ライフサイエンスコーパス: topology

1 to novel RNA motifs (described by tree graph topologies).

2 G-strand and T-strand ssDNA to regulate DNA topology.

3 on of cortical regions based on the vascular topology.

4 nsmembrane domain that retained its membrane topology.

5 states that appear due to the change in band topology.

6 n studying the rich physics related to their topology.

7 h encapsulates lipid complexity and cellular topology.

8 e will produce dramatic effect on the entire topology.

9 n-like orbits associated with the underlying topology.

10 uitin chains differing greatly in length and topology.

11 and builds a network graph based on the data topology.

12 onformational space and generate native-like topology.

13 ived from the interplay between symmetry and topology.

14 these algorithms are based on the network's topology.

15 ings extend our understanding of SCN circuit topology.

16 y including network complexity, symmetry and topology.

17 ctures as a superior mechanical metamaterial topology.

18 the frustrated lattice geometry and quantum topology.

19 ng two pai-electrons in an orbital of Mobius topology.

20 at the confluence of strong correlation and topology.

21 cs and the statistical properties of network topology.

22 ligands, each of which exhibits the deduced topology.

23 four-helix bundle including a pierced lasso topology.

24 olved with a means to manipulate its complex topology.

25 id-crystalline phases, however, of different topology.

26 stigate the effect of familiarity on network topology.

27 eration of 10 nets with different underlying topologies.

28 gnificantly alter the observed hydrogen-bond topologies.

29 rom a sample of ranked or unranked gene tree topologies.

30 works with tetragonal, hexagonal, and kagome topologies.

31 s, membrane proteins, or proteins of complex topologies.

32 or a variety of protein complexes of varying topologies.

33 Topology, a mathematical concept, has recently become a

34 ing supersite properties, dynamics, variable topologies, accessory helices, and malleability and abet

35 to metal-organic frameworks with the UiO-66 topology, achieved by attaching phosphonic acid to the 1

36 ethod, and evaluated support for alternative topologies across gene trees.

37 The knot topology affects the chemical properties of the strand:

38 g evidence links genetic lesions with genome topology alterations and aberrant gene activation.

39 loch bands that challenge our very notion of topology: Although answering to the most basic definitio

40 hydrogen bonding and by an electron density topology analysis that identifies characteristic feature

41 ue of their crystallinity, diverse framework topologies and accessible pore systems.

42 can be observed for two different framework topologies and for Na-exchanged (i.e., nonacidic) zeolit

43 The rich pattern of sister-chromatid topologies and our scsHi-C technology will make it possi

44 al cellular examples and discuss how layered topologies and self-regulation may impact key biological

45 uced by the interaction between polarization topologies and the radially symmetric dichroic elements

46 ay for the synthesis of other molecular knot topologies and to woven polymer materials.

47 angstrom, revealing a unique 7-TM structural topology and an intermediate adduct of finasteride and N

48 d its homolog MRAP1 have an unusual membrane topology and are the only known eukaryotic proteins that

49 Here we investigate how structure (network topology and body-size structure) and behaviour (foragin

50 eement with current cryo-electron microscopy topology and consistent with long-thought residue-to-res

51 thalaldehyde, which adopts desymmetrized hcb topology and consists of a staggered AB stacking structu

52 amine N-methyltransferase) has an N-out C-in topology and contains four transmembrane domains, with t

53 he quantum-level interplay between geometry, topology and correlation is at the forefront of fundamen

54 detail of medin pores with the CNpNC barrel topology and diameters comparable to values estimated fr

55 d polybasic motif that dictates the membrane topology and dimerization of MRAP1 does not control the

56 ithm can infer more accurate Boolean network topology and dynamics from short and noisy time series d

57 ch is able to infer accurate Boolean network topology and dynamics from short and noisy time series d

58 tanding of the coupling relationship between topology and dynamics.

