ライフサイエンスコーパス: transcriptional control

1 ross many organisms and readily linkable for transcriptional control.

2 tablished and recently described features of transcriptional control.

3 t is crucial for understanding developmental transcriptional control.

4 role of these negative regulators in fungal transcriptional control.

5 e3, implicating alternative roles for UTX in transcriptional control.

6 roles in DNA repair, cell-cycle arrest, and transcriptional control.

7 ich is implicated in cellular metabolism and transcriptional control.

8 enes is crucial for deciphering the logic of transcriptional control.

9 ability to uncover mechanistic principles of transcriptional control.

10 ation as one of the triggers for FACT-driven transcriptional control.

11 f in-house ccRCC cell lines suggested a post-transcriptional control.

12 f mTORC1 and PI3K-dependent, Akt-independent transcriptional control.

13 n are hardwired together through coordinated transcriptional control.

14 actors with the Pol II apparatus for precise transcriptional control.

15 matin interactions, resulting in coordinated transcriptional control.

16 latory and hierarchical interactions in post-transcriptional control.

17 intra-chromosomal contacts as it relates to transcriptional control.

18 ype consistent with its involvement in viral transcriptional control.

19 e the relationship between the epigenome and transcriptional control.

20 n acquisition systems that are under elegant transcriptional control.

21 caused an alteration in the kinetics of this transcriptional control.

22 mechanisms are crucial for cell identity and transcriptional control.

23 interactions and how these may impact on its transcriptional control.

24 ng MED18 function in different mechanisms of transcriptional control.

25 dvances in identifying mechanisms underlying transcriptional control.

26 nome in higher order structures required for transcriptional control.

27 roles in DNA repair, cell-cycle arrest, and transcriptional control.

28 that the presence of H2A.Z is not related to transcriptional control.

29 extend the agonist-sensitivity to fine-tune transcriptional control.

30 ain-of-function in chromatin recruitment and transcriptional control.

31 ce each other's expression, independently of transcriptional control.

32 genes required for chromatin regulation and transcriptional control.

33 networks connecting transcriptional and post-transcriptional control.

34 mmalian cells and used for DNA targeting and transcriptional control.

35 ail, much less is known about circadian post-transcriptional control.

36 been done on the mechanisms of gene-specific transcriptional control.

37 is fate specification hinges on a balance of transcriptional control.

38 lls are under tight transcriptional and post-transcriptional control.

39 s lysosomal biogenesis and functions through transcriptional controls.

40 ossible synergistic effect of GQs and HQs on transcriptional controls.

41 al regulation to be overlooked compared with transcriptional controls.

42 otropic functions involved in epigenetic and transcriptional controls.

43 This transcriptional control also exists in vivo, as we disco

44 at rely on a strong conditional promoter for transcriptional control and a low-expression marker gene

45 Increasing evidence suggests that transcriptional control and chromatin activities at larg

46 ry networks involved in the dysregulation of transcriptional control and chromatin remodeling.

47 rulence is regulated by a tight interplay of transcriptional control and chromatin remodelling.

48 Noncoding RNA plays essential roles in transcriptional control and chromatin silencing.

49 t, particularly in nuclear processes such as transcriptional control and DNA repair.

50 tch complements an earlier switch to zygotic transcriptional control and explains why the predominant

51 c mark in many organisms, important for both transcriptional control and genome integrity.

52 hanges, supporting the emerging concept that transcriptional control and nuclear positioning of TADs

53 rding the potential role of cohesin-mediated transcriptional control and pathogenesis.

54 via causal roles in dysregulated, malignant transcriptional control and represent one of the fastest

55 phenotype is under discrete tissue-selective transcriptional control and that this is fundamentally l

56 heir regulatory elements are key features of transcriptional control and their disruption can cause d

57 RNAs) have been ascribed regulatory roles in transcriptional control and their number is growing rapi

58 nsights into the topological determinants of transcriptional control and tissue-specific epigenetic m

59 lation of retinal phototransduction cascade, transcriptional control, and modulation of blood pressur

60 e applications in gene editing, programmable transcriptional control, and nucleic acid detection.

