ライフサイエンスコーパス: to maintain

1 her promote or resolve inflammation in order to maintain a balanced inflammatory response.

2 an unfavourable outcome require less cooling to maintain a core temperature between 33 and 34 degrees

3 CsA continued to maintain a favorable safety profile.

4 tected from genotoxic and proteotoxic stress to maintain a healthy pool throughout life(1-3).

5 "small-molecule regime," which allows water to maintain a high hydrogen bond count at the expense of

6 Rats were trained to maintain a hind leg in a flexed position to avoid nox

7 We show that the piezo voltage used to maintain a null deflection provides a reliable measur

8 d to either receive antithrombin concentrate to maintain a plasmatic level 80-120% (treatment) or not

9 dicate that hippocampal inputs are necessary to maintain a precise cortical representation of space.

10 D) world is a complex task that requires one to maintain a proper sense of orientation relative to bo

11 th disrupted inner membranes that are unable to maintain a proton gradient, while expelling their nuc

12 ents, which compensate for head tilt changes to maintain a similar visual field relative to the horiz

13 by a 4-wk phase of weight maintenance or had to maintain a stable weight over the whole study period.

14 expansion, the principle of our approach is to maintain a zero amplitude harmonic cantilever deflect

15 gens, in turn, develop successful strategies to maintain access to bioavailable metal ions under cond

16 When the environment changes, vision adapts to maintain accurate perception.

17 ements that permit certain sequence variants to maintain activity.

18 Whether protrusive activity is required to maintain adhesion in confluent sheets of epithelial c

19 nvestigated the potential of amnion hydrogel to maintain ADSC functions, the synergistic effect of AM

20 that autophagy and Lkb1 work synergistically to maintain adult mouse homeostasis and survival.

21 an easy and effective preservation strategy to maintain aerobic metabolism, protect mitochondria, an

22 pithelial cells possess intrinsic mechanisms to maintain an appropriate cell density for normal tissu

23 e between g and working memory - the ability to maintain and control mental information, and that the

24 ological defects, called "Y-Junctions", form to maintain approximately constant cell spacing.

25 lity for the adhesive tip of the CshA fibril to maintain bacterial attachment that withstands shear f

26 facilitating colonization of naive habitats to maintaining bacterial community stability.

27 e speculate that it is critical for a system to maintain balance between its stochastic and determini

28 c role of these gammadelta T cell subsets is to maintain barrier integrity and prevent microorganisms

29 breadth), the benefits obtained and ability to maintain benefits across a variety of partners (fitne

30 ein quantities with the cell volume in order to maintain biomolecule concentrations and cell density.

31 coordinate or compete with their "neighbors" to maintain biosynthetic and bioenergetic demands while

32 oderate doses confer advantages, which serve to maintain bipolar disorder in the population.

33 ease from pancreatic beta-cells is essential to maintain blood glucose homeostasis.

34 Optimizing dose and schedule to maintain BR dose intensity may improve efficacy and t

35 B), a specialized neurovascular unit evolved to maintain brain homeostasis.

36 strong selection pressures for G. australis to maintain broad spectral sensitivity for the brightly

37 es had the deepest roots, which is necessary to maintain canopy during simulated dry seasons.

38 poxia during thermal stress were appropriate to maintain CDO(2) at normothermic, normoxic values.

39 l regulation of mRNA expression is necessary to maintain cell identity and cellular plasticity via th

40 ith c-MYC overexpression also required ABCE1 to maintain cell proliferation and translation.

41 opose that the energy harvested by PRs helps to maintain cell viability in dominant coastal photohete

42 Removing the constraints imposed by having to maintain cell viability might facilitate improved pro

43 the secretory pathway and must be retrieved to maintain cell viability.

44 f how bacteria control potassium homeostasis to maintain cell volume and osmotic potential.

45 ular reprogramming in germ cells is critical to maintaining cell fate and fertility.

46 fferent cellular compartments, are essential to maintain cellular homeostasis during development and

47 that phosphorylates a wide range of proteins to maintain cellular homeostasis.

48 ophoblasts followed by culture in TSC medium to maintain cellular proliferation.