59 pts an unreported 2-fold interpenetrated acs topology and exhibits reversible dynamic behavior, switc

60 We dissect key features, such as the network topology and fibre composition.

61 ontrol strategies for the leading edge shock topology and flow structures in supersonic flows.

62 open avenues for the field of non-Hermitian topology and for manipulating waves in unprecedented fas

63 technique for integrating structural network topology and functional activity to predict the influenc

64 the expressed genes, and shows a scale-free topology and functional modularity like a real-world net

65 New research reveals that the topology and geometry of cells in a tissue predicts the

66 e present a framework to utilize the network topology and identify interacting and non-interacting dr

67 , predict causal regulations, assess network topology and identify key regulators.

68 tigate chromatin marks, manipulate chromatin topology and induce epigenetic modifications at multiple

69 quantum anomalous Hall (QAH) effect combines topology and magnetism to produce precisely quantized Ha

70 s of nanoribbons should have unusual bonding topology and metallicity.

71 trong similarities between the Fermi surface topology and quasiparticle band structure of hole- and e

72 e two types of peptidomes are decoded by the topology and rates of kinetic proofreading signaling ste

73 tool that infers Boolean rules based on the topology and semantics of molecular interaction maps bui

74 for inferred Boolean models according to the topology and the annotations of the starting molecular i

75 tering the variance of the dispersal network topology and the patterns of ecological connectivity.

76 ect analyses that are robust to variation in topology and timecourse of neural responses.

77 ntermingling due to cohesin loss affects the topology and transcriptional bursting frequencies of gen

78 duces its power efficiency, due to imperfect topology and transistors.

79 driven approach to other building blocks and topologies, and broadens the family and scope of COFs.

80 xcellent electronic conductivity, designable topologies, and defined catalytic/redox-active sites), w

81 h chemical stability, diverse structures and topologies, and interesting properties and functions.

82 interaction network using multilayer network topology, and analyzed survival function of the signific

83 Allostery, topology, and building block stoichiometry all play impo

84 dding light onto the connectivity, geometry, topology, and dynamics of bonding.

85 characteristic flexibility, defined chemical topology, and length scale of these nanosheets set a cle

86 including APOL1's subcellular localization, topology, and whether the damage is related to trypanoly

87 stem in the human brain and investigated the topology approximation of the VMI network to the Allen H

88 res confirm the family's extremely rare dual topology architecture and reveal a cleft between two hel

89 Two novel donor-acceptor cruciform topologies are efficiently synthesized by site-selective

90 roteins are membrane-anchored proteins whose topologies are important for their functions.

91 The key ingredients for topology are certain symmetries, the inert pair effect o

92 the reduced congener with concomitant Huckel topology are the important highlights.

93 Geometry and topology are the main factors that determine the functio

94 f which gave us the idea of foldable network topologies, as the laf-net can fold into a 2D form while

95 el annotation source, sequence-dependent DNA topology, as a prioritization metric for fine-mapping.

96 e rate of enriched gene sets, (ii) a network topology assessment, (iii) ChIP-Seq evidence and (iv) th

97 res of network circuitry can identify kinase topologies associated with both phenotypes and genotypes

98 ification of hitherto unknown kinase network topologies associated with drug-resistant phenotypes or

99 port to the main flow and it causes the flow topology at the leading edge to become non-symmetric des

100 structure to predict corresponding tertiary topologies, (b) RAG Builder: builds three-dimensional at

101 We employ an algebraic topology-based machine learning model to quantitatively

102 e similarity of cortico-subcortical networks topologies between humans and nonhuman primate species i

103 aluate relationships, constrained by network topology, between gene sets related to different phenoty

104 Despite their differing topologies, both proteins have a similar distribution of

105 -Th-1 shows a UiO-66-type structure with fcu topology built on a Th(6) secondary building unit and a

106 Top2 alters DNA topology by making a double-strand break (DSB) in DNA an

107 ng juxtaposed helices and might modulate DNA topology by plectoneme stabilization and local compactio

108 ol cells as networks and analyze the network topology by state-of-the-art methods.

