ライフサイエンスコーパス: titer

1 rmentation (273-fold higher than the initial titer).

2 a 2-dilution increase in rapid plasma regain titer.

3 s, and marginal changes in AChR autoantibody titer.

4 to increase expression of Bik1 and bikaverin titer.

5 ong seven aphid clones differing in Buchnera titer.

6 were significantly associated with higher VN titer.

7 ells consistent with higher infectious virus titers.

8 , IRF5 hyperactivation correlated with dsDNA titers.

9 CP infusion did not alter recipient NAb titers.

10 lowest among those with the highest antibody titers.

11 ciation was observed after adjusting for HAI titers.

12 ng positive correlation with anti-RBD and VN titers.

13 onsistently increased VZV spread and progeny titers.

14 -RBD and anti-ECD IgG titers and in vitro VN titers.

15 lds, high volumetric productivities and high titers.

16 s opposed to few donors with singularly high titers.

17 e model, and dramatically lowered viral lung titers.

18 f vRNPs and the reduction of influenza virus titers.

19 m RSV plaque-reduction neutralizing antibody titer, 1:64).

20 vaccine; 20 (95%) shed vaccine (median peak titer, 3.5 log10 PFUs/mL with immunoplaque assay and 6.1

21 taM2-2/1030s vaccine (median peak nasal wash titers: 3.1 log10 PFU/mL by immunoplaque assay; 5.1 log1

22 s well as strong hemagglutination inhibition titers, a surrogate for neutralization of intestinal adh

23 ase of SARS-CoV-2-specific serum IgA and IgG titers after symptom onset.

24 increases in serum RSV-neutralizing antibody titers after the RSV season without RSV-MAARI.

25 , most of them also had lower or no antibody titer against the challenge antigen.

26 pancreas, decreased circulating autoantibody titers against citrullinated glucose-regulated protein 7

27 utralization and hemagglutination inhibition titers against different clades of H1N1 subtype influenz

28 Pre-immunization titers against H3 HA-pseudoviruses containing egg-adapti

29 ome group had the highest levels of antibody titers against hepatitis B vaccine.

30 pneumococcal immunoglobulin G (IgG) antibody titers against the 7 serotypes shared by PCV7, PCV13, an

31 The cPRA per titer also risk-stratified candidates for trial inclusio

32 nated cryptococcosis occurred in 7 (22%) low-titer and 15 (47%) high-titers cases (P = 0.064).

33 TMV presentation improved titer and avidity of repeat-specific Abs compared to a n

34 nary function occurs 4 days after peak viral titer and correlates with infiltration of monocytes, neu

35 evaluated, namely level of infection, virus titer and genome copy number.

36 bioderivatization had a higher molar product titer and product yield, as well as improved cellular gr

37 stantial improvements can be made in protein titer and purity through large-scale HCP deletion, provi

38 There was an association between IgG1 titer and SNP rs3901533 of dectin-1, the beta-glucan rec

39 r increases in DSA, which may be high or low titer and transient or persistent.

40 memory IgE response with elevated serum IgE titers and accumulation of IgE-producing PCs.

41 nd there may be an early benefit in antibody titers and activated CD8+ T cells by the administration

42 le exhibit significantly higher autoantibody titers and altered expression of the immune system, auto

43 iters waned with a half-life of 49 days, nAb titers and avidity increased over time for some individu

44 gA levels strongly correlated with serum IgA titers and blockade antibodies and remained elevated 3 m

45 cal inhibitors or gene silencing reduced MDV titers and cell-to-cell spread.

46 Both NAb titers and EIA detectable Abs are increased in patients

47 msters limits weight loss and decreases lung titers and evidence of pneumonia in the lungs.

48 son to determine neutralizing antibody (nAb) titers and for influenza virus sequencing, respectively.

49 Nab titers and immunoglobulin G levels were correlated in do

50 etween both plasma anti-RBD and anti-ECD IgG titers and in vitro VN titers.

51 th low to intermediate preinfection antibody titers and lowest among those with the highest antibody

52 Pre-F-specific antibody geometric mean titers and median frequencies of F-specific interferon g

53 h ovalbumin resulted in diminished serum IgE titers and reduced mast cell activation.

54 nza vaccines elicited similar neutralization titers and response rates, indicating that the cell-deri

55 was to assess the antipneumococcal antibody titers and seroprotection rates of allogeneic HCT recipi

56 independent of HIV status, sex, age, KSHV Ab titer, and KSHV-neutralizing activity.

