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1 ity to be safe, effective, reproducible, and titratable.
2 ammonium excretion, citrate absorption, and titratable acid excretion to the same levels in Tg/Tg:ET
5 f chromaticity L(*) and h( degrees ) values, titratable acid, total soluble solids, total soluble sug
6 hysicochemical analyses showed variations in titratable acidity (0.19-0.51 %), alcohol (9.50-11.97 %)
7 ost suitable values for weight loss (2.22%), titratable acidity (0.45% citric acid), and repining ind
15 ated flow pH-method for the determination of titratable acidity (TA) in edible oil without titration
17 oncentration, total soluble solids (TSS) and titratable acidity (TA) were evaluated after 0, 25 and 5
19 olorimetry, mechanical texture analysis, pH, titratable acidity (TA), and soluble solid (SS), soluble
20 tion was paid to total soluble solids (TSS), titratable acidity (TA), colour, free amino acids (FAA),
21 racterized for soluble solids content (SSC), titratable acidity (TA), glucose, fructose, sucrose, mal
22 pulp colors, firmness, soluble solids (SS), titratable acidity (TA), SS/TA ratio, sugars, ascorbic a
23 pulp colors, firmness, soluble solids (SS), titratable acidity (TA), SS/TA ratio, sugars, ascorbic a
25 icochemical characterisation analysis (total titratable acidity (TA), total soluble solids (TSS), TSS
26 ted to conventional methodologies: pH, total titratable acidity (TA), total soluble solids, microbial
30 of homogenized raw apples can anticipate the titratable acidity (the residual predictive deviation (R
32 grees C, the coated fruits maintained better titratable acidity and antioxidant compounds compared to
35 hanges for degrees Brix, pH, water activity, titratable acidity and colour parameters in sonicated sa
36 cal scavenging activity, ascorbic acid, kept titratable acidity and firmness at high level than untre
38 s, pH and colour development increased while titratable acidity and fruit firmness decreased 14.7% an
39 decrease in the pH (<4.3) and an increase in titratable acidity and lactic acid (>0.37 % and > 1.7 g/
40 grees C, resulting in higher flesh firmness, titratable acidity and lesser physiological disorders, a
41 phenolic concentration, sugar concentration, titratable acidity and pH by modified partial least squa
43 igher soluble solids content, ascorbic acid, titratable acidity and sensory quality compared with con
46 oefficient revealed that reducing sugars and titratable acidity can influence the mineral bioaccessib
47 correspond to 15.15 and 15.71 degrees Brix; titratable acidity changed between 2.6 and 2.8g/L, citri
49 ine, GLRaV-3 infection prior to 2008 reduced titratable acidity compared with the uninfected control.
51 pH values of the samples decreased, whereas titratable acidity consistently increased during the sto
52 he highest contents of total soluble solids, titratable acidity content and ascorbic acid, 'Capri' ha
53 However, since Juliette exhibited a lower titratable acidity content than Albion, it consequently
54 C notably decreased, higher weight loss and titratable acidity content were observed at 5 degrees C
56 for color, non-enzymatic browning index and titratable acidity during storage and the quality of the
57 of water activity, total soluble solids, and titratable acidity exhibited non-significant increase up
58 n concentration were significantly lower and titratable acidity higher in berries collected from vine
59 ness and pitting resistance and decreases in titratable acidity loss and decay of both cultivars.
61 , presented a pH range from 3.89 to 4.17 and titratable acidity range from 0.798 to 0.826%, with good
62 s ranged from 4.0 to 6.0 by day 7, while the titratable acidity ranged from 2.5 to 5.0g/mL (P<0.05).