109 egmental size of polymer chains with varying topology by using the revisited thermal diffusion predic

110 nsional (2D) materials and complex molecular topologies calls for a robust experimental system for si

111 Such topologies can be potentially involved in the energy tra

112 Hence, we find that DNA topology can shape non-CG DNA methylation across the gen

113 Membrane topology changes such as poration, stalk formation, and

114 During the contraction, the skin topology changes, affecting a subpopulation of mechanose

115 ic multipoles that depend on particle shape, topology, chirality, boundary conditions and induced top

116 y bands and Fermi surfaces, via symmetry and topology, classifying topological materials within a sin

117 orming to complex shapes and parametric meta-topology control.

118 counterparts and introduces the potential of topology-control over viscoelastic flow.

119 as increased our understanding of how genome topology controls RAG endonuclease-mediated assembly of

120 This 7(4) knot topology corresponds to that of an endless knot, which i

121 Because of their topology, cyclic polymers exhibit a unique set of proper

122 A molecular clock based on our BI topology dates diversification of Mollusca to ~546 MYA (

123 across manipulations of synaptic weights and topologies, demonstrating the robustness of this regime

124 inescent even in the solid state and exhibit topology-dependent pai transmission and exciton migratio

125 s arrange to form an emergent meshwork whose topology dictates the mechanical properties of individua

126 l materials and the interconnected nature of topology, dimensionality, and symmetry in electronic sys

127 y have different intrinsic dimensions, local topology discovers singular regions in data even when no

128 ext] case and these differences between flow topology distributions in Rayleigh-Benard convection in

129 Then, the exotic polar topologies (e.g., domain walls, closure domains, polar v

130 retical metabolite database for a TPP of any topology (e.g., branched, multicyclic, etc.).

131 gy is applicable to templates with different topologies, enables designed synthesis of frameworks tha

132 -organic framework (MOF),with underlying fcu topology, encompassing the [Zr(6)(mu(3)-O)(4)(mu(3)-OH)(

133 into hexagonal channels of MIL-88 type (acs topology) endows materials with high tunability in gas s

134 n, manipulation of anisotropy, interface and topology engineering.

135 making it difficult to investigate enhancer topologies, especially in uncharacterized cell types.

136 a striking interplay of dynamics and network topology, excitations often establish a directional pref

137 We find that simulations run on the same topology exhibit sustained asynchronous activity under c

138 a magnetic system in which non-trivial band topology favours long-range order of orbital angular mom

139 nts of the velocity gradient tensor and flow topologies for Rayleigh-Benard convection of Newtonian f

140 ity topoisomerase in animals that can change topology for both DNA and RNA, and facilitate transcript

141 le machine learning model, to predict genome topology for cell types which lack long-range contact ma

142 llustrate the requirement of this regulatory topology for the precise timing of gene activation.

143 ression and infer the divergent phylogenetic topology for the white oak clade.

144 mino acid sactionine macrocycles, an unusual topology for this compound family.

145 s incorporating flexible chains; the network topology freezing temperature decreases with increasing

146 modules: (a) RAG Sampler: samples tree graph topologies from an RNA secondary structure to predict co

147 gorithms that can reconstruct kinase network topologies from these phosphoproteomics data.

148 Studies of the topology, functioning, and regulation of metabolic syste

149 trate that a carefully chosen combination of topology, geometry, and base material results in superio

150 each kinetoplast is dictated by its network topology, giving it a unique shape, which undergoes smal

151 Here we report the topology guided synthesis of an imine-bonded (C=N) duall

152 efficient exciton displacement, appropriate topology-guided assembly is required to fully realize th

153 technique to membrane proteins of arbitrary topology has remained in the lack of additional experime

154 y frustrated lattices, often with nontrivial topology if combined with spin-orbit coupling.