49 xpensive metabolic process that is essential to maintain cellular respiratory capacity and requires t

50 an intracellular degradation pathway crucial to maintaining cellular homeostasis by clearing damaged

51 e duplication occurs once in each cell cycle to maintain centrosome number.

52 ivation, whereas phosphorylation serves only to maintain channel activity beyond termination of the P

53 To maintain clinical standards whilst ensuring patient s

54 y (PA) has been hypothesized to be effective to maintaining cognitive function and delay cognitive de

55 e insensitive, time-consuming, and difficult to maintain competency.

56 Pulse applications were chosen to maintain constant applied electrical energy (J) or to

57 trations without the addition of cosolvents, to maintain constant concentrations during the test, and

58 This pathway is sufficient to maintain continuous rod function and support cone pho

59 QS functions present a variety of abilities to maintain culturability during the transition to a VBN

60 e observed dynamics for all taxa were unable to maintain current community composition, highlighting

61 at suggest adaptation of placental transport to maintain delivery of critically needed FA.

62 polyubiquitination, and stabilizes ankyrin-G to maintain dendritic spine development.

63 n of allergen is needed for most individuals to maintain desensitization.

64 rabidopsis DNA methyltransferase, is crucial to maintain DNA methylation homeostasis to ensure genome

65 n turn, hosts develop novel immune receptors to maintain effector recognition and mount defences.

66 re focal points of the metabolic adjustments to maintain embryonic carbon/nitrogen homeostasis.

67 y flexibly recruit or reduce activity in A25 to maintain emotional equilibrium, a process that is dis

68 Tumor cells often exhibit augmented capacity to maintain endoplasmic reticulum (ER) homeostasis under

69 To maintain energy homeostasis during cold exposure, the

70 enteroendocrine tuft cells appear essential to maintain epithelial homeostasis following modificatio

71 Qualitative work investigated how to maintain equipoise.

72 in late larvae and adults, UNC-3 is required to maintain expression of MN-specific TFs.

73 ting in compensatory growth of the placentae to maintain fetal development.

74 relation to temperature can allow organisms to maintain fitness in response to increasing temperatur

75 directly regulates SlWUS expression domains to maintain floral stem-cell homeostasis.

76 CA family genes are synergistically required to maintain flower development.

77 Corti fluid are resorbed by supporting cells to maintain fluid homeostasis.

78 er wheat (Triticum aestivum L.) is essential to maintain food security for a large proportion of the

79 In addition, DNA replication is required to maintain full Pol II occupancy on viral DNA and to pr

80 Sacoglossan sea slugs are able to maintain functional chloroplasts inside their own cel

81 t can be tuned after their physical assembly to maintain functionality across diverse environments an

82 s is crucial for many cellular processes and to maintain general proteostasis.

83 romatin in altering its own mechanical state to maintain genome integrity in response to deformation.

84 the cell cycle regulates S phase progression to maintain genome integrity.

85 oposed that macroautophagy must be inhibited to maintain genome integrity.

86 3K27me2 in silencing euchromatic transposons to maintain genome stability and in modifying genetic re

87 To maintain genome stability, the SAC must be strong to

88 and how such events are normally suppressed to maintain genome stability.

89 culpting functions in multiple DDR processes to maintain genome stability.

90 repair pathway is essential for C. albicans to maintain genomic stability and survive in the host.

91 rror-free repair of DNA double-strand breaks to maintain genomic stability.

92 SP1 signals through Integrin alpha6beta1-Akt to maintain GSCs by an autocrine mechanism and M2 TAMs t

93 logical output of intestinal neural circuits to maintain gut homeostasis and health.

94 tive transcriptional elongation is essential to maintain H3K27ac abundance.

95 area substrates should be selected not only to maintain hatchling sex ratios, but also to minimize n

96 inimum recommended sleep duration for adults to maintain health [5] - including immune health - incre

97 The ability to maintain health, or recover to a healthy state after

98 r but can also equilibrate between the sites to maintain heme homeostasis.

99 r response in small retinal vessels in order to maintain hemodynamic regulation in the retina when ex

100 Alkalis eliminate the trap states, helping to maintain high current density.

101 ht rods, while genetically engineering cells to maintain high curvature reduced microcolony formation

102 ydrogenase)-like enzyme, Aifm2 oxidizes NADH to maintain high cytosolic NAD levels in supporting robu

103 inal increases in protein synthesis in order to maintain high proliferation rates.