61 tify new roles for KLF1 in autophagy, global transcriptional control, and RNA splicing.

62 demonstrated the importance of rhythmic post-transcriptional controls, and it remains unclear how the

63 sites to survive in the context of regulated transcriptional control (apicomplexa) or in its absence

64 epair, alternative lengthening of telomeres, transcriptional control, apoptosis and senescence, are r

65 anization has a functional relevance, as the transcriptional control applied to each gene depends upo

66 cell wall modification, sugar transport, and transcriptional control are the key etiological factors

67 ncers, there is clear evidence for distorted transcriptional control as disease driver mechanisms.

68 n), we determined the relative importance of transcriptional control at each individual step of isopr

69 erences in chromatin structure and, thereby, transcriptional control, at the enhancer and promoter lo

70 lay more balanced functional loads and their transcriptional control becomes significantly more compl

71 de could increase NTCP protein level despite transcriptional control by a cytomegalovirus promoter.

72 oid treatment were distinct from those under transcriptional control by GR, suggesting an additional

73 emporally regulated exocyst components under transcriptional control by MAPKs.

74 primary regulatory region that mediates post-transcriptional control by microRNAs and RNA-binding pro

75 Post-transcriptional control by small regulatory RNA (sRNA) i

76 ulators are subject to sRNA regulation, post-transcriptional control by sRNAs allows multiple environ

77 The induction of GADD34 was dependent on transcriptional control by the c-Jun-binding cAMP respon

78 Our studies show that RpfA is subject to transcriptional control by the cyclic AMP receptor prote

79 n and, thus differentiation, is under direct transcriptional control by the transcription factor, ser

80 To unravel epigenetic mechanisms of transcriptional control, cell type-specific analysis of

81 To achieve circadian transcriptional control, chromatin remodelers serve the

82 e activities of cohesin, such as DNA repair, transcriptional control, chromosome loop formation, and/

83 e that our approach can uncover trans-acting transcriptional control circuits that affect co-regulate

84 Post-transcriptional control determines the fate of cellular

85 Cilia assembly is under strict transcriptional control during animal development.

86 We discuss the dynamic features of post-transcriptional control during CD8(+) T cell homeostasis

87 nces among Cre driver lines utilizing common transcriptional control elements affect germline recombi

88 Our method is able to identify transcriptional control elements in a gene specific mann

89 ten loss using recently characterized Hoxb13 transcriptional control elements that are active in pros

90 these factors in the recruitment of MED25 to transcriptional control elements.

91 rther highlight emergent connections between transcriptional control enacted by small RNAs and the co

92 lation of RAM1 and RAD1 and that the precise transcriptional control essential to place proteins in t

93 glycolytic metabolism and redox status, not transcriptional control, facilitate optimal NK cells res

94 ow the Ensemble approach extends our view on transcriptional control for TFs active in different biol

95 Although the transcriptional controls for alternative splicing of iso

96 tudy highlights the surprising and extensive transcriptional control GATA4 exercises over specialized

97 f early termination as an important means of transcriptional control has long been established.

98 regulator of epidermal development, but its transcriptional control has remained elusive.

99 To gain mechanistic insight into transcriptional control in B. burgdorferi, and address s

100 otes beta-catenin-mediated Wnt signaling and transcriptional control in breast cancer cell dedifferen

101 BNA3-regulated genes suggest that they exert transcriptional control in collaboration with epigenetic

102 ion and the patterning of root cell types by transcriptional control in conjunction with BIRD/INDETER

103 es involved in translational suppression and transcriptional control in DDX3Y-rescued GCLCs over muta

104 ur results suggest a so-far-unknown level of transcriptional control in eukaryotic cells.

105 e results suggest an integrated view of post-transcriptional control in human cells where most transl

106 etween somatic mutation, DNA methylation and transcriptional control in key B cell pathways deregulat

107 Transcriptional control in large genomes often requires

108 regulate TXNDC5 via ER stress/ATF6-dependent transcriptional control in lung fibroblasts.