57 es were included (32 each in low-titer, high-titer, and negative-titer groups).

58 cing serum antinuclear autoantibodies, dsDNA titers, and the number of circulating plasma cells, whic

59 ups for antibody repertoires, neutralization titers, anti-F binding antibodies (prefusion and postfus

60 Pertussis antibody titers are higher in acellular pertussis (aP)- than wP-v

61 We also show that titers are relatively stable for at least a period of ab

62 ound that the G614 variant grows to a higher titer as pseudotyped virions.

63 ally equivalent dengue serotype-specific NAb titers as the currently used schedule, and there may be

64 ated cPRA reduction, calculated per antibody titer, as a desensitization trial endpoint.

65 91.1%) were seropositive; antiviral antibody titers assayed by two pan-Ig assays increased during 2 m

66 bies vaccination induces acceptable antibody titers at a fraction of the dose.

67 urred in 22% of participants with high eAb-B titers at baseline compared with 35% with low or medium

68 e responses, including neutralizing antibody titers at levels comparable to those found in convalesce

69 culture-derived particles (HEVcc) with viral titers between 10(5) and 10(6) FFU/mL.

70 or boosting titers by >4-fold for those with titers between 1:8 and 1:362 at baseline.

71 (geometric mean titer) increase in blocking titers (BT50) and a 161-fold increase in GI.1-specific i

72 zations can increase serum anti-Env antibody titers but only transiently.

73 ositive (>1:8) after vaccination or boosting titers by >4-fold for those with titers between 1:8 and

74 fectious virus, with COPI-knockdown reducing titers by approximately 1,000-fold.

75 ression of the top ten ISGs attenuates virus titers by up to 1000-fold.

76 eral of these NiV DIP candidates reduced NiV titers by up to 4 logs in vitro.

77 This indicates that only changes >2 titers can be deemed clinically meaningful.

78 urred in 7 (22%) low-titer and 15 (47%) high-titers cases (P = 0.064).

79 nitial clinical cure were similar across eAb titer categories.

80 linical cure and rCDI were summarized by eAb titer category (low, medium, high) at each time point.

81 thy had significantly higher RSV-A and RSV-B titers compared to infants that subsequently contracted

82 S was beneficial and significantly increased titers compared to that of T590 variants but had no majo

83 ild disease that may evoke relatively low Ab titers compared with patients admitted to hospitals.

84 2 (42%) colonized infants had detectable NAb titers compared with zero non-TCD-colonized infants (P =

85 9 with high anti-receptor binding domain IgG titer convalescent plasma is efficacious in early-diseas

86 for transfusing COVID-19 patients with high-titer convalescent plasma.

87 uired cutoff of 12.0 for designation of high-titer convalescent plasma.

88 RS-CoV-2 spike (S) and nucleoprotein and nAb titers correlate with clinical scores.

89 Anti-VZV plasma antibody titers correlated positively with the number of VZV-spec

90 Viral titers could be further enhanced by an HEV variant harbo

91 The clinical significance of low-titer cryptococcal antigen (CrAg) by lateral flow assay

92 A/H1N1 and B strains in study 1, whereas the titers determined by HI were higher than those determine

93 The median (IQR) titer difference was 0 (0-1) from baseline to follow-up

94 ncreased anti-trimer antibody responses, but titer differences waned after two further doses.

95 ough 5-7 months after onset, whereas alpha-N titers diminished.

96 graft is exposed to rapid increases in high-titer donor-specific antibodies (DSA) that are most ofte

97 ial-scale fermentation, which is the highest titer ever reported.

98 ied symptomatic individuals with preexposure titers exceeding this threshold.

99 Higher initial tTGA titers, female sex, and a history of hypothyroidism and

100 d declines in viremia to undetectable plasma titers following cART initiation, infection of long-live

101 ntibodies rose in tandem with immunoglobulin titers following symptom onset, and positive percent agr

102 ties were able to significantly reduce virus titer for all viruses investigated, with the exception o

103 ion needed to reach a cPRA <98% was within 1 titer for replicates from the same sample, with 90% (36/

104 recovered patients develop adequate antibody titers for donation and the relationship between avidity

105 Our strategy could improve polyketide titers for pharmaceutical production.

106 G titers were greater than either IgM or IgA titers for S1, full-length S, and S-RBD in the overall p

107 The median CrAg titers for semiquantitative score categories (1+ to 4+)

108 We assessed neutralizing antibody titers for the four dengue serotypes (DENV) up to Month

109 d rise in virus-specific IgM or IgG antibody titers from acute- and convalescent-phase sera.