104 the multiple biophysical properties required to maintain high rates of action potential firing and tr

105 ng and polarity due to -OH group is required to maintain high transfection.

106 les need to be recycled and refilled rapidly to maintain high-frequency synaptic transmission.

107 s conditionally ablated, T cells were unable to maintain higher expression of the cytoplasmic NF-kapp

108 dolutegravir-abacavir-lamivudine with regard to maintaining HIV-1 suppression.

109 requires tight control of the various inputs to maintain homeostasis and allow for proper responses t

110 ost-microbiota relationship that is required to maintain homeostasis and prevent disease.

111 biotic relationships have evolved as a means to maintain homeostasis where the role of the microbiota

112 e a diverse array of macromolecular machines to maintain homeostasis, allow for growth, and facilitat

113 ms that control endothelial barrier function to maintain homeostasis.

114 an discover how cells adapt to new molecules to maintain homeostasis.

115 ilitating competitive exclusion of pathogens to maintain human health.

116 3(+) regulatory T cells (Treg) are essential to maintain immune tolerance, as their loss leads to a f

117 e most primitive hematopoietic cell and also to maintain immune/hematopoietic homeostasis.

118 es, but understanding of how these integrate to maintain immunological homeostasis is incomplete.

119 cluding ER+ cells that have been challenging to maintain in culture.

120 ivated by flagellin to act as a "safety net" to maintain inflammasome activation under conditions of

121 Working memory (WM) is important to maintain information over short time periods to provi

122 Homeostatic systems combine an ability to maintain integrity over time with an incredible capac

123 ls interactions between IECs and macrophages to maintain intestinal barrier function.

124 IL-22 production in CD4(+) T cells and ILCs to maintain intestinal homeostasis.

125 transporter expression are dependent on GLS to maintain intracellular glutamate to prevent the amino

126 and a homeostatic mechanism, allowing cells to maintain invariant diffusion across a 20 degrees C te

127 one degrades NKA, resulting in the inability to maintain ion transport.

128 d, and requires ongoing type I IFN signaling to maintain it.

129 end performing MRF T(1) prior to DCE imaging to maintain its benefit for improving detection of both

130 The adult brain seems to rely on regular use to maintain its functional architecture.

131 performs its functions may guide strategies to maintain its health span and provide a permissive mil

132 requires balanced endocytosis and recycling to maintain its structural integrity and that impairment

133 r microbial ligand cycling may have occurred to maintain "just enough" iron in the ocean.

134 that this rescued detachment pathway is key to maintaining kinesin processivity under load.

135 tly reduces anti-inflammatory LXA4 secretion to maintain KSHV latency in infected cells.

136 ne/threonine protein kinase family is linked to maintaining latency.

137 rent life-history strategies, that could act to maintain life-history variation.

138 ows an optimal behaviour related to the need to maintain long-term average photosynthetic capacity (V

139 pression of basophil activation was required to maintain long-term clinical tolerance after peanut OI

140 sity to promote the persistent firing needed to maintain, manipulate, and store information without "

141 To maintain masking, TAK-003 recipients were administere

142 ation), defined as the need for vasopressors to maintain mean arterial pressure greater than or equal

143 the diverse strategies plants and algae use to maintain metal homeostasis.

144 that the method of MHM synthesis is crucial to maintaining MH properties.

145 This anchoring is critical to maintain microtubule organization by opposing kinesin

146 in EB1/Bim1 and recruits Bim1 to the midzone to maintain midzone length.

147 led the importance of landscape connectivity to maintain migration and gene flow between fragmented p

148 length represents a compensatory adaptation to maintain migration as reductions in body size have in

149 nisms, requiring ATP7 and COG, are necessary to maintain mitochondria functional integrity and locali

150 We propose that approaches that seek to maintain mitochondrial fitness, rather than target do

151 pregulates the mitochondrial stress response to maintain mitochondrial integrity.

152 ls, Slc7a5 import of amino acids is required to maintain mTOR activity.

153 ting functions, providing selective pressure to maintain multiple copies of 3B.