109 us is subject to additional lineage-specific transcriptional control in mammary epithelium.

110 To elucidate transcriptional control in mouse ESCs in the naive, grou

111 r results demonstrate a key role of Clk post-transcriptional control in stabilizing circadian transcr

112 ique advantages that come with investigating transcriptional control in the multicellular context of

113 yet been applied to thedetailed modeling of transcriptional control in which mRNA production is cont

114 lock factors are transcription factors, post-transcriptional control introduces delays that are criti

115 Transcriptional control is a critical, yet largely unexp

116 Here, we discuss how transcriptional control is disrupted by genetic alterati

117 of chromatin insulators in alphaherpesvirus transcriptional control is less well understood.

118 primary gene regulators in kinetoplastids as transcriptional control is nearly absent, making Leishma

119 Transcriptional control is the major determinant of cell

120 revalence and functional impact of this post-transcriptional control layer requires technologies for

121 te pathways in the female germline as a post-transcriptional control layer to optimize oocyte composi

122 mechanism in which a mediator of long-range transcriptional control [LIM domain binding 1 (LDB1)] an

123 ssion, indicating that Arkadia's activity in transcriptional control may depend on the epigenetic con

124 We conclude that transcriptional control may underlie P vivax's resilienc

125 We have identified a novel viral transcriptional control mechanism in which a nucleosome

126 ations; and so far, our understanding of the transcriptional control mechanism of gene regulatory net

127 Here, we identified a post-transcriptional control mechanism, centered around the m

128 POBEC3B and APOBEC4 expression, indicating a transcriptional control mechanism.

129 We discuss the transcriptional control mechanisms downstream of both cy

130 Recently, transcriptional control mechanisms for individual genes

131 SY1 5'UTR, consistent with the prevalence of transcriptional control mechanisms in taxa with multiple

132 antitative PCR platform to gain insight into transcriptional control mechanisms of a subset of the mQ

133 To elucidate the transcriptional control mechanisms specifying the progen

134 es of stress response, indicating orthogonal transcriptional control mechanisms.

135 PUF RNA-binding protein (RBP) under complex transcriptional control mediated by a transposable eleme

136 Rhythmic transcriptional control mediated by the circadian transc

137 Together, our results suggest that a transcriptional control module regulates neuropeptide si

138 lly regulated component of the neuroblastoma transcriptional control network, that is essential for n

139 oteobacteria maintain a GUS operon under the transcriptional control of a glucuronide repressor, GusR

140 provide novel insights into tissue-specific transcriptional control of a housekeeping gene by a gene

141 targets and identify an additional layer of transcriptional control of a key growth factor regulatin

142 pendent motility in Escherichia coli via the transcriptional control of a key motility gene.

143 ncoded for by the aceI gene and is under the transcriptional control of AceR (Acinetobacter chlorhexi

144 This unusual transcriptional control of AeHO, together with the antio

145 fluorescent protein (mCherry) gene under the transcriptional control of an NF-kappaB response element

146 We hypothesize that transcriptional control of Aux/IAA genes plays a central

147 In contrast, the transcriptional control of axonal sorting and the role o

148 data is an effective means to delineate the transcriptional control of biological pathways.

149 We also discuss the physiology and transcriptional control of brown and beige cells in rode

150 e of BAF60a-mediated chromatin remodeling in transcriptional control of brown and beige gene programs

151 st, little is known about the extent of post-transcriptional control of caspases.

152 Although the transcriptional control of CD4(+)-CD8(+) lineage choice

153 While the transcriptional control of CD8 T cell differentiation an

154 n-focused network is closely associated with transcriptional control of cell growth and development.