110 While titers generally decreased with time, anti-IFN-gamma aut

111 Cell-growth pathways are up-regulated in low-titer genotypes, while membrane trafficking, lysosomal p

112 d cytokine pathways are up-regulated in high-titer genotypes.

113 he 25-mug dose, the anti-S-2P geometric mean titer (GMT) was 323,945 among those between the ages of

114 bent assay anti-S-2P antibody geometric mean titer [GMT], 40,227 in the 25-mug group, 109,209 in the

115 Geometric mean titers (GMTs) and seropositivity rates were compared bet

116 in viral neutralization assay-geometric mean titers (GMTs) of neutralizing antibodies of the vaccine

117 each in low-titer, high-titer, and negative-titer groups).

118 A nAb titer >300 was generally associated with protection but

119 ivariable analyses showed that anti-GD2-IgG1 titer >= 150 ng/mL by week 8 was associated with favorab

120 were >3.0 U/mL (HemosIL-AcuStar-HIT-IgG) and titer >=16 (ID-H/PF4-PaGIA); cutoffs with 100% NPV were

121 Titers >= 1:8 were considered protective.

122 ons in children, hemagglutination inhibition titers >=1:20 were associated with a 32% (95% CI, 13-47%

123 tibody titers reactive with R. rickettsii at titers >=64, whereas 6.3% of donors from Oregon and Wash

124 hart review of all CRMP5 IgG-positive (serum titer, >1:240) patients seen between 2001 and 2017.

125 ting, 96 cases were included (32 each in low-titer, high-titer, and negative-titer groups).

126 In high-titer hosts, both bacteriocytes and symbionts show eleva

127 pressed in bacteriocytes of low- versus high-titer hosts: Cell-growth pathways are up-regulated in lo

128 As a result, the GlcNAc titer in a 15-l fed-batch bioreactor increased from 59.9

129 ot generate a robust neutralization antibody titer in comparison to the HSV-1 0DeltaNLS-vaccinated wi

130 e, sufficiently attenuated, and grow to high titer in cultured cells, while retaining high immunogeni

131 ct viral types that differ 100-fold in viral titer in infected individuals, with similar differences

132 ly significant reduction (P < 0.05) in viral titer in liver and spleen at day 5 postinfection (d p.i.

133 Upon mating, 20HE titer in ovaries and hemolymph are increased and act on

134 te-term abortion, at which time the pathogen titer in placental tissue can exceed one billion bacteri

135 zed for measles do not show a protective IgG titer in the 10 years after vaccination.

136 How SARS-CoV-2 is able to achieve high titer in the absence of symptoms remains unclear.

137 The mortality rate and viral titer in the brains of mice inoculated intraperitoneally

138 ow titers in 6 of 12 instances and increased titers in 2 cases.

139 =1:5 titers (n = 21) showed persistently low titers in 6 of 12 instances and increased titers in 2 ca

140 rotein immunoglobulin G levels, neutralizing titers in a pseudotyped lentiviral assay, and the presen

141 nfection is not solely dependent on high NAb titers in affected subjects, and this recovery process i

142 and mutant viruses did not replicate to high titers in all infected animals.

143 High cryptococcal antigen (CrAg) titers in blood are associated with subclinical meningit

144 human cells to levels that are comparable to titers in chicken embryo fibroblasts.

145 -M (IgM), and in vitro neutralizing antibody titers in COVID-19 patients.

146 We measured NAb titers in CP and in patients with acute COVID-19 before

147 rders of magnitude higher levels of antibody titers in mice that neutralize pseudovirus cell entry, b

148 er of Ag-specific CD4(+) T cell count and Ab titers in mice.

149 dose-dependent SARS-CoV-2 specific antibody titers in mouse sera, as well as robust neutralization o

150 toward higher anti-circumsporozoite antibody titers in participants protected against infection.

151 SARS-CoV-2-specific serum IgA titers in patients with mild COVID-19 were often transie

152 5 of 12 patients demonstrated high viral RNA titers in the liver, kidney, or heart.