63 velopment, whereas the solid soluble content/titratable acidity ratio (SSC/TA) increases significantl
64 , while CH-CS-EOM-coated fruits showed lower titratable acidity than CH-CS-coated fruits at the end o
67 content of minerals, simple sugars, pH, and titratable acidity was assessed in the arabic, locust be
68 best results for weight loss, shrinkage, and titratable acidity were found to be 17.88%, 31.12%, and
70 he influences of product (soluble solids and titratable acidity) and process (temperature and heating
71 irmness, dry matter, soluble solids content, titratable acidity) and the levels of sugars, organic ac
72 ening, reduced phenolic extractability, high titratable acidity), and wine (altered sensory attribute
73 The physicochemical parameters (pH, Eh7, titratable acidity), sensory properties (color), and min
74 emical properties (i.e. pH, degrees Brix and titratable acidity), volatile and non-volatile component
78 xhibited greater microbial diversity, higher titratable acidity, and increased reducing sugar consump
79 acid, acidity, soluble solids concentration, titratable acidity, and repining index), phenolic enzyme
80 firmness, retarded losses in ascorbic acid, titratable acidity, and skin color, and reduced splittin
81 lic compounds, antioxidants, soluble solids, titratable acidity, ascorbic acid, glutathione, proline
82 degrees Brix, pH, water activity, viscosity, titratable acidity, cloud assessment and turbidity), ant
83 he yogurts were assessed for morphology, pH, titratable acidity, color, rheology and sensory analysis
84 n (Y-NE) were evaluated weekly regarding pH, titratable acidity, color, textural parameters, viscosit
85 fermentation patterns were observed for pH, titratable acidity, density, sugar consumption, and etha
87 zed changes in pH, total soluble solids, and titratable acidity, maintaining the fruits' texture and
88 moisture content, protein, fat, ash, pH and titratable acidity, mineral content (sodium, potassium,
89 rther, few changes in soluble solid content, titratable acidity, pH of the pulp as well as in sugar c
91 robial quality, weight, total soluble solid, titratable acidity, pH, total phenol and total anthocyan
93 ut provided fermented cocoa with similar pH, titratable acidity, reducing sugars and phenolic compoun
94 ction in colour indices, weight loss, pH and titratable acidity, reducing sugars, ascorbic acid, tota
95 ferences were found among treatments for pH, titratable acidity, soluble solids, total anthocyanin an
96 analyzed for their levels of soluble solids, titratable acidity, sugars, organic acids, vitamin C and
97 d higher dry matter, soluble solids content, titratable acidity, taste index, beta-carotene, ascorbic
98 The BIB packaging materials affected the titratable acidity, total and free SO2 and colour of win
99 n rate and sustained soluble solids content, titratable acidity, total phenol content and ascorbic ac
100 haracteristics (L( *), a( *), b( *), C( *)), titratable acidity, total phenolic, monomeric anthocyani
101 water was the highest, whereas water volume, titratable acidity, total soluble solids and total pheno
103 uced weight loss, minimal color changes, pH, titratable acidity, total soluble solids, and decreased
104 rs of all samples stored under pressure (pH, titratable acidity, total soluble solids, browning degre
106 al composition (i.e. the content of ethanol, titratable acidity, total sulfur dioxide, total phenolic
107 alyzed for pH, antioxidant properties, total titratable acidity, vitamin C, lycopene and total phenol
108 analysed for pH, total soluble solids, total titratable acidity, vitamin C, lycopene, total phenolic
109 analysed for pH, total soluble solids, total titratable acidity, vitamin C, lycopene, total phenolic
111 mpact of chlorogenic acids emerged in pH and titratable acidity, while the sensorial sourness appeare
115 group Cavendish ( degrees Brix;0.2, pH;4.73, titratable acidity; 0.56g/100g malic acid, total solids;
118 fat, amounts of macronutrients, minerals and titratable acids decreased during the ripening process.
119 Her2-expressing tumor cells, and afford dose-titratable activation of CAR-T cells ex vivo and complet
120 gested that RacE1 and RacE2 both possess two titratable active site residues important for catalysis.
122 mean pH 7.9 vs 10.9), lower alkalinity (mean titratable alkalinity 0.4 vs 1.4 mol H(+) kg(-1)), lower
124 y explain up to a quarter of the increase in titratable alkalinity within 1000 meters of the ocean su
125 tained through analysis of deletion mutants, titratable alleles of ribonucleotide reductase genes, an
126 tic, benzocaine, does not, suggesting that a titratable amine is required for high-affinity inhibitio
127 selectivity mechanisms postulate that (1) a titratable amino acid residue in the permeation pathway
128 s is the interactions between the charged or titratable amino acid residues (e.g., Glu, Lys, and His)
129 the four histidines protonated and if other titratable amino acid residues in lieu of the histidines
130 one must assign correct ionization states to titratable amino acid residues in protein channels.
131 est this hypothesis, the pK(a) values of the titratable amino acid residues in rhodopsin have been ca
133 wo redox-active tyrosines with N-containing, titratable amino acid side chains in their environments.
134 le to the sites of protonation, allowing all titratable amino acid side chains to be probed sequence
136 ds within the two extracellular loops to non-titratable amino acids had no effect on pH sensitivity.