155 Achieving precise nanopore topologies in graphene using top-down lithographic appro

156 ep resistance achieved by control over chain topology in block vitrimers can be used to tune viscoela

157 vidence on the roles of DNA sequence and DNA topology in controlling R-loop formation and stability.

158 antitative insights imply a role of meshwork topology in laminopathies.

159 980, the extensive utilization of the cyclic topology in nature highlights the vital role that a cycl

160 Finally, a brief outlook on the impact of topology in other areas of chemistry is provided at the

161 results show substantial changes in network topology in response to the familiar (context).

162 hted different conformations of native APOL1 topology in serum (HDL particles) and at the podocyte su

163 APOL1 topology in serum (HDL particles) and in kidney podocyte

164 resolved in our structures, we determine its topology in the replisome by cross-linking mass spectrom

165 We find a rich variety of phase diagram topologies, including multiple critical points, triple p

166 of the flow and the volume fraction of nodal topologies increases in the vicinity of the active hot a

167 y history, even in cases with well-supported topologies inferred from genome-scale data.

168 iral genome and subgenomes adopt alternative topologies inside cells and engage in different interact

169 he formation of a ZMOF with a sodalite (sod) topology instead of a non-porous diamondoid (dia) topolo

170 t of native DNA is fixed, one can modify the topology instead to encode information.

171 tion, in terms of location, parcellation and topology (internal and external), is very similar to tha

172 Applied topology is a promising tool to discover invariant struc

173 s shows that the resultant phylogenetic tree topology is scale-invariant due to a singularity arising

174 inoazetidine-2-carboxylic acid, an 8-helical topology is shown to dominate for sequences up to n = 7.

175 xagons and triangles can combine to a new 3D topology laf, a model of which gave us the idea of folda

176 This new approach to charting thylakoid topology lays the foundation for dissecting photosynthet

177 t D00 is a unique Big domain with a specific topology likely found in a broad range of other inverse

178 n this study, we demonstrate the concept of "topology-matching design" for virus inhibitors.

179 ynthetic observations suggest that spherical topologies may be more stable than wheel-like clusters,

180 The fractal topology minimises fluorescence crosstalk and allows qua

181 In this work, we demonstrate the band topology modification via a weak magnetic field in a fer

182 Regardless of their topologies, non-B DNA structures exhibited impaired bind

183 enerations, yet neither the extended network topology nor its conservation is well established.

184 erminal part of Opi3 was consistent with the topology obtained by the substituted cysteine accessibil

185 studies and open-source code for diagnosing topologies of magnetic materials.

186 We have applied net-clipping to predict the topologies of MOFs containing zigzag ligands.

187 However, three-dimensional topologies of proteins change more slowly than sequences

188 The chemical structures and topologies of the crosslinks in supramolecular networks

189 resetting of the enzyme, for a net change of topology of +1 turn per cycle.

190 A network topology of 20 factors involved in renal MV rarefaction

191 e difficult inverse problem of inferring the topology of an unknown network from given time-dependent

192 Low pH did not detectably alter the gross topology of APOL1, as determined by antibody accessibili

193 educed genetic constraints on the structural topology of association cortex.

194 Taking advantage of the self-similar topology of Cayley tree, we use only 16 DNA strands to c

195 ns show that on the structured surfaces with topology of closed-loop nanowalls/nanochannels, the wate

196 es would allow these motors to couple to the topology of DNA when DNA is entwined with the braided co

197 We suggest that the native topology of DPO4 leads to a trade-off between fast, stab

198 into the algorithm of MTQC to determine the topology of each magnetic material.

199 archaeal host cell fundamentally altered the topology of genes in relation to bioenergetic membranes.

