ライフサイエンスコーパス: trans-activation

1 disengagement and, thereby, ligand-dependent trans activation.

2 acts with Runx2 and represses Runx2-mediated trans-activation.

3 in kinetin riboside as an inhibitor of CCND2 trans-activation.

4 ndent TEA domain transcription factor (TEAD) trans-activation.

5 heir abilities to enter HeLa cells and block trans-activation.

6 the COOH-terminal 98 amino acids function in trans-activation.

7 gative TIRAP blocked Rac1V12-induced HIV-LTR trans-activation.

8 e or no capacity for additive or synergistic trans-activation.

9 c1N17) partially blocked LPS-induced HIV-LTR trans-activation.

10 STAT3 and HDAC7 and modulate STAT3-mediated trans-activation.

11 verexpression will counteract Stat3-mediated trans-activation.

12 play important roles in the regulation of AR trans-activation.

13 ly(QA) domain acquired a significant role in trans-activation.

14 of the AOP2 promoter reduced LEDGF-dependent trans-activation.

15 a in mediating redox-sensitive iNOS promoter trans-activation.

16 erved regions of ZIC3 that are necessary for trans-activation.

17 ring of the two kinase domains, facilitating trans-activation.

18 ivity and for Hdac7- and HIF-1alpha-mediated trans-activation.

19 in enhanced Sp1-DNA binding activity and Sp1 trans-activation.

20 or-kappaB (NF-kappaB) resulting in HIV-1 LTR trans-activation.

21 h AR protein expression and R1881-induced AR trans-activation.

22 portant for interfering with Notch1-mediated trans-activation.

23 ent of effects on mineralocorticoid receptor trans-activation.

24 An IE62 TAD-ICP4 chimeric protein exhibited trans-activation ability (10.2-fold), indicating that th

25 We show that the trans-activation ability of Tat at the long terminal rep

26 he SRT were replaced with Ala, Leu, and Gly, trans-activation activities of the modified IE62 protein

27 matory mediator production but has lower GRE trans-activation activities than traditional steroids.

28 R) ligands that have high repression but low trans-activation activities.

29 Furthermore, PML4 facilitates GATA-1 trans-activation activity in an interaction-dependent ma

30 In addition, curcumin reduced the trans-activation activity of Egr-1 by suppressing egr-1

31 gene expression of EGFR through reducing the trans-activation activity of Egr-1.

32 Although bICP0 inhibits the trans-activation activity of IRF7, IRF7 protein levels a

33 n ERalpha mutants with significantly altered trans-activation activity toward E(2) in yeast cells.

34 SRT of equine herpesvirus 1 (EHV-1) IEP, its trans-activation activity was completely restored.

35 lin-dependent kinases (cdks) increases RUNX1 trans-activation activity without perturbing p300 intera

36 gonucleotide exhibited partial inhibition of trans-activation activity, but this was correlated with

37 utants of any nuclear receptors with altered trans-activation activity, which may greatly facilitate

38 eceptor alpha (ERalpha) mutants with altered trans-activation activity.

39 n erythroid differention by enhancing GATA-1 trans-activation activity.

40 d TLR9 in HIV-long terminal repeat (HIV-LTR) trans-activation and assessed whether TLR4 synergized wi

41 tion of NF-kappaB, as evidenced by NF-kappaB trans-activation and by p65 RelA and p50 NF-kappaB1 bind

42 loproteinase 9 (MMP9) promoter to induce its trans-activation and cell invasion.

43 first, a dileucine motif, is dispensable for trans-activation and cis-inhibition despite the endocyti

44 hibit cadmium inducibility also suppress the trans-activation and DNA binding activities of Nrf2, and

45 Both Stat3 and Stat5 mediate trans-activation and epigenetic remodeling of IL10 throu

46 in bacterial Ag- and CpG DNA-induced HIV-LTR trans-activation and HIV replication.

47 g-induced HIV-long terminal repeat (HIV-LTR) trans-activation and HIV-1 replication, and that LPS-ind

48 ti-apoptotic function of p53 is dependent on trans-activation and is linked to cell cycle arrest.

49 n-derived neurotrophic factor-responsive CRE trans-activation and neurotrophin protection against apo

50 hanges in hypoxia/reoxygenation stimulate AR trans-activation and sensitization.