153 SARS-CoV-2, and this resulted in high viral titers in the lung, lung pathology, and weight loss.

154 the H5N2-R3 virus replicated to the highest titers in the lung.

155 ravir significantly reduced infectious virus titers in the lungs and markedly improved lung histopath

156 The antibody titers in the prechallenge sera were not predictive of p

157 ted from lethal mousepox and controlled MCMV titers in the spleen.

158 se cytomegalovirus (MCMV) displayed elevated titers in the spleen.

159 WV isolate-T. tabaci isoline pairings, virus titers in the thrips vector were significantly lower in

160 his study characterizes differences in virus titers in the vector among TSWV isolate-T. tabaci isolin

161 Higher Ab titers in these assays associated with more-severe disea

162 onses to GI.1 with a 30-fold (geometric mean titer) increase in blocking titers (BT50) and a 161-fold

163 The (H1N1)pdm09 titer increased in 2017-2018, indicating more efficient

164 After the second vaccination, the titers increased (day 57 GMT, 299,751, 782,719, and 1,19

165 ts obtained from the centers exhibiting high titers, indicative of a potential regional phenomenon am

166 DENV1, DENV3, and ZIKV disease, intermediate titers induced by previous ZIKV or DENV infection enhanc

167 ured neurons, exceptionally pure intact high-titer infectious prions are not directly neurotoxic.

168 In conclusion, determining the cPRA per titer is a reliable approach to simplify complex antibod

169 The derived CMV titer is normalised against the total protein concentrat

170 elationship between avidity and neutralizing titers is currently not well understood.

171 n the heterologous viral vector + nAb group, titers <300 were sufficient.

172 st-time positive CrAg results with low serum titers (<=1:10) at two medical centers (Los Angeles, CA)

173 Low-serum CrAg titers (<=1:10) correlated with cryptococcal disease in

174 nalyzed in relation to preinfection antibody titer (measured by inhibition enzyme-linked immunosorben

175 Follow-up testing in patients with <=1:5 titers (n = 21) showed persistently low titers in 6 of 1

176 sociation of avidity and a high neutralizing titer (NT) were also assessed in donors using modified P

177 ti-EBOV GP immunoglobulin G titers with peak titers observed on Day 35 representing 498- to 754-fold

178 T2 band) results were compared with IMMY LFA titers obtained through serial dilution.

179 n anti-spike protein receptor binding domain titer of >=1:1350.

180 alse-negative result by CrAgSQ (n = 1) had a titer of <1:5, while the sample with a false-positive re

181 respiratory tract T cell responses but a low titer of Abs.

182 Application of ddTAG increased the titer of avermectin B(1a) by 50% to 9.31 g l(-1) in a 18

183 en modifying enzymes, leading to an improved titer of bikaverin at 202.75 mg/L with flask fermentatio

184 ially diluted in triplicate to determine the titer of individual human leukocyte antigen (HLA) antibo

185 Changes in the titer of JHSB3 were studied during the 10-day long molti

186 We quantified the titer of Lso haplotype A and B in adult psyllid guts aft

187 i.m.-immunized pigs generated a high titer of neutralizing Abs but poor T cell responses, whe

188 With all enhancing elements combined, the titer of pseudotyped HIV-1 particles reached almost 10(6

189 rgies were successful at inactivating a high titer of SARS-CoV-2.

190 Notably, the titer of the IgG in wild-type animals could be increased

191 olating from the test samples, the projected titer of virus particles necessary for the detection of

192 g antibodies with an endpoint geometric mean titer of ~415 against replicative virus, comparing favor

193 Of all donors, 37% lacked VN titers of >=160.

194 dults found 73 individuals with anti-ECD IgG titers of >=1:50 and strong positive correlation with an

195 results were obtained for samples with IMMY titers of <=1:160.

196 sing the hpaB and hpaC genes, we achieved HT titers of 1.15 +/- 0.05 mg/L and 4.6 +/- 0.9 mg/L in a m

197 is of neutral lipids to alka(e)nes and reach titers of 1.47 g/L from glucose.