139 ces with hydrogens, predicting pK values for titratable amino acids, assigning predefined partial cha
140 roximal to charged moieties, including ions, titratable amino acids, sulfates, phosphates, and nucleo
142 itoring and equipment, safer and more easily titratable anaesthetic agents, and possibly the practice
143 that DNA-PK's ability to repress HR is both titratable and entirely dependent on its enzymatic activ
144 The conservation of this arrangement of titratable and hydrophobic residues among ABC transporte
148 e protein, some SH groups become more easily titratable, and at pH 9.0 the PMP peak appeared around 3
150 ducible degradation system to achieve rapid, titratable, and reversible control of Polo-like kinase 4
151 as both the lysine and phosphate groups are titratable, and so calculations are given for several ch
152 t successful incorporation of the isosteric, titratable Arg analog, canavanine, into a neurotransmitt
154 Unlike all other amino acids, histidine is titratable at pH 6-7 carrying a positive charge below pH
155 both bound to the same subunit (cis), then a titratable burst of ATP hydrolysis is observed correspon
156 Substitution to arginine creates a channel titratable by external pH, suggesting that the side grou
158 not dependent on deprotonation of any of the titratable cationic groups in the peptide in the pH 4-10
161 with various promoters, we achieved precise, titratable control of heterologous gene expression in cy
162 s approach to achieve rapid, reversible, and titratable control of protein localization for eight dif
166 vitro using egg extracts, demonstrating that titratable cytoplasmic factors determine nuclear size to
169 Using immortalized human myoblasts with a titratable DUX4 transgene, we identify by mass spectrome
170 he authors generate a novel mouse model with titratable expression of DUX4, and show that it recapitu
171 s study, we engineered P. aeruginosa for the titratable expression of the biosynthetic aze gene clust
172 neering of synthetic utilization pathways as titratable expression systems and for metabolic engineer
174 var gene family, suggesting that a limiting titratable factor plays a role in var gene activation.
175 e families, suggesting that the var-specific titratable factor previously described is shared by all
177 tion and in vivo efficacy of a programmable, titratable, genetically engineered E. coli Nissle 1917 s
178 lation of AtMC9 activation involves multiple titratable glutamate and histidine residues across the t
180 due in the M1-H5 linker was mutated to a non-titratable glutamine, i.e. H116Q in GIRK1 and H120Q in G
181 on of [3H]-3 alpha-Diol showed that the same titratable group (pK = 7.50 +/- 0.30) was eliminated in
184 via deprotonation at C-5' proceeds with one titratable group displaying an apparent pK(a) value of a
185 Since only the Y55F mutant eliminated the titratable group in both the reduction and oxidation dir
186 By altering the protonation state of the titratable group in the tripeptides, we observe a notabl
187 D97N mutant, possibly the same as the second titratable group modulating the absorption spectrum.
188 of the cofactor redox potentials, and of the titratable group pK(a) values, in hydroxylamine oxidored
192 at C-5' follows a pH-rate profile having one titratable group with an apparent pK(a) value of approxi
194 ral titrations of BPR indicate that a second titratable group, in addition to the retinylidene Schiff
195 total of 100 ns, that the pKa values of the titratable groups are in good agreement with experimenta
196 iency at pH 9.0, and apparent pKa values for titratable groups at approximately 8.7 and 9.3 are revea
197 g to the calculated ionization states of its titratable groups at the user-specified pH; the output i
198 General conclusions about the role of these titratable groups in emission modulation have been drawn
199 First the pK(a) values of all the acidic titratable groups in HdeA are obtained and reveal a larg
201 dronium ions, but instead must interact with titratable groups that line the pore of the channel.