51 WAF1) through protein stabilization and mRNA trans-activation and stabilization, respectively.

52 n with ethylidene glucose, or by transporter trans-activation and therefore was probably due to subst

53 in that has been shown to modulate HIV-1 Tat trans-activation and to repress transcription of some ce

54 The AR conveys both trans-activation and trans-repression functions, which t

55 kappaBalpha degradation as well as NF-kappaB trans-activation and transformation of NIH3T3 cells.

56 d p50 NF-kappa B1 binding to DNA, NF-kappa B trans-activation, and I kappa B degradation.

57 inducible nuclear translocation and Hsp gene trans-activation, and in the protection of mouse cells f

58 ime that activation of Rac1 leads to HIV-LTR trans-activation, and this is mediated through TIRAP.

59 Trans-activation (approximately 21-fold) of GAL4-CREB fu

60 ed further that Sp2 DNA-binding activity and trans-activation are each negatively regulated in mammal

61 r, we show that Sp2 DNA binding activity and trans-activation are negatively regulated in mammalian c

62 Because the MutH trans activation assay used in these previous studies wa

63 To address this question, a new cell-based trans-activation assay system suitable for ZIC proteins

64 A trans-activation assay using Hsp27 promoter revealed tha

65 MYC2 dynamically binds >1,300 promoters and trans-activation assays show that MYC2 activates these p

66 Furthermore, trans-activation assays show that the expression of SND1

67 recipitation-quantitative PCR and protoplast trans-activation assays were used to show that MtRRB3 ca

68 In FXR trans-activation assays, both the endogenous FXR agonist

69 three DR1 response elements as identified by trans-activation assays.

70 1) and 10 kcal/mol (dimer 2), with a cis to trans activation barrier of 20 kcal/mol.

71 act with TLR2 but had no effect on HIV-1 LTR trans-activation because of its inability to activate th

72 2000 to +73) restrained C/EBP alpha-mediated trans-activation, because mutation of each single GRU el

73 in steric block inhibition of Tat-dependent trans-activation both in vitro and in cells is governed

74 was necessary for inhibiting Notch1-mediated trans-activation but not apoptosis.

75 n with SRCs and abolished RORgammat-mediated trans-activation but not its ability to inhibit transcri

76 methasone and was active in potentiating the trans-activation, but not the trans-repression, properti

77 y promoter sequences that were necessary for trans activation by C/EBP-alpha.

78 ependent intracellular inhibition of Tat-TAR trans activation by the anti-TAR 3'-FAM 12-residue 7xOMe

79 both TFB promoters are required for maximal trans activation by the PGC-1 family coactivators, PGC-1

80 is module was confirmed with the blockade of trans-activation by a dominant negative Stat3.

81 C/EBPalpha-dependent trans-activation by AR also overrode suppression of AREs

82 lanine, suggesting that stimulation of RUNX1 trans-activation by cdk-mediated reduction in HDAC inter

83 es reduced trichostatin A responsiveness and trans-activation by histone acetyltransferases.

84 vation of the Stat3 motif completely ablates trans-activation by IFN-alpha.

85 Mechanistic studies revealed that HER2 trans-activation by IL-1beta required a disintegrin and

86 ation motif that abrogate acetylation reduce trans-activation by p300 without affecting the trans-rep

87 a deficiency drastically decreased NF-kappaB trans-activation by Tax, although it only modestly reduc

88 ransport function of AfAmt-2 also depends on trans-activation by the C terminus, and mutations in por

89 a minor role for the recruitment of RAC3 and trans-activation by the RXR/RAR heterodimer.

90 as platforms to concentrate procaspase-3 for trans-activation by upstream proteases.

91 The EGR1 promoter was engineered to enhance trans-activation capacity and optimized for simple scree

92 these modifications, both contribute to the trans-activation capacity of PEA3, implying that a dynam

93 minus of the Nmp4 protein exhibited a strong trans-activation capacity when fused to the GAL4 DNA-bin

94 tiates acetylation of PEA3, and enhances its trans-activation capacity.

95 F) by Tax is essential for the assembly of a trans-activation competent, nucleoprotein complex.

96 The results strongly suggest that the trans-activation deficient mutant is a more potent induc

97 However, the trans-activation deficient mutant of p53 is still more p

98 together, the results imply that employing a trans-activation deficient p53 in gene therapy approache

99 olic localization of endogenous wild-type or trans-activation-deficient p53 was necessary and suffici

100 orphic cis-regulations and to differences in trans-activation depending on the allelic form of the TF

101 Of note, LPS-induced trans-activation does not target this module, since it i

102 nant negative form of Egr-1, which lacks the trans activation domain but retains the DNA-binding doma

103 sponse element, suggesting the presence of a trans activation domain in IFNGR1.