155 Transcriptional control of cholesterol synthesis is rela

156 mmary,Drosophila mir-124 mutants reveal post-transcriptional control of circadian activities, and imp

157 However, the transcriptional control of circuit assembly in the cereb

158 sified into ILC1, ILC2 and ILC3 subsets, the transcriptional control of commitment to each ILC lineag

159 nstrained self-renewal in GBM stem cells via transcriptional control of core cell cycle and epigeneti

160 enter quiescence but fail to synchronize the transcriptional control of core cell cycle and metabolic

161 ility and differentiation, shed light on the transcriptional control of coronary microvascular matura

162 We describe a novel fundamental level of transcriptional control of COX-2 expression.

163 these data provide a novel mechanism of the transcriptional control of CPI-17 in vascular smooth mus

164 lso indicated that TAGL1 participates in the transcriptional control of cuticle development mediating

165 Studies on the transcriptional control of cytokine genes have mostly fo

166 of this gene family as leading actors in the transcriptional control of development.

167 scriptional regulators play central roles in transcriptional control of diverse physiological respons

168 chromatin insulators play a key role in the transcriptional control of DNA viruses.

169 established regulator of ECM remodeling via transcriptional control of ECM proteins.

170 or progression and metastasis through direct transcriptional control of effector target genes.

171 containing firefly luciferase and eGFP under transcriptional control of either element resulted in st

172 RNA-binding proteins (RBPs) facilitate post-transcriptional control of eukaryotic gene expression at

173 ess strong sequence identity suggesting that transcriptional control of expression is mediated by thi

174 (SNP)-specific manner, manifesting as a post-transcriptional control of expression of genetic polymor

175 t for retained introns and disruption of the transcriptional control of extracellular signal-regulate

176 In addition, there is feedforward transcriptional control of G-protein signaling component

177 our understanding of the combinatorial post-transcriptional control of gene expression at the 3' UTR

178 asingly understood, less is known about post-transcriptional control of gene expression by RNA-bindin

179 n antigen R (HuR) are key regulators in post-transcriptional control of gene expression in several pa

180 proteins (RBPs) play important roles in post-transcriptional control of gene expression, including sp

181 nt that Plasmodium falciparum exerts limited transcriptional control of gene expression, while at lea

182 domains, has several specific roles in post-transcriptional control of gene expression.

183 required for both cell-cycle regulation and transcriptional control of gene expression.

184 ese cells and found that, in addition to the transcriptional control of genes involved in the attract

185 ein-DNA interactions that participate in the transcriptional control of genes involved in the biosynt

186 ransmitter capable of triggering epigenetic, transcriptional control of genes required for establishi

187 Our understanding of the transcriptional control of glandular trichome initiation

188 Muscle Bmal1 deficiency impaired the transcriptional control of glucose metabolic pathway, re

189 veloping brain is the direct NMDAR-dependent transcriptional control of glutathione biosynthesis, dis

190 sulfur amino acid (SAA) metabolism is under transcriptional control of HNF4alpha.

191 al reveal a role for the kinase HIPK2 in the transcriptional control of IFN-I during antiviral immune

192 ulation of type 2 humoral immunity; however, transcriptional control of IL-4 production in Tfh cells

193 The striking similarities in transcriptional control of ILC and T cell lineages revea

194 tory processes in the transcriptional and co-transcriptional control of immune-responsive genes and d

195 ivatable guide RNAs enable temporal and post-transcriptional control of in vivo gene editing.

196 ory response, particularly by modulating the transcriptional control of inflammatory genes.

197 literature regarding the role of lncRNAs in transcriptional control of inflammatory responses.

198 Transcriptional control of iron-dependent gene expressio

199 ding proteins like RBM24 mediate in the post-transcriptional control of key transcription factors, na

200 uggest that regulatory mechanisms other than transcriptional control of LPPS regulate precursor parti

201 r signaling pathways has been described, the transcriptional control of LRO formation is poorly under

202 w discusses our current understanding of the transcriptional control of mammalian skeletal developmen

203 form a protein complex involved in the post-transcriptional control of many genes in vertebrates.

204 (+)-dependent deacetylase with a role in the transcriptional control of metabolism and aging but also

205 Transcriptional control of miR promoters was assessed vi

206 Such transposon-mediated post-transcriptional control of miR171 levels is conserved in

207 Direct transcriptional control of MITF by p300-dependent histon

208 Post-transcriptional control of mitochondrial gene expression

209 adipocytes and provide new insight into the transcriptional control of mitochondrial respiration.