198 inhibitory dilution (ID(50)) geometric mean titers of 501 in the 10-mug dose group and 3481 in the 1

199 Using ddTAG we increased the titers of actinorhodin, jadomycin B, oxytetracycline and

200 We compared titers of antibodies against A/H1N1, A/H3N2, and B influ

201 tigen to form plasmablasts that secrete high titers of germline-encoded IgM autoantibody and hypermut

202 Mice with initially high titers of HBV and knockdown of HBV antigen expression, b

203 Although vaccinated birds had higher titers of hemagglutination-inhibiting (HI) antibodies ag

204 The immunologic study revealed high titers of IgG autoantibodies in serum and cerebrospinal

205 vered patients (10 out of 49) with no or low titers of NAbs against the virus.

206 late-recovered patients was observed in the titers of nasal wash antibodies, especially binding to t

207 One of these factors is the presence and titers of neutralizing Abs (NAbs) in infected people.

208 be necessary for selecting donors with high titers of neutralizing activity for infusion into patien

209 w that primary ZIKV infection generates high titers of neutralizing antibodies that protect from dete

210 coproteins efficiently; however, much higher titers of pLV-G particles were produced.

211 ng activity, as well as significantly higher titers of RSV-specific mucosal IgA antibodies.

212 ith the vectors induced 7- to 15-fold higher titers of RSV-specific serum antibodies with high neutra

213 ontrast, SARS-CoV-2 infection induced higher titers of SARS-CoV-2 S-reactive IgG antibodies targeting

214 Very high titers of SARS-CoV-2-specific serum IgA were correlated

215 , with some centers exhibiting 3-5 times the titers of the others.

216 Concomitantly, we measured infectious titers of these same rNDV samples at different ionic str

217 rray device that is preassembled with custom titers of various antibiotics and splits bacterial sampl

218 e showed the effect of preinfection antibody titer on disease severity was mediated by viral load for

219 t to perform, as simple measurements like Ab titer only partly correlate with protection.

220 Kinetics of antibody titers over time among study groups were examined.

221 ly (P < .0001), and increased serum antibody titers (P < .01), whereas control mice did not.

222 aseline compared with 35% with low or medium titers (P = .015).

223 Average titers peaked on day 7 and declined toward day 14 (P = .

224 neuraminidase inhibition, and stalk antibody titers; peripheral blood leukocyte host gene expression

225 vaccinees had >=4-fold increases in antibody titers postsurveillance without RSV-MAARI, indicating an

226 although high preexisting anti-DENV antibody titers protected against DENV1, DENV3, and ZIKV disease,

227 High titer, rate, yield (TRY), and scalability are challengin

228 uction of 1,5-pentanediol from glucose, with titers reaching 1.41 and 0.97 g l(-1), respectively.

229 nors (n = 1493), 11.1% demonstrated antibody titers reactive with R. rickettsii at titers >=64, where

230 Whereas there was no difference in the virus titer recovered from the cornea comparing vaccinated mic

231 RSV severity was correlated with antibody titers, reduced T and B cells, dysregulated innate immun

232 ften transiently positive, whereas serum IgG titers remained negative or became positive 12 to 14 day

233 l resistance phase, during which the culture titer remains static, as if the chromosome has to accumu

234 Because virus titers resulting from sampling downstream of the UV-C re

235 A high-titer SARS-CoV-2 remnant patient specimen was spiked int

236 nts with severe COVID-19, with very high IgA titers seen in patients with severe acute respiratory di

237 VE estimate from cases identified by single-titer serology is misclassification arising from limited

238 tion between preinfection anti-DENV antibody titer, serum viral load, and disease severity, and provi

239 bulin G1 [IgG1] and IgM) and anti-GD3 (IgG1) titers showed notable increases following the initiation

240 negative SARS-CoV-2-specific serum antibody titers showed SARS-CoV-2-specific IgA in mucosal fluids

241 -DeltaI177L-infected animals had low viremia titers, showed no virus shedding, and developed a strong

242 f about 5 months and that anti-spike binding titers significantly correlate with neutralization of au

243 SARS-CoV/SARS-CoV-2 cross-reactive antibody titers specific for the receptor-binding domain.

244 we recommend the assessment of specific IgG titers starting from 24 months to decide for further dos

245 CryptoPS low-titer (T1 band) and high-titer (T2 band) results were co

246 CryptoPS low-titer (T1 band) and high-titer (T2 band) results were compared with IMMY LFA tite

247 Total SARS-CoV-2 antibody titers tended to be higher in the convalescent plasma gr

248 nt in cycle threshold value across all viral titers tested was 3.1.