200 develop a method that incorporates both the topology of interactions and node attributes to extract

201 graph computational paradigm to analyze the topology of junction copy number (JCN) across 2,778 tumo

202 al phosphoproteomics method to elucidate the topology of kinase-signaling networks in mammalian cells

203 tructures a reality requires controlling the topology of kirigami to achieve connectivity and rigidit

204 We also analyzed the topology of low-resolution XWnt8/Fzd5 complex particles,

205 rs some similarities to the alpha/beta/alpha topology of members of the GDSL-like lipase/acylhydrolas

206 n we propose a new approach for deducing the topology of metal-organic frameworks (MOFs) assembled fr

207 Here we show that the topology of mPRbeta is similar to adiponectin receptors

208 The unique topology of MUL1 enables it to "sense" mitochondrial str

209 The membrane topology of Opi3 (and its human counterpart, phosphatidy

210 tch pathways remodel the secondary structure topology of proteins in response to the cellular environ

211 op and a tail-to study both the geometry and topology of proteins with closed loops e.g. lassos.

212 We show that the special topology of reaction spaces, with central hub molecules

213 quid droplets are the most commonly observed topology of RNA-protein condensates in experiments and s

214 By computing the local topology of small regions around each data point, we are

215 It is hard to manipulate the band structure topology of specific Weyl materials.

216 use their existence can be attributed to the topology of the closed-loop nanowalls/nanochannels.

217 ssection reveals the mode of association and topology of the complex, casts light on the recruitment

218 ars to largely preserve the basic structural topology of the cubane molecular precursor and exhibits

219 visualized within the context of the global topology of the data set.

220 The particular topology of the delaminated nanosheets, with quite dista

221 The unusual topology of the FlhB/SctU helices creates a loop wrapped

222 By permuting the topology of the four helices within FRB, we have created

223 applied to the graph to explore the overall topology of the graph and to predict the phenotype/clini

224 A comparison of the membrane topology of the HIV-1 MA, using the surface-mapping meth

225 on membrane insertion, predicting a possible topology of the membrane-inserted toxin in the different

226 Globally, it redefines the chromatin topology of the myeloid genome toward a more condensed c

227 vide expressions that hold regardless of the topology of the network connecting the intermediate stat

228 The topology of the network graph reflects established biolo

229 heir local connections and, accordingly, the topology of the network of interactions to respond to ch

230 ther the drug-induced gene expression or the topology of the networks used to model gene regulation p

231 The matrix topology of the sensor together with biofunctionalizatio

232 second reverses the typical outward-directed topology of the sheath electric field into a focusing co

233 yote origins is based on assertions that the topology of the tree of life depends on the taxa include

234 Here, we report the molecular topology of the UAF complex, describe new structural and

235 y reported the heat capacity of the sodalite topology of the zinc 2-methylimidazolate framework (ZIF-

236 f tetanurans remain contested, including the topology of their deep phylogenetic divergences (among M

237 The evolutive topology of these polar textures is driven by the (re)co

238 s, enable the calculation of metrics for the topology of trait coordination and the importance of giv

239 Analysis of the topology of transcriptional regulatory networks (TRNs) i

240 s interesting latent cognitive dynamics, the topology of which can be contrasted with several aspects

241 f the TRAV1-2(+) and TRAV36(+) TCRs' docking topologies on MR1.

242 ly, we investigated the influence of circuit topology on ratio-sensing and found that incorporating n

243 striking convergent evolution, with a unique topology, on a V-shaped bacterial GEF fold shared with o

244 gh answering to the most basic definition of topology, one can trivialize these bands through the add

245 noscale using a proposed method coined "Nano-Topology Optimization".

246 We adapted multiscale topology optimization, a mesh parametrization-based algo

247 er sequences, rather than either their exact topology or a particular chromatin architecture, is the

248 reation of non-trivial spin angular momentum topology pertains to cosmological structure creation and

249 rrelation at the level of chemical linkages, topology, pore size and functionality is needed to unloc

250 ferase, expressed in yeast) was addressed by topology prediction algorithms and by the substituted cy

251 We find that network topology predominantly determines the accuracy of ProTIN

252 mbodying both a structural motif and surface topology previously considered on the extreme limits of

253 These results demonstrate that topology provides a novel approach for characterizing ne

254 that are uniquely enabled by low-dimensional topology, quantum confinement and interfaces.