104 The Tat trans activation domain is required for RON degradation,

105 code DNA-binding proteins with and without a trans-activation domain (TA- or Delta N-, respectively).

106 al for trans-activation, including an acidic trans-activation domain (TAD), a serine-rich tract (SRT)

107 for trans-activation mediated by the acidic trans-activation domain (TAD).

108 merization domains at the N terminus and the trans-activation domain at the C terminus.

109 PARalpha lacking the ligand-independent AF-1 trans-activation domain failed to inhibit STAT5b, highli

110 ucine zipper (bZIP) domain, a glutamine-rich trans-activation domain in CREB called Q2 also appeared

111 dominant-negative form of Stat5 lacking the trans-activation domain inhibited induction of cyclin D2

112 ng the HMG box domain of Lef-1 linked to the trans-activation domain of beta-catenin (Lef-1/beta-cat)

113 Notably, insertion of the glutamine-rich B trans-activation domain of SP1 into a mutant CREB polype

114 t LPS induced the phosphorylation of the p65 trans-activation domain on serine 536 in monocytes/macro

115 Instead, a 93-amino acid portion of the trans-activation domain was shown to be the minimal port

116 bitory effect of mutations in the C-terminal trans-activation domain were characterized.

117 Ap73alpha (the p73 isoform that contains the trans-activation domain) target gene and activates the e

118 lation is mediated by a cytosolic C-terminal trans-activation domain, which carries a conserved Thr (

119 tructs, we showed that the STRA13 C-terminal trans-activation domain, which is known to bind HDAC1, m

120 targeting sequence is encoded within the Sp2 trans-activation domain.

121 e 57, consistent with the deletions of their trans-activation domains at the C terminus.

122 AD1, one of the two trans-activation domains in BRCA1, stimulates transcript

123 binding site and exerts a position-dependent trans-activation effect on the dor promoter.

124 Trans-activation element DNA-binding protein of 43 kDa (

125 without apoptosis, a p53 mutant defective in trans-activation elicits apoptosis without inducing cell

126 demonstrate this autoactivation process is a trans-activation event that is efficiently inhibited by

127 trans-Activation experiments demonstrated diminished act

128 ng modules, by using a DNA binding assay and trans-activation experiments performed by analyzing prot

129 ion of the IRF-1 motif substantially reduces trans-activation from 5- to 2-fold and that inactivation

130 xpression, but did not significantly enhance trans-activation from a MHC class II promoter, indicatin

131 p53 protein (Ala135 to Val), which had lost trans-activation function and could not regulate G1/S tr

132 Treatment with C6-ceramide inhibited the trans-activation function of overexpressed Sp1, whereas

133 hibit productive infection suggests that the trans-activation function of Rta is essential for MHV-68

134 regulation, indicating that the synergistic trans-activation function of SRF and TEF-1 occurs via th

135 sfection assays, the IE protein inhibits the trans-activation function of the EICP0 protein.

136 tory gene promoters and directly inhibit the trans-activation function of the transcription factors R

137 Depressed E-cadherin correlated with HBxAg trans-activation function, as did the migration of HepG2

138 URG11 and beta-catenin correlated with HBxAg trans-activation function.

139 s both trans repression and ligand-dependent trans-activation function.

140 te that EWS-ATF-1 represses p53/CBP-mediated trans-activation function.

141 n responsive element TAR block Tat-dependent trans-activation in a HeLa cell assay when delivered by

142 t dose-dependent inhibition of Tat-dependent trans-activation in a HeLa cell assay when incubated for

143 construct, LPS and STF also induced HIV-LTR trans-activation in an additive manner.

144 of different types can inhibit Tat-dependent trans-activation in HeLa cells and have potential for de

145 ependent in vitro transcription and cellular trans-activation in HeLa cells.

146 m Staphylococcus epidermidis induced HIV-LTR trans-activation in human microvessel endothelial cells

147 This cis-activation process resembles trans-activation in its ligand level dependence, suscept

148 hin the DHFR promoter increased Sp2-mediated trans-activation in transient co-transfection experiment

149 inhibiting ability in vitro and increased AR trans-activation in vivo.

150 IE62 possesses several domains essential for trans-activation, including an acidic trans-activation d

151 he use of drugs that convert mutant p53 to a trans-activation-independent mediator of apoptosis may b

152 uman cells was increased by establishment of trans activation, indicating that Syg1 receptor-dependen

153 it apoptosis whereas p53 mutant deficient in trans-activation induces apoptosis.