154 myogenesis and muscle mass, whereby it acts to maintain muscle mitochondrial function and limit auto

155 essary to seal the pulp chamber in an effort to maintain natural dentition and prevent pulpal infecti

156 r envelope (NE) undergoes dynamic remodeling to maintain NE integrity, a process involving the inner

157 e in concert or at different temporal scales to maintain network activity around a set-point value.

158 stant replacement, which is likely necessary to maintain network plasticity to accommodate growth and

159 r, our data indicate that NKCC1b is required to maintain neuronal activity-related solute homeostasis

160 aged mitochondria, is thought to be critical to maintain neuronal homeostasis.

161 anelles via selective autophagy is important to maintain neuronal homeostasis.

162 ment membrane receptor dystroglycan function to maintain niche cell wrapping, which is critical for n

163 n the GluN1 subunit of the NMDAR is required to maintain NMDARs at dendritic spine synapses and media

164 Thus, nodal spectrins are required to maintain nodal Na(+) channel clusters and the structu

165 ndent fluctuations in NS levels are required to maintain normal cell physiology and are dysregulated

166 compensated for by other app family members to maintain normal development.

167 eptide YY is required in the small intestine to maintain normal electrophysiology in the presence of

168 lar system exhibits strong circadian rhythms to maintain normal functioning.

169 R(I) that represents a compensatory response to maintain normal glucose tolerance but is impaired in

170 ponse to offset the defect in insulin action to maintain normal glucose tolerance.

171 other environmental challenges is paramount to maintain normal health, and individuals lacking or un

172 ecular meshwork's (TM) physiological role is to maintain normal intraocular pressure by regulating aq

173 ates atrial arrhythmogenicity, while helping to maintain normal levels of Ca(2+) transients and heart

174 We find that MFSD12 is required to maintain normal levels of cystine-the oxidized dimer

175 tify epigenetic regulators that are required to maintain normal nuclear shape in human breast epithel

176 at NPVF acts upstream of serotonin in the RN to maintain normal sleep levels.

177 variety of immune cells, which are critical to maintain normal tissue functions.

178 deling, where it regulates ESCRT disassembly to maintain nuclear envelope integrity and proper ER arc

179 c encounters with Ag occur frequently enough to maintain oligoclonal populations of inflationary CD8(

180 r affective reasons, such as the willingness to maintain one's moral self-image, but also by instrume

181 ere, we show that IL-2 signaling is required to maintain open chromatin at hundreds of gene regulator

182 hibit active nucleosome positioning required to maintain open transcription-initiation sites.

183 onditions, the cell volume must be regulated to maintain optimal neural function.

184 higher baseline LBP or sCD14 were less able to maintain or increase response speeds at higher inters

185 nsport and metabolic plasticity are required to maintain osmotic and protein homeostasis during remod

186 or plant nutrient, as fertilizer is critical to maintain P level for crop production and yield in mos

187 plore nurses' role(s) and their contribution to maintaining patient flow in acute hospitals through e

188 in the absence of relational work by nurses to maintain people's identity, establish caring connecti

189 cally relates to stamina; i.e., the capacity to maintain performance over long periods.

190 20) show that lysosomes fuse with phagosomes to maintain phagosomal membrane integrity as the fungal

191 w this holy trinity of risk factors interact to maintain physiological homeostasis in the brain and b

192 ovides plants with the metabolic flexibility to maintain physiological levels of acetate and a metabo

193 s to be augmented by additional mechanism(s) to maintain pigment levels in the face of high rates of

194 dling activity all reduce Ena/VASP's ability to maintain polarized network growth in the absence of C

195 ions for specific air pollutants and sectors to maintain pollutant concentrations below standards.

196 Our results highlight the need for cells to maintain poly(A)-RNA levels in balance with PABPs and

197 ned reinforcement learning agent can be used to maintain populations at target levels, and that model

198 We show that this domain contributes to maintaining processive replication through G4-forming

199 ivates IDO/kynurenine/AHR signaling in BMM s to maintain prolonged SOCS1 expression.

200 sosomal protease cathepsin D and is required to maintain proper cathepsin D levels in oligodendrocyte

201 tween peptidoglycan synthesis and hydrolysis to maintain proper cell morphology.