249 ably is more cell associated and has a lower titer than other alphaherpesviruses, such as herpes simp

250 Waning immunity cases had higher IgG titers than indeterminate cases (mean optical density va

251 -negative children had higher geometric mean titers than mothers of KSHV-positive children; however,

252 AT1 phosphorylation and grew to 2-log-higher titers than wild-type virus in human Caco-2 cells and si

253 , 9 of 20 vaccinees had increases in the RSV titer that were significantly greater than those in 8 of

254 t E1E2 vaccine antigen induces high-antibody titers that are insufficient to neutralize diverse HCV i

255 e vaccination with JENVAC induces protective titers that persist up to 1 year.

256 ecovered subjects had raised significant NAb titers, there is a substantial number of recovered patie

257 able viremia, and high neutralizing antibody titers throughout the disease course.

258 Postvaccination neutralizing antibody titers to 3c2.A and 3c2.A2 were higher in Flublok recipi

259 Postvaccination titers to 3c2.A and 3c2.A2 were similar in Flublok and F

260 Postvaccination neutralizing antibody titers to H1N1 were similar among the different vaccine

261 All vaccines boosted titers to HA with egg-adaptive substitutions, suggesting

262 the United States was surveyed for antibody titers to hepatitis A virus (HAV), measles virus (MeV),

263 gG2c antibodies and for durable neutralizing titers to influenza.

264 nical illness, a marked increase in antibody titers to most EBOV proteins and affinity maturation to

265 egative population had significantly greater titers to the circulating 3C.2a2.

266 gative and positive patients had greater nAb titers to the egg-adapted vaccine virus compared to the

267 ncreased virulence compared to the low viral titer type.

268 Strikingly, the animal with the low-titer vaccine-induced anti-SIVmac239 NAb response acquir

269 This relationship is dynamic; Buchnera titer varies within individual aphids and among differen

270 The HIV-1 virulence factor Nef promotes high-titer viral replication, immune escape, and pathogenicit

271 The higher titer viral type suppresses the host-immune system and a

272 cohorts as well as in patients with high NAb titers, viral Ag binding Abs were detectable in EIA test

273 tion between preinfection anti-DENV antibody titers, viral load, and disease severity among 133 dengu

274 Whereas overall RBD-specific serum IgG titers waned with a half-life of 49 days, nAb titers and

275 glutaminase immunoglobulin A (anti-t-TG-IgA) titer was assessed.

276 infected patients, each log2 increase in nAb titer was associated with an average 0.2 log10 decrease

277 Input virus titer was not correlated with SMV recovery.

278 nt between detection of IgG and neutralizing titers was >93%.

279 A broad range of anti-HAV Ig plasma titers was observed among these centers, with some cente

280 Therefore, CLas incidence and titer were higher in the head-thorax of adults than in n

281 The elevated BAFF and ANA titers were also detected in human patients with primary

282 Importantly, elevated anti-HAV Ig titers were broadly observed across plasma units obtaine

283 rase chain reaction and area under the curve titers were determined.

284 s between HI- and MN-derived log-transformed titers were examined using different statistical techniq

285 Longitudinal KSHV titers were fairly stable over time, although serorevers

286 IgG titers were greater than either IgM or IgA titers for S1

287 of the disease, and in older patients the Ab titers were heightened.

288 Ab titers were measured using ELISA in healthy women (n = 1

289 and pre- and postsurveillance serum antibody titers were monitored.

290 Preexisting anti-NA antibody titers were most predictive of reduced influenza disease

291 an death times (MDT), and the virus-shedding titers were significantly lower than those of the sham-v

292 Antitetanus immunoglobulin G titers were similar between groups.

293 H3N2 and influenza B titers were similar between seasons.

294 Maternal and infant RSV titers were strongly correlated.

295 Twenty-seven patients with low CrAg titers were treated with antifungal therapy and 22 (81%)

296 crease in GI.1-specific immunoglobulin (Ig)G titers when compared with baseline.

297 rgD-2 had significantly higher neutralizing titers, whereas those elicited by DeltagD-2 had signific

298 ssay reliably detected individuals with high titers, which are associated with poor outcomes.

299 id increase in anti-EBOV GP immunoglobulin G titers with peak titers observed on Day 35 representing

300 loss of an enterovirus (CVB3/28) infectious titer, with little effect on nearly identical mutant str