255 on microscopy, we investigate how chromosome topology relates to transcriptional activity of clustere

256 d small-world networks and find that network topology remains a key determinant of pricing and effici

257 nd strength limits of any isotropic cellular topology, respectively.

258 ccordingly, it has been found that the focal topologies S1 and S4 remain predominant in the bulk regi

259 r cent of the 130 topological materials have topologies sensitive to interactions, and the others hav

260 which Tet1 and Tet2 bind, at sites showing a topology similar to that of 5hmC sites.

261 al features, which include three-dimensional topologies such as Mobius, ribbon strips and knots.

262 The overall structural architecture and topology suggest the molecular mechanisms of nucleic aci

263 This phylogenetic topology supports the idea that the radiodont and megach

264 and synthesis of molecular cages with novel topologies targeting a broad range of applications.

265 lline porous covalent organic frameworks via topology-templated polymerization.

266 l imine-linked COF with a voided square grid topology, termed COF-432.

267 om the human telomere can adopt six distinct topologies that are inter-convertible under physiologica

268 ncreased valencies, promiscuous binding, and topologies that enable multivalent interactions) support

269 rogress made in synthesizing COFs of diverse topologies, the synthesis methods are often tedious and

270 specificity extends to both size and spatial topologies, thereby rivaling the synaptic specificity of

271 ology, the manifestation of their nontrivial topology through single skyrmions and ordered and disord

272 essure can cause proteins with local contact topologies to evolve cotranslational folding.

273 the low-spin state by changing the plaquette topology to an open chain.

274 ucture of Ste2 bears similarities in overall topology to class A GPCRs, but the transmembrane helix H

275 the importance of this particular regulatory topology to control Hoxd gene transcription in time and

276 aryotic topoisomerase 1 (TOP1) regulates DNA topology to ensure efficient DNA replication and transcr

277 ces in using molecular design and control of topology to showcase how a deep understanding of structu

278 rk, we present a unifying framework based on topology to understand non-reciprocity and directional a

279 mputes the Probabilities of RANked gene tree topologies under the multispecies coalescent.

280 to interactions, and the others have stable topologies under varying interactions. We provide a mate

281 ogy instead of a non-porous diamondoid (dia) topology under analogous synthetic conditions.

282 ill support long-term investigations of trap topologies unique to microgravity(4,5), atom-laser sourc

283 bly, sequence was shown to influence network topology upon cross-linking, as evidenced by sequence-de

284 cyclic bis[2]catenane with "infinity"-shaped topology via a 14-component self-assembly.

285 into, respectively, an angular and a linear topology via an unsaturated six-membered ring.

286 The effect of the overall topology was examined using several deletion variants.

287 Coanda effect, causing a non-symmetric flow topology, was observed and analyzed for reduced injectio

288 h a new method to visualize membrane surface topology, we map the molecular landscapes of thylakoid m

289 By examining their contribution to genome topology, we show that TEs can contribute to regulatory

290 s, fossil diagnoses should consider multiple topologies when phylogenetic resolution or clear apomorp

291 imeric G-quadruplexes towards (3+1) hybrid-2 topology, which became more pronounced as further G-quad

292 m earlier than the structure with the S-bend topology, which is in accord with Ostwald's rule rationa

293 or strand structure intrinsically determines topology, which means that only one type of knot is usua

294 Their topology, which originates in their chiral domain wall w

295 stablished that they exhibit scale-invariant topology, which quantifies the fact that their branching

296 essential role in determining the structural topology, which restricts RNA local and global folds, es

297 also increases the probability of finding S3 topologies with large negative magnitudes of Q and R.

298 tion in TRNs and the organization of the TRN topology with FFLs as building blocks.

299 Although predicted to share similar membrane topology with other large-pore forming proteins such as

300 alysis, supports a four transmembrane domain topology, with variants in transmembrane domains exhibit