202 against cis-acting Arg(349) compels Arg(349) to maintain proper conformation of Walker A.

203 lts suggest LSD1 works in opposition to HCHC to maintain proper heterochromatin boundaries.

204 secretion, and energy production and serves to maintain protein homeostasis in various cellular comp

205 roteostasis collapse, the diminished ability to maintain protein homeostasis, has been established as

206 Molecular chaperones are known to maintain protein homeostasis.

207 process has evolved as a means for the cell to maintain proteostasis, by mitigating the risk of prot

208 ional co-activators YAP and TAZ are required to maintain PROX1 expression in LVs and LVVs in response

209 itant increase in the number of ions sampled to maintain quantitative accuracy.

210 ntially due to increased NAD(P)H utilization to maintain redox homeostasis.

211 restored HR and rescued the ability of cells to maintain RNF168 and ub-H2AX overexpression.

212 , our findings indicate that T7SS contribute to maintaining S. aureus membrane integrity and homeosta

213 helial cell-initiated signaling is necessary to maintain self-renewal of dental pulp stem cells.

214 t activate low levels of telomerase activity to maintain short telomeres.

215 y represent phenotypes that have the ability to maintain size and/or membrane ionic permeability unde

216 ry ion channel localization, and is required to maintain somatosensory function in vivo Interestingly

217 nd tetrapods), in which Pax6 would be needed to maintain specific entities of subpopulations of neuro

218 location and septal peptidoglycan remodeling to maintain spore development.

219 jection of HoxB8 progenitors also allowed us to maintain stable circulating HoxB8 neutrophil counts f

220 mRNAs undergo strong translational buffering to maintain stable protein expression levels in 2iL-ESCs

221 ses and could therefore serve as a reservoir to maintain steady-state levels of CXCL1 in infected tis

222 cal aggregation as a means of expanding MSCs to maintain stem cell functionality.

223 ures efficient Esg-dependent gene repression to maintain stemness and intestinal homeostasis.

224 em cells reside in and rely upon their niche to maintain stemness but must balance self-renewal with

225 on DAF-16/FOXO activation in vulval tissues to maintain stress resilience in the mother, suggesting

226 equires continuous remodeling of bone matrix to maintain structural integrity.

227 etermine if there is sufficient patient load to maintain such a service.

228 The energy needed to maintain suitable water quality, with associated emis

229 le (SV) endocytosis is coupled to exocytosis to maintain SV pool size and thus neurotransmitter relea

230 ire action potential-dependent communication to maintain synchrony.

231 both the presynaptic and postsynaptic sides to maintain target cell activity.

232 er injury on MRI require less active cooling to maintain target temperature during TH.

233 It has been observed that, AP helps to maintain temperature, moisture level and microbial an

234 etter recapitulate human disease, are easier to maintain than other primary cells, and are less expen

235 y to reduce p21(Cip1) protein as a mechanism to maintain the aggressive epidermal SCC phenotype.

236 lts altogether show that the DDR is required to maintain the balance proliferation differentiation an

237 ta and DNA ligase at the final ligation step to maintain the BER efficiency.

238 arious combinatorial CAR constructs in order to maintain the CD19 CAR T cell efficacy, but with IGK C

239 transport across the sarcoplasmic reticulum to maintain the charge balance of the transport sites an

240 er filtration remains one important approach to maintain the cleanliness of indoor air in hospitals.

241 atic changes in magnitude and relative order to maintain the delicate balance associated with equilib

242 face of terminals and locally reinserts them to maintain the diffusible surface pool.

243 s require sustained release of drug payloads to maintain the effective therapeutic level.

244 These analyses indicate that Cdk1 functions to maintain the epigenetic identity of ESCs.

245 ng channel, the Sec61 complex also functions to maintain the ER permeability barrier, preventing the

246 module of the ER translocase and is required to maintain the ER permeability barrier.

247 template carrying the wild-type repeat size to maintain the genetic architecture of the locus.

248 itates the processivity of RNA polymerase II to maintain the high expression of key genes (including

249 an outdoor cover of the prototype chamber is to maintain the high indoor temperature while the outdoo

250 und cellular organelle that generates energy to maintain the homeostasis of cells.

251 iota interacts with the host immune response to maintain the homeostasis.