210 igate the role of forkhead box P1 (FOXP1) in transcriptional control of MSC senescence.

211 specific candidates for proteins involved in transcriptional control of mtDNA replication.

212 ng Ang II-induced skeletal muscle atrophy by transcriptional control of MuRF1 via conserved E-box ele

213 These data provide a dynamic view of the transcriptional control of muscle identity in Drosophila

214 and they were both shown to be under direct transcriptional control of MYB.

215 es Myc quantity in individual cells via post-transcriptional control of Myc protein.

216 ndings represent a conceptual advance in the transcriptional control of myelin gene expression and st

217 s, directly implicating LXRalpha/beta in the transcriptional control of myelin gene expression.

218 Nevertheless, a clear logic underlying the transcriptional control of neuronal connectivity has yet

219 ation is unknown, past research demonstrated transcriptional control of neuropeptide synthesis sugges

220 Transcriptional control of nitrogen use is mediated in l

221 zebrafish strain, we document that this post-transcriptional control of Nrf2 activity is conserved at

222 R/NR1H4), maintains metabolic homeostasis by transcriptional control of numerous genes, including an

223 osperm, allows us to propose a model for the transcriptional control of oil FA composition in this ti

224 RRXRalpha) regulates bone mineralization via transcriptional control of osteocalcin (BGLAP) gene and

225 MRTF-A and YAP are also both required for transcriptional control of other S1P-regulated genes in

226 as genomic binding assays revealed a direct transcriptional control of PATS by TP53 signalling.

227 In addition to this transcriptional control of pcdh8l, adam13 cleaves pcdh8l

228 ty, indicating both transcriptional and post-transcriptional control of PHLDA1 expression.

229 back regulation that depends on the negative transcriptional control of phosphatidylinositol 3-kinase

230 Together, these studies implicate HIF in the transcriptional control of pulmonary adenosine signaling

231 dy, we sought to expand the understanding of transcriptional control of Ralpha2 in lung fibroblasts.

232 eins (RBPs) play important roles in the post-transcriptional control of RNAs.

233 Here, we investigated the transcriptional control of SARD1.

234 lies within our limited understanding of the transcriptional control of secondary cell wall biosynthe

235 In Arabidopsis (Arabidopsis thaliana), transcriptional control of seed maturation involves thre

236 These results directly link transcriptional control of SERCA2 activity, depressed SR

237 Transcriptional control of Sod2 expression was mediated

238 age molecules (possibly polyphosphate) and a transcriptional control of some genes coding for specifi

239 adversity leads to persistent alterations in transcriptional control of stress-responsive pathways, w

240 upporting a role for HOX5 proteins in direct transcriptional control of Th2 development.

241 Indeed, whereas transcriptional control of the atrophy-related genes pea

242 cyclical regulatory circuit that directs the transcriptional control of the Caulobacter cell cycle.

243 ATM signaling is mediated by transcriptional control of the cell cycle inhibitor SIAM

244 unanticipated role of the CAK branch in the transcriptional control of the cluster of genes implicat

245 nducible postnatal deletion of Dsp under the transcriptional control of the Cspg4 locus led to ventri

246 ntified as part of the Cue regulon under the transcriptional control of the cytoplasmic copper sensor

247 rogens regulate splicing through AR-mediated transcriptional control of the epithelial-specific splic

248 ing PhoP and transcription regulator EspR on transcriptional control of the espACD operon, which is r

249 Through transcriptional control of the evolutionarily conserved

250 ing, and is mediated by the symbiont gaining transcriptional control of the fungal ras2 gene, which e

251 omplementary strand which has cis-regulatory transcriptional control of the Il1a gene itself.