203 way by altering the spatial juxtaposition of titratable groups to regulate their activity in a spatio
204 nd MTA exhibits a pH-rate profile having two titratable groups with apparent pK(a) values of 1.2 +/-
205 , k(c), fits best to a model for two or more titratable groups with pK(a) of ca 5.6, suggesting a rol
206 , also exhibiting a pH-rate profile with two titratable groups with pK(a) values of approximately 0.8
212 and EIII act together to stabilize a single titratable H+ ion and behave nearly symmetrically in inf
213 res selection and screening markers that are titratable, have a high dynamic range, enable high-throu
216 rium differences to the presence of a second titratable histidine, His27, which may increase the prot
217 The standard enthalpy of ionization of six titratable histidines in horse metaquomyoglobin was dete
219 These constructs all exhibited unimodal titratable induction of gene expression, however, max in
220 that all three systems function and exhibit titratable induction, together covering a dynamic range
222 noviral-Cre or lentiviral-Cre vectors allows titratable initiation of pancreatic neoplasias that prog
223 that CH bond cleavage is not masked by other titratable kinetic steps belonging to the reductive half
224 s genome editing within cells and allows for titratable levels of editing efficiency and spatial patt
226 l-depleted donor bone marrow, which promotes titratable macrochimerism and a reshaping of the T cell
227 ase, and phenotype of sCAR-T cells in a dose-titratable manner in a Nalm-6 xenograft rodent model of
228 the late promoter in a sequence-specific and titratable manner, resulting in a delay in late gene exp
229 elength is blue-shifted by EGFR-binding in a titratable manner, up to 20 nm, with nanomolar detection
230 domain, these synthetic peptides function as titratable, modular, and potent transcriptional activato
232 stidine button' engineered in TnI produces a titratable molecular switch that 'senses' changes in the
233 reating antagonist-agonist pairs of EOM with titratable, naturally occurring myogenic signaling and g
234 NBD-lysophosphatidylethanolamine, having one titratable negative charge, was increased in the presenc
236 promise, the development of specific, easily titratable, parenteral agents has made intensive care un
238 environment, and the availability of readily titratable pharmacologic agents together stimulated the
240 e supporting the use of yohimbine as a safe, titratable pharmacological agent for translational alcoh
242 ncy of the enzyme and loss of one of the two titratable pK(a) values that govern the activity of the
244 lose kinase promoter is a tightly regulated, titratable promoter which will be useful for target vali
246 pH 6.5 and 8.5, indicating that there is no titratable protonatable group that influences significan
247 g of Pi and tungstate, a P(i) analog lacking titratable protons over the pH range of 5-11, and from t
248 ISPRi) enables programmable, reversible, and titratable repression of gene expression (knockdown) in
250 ately predicting the pK(a) value of a buried titratable residue, Asp-66, in the interior of the V66E
252 high pH, provided that the effects of nearby titratable residues are considered in the data analysis.
253 ndicative of a potential near -170 mV if the titratable residues are constituted of aspartates and gl
254 mology model to calculate the pKa of several titratable residues around the glutamate binding site to
256 lease involves ionization changes in several titratable residues associated with CD and EF loop appos
258 Although the surrounding solvent of several titratable residues changed from water to lipid in this
260 work, we computed the protonation states of titratable residues for this system and obtained values
265 pting the standard protonation state for all titratable residues leaves a large net charge on the sys
266 the protonation states at neutral bulk pH of titratable residues lining the lumen of the native Esche
267 ca exchange to determine the pK(a) values of titratable residues of a glycoside hydrolase (GH) family
269 e metal permeation pathway is lined with six titratable residues that can coordinate the positively c
270 he virtual pK(a) (i.e., the composite of all titratable residues that contribute to the LCC) is 5.8.
271 cial area, dielectric environment of the key titratable residues, and geometry of the residue disposi
272 ed by a cluster of evolutionarily conserved, titratable residues, at the cytoplasmic ends of TMs II,
273 ical studies, we identified several critical titratable residues, including two histidine residues (H
274 ase and alphaLP have the same number of acid-titratable residues, kinetic studies revealed that the h
275 haps the most significant finding is how key titratable residues, such as DFG-Asp, alphaC-Glu, and HR
276 resembles human ocular hypertension, having titratable, robust, and sustained IOPs caused by increas
277 veals conformational changes in Fc and three titratable salt bridges that confer pH-dependent binding
278 aline pH values; this can be attributed to a titratable shift (pKa = 7.8) in the slope of the urea de
279 calculate the pKa shifts for the ligands and titratable side chains of D-alanine:D-alanine ligase of
281 the effects of pH, the protonation states of titratable side chains were sampled by running constant-
284 he inactivation ball domain as a critical H+ titratable site mediating the pH effects on N-type inact
285 2) in the ball domain constitutes another H+ titratable site that mediates the pH effects in the more
286 by considering the protonation states of all titratable sites as well as the energy contributed at th
287 e binding data with respect to the number of titratable sites as well as the impact of each mutation
289 e photocycle is addressed by including as pH-titratable sites not only Glu204 and Glu194, residues ne
290 ile mutation of sites 1, 3, or 4 leave three titratable sites that are mostly filled with 3 Ca(2+) eq
291 n of site 2 leaves the protein with only two titratable sites, while mutation of sites 1, 3, or 4 lea
292 Fermentation parameters (pH, lactic acid and titratable sugar) were considered to be regulated during
294 Here, we have established a doxycycline-titratable system for genetic induction of permanent int
296 otential of safer, more specific, focal, and titratable treatment, with far-reaching clinical applica
300 dependence that is reversible and externally titratable, yet highly targetable and less invasive than