154 or two OMe G-clamps did not impart cellular trans-activation inhibition activity to cellularly inact

155 inactive when delivered alone, but attained trans-activation inhibition in the presence of chloroqui

156 a major factor limiting nuclear delivery and trans-activation inhibition.

157 interact directly, this finding implies that trans activation is achieved via the DNA substrate in a

158 -1 replication, and that LPS-induced HIV-LTR trans-activation is mediated through myeloid differentia

159 h mycobacterial protein(s) induces HIV-1 LTR trans-activation is not clearly understood.

160 tion-dependent inhibition of DNA binding and trans-activation is the key primary mechanism of BES1 re

161 nstrate that cis-inhibition of SRK, like its trans-activation, is based on allele-specific interactio

162 C-terminal end of the positioning helix, the trans-activation loop, and the recognition helix of the

163 Such trans-activation may reflect control over HeT-A transcri

164 ads, although the mechanisms of EGF receptor trans-activation may vary.

165 FXIIa may activate fXI through a trans-activation mechanism in which the protease binds t

166 within the alphaherpesviruses, is needed for trans-activation mediated by the acidic trans-activation

167 ts were selectively defective in DHT-induced trans activation of androgen-responsive reporter genes a

168 from CD4(+) T cells and reveal a process of trans activation of DC without secretion of polarizing c

169 e (TBH) induces human GCLC via Nrf2-mediated trans activation of the antioxidant-responsive element (

170 nteraction domain on PRC is required for its trans activation of the cytochrome c promoter and a PRC

171 o T/EBP/NKX2.1 binding sites responsible for trans activation of the gene by T/EBP/NKX2.1 in lung cel

172 the release of NF-kappaB, in regulating the trans activation of the NF-kappaB subunit p65/RelA by af

173 ORF2 also interfered with Notch-mediated trans activation of the promoter that regulates the expr

174 We have shown that Ang II acts via "trans"-activation of the epidermal growth factor recepto

175 enhanced p53-dependent trans-repression and trans-activation of a subset of target genes.

176 mediates its biological effects through the trans-activation of a unique profile of target genes.

177 ys showed that they are both required in the trans-activation of alphabeta-INR-driven DNA templates.

178 ligomerisation, strength of DNA binding, and trans-activation of an artificial promoter.

179 were shown to be functional, potentially via trans-activation of associated G protein.

180 t co-expression of Brn-3b with p53 increases trans-activation of Bax promoter but not p21cip1/waf1.

181 se element modulator (CREM) and blocked both trans-activation of CCND2 by various myeloma oncogenes a

182 ifically, increased PXR binding triggers the trans-activation of critical drug-metabolizing enzymes a

183 Furthermore, trans-activation of cyclin D3 by ER-E2F1 occurs even in

184 ability to bind to E-box, and repressed the trans-activation of E-cadherin promoter.

185 aa) EICP0 protein that are important for the trans-activation of each class of EHV-1 promoters.

186 accompany changes in conformation during the trans-activation of enzymes; however, few studies exist

187 ng hormone (LH) receptor activation leads to trans-activation of epidermal growth factor (EGF) recept

188 esence of a C-terminal segment important for trans-activation of FAK.

189 Here we show that the the trans-activation of frameshifting is carried out by a pr

190 ght generate a CTCF binding site that blocks trans-activation of FSTL1 expression.

191 Trans-activation of gene expression by the four Arabidop

192 of their adverse effects are associated with trans-activation of genes involved with metabolic proces

193 activation is paradoxically antagonistic to trans-activation of hsp promoters by HSF1 and HSP accumu

194 of fibronectin in PaCa cells is mediated by trans-activation of IGF-IR induced by the beta3 integrin

195 ut not vitronectin and collagen I stimulated trans-activation of IGF-IR.

196 fibronectin protects from apoptosis through trans-activation of IGF-IR.

197 the first ATG abolished the EICP0 protein's trans-activation of its own promoter.

198 eporting system where GAL4-Elk and GAL4-CHOP trans-activation of luciferase gene served as reporters

199 both c-Jun and p38gamma are required for the trans-activation of MMP9.

200 another Sox member, Sox5, triggered no such trans-activation of mor DP-driven luciferase activity or

201 d by NF-kappaB relocation to the nucleus and trans-activation of NF-kappaB-targeted genes.

202 , but not PD098059, attenuates Nrf2-mediated trans-activation of pE1-luc.