252 olutionarily conserved, intricate network of transcriptional control of the mammalian 12-h clock that

253 ) vectors to deliver the NPC1 gene under the transcriptional control of the neuronal-specific (CamKII

254 Rewiring of Puf-coordinated mRNA targets and transcriptional control of the same genes occurred at di

255 converge via double transcriptional and post-transcriptional control of the same protein, HRS1.

256 ates hemolysis and swarming motility through transcriptional control of the swrW gene and pigment pro

257 These findings support the loss of transcriptional control of the TGF-beta-MAPK-p38 pathway

258 udy reveals unrecognized roles of LXR in the transcriptional control of the tumor microenvironment an

259 These data suggest that transcriptional control of the vesicular GABA transporte

260 chanistic studies reveal Rev-erbalpha direct transcriptional control of two major myogenic mechanisms

261 We conclude post-transcriptional control of Xist RNA splicing is an essen

262 n of IL-12p70 by neonatal moDCs by unlocking transcriptional control on the p35 subunit of IL-12.

263 tory effect of SIRT3 on NLRP3 was not due to transcriptional control or priming of canonical inflamma

264 Along with its well-documented transcriptional control over cell-death programs within

265 transcripts, demonstrating that apoE exerts transcriptional control over miR-146a.

266 both proteins interact to facilitate optimal transcriptional control over the cbb operons.

267 m chloroplasts and mitochondria to establish transcriptional control over the metabolic processes in

268 While transcriptional controls over the size and relative posi

269 in mechanisms beyond microRNA-mediated post-transcriptional control, playing roles in DNA repair and

270 Comprehensive study of transcriptional control processes will be required to en

271 variation in Treg cells to identify the core transcriptional control program of lineage specification

272 with an increased functional effect of this transcriptional control protein.

273 This intersection of signaling and transcriptional control provides a framework to understa

274 ed analysis of miRNA expression patterns and transcriptional control regions.

275 elopment, their influence on chromatin-based transcriptional controls remains poorly explored.

276 Transcriptional control requires epigenetic changes dire

277 t of target mRNAs, where FBF-1-mediated post-transcriptional control requires the activity of CCR4-NO

278 ss MafB in adult mouse beta-cells using MafA transcriptional control sequences.

279 at pumps cysteine back out of the cell until transcriptional controls succeed in lowering the amount

280 Modeling of the potential roles of RNA in transcriptional control suggested a non-equilibrium feed

281 that cannot be linked directly with proximal transcriptional control, suggesting that widespread DNA

282 our results support a molecular mechanism of transcriptional control that allows an increase in N-dos

283 Thus, we illuminate a mechanism of transcriptional control that couples cell wall integrity

284 n axonal patterns, synaptic targets, and the transcriptional control that govern their connectivity i

285 te their significance for human disease, the transcriptional control that governs multiciliogenesis r

286 tioning of GAL1 to NPCs that is required for transcriptional control that is mediated by removal of S

287 tential for widespread dysregulation of post-transcriptional control that likely limits the effective

288 y adversity during puberty can enact lasting transcriptional control that manifests only during a uni

289 n is regulated through mRNA turnover, a post-transcriptional control that seems physiologically relev

290 tion factors (TFs) that play a major role in transcriptional control, thereby regulating genome-scale

291 Collectively, RBPJ links MYC and transcriptional control through CDK9, providing potentia

292 s modulated on multiple levels, ranging from transcriptional control to post-translational protein mo

293 nisms involved in PTEN-dependent genome-wide transcriptional control under metabolic stress.

294 resented here indicate that the finely tuned transcriptional control upon salt stress is dependent on

295 ing immunoproteasomes, TAP, and ERAP1, whose transcriptional control was previously poorly understood

296 udy the role of Oct1 in ESC pluripotency and transcriptional control, we constructed germline and ind

297 Post-transcriptional controls were found to regulate cell-typ

298 rx3 and Irx5 via epigenetic and beta-catenin transcriptional control where their ovarian presence pro

299 viously unrecognized layer of bacterial post-transcriptional control whereby mRNAs influence each oth

300 s have helped develop new models for dynamic transcriptional control with relevance across eukaryotes