CD8(+) T (Trm) cells mediate pote

191 Tissue-resident memory CD8(+) T (Trm) cells share core r

192 Tissue-resident memory CD8(+) T cells (T(RM) cells) are

193 Tissue-resident memory CD8(+) T cells (T(RM)s) confer ra

194 Tissue-resident memory CD8(+) T cells (Trm) provide host

195 of effector memory CD8(+) T cells (TEM) and tissue-resident memory CD8(+) T cells (TRM), but not of

196 onic antigen-experienced lymphocytes such as tissue-resident memory CD8(+) T cells can respond rapidl

197 combat ocular herpes.IMPORTANCE HSV-specific tissue-resident memory CD8(+) T(RM) cells play a critica

198 nhanced generation of CD4 memory, especially tissue-resident memory in the lung, long-lived bone marr

199 bionts of immunized mice, demonstrating that tissue-resident memory is not required for vaccine-induc

200 Lung-derived CD8(+) T cells displayed tissue-resident memory phenotypes.

201 and a molecularly distinct Blimp1(lo)Id3(hi) tissue-resident memory population that subsequently accu

202 f latency and contract to a stable activated tissue-resident memory population.

203 High numbers of tissue-resident memory T (T(RM)) cells are associated wi

204 ells that transit between skin and blood and tissue-resident memory T (T(RM)) cells, which remain in

205 Tissue-resident memory T (Trm) cells are detrimental in

206 Tissue-resident memory T (TRM) cells persist indefinitel

207 vation of mucosal CD8+ T cells, particularly tissue-resident memory T (TRM) cells recognizing conserv

208 T cells showed characteristics of activated tissue-resident memory T (TRM) cells.

209 epidermis and form populations of long-lived tissue-resident memory T (TRM) cells.

210 r a role for monocyte-derived APC (MoAPC) in tissue-resident memory T cell (Trm) formation.

211 n of inflammatory DCs (CD1A(+)FCER1A(+)) and tissue-resident memory T cells (CD69(+)CD103(+)).

212 Tissue-resident memory T cells (T(RM) cells) are a novel

213 Tissue-resident memory T cells (T(RM) cells) are critica

214 Although tissue-resident memory T cells (T(RM) cells) have been s

215 pheral invariant NKT cells (iNKT) and CD8(+) tissue-resident memory T cells (T(RM)) express high leve

216 In recent years, tissue-resident memory T cells (T(RM)) have emerged as e

217 CD8(+)/CD103(+) tissue-resident memory T cells (TRM cells) accumulate in

218 CD8+ tissue-resident memory T cells (TRM cells) are poised at

219 These tissue-resident memory T cells (TRM) are preferentially

220 Tissue-resident memory T cells (TRM) have been shown to

221 sing body of evidence emphasizes the role of tissue-resident memory T cells (TRM) in the defense agai

222 r 4-1BB is important in the establishment of tissue-resident memory T cells (Trm) in the lung tissue

223 63hi/CD206hi Kupffer cells (KCs) and CXCR3hi tissue-resident memory T cells (TRM).

224 In adult mice, lung-localized, tissue-resident memory T cells (TRMs) mediate optimal pr

225 The presence of tissue-resident memory T cells at barrier tissues is cri

226 Previous work has shown that tissue-resident memory T cells can be established by "pu

227 infected mice displayed decreased numbers of tissue-resident memory T cells compared with H1N1-infect

228 ation and recall kinetics of circulating and tissue-resident memory T cells in mice infected with mur

229 CD4 tissue-resident memory T cells secrete interferon-gamma,

230 e knockouts, we uncover a multi-organ web of tissue-resident memory T cells that functionally adapt t

231 onal T cells, including the newly identified tissue-resident memory T cells, and whether such T cells

232 ce; however, despite the decreased number of tissue-resident memory T cells, H5N1 (2:6) was protected

233 a), which induces the expression of CD103 on tissue-resident memory T cells, has been implicated in H

234 ly recruit CD8(+) T cells and retain them as tissue-resident memory T cells, independently of local i

235 induction and maintenance of CD4(+)CD103(+) tissue-resident memory T cells, needed to replenish the

236 tumor microenvironment and similarities with tissue-resident memory T cells, which are more radio-res

237 ivo and augmented their differentiation into tissue-resident memory T cells.

238 epithelial cell states and a novel subset of tissue-resident memory T cells.

239 plastic intima, and minimized CD4(+)CD103(+) tissue-resident memory T cells.

240 promotes the accumulation of salivary gland tissue-resident memory T cells.

241 nAbs and cellular immunity, including CD8(+) tissue-resident memory T cells.

242 d the rapid erosion of pathogen-specific CD8 tissue-resident memory T cells.

243 elated positively with CD8(+)CD103(+)CD69(+) tissue-resident memory T cells.