252 osomes, and is subject to selection pressure to maintain the hyperrecombinogenic properties of these

253 e-based flow management is no longer tenable to maintain the integrity and functionality of aquatic e

254 Strategies to maintain the integrity of ongoing studies, including

255 Some virulence factors serve to maintain the integrity of the outer membrane, includi

256 purities and poisoning elements, yet is able to maintain the integrity of the substrate because of th

257 (LD) tethering protein, as a factor required to maintain the lipid saturation balance of cell membran

258 nation strategy, a containment strategy aims to maintain the maximum tolerable number of pathogens, e

259 We demonstrate that CBFbeta is essential to maintain the mesenchymal phenotype of triple-negative

260 operated at temperatures above 240 degrees C to maintain the metallic electrodes in a molten state.

261 with mitochondrial proteases and chaperones to maintain the mitochondrial proteome.

262 ylation-mediated SOCS1 induction is required to maintain the negative feedback control of macrophage

263 chronic kidney disease (CKD) have inability to maintain the normal levels of protein metabolism prod

264 I pathway requires MSH4 and MSH5 (MutSgamma) to maintain the obligate CO/chiasma and accounts for ~85

265 e, the methyl group repels interfacial water to maintain the planarity of the molecule, indicating th

266 We show that glycolysis is required to maintain the plasma membrane potential and that plasm

267 results demonstrate that TDP-43 is required to maintain the protective functions of astrocytes relev

268 Instead, passive ECM pre-strain serves to maintain the shape independent from actomyosin contra

269 d can be considered as a promising technique to maintain the shelf life, without drastically affectin

270 since sustained Btnl expression is required to maintain the signature TCR.Vgamma7(+) IEL phenotype,

271 mponent of the nuclear envelope, is critical to maintaining the NMJ in mice.

272 Swimmers were not prone to maintaining the thrust and speed along the trial wher

273 urgery and design work to enable burns teams to maintain their cognitive stamina, lower their workloa

274 " CD8+ T cells enhance cellular adhesiveness to maintain their cytotoxic potential.

275 r drop dispensing (index date), and they had to maintain their enrollment for at least 18 months ther

276 motion path theory predicts that humans tend to maintain their habitual motion path (HMP) during loco

277 phagy is extensively used by activated ILC2s to maintain their homeostasis and effector functions.

278 irus disease 2019 research while endeavoring to maintain their preexisting agenda.

279 critical metabolic pathway in opposing ways to maintain their preferred epigenetic state.

280 tilage niche, allowing both cell populations to maintain their stem cell features and improve their i

281 entials to distant synaptic regions but also to maintain their timing.

282 treatment with immunosuppressive medications to maintain their transplant status.

283 We find that the key to maintain their warfarin sensitivity is to stabilize t

284 balancing selection likely contributes more to maintaining this mutation than does introgression.

285 marker of high biological fitness, is costly to maintain throughout a lifetime and may cause higher o

286 Our modeling demonstrates that to maintain timing, the underlying channel properties of

287 d light on this process and how it functions to maintain tissue homeostasis, tissue repair and organi

288 ath/survival balance is an important feature to maintain tissue homeostasis.

289 respond to neuron-derived signals necessary to maintain tissue integrity.

290 -tRNA at the ribosomal A site is fundamental to maintaining translational fidelity.

291 on, indicating that alpha3beta1 is essential to maintain tumor growth.

292 e S*, transporter abundance can be regulated to maintain uptake rates as demanded by maximal growth r

293 nctions (NVJs) cooperate with lipid droplets to maintain viability and enhance NPC formation in assem

294 RAD52 NTD that disrupt these activities fail to maintain viability of BRCA-deficient cells.

295 l death (RCD) when homeostatic programs fail to maintain viability.

296 mbling peptide gel (SPG-178) and its ability to maintain visibility during trabeculectomy surgery.

297 Anti-VEGF agents are efficient treatment to maintain visual acuity in residual/recurrent DME afte

298 he water vapor are the only sources of water to maintain water balance and prevent desiccation.

299 oning nutrient flux between muscle and liver to maintain whole-body lipid and glucose homeostasis.

300 red for telomerase to be active in vitro and to maintain yeast telomeres in vivo, whereas the DeltaCE