203 hosphorylated SGK2 co-activates PXR-mediated trans-activation of promoters of gluconeogenic genes in

204 prevents their apoptosis by antagonizing the trans-activation of puma by p53.

205 ble DNA binding activity, but at best modest trans-activation of reporters containing Stat6 binding s

206 atocellular carcinoma (HCC), perhaps through trans-activation of selected cellular genes.

207 We also show that UBR5 specifically enhanced trans-activation of smooth muscle-specific promoters by

208 s as an antagonist that tightly controls the trans-activation of TGF-beta/Smad target genes.

209 Further, p53 trans-activation of the 14-3-3varsigma promoter was mark

210 Trans-activation of the activating transcription factor-

211 s of such complexes that may account for the trans-activation of the alphabeta-INR.

212 ation of c-Jun, which, in turn, enhances the trans-activation of the Annexin A2 promoter.

213 Herein trans-activation of the AR acetylation site mutants were

214 d shock-induced apoptosis or Notch1-mediated trans-activation of the bICP0 early promoter and stimula

215 O1 in sustaining the DZ program involved the trans-activation of the chemokine receptor CXCR4, and co

216 virus genome replication that relies on the trans-activation of the cRNP-associated RdRp.

217 -activated receptor gamma coactivator-1alpha trans-activation of the CYP7A1 gene.

218 ndent protein kinase (PKA) activity mediated trans-activation of the EGF receptor and subsequent mito

219 We demonstrated that, similar to the ovary, trans-activation of the EGF receptor was critical for go

220 is mediated by the Src/Pyk2 complex through trans-activation of the EGF-R.

221 -induced ERK phosphorylation is dependent on trans-activation of the EGF-R.

222 E(2)-EP4 receptor signalling did not lead to trans-activation of the epidermal growth factor receptor

223 -gamma-dependent NO generation increases the trans-activation of the Fas promoter, and this increase

224 n, achieving this by reducing AP-1-dependent trans-activation of the gene by way of compromised ERK a

225 lorophyll, and, as a result of cell-specific trans-activation of the hairpin to CS, chlorophyll accum

226 ble Brassicaceae is based on allele-specific trans-activation of the highly polymorphic S-locus recep

227 nal activity of the HRES-1/Rab4 promoter via trans-activation of the HRES-1 long terminal repeat.

228 tween bICP0 and IRF7 correlates with reduced trans-activation of the IFN-beta promoter by IRF7.

229 te that Id2 acts to repress the E2A-mediated trans-activation of the Il10 locus.

230 NO production, iNOS gene transcription, and trans-activation of the iNOS promoter in primary culture

231 trans-Activation of the intact CYP2C11 promoter (1.8-kil

232 mplicated in regulating ligand occupancy and trans-activation of the nuclear receptors belong to the

233 (2)O(2) induces tyrosine phosphorylation and trans-activation of the platelet-derived growth factor r

234 ooth muscle-specific genes and represses the trans-activation of the promoters of myocardin of these

235 glutamate to mimic phosphorylation increases trans-activation of the reporter in 293T cells and allow

236 negative cross-talk with an E2F-1-dependent trans-activation of the TERT promoter.

237 ransfection or 9-cis-RA treatment suppressed trans-activation of the TGF-beta-responsive promoter.

238 Increased trans-activation of these two sites also contributes to

239 Trans-activation of wild-type NOS3 promoter by FGF2 was

240 ion as dominant-negative mutants, inhibiting trans-activation of wild-type Rta.

241 ZIC proteins, that exhibit context dependent trans-activation or -repression activity.

242 ding domains within ZIC proteins that confer trans-activation or -repression.

243 SUMO-deficient mutant exhibited compromised trans-activation or trans-repression activities in repor

244 actors might serve to feedback inhibit their trans-activation potential and deactivate iNOS gene tran

245 A binding analysis demonstrated that loss of trans-activation potential by the A78D mutation resulted

246 ns contribute in a cooperative manner to the trans-activation potential of LEDGF.

247 h3, suggesting that ORF2 interfered with the trans-activation potential of Notch.

248 ORF2 reduced the trans-activation potential of Notch1 and Notch3, suggest

249 this repression is that p21SNFT inhibits the trans-activation potential of protein complexes that con

250 active RhoA suppressed KLF4 DNA binding and trans-activation potential on the PKG I promoter.

251 s revealed that PKA potently represses MEF2D trans-activation properties in neurons.

252 ibition required the viral Tat protein and a trans activation response region element.