244 ivation of mucosal CD8+T cells, particularly tissue-resident memory T(TRM) cells recognizing conserve

245 cells arise from memory cells and rejoin the tissue-resident memory T-cell pool after cessation of IL

246 allergic asthma, yet the mechanisms whereby tissue-resident memory Th2 (Th2 Trm) cells and circulati

247 functions, and finally to the development of tissue-resident memory.

248 Tissue-resident mesenchymal progenitors (MPs) also parti

249 ory reaction that includes activation of the tissue-resident microglia and recruitment of blood-deriv

250 ced differences in proportional abundance of tissue-resident microglia, infiltrating monocyte-derived

251 death post-infection and point to a role for tissue-resident MMs in limiting neuronal damage.

252 ndant use of these receptors in establishing tissue-resident monocytic cell populations.

253 scriptome identical to embryonically derived tissue-resident Mphis.

254 We identify that white adipose tissue-resident multipotent stromal cells (WAT-MSCs) can

255 n of inflammatory functions of recruited and tissue-resident Mvarphi.

256 A network of tissue-resident myeloid and lymphoid immune cells was ev

257 Microglia belong to a lineage of adult tissue-resident myeloid cells that develop during organo

258 ococcus pneumoniae in this organ mediated by tissue-resident MZ and RP macrophages and a protective r

259 and innervating nerves, PNECs, as prototype tissue-resident neuroendocrine cells, are at the center

260 The recent discoveries of tissue-resident NK cell developmental intermediates, non

261 Thus, these studies indicate that tissue-resident NK cells are evolutionarily conserved in

262 he phenotype and function of circulatory and tissue-resident NK cells in a unique cohort of SIV-contr

263 ent studies in mice indicate the presence of tissue-resident NK cells in certain organs, such as the

264 onal plasticity to differentiate into either tissue-resident or inflammatory Mphis, depending on micr

265 ival gammadeltaT cells is radioresistant and tissue-resident, persisting locally independent of circu

266 u has revealed a division of labor among the tissue resident phagocytes that sample them.

267 erns of interactions between neutrophils and tissue-resident phagocytes within the influenza-infected

268 Peritoneal MAIT cells displayed an activated tissue-resident phenotype, and this was corroborated by

269 ring ubiquitous TCRs display a dysfunctional tissue-resident phenotype.

270 also expressed CXCR3/CCR5/LFA-1 trafficking/tissue-resident phenotypes and consistently trafficked t

271 at have been described to contribute to this tissue-resident population in other organs, including in

272 er in vivo, we found a dramatically enlarged tissue-resident population surprisingly coexpressing sel

273 litis-associated CD8 T cells originated from tissue-resident populations, explaining the frequently e

274 ol of NK cell development and maintenance as tissue-resident populations, whereas mature, terminally

275 dly segregated into distinct circulating and tissue-resident populations.

276 nces in our understanding of the identity of tissue-resident progenitor populations in WAT made possi

277 view of endogenous pericytes as multipotent tissue-resident progenitors and suggest that the plastic

278 s mesenchymal stem cells (MSCs), multipotent tissue-resident progenitors with great potential for reg

279 onal properties, we found that only lymphoid-tissue resident Rorc(fm+) ILCs can suppress tumor growth

280 Innate lymphoid cells (ILCs) are tissue-resident sentinels that are essential for early h

281 ulate lymph nodes and intestines and exhibit tissue-resident signatures and site-specific adaptations

282 ne cells and the differentiation capacity of tissue-resident stem cells (SCs).

283 L effector functions mediated by a specific, tissue-resident subset of group I ILCs.

284 ssion and augments the cytotoxic activity of tissue-resident T and NK cells, which coincides with red

285 uman genital tract despite low CD8+ and CD4+ tissue-resident T cell (Trm cell) density are unknown.

286 Recently, tissue-resident T cells have been shown to mediate high

287 ffector memory T cells and CD103(high)CD8(+) tissue-resident T cells in TG of latently infected HLA-A

288 Thus, host tissue-resident T cells may play a previously unapprecia

289 ls (T(reg)) as well as other circulating and tissue-resident T cells.

290 the pathways guiding the differentiation of tissue-resident T(R) cell populations have not been well

291 Thus, we propose that tissue-resident T(R) cells develop in a multistep proces

292 y markers and a transcriptional signature of tissue-resident T(R) cells.

293 ic inflammation permanently reconfigures the tissue-resident TCRgammadelta(+) IEL compartment in CeD.

294 Besides lymphoid tissue-resident Tfh cells, CXCR5(+) circulating Tfh (cTf

295 Tissue-resident (TR) alveolar macrophages (APhi) are lon

296 eir differentiation into follicular Treg and tissue-resident Treg cells.

297 ced multiorgan immune toxicity by preserving tissue-resident Tregs in Rag 1-/- mice that received nai

298 de that depletes tumor-infiltrating, but not tissue-resident, Tregs, preserving antitumor effects whi

299 Here, we show that tissue-resident type 1 innate lymphoid cells (ILC1) serv

300 Swift production of interleukin (IL)-12 by tissue-resident XCR1(+) conventional dendritic cells (cD