253 These viral transcripts, which include trans-activation response (TAR) RNA and a novel RNA that

254 rates and how dsRNA binding proteins such as trans-activation response (TAR) RNA binding protein (TRB

255 The trans-activation response (TAR) RNA stem-loop that occur

256 tion factor b (pTEFb) complex onto the viral trans-activation response (TAR) RNA, leading to activati

257 l virus-associated RNA I (VA RNAI) and HIV-1 trans-activation response (TAR) RNA.

258 Trans-activation response DNA-binding protein (TDP-43) a

259 entary DNA and RNA hairpins derived from the trans-activation response domain of the HIV genome.

260 al mechanism for ligand-induced refolding of trans-activation response element (TAR RNA) from human i

261 Annealing of the trans-activation response element (TAR) DNA hairpin to a

262 ater by others using deep sequencing, is the trans-activation response element (TAR) miRNA.

263 promote KSHV infection, which depends on HIV trans-activation response element (TAR) RNA and EGFR of

264 mly (15)N/(13)C-labeled 27 nt variant of the trans-activation response element (TAR) RNA from HIV-I.

265 abilizes the highly structured complementary trans-activation response element (TAR) stem-loop (TAR D

266 V-associated saliva exosomes contain the HIV trans-activation response element (TAR), Tat, and Nef RN

267 ed score, STSCR: We tested the method on the trans-activation response element and Rev response eleme

268 on by polyinosinic:polycytidylic acid or HIV trans-activation response element RNA in lysates of T ce

269 terized transient excited state of the HIV-1 trans-activation response element stem-loop.

270 acterized RNA stem-loop structure, the HIV-1 trans-activation response element, showed that authentic

271 o small interfering RNA (siRNA), while human trans-activation response RNA-binding protein (TRBP) fun

272 roteins, protein activator of PKR (PACT) and trans-activation response RNA-binding protein (TRBP).

273 This screen identified Trans-activation Response RNA-binding protein 2 (Tarpb2)

274 d that binds the natural D-form of the HIV-1 trans-activation responsive (TAR) RNA.

275 The HIV-1 trans-activation responsive element (TAR) RNA 59-residue

276 nucleic acid residues complementary to HIV-1 trans-activation responsive element TAR block Tat-depend

277 pecific interactions of Tat protein with the trans-activation responsive region (TAR) RNA, a 59-base

278 pecific binding of P-TEFb onto nascent HIV-1 trans-activation responsive region (TAR) RNA.

279 human immunodeficiency virus type 1 (HIV-1) trans- activation-responsive (TAR) RNA.

280 protein essential for viral replication, and trans-activation-responsive (TAR) RNA.

281 this RNAi-enhancing activity depends on the trans-activation-responsive region RNA-binding protein.

282 o mechanical folding of RNA hairpins such as trans-activation-responsive RNA reveal distinct kinetic

283 The predicted network of pathways for trans-activation-responsive RNA suggests two parallel do

284 ters, need an RNA-associated P-TEFb/Tat/TAR (trans-activation-responsive) RNA ternary complex.

285 The TLR2 signaling pathway for NF-kappaB trans-activation shares the IL-1R signaling molecules.

286 Also, trans activation shortened the interval between initial

287 gel-free process including cis-blocking and trans-activation steps to support scalable generation of

288 ll complement the versatile cis-blocking and trans-activation strategy to broadly advance our ability

289 st two-hybrid assay to avoid the nonspecific trans-activation that would occur with the traditional y

290 ent Pdx1 expression and function depend upon trans-activation through 5' conserved cis-regulatory reg

291 of each with HCF-1 are also required for PRC trans-activation through promoter-bound NRF-2.

292 n cis amino acid activation competes with in trans activation to increase the range of amino acid sub

293 er p210(BCR-ABL)- and p185(BCR-ABL)-mediated trans-activation to an inert promoter.

294 by AP2gamma in mammary epithelial cells, and trans-activation was dependent upon the region of the pr

295 a modification that positively regulates its trans-activation, was concomitantly increased.

296 via unique mechanisms (BDNF independent TrkB trans-activation).We hypothesized that other GsPCRs elic

297 g a cell-based assay for inhibition of CCND2 trans-activation, we identified the plant cytokinin kine

298 conjugates entered the nucleus or inhibited trans-activation when freely delivered, but inhibition w

299 of ATF-2 and CREB produced (G)gamma-promoter trans-activation which was abolished by a 2-base pair mu

300 decreased NF-kappaB activation and p65/RelA trans activation without affecting I-kappaBalpha degrada